CN114062661B - Sample analyzer, sampling needle cleaning liquid path and cleaning method thereof - Google Patents
Sample analyzer, sampling needle cleaning liquid path and cleaning method thereof Download PDFInfo
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- CN114062661B CN114062661B CN202010752829.2A CN202010752829A CN114062661B CN 114062661 B CN114062661 B CN 114062661B CN 202010752829 A CN202010752829 A CN 202010752829A CN 114062661 B CN114062661 B CN 114062661B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B9/00—Cleaning hollow articles by methods or apparatus specially adapted thereto
- B08B9/02—Cleaning pipes or tubes or systems of pipes or tubes
- B08B9/023—Cleaning the external surface
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B9/00—Cleaning hollow articles by methods or apparatus specially adapted thereto
- B08B9/02—Cleaning pipes or tubes or systems of pipes or tubes
- B08B9/027—Cleaning the internal surfaces; Removal of blockages
- B08B9/032—Cleaning the internal surfaces; Removal of blockages by the mechanical action of a moving fluid, e.g. by flushing
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Abstract
The invention provides a sample analyzer, a sampling needle cleaning liquid path and a cleaning method thereof, wherein the cleaning liquid path comprises a sampling needle, a cleaning swab, a first waste liquid tank and a gas source for providing positive pressure and negative pressure; the cleaning swab is used for matching with the inner wall and the outer wall of the cleaning sampling needle and is provided with a liquid inlet end and a liquid outlet end; first waste liquid jar is connected and is connected with the air supply with the play liquid end of washing swab, and first waste liquid jar forms the negative pressure jar in order to collect the washing waste liquid when wasing through the negative pressure effect of air supply, and first waste liquid jar forms the malleation jar in order to be used for discharging the waste liquid through the malleation effect of air supply. According to the sample analyzer, the sampling needle cleaning liquid path and the cleaning method thereof, the waste liquid tank for collecting the cleaning waste liquid is used for establishing the negative pressure, a vacuum pump special for providing the negative pressure is omitted, the element cost is saved, and the occupied space volume in the instrument is reduced.
Description
Technical Field
The invention relates to the technical field of medical detection and analysis, in particular to a sample analyzer, a sampling needle cleaning liquid path and a cleaning method thereof.
Background
Referring to fig. 1, the waste liquid generated by the conventional sample analyzer when cleaning the inner wall or the outer wall of the sampling needle is collected by establishing a negative pressure by using an independent vacuum pump 5, which generally comprises the following steps:
the diluent of washing usefulness gets into from the inlet end 2.1 that washs swab 2, through the special internal cavity structure that washs swab 2 and provide, under the effect of liquid stream, washs the outer wall of sampling needle 1, then the waste liquid that washs the production flows out from the play liquid end 2.2 that washs swab 2, through two-way valve 4 under the negative pressure effect that vacuum pump 5 established, gets rid of the waste liquid, accomplishes whole cleaning process.
However, the existing sampling needle cleaning liquid path has the following disadvantages:
1. a vacuum pump 5 specially providing negative pressure is required, and the vacuum pump 5 needs to occupy a certain space inside the sample analyzer;
2. because the sampling needle 1 needs to suck samples frequently, so that a lot of debris exist in the waste liquid, the existing mode needs a filter 3 for filtering and collecting impurity debris in the waste liquid and replacing the impurity debris regularly;
3. even if one filter 3 is reserved exclusively, since the waste liquid is to be in direct contact with the inside of the electromagnetic two-way valve 4 and the vacuum pump 5, long-term use has an influence on the life of the two-way valve 4 and the vacuum pump 5.
Disclosure of Invention
The invention provides a sample analyzer, a sampling needle cleaning liquid path and a cleaning method thereof, and aims to solve the technical problem that a vacuum pump specially providing negative pressure occupies the internal space of the analyzer in the prior art.
