CN114129566A - 用于治疗肺腺癌的met、vegfr和ret的抑制剂 - Google Patents

用于治疗肺腺癌的met、vegfr和ret的抑制剂 Download PDF

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CN114129566A
CN114129566A CN202111124139.3A CN202111124139A CN114129566A CN 114129566 A CN114129566 A CN 114129566A CN 202111124139 A CN202111124139 A CN 202111124139A CN 114129566 A CN114129566 A CN 114129566A
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ret
compound
kif5b
fusion
gene
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D.T.阿夫塔布
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Exelixis Inc
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
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    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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CN202111124139.3A 2012-09-07 2013-09-09 用于治疗肺腺癌的met、vegfr和ret的抑制剂 Pending CN114129566A (zh)

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US201261698143P 2012-09-07 2012-09-07
US61/698143 2012-09-07
CN201380052164.2A CN104703600A (zh) 2012-09-07 2013-09-09 用于治疗肺腺癌的met、vegfr和ret的抑制剂

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US (2) US20150238477A1 (https=)
EP (1) EP2892532B1 (https=)
JP (2) JP6513567B2 (https=)
CN (2) CN114129566A (https=)
ES (1) ES2726605T3 (https=)
WO (1) WO2014039971A1 (https=)

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EP2892532A1 (en) 2015-07-15
WO2014039971A1 (en) 2014-03-13
US20140121239A1 (en) 2014-05-01
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