CN114129446A - Equipment and process for preparing Paracetamol, Caffein and chlorphenamine maleate capsules - Google Patents
Equipment and process for preparing Paracetamol, Caffein and chlorphenamine maleate capsules Download PDFInfo
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- CN114129446A CN114129446A CN202111374028.8A CN202111374028A CN114129446A CN 114129446 A CN114129446 A CN 114129446A CN 202111374028 A CN202111374028 A CN 202111374028A CN 114129446 A CN114129446 A CN 114129446A
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- 239000002775 capsule Substances 0.000 title claims abstract description 34
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 title claims abstract description 28
- 229960005489 paracetamol Drugs 0.000 title claims abstract description 26
- DBAKFASWICGISY-BTJKTKAUSA-N Chlorpheniramine maleate Chemical compound OC(=O)\C=C/C(O)=O.C=1C=CC=NC=1C(CCN(C)C)C1=CC=C(Cl)C=C1 DBAKFASWICGISY-BTJKTKAUSA-N 0.000 title claims abstract description 21
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 21
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 title claims description 14
- 239000003814 drug Substances 0.000 claims abstract description 57
- 238000002156 mixing Methods 0.000 claims abstract description 50
- 238000007670 refining Methods 0.000 claims abstract description 34
- 239000000463 material Substances 0.000 claims abstract description 32
- 238000000926 separation method Methods 0.000 claims abstract description 30
- 239000002245 particle Substances 0.000 claims abstract description 26
- 238000002360 preparation method Methods 0.000 claims abstract description 20
- 229940079593 drug Drugs 0.000 claims abstract description 15
- 238000007599 discharging Methods 0.000 claims abstract description 5
- 238000005520 cutting process Methods 0.000 claims description 36
- 239000000843 powder Substances 0.000 claims description 32
- 238000003860 storage Methods 0.000 claims description 22
- 238000003756 stirring Methods 0.000 claims description 16
- 239000006187 pill Substances 0.000 claims description 12
- 238000001514 detection method Methods 0.000 claims description 7
- 238000010410 dusting Methods 0.000 claims description 6
- 239000008187 granular material Substances 0.000 claims description 6
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 claims description 4
- 229960001948 caffeine Drugs 0.000 claims description 4
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 claims description 4
- 238000003466 welding Methods 0.000 claims description 4
- 238000004804 winding Methods 0.000 claims description 2
- 241000208829 Sambucus Species 0.000 claims 12
- 235000008995 european elder Nutrition 0.000 claims 12
- 238000000034 method Methods 0.000 claims 6
- 238000005516 engineering process Methods 0.000 claims 1
- 239000008188 pellet Substances 0.000 abstract description 32
- 230000000694 effects Effects 0.000 abstract description 11
- 238000011068 loading method Methods 0.000 abstract description 3
- 241000566137 Sagittarius Species 0.000 abstract 1
- 238000005507 spraying Methods 0.000 description 7
- 238000005192 partition Methods 0.000 description 6
- 239000012530 fluid Substances 0.000 description 5
- 239000000203 mixture Substances 0.000 description 4
- 239000002994 raw material Substances 0.000 description 4
- 238000005096 rolling process Methods 0.000 description 4
- 206010004542 Bezoar Diseases 0.000 description 3
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 description 3
- 230000005484 gravity Effects 0.000 description 3
- 238000012958 reprocessing Methods 0.000 description 3
- 238000007493 shaping process Methods 0.000 description 3
- 229940126589 solid medicine Drugs 0.000 description 3
- 241000037740 Coptis chinensis Species 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 230000000202 analgesic effect Effects 0.000 description 2
- 230000001754 anti-pyretic effect Effects 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 210000003169 central nervous system Anatomy 0.000 description 2
- 230000002490 cerebral effect Effects 0.000 description 2
- 239000003844 drug implant Substances 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010028748 Nasal obstruction Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 206010039101 Rhinorrhoea Diseases 0.000 description 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000001387 anti-histamine Effects 0.000 description 1
- 239000000739 antihistaminic agent Substances 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000003710 cerebral cortex Anatomy 0.000 description 1
- 229960001231 choline Drugs 0.000 description 1
- 230000002860 competitive effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000010339 dilation Effects 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000017525 heat dissipation Effects 0.000 description 1
- 229960001340 histamine Drugs 0.000 description 1
- 210000003016 hypothalamus Anatomy 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 208000010753 nasal discharge Diseases 0.000 description 1
- 210000002850 nasal mucosa Anatomy 0.000 description 1
- 201000009240 nasopharyngitis Diseases 0.000 description 1
- 208000004296 neuralgia Diseases 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 150000003180 prostaglandins Chemical class 0.000 description 1
- 239000011265 semifinished product Substances 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/003—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic followed by coating of the granules
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
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Abstract
The invention relates to the technical field of medicine production devices, in particular to an Paracetamol, Cabernet Sagittiflora and chlorphenamine maleate capsule particle preparation device and a preparation process thereof, wherein the Paracetamol, Cabernet Sagittarius and chlorphenamine maleate capsule particle preparation device comprises a main body, a power mechanism is arranged inside the main body, a refining mechanism is arranged at the top end of the power mechanism, a mixing mechanism is arranged at one end of the refining mechanism, a separation mechanism is arranged between the mixing mechanism and the refining mechanism, and a separation mechanism is connected onto the separation mechanism; the thinning mechanism is conveniently driven to pass through by the arrangement of the power mechanism, and the angle of the thinning mechanism can be adjusted, so that the discharging and preparing effects are better; the contour radian of the prepared drug pellet is better through the arrangement of the thinning mechanism, so that the drug particles have good trafficability, and the subsequent loading into capsules is facilitated; the semi-finished material can be cut and refined by the separation mechanism, the separation mechanism is conveniently covered on the medicine, and medicine particles are prevented from being adhered to the inner wall of the equipment.
