CN113876884A - Medicinal composition for prolonging life and preparation method and application thereof - Google Patents

Medicinal composition for prolonging life and preparation method and application thereof Download PDF

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Publication number
CN113876884A
CN113876884A CN202111306755.0A CN202111306755A CN113876884A CN 113876884 A CN113876884 A CN 113876884A CN 202111306755 A CN202111306755 A CN 202111306755A CN 113876884 A CN113876884 A CN 113876884A
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parts
radix
pharmaceutical composition
wine
fructus
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何必华
乔志乾
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Hangzhou Zhongyong Human Resources Service Co ltd
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Hangzhou Zhongyong Human Resources Service Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/586Turtles; Tortoises, e.g. terrapins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237Notopterygium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/40Cornaceae (Dogwood family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G3/00Preparation of other alcoholic beverages
    • C12G3/04Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
    • C12G3/05Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs with health-improving ingredients, e.g. flavonoids, flavones, polyphenols or polysaccharides
    • C12G3/055Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs with health-improving ingredients, e.g. flavonoids, flavones, polyphenols or polysaccharides extracted from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

Abstract

The invention discloses a pharmaceutical composition for prolonging life, a preparation method and application thereof, wherein the pharmaceutical composition comprises: radix astragali, Poria, rhizoma Atractylodis Macrocephalae, radix rehmanniae Preparata, radix Angelicae sinensis, radix rehmanniae, radix Codonopsis, radix Ophiopogonis, pericarpium Citri Reticulatae, fructus Corni preparata, rhizoma Et radix Notopterygii, fructus Lycii, cortex Cinnamomi, rhizoma Chuanxiong, radix Saposhnikoviae, fructus Schisandrae chinensis, colla Plastri Testudinis, and fructus Jujubae. The invention also provides application of the pharmaceutical composition, and the composition is used for preparing medicinal liquor. The invention also provides a method for preparing medicinal liquor by using the medicinal composition and the prepared medicinal liquor. The medicinal liquor prepared from the medicinal composition has the effects of resisting premature senility and prolonging life, can be widely applied to prevention and treatment of various chronic consumptive disease, and also has the effects of resisting aging and prolonging life.

Description

Medicinal composition for prolonging life and preparation method and application thereof
Technical Field
The invention relates to a composition, a preparation method and application thereof, in particular to a medicinal composition for prolonging life and a preparation method and application thereof.
Background
The wine is called as 'the best of all drugs', the medicinal liquor which integrates the traditional Chinese medicines for strengthening the body and the wine is convenient to prepare, stable in medicine property, safe and effective, and various active ingredients of the traditional Chinese medicines are easily dissolved in the wine because the alcohol is a good semipolar organic solvent, so that the efficacy of the traditional Chinese medicines is fully exerted by the aid of the wine power and the wine assistant medicine potential, and the curative effect is improved.
The wine and the medical element are not understood, the traditional Chinese medicine character is from 'unitary', and the unitary wine is also used. This is probably because ancestors accidentally eat fermented melon and fruit juice, which was found to treat some diseases such as cold and abdominal pain, and thus the wine is a source of original medical activities. The Huangdi's classic has the treatise on herb liquor with amazalin, which is a special discussion of the way of taking medicine. The so-called "decoction" is the decoction of modern times, while "amazalin" is the medicated wine. Obviously, the medical function of the medicinal liquor has been deeply known in the era of war country.
The main component ethanol (commonly called alcohol) of the wine is a good semi-polar organic solvent, and many medicines of which the effective components are difficult to separate out by other processing methods can be extracted by the characteristic of the wine. Various components of Chinese medicinal materials such as alkaloid, salt, tannin, volatile oil, organic acid, resin, saccharide and part of pigment (such as chlorophyll and xanthophyll) are easily dissolved in ethanol. The ethanol has good penetrability, is easy to enter medicinal material histiocyte, plays a role in dissolving, promotes replacement and diffusion, and is beneficial to improving the leaching speed and the leaching effect; also has antiseptic effect, and can delay hydrolysis of many drugs and enhance stability of the preparation.
However, the compatibility of materials of the medicinal liquor is more, and the materials are different in tissue structure and chemical components, so that the functional and curative effects of the materials are excluded when the materials are directly taken into the formula. The curative effect of the medicinal liquor is easily reduced, even the components are chemically changed and converted into toxic and harmful substances, which have negative effects on human bodies and threaten health.