In order to solve the technical problems, the invention adopts a technical scheme that: providing a sampling needle cleaning liquid path, wherein the cleaning liquid path comprises a sampling needle, a cleaning swab, a first waste liquid tank and a gas source for providing positive pressure and negative pressure;
the cleaning swab is used for cleaning the inner wall and the outer wall of the sampling needle in a matched manner, and is provided with a liquid inlet end and a liquid outlet end;
the first waste liquid tank is connected with the liquid outlet end of the cleaning swab and connected with the air source, the first waste liquid tank forms a negative pressure tank through the negative pressure effect of the air source so as to collect cleaning waste liquid during cleaning, and the first waste liquid tank forms a positive pressure tank through the positive pressure effect of the air source so as to discharge the waste liquid.
According to a specific embodiment of the present invention, the cleaning liquid path further includes a first liquid discharge pipe, a first pressure cut-off valve, and a first gate valve;
the first liquid discharge pipe connects the liquid outlet end of the cleaning swab with the first waste liquid tank;
the first pressure-break valve is arranged on the path of the first liquid discharge pipe;
the air source is connected with the first pressure break valve through the first gate valve, and the first gate valve is used for realizing positive pressure and air-to-air switching to switch the stop state and the conduction state of the first pressure break valve.
According to a specific embodiment of the present invention, the cleaning liquid path further includes a second gate valve;
the gas source is connected with the first waste liquid tank through the second selective valve, and the second selective valve is used for realizing positive pressure and negative pressure switching so as to switch a positive pressure state and a negative pressure state in the first waste liquid tank.
According to a specific embodiment of the present invention, the cleaning liquid path further includes a second waste liquid tank, the second waste liquid tank is connected to the liquid outlet end of the cleaning swab and connected to the gas source, the second waste liquid tank forms a negative pressure tank through a negative pressure effect of the gas source to collect the cleaning waste liquid during cleaning, and the second waste liquid tank forms a positive pressure tank through a positive pressure effect of the gas source to discharge the waste liquid.
According to a specific embodiment of the present invention, the cleaning liquid path further includes an impedance detection cell, the impedance detection cell includes a front cell and a rear cell which are communicated with each other through a micropore, the second waste liquid tank is connected to the rear cell, the second waste liquid tank forms a negative pressure tank through a negative pressure effect of the gas source to pump the sample liquid in the front cell to the rear cell through the micropore, and the second waste liquid tank forms a positive pressure tank through a positive pressure effect of the gas source to discharge the waste liquid.
According to a specific embodiment of the present invention, the cleaning liquid path further includes a common pipeline, a second liquid discharge pipe, a second pressure-cut valve, and a third gate valve;
the second liquid discharge pipe connects the liquid outlet end of the cleaning swab with the second waste liquid tank, wherein one end of the common pipeline is connected with the liquid outlet end of the cleaning swab, and the other end of the common pipeline is connected with the first liquid discharge pipe and the second liquid discharge pipe to form a Y-shaped liquid path;
the second pressure-breaking valve is arranged on the path of the second liquid discharge pipe;
the air source is connected with the second pressure-break valve through the third selective valve, and the third selective valve is used for realizing positive pressure and air-to-air switching to switch the cut-off state and the conduction state of the second pressure-break valve.
According to a specific embodiment of the present invention, the cleaning liquid path further includes a fourth gate valve and a fifth gate valve;
the gas source is connected with the second waste liquid tank sequentially through the fourth selective valve and the fifth selective valve, and the fourth selective valve and the fifth selective valve are used for realizing positive pressure and negative pressure switching so as to switch a positive pressure state and a negative pressure state in the second waste liquid tank.
In order to solve the technical problem, the invention adopts another technical scheme that: provided is a sampling needle cleaning method, comprising the following steps:
establishing negative pressure in the first waste liquid tank through the negative pressure action of the air source to form a negative pressure tank;
collecting cleaning waste liquid when the sampling needle is cleaned by utilizing the negative pressure in the first waste liquid tank;
establishing positive pressure in the first waste liquid tank by the positive pressure action of the gas source to form a positive pressure tank for discharging the waste liquid.
