CN208482400U - A kind of efficient wet mixer-granulator of particulate species drug - Google Patents
A kind of efficient wet mixer-granulator of particulate species drug Download PDFInfo
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- CN208482400U CN208482400U CN201820544894.4U CN201820544894U CN208482400U CN 208482400 U CN208482400 U CN 208482400U CN 201820544894 U CN201820544894 U CN 201820544894U CN 208482400 U CN208482400 U CN 208482400U
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Abstract
The utility model discloses a kind of efficient wet mixer-granulators of particulate species drug, including transport platform, the both ends of transport platform are provided with drive shaft, the bottom of transport platform is fixed with supporting leg, the bottom end of supporting leg is fixed with support base, drying box and grain forming case are provided at the top of transport platform, drying box is internally provided with heating board, grain forming case is internally provided with grain forming plate, the bottom of grain forming plate is provided with grain forming hole, the side of grain forming plate is provided with stripper plate, the side of stripper plate is fixed with telescopic rod, gluey discharge nozzle is provided at the top of grain forming case, grain forming case is connected with secondary agitation case by gluey discharge nozzle, spice is mixed again, so the ingredient between drug can be sufficiently mixed, and then improve the quality for producing rear medicine particle.
Description
Technical field
The utility model relates to pharmaceutical equipment technical field, specially a kind of efficient wet mixing granulation of particulate species drug
Machine.
Background technique
Efficient wet mixing granulation function is fast and effeciently stirred dry medicinal powder, then produces the wet-milling grain of homogeneous,
Efficiently, quickly, homogeneous, the step that makes to mix and pelletize completes, can be improved compared with original stirring plus swing granulation mode
As many as four times of work efficiency, thus more traditional granulating process equipment has significant superiority, be to meet the ideal granulation of GMP standard to set
It is standby, it is suitable for the industries such as pharmacy, chemical industry, food, powder metallurgy, cosmetics, dyestuff, detergent.
But existing medicine granulating machine is mostly that can only process the drug of crushed into powder state, can not be incited somebody to action
The solid drugs not crushed are processed, it is therefore desirable to be spent additional time and be crushed solid-state drug, and existing device
Solid-state drug, which can only be processed, cannot process liquid medicine, to reduce the working efficiency of pharmacy, there are also be exactly existing device
Only once stirred in whipping process, therefore lead to produce that the drug ingedient come is uneven, so as to cause medicine particle at
Quality is bad.
So how to design a kind of efficient wet mixer-granulator of particulate species drug, become what we currently to be solved
Problem.
Utility model content
It is above-mentioned to solve the purpose of this utility model is to provide a kind of efficient wet mixer-granulator of particulate species drug
The low problem low with drug quality of working efficiency is proposed in background technique.
To achieve the above object, the utility model provides the following technical solutions: a kind of efficient wet of particulate species drug of is mixed
Granulator is closed, including transport platform, the both ends of the transport platform are provided with drive shaft, the bottom of the transport platform is fixed with support
Leg, the bottom end of the supporting leg are fixed with support base, and drying box and grain forming case, institute are provided at the top of the transport platform
The heating board that is internally provided with of drying box is stated, the grain forming case is internally provided with grain forming plate, the grain forming
The bottom of plate is provided with grain forming hole, and the side of the grain forming plate is provided with stripper plate, and the side of the stripper plate is solid
Surely there is telescopic rod, gluey discharge nozzle is provided at the top of the grain forming case, the grain forming case passes through gluey discharge nozzle
It is connected with secondary agitation case, detent box is installed at the top of the secondary agitation case, the secondary agitation case is internally provided with
Shaft is braked, the detent box is connected with swingle by braking shaft, and the outer surface of the swingle is fixed with stirring blade,
The side of the secondary agitation case is connected with solid-liquid mixing case by once stirring discharge port, and case is mixed in the solid-liquid
Top be provided with mixer cone, the side of the mixer cone is fixed with powder conveying plate and liquid discharge nozzle, the liquid
One end of discharge nozzle is connected with liquid medicine mixing tank, and liquid funnel is provided at the top of the liquid medicine mixing tank, described
Liquid medicine mixing tank is internally provided with engine shaft, and one end of the engine shaft is equipped with mixing shaft, described
It is fixed with hybrid blade on the outside of mixing shaft, the center position of the engine shaft is provided with engine, the engine
Side be provided with solid-state medicament disintegrating case, the other end of the engine shaft is connected with connection shaft and crushing rotary drum, institute
The side for stating solid-state medicament disintegrating case is provided with powder discharge port, and solid-state leakage is provided at the top of the solid-state medicament disintegrating case
Bucket, the bottom that case is mixed in the liquid medicine mixing tank, solid-state medicament disintegrating case and solid-liquid are provided with partition.
