CN114146134B - Traditional Chinese medicine composition with effects of warming channels and relieving pain and application thereof - Google Patents
Traditional Chinese medicine composition with effects of warming channels and relieving pain and application thereof Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine composition with functions of warming meridians and relieving pain and application thereof. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 1.5-2.5 parts of angelica, 1-2 parts of ligusticum wallichii, 1.8-2.2 parts of cinnamon, 1-2 parts of pericarpium zanthoxyli, 1.5-2.5 parts of corydalis tuber, 1.2-1.8 parts of evodia rutaecarpa, 0.5-1.5 parts of white paeony root, 1.5-2.5 parts of folium artemisiae argyi, 0.8-1.2 parts of rhizoma cyperi, 1.5-2.5 parts of herba lycopi and 1.5-2.5 parts of elecampane. The traditional Chinese medicine composition disclosed by the invention has the effects of warming channels for dispelling cold, regulating qi to alleviate pain, promoting blood circulation to remove meridian obstruction and the like, can be used for improving symptoms such as epigastric pain, lower abdominal pain and the like caused by deficiency-cold of spleen and kidney and obstruction of collaterals by blood stasis, and has the advantages of good curative effect, few side effects and the like.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition with functions of warming meridians and relieving pain and application thereof.
Background
Dysmenorrhea refers to the symptoms of pain in the lower abdomen or lumbosacral caused by pain during or before and after menstruation, which may be accompanied by nausea, vomiting, cold limbs, or syncope. Clinically, dysmenorrhea is classified into primary dysmenorrhea and secondary dysmenorrhea. Primary dysmenorrhea refers to the pain of the lower abdomen during menstruation when there is no organic disease in female genital organs; secondary dysmenorrhea is caused by organic lesions of female reproductive organs. Dysmenorrhea is common in unmarried and age-bearing women, and seriously affects the study, work and life of women.
According to the theory of traditional Chinese medicine, a large group of causes of primary dysmenorrhea, gastral cavity distending pain and lower abdominal pain are that the body cannot normally warm up due to cold pathogen or insufficiency of yang qi of the body. The pathogenic factors attacking the human body with the characteristics can cause the qi and blood of the human body to be condensed, the channels to be blocked, the qi and blood circulation to be unsmooth, and various discomforts and pains to the human body can be caused. The pain is fixed, even the pain has a cold feeling, and can be relieved when the pain is warm.
At present, western medicine conventional treatments for the diseases comprise oral Western medicine pain-relieving medicines and medicines for improving gastrointestinal spasm, and the Western medicine conventional treatments have the defects that after the effect of relieving pain for a short time is achieved, repeated attacks are easy to occur, and the physique of a patient cannot be fundamentally improved. The traditional Chinese medicine has acupuncture and moxibustion, oral traditional Chinese medicine and other treatment methods; for example, chinese patent publication No. CN107823594A discloses a traditional Chinese medicine for warming meridians, relieving pain, promoting blood circulation and removing blood stasis, which comprises the following components in parts by weight: 2-8 parts of selfheal, 8-15 parts of drynaria baronii, 5-10 parts of phellodendron, 10-20 parts of semen momordicae, 20-30 parts of ginger, 10-15 parts of gardenia and 5-10 parts of alpine yarrow herb; the preparation method comprises the following steps: a. mixing rhizoma Drynariae, cortex Phellodendri, semen Momordicae, rhizoma Zingiberis recens, and fructus Gardeniae, placing into a medicated bag, and soaking in 6-8L cold water for 20-40min; b. decocting with slow fire for 3-10min after boiling with strong fire; c. adding Prunellae Spica and herba Achilleae, decocting with slow fire for 3-10min, and boiling with strong fire for 3-8 min. The preparation method has a complex process, and the oral administration mode of the preparation method can not play the best drug effect and is easy to bring adverse reactions.