Disclosure of Invention
The invention aims to provide a composition, a preparation method and application thereof, which are used for preparing medicinal liquor, can solve the existing problems and fully exert the effects of preventing and treating diseases and prolonging life.
In order to achieve the above objects, the present invention provides a life-prolonging pharmaceutical composition, wherein the composition comprises: radix astragali, Poria, rhizoma Atractylodis Macrocephalae, radix rehmanniae Preparata, radix Angelicae sinensis, radix rehmanniae, radix Codonopsis, radix Ophiopogonis, pericarpium Citri Reticulatae, fructus Corni preparata, rhizoma Et radix Notopterygii, fructus Lycii, cortex Cinnamomi, rhizoma Chuanxiong, radix Saposhnikoviae, fructus Schisandrae chinensis, colla Plastri Testudinis, and fructus Jujubae.
The life-prolonging pharmaceutical composition comprises the following components in parts by weight: 10-15 parts of astragalus membranaceus, 16-20 parts of poria with hostwood, 5-8 parts of raw bighead atractylodes rhizome, 6-10 parts of prepared rehmannia root, 6-10 parts of angelica sinensis, 6-10 parts of radix rehmanniae recen, 5-8 parts of codonopsis pilosula, 5-8 parts of radix ophiopogonis, 5-8 parts of dried orange peel, 5-8 parts of dogwood fruit wine, 4-6 parts of notopterygium root, 5-8 parts of wolfberry fruit, 3-5 parts of cinnamon, 5-8 parts of ligusticum wallichii, 5-8 parts of divaricate saposhnikovia root, 4-6 parts of schisandra chinensis, 5-8 parts of tortoise-plastron glue and 50-70 parts of red date.
The life-prolonging pharmaceutical composition comprises the following components in parts by weight: 12g of astragalus, 18g of poria with hostwood, 6g of raw bighead atractylodes rhizome, 8g of prepared rehmannia root, 8g of Chinese angelica, 8g of radix rehmanniae recen, 6g of codonopsis pilosula, 6g of radix ophiopogonis, 6g of dried orange peel, 6g of wine pulp of dogwood fruit, 5g of notopterygium root, 6g of wolfberry fruit, 4g of cinnamon, 6g of ligusticum wallichii, 6g of divaricate saposhnikovia root, 5g of schisandra chinensis, 6g of tortoise plastron glue and 9 red dates, wherein each 6g of red dates are added.
The invention also provides application of the pharmaceutical composition, wherein the composition is used for preparing medicinal liquor.
The invention also provides a method for preparing medicinal liquor by using the medicinal composition, wherein the method comprises the following steps: weighing the medicinal materials in proportion, slicing the solid medicinal materials respectively, adding the solid medicinal materials and other components into wine, and soaking for one week at normal temperature for drinking.
The method for preparing the medicinal liquor by using the medicinal composition is characterized in that the medicinal liquor is sorghum liquor.
The life-prolonging pharmaceutical composition is characterized in that the weight ratio of the sorghum liquor to the total amount of the pharmaceutical composition is 50: (3-4).
The invention also provides the medicinal liquor prepared by the method, wherein the medicinal liquor is health-care medicinal liquor for prolonging life and enhancing physique.
The medicinal composition for prolonging the life, the preparation method and the application thereof provided by the invention have the following advantages:
the medicinal composition for prolonging the life provided by the invention adopts a plurality of tonifying medicaments, has the efficacies of resisting premature senility and prolonging the life, can be widely applied to the prevention and treatment of various chronic consumptive disease, and also can resist aging and prolong the life.
The invention can be used for treating deficiency of both qi and blood, such as tiredness, listlessness, palpitation, dizziness, blurred vision, amnesia, insomnia and other diseases. The traditional Chinese medicine composition has the advantages of simple preparation and taking, stable medicine property, safety and effectiveness, and can fully exert the efficacy and improve the curative effect due to the effect of the medicine on the wine and the efficacy of the wine, thereby achieving the effects of enhancing the resistance and prolonging the service life.
Detailed Description
The following further describes embodiments of the present invention.
The invention provides a life-prolonging pharmaceutical composition, which comprises: radix astragali, Poria, rhizoma Atractylodis Macrocephalae, radix rehmanniae Preparata, radix Angelicae sinensis, radix rehmanniae, radix Codonopsis, radix Ophiopogonis, pericarpium Citri Reticulatae, fructus Corni preparata, rhizoma Et radix Notopterygii, fructus Lycii, cortex Cinnamomi, rhizoma Chuanxiong, radix Saposhnikoviae, fructus Schisandrae chinensis, colla Plastri Testudinis, and fructus Jujubae.
