CN114051421A - 用于改善睡眠障碍性呼吸的系统和方法 - Google Patents
用于改善睡眠障碍性呼吸的系统和方法 Download PDFInfo
- Publication number
- CN114051421A CN114051421A CN202080048590.9A CN202080048590A CN114051421A CN 114051421 A CN114051421 A CN 114051421A CN 202080048590 A CN202080048590 A CN 202080048590A CN 114051421 A CN114051421 A CN 114051421A
- Authority
- CN
- China
- Prior art keywords
- neuromodulation
- stimulation
- sleep
- coil
- antenna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000007958 sleep Effects 0.000 title claims abstract description 68
- 230000029058 respiratory gaseous exchange Effects 0.000 title claims description 25
- 238000000034 method Methods 0.000 title description 16
- 230000004007 neuromodulation Effects 0.000 claims abstract description 50
- 230000000638 stimulation Effects 0.000 claims description 129
- 210000003205 muscle Anatomy 0.000 claims description 47
- 239000000758 substrate Substances 0.000 claims description 27
- 230000000694 effects Effects 0.000 claims description 24
- 210000001169 hypoglossal nerve Anatomy 0.000 claims description 24
- 230000008859 change Effects 0.000 claims description 20
- 239000000090 biomarker Substances 0.000 claims description 17
- 230000004044 response Effects 0.000 claims description 17
- 230000001256 tonic effect Effects 0.000 claims description 13
- 230000005672 electromagnetic field Effects 0.000 claims description 11
- 210000005036 nerve Anatomy 0.000 claims description 11
- 206010062519 Poor quality sleep Diseases 0.000 claims description 8
- 230000036385 rapid eye movement (rem) sleep Effects 0.000 claims description 7
- 230000005540 biological transmission Effects 0.000 claims description 5
- 230000001939 inductive effect Effects 0.000 claims description 5
- 238000012544 monitoring process Methods 0.000 claims description 5
- 230000003044 adaptive effect Effects 0.000 claims description 4
- 239000000835 fiber Substances 0.000 claims description 4
- 230000002990 hypoglossal effect Effects 0.000 claims description 2
- 230000008093 supporting effect Effects 0.000 claims description 2
- 230000001537 neural effect Effects 0.000 abstract description 7
- 230000003387 muscular Effects 0.000 abstract description 3
- 238000002567 electromyography Methods 0.000 description 55
- 238000002560 therapeutic procedure Methods 0.000 description 54
- 208000001797 obstructive sleep apnea Diseases 0.000 description 19
- 230000006854 communication Effects 0.000 description 15
- 238000004891 communication Methods 0.000 description 15
- 238000010276 construction Methods 0.000 description 12
- 230000008667 sleep stage Effects 0.000 description 10
- 239000010949 copper Substances 0.000 description 9
- 239000010410 layer Substances 0.000 description 9
- 210000003484 anatomy Anatomy 0.000 description 8
- 230000033001 locomotion Effects 0.000 description 8
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 7
- 239000004020 conductor Substances 0.000 description 7
- 230000008602 contraction Effects 0.000 description 7
- 229910052802 copper Inorganic materials 0.000 description 7
- 238000013461 design Methods 0.000 description 6
- 239000002184 metal Substances 0.000 description 6
- 229910052751 metal Inorganic materials 0.000 description 6
- 239000004642 Polyimide Substances 0.000 description 5
- 230000037007 arousal Effects 0.000 description 5
- 239000000560 biocompatible material Substances 0.000 description 5
- 230000002232 neuromuscular Effects 0.000 description 5
- 229920001721 polyimide Polymers 0.000 description 5
- 229920000642 polymer Polymers 0.000 description 5
- 230000001276 controlling effect Effects 0.000 description 4
- 230000007423 decrease Effects 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 230000006870 function Effects 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000005457 optimization Methods 0.000 description 4
- 230000003071 parasitic effect Effects 0.000 description 4
- 229920001296 polysiloxane Polymers 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- 238000012546 transfer Methods 0.000 description 4
- 239000004593 Epoxy Substances 0.000 description 3
- 238000013473 artificial intelligence Methods 0.000 description 3
- 239000003990 capacitor Substances 0.000 description 3
- 230000008878 coupling Effects 0.000 description 3
- 238000010168 coupling process Methods 0.000 description 3
- 238000005859 coupling reaction Methods 0.000 description 3
- 230000003247 decreasing effect Effects 0.000 description 3
- 230000005674 electromagnetic induction Effects 0.000 description 3
- 230000004424 eye movement Effects 0.000 description 3
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 3
- 229910052737 gold Inorganic materials 0.000 description 3
- 239000010931 gold Substances 0.000 description 3
- 239000007943 implant Substances 0.000 description 3
- 238000002513 implantation Methods 0.000 description 3
