CN114214186B - Device for rapidly detecting animal pathogens by using isothermal amplification technology - Google Patents

Device for rapidly detecting animal pathogens by using isothermal amplification technology Download PDF

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Publication number
CN114214186B
CN114214186B CN202111507780.5A CN202111507780A CN114214186B CN 114214186 B CN114214186 B CN 114214186B CN 202111507780 A CN202111507780 A CN 202111507780A CN 114214186 B CN114214186 B CN 114214186B
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locking
tube
sample
clamp
sliding
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CN114214186A (en
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王鑫
金哲
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Wuhan Yongding Medical Technology Co ltd
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Wuhan Yongding Medical Technology Co ltd
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/06Test-tube stands; Test-tube holders
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • B01L7/5255Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones by moving sample containers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The application belongs to the technical field of biological detection, and relates to a device for rapidly detecting animal pathogens by using a isothermal amplification technology, which has the technical scheme that the device comprises a PCR instrument, wherein a heating module is arranged in the PCR instrument, a sample plate with a sample or a sample tube with a sample is placed on the heating module, a tube clamp is sleeved around the sample plate or the sample tube, a bottom plate is detachably connected with the tube clamp, and a sliding component for sliding the tube clamp is arranged between the bottom plate and the tube clamp; locking components for positioning the pipe clamp are connected to two sides of the pipe clamp; the locking component is connected with a lifting device for lifting the pipe clamp, and an adsorption component for positioning the lifting device is arranged between the lifting device and the PCR instrument. The application has the advantages that the pipe clamp clamps the sample test tube, the lifting device can uniformly and slowly lift the pipe clamp, and the pipe clamp uniformly lifts the sample test tube, and the lifting speed is slow and uniform, so that the liquid in the sample test tube is difficult to splash to the top of the sample test tube.

Description

Device for rapidly detecting animal pathogens by using isothermal amplification technology
Technical Field
The application relates to the field of biological detection technology, in particular to a device for rapidly detecting animal pathogens by using isothermal amplification technology.
Background
The isothermal amplification technology is also a PCR gene amplification technology, a PCR nucleic acid amplification technology or a polymerase chain reaction nucleic acid amplification technology, is similar to the natural replication process of DNA, and the specificity of the isothermal amplification technology depends on oligonucleotide primers complementary to two ends of a target sequence and consists of three basic reaction steps of denaturation, annealing and extension, and is used for diagnosing certain genetic diseases and infectious diseases, for gene replication, paternity test and the like.
The prior Chinese patent with reference to publication No. CN111349543B discloses a device for rapidly detecting animal pathogens by using isothermal amplification technology, and a PCR instrument is divided into the following parts according to functions: the device comprises six modules, namely a base component, a thermal cover component, a temperature control module, an optical bracket component, an optoelectronic component and a control module. The base part is provided with a temperature control module, the temperature control module is used for amplifying a reagent in a sample test tube, the temperature control module can be opened and closed, after the temperature control module is opened, the sample test tube is placed on the sample module, then the temperature control module is closed to start a test, after the test is completed, the temperature control module is opened, and the test tube is discarded.
For the related art, the inventor considers that after the temperature control module heats the sample tube, the sample tube is stuck on the temperature control module due to high temperature, and when a worker pulls out the sample tube, the solution in the sample tube can splash to the top of the sample tube, so that the defect of inaccurate detection result is caused.
Disclosure of Invention
In order to solve the problem that when a worker pulls out a sample tube, a solution in the sample tube can splash to the top of the sample tube, the application provides a device for rapidly detecting animal pathogens by using a isothermal amplification technology.
The application provides a device for rapidly detecting animal pathogens by using a isothermal amplification technology, which adopts the following technical scheme:
the device for rapidly detecting the animal pathogen by using the isothermal amplification technology comprises a PCR instrument, wherein a heating module is arranged in the PCR instrument, a sample plate filled with a sample or a sample tube filled with the sample is placed on the heating module, a tube clamp is sleeved around the sample plate or the sample tube, a bottom plate is detachably connected with the tube clamp, and a sliding component for sliding the tube clamp is arranged between the bottom plate and the tube clamp; the pipe clamp is connected with a locking component for positioning the pipe clamp; the locking component is connected with a lifting device for lifting the pipe clamp, and an adsorption component for positioning the lifting device is arranged between the lifting device and the PCR instrument.