Further, the support base is provided with multiple, and the support base is closely welded with supporting leg.
Further, the heating board is process by quartz material, and the heating board is fitted closely in drying box
On inner wall.
Further, the telescopic rod is composed of two sections of support rods, and is flexibly connected between the support rod of both ends.
Further, the liquid discharge nozzle is horizontal by 45 degree of angles, and the liquid discharge nozzle is through setting
In the side of liquid medicine mixing tank.
Further, the crushing rotary drum is in " cylinder ", and the outer surface of the crushing rotary drum is provided with multiple sawtooth
Particle.
Compared with prior art, the utility model has the beneficial effects that the efficient wet mixing granulation of this kind of granule medicament
Machine improves and increases on the basis of original granulator, this kind of device is provided with solid-state medicament disintegrating machine and liquid medicine
Mixing tank, when work, staff only needs for blocky drug to be put into solid-state medicament disintegrating case by solid-state funnel, while work
Make personnel and pour into pure water or liquid medicine in liquid medicine mixing tank by liquid funnel, engine band passes through hair at this time
Motivation shaft drives connection shaft rotation, and then connection shaft will drive crushing rotary drum and run at high speed, when solid medicine touches
When sawtooth particle on crushing rotary drum, since the sawtooth particle on outer surface of cylinder can squeeze solid medicine moment, excessively squeeze
The result of pressure is exactly that solid fragmentation is become powdered, then enters solid-liquid mixing by powder discharge port and powder conveying plate
In agitator tank, while engine shaft drives mixing shaft to run at high speed, and then mixes shaft and hybrid blade is driven to run at high speed,
It advances between each ingredient of liquid medicine of liquid medicine mixing tank and highly mixes, carry out basis for next process, then
The liquid medicine mixed enters solid-liquid by liquid discharge nozzle and is mixed in case, and such work process not only saves
In addition time and manpower is spent to go to crush the time of solid-state drug, additionally it is possible to which solid-liquid drug is processed together, therefore is improved
The working efficiency of device, this kind of device are provided with solid-liquid and case and secondary agitation case are mixed, when smashed powder pharmaceutical and
When the liquid medicine mixed enters solid-liquid mixing case by mixer cone, case is mixed in solid-liquid can be tentatively by solid-liquid
Drug is tentatively mixed, but is only once stirred it is possible that solid-liquid mixes non-uniform phenomenon, therefore this kind of device
It is provided with secondary agitation case, enters secondary agitation case by once stirring tapping channel when case is mixed from solid-liquid in stirring material
When interior, brake can drive swingle high speed rotation by braking shaft, and subsequent swingle will drive stirring blade and carry out high speed
Rotation is stirred, and the material that will go into secondary agitation case carries out secondary agitation, spice is mixed again, so drug
Between ingredient can be sufficiently mixed, and then improve the quality for producing rear medicine particle.
Detailed description of the invention
Fig. 1 is the overall structure diagram of the utility model;
Fig. 2 is the drying box and grain forming case the schematic diagram of the section structure of the utility model;
Fig. 3 is the secondary agitation case the schematic diagram of the section structure of the utility model;
Fig. 4 is the liquid medicine mixing tank the schematic diagram of the section structure of the utility model;
Fig. 5 is the solid-state medicament disintegrating case the schematic diagram of the section structure of the utility model.
In figure: 1, support base, 2, supporting leg, 3, transport platform, 4, drive shaft, 5, finished product discharge port, 6, drying box, 601,
Heating board, 7, grain forming case, 701, grain forming plate, 702, grain forming hole, 703, telescopic rod, 704, stripper plate, 8, glue
Shape discharge nozzle, 9, secondary agitation case, 901, braking shaft, 902, swingle, 903, stirring blade, 10, detent box, 11, primary
Stir tapping channel, 12, solid-liquid mixing case, 13, mixer cone, 14, powder conveying plate, 15, liquid discharge nozzle, 16, hair
Motivation, 17, liquid funnel, 18, liquid medicine mixing tank, 1801, mixing shaft, 1802, hybrid blade, 19, solid-state funnel,
20, solid-state medicament disintegrating case, 2001, connection shaft, 2002, engine shaft, 2003, crushing rotary drum, 2004, powder discharging
Mouthful, 21, partition.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole
Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work
Every other embodiment obtained, fall within the protection scope of the utility model.
