CN113905769A - 超多孔水凝胶、其制造方法和包含其的制品 - Google Patents
超多孔水凝胶、其制造方法和包含其的制品 Download PDFInfo
- Publication number
- CN113905769A CN113905769A CN202080040612.7A CN202080040612A CN113905769A CN 113905769 A CN113905769 A CN 113905769A CN 202080040612 A CN202080040612 A CN 202080040612A CN 113905769 A CN113905769 A CN 113905769A
- Authority
- CN
- China
- Prior art keywords
- polymeric
- poly
- copolymer
- superporous hydrogel
- vinyl ether
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/008—Hydrogels or hydrocolloids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
- C08J9/0061—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof characterized by the use of several polymeric components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0052—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0066—Medicaments; Biocides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
- C08J9/04—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent
- C08J9/06—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a chemical blowing agent
- C08J9/08—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a chemical blowing agent developing carbon dioxide
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L29/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers
- C08L29/02—Homopolymers or copolymers of unsaturated alcohols
- C08L29/04—Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/22—Lipids, fatty acids, e.g. prostaglandins, oils, fats, waxes
- A61L2300/222—Steroids, e.g. corticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/402—Anaestetics, analgesics, e.g. lidocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2203/00—Foams characterized by the expanding agent
- C08J2203/02—CO2-releasing, e.g. NaHCO3 and citric acid
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2205/00—Foams characterised by their properties
- C08J2205/02—Foams characterised by their properties the finished foam itself being a gel or a gel being temporarily formed when processing the foamable composition
- C08J2205/022—Hydrogel, i.e. a gel containing an aqueous composition
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2207/00—Foams characterised by their intended use
- C08J2207/12—Sanitary use, e.g. diapers, napkins or bandages
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2329/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal, or ketal radical; Hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Derivatives of such polymer
- C08J2329/02—Homopolymers or copolymers of unsaturated alcohols
- C08J2329/04—Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2401/00—Characterised by the use of cellulose, modified cellulose or cellulose derivatives
- C08J2401/08—Cellulose derivatives
- C08J2401/26—Cellulose ethers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2435/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical, and containing at least one other carboxyl radical in the molecule, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Derivatives of such polymers
- C08J2435/08—Copolymers with vinyl ethers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/08—Cellulose derivatives
- C08L1/26—Cellulose ethers
- C08L1/28—Alkyl ethers
- C08L1/284—Alkyl ethers with hydroxylated hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L25/00—Compositions of, homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring; Compositions of derivatives of such polymers
- C08L25/02—Homopolymers or copolymers of hydrocarbons
- C08L25/04—Homopolymers or copolymers of styrene
- C08L25/08—Copolymers of styrene
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- C08L33/04—Homopolymers or copolymers of esters
- C08L33/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, which oxygen atoms are present only as part of the carboxyl radical
- C08L33/062—Copolymers with monomers not covered by C08L33/06
- C08L33/064—Copolymers with monomers not covered by C08L33/06 containing anhydride, COOH or COOM groups, with M being metal or onium-cation
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Dispersion Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962832777P | 2019-04-11 | 2019-04-11 | |
| US62/832,777 | 2019-04-11 | ||
| PCT/US2020/027965 WO2020210815A1 (en) | 2019-04-11 | 2020-04-13 | Superporous hydrogels, methods of making the same, and articles incorporating the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113905769A true CN113905769A (zh) | 2022-01-07 |
Family
ID=72748701
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202080040612.7A Pending CN113905769A (zh) | 2019-04-11 | 2020-04-13 | 超多孔水凝胶、其制造方法和包含其的制品 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20200324019A1 (https=) |
| EP (1) | EP3941541B1 (https=) |
| JP (1) | JP2022526185A (https=) |
| CN (1) | CN113905769A (https=) |
| AU (1) | AU2020273195A1 (https=) |
| BR (1) | BR112021020396A2 (https=) |
| CA (1) | CA3136635A1 (https=) |
| CO (1) | CO2021014744A2 (https=) |
| SG (1) | SG11202111268YA (https=) |
