CN113908064A - 一种凝胶基质及其制备方法 - Google Patents
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Abstract
本发明公开了一种凝胶基质,按质量份数计,该凝胶基质的配方包括:聚乙烯醇、壳聚糖、芦荟凝胶、明胶凝胶、甘油、聚乙二醇、保湿剂、交联剂、PH调节剂、去离子水、植物提取香精、抑菌剂、卡波姆、纤维素衍生物以及海藻酸份;本发明还提供一种凝胶基质及其制备方法,包括常温搅拌、低温搅拌、分装入模、反复冻融固化;通过在配方中添加了芦荟凝胶、明胶凝胶以及聚乙二醇等成分,凝胶在凝结时会与配方成分中的聚乙烯醇、卡波姆等结合,从而提高凝胶基质生产出来的面膜的附着效果;在凝胶、醇类与保湿剂的作用下,凝胶基质可对水份和香精进行吸附,使得凝胶基质生产的面膜获得较好的亲肤,使用者则会获得较好的使用体验。
Description
技术领域
本发明属于凝胶基质制备技术领域,具体涉及一种凝胶基质;尤其还涉及一种凝胶基质的制备方法。
背景技术
凝胶是由亲水性聚合物和填充在聚合物链之间的水组成的一种永久性的三维交联聚合物网络。不同高分子链之间发生交联,网络结构就会表现出粘弹性或者纯粹的弹性。水凝胶因柔软和橡胶性质,使其和人体皮肤的质地和灵活性相似,以具有美容功效及其他高生物相容性、生物可降解性、生理惰性的高分子材料做成水凝胶面膜的成膜基质,可隔离空气中的污染物,保护皮肤免受物理刺激,并且贴服皮肤后能持续给皮肤补水,根据湿性愈合环境理论,可促进皮肤伤口愈合,修复,且不与伤口粘连,不破坏新生上皮和肉芽组织,使用舒适,对急性皮肤损伤(如过敏、长痘、擦伤等)有良好效果。
在以水凝胶为基质的面膜内注入海藻糖、芦荟凝胶、珍珠粉、透明质酸、熊果苷、胶原蛋白、绿茶提取物、木瓜蛋白酶等有效活性美容成分,可制成多种功能的面膜。
然而在实际的配方生产过程中,生产出来的面膜的附着能力往往较差,且常规凝胶基质生产出的面膜的亲肤性较差,则会对使用者的使用体验产生影响,因此我们提出一种凝胶基质及其制备方法,能有效的提高鸡群的免疫力。
发明内容
本发明的目的在于提供一种凝胶基质及其制备方法,以解决上述背景技术中常规凝胶基质生产出来的面膜的附着能力往往较差,且常规凝胶基质生产出的面膜的亲肤性较差,会对使用者的使用体验产生影响的问题。
为实现上述目的,本发明采用了如下技术方案:一种凝胶基质,按质量份数计,该凝胶基质的配方包括:聚乙烯醇10-50份、壳聚糖10-50份、芦荟凝胶50-100份、明胶凝胶50-100份、甘油10-50份、聚乙二醇10-30份、保湿剂10-30份、交联剂10-20份、PH调节剂10-30份、去离子水50-100份、植物提取香精1-5份、抑菌剂1-10份、卡波姆10-50份、纤维素衍生物10-30份以及海藻酸钠1-10份。
优选的,聚乙烯醇10份、壳聚糖10份、芦荟凝胶50份、明胶凝胶50份、甘油10份、聚乙二醇10份、保湿剂10份、交联剂10份、PH调节剂10份、去离子水50份、植物提取香精1份、抑菌剂1份、卡波姆10份、纤维素衍生物10份以及海藻酸钠1份。
优选的,聚乙烯醇50份、壳聚糖50份、芦荟凝胶100份、明胶凝胶100份、甘油50份、聚乙二醇30份、保湿剂30份、交联剂20份、PH调节剂30份、去离子水100份、植物提取香精5份、抑菌剂10份、卡波姆50份、纤维素衍生物30份以及海藻酸钠10份。