Wherein the radix astragali is root of Astragalus membranaceus bge of Leguminosae. Digging in spring and autumn, removing soil, fibrous root and root head, drying in the sun to six or seven percent, straightening, bundling and drying in the sun. Has sweet and mild nature and taste, enters lung, spleen, liver and kidney meridians, has effects of enhancing organism immunity, protecting liver, promoting urination, resisting aging, resisting stress, lowering blood pressure and broad antibacterial action, and can be used for enhancing immunity.
Poria is white part of Poria cocos sclerotia (Poria cocos) of Polyporaceae with pine root (Poria cocos Woods) in the middle. The dried sclerotium has the same shape as Poria, but has a pine root penetrating through the middle part. The product is mostly cut into square thin slices, the product is firm and powdery, the cut pine roots are brownish yellow, and the surface has ring-shaped textures (annual rings). The interior is thick and the pine root is small. Sweet and bland in nature and taste. Enter heart and spleen meridians. The main functional indications are as follows: tranquilize the heart, induce tranquilization and induce diuresis. It is indicated for palpitation, amnesia, insomnia, fright epilepsy and dysuria due to heart deficiency.
The rhizoma Atractylodis Macrocephalae is dried rhizome of Atractylodes macrocephala Koidz of Compositae. Atractylodis rhizoma belongs to Compositae and Atractylodes perennial herb, and is used as Chinese medicinal material, collected by downing to winter, removed stem and leaf and soil, oven-dried or sun-dried, and removed fibrous root. Bitter and sweet taste, warm nature; spleen and stomach meridians entered; has effects in invigorating spleen, invigorating qi, eliminating dampness, promoting diuresis, arresting sweating, and preventing miscarriage; can be used for treating spleen deficiency, anorexia, abdominal distention, diarrhea, phlegm retention, dizziness, palpitation, edema, spontaneous perspiration, and threatened abortion.
The radix rehmanniae Preparata is rhizome of Scrophulariaceae plant rehmanniae radix or rehmanniae radix, and is prepared by processing, steaming and drying. Sweet and mild in nature and taste, enters liver and kidney meridians, and has effects of replenishing blood and yin, replenishing essence and marrow, and can be used for treating deficiency of liver-yin and kidney-yin, soreness and weakness of waist and knees, hectic fever due to yin deficiency, night sweat and nocturnal emission, internal heat, diabetes, blood deficiency, sallow complexion, cardiopalmus, palpitation, menoxenia, metrorrhagia, metrostaxis, tinnitus, and premature gray hair.
The radix Angelicae sinensis is dried root of Angelica sinensis (oliv.) Diels of Umbelliferae. Collected in late autumn, removed the reed heads and fibrous roots, and bundled into small bundles according to size and thickness after water is slightly evaporated, and then slowly smoked to dry with slow fire or smoked with sulfur, sliced for use, or mixed with wine and parched with wine. Sweet, slightly bitter, slightly numb and pungent taste, sweet and pungent taste, warm nature. It enters liver, heart and spleen meridians. Has effects in replenishing blood, promoting blood circulation, regulating menstruation, relieving pain, loosening bowel to relieve constipation, resisting cancer, resisting aging, and enhancing immunity. It can be used for treating blood deficiency, sallow complexion, giddiness, palpitation, menoxenia, amenorrhea, dysmenorrhea, asthenia cold, abdominal pain, rheumatalgia, traumatic injury, superficial infection, pyocutaneous disease, intestinal dryness, and constipation. Can be used for promoting blood circulation, removing blood stasis, and relieving constipation.
Radix rehmanniae is also called as Ye Di Huang, shan Yan Gen, etc., and is the root tuber of rehmannia glutinosa Libosch of Scrophulariaceae. Sweet, bitter and cold in nature and taste; it enters heart, liver and kidney meridians. Has the effects of clearing heat, cooling blood, nourishing yin and promoting the production of body fluid. Can be used for treating heat entering nutrient-blood, crimson tongue with polydipsia, macula, hematemesis and epistaxis, yin deficiency with internal heat, bone steaming with internal heat, body fluid consumption with thirst, internal heat with diabetes, intestinal dryness with constipation.