| WO (1) | WO2020210815A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117586636A (zh) * | 2023-11-21 | 2024-02-23 | 四川大学 | 水凝胶前驱液及其制备方法、水凝胶及其应用 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USD893514S1 (en) | 2018-11-08 | 2020-08-18 | 11 Health And Technologies Limited | Display screen or portion thereof with graphical user interface |
| AU2021361238A1 (en) | 2020-10-15 | 2023-05-25 | Convatec Technologies Inc. | Ostomy systems and methods |
| KR102534658B1 (ko) * | 2021-09-09 | 2023-05-18 | 김나연 | 폼타입 습윤드레싱용 폼재 제조방법 및 이러한 폼재가 사용된 폼타입 습윤드레싱 |
| CN113978051B (zh) * | 2021-10-28 | 2023-08-04 | 深圳市珂莱蒂尔服饰有限公司 | 一种保暖保温纺织面料及其制备方法 |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5405366A (en) * | 1991-11-12 | 1995-04-11 | Nepera, Inc. | Adhesive hydrogels having extended use lives and process for the preparation of same |
| CN1264321A (zh) * | 1997-05-13 | 2000-08-23 | 普渡研究基金会 | 具有快速溶胀、高机械强度和超吸收特性的水凝胶复合物和超多孔水凝胶复合物 |
| WO2003011352A1 (en) * | 2001-07-26 | 2003-02-13 | Johson & Johson Medical Limited | Apertured sheet materials consisting of a hydrogel composition |
| CN1579559A (zh) * | 2004-05-14 | 2005-02-16 | 中国科学院长春应用化学研究所 | 含药物、壳聚糖的聚乙烯醇水凝胶敷料及其制备方法 |
| CN1960736A (zh) * | 2004-02-27 | 2007-05-09 | 海德罗默公司 | 抗感染水凝胶组合物 |
| US20090306290A1 (en) * | 2004-03-02 | 2009-12-10 | Mircea Dan Bucevschi | Biocompatible, Biodegradable, Water-Absorbent Hybrid Material |
| CN105163768A (zh) * | 2013-02-20 | 2015-12-16 | 开尔弗森2200有限公司 | 抗微生物水凝胶聚合物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9513742D0 (en) * | 1995-07-06 | 1995-09-06 | Smith & Nephew | Compositions |
| JP3773983B2 (ja) * | 1996-03-29 | 2006-05-10 | 日本原子力研究所 | ハイドロゲル創傷被覆材 |
| GB2382305B (en) * | 2001-11-23 | 2004-12-15 | Johnson & Johnson Medical Ltd | Absorbent wound dressings containing a hydrogel layer |
| US20030233649A1 (en) * | 2002-06-14 | 2003-12-18 | Scott Reimert | Maintaining software in computers in a network |
| GB201000879D0 (en) * | 2010-01-20 | 2010-03-10 | Univ Reading The | Improved hydrogel synthesis |
| EP3454839B1 (en) * | 2016-05-12 | 2026-01-28 | Insitu Biologics, Inc. | Hydrogel-based biological delivery vehicle |
| US10881745B2 (en) * | 2017-05-08 | 2021-01-05 | Alivio Therapeutics, Inc. | Formulation of nanostructured gels for increased agent loading and adhesion |
-
2020
- 2020-04-13 CA CA3136635A patent/CA3136635A1/en active Pending
- 2020-04-13 CN CN202080040612.7A patent/CN113905769A/zh active Pending
- 2020-04-13 WO PCT/US2020/027965 patent/WO2020210815A1/en not_active Ceased
- 2020-04-13 BR BR112021020396A patent/BR112021020396A2/pt not_active Application Discontinuation
- 2020-04-13 SG SG11202111268YA patent/SG11202111268YA/en unknown
- 2020-04-13 US US16/847,000 patent/US20200324019A1/en not_active Abandoned
- 2020-04-13 AU AU2020273195A patent/AU2020273195A1/en not_active Abandoned
- 2020-04-13 JP JP2021559925A patent/JP2022526185A/ja active Pending
- 2020-04-13 EP EP20788692.0A patent/EP3941541B1/en active Active
-
2021
- 2021-11-02 CO CONC2021/0014744A patent/CO2021014744A2/es unknown
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5405366A (en) * | 1991-11-12 | 1995-04-11 | Nepera, Inc. | Adhesive hydrogels having extended use lives and process for the preparation of same |
| CN1264321A (zh) * | 1997-05-13 | 2000-08-23 | 普渡研究基金会 | 具有快速溶胀、高机械强度和超吸收特性的水凝胶复合物和超多孔水凝胶复合物 |
| WO2003011352A1 (en) * | 2001-07-26 | 2003-02-13 | Johson & Johson Medical Limited | Apertured sheet materials consisting of a hydrogel composition |
| CN1960736A (zh) * | 2004-02-27 | 2007-05-09 | 海德罗默公司 | 抗感染水凝胶组合物 |
| US20090306290A1 (en) * | 2004-03-02 | 2009-12-10 | Mircea Dan Bucevschi | Biocompatible, Biodegradable, Water-Absorbent Hybrid Material |
| CN1579559A (zh) * | 2004-05-14 | 2005-02-16 | 中国科学院长春应用化学研究所 | 含药物、壳聚糖的聚乙烯醇水凝胶敷料及其制备方法 |
| CN105163768A (zh) * | 2013-02-20 | 2015-12-16 | 开尔弗森2200有限公司 | 抗微生物水凝胶聚合物 |
Non-Patent Citations (3)
| Title |
|---|
| CALO, E等: "Antimicrobial hydrogels based on autoclaved poly(vinyl alcohol) and poly(methyl vinyl ether-alt-maleic anhydride) mixtures for wound care applications", 《 RSC ADVANCES》 * |
| DEMIR, YK等: "Poly (methyl vinyl ether-co-maleic acid) - Pectin based hydrogel-forming systems: Gel, film, and microneedles", 《 EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS》 * |
| ENRICA CALÓ: "Developing new interface materials for wound care applications", 《SUBMITTED AS PARTIAL FULFILMENT FOR THE DEGREE OF DOCTOR OF PHILOSOPHY》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117586636A (zh) * | 2023-11-21 | 2024-02-23 | 四川大学 | 水凝胶前驱液及其制备方法、水凝胶及其应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| SG11202111268YA (en) | 2021-11-29 |
| BR112021020396A2 (pt) | 2021-12-07 |
| EP3941541A4 (en) | 2022-05-11 |
| EP3941541C0 (en) | 2024-03-20 |
| JP2022526185A (ja) | 2022-05-23 |
| CO2021014744A2 (es) | 2022-02-28 |
| EP3941541B1 (en) | 2024-03-20 |
| EP3941541A1 (en) | 2022-01-26 |
| US20200324019A1 (en) | 2020-10-15 |
| CA3136635A1 (en) | 2020-10-15 |
| AU2020273195A1 (en) | 2021-11-04 |
| WO2020210815A1 (en) | 2020-10-15 |
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