Description
Technical Field
The invention relates to the technical field of medicine production devices, in particular to an equipment and a process for preparing Ankahuangmin capsule particles.
Background
An Ankahuangmin capsule for treating cold is prepared from paracetamol, caffeine, chlorphenamine maleate and artificial bezoar. Acetaminophen has analgesic and antipyretic effects, and can inhibit synthesis of prostaglandin in central nervous system and block impulse of pain nerve terminal to relieve pain, and regulate central blood vessel expansion, sweating and heat dissipation via hypothalamus temperature to relieve fever. Caffeine (small dose) acts on central nervous system of cerebral cortex to excite mental, relieve fatigue, and can contract cerebral vessels and relieve headache caused by cerebral vessel dilation. Chlorphenamine maleate is an antihistamine, has competitive blocking effect on histamine (H1) receptor, can relieve allergic symptoms, has effect of resisting M choline receptor, dries nasal mucosa, and can relieve nasal obstruction, watery nasal discharge, and sneeze symptoms caused by common cold. The artificial bezoar has effects of relieving fever and tranquilizing, relieving cough and eliminating phlegm, resisting bacteria, virus and allergy, activating acetaminophen, and enhancing antipyretic and analgesic effects.
However, most of the existing pellets in the amkehuangmin capsule are produced, and the viscosity of the pellets is added to the wall of a container, so that the pellets produced in the conventional amkehuangmin capsule have large roundness difference, the trafficability is greatly reduced, and the pellets are different in weight, so that the capsule sleeve is inconvenient to load and seal the pellets, and therefore, the device and the process for preparing the amkehuangmin capsule particles are provided.
Disclosure of Invention
Aiming at the problems in the prior art, the invention provides a preparation device and a preparation process of an Paracetamol, caffeine and chlorphenamine maleate capsule particle.
The technical scheme adopted by the invention for solving the technical problems is as follows: the device comprises a main body, wherein a power mechanism is arranged inside the main body, a refining mechanism is arranged at the top end of the power mechanism, a mixing mechanism is arranged at one end of the refining mechanism, a separating mechanism is arranged between the mixing mechanism and the refining mechanism, and a separating mechanism is connected to the separating mechanism.
Specifically, the mixing mechanism includes the blending tank, the one end of main part is equipped with the blending tank, the top of blending tank is equipped with first motor, fixedly connected with second mount between first motor and the blending tank, the first mount of fixedly connected with between blending tank and the main part.
Specifically, the first pivot of bottom fixedly connected with of first motor, the middle part fixedly connected with division board of first pivot, the top of division board is equipped with the stirring frame, the first pivot of stirring frame fixed connection, the bottom welding of first pivot has the flight.
Specifically, the separating mechanism comprises a separating pipe, the bottom end of the mixing tank is communicated with the separating pipe, a second motor is installed inside the separating pipe, and a second rotating shaft is fixedly connected to one end of the second motor.
Specifically, be equipped with two cutting pieces in the second pivot, one of them the cutting piece rotates and connects first pivot, and another one the cutting piece rotates and connects the second pivot, fixedly connected with first gear on the cutting piece, two the meshing has the second gear between the first gear.
Specifically, separating mechanism includes the storage cylinder, the top of separator tube is equipped with the storage cylinder, the bottom intercommunication of storage cylinder has the pipe of dusting, the bottom of dusting pipe extends to the inside of separator tube, the inside sliding connection of storage cylinder has first slider, logical groove has been seted up at the middle part of first slider.