In view of the above, the present invention is particularly proposed.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition with the effects of warming channels and relieving pain and application thereof, the traditional Chinese medicine composition has the effects of warming channels and dispelling cold, regulating qi to relieve pain, promoting blood circulation and removing obstruction in channels and the like, can improve symptoms such as epigastric pain, lower abdominal pain and the like caused by deficiency-cold of spleen and kidney and obstruction of collaterals by blood stasis, and has the advantages of good curative effect, few side effects and the like.
The invention provides a traditional Chinese medicine composition with the effects of warming meridians and relieving pain, which comprises the following raw materials in parts by weight: 1.5-2.5 parts of angelica, 1-2 parts of ligusticum wallichii, 1.8-2.2 parts of cinnamon, 1-2 parts of pericarpium zanthoxyli, 1.5-2.5 parts of corydalis tuber, 1.2-1.8 parts of fructus evodiae, 0.5-1.5 parts of white paeony root, 1.5-2.5 parts of folium artemisiae argyi, 0.8-1.2 parts of rhizoma cyperi, 1.5-2.5 parts of herba lycopi and 1.5-2.5 parts of elecampane.
Further, the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 2 parts of angelica sinensis, 1.5 parts of ligusticum wallichii, 2 parts of cinnamon, 1.5 parts of pericarpium zanthoxyli, 2 parts of corydalis tuber, 1.5 parts of fructus evodiae, 1 part of radix paeoniae alba, 2 parts of folium artemisiae argyi, 1 part of rhizoma cyperi, 2 parts of herba lycopi and 1 part of elecampane.
The traditional Chinese medicine composition has the following effects of the raw materials:
chinese angelica root: is dried root of Angelica sinensis (oliv.) Diels of Umbelliferae; has the effects of enriching blood, promoting blood circulation, regulating menstruation, relieving pain, loosening bowel to relieve constipation and the like; it is commonly used for treating blood deficiency, sallow complexion, giddiness, palpitation, menoxenia, amenorrhea, dysmenorrhea, asthenia cold, abdominal pain, rheumatic arthralgia, traumatic injury, carbuncle, cellulitis, pyocutaneous disease, constipation due to intestinal dryness, and is mainly used for amenorrhea, dysmenorrhea, rheumatalgia, and traumatic injury.
Ligusticum wallichii: it is commonly used for activating blood and qi, dispelling wind and relieving pain; the rhizome of Sichuan lovage is pungent, warm, fragrant and dry, and can be scattered and ascended to the vertex; enter the blood system and descend to reach the blood sea; promoting blood circulation and removing blood stasis, and is suitable for various diseases caused by blood stasis; can be used for treating headache due to wind, and rheumatalgia.
Cinnamon: is dried bark of Cinnamomum cassia Presl of Lauraceae; has the effects of supplementing fire, supporting yang, guiding fire to the origin, dispelling cold, relieving pain, warming and dredging channels and collaterals and the like; is mainly used for cold womb, cold pain of waist and knees, asthma due to kidney deficiency, upward floating of deficiency yang, dizziness, conjunctival congestion, cold pain of heart and abdomen, vomiting and diarrhea due to deficiency cold, cold hernia and abdominal pain, dysmenorrheal and amenorrhea.
Pericarpium zanthoxyli: warming middle energizer to relieve pain, killing parasites to relieve itching; is mainly used for treating abdominal psychroalgia, emesis diarrhea, abdominal pain due to parasitic infestation; it can be used for treating eczema and pruritus vulvae.
Corydalis tuber: the tuber is used as a medicine, has the effects of promoting blood circulation, removing blood stasis, promoting qi circulation, relieving pain and the like, and is mainly used for treating diseases such as pain in heart, abdomen, waist and knees, traumatic injury, pain caused by blood stasis, irregular menstruation and the like.
Evodia fruit: has the effects of dispelling cold, relieving pain, lowering adverse qi, relieving vomit, supporting yang, and relieving diarrhea; is mainly used for treating jueyin headache, cold hernia abdominal pain, cold dampness beriberi, menstrual abdominal pain, abdominal distension and pain, vomiting and acid regurgitation, and morning diarrhea.
