CN114007620B - 二氨基嘧啶类化合物治疗子宫内膜异位相关的疼痛的方法 - Google Patents

二氨基嘧啶类化合物治疗子宫内膜异位相关的疼痛的方法 Download PDF

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Publication number
CN114007620B
CN114007620B CN202080032509.8A CN202080032509A CN114007620B CN 114007620 B CN114007620 B CN 114007620B CN 202080032509 A CN202080032509 A CN 202080032509A CN 114007620 B CN114007620 B CN 114007620B
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days
compound
pain
administration
medicament
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CN114007620A (zh
Inventor
赵焰平
黄淮
王红军
姜媛媛
梁会宁
安然
兰洲
王瑾
周丽莹
刘亚男
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Beijing Tide Pharmaceutical Co Ltd
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Beijing Tide Pharmaceutical Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202080032509.8A 2019-04-30 2020-04-29 二氨基嘧啶类化合物治疗子宫内膜异位相关的疼痛的方法 Active CN114007620B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2019/085209 2019-04-30
CN2019085209 2019-04-30
PCT/CN2020/087689 WO2020221277A1 (zh) 2019-04-30 2020-04-29 二氨基嘧啶类化合物治疗子宫内膜异位相关的疼痛的方法

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CN114007620A CN114007620A (zh) 2022-02-01
CN114007620B true CN114007620B (zh) 2024-08-06

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Country Link
US (1) US12605381B2 (https=)
EP (1) EP3960178B1 (https=)
JP (1) JP7663508B2 (https=)
KR (1) KR102935431B1 (https=)
CN (1) CN114007620B (https=)
AU (1) AU2020266947B2 (https=)
BR (1) BR112021021838A8 (https=)
CA (1) CA3138238A1 (https=)
MX (1) MX2021013347A (https=)
SG (1) SG11202111960PA (https=)
TW (1) TWI737285B (https=)
WO (1) WO2020221277A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7207634B2 (ja) 2017-11-01 2023-01-18 ベイジン タイド ファーマシューティカル カンパニー リミテッド Ｐ２ｘ３及び／又はｐ２ｘ２／３受容体アンタゴニスト、それを含む医薬組成物及びその使用
US20250032476A1 (en) * 2021-11-05 2025-01-30 The Regents Of The University Of California Alpha-2a adrenergic receptor modulators and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108779119A (zh) * 2016-03-25 2018-11-09 传入制药公司 嘧啶及其变体、及其用途
CN108834412A (zh) * 2016-03-14 2018-11-16 传入制药公司 嘧啶及其变体、及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008104474A1 (en) * 2007-02-28 2008-09-04 F. Hoffmann-La Roche Ag Diaminopyrimidines
JP7207634B2 (ja) * 2017-11-01 2023-01-18 ベイジン タイド ファーマシューティカル カンパニー リミテッド Ｐ２ｘ３及び／又はｐ２ｘ２／３受容体アンタゴニスト、それを含む医薬組成物及びその使用
USD956213S1 (en) 2020-10-02 2022-06-28 Phillips-Medisize A/S Autoinjector

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108834412A (zh) * 2016-03-14 2018-11-16 传入制药公司 嘧啶及其变体、及其用途
CN108779119A (zh) * 2016-03-25 2018-11-09 传入制药公司 嘧啶及其变体、及其用途

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
P2X3 receptor involvement in endometriosis pain via ERK signaling pathway;Shaojie Ding等;PLOS ONE;第12卷(第9期);1-17 *

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Publication number Publication date
BR112021021838A8 (pt) 2023-02-28
JP7663508B2 (ja) 2025-04-16
BR112021021838A2 (pt) 2022-01-04
KR20220008286A (ko) 2022-01-20
SG11202111960PA (en) 2021-12-30
CA3138238A1 (en) 2020-11-05
EP3960178A1 (en) 2022-03-02
JP2022531570A (ja) 2022-07-07
US20220249478A1 (en) 2022-08-11
MX2021013347A (es) 2022-01-24
TW202106303A (zh) 2021-02-16
KR102935431B1 (ko) 2026-03-05
CN114007620A (zh) 2022-02-01
WO2020221277A1 (zh) 2020-11-05
EP3960178B1 (en) 2026-03-18
US12605381B2 (en) 2026-04-21
TWI737285B (zh) 2021-08-21
AU2020266947A1 (en) 2021-12-16
EP3960178A4 (en) 2023-01-25
AU2020266947B2 (en) 2025-10-09

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