- 230000000737 periodic effect Effects 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 230000004936 stimulating effect Effects 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 230000007704 transition Effects 0.000 description 3
- 206010041235 Snoring Diseases 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000036760 body temperature Effects 0.000 description 2
- 230000000875 corresponding effect Effects 0.000 description 2
- 230000005684 electric field Effects 0.000 description 2
- 238000004070 electrodeposition Methods 0.000 description 2
- 230000001976 improved effect Effects 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 230000003274 myotonic effect Effects 0.000 description 2
- 230000008452 non REM sleep Effects 0.000 description 2
- 235000012771 pancakes Nutrition 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 201000002859 sleep apnea Diseases 0.000 description 2
- 230000003068 static effect Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 238000004448 titration Methods 0.000 description 2
- 238000004804 winding Methods 0.000 description 2
- BSFZSQRJGZHMMV-UHFFFAOYSA-N 1,2,3-trichloro-5-phenylbenzene Chemical compound ClC1=C(Cl)C(Cl)=CC(C=2C=CC=CC=2)=C1 BSFZSQRJGZHMMV-UHFFFAOYSA-N 0.000 description 1
- 208000019901 Anxiety disease Diseases 0.000 description 1
- 208000007590 Disorders of Excessive Somnolence Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 206010021143 Hypoxia Diseases 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 101001034843 Mus musculus Interferon-induced transmembrane protein 1 Proteins 0.000 description 1
- 206010028347 Muscle twitching Diseases 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 208000037656 Respiratory Sounds Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 206010041349 Somnolence Diseases 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 238000004873 anchoring Methods 0.000 description 1
- 230000036506 anxiety Effects 0.000 description 1
- 230000002567 autonomic effect Effects 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 230000007175 bidirectional communication Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 230000003920 cognitive function Effects 0.000 description 1
- 238000004883 computer application Methods 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000005553 drilling Methods 0.000 description 1
- 230000005670 electromagnetic radiation Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 230000002964 excitative effect Effects 0.000 description 1
- 210000000744 eyelid Anatomy 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 238000007667 floating Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 208000018875 hypoxemia Diseases 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 238000010329 laser etching Methods 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- LQBJWKCYZGMFEV-UHFFFAOYSA-N lead tin Chemical compound [Sn].[Pb] LQBJWKCYZGMFEV-UHFFFAOYSA-N 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 238000007747 plating Methods 0.000 description 1
- 238000010248 power generation Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000002106 pulse oximetry Methods 0.000 description 1
- 230000004461 rapid eye movement Effects 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 239000005060 rubber Substances 0.000 description 1
- 238000010079 rubber tapping Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 208000019116 sleep disease Diseases 0.000 description 1
- 208000022925 sleep disturbance Diseases 0.000 description 1
- 230000003860 sleep quality Effects 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 238000003856 thermoforming Methods 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 230000002618 waking effect Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36135—Control systems using physiological parameters
- A61N1/36139—Control systems using physiological parameters with automatic adjustment
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
- G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
- A61M21/02—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis for inducing sleep or relaxation, e.g. by direct nerve stimulation, hypnosis, analgesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0031—Implanted circuitry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4806—Sleep evaluation
- A61B5/4812—Detecting sleep stages or cycles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
- A61B5/7267—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems involving training the classification device
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
- A61N1/0548—Oral electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36078—Inducing or controlling sleep or relaxation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/3611—Respiration control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36146—Control systems specified by the stimulation parameters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37217—Means for communicating with stimulators characterised by the communication link, e.g. acoustic or tactile