The radix Codonopsis is dried root of radix Codonopsis, radix Codonopsis Lanceolatae or radix Codonopsis Pilosulae of Campanulaceae. Sweet and mild in nature and taste, has the effects of invigorating spleen and replenishing qi, regulating stomach function and promoting fluid production, eliminating phlegm and relieving cough, and is used for treating spleen deficiency, anorexia, loose stool, myasthenia of limbs, palpitation, short breath, dry mouth, spontaneous perspiration, rectocele, and abnormal yin, and invigorating primordial qi.
Radix Ophiopogonis is dried root tuber of Ophiopogon japonicus (Thunb.) Ker.) Gawl.) of Liliaceae. Sweet in nature, slightly bitter and slightly cold in nature. It enters heart, lung and stomach meridians. Can be used for treating deficiency of body fluid, thirst, dry cough, and hemoptysis due to yin deficiency of lung and stomach; palpitation due to heart yin deficiency and fluid impairment due to heat in the late stage of fever. Has effects in nourishing yin, moistening lung, benefiting stomach, promoting fluid production, clearing heart fire, and relieving restlessness, and can be used for treating dry cough due to lung dryness, tuberculosis cough due to yin deficiency, pharyngitis, pharyngalgia, body fluid injury, thirst, internal heat, diabetes, vexation, insomnia, and constipation due to intestinal dryness, and moistening lung.
The pericarpium Citri Tangerinae is dried mature pericarp of Rutaceae plant fructus Citri Tangerinae and its cultivar; picking mature fruit, peeling peel, and drying in the sun or at low temperature. Bitter and pungent taste, warm in nature; entering lung and spleen meridians; has the effects of regulating qi, strengthening spleen, eliminating dampness and phlegm; it can be used for treating abdominal distention, anorexia, vomiting, diarrhea, cough, and excessive phlegm; it is combined with cang Zhu and Hou Po to treat gastric and abdominal distention and pain, nausea, vomiting and diarrhea due to cold-dampness in middle energizer and qi stagnation in spleen and stomach.
Wine and fructus Corni the product is dried mature pulp of fructus Corni of Cornaceae. Collecting fruit when pericarp turns red in late autumn and early winter, baking with slow fire or slightly scalding in boiling water, removing fruit core in time, and drying. Mixing with yellow wine, placing in a pot or other container, sealing, steaming in a pot with water until the wine is absorbed completely, taking out, and air drying. Sour, astringent and slightly warm in nature and taste. It enters liver and kidney meridians. Can be used for treating soreness of waist and knees, vertigo, tinnitus, sexual impotence, spermatorrhea, frequent micturition, liver deficiency, cold and heat, sweating, and heart shaking pulse powder.
Notopterygii rhizoma is dried root of Notopterygii rhizoma of Umbelliferae; pungent and bitter taste, warm nature; entering bladder and kidney meridians; has the effects of relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, eliminating dampness, and relieving pain; can be used for treating wind-cold type common cold, arthralgia due to wind-cold-dampness, neck stiffness, spasm of muscles, soreness of bone joints, edema due to wind-cold, superficial infection, and skin sore.
Fructus Lycii is mature fruit of Solanaceae plant fructus Lycii or Ningxia fructus Lycii. Picking in summer and autumn when the fruit is ripe, removing fruit stalks, drying in the shade until the peel wrinkles, and insolating until the outer skin is dry and hard and the pulp is soft. Drying with slow fire in rainy days. Sweet in nature and taste and mild in nature. Enter liver and kidney meridians. Has effects of nourishing kidney, moistening lung, nourishing liver, and improving eyesight. Can be used for treating yin deficiency of liver and kidney, soreness of waist and knees, dizziness, blurred vision, hyperdacryosis, cough due to asthenia, diabetes, and spermatorrhea.
Cinnamon is the dried bark of cinnamon belonging to the family Lauraceae. Pungent and sweet in flavor and strongly hot in nature. It enters kidney, spleen, heart and liver meridians. Has the effects of supplementing fire and supporting yang, guiding fire to the origin, dispelling cold and relieving pain, and warming and dredging channels and collaterals. Can be used for treating sexual impotence, cold womb, cold pain of waist and knee, asthma due to kidney deficiency, floating of deficient yang, giddiness, conjunctival congestion, cold pain of heart and abdomen, vomiting and diarrhea due to deficiency cold, cold hernia, abdominal pain, dysmenorrhea, and amenorrhea.