优选的,所述聚乙烯醇设置为醇解度为98~99(m01)%的PVA-124聚乙烯醇,所述卡波姆设置为羧酸基含量为60%-68%的干燥品卡波姆,所述纤维素衍生物设置为羧甲基纤维素钠。
本发明还提供一种凝胶基质及其制备方法,包括以下步骤:
S1、常温搅拌,将称量好的基料的各个配方配料逐一放入搅拌反应釜中,对添加到反应釜中的配料进行搅拌,在常规室温下对反应釜中配料进行持续搅拌直至混合均匀;
S2、低温搅拌,对反应釜进行降温并使搅拌桨进行持续搅拌,继续搅拌直至混合均匀,通过配方中的PH调节剂对内部的配方搅拌的PH值进行调节;
S3、分装入模,将步骤S2中的搅拌混合物分装至多个凝胶模具中,使其在常温下呈凝固状态,对盛放凝胶的模具进行封装防止杂菌有害物进入;
S4、反复冻融固化,将凝胶基质连通盛放凝胶基质的模具一同移送至腔体中,将盛放凝胶基质的模具在腔体中摆放整齐,并通过蒸汽加热器对腔体内通过高温整体对凝胶基质进行升温融化,再使其自动降至常温固化,经过融化固化处理3-5次;
S5、脱模封装,将经过多次的融化固化处理后将凝胶基质的温度将至常温,使凝胶基质在模具中凝固并将凝胶基质从凝胶基质中取出,并将凝胶基质移送至储存设备中并进行密封封装。
优选的,步骤S1与S2中,反应釜设置为带有搅拌功能的控温反应釜,反应釜的搅拌转速低于5r/min,步骤S1中反应釜的搅拌温度为40-60℃,步骤S1中反应釜的搅拌温度为0-10℃。
优选的,步骤S4中,蒸汽加热器的蒸汽输出温度为30-80℃,蒸汽加热器的蒸汽输出持续时间为20-30min。
优选的,步骤S5中,脱模的过程和密封封装过程均需要在无菌环境下进行。
与现有技术相比,本发明的技术效果和优点:通过在配方中添加了芦荟凝胶、明胶凝胶以及聚乙二醇等成分,各种凝胶在凝结时会与配方成分中的聚乙烯醇、卡波姆等结合,从而提高凝胶基质生产出来的面膜的附着效果;另外在凝胶、醇类与保湿剂的作用下,凝胶基质可对水份和香精进行吸附,从而使得凝胶基质生产的面膜获得较好的亲肤,使用者则会获得较好的使用体验。
具体实施方式
下面将对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。此处所描述的具体实施例仅仅用以解释本发明,并不用于限定本发明。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。
实施例1
一种凝胶基质,按质量份数计,该凝胶基质的配方包括:聚乙烯醇10份、壳聚糖10份、芦荟凝胶50份、明胶凝胶50份、甘油10份、聚乙二醇10份、保湿剂10份、交联剂10份、PH调节剂10份、去离子水50份、植物提取香精1份、抑菌剂1份、卡波姆10份、纤维素衍生物10份以及海藻酸钠1份。
进一步的,聚乙烯醇设置为醇解度为98~99(m01)%的PVA-124聚乙烯醇,卡波姆设置为羧酸基含量为60%-68%的干燥品卡波姆,纤维素衍生物设置为羧甲基纤维素钠。
本发明还提供一种凝胶基质及其制备方法,包括以下步骤:
S1、常温搅拌,将称量好的基料的各个配方配料逐一放入搅拌反应釜中,对添加到反应釜中的配料进行搅拌,在常规室温下对反应釜中配料进行持续搅拌直至混合均匀;