- A61N1/37223—Circuits for electromagnetic coupling
- A61N1/37229—Shape or location of the implanted or external antenna
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T11/00—2D [Two Dimensional] image generation
- G06T11/60—Editing figures and text; Combining figures or text
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/70—Determining position or orientation of objects or cameras
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V10/00—Arrangements for image or video recognition or understanding
- G06V10/40—Extraction of image or video features
- G06V10/42—Global feature extraction by analysis of the whole pattern, e.g. using frequency domain transformations or autocorrelation
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V10/00—Arrangements for image or video recognition or understanding
- G06V10/40—Extraction of image or video features
- G06V10/60—Extraction of image or video features relating to illumination properties, e.g. using a reflectance or lighting model
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V20/00—Scenes; Scene-specific elements
- G06V20/10—Terrestrial scenes
- G06V20/13—Satellite images
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V20/00—Scenes; Scene-specific elements
- G06V20/10—Terrestrial scenes
- G06V20/176—Urban or other man-made structures
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/30—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0204—Operational features of power management
- A61B2560/0214—Operational features of power management of power generation or supply
- A61B2560/0219—Operational features of power management of power generation or supply of externally powered implanted units
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
- A61B5/1113—Local tracking of patients, e.g. in a hospital or private home
- A61B5/1114—Tracking parts of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
- A61B5/1116—Determining posture transitions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/389—Electromyography [EMG]
- A61B5/394—Electromyography [EMG] specially adapted for electroglottography or electropalatography
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/45—For evaluating or diagnosing the musculoskeletal system or teeth
- A61B5/4538—Evaluating a particular part of the muscoloskeletal system or a particular medical condition
- A61B5/4542—Evaluating the mouth, e.g. the jaw
- A61B5/4552—Evaluating soft tissue within the mouth, e.g. gums or tongue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4806—Sleep evaluation
- A61B5/4818—Sleep apnoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7246—Details of waveform analysis using correlation, e.g. template matching or determination of similarity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
- A61M2021/0005—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
- A61M2021/0072—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus with application of electrical currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0507—Electrodes for the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36057—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for stimulating afferent nerves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37252—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data
- A61N1/37282—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data characterised by communication with experts in remote locations using a network
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/378—Electrical supply
- A61N1/3787—Electrical supply from an external energy source
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/10—Image acquisition modality
- G06T2207/10028—Range image; Depth image; 3D point clouds
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/10—Image acquisition modality
- G06T2207/10032—Satellite or aerial image; Remote sensing
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/10—Image acquisition modality
- G06T2207/10048—Infrared image
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/20—Special algorithmic details
- G06T2207/20212—Image combination
- G06T2207/20224—Image subtraction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/30—Assessment of water resources
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medical Informatics (AREA)
- General Physics & Mathematics (AREA)
- Theoretical Computer Science (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Multimedia (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Artificial Intelligence (AREA)
- Physiology (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Pulmonology (AREA)
- Acoustics & Sound (AREA)
- Software Systems (AREA)