Specifically, the top of first slider is contradicted there is the spring, be connected with the sleeve pipe between storage cylinder and the first slider, the bottom of dusting the pipe is equipped with the sieve, sieve fixed connection is on the inner wall of separator tube, the bottom of sieve is equipped with collects the box, collect the box and can dismantle the connection separator tube.
Specifically, refine the mechanism and include the cylinder, the top of main part is equipped with the cylinder, the outside welding of cylinder has two hoops, the inside of cylinder is equipped with the thin groove, the welding has a plurality of pick-up plates on the inner wall in thin groove.
Specifically, power unit includes the third pivot, the inside fixedly connected with of main part is the second, the third pivot, the inside sliding connection of main part has the second slider, fixedly connected with stopper on the second slider, the inside of main part is equipped with the place board, the place board rotates and connects the third pivot, place board sliding connection stopper, the bottom of second slider is rotated and is connected with the telescopic link, the inner wall of connecting the main part is rotated to the bottom of telescopic link.
Specifically, fixedly connected with fourth pivot on the second slider, it is connected with two support frames to rotate respectively in fourth pivot and the third pivot, it is connected with the contact wheel to rotate on the support frame, contact wheel roll connection barrel hoop, two fixedly connected with fifth pivot between the contact wheel, install the third motor on the mounting plate, respectively fixedly connected with runner, two in third motor and the fifth pivot the winding has the connecting band between the runner.
S1: when the main body is used for preparing the medicine, the mixing mechanism, the separating mechanism and the power mechanism are started in sequence, and meanwhile, enough medicine materials are added into the separating mechanism to finish preparation work;
s2: then, sequentially adding raw medicinal materials into the mixing mechanism, fully stirring a plurality of medicinal materials, then entering the separation mechanism for cutting and thinning, and scattering medicinal powder for avoiding bonding through the separation mechanism;
s3: at last, the power mechanism is started to drive the refining mechanism to operate, particles of scattered medicine powder sequentially enter the refining mechanism, the refining mechanism utilizes centrifugal force to roll pills, so that the profiles of the pills are more rounded, the passing performance of the pills is improved, the capsules are conveniently loaded in the later period to be sealed, and when the materials need to be discharged, the angle part inside the power mechanism is started, so that the refining mechanism is inclined at a certain angle, and the discharging of the pills is quicker.
The invention has the beneficial effects that:
(1) according to the device and the process for preparing the Ankahuangmin capsule particles, the power mechanism is arranged in the main body, the refining mechanism can be conveniently driven to pass through by the arrangement of the power mechanism, the angle of the refining mechanism can be adjusted, the discharging and preparing effects are better, the refining mechanism is arranged at the top end of the power mechanism, the radian of the outline of the prepared drug pellet is better by the arrangement of the refining mechanism, the passing performance of the drug particles is good, and the subsequent capsule loading is facilitated, namely: firstly, a third motor is started, one of the rotating wheels is driven to rotate by the third motor, the rotating wheel drives a fifth rotating shaft to rotate by a connecting belt, the second rotating shaft is in rolling friction with a drum hoop by a contact wheel, the drum hoop is fixedly connected with a drum, so that the drum can rotate quickly, the contact wheel can be prevented from being separated from the contact drum by the arrangement of the drum hoop, the contact between the contact wheel and the drum is good, after the drug pellets enter the drum, the drum rotating at a high speed causes the pellets to roll along the drum wall of the drum, so that the pellets can be subjected to a refined shaping effect, the radian of pellets is more standard, when the pellet particles meet the preparation standard, a telescopic rod is started, the second sliding block is driven to move towards the bottom end by the telescopic rod, the second sliding block simultaneously drives a placing plate to deflect, the second sliding block drives a supporting frame to shrink towards the inside of a main body, and the discharge end of the drum begins to tilt downwards, the inclination angles of the roller and the placing plate are the same, so that the roller can roll and the pellets can be conveniently discharged, the plurality of detection plates are distributed on the inner wall of the roller at the same interval, the prepared pellets can be discharged through the interval between the detection plates under the action of gravity, and unqualified pellets continue to be left in the roller for reprocessing, so that the quality of the pellets can be improved.
(2) According to the preparation equipment and the preparation process of the Paracetamol, disclosed by the invention, one end of the refining mechanism is provided with the mixing mechanism, and various raw materials of the medicine can be conveniently mixed through the arrangement of the mixing mechanism, so that the various materials are fully stirred, namely: when needs stir the material, at first start first motor, drive first pivot through first motor and rotate, pour the inside of blending tank into with medicine raw and other materials in proper order after that, first pivot drives the stirring frame and stirs the mixture to the material, the mouth of pipe that enters into the separator tube is higher than the bottom of blending tank, make the medicine only make into and be the mouth of pipe top that just can enter into of semifluid form, directly enter into the separator tube when can avoiding adding medicine raw and other materials through the setting of division board in, it rotates to drive the flight in step when first pivot rotates, the flight transmits the inside cutting that refines of separator tube with semisolid fluid form medicine.