Rhizoma Ligustici Chuanxiong is dried rhizome of Umbelliferae plant rhizoma Ligustici Chuanxiong; digging in 5 months, removing silt, drying in the sun, and removing fibrous root. Sliced, unprocessed or stir-baked with wine. Pungent and warm in nature and taste; entering liver, gallbladder and pericardium; has the effects of promoting qi circulation, resolving stagnation, dispelling pathogenic wind, eliminating dampness, promoting blood circulation, and relieving pain; it can be used for treating wind-cold headache, vertigo, hypochondriac pain, abdominal pain, cold arthralgia, spasm of tendons, amenorrhea, dystocia, puerperal stagnation, pain, carbuncle, cellulitis, and pyocutaneous disease. Can be used for treating menoxenia, amenorrhea, dysmenorrhea, abdominal pain, pricking pain in chest and hypochondrium, traumatic injury, swelling and pain, headache, and rheumatalgia.
Radix Saposhnikoviae is root of radix Saposhnikoviae belonging to family Umbelliferae. Perennial herbaceous plants like cool climate, cold resistance and drought resistance, and are mainly produced in Hebei, Heilongjiang, Sichuan, inner Mongolia and other places. Unprocessed Fang Feng Gen. Pungent and sweet in flavor, slightly warm in nature. It enters bladder, lung, spleen and liver meridians. Has the effects of dispelling pathogenic wind, relieving exterior syndrome, eliminating dampness, relieving pain, and relieving spasm. Can be used for treating exterior syndrome due to exogenous pathogenic factor, rubella pruritus, rheumatalgia, tetanus, and spleen deficiency with excessive dampness.
The northern schisandra chinensis is distributed in the north of the yellow river basin, mainly in the northeast and north China, including Heilongjiang, Jilin, Liaoning, inner Mongolia, Hebei, Shanxi, Ningxia, Gansu and Shandong, wherein the northeast is the most concentrated area of the schisandra chinensis. Dried schisandra chinensis which is mainly produced in northeast and Hebei and the like, and the commercial habit is called as 'northern schisandra chinensis'. Fructus Schisandrae is mature fruit of Magnoliaceae fructus Schisandrae chinensis or Schisandra sphenanthera. Collected in autumn when the fruit is ripe, dried in the sun. Unprocessed or mixed with vinegar and honey, steamed and dried in the sun. Sour, sweet and warm in nature; it enters lung, heart and kidney meridians. Has effects of astringing, arresting discharge, invigorating qi, promoting fluid production, invigorating kidney, and calming heart. Can be used for treating chronic cough, asthma, spontaneous perspiration, night sweat, spermatorrhea, chronic diarrhea, thirst due to body fluid consumption, palpitation, insomnia, and dreaminess.
The colla Plastri Testudinis is comprises carapax et Plastrum Testudinis as main ingredient and yellow wine as adjuvant. The product is rectangular flat block, dark brown, hard and brittle, and has bright cross section and transparent shape for illumination; slight fishy smell and bland taste. Nourish yin, nourish blood. Can be used for treating hectic fever due to yin deficiency, hectic fever, night sweat, soreness of waist and knees, and sallow complexion due to blood deficiency.
Fructus Jujubae is fructus Jujubae, and is the mature fruit of Zizyphi fructus of Rhamnaceae. Becomes red after maturation. Dried dates are prepared by drying in the sun. It has very high vitamin content, is reputed as natural vitamin pill, and has the functions of nourishing Yin and invigorating Yang. The red date is used as a good nourishing product, can be used for medicine, has the effects of nourishing the stomach, tonifying the spleen, benefiting the blood, nourishing and strengthening the body, can be used as medicines for both the kernel and the root of the red date, can soothe the nerves, and is one of important medicines. Sweet taste and warm nature; it enters spleen, stomach and heart meridians. Has effects of invigorating spleen, replenishing qi, nourishing blood, and tranquilizing. It is indicated for spleen deficiency syndrome, irritability and insomnia.
Preferably, the composition comprises, in parts by weight: 10-15 parts of astragalus membranaceus, 16-20 parts of poria with hostwood, 5-8 parts of raw bighead atractylodes rhizome, 6-10 parts of prepared rehmannia root, 6-10 parts of angelica sinensis, 6-10 parts of radix rehmanniae recen, 5-8 parts of codonopsis pilosula, 5-8 parts of radix ophiopogonis, 5-8 parts of dried orange peel, 5-8 parts of dogwood fruit wine, 4-6 parts of notopterygium root, 5-8 parts of wolfberry fruit, 3-5 parts of cinnamon, 5-8 parts of ligusticum wallichii, 5-8 parts of divaricate saposhnikovia root, 4-6 parts of schisandra chinensis, 5-8 parts of tortoise-plastron glue and 50-70 parts of red date.