- Psychiatry (AREA)
- Fuzzy Systems (AREA)
- Evolutionary Computation (AREA)
- Mathematical Physics (AREA)
- Signal Processing (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Electromagnetism (AREA)
- Astronomy & Astrophysics (AREA)
Abstract
Description
特性 | 示例1 | 示例2 | 示例3 | 示例4 |
外径(OD) | 30mm | 30mm | 30mm | 26mm |
匝数(N) | 12 | 10 | 8 | 10 |
线圈间距(P) | 1.0mm | 1.0mm | 1.0mm | 1.0mm |
迹线宽度(W) | 0.5mm | 0.5mm | 0.5mm | 0.5mm |
迹线厚度(T) | 1.4密耳 | 1.4密耳 | 1.4密耳 | 1.4密耳 |
线圈间隔(S) | 2密耳 | 2密耳 | 2密耳 | 2密耳 |
最大功率递送 | 32.0mW | 39.4mW | 43.7mW | 23.3mW |
Claims (19)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202310993707.6A CN117122791A (zh) | 2019-05-02 | 2020-05-04 | 用于改善睡眠障碍性呼吸的系统和方法 |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962841978P | 2019-05-02 | 2019-05-02 | |
US62/841,978 | 2019-05-02 | ||
PCT/US2020/031389 WO2020223740A1 (en) | 2019-05-02 | 2020-05-04 | Systems and methods for improving sleep disordered breathing |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202310993707.6A Division CN117122791A (zh) | 2019-05-02 | 2020-05-04 | 用于改善睡眠障碍性呼吸的系统和方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN114051421A true CN114051421A (zh) | 2022-02-15 |
CN114051421B CN114051421B (zh) | 2023-09-05 |
Family
ID=70861545
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202310993707.6A Pending CN117122791A (zh) | 2019-05-02 | 2020-05-04 | 用于改善睡眠障碍性呼吸的系统和方法 |
CN202080048485.5A Pending CN114072193A (zh) | 2019-05-02 | 2020-05-04 | 使用闭环反馈改善睡眠障碍性呼吸的系统和方法 |
CN202080048590.9A Active CN114051421B (zh) | 2019-05-02 | 2020-05-04 | 用于改善睡眠障碍性呼吸的系统和方法 |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202310993707.6A Pending CN117122791A (zh) | 2019-05-02 | 2020-05-04 | 用于改善睡眠障碍性呼吸的系统和方法 |
CN202080048485.5A Pending CN114072193A (zh) | 2019-05-02 | 2020-05-04 | 使用闭环反馈改善睡眠障碍性呼吸的系统和方法 |
Country Status (8)
Country | Link |
---|---|
US (7) | US11291842B2 (zh) |
EP (5) | EP3962593B1 (zh) |
JP (2) | JP2022531007A (zh) |
CN (3) | CN117122791A (zh) |
AU (2) | AU2020266685A1 (zh) |
CA (2) | CA3138871A1 (zh) |
ES (2) | ES2956271T3 (zh) |
WO (3) | WO2020223723A1 (zh) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3637432B1 (en) * | 2018-09-21 | 2022-03-23 | Tata Consultancy Services Limited | System and method for non-apnea sleep arousal detection |
GB2573028B (en) | 2018-10-17 | 2020-04-29 | Signifier Medical Tech Limited | Oral muscle training |
US11654283B2 (en) | 2019-03-06 | 2023-05-23 | Medtronic Xomed, Inc. | Obstructive sleep apnea patient programmer for implantable devices |
ES2956271T3 (es) | 2019-05-02 | 2023-12-18 | Xii Medical Inc | Receptor de potencia de estimulación implantable y sistemas |
EP4045134A1 (en) | 2019-10-15 | 2022-08-24 | XII Medical, Inc. | Biased neuromodulation lead and method of using same |
US11491324B2 (en) | 2019-10-16 | 2022-11-08 | Invicta Medical, Inc. | Adjustable devices for treating sleep apnea, and associated systems and methods |
US11819233B2 (en) | 2020-01-24 | 2023-11-21 | Medtronic Xomed, Inc. | Devices and techniques for separating tissue |
US11666755B2 (en) | 2020-01-24 | 2023-06-06 | Medtronic Xomed, Inc. | System and method for therapy |
US11623086B2 (en) | 2020-01-24 | 2023-04-11 | Medtronic Xomed, Inc. | System and method for therapy |
US11273305B2 (en) | 2020-01-24 | 2022-03-15 | Medtronic Xomed, Inc. | Medical lead for treating obstructive sleep apnea (OSA) with electrical stimulation |
US11426201B2 (en) | 2020-01-24 | 2022-08-30 | Medtronic Xomed, Inc. | Treatment of obstructive sleep apnea (OSA) |
US11464977B2 (en) | 2020-03-23 | 2022-10-11 | Medtronic, Inc. | Obstructive and central sleep apnea combination therapy control |
US11666270B2 (en) | 2020-04-30 | 2023-06-06 | Medtronic Xomed, Inc. | Personalized and contextualized treatment of sleep apnea and obesity comorbidity |
US20220059208A1 (en) * | 2020-08-21 | 2022-02-24 | Stimscience Inc. | Systems, methods, and devices for sleep intervention quality estimation |
US11862312B2 (en) | 2020-08-21 | 2024-01-02 | Stimscience Inc. | Systems, methods, and devices for sleep intervention quality assessment |
EP4240241A4 (en) | 2020-11-04 | 2024-05-29 | Invicta Medical, Inc. | REMOTE POWER DELIVERY IMPLANTABLE ELECTRODES FOR THE TREATMENT OF SLEEP APNEA AND RELATED SYSTEMS AND METHODS |
GB202018997D0 (en) * | 2020-12-02 | 2021-01-13 | Signifier Medical Tech Limited | Oral muscle composition detection and training |
US11666271B2 (en) | 2020-12-09 | 2023-06-06 | Medtronic, Inc. | Detection and monitoring of sleep apnea conditions |
US11691010B2 (en) * | 2021-01-13 | 2023-07-04 | Xii Medical, Inc. | Systems and methods for improving sleep disordered breathing |
US20240100343A1 (en) * | 2021-08-24 | 2024-03-28 | Avivomed, Inc. | Cranial nerve stimulator with therapeutic feedback |
US11925804B2 (en) | 2021-11-03 | 2024-03-12 | Medtronic Xomed, LLC | Multi-device obstructive sleep apnea (OSA) treatment |