White peony root: has effects in warming yang, eliminating dampness, tonifying body, and invigorating spleen and stomach; can be used for treating rheumatism psychroalgia, rheumatic arthritis, lumbar muscle strain, asthenia, convulsion of limbs, chronic infantile convulsion, and dog bite.
Folium artemisiae argyi: warming channels to stop bleeding, dispelling cold and relieving pain; externally used for eliminating dampness and relieving itching; can be used for treating hematemesis, epistaxis, metrorrhagia, menorrhagia, vaginal bleeding, lower abdomen psychroalgia, menoxenia, and infertility due to cold womb.
Rhizoma cyperi: has the effects of soothing liver, relieving depression, regulating qi, relieving epigastric distention, regulating menstruation, relieving pain, and the like; can be used for treating stagnation of qi due to depression of the liver, distending pain in chest and hypochondrium, hernia pain, breast pain, stagnation of qi in spleen and stomach, abdominal distention and fullness, distention and pain, menoxenia, amenorrhea, and dysmenorrhea.
Herba lycopi: has pungent taste and warm nature, has effects of dispelling pathogenic wind, tranquilizing mind, expelling parasites and killing maggot, and can be used for treating arthralgia and rheumatism.
Costustoot: has the effects of promoting qi circulation, relieving pain, invigorating spleen, and promoting digestion; can be used for treating chest and hypochondrium, abdominal distention and pain, dysentery with diarrhea, tenesmus, dyspepsia, and anorexia. Roasted Aucklandia lappa Decne, radix aucklandiae and Cornus Sessima to relieve diarrhea. Can be used for treating diarrhea and abdominal pain.
The Chinese medicinal composition of the invention uses angelica and Szechuan lovage rhizome to nourish blood and promote blood circulation; white peony root, radix Paeoniae alba nourishes blood and soothes liver, relieves spasm and relieves pain; rhizoma Cyperi and rhizoma corydalis can promote qi circulation, relieve pain, and promote blood circulation to regulate menstruation; cinnamon, fructus evodiae and pericarpium zanthoxyli are used for dispelling cold and relieving pain, and warming and dredging channels and collaterals; radix aucklandiae has effects of activating qi-flowing and relieving pain; herba Lycopi can promote blood circulation, remove blood stasis, induce diuresis, and relieve swelling. The medicines have the effects of removing blood stasis, eliminating dampness, warming channels, nourishing blood, promoting qi circulation and relieving pain.
The invention also provides application of the traditional Chinese medicine composition in preparing a traditional Chinese medicine with the effects of warming meridians and relieving pain.
The invention also provides a navel patch for warming meridians and relieving pain, which comprises auxiliary materials and the traditional Chinese medicine composition.
The auxiliary materials used in the invention are not strictly limited, and the conventional auxiliary materials in the field can be used. Specifically, the adjuvant may include vaseline; in addition, the proportion of the auxiliary materials to the traditional Chinese medicine composition is 1g: (0.8-1.2) mL, preferably 1g:1mL.
The navel patch for warming channels and relieving pain belongs to the external treatment method of the traditional Chinese medicine, the specific traditional Chinese medicine composition is prepared into a patch dosage form and is applied to the Shenque point (navel), a skin channel is opened through the self-action of the specific traditional Chinese medicine, the medicine can be naturally absorbed through the skin, and therefore the stable and lasting treatment effect is achieved, the operation is simple, and the price is low.
The navel patch for warming meridians and relieving pain belongs to an acupoint application therapy, and is characterized in that the specific traditional Chinese medicine composition is applied to the navel (Shenque acupoint), and all raw materials in the traditional Chinese medicine composition mutually act synergistically, so that the efficacy of a medicine gradually penetrates into a local lesion part through skin acupoints, the influence of the medicine on passing through the liver and the digestive tract is avoided, and the optimal efficacy of the medicine is achieved; not only reduces the adverse reaction of the conventional oral administration, but also makes up the deficiency of the oral administration, and further improves the treatment effect.