S2、低温搅拌,对反应釜进行降温并使搅拌桨进行持续搅拌,继续搅拌直至混合均匀,通过配方中的PH调节剂对内部的配方搅拌的PH值进行调节;
S3、分装入模,将步骤S2中的搅拌混合物分装至多个凝胶模具中,使其在常温下呈凝固状态,对盛放凝胶的模具进行封装防止杂菌有害物进入;
S4、反复冻融固化,将凝胶基质连通盛放凝胶基质的模具一同移送至腔体中,将盛放凝胶基质的模具在腔体中摆放整齐,并通过蒸汽加热器对腔体内通过高温整体对凝胶基质进行升温融化,再使其自动降至常温固化,经过融化固化处理3-5次;
S5、脱模封装,将经过多次的融化固化处理后将凝胶基质的温度将至常温,使凝胶基质在模具中凝固并将凝胶基质从凝胶基质中取出,并将凝胶基质移送至储存设备中并进行密封封装。
进一步的,步骤S1与S2中,反应釜设置为带有搅拌功能的控温反应釜,反应釜的搅拌转速低于5r/min,步骤S1中反应釜的搅拌温度为40-60℃,步骤S1中反应釜的搅拌温度为0-10℃。
进一步的,步骤S4中,蒸汽加热器的蒸汽输出温度为30-80℃,蒸汽加热器的蒸汽输出持续时间为20-30min。
进一步的,步骤S5中,脱模的过程和密封封装过程均需要在无菌环境下进行。
实施例2
与实施例1不同的是,按质量份数计,该凝胶基质的配方包括:聚乙烯醇50份、壳聚糖50份、芦荟凝胶100份、明胶凝胶100份、甘油50份、聚乙二醇30份、保湿剂30份、交联剂20份、PH调节剂30份、去离子水100份、植物提取香精5份、抑菌剂10份、卡波姆50份、纤维素衍生物30份以及海藻酸钠10份。
实施例3
与实施例1不同的是,按质量份数计,该凝胶基质的配方包括:聚乙烯醇20份、壳聚糖20份、芦荟凝胶60份、明胶凝胶60份、甘油20份、聚乙二醇15份、保湿剂15份、交联剂13份、PH调节剂15份、去离子水60份、植物提取香精2份、抑菌剂3份、卡波姆20份、纤维素衍生物15份以及海藻酸钠3份。
实施例4
与实施例1不同的是,按质量份数计,该凝胶基质的配方包括:聚乙烯醇30份、壳聚糖30份、芦荟凝胶70份、明胶凝胶70份、甘油30份、聚乙二醇20份、保湿剂20份、交联剂16份、PH调节剂20份、去离子水70份、植物提取香精3份、抑菌剂6份、卡波姆30份、纤维素衍生物20份以及海藻酸钠6份。
实施例5
与实施例1不同的是,按质量份数计,该凝胶基质的配方包括:聚乙烯醇40份、壳聚糖40份、芦荟凝胶80份、明胶凝胶80份、甘油40份、聚乙二醇25份、保湿剂25份、交联剂19份、PH调节剂25份、去离子水80份、植物提取香精4份、抑菌剂9份、卡波姆40份、纤维素衍生物25份以及海藻酸钠9份。
本发明三组实施例的具体配方数据如附图1。图1为三组实施例的具体配方数据表。综上所述,本发明通过在配方中添加了芦荟凝胶、明胶凝胶以及聚乙二醇等成分,各种凝胶在凝结时会与配方成分中的聚乙烯醇、卡波姆等结合,从而提高凝胶基质生产出来的面膜的附着效果;另外在凝胶、醇类与保湿剂的作用下,凝胶基质可对水份和香精进行吸附,从而使得凝胶基质生产的面膜获得较好的亲肤,使用者则会获得较好的使用体验。
最后应说明的是:以上所述仅为本发明的优选实施例而已,并不用于限制本发明,尽管参照前述实施例对本发明进行了详细的说明,对于本领域的技术人员来说,其依然可以对前述各实施例所记载的技术方案进行修改,或者对其中部分技术特征进行等同替换,凡在本发明的精神和原则之内,所作的任何修改、等同替换、改进等,均应包含在本发明的保护范围之内。