CN114391808A (zh) * | 2021-12-23 | 2022-04-26 | 山东师范大学 | 一种基于非线性相互依赖度的睡眠分期方法及系统 |
US20240165411A1 (en) | 2022-11-23 | 2024-05-23 | Xii Medical, Inc. | Methods for analyzing respiration and sleep state |
US11964154B1 (en) | 2022-12-22 | 2024-04-23 | Invicta Medical, Inc. | Signal delivery devices to treat sleep apnea, and associated methods and systems |
CN118001005A (zh) * | 2024-03-26 | 2024-05-10 | 复远数科医疗(杭州)有限公司 | 一种穿戴式无创智能化舌下神经调控系统 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5335657A (en) * | 1991-05-03 | 1994-08-09 | Cyberonics, Inc. | Therapeutic treatment of sleep disorder by nerve stimulation |
US5522862A (en) * | 1994-09-21 | 1996-06-04 | Medtronic, Inc. | Method and apparatus for treating obstructive sleep apnea |
US6314324B1 (en) * | 1999-05-05 | 2001-11-06 | Respironics, Inc. | Vestibular stimulation system and method |
US20100280568A1 (en) * | 2009-04-30 | 2010-11-04 | Cherik Bulkes | Implantable High Efficiency Energy Transfer Module With Near-Field Inductive Coupling |
US20110137376A1 (en) * | 2008-05-26 | 2011-06-09 | Werner Meskens | Multi-coil wireless communication system for an implantable device |
WO2017112960A1 (en) * | 2015-12-23 | 2017-06-29 | Invicta Medical, Inc. | Method and apparatus for predicting disordered breathing |
Family Cites Families (111)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US910774A (en) | 1908-05-09 | 1909-01-26 | Ezra D Beers | Replanting attachment for cultivators. |
US4990160A (en) | 1988-02-16 | 1991-02-05 | Edward Terino | Extended chin and mandible implants |
US5591216A (en) | 1995-05-19 | 1997-01-07 | Medtronic, Inc. | Method for treatment of sleep apnea by electrical stimulation |
US5609621A (en) | 1995-08-04 | 1997-03-11 | Medtronic, Inc. | Right ventricular outflow tract defibrillation lead |
US6198970B1 (en) | 1995-10-27 | 2001-03-06 | Esd Limited Liability Company | Method and apparatus for treating oropharyngeal respiratory and oral motor neuromuscular disorders with electrical stimulation |
FR2745946B1 (fr) | 1996-03-08 | 1998-04-17 | Schneider Electric Sa | Interrupteur ou disjoncteur electrique sous vide |
US5716377A (en) | 1996-04-25 | 1998-02-10 | Medtronic, Inc. | Method of treating movement disorders by brain stimulation |
US5988171A (en) | 1997-06-26 | 1999-11-23 | Influence Medical Technologies, Ltd. | Methods and devices for the treatment of airway obstruction, sleep apnea and snoring |
AU1093099A (en) | 1997-10-17 | 1999-05-10 | Penn State Research Foundation; The | Muscle stimulating device and method for diagnosing and treating a breathin g disorder |
WO2000006249A2 (en) | 1998-07-27 | 2000-02-10 | Case Western Reserve University | Method and apparatus for closed-loop stimulation of the hypoglossal nerve in human patients to treat obstructive sleep apnea |
US6240316B1 (en) | 1998-08-14 | 2001-05-29 | Advanced Bionics Corporation | Implantable microstimulation system for treatment of sleep apnea |
US6212435B1 (en) | 1998-11-13 | 2001-04-03 | Respironics, Inc. | Intraoral electromuscular stimulation device and method |
US20040122787A1 (en) * | 2002-12-18 | 2004-06-24 | Avinash Gopal B. | Enhanced computer-assisted medical data processing system and method |
DE602004014281D1 (de) * | 2003-08-18 | 2008-07-17 | Cardiac Pacemakers Inc | Steuerungsgerät für unregelmässige atmung |
US7668591B2 (en) | 2003-09-18 | 2010-02-23 | Cardiac Pacemakers, Inc. | Automatic activation of medical processes |
US8467876B2 (en) | 2003-10-15 | 2013-06-18 | Rmx, Llc | Breathing disorder detection and therapy delivery device and method |
US7970475B2 (en) | 2003-10-15 | 2011-06-28 | Rmx, Llc | Device and method for biasing lung volume |
US10589087B2 (en) | 2003-11-26 | 2020-03-17 | Wicab, Inc. | Systems and methods for altering brain and body functions and for treating conditions and diseases of the same |
US20070239230A1 (en) | 2004-12-17 | 2007-10-11 | Medtronic, Inc. | System and method for regulating cardiac triggered therapy to the brain |
US7680538B2 (en) | 2005-03-31 | 2010-03-16 | Case Western Reserve University | Method of treating obstructive sleep apnea using electrical nerve stimulation |
US20070160273A1 (en) | 2006-01-10 | 2007-07-12 | Adi Maschiah | Device, system and method for modifying two dimensional data of a body part |
US20070160274A1 (en) | 2006-01-10 | 2007-07-12 | Adi Mashiach | System and method for segmenting structures in a series of images |
US20070263915A1 (en) | 2006-01-10 | 2007-11-15 | Adi Mashiach | System and method for segmenting structures in a series of images |
US20080260229A1 (en) | 2006-05-25 | 2008-10-23 | Adi Mashiach | System and method for segmenting structures in a series of images using non-iodine based contrast material |
US7660632B2 (en) | 2006-06-30 | 2010-02-09 | Ric Investments, Llc | Method and apparatus for hypoglossal nerve stimulation |