By adopting the technical scheme, the tube clamp is arranged, so that the tube clamp can clamp the sample test tube; the sliding component is arranged to enable the pipe clamp to slide on the bottom plate, so that the degree of clamping the sample test tube by the pipe clamp is adjusted; the pipe clamps are detachably connected with the bottom plate, so that staff can adjust the number of the pipe clamps according to the number of the sample test tubes placed on the heating module, the number of the sample test tubes is large, the number of the pipe clamps is large, the number of the sample test tubes is reduced, and the number of the pipe clamps is reduced; the locking component is arranged so that after the sample test tube is clamped by the tube clamp, the locking component positions the tube clamp; the setting of hoisting device for hoisting device can evenly slowly promote the pipe clamp, then the pipe clamp evenly lifts sample tube, because the speed of lifting is slow, and is at the uniform velocity, so the liquid in the sample tube is difficult to splash the top of sample tube.
Optionally, the pipe clamp is close to sample test tube one side and is wavy, and the pipe clamp is used for the centre gripping sample test tube.
Through adopting above-mentioned technical scheme, the wavy design of pipe clamp for the pipe clamp can be closely laminated with the outer wall of sample test tube, and then the pipe clamp is higher with the stability that the sample test tube was pressed from both sides, and when lifting means promoted the pipe clamp, the travel speed of pipe clamp was the same with the travel speed of sample test tube, guarantees that the liquid in the sample test tube is difficult to splash sample test tube top.
Optionally, the sliding component comprises a sliding block and a limiting edge, the sliding block is fixedly connected with one end of the pipe clamp, and a sliding groove is formed in the bottom of the sliding block; the limiting edge is fixedly connected to the bottom plate, is positioned in the sliding groove and is in sliding connection with the sliding block.
Through adopting above-mentioned technical scheme, the setting of subassembly that slides for when the staff prepares to fix a certain row of sample test tube, slide the pipe clamp at first, after the pipe clamp was equipped with the sample test tube clamp, rethread locking element locks the position of pipe clamp, then the sample test tube is established between the pipe clamp by firm clamp, when lifting means promoted the sample test tube, the liquid in the sample test tube was difficult to splash to the sample test tube top.
Optionally, the locking component includes locking strip and locking piece, has seted up the locking groove on the locking strip, locking piece and sliding block fixed connection, and the locking piece is located the locking inslot to with locking strip joint.
By adopting the technical scheme, the locking assembly is arranged, so that the locking strip locks the position of the locking block, the position of the sliding block connected with the locking block is locked by the locking block, and the position of the pipe clamp connected with the sliding block is locked; and easy operation only needs the staff to insert the locking piece in the locking strip, just can realize the fixed to the pipe clamp, presss from both sides the sample tube.
Optionally, a fixing bolt is connected between the locking strip and the bottom plate.
Through adopting above-mentioned technical scheme, the setting of gim peg for be fixed between locking strip and the bottom plate, then the relative position of locking strip is fixed, and the relative position of the pipe clamp of being connected with the locking strip is fixed.
Optionally, hoisting device includes lead screw and drive assembly, and the lead screw sets up to a plurality ofly, and the lead screw passes the locking strip to with locking strip threaded connection, lead screw deviates from locking strip one end and is connected with drive assembly.
Through adopting above-mentioned technical scheme, lead screw and drive assembly's setting for drive assembly drive lead screw rotates, and then lead screw drive bottom plate and locking strip upwards promote, and locking strip carries pipe clamp and upwards promotes with sample test tube, and the average speed pulls up sample test tube, then the sample in the sample test tube is difficult to splash sample test tube top.
Optionally, the drive assembly includes drive wheel, drive belt and motor, and the drive wheel sets up to a plurality ofly, drive wheel and lead screw threaded connection, and the axis fixed connection of motor and one of them drive wheel, drive belt and a plurality of drive wheels transmission connection.