The invention also provides a preparation method of the navel patch for warming meridians and relieving pain, which comprises the following steps:
s1: weighing the raw materials in parts by weight, crushing and sieving to obtain the traditional Chinese medicine composition;
s2: mixing the Chinese medicinal composition and adjuvants, and sterilizing to obtain unguent;
s3: coating the ointment on a carrier to obtain the navel patch for warming channels and relieving pain.
Specifically, in step S1, the sieving is 120-mesh sieving; in the step S2, sterilizing for 15-30min under the conditions of 98-147kPa and 115-123 ℃; in step S3, the ointment is prepared into an ointment cake with the thickness of 0.4-0.6cm and the diameter of 1.5-2cm, and then the ointment cake is coated on a carrier, wherein the carrier can adopt medical pressure-sensitive adhesive, ointment adhesive, membrane patch and the like.
The traditional Chinese medicine composition disclosed by the invention has the effects of warming channels for dispelling cold, regulating qi to alleviate pain, promoting blood circulation to remove meridian obstruction and the like, can be used for improving symptoms such as epigastric distending pain and lower abdominal pain caused by deficiency-cold of spleen and kidney and obstruction of collaterals by blood stasis, and has the advantages of good curative effect, few side effects and the like.
Detailed Description
It should be noted that the following detailed description is exemplary and is intended to provide further explanation of the disclosure. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs.
It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments according to the present application. As used herein, the singular forms "a", "an", and "the" include plural forms as well, unless the context clearly indicates otherwise, and it should be understood that when the terms "comprises" and/or "comprising" are used in this specification, they specify the presence of the stated features, steps, operations, devices, components, and/or combinations thereof.
The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments, and it should be understood that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be obtained by a person skilled in the art without making any creative effort based on the embodiments in the present invention, belong to the protection scope of the present invention.
Example 1
The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 2 parts of angelica sinensis, 1.5 parts of ligusticum wallichii, 2 parts of cinnamon, 1.5 parts of pericarpium zanthoxyli, 2 parts of corydalis tuber, 1.5 parts of fructus evodiae, 1 part of radix paeoniae alba, 2 parts of folium artemisiae argyi, 1 part of rhizoma cyperi, 2 parts of herba lycopi and 1 part of elecampane.
The navel patch for warming channels and relieving pain comprises an auxiliary material and the traditional Chinese medicine composition, wherein the auxiliary material is vaseline ointment, and the dosage ratio of the traditional Chinese medicine composition to the vaseline ointment is 100g:100mL.
The preparation method of the navel patch for warming meridians and relieving pain in the embodiment comprises the following steps:
the method comprises the following steps: weighing the traditional Chinese medicine raw materials according to the mass ratio, crushing the traditional Chinese medicine raw materials into fine powder, and sieving the fine powder through a 120-mesh medicine sieve to obtain the traditional Chinese medicine composition.
Step two: weighing medical vaseline ointment according to the proportion of 100g of the Chinese medicinal composition and 100mL of the medical vaseline ointment, placing into a stainless steel vessel, putting the vessel into 100 deg.C boiled water, melting into paste with water, adding the Chinese medicinal composition, stirring, and sterilizing at high temperature and high pressure in a high-pressure steam sterilization pot at 125kpa and 121 deg.C for 20min.
Step three: standing at 20-25 deg.C for 24 hr to obtain unguent. Placing the ointment in a ground closed container, and storing at 15-25 deg.C.
Step four: taking appropriate amount of unguent, making into unguent cake with thickness of about 0.5cm and diameter of about 1.8cm, and taking medical pressure sensitive adhesive as carrier to obtain meridian warming and pain relieving navel patch.