US20080039904A1 (en) | 2006-08-08 | 2008-02-14 | Cherik Bulkes | Intravascular implant system |
US9186511B2 (en) | 2006-10-13 | 2015-11-17 | Cyberonics, Inc. | Obstructive sleep apnea treatment devices, systems and methods |
US9913982B2 (en) | 2011-01-28 | 2018-03-13 | Cyberonics, Inc. | Obstructive sleep apnea treatment devices, systems and methods |
US8417343B2 (en) | 2006-10-13 | 2013-04-09 | Apnex Medical, Inc. | Obstructive sleep apnea treatment devices, systems and methods |
US9744354B2 (en) | 2008-12-31 | 2017-08-29 | Cyberonics, Inc. | Obstructive sleep apnea treatment devices, systems and methods |
US9095709B2 (en) | 2006-12-22 | 2015-08-04 | Second Sight Medical Products, Inc. | Visual prosthetic apparatus for retinal stimulation |
US7937246B2 (en) | 2007-09-07 | 2011-05-03 | Board Of Regents Of The University Of Nebraska | Vertical track modulus trending |
US20080260217A1 (en) | 2007-04-23 | 2008-10-23 | Adi Mashiach | System and method for designating a boundary of a vessel in an image |
WO2009007896A2 (en) | 2007-07-06 | 2009-01-15 | Innovea Medical Ltd. | System and method for designating volumetric dimensions of vascular matter |
US7885713B2 (en) | 2007-07-11 | 2011-02-08 | Ampcare, Llc | Method and apparatus for laryngeal elevator musculature rehabilitation |
US10076655B2 (en) | 2007-09-21 | 2018-09-18 | Koninklijke Philips N.V. | Vestibular stimulation system |
US20100198103A1 (en) | 2007-10-09 | 2010-08-05 | Imthera Medical, Inc. | System and method for neural stimulation |
US7760776B2 (en) | 2007-11-02 | 2010-07-20 | Glen Ivan Redford | Scalable, reconfigurable, laser combiner |
US20090226057A1 (en) | 2008-03-04 | 2009-09-10 | Adi Mashiach | Segmentation device and method |
US8204602B2 (en) * | 2008-04-23 | 2012-06-19 | Medtronic, Inc. | Recharge system and method for deep or angled devices |
JP5309210B2 (ja) | 2008-04-29 | 2013-10-09 | カーディアック ペースメイカーズ, インコーポレイテッド | 脊髄刺激を送達する刺激送達システム |
EP2296751A1 (en) | 2008-06-03 | 2011-03-23 | Medtronic, Inc. | Bifurcated lead system and apparatus |
WO2010006218A2 (en) | 2008-07-11 | 2010-01-14 | Don Headley | Sleep apnea device and method |
US8428725B2 (en) | 2008-10-09 | 2013-04-23 | Imthera Medical, Inc. | Method of stimulating a Hypoglossal nerve for controlling the position of a patient's tongue |
EP4258513A3 (en) | 2008-10-10 | 2023-10-25 | Implantica Patent Ltd. | Charger for implant |
EP2389224B1 (en) * | 2008-11-19 | 2017-03-01 | Inspire Medical Systems, Inc. | Device treating sleep disordered breathing |
US20100179562A1 (en) | 2009-01-14 | 2010-07-15 | Linker Fred I | Stimulation leads, delivery systems and methods of use |
US9486628B2 (en) | 2009-03-31 | 2016-11-08 | Inspire Medical Systems, Inc. | Percutaneous access for systems and methods of treating sleep apnea |
CN102497823B (zh) | 2009-05-15 | 2016-05-11 | 脊髓调制公司 | 用于神经调节脊柱解剖结构的方法、系统和装置 |
WO2011016864A1 (en) | 2009-08-05 | 2011-02-10 | Ndi Medical, Llc | Systems and methods for maintaining airway patency |
US9409013B2 (en) | 2009-10-20 | 2016-08-09 | Nyxoah SA | Method for controlling energy delivery as a function of degree of coupling |
US9415215B2 (en) | 2009-10-20 | 2016-08-16 | Nyxoah SA | Methods for treatment of sleep apnea |
US10806926B2 (en) | 2009-10-20 | 2020-10-20 | Man & Science Sa | Implantable electrical stimulator |
US8585617B2 (en) | 2009-12-21 | 2013-11-19 | Nyxoah SA | Diagnosis and prediction of obstructive sleep apnea |
US10716940B2 (en) | 2009-10-20 | 2020-07-21 | Nyxoah SA | Implant unit for modulation of small diameter nerves |
US10751537B2 (en) | 2009-10-20 | 2020-08-25 | Nyxoah SA | Arced implant unit for modulation of nerves |
AU2010318651A1 (en) | 2009-11-10 | 2012-05-03 | Imthera Medical, Inc. | System for stimulating a hypoglossal nerve for controlling the position of a patient's tongue |
US8983610B2 (en) | 2009-11-18 | 2015-03-17 | Case Western Reserve University | Hybrid method for modulating upper airway function in a subject |
WO2011112843A1 (en) | 2010-03-12 | 2011-09-15 | Inspire Medical Systems, Inc. | Method and system for identifying a location for nerve stimulation |
US20110230702A1 (en) | 2010-03-16 | 2011-09-22 | Kirk Honour | Device, System, And Method For Treating Sleep Apnea |
WO2012052882A1 (en) | 2010-10-20 | 2012-04-26 | Koninklijke Philips Electronics N.V. | Method and apparatus for diagnosing obstructive sleep apnea with an awake patient |
WO2012071402A1 (en) | 2010-11-23 | 2012-05-31 | Cardiac Pacemakers, Inc. | Modular antenna for implantable medical device |
CA2850436C (en) | 2011-09-30 | 2021-06-22 | Adi Mashiach | Apparatus and method for controlling energy delivery as a function of degree of coupling |
WO2013057597A1 (pt) | 2011-10-17 | 2013-04-25 | Cordenet-Produtora De Redes Agricolas, S.A. | Rede tricotada para o envolvimento de produtos agricolas |
JP2013208182A (ja) | 2012-03-30 | 2013-10-10 | Olympus Corp | 除細動電極 |