Claims (8)
1.一种凝胶基质,其特征在于:按质量份数计,该凝胶基质的配方包括:聚乙烯醇10-50份、壳聚糖10-50份、芦荟凝胶50-100份、明胶凝胶50-100份、甘油10-50份、聚乙二醇10-30份、保湿剂10-30份、交联剂10-20份、PH调节剂10-30份、去离子水50-100份、植物提取香精1-5份、抑菌剂1-10份、卡波姆10-50份、纤维素衍生物10-30份以及海藻酸钠1-10份。
2.根据权利要求1所述的一种凝胶基质,其特征在于:聚乙烯醇10份、壳聚糖10份、芦荟凝胶50份、明胶凝胶50份、甘油10份、聚乙二醇10份、保湿剂10份、交联剂10份、PH调节剂10份、去离子水50份、植物提取香精1份、抑菌剂1份、卡波姆10份、纤维素衍生物10份以及海藻酸钠1份。
3.根据权利要求1所述的一种凝胶基质,其特征在于:聚乙烯醇50份、壳聚糖50份、芦荟凝胶100份、明胶凝胶100份、甘油50份、聚乙二醇30份、保湿剂30份、交联剂20份、PH调节剂30份、去离子水100份、植物提取香精5份、抑菌剂10份、卡波姆50份、纤维素衍生物30份以及海藻酸钠10份。
4.根据权利要求1所述的一种凝胶基质,其特征在于:所述聚乙烯醇设置为醇解度为98~99(m01)%的PVA-124聚乙烯醇,所述卡波姆设置为羧酸基含量为60%-68%的干燥品卡波姆,所述纤维素衍生物设置为羧甲基纤维素钠。
5.一种权利要求1所述的凝胶基质的制备方法,其特征在于,包括以下步骤:
S1、常温搅拌,将称量好的基料的各个配方配料逐一放入搅拌反应釜中,对添加到反应釜中的配料进行搅拌,在常规室温下对反应釜中配料进行持续搅拌直至混合均匀;
S2、低温搅拌,对反应釜进行降温并使搅拌桨进行持续搅拌,继续搅拌直至混合均匀,通过配方中的PH调节剂对内部的配方搅拌的PH值进行调节;
S3、分装入模,将步骤S2中的搅拌混合物分装至多个凝胶模具中,使其在常温下呈凝固状态,对盛放凝胶的模具进行封装防止杂菌有害物进入;
S4、反复冻融固化,将凝胶基质连通盛放凝胶基质的模具一同移送至腔体中,将盛放凝胶基质的模具在腔体中摆放整齐,并通过蒸汽加热器对腔体内通过高温整体对凝胶基质进行升温融化,再使其自动降至常温固化,经过融化固化处理3-5次;
S5、脱模封装,将经过多次的融化固化处理后将凝胶基质的温度将至常温,使凝胶基质在模具中凝固并将凝胶基质从凝胶基质中取出,并将凝胶基质移送至储存设备中并进行密封封装。
6.根据权利要求5所述的一种凝胶基质的制备方法,其特征在于:步骤S1与S2中,反应釜设置为带有搅拌功能的控温反应釜,反应釜的搅拌转速低于5r/min,步骤S1中反应釜的搅拌温度为40-60℃,步骤S1中反应釜的搅拌温度为0-10℃。
7.根据权利要求5所述的一种凝胶基质的制备方法,其特征在于:步骤S4中,蒸汽加热器的蒸汽输出温度为30-80℃,蒸汽加热器的蒸汽输出持续时间为20-30min。
8.根据权利要求5所述的一种凝胶基质的制备方法,其特征在于:步骤S5中,脱模的过程和密封封装过程均需要在无菌环境下进行。
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