Example 2
The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 1.5 parts of angelica, 2 parts of ligusticum wallichii, 1.8 parts of cinnamon, 1 part of pericarpium zanthoxyli, 2.5 parts of corydalis tuber, 1.8 parts of evodia rutaecarpa, 0.5 part of white paeony root, 2.5 parts of folium artemisiae argyi, 1.2 parts of rhizoma cyperi, 1.5 parts of herba lycopi and 2.5 parts of elecampane.
The navel patch for warming channels and relieving pain comprises an auxiliary material and the traditional Chinese medicine composition, wherein the auxiliary material is vaseline ointment, and the dosage ratio of the traditional Chinese medicine composition to the vaseline ointment is 100g:100mL.
The preparation method of the meridian warming and pain relieving navel patch in the embodiment comprises the following steps:
the method comprises the following steps: weighing the traditional Chinese medicine raw materials according to the mass ratio, crushing the traditional Chinese medicine raw materials into fine powder, and sieving the fine powder with a 120-mesh medicine sieve to obtain the traditional Chinese medicine composition.
Step two: weighing medical vaseline ointment according to the proportion of 100g of the Chinese medicinal composition and 100mL of the medical vaseline ointment, placing into a stainless steel vessel, placing the vessel into 100 deg.C boiled water, melting into paste, adding the Chinese medicinal composition, stirring, and sterilizing at high temperature and high pressure in a high-pressure steam sterilization pot at 98kpa and 115 deg.C for 30min.
Step three: standing at 20-25 deg.C for 24 hr to obtain unguent. Placing the ointment in a ground closed container, and storing at 15-25 deg.C.
Step four: taking appropriate amount of unguent, making into unguent cake with thickness of about 0.4cm and diameter of about 2cm, taking unguent glue as carrier, and making into meridian warming and pain relieving navel patch.
Example 3
The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 2.5 parts of angelica, 1 part of ligusticum wallichii, 2.2 parts of cinnamon, 2 parts of pericarpium zanthoxyli, 1.5 parts of corydalis tuber, 1.2 parts of evodia rutaecarpa, 1.5 parts of white paeony root, 1.5 parts of folium artemisiae argyi, 0.8 part of rhizoma cyperi, 2.5 parts of herba lycopi and 1.5 parts of costustoot.
The navel patch capable of warming meridians to relieve pain comprises an auxiliary material and the traditional Chinese medicine composition, wherein the auxiliary material is vaseline ointment, and the dosage ratio of the traditional Chinese medicine composition to the vaseline ointment is 100g:100mL.
The preparation method of the navel patch for warming meridians and relieving pain in the embodiment comprises the following steps:
the method comprises the following steps: weighing the traditional Chinese medicine raw materials according to the mass ratio, crushing the traditional Chinese medicine raw materials into fine powder, and sieving the fine powder through a 120-mesh medicine sieve to obtain the traditional Chinese medicine composition.
Step two: weighing medical vaseline ointment according to the proportion of 100g of the Chinese medicinal composition and 100mL of the medical vaseline ointment, placing into a stainless steel vessel, putting the vessel into 100 ℃ boiled water, melting into paste by separating water, adding the Chinese medicinal composition, stirring, and sterilizing at high temperature and high pressure in a high pressure steam sterilization pot at 147kpa and 123 ℃ for 30min.
Step three: standing at 20-25 deg.C for 24 hr to obtain unguent. Placing the ointment in a ground closed container, and storing at 15-25 deg.C.
Step four: taking appropriate amount of unguent, making into unguent cake with thickness of about 0.6cm and diameter of about 1.5cm, and making into meridian warming and pain relieving navel patch with membrane patch as carrier.
Comparative example 1
The traditional Chinese medicine composition of the comparative example comprises the following raw materials in parts by weight: 1 part of clove, 2 parts of black monkshood, 2 parts of raw bighead atractylodes rhizome, 15g of raw rhubarb, 1 part of white paeony root, 1 part of cinnamon and 1 part of corydalis tuber.