Through adopting above-mentioned technical scheme, drive assembly's setting for the drive shaft of motor rotates and drives the drive wheel and rotate, and the drive wheel rotates and drives the drive belt and rotate, and when the drive belt rotated, a plurality of drive wheels that are connected with the drive belt rotated simultaneously, then drive wheel drive lead screw promotes locking strip and bottom plate, promotes the sample test tube indirectly.
Optionally, the adsorption component comprises an electromagnet and an iron block, wherein the electromagnet is connected with the motor, the iron block is connected with the PCR instrument, and the electromagnet is magnetically adsorbed with the iron block.
Through adopting above-mentioned technical scheme, the setting of adsorption component for the staff opens adsorption component, then the electro-magnet circular telegram, and the electro-magnet after the circular telegram can be with the firm absorption of iron plate, and the electro-magnet is in the same place with the firm connection of PCR appearance, then the hoisting device that is located the electro-magnet top can be stable promotes pipe clamp and sample tube, and sample in the sample tube is difficult to splash to sample tube top.
Optionally, the electromagnet is coated on the outer surface of the iron block and magnetically attracted with the iron block.
Through adopting above-mentioned technical scheme, the electro-magnet cladding is at the surface of iron plate, then proves that the area of contact of electro-magnet and iron plate is great, when the electro-magnet circular telegram, can with the firm absorption of iron plate to balanced hoisting device promotes the stability of sample test tube, prevents that the liquid in the sample test tube from splashing the sample test tube top.
In summary, the application comprises at least one of the following beneficial technical effects of a device for rapid detection of animal pathogens using isothermal amplification technology:
1. the tube clamp is arranged, so that the tube clamp can clamp a sample tube, the lifting device is arranged, the tube clamp can uniformly and slowly lift the sample tube, and the sample tube is lifted uniformly by the tube clamp, and the lifting speed is slow and uniform, so that liquid in the sample tube is difficult to splash to the top of the sample tube;
2. the locking assembly is arranged, so that the locking strip locks the position of the locking block, the position of the sliding block connected with the locking block is locked by the locking block, the position of the pipe clamp connected with the sliding block is locked, the operation is simple, the pipe clamp can be fixed by only inserting the locking block into the locking strip, and the sample test tube is clamped;
3. the setting of adsorption component for the staff opens adsorption component, then the electro-magnet circular telegram, and the electro-magnet after the circular telegram can be with the firm absorption of iron plate, and the electro-magnet is in the same place with the firm connection of PCR appearance, then is located the promotion subassembly of electro-magnet top and can stably promote pipe clamp and sample test tube, and sample in the sample test tube is difficult to splash sample test tube top.
Drawings
Fig. 1 is a schematic view intended to show the structure of embodiment 1 of the present application;
FIG. 2 is a schematic diagram of an exploded structure intended to show a hidden PCR instrument;
fig. 3 is a schematic view intended to show the structure of embodiment 2 of the present application;
fig. 4 is a schematic view of an exploded structure intended to show a locking assembly.
Reference numerals illustrate: 1. a PCR instrument; 11. a heating module; 2. a pipe clamp; 21. a first clamping plate; 22. a second clamping plate; 3. a bottom plate; 31. a first support plate; 32. a second support plate; 4. a slip assembly; 41. a sliding block; 411. a slip groove; 42. limit edges; 5. a locking assembly; 51. a locking bar; 511. a locking groove; 52. a locking block; 6. a lifting device; 61. a screw rod; 62. a drive assembly; 621. a driving wheel; 622. a drive belt; 623. a motor; 7. an adsorption assembly; 71. an electromagnet; 72. iron blocks; 8. a fixing bolt; 9. a connection frame; 91. and (3) a switch.
Detailed Description
The application is described in further detail below with reference to fig. 1-4.