EP2844141A1 (en) | 2012-05-01 | 2015-03-11 | Advanced Bionics AG | Electromyography response detection systems and methods |
AU2013263068B2 (en) | 2012-05-15 | 2016-09-29 | Imthera Medical, Inc. | Stimulation of a hypoglossal nerve for controlling the position of a patient's tongue |
WO2013177621A1 (en) | 2012-05-30 | 2013-12-05 | Resmed Sensor Technologies Limited | Method and apparatus for monitoring cardio-pulmonary health |
US9504828B2 (en) | 2012-07-26 | 2016-11-29 | Nyxoah SA | Electrical contacts on a medical device patch |
US10052097B2 (en) | 2012-07-26 | 2018-08-21 | Nyxoah SA | Implant unit delivery tool |
US11253712B2 (en) | 2012-07-26 | 2022-02-22 | Nyxoah SA | Sleep disordered breathing treatment apparatus |
US9907967B2 (en) | 2012-07-26 | 2018-03-06 | Adi Mashiach | Transcutaneous power conveyance device |
US9511238B2 (en) | 2012-07-26 | 2016-12-06 | Nyxoah SA | Implant holder and suture guide |
NZ725344A (en) | 2012-09-19 | 2018-04-27 | Resmed Sensor Tech Ltd | System and method for determining sleep stage |
DE202012009867U1 (de) | 2012-10-16 | 2012-11-26 | em-tec GmbH Werner Heinze | Spule zur induktiven transkutanen Übertragung hoher Leistungen |
US20140135868A1 (en) | 2012-11-09 | 2014-05-15 | Jacob Bashyam Bashyam | Non-invasive intraoral electrical stimulator system and method for treatment of obstructive sleep apnea (osa) |
WO2014096973A2 (en) | 2012-12-19 | 2014-06-26 | Adi Mashiach | Systems and methods for internal analyte sensing |
US10238875B2 (en) | 2012-12-19 | 2019-03-26 | Adi Mashiach | Systems and methods for hypertension control |
US20150314126A1 (en) | 2012-12-19 | 2015-11-05 | Cephalix SA | Systems and Methods for the Treatment of Head Pain |
US9837704B2 (en) | 2013-03-14 | 2017-12-05 | Neuropace, Inc. | Anatomically compliant antenna for implantable medical device |
WO2014165834A1 (en) | 2013-04-05 | 2014-10-09 | Waseem Ahmad | Devices and methods for airflow diagnosis and restoration |
JP6306288B2 (ja) * | 2013-05-13 | 2018-04-04 | 日東電工株式会社 | コイルプリント配線基板、受電モジュール、電池ユニットおよび受電通信モジュール |
US9643022B2 (en) | 2013-06-17 | 2017-05-09 | Nyxoah SA | Flexible control housing for disposable patch |
US9917356B2 (en) * | 2013-09-13 | 2018-03-13 | Lawrence Livermore National Security, Llc | Band-notched spiral antenna |
US9387332B2 (en) | 2013-10-08 | 2016-07-12 | Medtronic, Inc. | Implantable medical devices having hollow sleeve cofire ceramic structures and methods of fabricating the same |
WO2015077283A1 (en) * | 2013-11-19 | 2015-05-28 | The Cleveland Clinic Foundation | System for treating obstructive sleep apnea |
US20170143257A1 (en) * | 2014-01-07 | 2017-05-25 | Invicta Medical, Inc. | Determining a level of compliance using a device for treatment of disordered breathing |
US20170143280A1 (en) | 2014-01-07 | 2017-05-25 | Invicta Medical, Inc. | Determining a type of disordered breathing |
US20160106976A1 (en) | 2014-01-10 | 2016-04-21 | Theodore R. Kucklick | Device and method for treatment of sleep apnea |
US11383083B2 (en) | 2014-02-11 | 2022-07-12 | Livanova Usa, Inc. | Systems and methods of detecting and treating obstructive sleep apnea |
WO2015139053A1 (en) | 2014-03-14 | 2015-09-17 | Accelemed, Llc | Method and apparatus for versatile minimally invasive neuromodulators |
US20150265221A1 (en) | 2014-03-19 | 2015-09-24 | Boston Scientific Scimed, Inc. | Methods and systems for diagnostic monitoring |
JPWO2016027359A1 (ja) | 2014-08-22 | 2017-06-29 | 富士通株式会社 | 状態推定方法、状態推定システム、衣服及び監視システム |
AU2016215030B2 (en) | 2015-02-06 | 2020-06-18 | Nalu Medical, Inc. | Medical apparatus including an implantable system and an external system |
CN106329096B (zh) | 2015-06-30 | 2020-03-31 | 比亚迪股份有限公司 | Nfc天线 |
US10195428B2 (en) | 2015-09-29 | 2019-02-05 | Medtronic, Inc. | Neural stimulation to treat sleep apnea |
EP3377168B1 (en) * | 2015-11-17 | 2023-06-21 | Inspire Medical Systems, Inc. | Microstimulation sleep disordered breathing (sdb) therapy device |
EP3439545A4 (en) | 2016-04-01 | 2019-11-27 | Medical Inc. Kobara | MODULATED EPICARDIC DERIVATION AND PLACEMENT SYSTEM AND METHOD |
US10470921B2 (en) | 2016-04-07 | 2019-11-12 | Achaemenid, Llc | Removable mandibular myo-stimulator |
AU2017252643B2 (en) | 2016-04-19 | 2022-04-14 | Inspire Medical Systems, Inc. | Accelerometer-based sensing for sleep disordered breathing (SDB) care |
JP2019524389A (ja) * | 2016-06-10 | 2019-09-05 | ジャック ウィリアムズ | 生体電気事象を無線で記録及び刺激するためのシステム |
WO2018017508A1 (en) | 2016-07-18 | 2018-01-25 | Peerbridge Health, Inc. | System and method for treating sleep apnea |
US10179052B2 (en) | 2016-07-28 | 2019-01-15 | Depuy Ireland Unlimited Company | Total knee implant prosthesis assembly and method |
US20180117312A1 (en) | 2016-10-31 | 2018-05-03 | The Alfred E. Mann Foundation For Scientific Research | Nerve cuff electrodes fabricated using over-molded lcp substrates |
US11123567B2 (en) | 2017-02-07 | 2021-09-21 | Advanced Bionics Ag | Antenna apparatus for use with medical implants |