(3) According to the preparation equipment and the preparation process of the Paracetamol, the separation mechanism is arranged between the mixing mechanism and the refining mechanism, the refined semi-finished product material can be cut through the arrangement of the separation mechanism, the separation mechanism material is conveniently covered on the medicine, the medicine particles are prevented from being adhered to the inner wall of the equipment, the separation mechanism is connected with the separation mechanism, the medicine powder for preventing adhesion is further scattered on the small-particle medicine through the arrangement of the separation mechanism, the medicine particles are prevented from being adhered to the inner wall of the equipment, and the prepared particle outline effect is better, namely: after the medicine enters the separating tube, a second motor is started, the second motor drives one of the cutting pieces to rotate at a high speed through a second rotating shaft, at the moment, one of the rotating first gears is in meshing transmission through the second gear, the other first gear rotates at a high speed, the other cutting piece rotates reversely at a high speed, and therefore the passing semi-solid medicine can be cut quickly, the two cutting pieces rotating synchronously and reversely can avoid cutting omission, when cutting and refining tasks are carried out, medicine powder is added into the storage barrel, the medicine powder can directly pass through the first sliding block and then reach the bottom end of the storage barrel, and finally the medicine powder is discharged into the separating tube through the powder spraying tube, so that the medicine powder can cover the outer surface of the passing cutting particles, the particles are prevented from being adhered to the inner wall of the device, and redundant unused medicine powder can be automatically collected into the collecting box through the sieve plate, thereby being capable of secondary use and avoiding waste of medicinal powder.
Drawings
The invention is further illustrated with reference to the following figures and examples.
FIG. 1 is a schematic structural diagram of the overall structure of a preferred embodiment of an apparatus for preparing Paracetamol, Coptis chinensis and Coptis chinensis capsules and a preparation process thereof according to the present invention;
FIG. 2 is a schematic view showing a connection structure of the mixing mechanism, the separating mechanism and the separating mechanism shown in FIG. 1;
FIG. 3 is a schematic view of the connection structure of the thinning mechanism and the power mechanism shown in FIG. 1;
FIG. 4 is an enlarged view of the part A shown in FIG. 1;
FIG. 5 is an enlarged view of the portion B shown in FIG. 1;
FIG. 6 is an enlarged view of the portion C shown in FIG. 2;
FIG. 7 is an enlarged view of the portion D shown in FIG. 2;
FIG. 8 is a flow chart of the manufacturing equipment and the manufacturing process of the Paracetamol, Caffein and chlorphenamine maleate capsules.
In the figure: 1. a main body, 2, a mixing mechanism, 21, a mixing tank, 22, a first fixing frame, 23, a first motor, 24, a first rotating shaft, 25, a separating plate, 26, a stirring frame, 27, a spiral sheet, 28, a second fixing frame, 3, a separating mechanism, 31, a separating pipe, 32, a second motor, 33, a second rotating shaft, 34, a cutting sheet, 35, a first gear, 36, a second gear, 4, a separating mechanism, 41, a storage barrel, 42, a first sliding block, 43, a through groove, 44, a cover closing plate, 45, a spring, 46, a sleeve, 47, a powder spraying pipe, 48, a sieve plate, 49, a collecting box, 5, a refining mechanism, 51, a roller, 52, a barrel hoop, 53, a refining groove, 54, a detection plate, 6, a power mechanism, 61, a third rotating shaft, 62, a fourth rotating shaft, 63, a supporting frame, 64, a placing plate, 65, a third motor, 66, a contact wheel, 67, a second sliding block, 68 and a limiting block, 69. the telescopic rod 69a, the connecting belt 69b, the fifth rotating shaft 69c and the rotating wheel.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.
As shown in fig. 1-8, the device for preparing the paracetamol and atificial cow-bezoar capsule particles and the preparation process thereof comprise a main body 1, wherein a power mechanism 6 is arranged inside the main body 1, a refining mechanism 5 is arranged at the top end of the power mechanism 6, a mixing mechanism 2 is arranged at one end of the refining mechanism 5, a separation mechanism 3 is arranged between the mixing mechanism 2 and the refining mechanism 5, and the separation mechanism 4 is connected to the separation mechanism 3.
Specifically, mixing mechanism 2 includes blending tank 21, the one end of main part 1 is equipped with blending tank 21, the top of blending tank 21 is equipped with first motor 23, fixedly connected with second mount 28 between first motor 23 and the blending tank 21, fixedly connected with first mount 22 between blending tank 21 and main part 1.