Fig. 1-5 is please referred to, the utility model provides a kind of technical solution: a kind of efficient wet mixing system of particulate species drug
Grain machine, including support base 1, supporting leg 2, transport platform 3, drive shaft 4, finished product discharge port 5, drying box 6, heating board 601, particle
Shaping box 7, grain forming plate 701, grain forming hole 702, telescopic rod 703, stripper plate 704, gluey discharge nozzle 8, secondary agitation
Case 9, braking shaft 901, swingle 902, stirring blade 903, detent box 10, primary stirring tapping channel 11, solid-liquid mixing are stirred
Mix case 12, mixer cone 13, powder conveying plate 14, liquid discharge nozzle 15, engine 16, liquid funnel 17, liquid medicine mixing
Case 18, hybrid blade 1802, solid-state funnel 19, solid-state medicament disintegrating case 20, connection shaft 2001, starts at mixing shaft 1801
Machine shaft 2002, crushing rotary drum 2003, powder discharge port 2004 and partition 21, the both ends of transport platform 3 are provided with drive shaft 4, defeated
Send the bottom of platform 3 to be fixed with supporting leg 2, the bottom end of supporting leg 2 is fixed with support base 1, support base 1 be provided with it is multiple, and
Support base 1 and supporting leg 2 closely weld, and then provide a stable environment and work to device, the top setting of transport platform 3
Have a drying box 6 and grain forming case 7, drying box 6 is internally provided with heating board 601, heating board 601 processed by quartz material and
At, and heating board 601 is fitted closely on the inner wall of drying box 6, and then medicine particle after molding is carried out drying plastotype,
Grain shaping box 7 is internally provided with grain forming plate 701, and the bottom of grain forming plate 701 is provided with grain forming hole 702,
The side of grain profiled sheeting 701 is provided with stripper plate 704, and the side of stripper plate 704 is fixed with telescopic rod 703, and telescopic rod 703 is by two
Section support rod is composed, and is flexibly connected between the support rod of both ends, and then stripper plate 704 is pushed to carry out extruding colloidal drug,
The top of grain forming case 7 is provided with gluey discharge nozzle 8, and grain forming case 7 passes through gluey discharge nozzle 8 and is connected with secondary agitation case
9, the top of secondary agitation case 9 is equipped with detent box 10, and secondary agitation case 9 is internally provided with braking shaft 901, detent box 10
It is connected with swingle 902 by braking shaft 901, the outer surface of swingle 902 is fixed with stirring blade 903, secondary agitation case 9
Side by once stirring discharge port 11 be connected with solid-liquid be mixed case 12, solid-liquid be mixed case 12 top be provided with
Mixer cone 13, the side of mixer cone 13 are fixed with powder conveying plate 14 and liquid discharge nozzle 15, liquid discharge nozzle 15 and water
Plane is in 45 degree of angles, and liquid discharge nozzle 15 is disposed through the side of liquid medicine mixing tank 18, and then utilizes gravity
Liquid medicine is flowed into solid-liquid and is mixed in case 12 by potential energy, and one end of liquid discharge nozzle 15 is connected with liquid medicine mixing tank
18, the top of liquid medicine mixing tank 18 is provided with liquid funnel 17, and liquid medicine mixing tank 18 is internally provided with engine
Shaft 2002, one end of engine shaft 2002 are equipped with mixing shaft 1801, and the outside of mixing shaft 1801 is fixed with mixing
Blade 1802, the center position of engine shaft 2002 are provided with engine 16, and the side of engine 16 is provided with solid-state drug
Crush box 20, the other end of engine shaft 2002 are connected with connection shaft 2001 and crushing rotary drum 2003, crushing rotary drum 2003
The outer surface of " cylinder ", and crushing rotary drum 2003 is provided with multiple sawtooth particles, and then by solid-state medicament disintegrating at powder
Shape is conducive to next process, and the side of solid-state medicament disintegrating case 20 is provided with powder discharge port 2004, solid-state medicament disintegrating case 20
Top be provided with solid-state funnel 19, case 12 is mixed in liquid medicine mixing tank 18, solid-state medicament disintegrating case 20 and solid-liquid
Bottom is provided with partition 21.