According to a specific embodiment of the invention, a negative pressure is established in the second waste liquid tank by the negative pressure action of the air source to form a negative pressure tank;
collecting the cleaning waste liquid when the sampling needle is cleaned by utilizing the negative pressure in the second waste liquid tank and/or providing the negative pressure required by the detection of an impedance detection method;
establishing a positive pressure in the second waste liquid tank by the positive pressure action of the gas source to form a positive pressure tank for discharging the waste liquid;
wherein a first press-to-break valve and a second press-to-break valve are respectively provided on paths between the first waste liquid tank and the second waste liquid tank and the needle, and the first waste liquid tank and the second waste liquid tank are alternately used by alternately opening the first press-to-break valve and the second press-to-break valve.
In order to solve the technical problem, the invention adopts another technical scheme that: a sample analyzer is provided that includes the aforementioned sampling needle cleaning fluid circuit.
The beneficial effects of the invention are: different from the situation of the prior art, in the sample analyzer, the sampling needle cleaning liquid path and the cleaning method thereof, the waste liquid tank for collecting the cleaning waste liquid is used for establishing the negative pressure, so that a vacuum pump special for providing the negative pressure is omitted, the element cost is saved, and the occupied space and volume in the instrument are reduced.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the description of the embodiments will be briefly introduced below, it is obvious that the drawings in the following description are only some embodiments of the invention, and other drawings can be obtained by those skilled in the art without inventive efforts, wherein:
FIG. 1 is a schematic diagram of a prior art sampling needle cleaning fluid path;
fig. 2 is a schematic diagram of a liquid path principle of a sampling needle cleaning liquid path provided in an embodiment of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without making any creative effort based on the embodiments in the present invention, belong to the protection scope of the present invention.
It should be noted that, if directional indications (such as upper, lower, left, right, front, rear, 8230; \8230;) are involved in the embodiment of the present invention, the directional indications are only used to explain the relative positional relationship between the components in a specific posture (as shown in the figure), the motion situation, etc., and if the specific posture is changed, the directional indications are correspondingly changed.
In addition, if there is a description of "first", "second", etc. in an embodiment of the present invention, the description of "first", "second", etc. is for descriptive purposes only and is not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In addition, technical solutions between the embodiments may be combined with each other, but must be based on the realization of the technical solutions by a person skilled in the art, and when the technical solutions are contradictory to each other or cannot be realized, such a combination should not be considered to exist, and is not within the protection scope of the present invention.
Referring to fig. 2, an embodiment of the present invention provides a cleaning solution path, which includes a sampling needle 10, a cleaning swab 20, a first waste liquid tank 31, and a gas source 40 for providing positive pressure and negative pressure.
The cleaning swab 20 is used for matching and cleaning the inner wall and the outer wall of the sampling needle 10, and the cleaning swab 20 is provided with a liquid inlet end 21 and a liquid outlet end 22. The structure and operation of the cleaning swab 20 are not related to the invention, and reference is made to the prior art, which is not described herein.
The first waste liquid tank 31 is connected with the liquid outlet end 22 of the cleaning swab 20 and is connected with the gas source 40, the first waste liquid tank 31 forms a negative pressure tank through the negative pressure effect of the gas source 40 to collect the cleaning waste liquid during cleaning, and the first waste liquid tank 31 (when the waste liquid reaches a preset volume or each time the detection is finished) forms a positive pressure tank through the positive pressure effect of the gas source 40 to discharge the waste liquid.
Specifically, the cleaning liquid path further includes a first drain pipe 11, a first pressure-cutoff valve 51, a first selective valve 61, and a second selective valve 62.
The first drain tube 11 connects the liquid outlet end 22 of the cleaning swab 20 to the first waste liquid tank 31, and the first pressure cutoff valve 51 is provided on the path of the first drain tube 11.
The air source 40 is connected to the first pressure cut-off valve 51 through a first gate valve 61, and the first gate valve 61 is used for switching between positive pressure and air to switch between a cut-off state and a conducting state of the first pressure cut-off valve 51.
The gas source 40 is connected to the first waste liquid tank 31 through a second gate valve 62, and the second gate valve 62 is used to switch between positive pressure and negative pressure to switch between the positive pressure state and the negative pressure state in the first waste liquid tank 31.