The navel patch for warming meridians and relieving pain in the comparison example comprises an auxiliary material and the traditional Chinese medicine composition, wherein the auxiliary material is vaseline ointment, and the dosage ratio of the traditional Chinese medicine composition to the vaseline ointment is 100g:100mL, preparation method refer to example 1.
The early test proves that after the patient uses the navel patch for warming channels and relieving pain in the comparison example, part of the patients feel warm at the abdomen and can relieve part of flatulence symptoms, but the pain relieving effect is weak, and the stool frequency of part of the patients is increased and the patients are not shaped.
Test example 1
All cases in the experimental example are 24 cases of primary dysmenorrhea patients of Beijing combined traditional Chinese and western medicine hospital acupuncture department, preventive treatment department and gynecology from 2019 to 2021 within 10 months, and the age is 27-38 years.
1. Clinical data
1.1 diagnostic criteria
Western diagnostic criteria: refer to the Canadian Society of Obstetrics and Gynecology (SOGC) clinical guidelines for primary dysmenorrhea: the lower abdominal pain of women before or after several hours of menstruation may be accompanied by diarrhea, nausea, vomiting, fatigue, vertigo, headache, etc., even syncope and fever, which may affect the working and living people. The B-ultrasonic examination and the gynecological examination can eliminate the organic lesions of the reproductive organs.
1.2 inclusion criteria
(1) Those who meet PD diagnostic criteria; (2) substantially normal (28 ± 7) menstrual cycle d; (3) average pain level (pain visual analog scale score, VAS) over a 3 month continuous menstrual period of not less than 40mm; (4) voluntarily participate in the trial.
1.3 exclusion criteria
(1) Combined with the primary diseases seriously endangering life such as cardiovascular and cerebrovascular diseases, liver, kidney, hematopoietic system and the like, and asthma patients; (2) combining the medical history with other examinations, without excluding other suspected diseases; (3) patients with mental disorder, or with psychological disorder; (4) pregnant, preparing pregnant person; (5) treating dysmenorrhea patients who have taken medicines for preventing dysmenorrhea within 1 week before taking.
2. Method of treatment
The application method comprises the following steps: the navel patch for warming meridians and relieving pain in example 1 is applied to the Shenque acupoint every other day for 4-6 hours, and the 1-month menstruation period is one treatment course, and the treatment is continuously carried out for 3 treatment courses.
3. Observation of therapeutic effects
3.1 Observation index
Pain Visual Analogue Scale (VAS) score. Pain VAS score: and (3) evaluating by using a Visual Analog Scale (VAS), wherein the 0 end (0 point) represents 'no pain', the 100mm end (100 points) represents 'unbearable pain', the pain degree is marked on a scoring ruler by a patient according to the feeling, and the length (millimeter reading) from the 0 point to the marked point is the score of the pain degree. Pain is absent at 0-4mm, mild pain at 5-44mm, moderate pain at 45-74mm, and severe pain at 75-100 mm. The doctor assists in evaluation when the patient first visits, guides the patient to use a VAS scoring ruler and automatically records the VAS scoring of the most painful time point of the current menstrual period in a menstrual diary card. Evaluation was performed at 4 time points over the cycle, before treatment and at 1, 2, 3 months of treatment, respectively.
3.2 statistical treatment
Data analysis was performed using SPSS 19.0 statistical software. The measurement data is expressed by mean plus or minus standard deviation (x plus or minus s), the measurement data is compared in groups before and after treatment, if the measurement data obeys normal distribution and the variance is uniform, a matched sample t test is adopted; if the normal distribution is not obeyed, nonparametric tests are adopted. All statistical tests adopt bilateral test, and the difference is statistically significant when P is less than 0.05.
The patient's VAS score results after 1, 2, 3 month treatment cycles are shown in Table 1.
TABLE 1 VAS score comparison (min, +/-s) of 24 cases of primary dysmenorrhea patients at each time point before and after treatment
Note: * Representing P < 0.01 compared to pre-treatment.