Specifically, a first rotating shaft 24 is fixedly connected to the bottom end of the first motor 23, a partition plate 25 is fixedly connected to the middle of the first rotating shaft 24, a stirring frame 26 is arranged at the top end of the partition plate 25, the stirring frame 26 is fixedly connected to the first rotating shaft 24, and a spiral plate 27 is welded to the bottom end of the first rotating shaft 24; refine the one end of mechanism 5 and be equipped with mixing mechanism 2, through mixing mechanism 2's setting and then be convenient for mix various medicine raw and other materials, make and obtain abundant stirring between the various materials, promptly: when materials need to be stirred, the first motor 23 is started firstly, the first motor 23 drives the first rotating shaft 24 to rotate, then raw materials of medicines are poured into the mixing tank 21 in sequence, the first rotating shaft 24 drives the stirring frame 26 to stir and mix the materials, the materials enter the pipe orifice of the separation pipe 31 and are higher than the bottom end of the mixing tank 21, so that the medicines can enter the top end of the pipe orifice only when being made into a semi-fluid shape, the raw materials of the medicines can be prevented from being added through the arrangement of the separation plate 25, the separation pipe 31 is directly entered into, the first rotating shaft 24 synchronously drives the spiral piece 27 to rotate when rotating, and the spiral piece 27 transmits the semi-solid fluid medicines into the separation pipe 31 to be finely cut.
Specifically, partition mechanism 3 includes separator tube 31, the bottom intercommunication of blending tank 21 has separator tube 31, separator tube 31 internally mounted has second motor 32, the one end fixedly connected with second pivot 33 of second motor 32.
Specifically, be equipped with two cutting pieces 34 on the second pivot 33, one of them cutting piece 34 rotates and connects first pivot 33, and the other cutting piece 34 rotates and connects second pivot 33, fixedly connected with first gear 35 on the cutting piece 34, two the meshing has second gear 36 between the first gear 35.
Specifically, the separating mechanism 4 includes a storage barrel 41, the storage barrel 41 is arranged at the top end of the separating tube 31, a powder spraying tube 47 is communicated with the bottom end of the storage barrel 41, the bottom end of the powder spraying tube 47 extends into the separating tube 31, a first sliding block 42 is slidably connected inside the storage barrel 41, and a through groove 43 is formed in the middle of the first sliding block 42; mixing mechanism 2 and refine and be equipped with partition mechanism 3 between the mechanism 5, through partition mechanism 3 set up and then can cut and refine semi-manufactured goods material, and the convenience will separating mechanism 4 material covers on the medicine, avoids the adhesion of medicine granule on the equipment inner wall, be connected with separating mechanism 4 on partition mechanism 3, through separating mechanism 4's setting and then toward the medicine of scattering the powder of avoiding the adhesion on the tiny particle medicine, avoid the medicine granule to glue the equipment inner wall, make the granule profile effect of preparing better, promptly: after the medicine enters the separating tube 31, the second motor 32 is started, the second motor 32 drives one of the cutting blades 34 to rotate at a high speed through the second rotating shaft 33, at this time, the rotating one of the first gears 35 is driven by the meshing of the second gear 36 to rotate the other one of the first gears 35 at a high speed, the other one of the cutting blades 34 rotates in a reverse direction at a high speed, so that the passing semi-solid medicine can be cut rapidly, the two cutting blades 34 rotating in the reverse direction synchronously can avoid missing of cutting, when a cutting and thinning task is performed, powder is added into the storage barrel 41, the powder can directly pass through the first sliding block 42 and further reach the bottom end inside the storage barrel 41, and is finally discharged into the separating tube 31 through the powder spraying tube 47, so that the outer surface of the passing cutting particles can be covered with the powder, avoid the granule to glue at the inner wall of device, unnecessary unused powder can be automatic through sieve 48 is concentrated inside collecting box 49, and then can the secondary use, avoid extravagant powder.
Specifically, the top end of the first sliding block 42 is abutted to a spring 45, a sleeve 46 is connected between the storage cylinder 41 and the first sliding block 42, a sieve plate 48 is arranged at the bottom end of the powder spraying pipe 47, the sieve plate 48 is fixedly connected to the inner wall of the separation pipe 31, a collection box 49 is arranged at the bottom end of the sieve plate 48, and the collection box 49 is detachably connected with the separation pipe 31.
Specifically, the thinning mechanism 5 comprises a roller 51, the roller 51 is arranged at the top end of the main body 1, two pipe hoops 52 are welded on the outer side of the roller 51, a thinning groove 53 is arranged in the roller 51, and a plurality of detection plates 54 are welded on the inner wall of the thinning groove 53.