Specifically, the first liquid discharge pipe 11 is in a cut-off state in a normal state, that is, the first selection valve 61 allows a positive pressure to be applied to the first pressure cutoff valve 51 in the normal state so that the first pressure cutoff valve 51 is in the cut-off state, when the sampling needle 10 needs to be cleaned, the positive pressure action disappears by switching the first selection valve 61 to the empty position, and the first pressure cutoff valve 51 is switched from the cut-off state to the conducting state under the action of its own spring force so as to allow the waste liquid to be collected into the first waste liquid tank 31 under the action of the negative pressure established by the first waste liquid tank 31 to complete the cleaning process.
After the waste liquid in the first waste liquid tank 31 reaches a certain level, the second gating valve 62 is switched, so that the negative pressure of the first waste liquid tank 31 is changed into positive pressure (for example, positive pressure of +70 KPA), and the waste liquid can be drained from the bottom of the first waste liquid tank 31 under the action of the positive pressure;
the first liquid discharge pipe 11 can be a Pharmed pipe, the service life of the first liquid discharge pipe is 30 times that of a common silicone tube, and the air tightness of the first liquid discharge pipe is 60 times; the size specification can be 3.2 internal diameters, 6.4 external diameters, and ordinary big and small particulate matters can pass through completely, do not have the stifled risk of dying. And the problem of chip blockage is not easy to occur by adopting a pressure-breaking valve, and the maintenance cost of the instrument is correspondingly reduced.
In this embodiment, the negative pressure is established by the first waste liquid tank 31 for collecting the cleaning waste liquid, so that a vacuum pump for specially providing the negative pressure is omitted, the component cost is saved, and the occupied space volume inside the sample analyzer is reduced.
With reference to fig. 2, another embodiment of the present invention provides a cleaning liquid path, which includes a sampling needle 10, a first liquid discharging pipe 11, a second liquid discharging pipe 12, a common pipe 13, a cleaning swab 20, a first waste liquid tank 31, a second waste liquid tank 32, an air source 40 for providing positive pressure and negative pressure, a first pressure stop valve 51, a second pressure stop valve 52, a first selection valve 61, a second selection valve 62, a third selection valve 63, a fourth selection valve 64, and a fifth selection valve 65.
Wherein, the cleaning swab 20 is used for matching and cleaning the inner wall and the outer wall of the sampling needle 10, and the cleaning swab 20 is provided with a liquid inlet end 21 and a liquid outlet end 22. The structure and operation of the cleaning swab 20 are not related to the invention, and reference is made to the prior art, which is not described herein.
The first waste liquid tank 31 is connected to the liquid outlet end 22 of the cleaning swab 20 and connected to the gas source 40, the first waste liquid tank 31 forms a negative pressure tank by the negative pressure of the gas source 40 to collect the cleaning waste liquid during cleaning, and the first waste liquid tank 31 forms a positive pressure tank by the positive pressure of the gas source 40 to discharge the cleaning waste liquid (when the cleaning waste liquid reaches a predetermined volume or each time the detection is finished).
The second waste liquid tank 32 is connected to the liquid outlet end 22 of the cleaning swab 20 and connected to the gas source 40, the second waste liquid tank 32 forms a negative pressure tank by the negative pressure effect of the gas source 40 to collect the cleaning waste liquid during cleaning, and the second waste liquid tank 32 forms a positive pressure tank by the positive pressure effect of the gas source 40 (when the waste liquid reaches a predetermined volume or each time the detection is finished) to discharge the waste liquid.
The first drain tube 11 connects the liquid outlet end 22 of the cleaning swab 20 to the first waste liquid tank 31, and the first pressure cutoff valve 51 is provided on the path of the first drain tube 11.
The second liquid discharge pipe 12 connects the liquid outlet end 22 of the cleaning swab 20 with the second waste liquid tank 32, and the second pressure-cutoff valve 52 is disposed on the path of the second liquid discharge pipe 12, wherein one end of the common pipe 13 is connected with the liquid outlet end 22 of the cleaning swab 20, and the other end of the common pipe 13 forms a Y-shaped liquid path connection with the first liquid discharge pipe 11 and the second liquid discharge pipe 12.
The air source 40 is connected to the first pressure cutoff valve 51 through a first gate valve 61, and the first gate valve 61 is used to realize positive pressure and air-to-air switching to switch the cutoff state and the conduction state of the first pressure cutoff valve 51.