US10765862B2 (en) * | 2017-10-24 | 2020-09-08 | Vanderbilt University | Systems and methods for treating sleep disordered breathing |
US11771899B2 (en) | 2018-07-10 | 2023-10-03 | The Cleveland Clinic Foundation | System and method for treating obstructive sleep apnea |
ES2956271T3 (es) | 2019-05-02 | 2023-12-18 | Xii Medical Inc | Receptor de potencia de estimulación implantable y sistemas |
US11351377B2 (en) | 2019-05-03 | 2022-06-07 | The Cleveland Clinic Foundation | Intra-oral appliances and systems |
EP4045134A1 (en) | 2019-10-15 | 2022-08-24 | XII Medical, Inc. | Biased neuromodulation lead and method of using same |
US11691010B2 (en) | 2021-01-13 | 2023-07-04 | Xii Medical, Inc. | Systems and methods for improving sleep disordered breathing |
-
2020
- 2020-05-04 ES ES20729309T patent/ES2956271T3/es active Active
- 2020-05-04 WO PCT/US2020/031266 patent/WO2020223723A1/en unknown
- 2020-05-04 US US16/866,523 patent/US11291842B2/en active Active
- 2020-05-04 WO PCT/US2020/031383 patent/WO2020223738A1/en unknown
- 2020-05-04 EP EP20729318.4A patent/EP3962593B1/en active Active
- 2020-05-04 EP EP20729309.3A patent/EP3962592B1/en active Active
- 2020-05-04 WO PCT/US2020/031389 patent/WO2020223740A1/en unknown
- 2020-05-04 ES ES20729318T patent/ES2955341T3/es active Active
- 2020-05-04 CN CN202310993707.6A patent/CN117122791A/zh active Pending
- 2020-05-04 AU AU2020266685A patent/AU2020266685A1/en active Pending
- 2020-05-04 CN CN202080048485.5A patent/CN114072193A/zh active Pending
- 2020-05-04 CN CN202080048590.9A patent/CN114051421B/zh active Active
- 2020-05-04 EP EP20728849.9A patent/EP3962585B1/en active Active
- 2020-05-04 US US16/866,488 patent/US11420063B2/en active Active
- 2020-05-04 EP EP23187373.8A patent/EP4241690A3/en active Pending
- 2020-05-04 AU AU2020264530A patent/AU2020264530A1/en active Pending
- 2020-05-04 EP EP23189996.4A patent/EP4272644A3/en active Pending
- 2020-05-04 CA CA3138871A patent/CA3138871A1/en active Pending
- 2020-05-04 JP JP2021565717A patent/JP2022531007A/ja active Pending
- 2020-05-04 CA CA3138870A patent/CA3138870A1/en active Pending
- 2020-05-04 US US16/865,541 patent/US11351380B2/en active Active
- 2020-05-04 JP JP2021565077A patent/JP2022531411A/ja active Pending
-
2022
- 2022-03-11 US US17/654,451 patent/US20220266030A1/en active Pending
- 2022-05-02 US US17/661,705 patent/US20230024498A1/en not_active Abandoned
- 2022-08-03 US US17/817,192 patent/US11869211B2/en active Active
-
2023
- 2023-12-21 US US18/392,491 patent/US20240198108A1/en active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5335657A (en) * | 1991-05-03 | 1994-08-09 | Cyberonics, Inc. | Therapeutic treatment of sleep disorder by nerve stimulation |
US5522862A (en) * | 1994-09-21 | 1996-06-04 | Medtronic, Inc. | Method and apparatus for treating obstructive sleep apnea |
US6314324B1 (en) * | 1999-05-05 | 2001-11-06 | Respironics, Inc. | Vestibular stimulation system and method |
US20110137376A1 (en) * | 2008-05-26 | 2011-06-09 | Werner Meskens | Multi-coil wireless communication system for an implantable device |
US20100280568A1 (en) * | 2009-04-30 | 2010-11-04 | Cherik Bulkes | Implantable High Efficiency Energy Transfer Module With Near-Field Inductive Coupling |
WO2017112960A1 (en) * | 2015-12-23 | 2017-06-29 | Invicta Medical, Inc. | Method and apparatus for predicting disordered breathing |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN114051421B (zh) | 用于改善睡眠障碍性呼吸的系统和方法 | |
US20230001192A1 (en) | Systems And Methods Of Detecting And Treating Obstructive Sleep Apnea | |
US11691010B2 (en) | Systems and methods for improving sleep disordered breathing | |
US11471685B2 (en) | Obstructive sleep apnea treatment devices, systems and methods | |
USRE48024E1 (en) | Obstructive sleep apnea treatment devices, systems and methods | |
US9333351B2 (en) | Neurostimulation method and system to treat apnea | |
US20050085865A1 (en) | Breathing disorder detection and therapy delivery device and method | |
EP3061493A1 (en) | Obstructive sleep apnea treatment devices | |
WO2015051140A1 (en) | Obstructive sleep apnea treatment screening methods | |
US20240108899A1 (en) | Neuromodulation devices and associated systems and methods | |
EP3052011A1 (en) | Obstructive sleep apnea treatment screening methods |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: A. V. cappasso Inventor after: Nichols Jennifer Inventor after: F. A. Pape Inventor after: K. Emerson Inventor before: A. V. cappasso Inventor before: Nichols Jennifer |
|
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20230810 Address after: Ohio, USA Applicant after: Twelve Pharmaceutical Co.,Ltd. Applicant after: THE CLEVELAND CLINIC FOUNDATION Address before: Ohio, USA Applicant before: Twelve Pharmaceutical Co.,Ltd. |
|
GR01 | Patent grant | ||
GR01 | Patent grant |