Specifically, power unit 6 includes third pivot 61, the inside fixedly connected with of main part 1 is the second, third pivot 61, the inside sliding connection of main part 1 has second slider 67, fixedly connected with stopper 68 on the second slider 67, the inside of main part 1 is equipped with place board 64, place board 64 rotates and connects third pivot 61, place board 64 sliding connection stopper 68, the bottom of second slider 67 is rotated and is connected with telescopic link 69, the inner wall of connecting main part 1 is rotated to the bottom of telescopic link 69.
Specifically, a fourth rotating shaft 62 is fixedly connected to the second slider 67, the fourth rotating shaft 62 and the third rotating shaft 61 are respectively and rotatably connected to two supporting frames 63, a contact wheel 66 is rotatably connected to the supporting frame 63, the contact wheel 66 is in rolling connection with the barrel hoop 52, a fifth rotating shaft 69b is fixedly connected between the two contact wheels 66, a third motor 65 is installed on the placing plate 64, rotating wheels 69c are respectively and fixedly connected to the third motor 65 and the fifth rotating shaft 69b, and a connecting belt 69a is wound between the two rotating wheels 69 c; the inside of main part 1 is equipped with power unit 6, through power unit 6's setting and then be convenient for drive refine mechanism 5 passes through, and can adjust refine the angle of mechanism 5, make the ejection of compact better with the preparation effect, power unit 6's top is equipped with refines mechanism 5, through refine the setting of mechanism 5 and then prepare the medicine pellet profile radian better, make the medicine granule trafficability characteristic good to convenient follow-up loading is into the capsule, promptly: firstly, the third motor 65 is started, the third motor 65 drives one of the rotating wheels 69c to rotate, the rotating wheel 69c drives the fifth rotating shaft 69b to rotate through the connecting belt 69a, the second rotating shaft 69b rolls and rubs the drum hoop 52 through the contact wheel 66, the drum hoop 52 is fixedly connected with the drum 51, so that the drum 51 can rotate quickly, the contact wheel 66 can be prevented from being separated from the drum 51 through the arrangement of the drum hoop 52, the contact between the contact wheel 66 and the drum 51 is good, after a drug pellet enters the drum 51, the drum 51 rotating at high speed causes the pellet to roll along the drum wall of the drum 51, so that the fine shaping effect can be performed on the pellet, the radian of the pellet particles is more standard, when the pellet particles meet the preparation standard, how to start telescopic link 69, utilize telescopic link 69 drives second slider 67 moves toward the bottom, then second slider 67 drives simultaneously place board 64 deflects, second slider 67 drives support frame 63 toward the inside shrink of main part 1, then the discharge end of cylinder 51 begins the downward sloping, cylinder 51 with place board 64's inclination is the same, thereby can make cylinder 51 keeps rolling convenient pellet to discharge simultaneously, and is a plurality of pick-up plate 54 is same clearance distribution and is in on the inner wall of cylinder 51, and the pellet that is prepared can pass through under the action of gravity the clearance between the pick-up plate 54 is discharged, and unqualified then continues to remain the inside reprocessing that carries out of cylinder 51, and then can improve the quality of pellet.
S1: when the main body 1 is used for preparing medicines, the mixing mechanism 2, the separating mechanism 3 and the power mechanism 6 are started in sequence, and meanwhile, enough medicine materials are added into the separating mechanism 4 to finish preparation work;
s2: then, raw medicinal materials are sequentially added into the mixing mechanism 2, a plurality of medicinal materials are fully stirred, then the medicinal materials enter the separation mechanism 3 for cutting and thinning, and the separation mechanism 4 is used for scattering medicinal powder which avoids bonding;
s3: at last, the power mechanism 6 is started to drive the refining mechanism 5 to operate, particles of scattered medicine powder sequentially enter the refining mechanism 5, the refining mechanism 5 utilizes centrifugal force to roll pills, so that the profiles of the pills are more rounded, the passing performance of the pills is improved, the capsules are conveniently loaded at the later stage to be sealed, and when the materials need to be discharged, the angle part inside the power mechanism 6 is started to enable the refining mechanism 5 to be inclined at a certain angle, so that the discharging of the pills is quicker.