The gas source 40 is connected to the first waste liquid tank 31 through a second gate valve 62, and the second gate valve 62 is used for switching between positive pressure and negative pressure to switch between a positive pressure state and a negative pressure state in the first waste liquid tank 31.
The air source 40 is connected with the second pressure break valve 52 through a third gate valve 63, and the third gate valve 63 is used for realizing positive pressure and air-to-air switching to switch the cut-off state and the conducting state of the second pressure break valve 52.
The gas source 40 is connected to the second waste liquid tank 32 sequentially through the fourth optional valve 64 and the fifth optional valve 65, and the fourth optional valve 64 and the fifth optional valve 65 are used for switching between positive pressure and negative pressure to switch between a positive pressure state and a negative pressure state in the second waste liquid tank 32.
In addition, the cleaning fluid path may further include an impedance detection tank 70 and a pressure sensor 71, the impedance detection tank 70 includes a front tank and a rear tank communicated through a micro hole, the second waste fluid tank 32 is connected with the rear tank, the second waste fluid tank 32 forms a negative pressure tank through a negative pressure effect of the gas source 40 so as to pump the sample fluid in the front tank to the rear tank through the micro hole for impedance counting detection in cooperation, and the positive pressure tank is formed through a positive pressure effect of the gas source 40 so as to discharge the waste fluid when the waste fluid of the second waste fluid tank 32 reaches a preset volume.
Specifically, before the second waste liquid tank 32 is matched with the impedance method counting detection, a required negative pressure is established through the gas source 40 (a pressure value in the second waste liquid tank 32 can be detected through the pressure sensor 71), then the fifth gating valve 65 is switched to a cut-off state to play a role in stabilizing pressure, namely, the influence of the gas source 40 on the pressure in the second waste liquid tank 32 is blocked, at the moment, the second waste liquid tank 32 forms an independent and stable negative pressure device, the impedance detection tank 70 is communicated with the second waste liquid tank 32 with the established negative pressure through a counting valve assembly, and a sample to be detected is pumped to the tank through micro air from a forebay under the negative pressure effect of the second waste liquid tank 32 to perform corresponding counting detection.
In this embodiment, there are two waste liquid tanks, and when counting detection is performed, the two waste liquid tanks can be switched to another one by selecting the first pressure cutoff valve 51 and the second pressure cutoff valve 52. That is, when the negative pressure of the second waste-liquid tank 32 is used for counting detection, the cleaning waste liquid is collected by the negative pressure of the first waste-liquid tank 31.
The project that present sample analysis appearance needs to detect is more, and speed requirement to the sample detection is also high, consequently needs frequent washing, through designing two way waste liquid jars, can be so that sample analysis appearance under high frequency cleaning state, through making a round trip to switch the washing route, builds pressure all the way in addition when abluent all the way, guarantees that the waste liquid jar in time provides sufficient negative pressure and uses in order to wash, guarantees sample detection speed.
The invention also provides a sample analyzer which comprises the sampling needle cleaning liquid path.
With continued reference to fig. 2, the present invention further provides a method for cleaning the sampling needle 10, the method comprising:
the negative pressure of the air source 40 is enabled to act on the first waste liquid tank 31 through the second selective valve 62 to establish a negative pressure to form a negative pressure tank;
collecting the cleaning waste liquid when the sampling needle 10 is cleaned by using the negative pressure in the first waste liquid tank 31 when the first pressure cutoff valve 51 is in a conducting state;
the positive pressure action of the gas source 40 is enabled to build up a positive pressure in the first waste liquid tank 31 through the second gate valve 62 (when the waste liquid of the first waste liquid tank 31 reaches a preset volume or each detection is finished) to form a positive pressure tank for discharging the waste liquid;
the negative pressure of the air source 40 is acted in the second waste liquid tank 32 through the fourth optional valve 64 and the fifth optional valve 65 to form a negative pressure tank;
the negative pressure in the second waste liquid tank 32 is used for collecting the cleaning waste liquid when the sampling needle 10 is cleaned and/or providing the negative pressure required by the impedance detection method for detection;
positive pressure is established in the second waste-liquid tank 32 (at the time when the waste liquid of the second waste-liquid tank 32 reaches a preset volume or at the end of each detection) by the positive pressure action of the gas source 40 to form a positive pressure tank for discharging the waste liquid.