Example 1
The embodiment of the application discloses a device for rapidly detecting animal pathogens by using a isothermal amplification technology. Referring to fig. 1, a device for rapidly detecting animal pathogens by using a isothermal amplification technology comprises a PCR instrument 1, a tube clamp 2, a bottom plate 3, a sliding component 4, a locking component 5, a lifting device 6 and an adsorption component 7, wherein a heating module 11 is arranged in the PCR instrument 1, the heating module 11 is used for heating a sample tube, and the sample tube can be independently placed or placed on a sample plate; the sample test tube is pressed from both sides to pipe clamp 2, and pipe clamp 2 and bottom plate 3, slip subassembly 4 are connected, and slip subassembly 4, bottom plate 3 are connected with locking subassembly 5, and bottom plate 3 is connected with hoisting device 6, and hoisting device 6 is connected with adsorption component 7, and adsorption component 7 is connected with PCR appearance 1.
When a worker prepares to pull out a sample tube from the heating module 11, firstly, the device for pulling out the sample tube is fixed on the PCR instrument 1 by using the adsorption component 7, then the tube clamp 2 is moved by using the sliding component 4, the sample tube is clamped by using the tube clamp 2, the position of the tube clamp 2 is locked by using the locking component 5, and finally, the tube clamp 2 and the sample tube clamped by the tube clamp 2 are lifted by using the lifting device 6, and the heating module 11 is lifted.
Referring to fig. 2, the bottom plate 3 is in a rectangular frame structure, the bottom plate 3 includes two first support plates 31 and two second support plates 32, the two second support plates 32 are arranged in two, the two first support plates 31 are arranged in parallel, the two second support plates 32 are arranged in parallel, the length direction of the first support plates 31 is perpendicular to the length direction of the second support plates 32, and the adjacent first support plates 31 are fixedly connected with the second support plates 32 and are integrally formed.
Referring to fig. 2, the pipe clamps 2 may be arranged in multiple groups, the multiple groups of pipe clamps 2 are all connected with the bottom plate 3, in this embodiment, the pipe clamps 2 are arranged in one group, the pipe clamps 2 include a first clamping plate 21 and a second clamping plate 22, the first clamping plate 21 and the second clamping plate 22 are both in long strip shapes, one side of the first clamping plate 21 is in a wavy shape, and the wavy side is just abutted against the outer wall of the sample test tube; the second clamping plate 22 has the same shape as the first clamping plate 21, but both the wavy side of the second clamping plate 22 and the wavy side of the first clamping plate 21 are positioned in the direction close to the sample tube.
Referring to fig. 2, two sets of sliding assemblies 4 are provided, the two sets of sliding assemblies 4 are respectively located at two ends of the first clamping plate 21, the sliding assemblies 4 comprise sliding blocks 41 and limiting edges 42, the sliding blocks 41 are in rectangular block structures, the sliding blocks 41 are located at one end of the first clamping plate 21 and are fixedly connected with the first clamping plate 21, and sliding grooves 411 are formed in the bottom surfaces of the sliding blocks 41; the limiting edge 42 is in a rectangular strip structure, the limiting edge 42 is fixedly connected with the bottom plate 3, is integrally formed, and is positioned in the sliding groove 411 and is in sliding connection with the sliding block 41.
Referring to fig. 2, the locking assemblies 5 are arranged in two groups, the two groups of locking assemblies 5 are symmetrically arranged with respect to the first clamping plate 21, and the locking assemblies 5 are positioned on the side of the sliding block 41 facing away from the first clamping plate 21. The locking assembly 5 comprises a locking strip 51 and a locking block 52, the locking strip 51 is in a rectangular strip structure, a fixing bolt 8 is arranged between the locking strip 51 and the bottom plate 3 and is fixedly connected through the fixing bolt 8, a plurality of locking grooves 511 are formed in the locking strip 51, the locking grooves 511 are in a hemispherical structure, and the locking grooves 511 are distributed on the locking strip 51 at equal intervals; the locking block 52 has a hemispherical structure, and the locking block 52 is positioned in the locking groove 511 and is clamped with the locking strip 51.
When the sample tube is clamped by the tube clamp 2, the tube clamp 2 is moved, the sliding block 41 slides on the bottom plate 3, the tube clamp 2 is attached to the outer wall of the sample tube, the locking strip 51 is close to the direction of the sliding block 41, the locking block 52 is inserted into the locking strip 51, and the locking block 52 is fixedly connected with the bottom plate 3 by the fixing bolt 8.