Working principle: firstly, whether each component capabilities of staff's check device are normal, if finding some component capabilities not
When normal, it should repair in time or with changing, after each component capabilities of device to be checked are normal, device is placed in specified work
Make place and open power switch, subsequent staff only needs blocky drug being put into solid-state drug powder by solid-state funnel 19
In broken case 20, personnel are worked at the same time by pure water or liquid medicine, liquid medicine mixing tank 18 is poured by liquid funnel 17
Interior, for engine 16 with driving connection shaft 2001 to rotate by engine shaft 2002, being then connected to shaft 2001 can band at this time
Dynamic crushing rotary drum 2003 runs at high speed, when solid medicine touches the sawtooth particle on crushing rotary drum 2003, due to roller outside
Sawtooth particle on surface can squeeze solid medicine moment, and the result of excessive compression is exactly that solid fragmentation is become powdered,
Then enter solid-liquid by powder discharge port 2004 and powder conveying plate 14 to be mixed in case 12, while engine shaft 2002
It drives mixing shaft 1801 to run at high speed, then mixes shaft 1801 and hybrid blade 1802 is driven to run at high speed, will go into liquid
It is highly mixed between each ingredient of liquid medicine of state drug mixing tank 18, carries out basis for next process, then mixed
Liquid medicine enters solid-liquid by liquid discharge nozzle 15 and is mixed in case 12, when smashed powder pharmaceutical and mixes
When liquid medicine enters solid-liquid mixing case 12 by mixer cone 13, case 12 is mixed in solid-liquid can be tentatively by solid-liquid medicine
Product are tentatively mixed, but are only once stirred it is possible that solid-liquid mixes non-uniform phenomenon, therefore this kind of device is set
It is equipped with secondary agitation case 9, secondary stir is entered by once stirring tapping channel 11 when case 12 is mixed from solid-liquid in stirring material
When mixing in case 9, brake 10 can drive 902 high speed rotation of swingle by braking shaft 901, and subsequent swingle 902 will drive
Stirring blade 903 carries out high speed rotation and is stirred, and the material that will go into secondary agitation case carries out secondary agitation, finally, glue
Shape drug passes through gluey discharge nozzle 8 and enters in grain forming case 7, and the telescopic rod 703 in grain forming case 7 pushes stripper plate 704
Gluey drug is squeezed, gluey drug can become particle from the grain forming hole 702 of 701 bottom of grain forming plate and go out at this time
Come, side drying box 6 is then entered by transport platform 3, heating board 601, which can give off heat, is dried modeling for medicine particle
Shape, last staff collect finished product from finished product discharge port 5.
While there has been shown and described that the embodiments of the present invention, for the ordinary skill in the art,
It is understood that these embodiments can be carried out with a variety of variations in the case where not departing from the principles of the present invention and spirit, repaired
Change, replacement and variant, the scope of the utility model is defined by the appended claims and the equivalents thereof.