Wherein, be provided with first pressure cut-off valve 51 and second pressure cut-off valve 52 on the route between first waste liquid jar 31 and second waste liquid jar 32 and the adoption needle respectively, through opening first pressure cut-off valve 51 and second pressure cut-off valve 52 and then alternate use first waste liquid jar 31 and second waste liquid jar 32 in turn and can guarantee that the waste liquid jar in time provides sufficient negative pressure and use for the washing, guarantee sample detection speed.
In summary, it is easily understood by those skilled in the art that, in the sample analyzer, the sampling needle cleaning solution path and the cleaning method thereof provided by the present invention, the waste solution tank for collecting the cleaning waste solution is used to establish the negative pressure, so that a vacuum pump for specially providing the negative pressure is omitted, the component cost is saved, the internal space volume occupation of the instrument is reduced, the problem of debris blockage is not easily caused by using the pressure-breaking valve, and the maintenance cost of the instrument is correspondingly reduced.
The above description is only an embodiment of the present invention, and is not intended to limit the scope of the present invention, and all equivalent structures or equivalent processes performed by the present invention or directly or indirectly applied to other related technical fields are included in the scope of the present invention.
Claims (5)
1. A sampling needle cleaning fluid way which is characterized in that:
the cleaning liquid path comprises a sampling needle, a cleaning swab, a first waste liquid tank and an air source for providing positive pressure and negative pressure;
the cleaning swab is used for cleaning the inner wall and the outer wall of the sampling needle in a matched manner, and is provided with a liquid inlet end and a liquid outlet end;
the first waste liquid tank is connected with the liquid outlet end of the cleaning swab and is connected with the gas source,
the first waste liquid tank forms a negative pressure tank through the negative pressure action of the gas source so as to collect cleaning waste liquid during cleaning, and the first waste liquid tank forms a positive pressure tank through the positive pressure action of the gas source so as to discharge the waste liquid;
the cleaning liquid path also comprises a first liquid discharge pipe, a first pressure break valve and a first selective valve;
the first liquid discharge pipe connects the liquid outlet end of the cleaning swab with the first waste liquid tank;
the first pressure-break valve is arranged on the path of the first liquid discharge pipe;
the air source is connected with the first pressure-break valve through the first gate valve, and the first gate valve is used for realizing positive pressure and air-to-air switching to switch the cut-off state and the conduction state of the first pressure-break valve;
the cleaning liquid path also comprises a second waste liquid tank, the second waste liquid tank is connected with the liquid outlet end of the cleaning swab and is connected with the gas source, the second waste liquid tank forms a negative pressure tank through the negative pressure action of the gas source so as to collect cleaning waste liquid during cleaning, and the second waste liquid tank forms a positive pressure tank through the positive pressure action of the gas source so as to discharge the waste liquid;
the cleaning liquid path also comprises a public pipeline, a second liquid discharge pipe, a second pressure-break valve and a third gating valve;
the second liquid discharge pipe connects the liquid outlet end of the cleaning swab with the second waste liquid tank, wherein one end of the common pipeline is connected with the liquid outlet end of the cleaning swab, and the other end of the common pipeline is connected with the first liquid discharge pipe and the second liquid discharge pipe to form a Y-shaped liquid path;
the second pressure-breaking valve is arranged on the path of the second liquid discharge pipe;
the air source is connected with the second pressure break valve through the third gate valve, and the third gate valve is used for realizing positive pressure and air-to-air switching so as to switch the stop state and the conduction state of the second pressure break valve;
the cleaning fluid path also comprises an impedance detection pool and a pressure sensor, the impedance detection pool comprises a front pool and a rear pool which are communicated through a micropore, the second waste fluid tank is connected with the rear pool, the pressure sensor is used for detecting the pressure value in the second waste fluid tank, and the second waste fluid tank forms a negative pressure tank through the negative pressure effect of the air source so as to pump the sample fluid in the front pool to the rear pool through the micropore; the cleaning liquid path also comprises a fourth selective valve and a fifth selective valve;
the gas source is connected with the second waste liquid tank sequentially through the fourth selective valve and the fifth selective valve, the fourth selective valve and the fifth selective valve are used for realizing positive pressure and negative pressure switching to switch a positive pressure state and a negative pressure state in the second waste liquid tank, and the fifth selective valve is switched to a stop state when the pressure sensor detects that the pressure value in the second waste liquid tank reaches the required negative pressure, so that the pressure stabilizing effect is achieved.