Referring to fig. 2, the lifting device 6 includes a plurality of screw rods 61 and a driving assembly 62, the number of screw rods 61 may be four in the present embodiment, the top ends of the screw rods 61 are inserted into the bottom plate 3 and are screwed with the bottom plate 3, and the bottom ends of the screw rods 61 are connected with the driving assembly 62. The driving assembly 62 is sleeved with a connecting frame 9, the connecting frame 9 is of a rectangular frame-shaped structure and is internally provided with a cavity, the driving assembly 62 comprises a driving wheel 621, a driving belt 622 and a motor 623, a lead screw 61 is inserted into the center of the driving wheel 621 and is connected with the driving wheel 621 in a key manner, the bottom end of one lead screw 61 is fixedly welded with the driving shaft of the motor 623, and the bottom end of the remaining lead screw 61 is rotationally connected with the connecting frame 9; the plurality of driving wheels 621 are all covered by the driving belt 622 and are in transmission connection with the driving belt 622.
After the sample tube is fixed, the motor 623 is started, the driving shaft of the motor 623 rotates to drive the driving wheel 621 to rotate, the driving wheel 621 drives the driving belt 622 to rotate, the driving belt 622 drives other driving wheels 621 to rotate, the driving wheel 621 drives the screw rod 61 to rotate, the screw rod 61 rotates and simultaneously lifts the bottom plate 3, then the tube clamp 2 connected with the bottom plate 3 is lifted at a constant speed, the sample tube clamped by the tube clamp 2 is lifted at a constant speed, and the sample tube is separated from the heating module 11 stably.
Referring to fig. 1 and 2, the adsorption assembly 7 is located below the connection frame 9 and connected to the connection frame 9, and a switch 91 for controlling the power on and off of the electromagnet 71 is provided on the connection frame 9. The adsorption assembly 7 comprises an electromagnet 71 and an iron block 72, the cross section of the electromagnet 71 is of a rectangular frame-shaped structure, and the longitudinal section of the electromagnet 71 is of a C shape; the iron block 72 is of a rectangular frame-shaped structure, the iron block 72 is fixedly connected with the PCR instrument 1 through bolts, and the electromagnet 71 coats the iron block 72 and is magnetically adsorbed with the iron block 72.
When the worker performs the preparation work, first, the electromagnet 71 is placed on the iron block 72, and then the switch 91 is turned on, and then the electromagnet 71 is tightly attracted to the iron block 72, and then the next operation is performed.
The embodiment 1 of the application provides a device for rapidly detecting animal pathogens by using isothermal amplification technology, which comprises the following implementation principles: when a worker performs preparation work, firstly, the electromagnet 71 is placed on the iron block 72, and when the switch 91 is opened, the electromagnet 71 is adsorbed on the iron block 72; then, moving the pipe clamp 2, attaching the pipe clamp 2 to the outer wall of the sample test tube, inserting the locking block 52 into the locking strip 51, and fixedly connecting the locking block 52 with the bottom plate 3 by using the fixing bolt 8; after the sample tube is fixed, the motor 623 is started, the driving shaft of the motor 623 rotates to drive the driving belt 622 to rotate, the driving belt 622 drives the driving wheel 621 to rotate, the driving wheel 621 drives the screw rod 61 to rotate, the screw rod 61 rotates and simultaneously lifts the bottom plate 3, then the tube clamp 2 connected with the bottom plate 3 is lifted at a constant speed, the sample tube clamped by the tube clamp 2 is lifted at a constant speed, the sample tube is separated from the heating module 11 stably, and samples in the sample tube are difficult to splash to the top of the sample tube.
Example 2
The difference from example 1 is that: referring to fig. 3 and 4, the locking assembly 5 includes a locking bar 51 and a locking block 52, the locking bar 51 has a rectangular bar structure, a fixing bolt 8 is disposed between the locking bar 51 and the bottom plate 3, and is fixedly connected with the fixing bolt 8, a locking groove 511 is formed on one side of the locking bar 51, which is close to the sliding block 41, and the locking groove 511 has a toothed belt structure; the locking block 52 is in a triangular prism shape, the locking block 52 is fixedly connected with the sliding block 41, and is integrally formed, and the locking block 52 is positioned in the locking groove 511 and is clamped with the locking strip 51.