The results show that:
after 1, 2 and 3 months of treatment, the VAS score of the patient is reduced compared with that before treatment (P is less than 0.01), and the effectiveness of the navel patch for warming channels and relieving pain is proved.
Typical cases are as follows:
case 1
A certain Liu, women, age 51, chief complaints: stomach cold, abdominal distension for 2 years.
The current medical history and symptoms: in 2 years, the abdomen becomes cold obviously, abdominal distension is felt occasionally, pain around the navel occurs seriously, lumbosacral becomes cold, the subjective qi is adverse, vexation, dry mouth is obvious, hypodynamia, short breath, no bitter taste in mouth, tidal fever, night sweat, and the patient can take the medicine, fall asleep, yellow urine and defecate for 1 time in 1 day. The work is tired at ordinary times, and the pressure is big. The thyroid nodule and hyperplasia of mammary glands are removed in 2021 year because of hysteromyoma. The same year gastroscopy indicates mild atrophic gastritis. Pale and dark tongue with white, thick and greasy coating and teeth marks.
And (3) Western diagnosis: atrophic gastritis.
Traditional Chinese medicine diagnosis: abdominal distention with heat at the upper part and cold at the lower part.
Treatment:
the effect of the granules is not obvious when the patient takes the granules for treating stomachache caused by qi stagnation by himself. The navel patch for warming channels and relieving pain in example 1 is externally used for 1 time every day, each time is 6 hours, and the patient is retested after 10 days, feels cool and has reduced abdominal distension and occasional onset of periumbilical pain, and continues to externally use the navel patch for warming channels and relieving pain, and after 1 month, the patient feels cool and has obviously reduced abdominal distension and abdominal pain, and the onset frequency and the degree of abdominal distension and abdominal pain are obviously reduced compared with the former case.
Case 2
Some jin, woman, age 67, complain: the lower abdomen has intermittent pain for more than 10 years.
The current medical history and symptoms: the lower abdomen falls and the left lower abdomen prick-like pain and vaginal secretion are rare and excessive after the climacteric period, and chronic pelvic inflammatory disease, vaginitis and somatotrophic anxiety disorder are diagnosed by the hospital and treated by Chinese and western medicines, so the effect is poor. The symptoms of hypodynamia, dry mouth, intolerance of cold, abdominal pain and cold feeling of the waist and the abdomen are caused by irregular time, and the symptoms are relieved by self hot compress or oral analgesic. Sleep is poor, anxiety is felt, stool is unformed and soft, 1 time per day, difficult urination is intermittent, obvious at night, and 2 times of nocturia. Past thyroid nodules. Dark red tongue with thin and white coating, deep and slippery right pulse and deep left pulse.
And (3) Western diagnosis: chronic pelvic inflammatory disease, vaginitis, and somatic anxiety.
Traditional Chinese medicine diagnosis: shaoyuan pain, cold stasis obstructing the collaterals.
Treatment:
the acupuncture and abdominal moxibustion is administered for 2 weeks, 2 times per week, 30 minutes each time, and the patient feels no pain on the day of acupuncture and has pain attacks at intervals. The navel patch for warming channels and relieving pain in example 2 is externally applied, the patch is continuously applied for 2 months 1 time a day, each patch is applied for 6 hours, the frequency of lower abdomen tenderness and left side lower abdominal acupuncture pricking pain of a patient is obviously reduced, the attack duration is shortened, and the analgesic is not taken orally any more. Meanwhile, the stool is not shaped and is obviously improved before, the urine is smooth before, and the nocturia is reduced to 1 time.
Case 3
Zhao somewhere, woman, age 35, chief complaints: dysmenorrhea was 2 years.