More preferably, the composition comprises by weight: 12g of astragalus, 18g of poria with hostwood, 6g of raw bighead atractylodes rhizome, 8g of prepared rehmannia root, 8g of Chinese angelica, 8g of radix rehmanniae recen, 6g of codonopsis pilosula, 6g of radix ophiopogonis, 6g of dried orange peel, 6g of wine pulp of dogwood fruit, 5g of notopterygium root, 6g of wolfberry fruit, 4g of cinnamon, 6g of ligusticum wallichii, 6g of divaricate saposhnikovia root, 5g of schisandra chinensis, 6g of tortoise plastron glue and 9 red dates, wherein each 6g of red dates are added.
The invention also provides application of the pharmaceutical composition, and the composition is used for preparing medicinal liquor.
The invention also provides a method for preparing medicinal liquor by using the medicinal composition, which comprises the following steps: weighing the medicinal materials in proportion, slicing the solid medicinal materials respectively, adding the solid medicinal materials and other components into wine, and soaking for one week at normal temperature for drinking.
The liquor is sorghum liquor.
The weight ratio of the sorghum liquor to the total amount of the pharmaceutical composition is 50: (3-4).
The invention also provides the medicinal liquor prepared by the method, and the medicinal liquor is health-care medicinal liquor for prolonging life and enhancing physique.
The life prolonging pharmaceutical composition, the preparation method and the use thereof provided by the invention are further described below with reference to the examples.
Example 1
A life-prolonging pharmaceutical composition comprising: radix astragali, Poria, rhizoma Atractylodis Macrocephalae, radix rehmanniae Preparata, radix Angelicae sinensis, radix rehmanniae, radix Codonopsis, radix Ophiopogonis, pericarpium Citri Reticulatae, fructus Corni preparata, rhizoma Et radix Notopterygii, fructus Lycii, cortex Cinnamomi, rhizoma Chuanxiong, radix Saposhnikoviae, fructus Schisandrae chinensis, colla Plastri Testudinis, and fructus Jujubae.
Preferably, the composition comprises by weight: 12g of astragalus, 18g of poria with hostwood, 6g of raw bighead atractylodes rhizome, 8g of prepared rehmannia root, 8g of Chinese angelica, 8g of radix rehmanniae recen, 6g of codonopsis pilosula, 6g of radix ophiopogonis, 6g of dried orange peel, 6g of wine pulp of dogwood fruit, 5g of notopterygium root, 6g of wolfberry fruit, 4g of cinnamon, 6g of ligusticum wallichii, 6g of divaricate saposhnikovia root, 5g of schisandra chinensis, 6g of tortoise plastron glue and 9 red dates, wherein each 6g of red dates are added.
The embodiment also provides the application of the pharmaceutical composition, and the composition is used for preparing medicinal liquor.
The embodiment also provides a method for preparing medicinal liquor by using the medicinal composition, which comprises the following steps: weighing the medicinal materials in proportion, slicing the solid medicinal materials respectively, adding the solid medicinal materials and other components into wine, and soaking for one week at normal temperature for drinking. The liquor is sorghum liquor. The dosage of the sorghum liquor is 5 jin, namely 2500 g.
The embodiment also provides the medicinal liquor prepared by the method, and the medicinal liquor is health-care medicinal liquor for prolonging life and enhancing physique.
Example 2
A life-prolonging pharmaceutical composition comprising: radix astragali, Poria, rhizoma Atractylodis Macrocephalae, radix rehmanniae Preparata, radix Angelicae sinensis, radix rehmanniae, radix Codonopsis, radix Ophiopogonis, pericarpium Citri Reticulatae, fructus Corni preparata, rhizoma Et radix Notopterygii, fructus Lycii, cortex Cinnamomi, rhizoma Chuanxiong, radix Saposhnikoviae, fructus Schisandrae chinensis, colla Plastri Testudinis, and fructus Jujubae.
