CN113891747A - 诱导免疫细胞活性的组合物及使用该组合物治疗疾病的方法 - Google Patents
诱导免疫细胞活性的组合物及使用该组合物治疗疾病的方法 Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/763—Herpes virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Abstract
一种在有需要的受试者中诱导免疫细胞活性的组合物,其包含与所述受试者自体同源的肿瘤细胞裂解物、OX40激动剂和TLR激动剂。使用所述组合物用于治疗受试者病症的方法。
Description
PCT国内申请,说明书已公开。
Claims (35)
- PCT国内申请,权利要求书已公开。
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CN107001478A (zh) * | 2014-10-14 | 2017-08-01 | 诺华股份有限公司 | 针对pd‑l1的抗体分子及其用途 |
CN108135934A (zh) * | 2015-10-19 | 2018-06-08 | 永恒生物科技股份有限公司 | 通过组合疗法治疗实体或淋巴肿瘤的方法 |
WO2018127713A1 (en) * | 2017-01-09 | 2018-07-12 | Replimune Limited | Altered virus |
CN108289858A (zh) * | 2015-06-30 | 2018-07-17 | 宾夕法尼亚州立大学托管会 | 用于治疗肿瘤性皮肤疾病的瑞喹莫特局部可注射组合物 |
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WO2014022138A2 (en) * | 2012-07-30 | 2014-02-06 | Alex Wah Hin Yeung | Live and in-vivo tumor specific cancer vaccine system developed by co-administration of either at least two or all three of the following components such as tumor cells, an oncolytic virus vector with transgenic expression of gm-csf and an immune checkpoint modulator |
TW201716084A (zh) * | 2015-08-06 | 2017-05-16 | 葛蘭素史克智慧財產發展有限公司 | 組合物及其用途與治療 |
JP7410472B2 (ja) * | 2015-09-25 | 2024-01-10 | リリース セラピューティクス エスアー | 免疫調節物質を産生する免疫隔離細胞とのワクチン接種 |
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