When the invention is used, firstly, the third motor 65 is started, one of the rotating wheels 69c is driven to rotate by the third motor 65, the fifth rotating shaft 69b is driven to rotate by the rotating wheel 69c through the connecting belt 69a, the second rotating shaft 69b is in rolling friction with the drum hoop 52 through the contact wheel 66, the drum hoop 52 is fixedly connected with the drum 51, so that the drum 51 can rotate quickly, the contact wheel 66 can be prevented from being separated from the contact drum 51 through the arrangement of the drum hoop 52, the contact between the contact wheel 66 and the drum 51 is good, after the drug pellets enter the drum 51, the drum 51 rotating at high speed causes the pellets to roll along with the drum wall of the drum 51, so that the fine shaping effect can be carried out on the pellets, the radian of the pellets is more standard, when the pellets meet the preparation standard, the telescopic rod 69 is started, the telescopic rod 69 is utilized to drive the second sliding block 67 to move towards the bottom end, and the second sliding block 67 simultaneously drives the setting plate 64 to deflect, the second sliding block 67 drives the supporting frame 63 to contract towards the inside of the main body 1, the discharge end of the roller 51 begins to incline downwards, the inclination angles of the roller 51 and the placing plate 64 are the same, so that the roller 51 can roll and the pellets can be conveniently discharged, the plurality of detection plates 54 are distributed on the inner wall of the roller 51 at the same interval, the prepared pellets can be discharged through the interval between the detection plates 54 under the action of gravity, and unqualified pellets are continuously stored in the roller 51 for reprocessing, so that the quality of the pellets can be improved; when the materials need to be stirred, the first motor 23 is started firstly, the first motor 23 drives the first rotating shaft 24 to rotate, then the raw materials of the medicines are poured into the mixing tank 21 in sequence, the first rotating shaft 24 drives the stirring frame 26 to stir and mix the materials, the materials enter the pipe orifice of the separation pipe 31 and are higher than the bottom end of the mixing tank 21, so that the medicines can enter the top end of the pipe orifice only when being made into a semi-fluid shape, the medicines can be prevented from directly entering the separation pipe 31 when being added through the arrangement of the separation plate 25, the spiral plate 27 is synchronously driven to rotate when the first rotating shaft 24 rotates, and the spiral plate 27 transmits the semi-solid fluid medicines into the separation pipe 31 for thinning and cutting; after the medicine enters the separating tube 31, the second motor 32 is started, the second motor 32 drives one of the cutting blades 34 to rotate at a high speed through the second rotating shaft 33, at the moment, one of the rotating first gears 35 is in meshing transmission through the second gear 36, so that the other first gear 35 rotates at a high speed, the other cutting blade 34 rotates reversely at a high speed, and thus the passing semi-solid medicine can be cut rapidly, the two cutting blades 34 rotating synchronously and reversely can avoid cutting omission, when cutting and thinning tasks are carried out, medicine powder is added into the storage barrel 41, the medicine powder can directly pass through the first sliding block 42 and then reach the bottom end of the interior of the storage barrel 41, and finally the medicine powder is discharged into the separating tube 31 through the powder spraying tube 47, so that the medicine powder can be coated on the outer surface of the passing cutting particles, the particles are prevented from being adhered to the inner wall of the device, and the surplus unused medicine powder can be automatically concentrated into the collecting box 49 through the sieve plate 48, thereby being capable of secondary use and avoiding waste of medicinal powder.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (10)
1. The utility model provides an Paracetamol, caffeine and chlorphenamine maleate capsule granule preparation equipment and preparation technology, its characterized in that, including main part (1), the inside of main part (1) is equipped with power unit (6), the top of power unit (6) is equipped with refines mechanism (5), the one end of refining mechanism (5) is equipped with mixing mechanism (2), mixing mechanism (2) and refine and be equipped with between mechanism (5) and separate mechanism (3), be connected with separating mechanism (4) on separate mechanism (3).
2. The device and the process for preparing the Paracetamol, Cabernet Sambucus and chlorphenamine maleate capsules according to claim 1, wherein the device and the process are as follows: mixing mechanism (2) is including blending tank (21), the one end of main part (1) is equipped with blending tank (21), the top of blending tank (21) is equipped with first motor (23), fixedly connected with second mount (28) between first motor (23) and blending tank (21), first mount (22) of fixedly connected with between blending tank (21) and main part (1).
3. The device and the process for preparing the Paracetamol, Cabernet Sambucus and chlorphenamine maleate capsules according to claim 2, wherein the device and the process are as follows: the bottom fixedly connected with of first motor (23) first pivot (24), middle part fixedly connected with division board (25) of first pivot (24), the top of division board (25) is equipped with stirring frame (26), the first pivot (24) of stirring frame (26) fixed connection, the bottom welding of first pivot (24) has flight (27).
4. The device and the process for preparing the Paracetamol, Cabernet Sambucus and chlorphenamine maleate capsules according to claim 3, wherein the device and the process are as follows: separating mechanism (3) are including separator tube (31), the bottom intercommunication of blending tank (21) has separator tube (31), separator tube (31) internally mounted has second motor (32), the one end fixedly connected with second pivot (33) of second motor (32).