Claims (6)
1. a kind of efficient wet mixer-granulator of particulate species drug, including transport platform (3), it is characterised in that: the transport platform
(3) both ends are provided with drive shaft (4), and the bottom of the transport platform (3) is fixed with supporting leg (2), the bottom of the supporting leg (2)
End is fixed with support base (1), and drying box (6) and grain forming case (7) are provided at the top of the transport platform (3), described dry
Dry case (6) is internally provided with heating board (601), and the grain forming case (7) is internally provided with grain forming plate (701),
The bottom of the grain forming plate (701) is provided with grain forming hole (702), the side setting of the grain forming plate (701)
Have stripper plate (704), the side of the stripper plate (704) is fixed with telescopic rod (703), the top of the grain forming case (7)
It is provided with gluey discharge nozzle (8), the grain forming case (7) passes through gluey discharge nozzle (8) and is connected with secondary agitation case (9), institute
It states and is equipped at the top of secondary agitation case (9) detent box (10), the secondary agitation case (9) is internally provided with braking shaft
(901), the detent box (10) is connected with swingle (902) by braking shaft (901), the appearance of the swingle (902)
Face is fixed with stirring blade (903), and the side of the secondary agitation case (9) is connected with solid-liquid by once stirring discharge port (11)
It is mixed case (12), the solid-liquid is mixed at the top of case (12) and is provided with mixer cone (13), the mixer cone
(13) side is fixed with powder conveying plate (14) and liquid discharge nozzle (15), and one end of the liquid discharge nozzle (15) is connected with
Liquid medicine mixing tank (18) is provided with liquid funnel (17) at the top of the liquid medicine mixing tank (18), the liquid medicine
Product mixing tank (18) is internally provided with engine shaft (2002), and one end of the engine shaft (2002) is equipped with mixing
Shaft (1801) is fixed with hybrid blade (1802) on the outside of the mixing shaft (1801), the engine shaft (2002)
Center position be provided with engine (16), the side of the engine (16) is provided with solid-state medicament disintegrating case (20), described
The other end of engine shaft (2002) is connected with connection shaft (2001) and crushing rotary drum (2003), the solid-state medicament disintegrating
The side of case (20) is provided with powder discharge port (2004), is provided with solid-state funnel at the top of the solid-state medicament disintegrating case (20)
(19), the bottom that case (12) are mixed in the liquid medicine mixing tank (18), solid-state medicament disintegrating case (20) and solid-liquid is all provided with
It is equipped with partition (21).
2. a kind of efficient wet mixer-granulator of particulate species drug according to claim 1, it is characterised in that: the branch
Support pedestal (1) is provided with multiple, and the support base (1) and supporting leg (2) are closely welded.
3. a kind of efficient wet mixer-granulator of particulate species drug according to claim 1, it is characterised in that: the hair
Hot plate (601) is process by quartz material, and the heating board (601) is fitted closely on the inner wall of drying box (6).
4. a kind of efficient wet mixer-granulator of particulate species drug according to claim 1, it is characterised in that: described to stretch
Contracting bar (703) is composed of two sections of support rods, and is flexibly connected between the support rod of both ends.
5. a kind of efficient wet mixer-granulator of particulate species drug according to claim 1, it is characterised in that: the liquid
State discharge nozzle (15) is horizontal by 45 degree of angles, and the liquid discharge nozzle (15) is disposed through liquid medicine mixing tank
(18) side.
6. a kind of efficient wet mixer-granulator of particulate species drug according to claim 1, it is characterised in that: the powder
Broken roller (2003) is in " cylinder ", and the outer surface of the crushing rotary drum (2003) is provided with multiple sawtooth particles.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201820544894.4U CN208482400U (en) | 2018-04-17 | 2018-04-17 | A kind of efficient wet mixer-granulator of particulate species drug |
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CN201820544894.4U CN208482400U (en) | 2018-04-17 | 2018-04-17 | A kind of efficient wet mixer-granulator of particulate species drug |
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CN208482400U true CN208482400U (en) | 2019-02-12 |
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CN201820544894.4U Expired - Fee Related CN208482400U (en) | 2018-04-17 | 2018-04-17 | A kind of efficient wet mixer-granulator of particulate species drug |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108311062A (en) * | 2018-04-17 | 2018-07-24 | 江西铜鼓仁和制药有限公司 | A kind of efficient wet mixing granulation system of particulate species drug |
CN111117716A (en) * | 2020-01-19 | 2020-05-08 | 福建省锅炉压力容器检验研究院 | Sludge waste bacteria stick derived solid fuel and preparation method thereof |
CN114129446A (en) * | 2021-11-19 | 2022-03-04 | 德州德药制药有限公司 | Equipment and process for preparing Paracetamol, Caffein and chlorphenamine maleate capsules |
-
2018
- 2018-04-17 CN CN201820544894.4U patent/CN208482400U/en not_active Expired - Fee Related
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108311062A (en) * | 2018-04-17 | 2018-07-24 | 江西铜鼓仁和制药有限公司 | A kind of efficient wet mixing granulation system of particulate species drug |
CN111117716A (en) * | 2020-01-19 | 2020-05-08 | 福建省锅炉压力容器检验研究院 | Sludge waste bacteria stick derived solid fuel and preparation method thereof |
CN114129446A (en) * | 2021-11-19 | 2022-03-04 | 德州德药制药有限公司 | Equipment and process for preparing Paracetamol, Caffein and chlorphenamine maleate capsules |
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Legal Events
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GR01 | Patent grant | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20190212 Termination date: 20200417 |