The principle of implementation of a device for rapid detection of animal pathogens using isothermal amplification technology according to example 2 of the present application is the same as that of example 1.
The above embodiments are not intended to limit the scope of the present application, so: all equivalent changes in structure, shape and principle of the application should be covered in the scope of protection of the application.

Claims (5)

1. The utility model provides a device for detecting animal pathogen fast with isothermal amplification technique, includes PCR appearance (1), installs heating module (11), its characterized in that in PCR appearance (1): the heating module (11) is provided with a sample plate or a sample test tube filled with a sample, a tube clamp (2) is sleeved around the sample plate or the sample test tube, the tube clamp (2) is detachably connected with a bottom plate (3), and a sliding component (4) for sliding the tube clamp (2) is arranged between the bottom plate (3) and the tube clamp (2); the pipe clamp (2) is connected with a locking assembly (5) for positioning the pipe clamp (2); the locking assembly (5) is connected with a lifting device (6) for lifting the pipe clamp (2), and an adsorption assembly (7) for positioning the lifting device (6) is arranged between the lifting device (6) and the PCR instrument (1);
the tube clamp (2) is wavy at one side close to the sample test tube, and the tube clamp (2) is used for clamping the sample test tube;
the sliding assembly (4) comprises a sliding block (41) and a limiting rib (42), the sliding block (41) is fixedly connected with one end of the pipe clamp (2), and a sliding groove (411) is formed in the bottom of the sliding block (41); the limiting edge (42) is fixedly connected to the bottom plate (3), and the limiting edge (42) is positioned in the sliding groove (411) and is in sliding connection with the sliding block (41);
the locking assembly (5) comprises a locking strip (51) and a locking block (52), a locking groove (511) is formed in the locking strip (51), the locking block (52) is fixedly connected with the sliding block (41), and the locking block (52) is located in the locking groove (511) and is clamped with the locking strip (51);
a fixing bolt (8) is connected between the locking strip (51) and the bottom plate (3).
2. The apparatus for rapid detection of animal pathogens using isothermal amplification according to claim 1, wherein: the lifting device (6) comprises a plurality of lead screws (61) and a driving assembly (62), the lead screws (61) penetrate through the locking strips (51) and are in threaded connection with the locking strips (51), and one end, away from the locking strips (51), of each lead screw (61) is connected with the driving assembly (62).
3. A device for rapid detection of animal pathogens using isothermal amplification technology according to claim 2, wherein: the driving assembly (62) comprises driving wheels (621), driving belts (622) and motors (623), the driving wheels (621) are multiple, the driving wheels (621) are in threaded connection with the screw rods (61), the motors (623) are fixedly connected with the center shaft of one of the driving wheels (621), and the driving belts (622) are in transmission connection with the driving wheels (621).
4. The apparatus for rapid detection of animal pathogens using isothermal amplification according to claim 1, wherein: the adsorption component (7) comprises an electromagnet (71) and an iron block (72), wherein the electromagnet (71) is connected with a motor (623), the iron block (72) is connected with the PCR instrument (1), and the electromagnet (71) and the iron block (72) are magnetically adsorbed.
5. The apparatus for rapid detection of animal pathogens using isothermal amplification according to claim 4, wherein: the electromagnet (71) is coated on the outer surface of the iron block (72) and magnetically adsorbed with the iron block (72).
CN202111507780.5A 2021-12-10 2021-12-10 Device for rapidly detecting animal pathogens by using isothermal amplification technology Active CN114214186B (en)

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CN116536135B (en) * 2023-06-26 2023-09-22 鲲鹏基因(北京)科技有限责任公司 Auxiliary device of PCR instrument and PCR instrument

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CN214794118U (en) * 2021-05-28 2021-11-19 河北宝隆检验检测技术有限公司 Dry type nitrogen blowing instrument

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