2. The sampling needle cleaning fluid circuit according to claim 1, characterized in that:
the cleaning liquid path also comprises a second gating valve;
the gas source is connected with the first waste liquid tank through the second selective valve, and the second selective valve is used for realizing positive pressure and negative pressure switching so as to switch a positive pressure state and a negative pressure state in the first waste liquid tank.
3. The sampling needle cleaning fluid circuit according to claim 1, characterized in that: the cleaning liquid path also comprises a fourth selective valve and a fifth selective valve;
the gas source is connected with the second waste liquid tank sequentially through the fourth selective valve and the fifth selective valve, and the fourth selective valve and the fifth selective valve are used for realizing positive pressure and negative pressure switching so as to switch a positive pressure state and a negative pressure state in the second waste liquid tank.
4. A method of cleaning a sampling needle, comprising:
establishing negative pressure in the first waste liquid tank through the negative pressure action of the air source to form a negative pressure tank;
collecting cleaning waste liquid when the sampling needle is cleaned by utilizing the negative pressure in the first waste liquid tank;
establishing a positive pressure within the first waste tank by positive pressure action of the gas source to form a positive pressure tank for discharging the waste liquid;
establishing negative pressure in the second waste liquid tank through the negative pressure action of the air source to form a negative pressure tank;
collecting the cleaning waste liquid when the sampling needle is cleaned by utilizing the negative pressure in the second waste liquid tank and/or providing the negative pressure required by the impedance detection method for detection;
establishing a positive pressure in the second waste liquid tank by the positive pressure action of the gas source to form a positive pressure tank for discharging the waste liquid;
wherein a first pressure cutoff valve and a second pressure cutoff valve are respectively arranged on paths between the first waste liquid tank and the sampling needle, and the first waste liquid tank and the second waste liquid tank are alternately used by alternately opening the first pressure cutoff valve and the second pressure cutoff valve; the gas source is connected with the second waste liquid tank sequentially through a fourth selective valve and a fifth selective valve, the fourth selective valve and the fifth selective valve are used for realizing positive pressure and negative pressure switching to switch a positive pressure state and a negative pressure state in the second waste liquid tank, and the fifth selective valve is switched to a stop state when a pressure sensor detects that a pressure value in the second waste liquid tank reaches a required negative pressure, so that a pressure stabilizing effect is achieved.
5. A sample analyzer, comprising: the sample analyzer includes the sampling needle cleaning fluid circuit of any of claims 1-3.
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| CN114778814A (en) * | 2022-06-13 | 2022-07-22 | 深圳市帝迈生物技术有限公司 | Waste liquid discharge system, sample analyzer and waste liquid discharge method |
| CN114798581B (en) * | 2022-06-28 | 2022-10-28 | 深圳市帝迈生物技术有限公司 | Cleaning device and cleaning method for sample analyzer |
| CN114798614B (en) * | 2022-06-28 | 2022-10-28 | 深圳市帝迈生物技术有限公司 | Cleaning device and cleaning method for sample analyzer and sample analyzer |
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| JPH0664155U (en) * | 1993-02-12 | 1994-09-09 | 東レ株式会社 | Waste liquid treatment device for analyzer |
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| CN110877040B (en) * | 2019-11-20 | 2021-07-20 | 香港大德昌龙生物科技有限公司 | Sample adding needle cleaning equipment, sample adding needle cleaning method and application |
| CN112403953B (en) * | 2020-10-28 | 2022-04-15 | 迈克医疗电子有限公司 | Method and apparatus for cleaning sampling needle assembly |
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