The current medical history and symptoms: the lower abdominal pain of the patient appears in the last 2 years in the 1 st and 2 nd days of menstruation, the patient needs to take analgesic orally, the normal work is affected, the menstrual flow is normal, the blood clots are more, the cycle is 28-31 days, and the menstruation lasts for 5 days. The patient has taken the traditional Chinese medicine orally in the hospital to treat dysmenorrhea, the pain is relieved when the patient takes the traditional Chinese medicine, and the pain is still obvious after the patient stops taking the traditional Chinese medicine. The gynecological system ultrasound did not suggest obvious abnormalities. The patient enjoys cold at ordinary times. The traditional Chinese medicine composition is obvious in dry mouth, pale in mouth, hypodynamia, poor in sleep, easy to wake up after falling asleep, dreamful, frequent nocturia and 1-time excrement day, and is formed.
Pale and dark tongue with thin coating, slightly superficial cun in the left pulse, deep chi and slippery cun in the right pulse.
And (3) Western diagnosis: dysmenorrhea.
Traditional Chinese medicine diagnosis: dysmenorrhea; discomfort of liver qi, cold stasis obstructing the collaterals.
Treatment:
the patient has acupuncture 5 times and each time for 30 minutes, and regular acupuncture cannot be performed due to busy work. Then, the navel patch for warming meridians and relieving pain in example 3 is used for external treatment, 1 time per day, 6-8 hours each time, and the patch is continuously applied during menstruation for 3 months. At the same time, the patient is advised to fast and get cold, and the patient is attentive to wear the clothes to keep warm and prevent from catching a cold. In the first month of treatment, dysmenorrhea was reduced earlier during menstruation, and no analgesic was taken. During the second and third months of menstruation, only the first day has slight pain, and the normal work can be realized. Meanwhile, the symptoms of frequent nocturia are obviously improved, and the nocturia is 0 to 1 time/night.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.
Claims (7)
1. The navel patch for warming channels and relieving pain is characterized by comprising auxiliary materials and a traditional Chinese medicine composition with the effects of warming channels and relieving pain, wherein the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 1.5-2.5 parts of angelica, 1-2 parts of ligusticum wallichii, 1.8-2.2 parts of cinnamon, 1-2 parts of pericarpium zanthoxyli, 1.5-2.5 parts of corydalis tuber, 1.2-1.8 parts of fructus evodiae, 0.5-1.5 parts of white paeony root, 1.5-2.5 parts of folium artemisiae argyi, 0.8-1.2 parts of rhizoma cyperi, 1.5-2.5 parts of herba lycopi and 1.5-2.5 parts of elecampane, and the proportion of the auxiliary materials to the traditional Chinese medicine composition is 1g:0.8-1.2mL.
2. The navel patch for warming meridians to relieve pain according to claim 1, wherein the Chinese medicinal composition comprises the following raw materials in parts by weight: 2 parts of angelica sinensis, 1.5 parts of ligusticum wallichii, 2 parts of cinnamon, 1.5 parts of pericarpium zanthoxyli, 2 parts of corydalis tuber, 1.5 parts of fructus evodiae, 1 part of radix paeoniae alba, 2 parts of folium artemisiae argyi, 1 part of rhizoma cyperi, 2 parts of herba lycopi and 1 part of elecampane.
3. The navel patch for warming meridians to relieve pain according to claim 1, wherein the auxiliary material comprises vaseline.
4. The preparation method of the navel patch for warming meridians to relieve pain of any one of claims 1 to 3, which is characterized by comprising the following steps:
s1: weighing the raw materials in parts by weight, crushing and sieving to obtain the traditional Chinese medicine composition;
s2: mixing the Chinese medicinal composition and adjuvants, and sterilizing to obtain unguent;
s3: coating the ointment on a carrier to obtain the navel patch for warming channels and relieving pain.
5. The method according to claim 4, wherein the sieving in step S1 is a 120-mesh sieving.
6. The method according to claim 4, wherein the sterilization is performed at 98 to 147kPa and 115 to 123 ℃ for 15 to 30 minutes in the step S2.
7. The method according to claim 4, wherein in step S3, the ointment is applied to the support after being formed into a cake having a thickness of 0.4 to 0.6cm and a diameter of 1.5 to 2 cm.
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