5. The device and the process for preparing the Paracetamol, Cabernet Sambucus and chlorphenamine maleate capsules according to claim 4, wherein the device and the process for preparing the Paracetamol, Cabernet Sambucus and chlorphenamine maleate capsules are characterized in that: be equipped with two cutting pieces (34) on second pivot (33), one of them cutting piece (34) are rotated and are connected first pivot (33), and another one cutting piece (34) are rotated and are connected second pivot (33), first gear of fixedly connected with (35), two on cutting piece (34) the meshing has second gear (36) between first gear (35).
6. The device and the process for preparing the Paracetamol, Cabernet Sambucus and chlorphenamine maleate capsules according to claim 5, wherein the device and the process are as follows: separating mechanism (4) are equipped with storage cylinder (41) including storage cylinder (41), the top of separator tube (31), the bottom intercommunication of storage cylinder (41) has dusting pipe (47), dusting pipe's (47) bottom extends to the inside of separator tube (31), the inside sliding connection of storage cylinder (41) has first slider (42), logical groove (43) have been seted up at the middle part of first slider (42).
7. The device and the process for preparing the Paracetamol, Cabernet Sambucus and chlorphenamine maleate capsules according to claim 6, wherein the device and the process for preparing the Paracetamol, Cabernet Sambucus and chlorphenamine maleate capsules are characterized in that: the top of first slider (42) is contradicted and is had spring (45), be connected with sleeve pipe (46) between storage cylinder (41) and first slider (42), the bottom of dusting pipe (47) is equipped with sieve (48), sieve (48) fixed connection is on the inner wall of separator tube (31), the bottom of sieve (48) is equipped with collects box (49), it connects separator tube (31) to collect box (49) can be dismantled.
8. The device and the process for preparing the Paracetamol, Cabernet Sambucus and chlorphenamine maleate capsules according to claim 1, wherein the device and the process are as follows: the refining mechanism (5) comprises a roller (51), the roller (51) is arranged at the top end of the main body (1), two barrel hoops (52) are welded on the outer side of the roller (51), a refining groove (53) is arranged in the roller (51), and a plurality of detection plates (54) are welded on the inner wall of the refining groove (53).
9. The device and the process for preparing the Paracetamol, Cabernet Sambucus and chlorphenamine maleate capsules according to claim 8, wherein the device and the process are as follows: power unit (6) include third pivot (61), the inside fixedly connected with of main part (1) is the second, third pivot (61), the inside sliding connection of main part (1) has second slider (67), fixedly connected with stopper (68) on second slider (67), the inside of main part (1) is equipped with places board (64), place board (64) rotate and connect third pivot (61), place board (64) sliding connection stopper (68), the bottom of second slider (67) is rotated and is connected with telescopic link (69), the inner wall of connecting main part (1) is rotated to the bottom of telescopic link (69).
10. The device and the process for preparing the Paracetamol, Cabernet Sambucus and chlorphenamine maleate capsules according to claim 9, wherein the device and the process for preparing the Paracetamol, Cabernet Sambucus and chlorphenamine maleate capsules are characterized in that: fixedly connected with fourth pivot (62) on second slider (67), rotate respectively on fourth pivot (62) and third pivot (61) and be connected with two support frames (63), it is connected with contact wheel (66) to rotate on support frame (63), contact wheel (66) roll connection barrel hoop (52), two fixedly connected with fifth pivot (69b) between contact wheel (66), install third motor (65) on place board (64), fixedly connected with runner (69c), two respectively on third motor (65) and fifth pivot (69b) the winding has connecting band (69a) between runner (69 c).
S1: when the main body 1 is used for preparing medicines, the mixing mechanism 2, the separating mechanism 3 and the power mechanism 6 are started in sequence, and meanwhile, enough medicine materials are added into the separating mechanism 4 to finish preparation work;
s2: then, raw medicinal materials are sequentially added into the mixing mechanism 2, a plurality of medicinal materials are fully stirred, then the medicinal materials enter the separation mechanism 3 for cutting and thinning, and the separation mechanism 4 is used for scattering medicinal powder which avoids bonding;
s3: at last, the power mechanism 6 is started to drive the refining mechanism 5 to operate, particles of scattered medicine powder sequentially enter the refining mechanism 5, the refining mechanism 5 utilizes centrifugal force to roll pills, so that the profiles of the pills are more rounded, the passing performance of the pills is improved, the capsules are conveniently loaded at the later stage to be sealed, and when the materials need to be discharged, the angle part inside the power mechanism 6 is started to enable the refining mechanism 5 to be inclined at a certain angle, so that the discharging of the pills is quicker.
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