Preferably, the composition comprises, in parts by weight: 15 parts of astragalus, 20 parts of poria with hostwood, 8 parts of raw bighead atractylodes rhizome, 10 parts of prepared rehmannia root, 10 parts of angelica, 10 parts of radix rehmanniae recen, 8 parts of codonopsis pilosula, 8 parts of radix ophiopogonis, 8 parts of dried orange peel, 8 parts of wine cornus, 6 parts of notopterygium root, 8 parts of wolfberry fruit, 5 parts of cinnamon, 8 parts of ligusticum wallichii, 8 parts of divaricate saposhnikovia root, 6 parts of schisandra chinensis, 8 parts of tortoise glue and 70 parts of red date.
The embodiment also provides the application of the pharmaceutical composition, and the composition is used for preparing medicinal liquor.
The embodiment also provides a method for preparing medicinal liquor by using the medicinal composition, which comprises the following steps: weighing the medicinal materials in proportion, slicing the solid medicinal materials respectively, adding the solid medicinal materials and other components into wine, and soaking for one week at normal temperature for drinking. The liquor is sorghum liquor. The weight ratio of the sorghum liquor to the total amount of the pharmaceutical composition is 50: 3.
The embodiment also provides the medicinal liquor prepared by the method, and the medicinal liquor is health-care medicinal liquor for prolonging life and enhancing physique.
Example 3
A life-prolonging pharmaceutical composition comprising: radix astragali, Poria, rhizoma Atractylodis Macrocephalae, radix rehmanniae Preparata, radix Angelicae sinensis, radix rehmanniae, radix Codonopsis, radix Ophiopogonis, pericarpium Citri Reticulatae, fructus Corni preparata, rhizoma Et radix Notopterygii, fructus Lycii, cortex Cinnamomi, rhizoma Chuanxiong, radix Saposhnikoviae, fructus Schisandrae chinensis, colla Plastri Testudinis, and fructus Jujubae.
Preferably, the composition comprises, in parts by weight: 10 parts of astragalus, 16 parts of poria with hostwood, 5 parts of raw bighead atractylodes rhizome, 6 parts of prepared rehmannia root, 6 parts of Chinese angelica, 6 parts of radix rehmanniae recen, 5 parts of codonopsis pilosula, 5 parts of radix ophiopogonis, 5 parts of dried orange peel, 5 parts of wine cornus, 4 parts of notopterygium root, 5 parts of wolfberry fruit, 3 parts of cinnamon, 5 parts of ligusticum wallichii, 5 parts of divaricate saposhnikovia root, 4 parts of schisandra chinensis, 5 parts of tortoise plastron glue and 50 parts of red date.
More preferably, the composition comprises by weight: 12g of astragalus, 18g of poria with hostwood, 6g of raw bighead atractylodes rhizome, 8g of prepared rehmannia root, 8g of Chinese angelica, 8g of radix rehmanniae recen, 6g of codonopsis pilosula, 6g of radix ophiopogonis, 6g of dried orange peel, 6g of wine pulp of dogwood fruit, 5g of notopterygium root, 6g of wolfberry fruit, 4g of cinnamon, 6g of ligusticum wallichii, 6g of divaricate saposhnikovia root, 5g of schisandra chinensis, 6g of tortoise plastron glue and 9 red dates, wherein each 6g of red dates are added.
The embodiment also provides the application of the pharmaceutical composition, and the composition is used for preparing medicinal liquor.
The embodiment also provides a method for preparing medicinal liquor by using the medicinal composition, which comprises the following steps: weighing the medicinal materials in proportion, slicing the solid medicinal materials respectively, adding the solid medicinal materials and other components into wine, and soaking for one week at normal temperature for drinking. The liquor is sorghum liquor. The weight ratio of the sorghum liquor to the total amount of the pharmaceutical composition is 50: 4.
The embodiment also provides the medicinal liquor prepared by the method, and the medicinal liquor is health-care medicinal liquor for prolonging life and enhancing physique.
However, chronic diseases with deep and long-term illness often cause deficiency of qi, blood, yin and yang of human body, and the formation of the chronic diseases is not one day, so that the treatment and recovery are difficult to do once you kick on the article, and generally a process is needed. Various chronic deficiency diseases often have unsmooth qi and blood and unsmooth channels and collaterals in different degrees, and the treatment is often assisted by medicines for promoting blood circulation and removing meridian obstruction to enhance the curative effect.
The medicinal liquor is prepared from the medicinal composition, and by utilizing the characteristics of warm nature, pungent and bitter taste and sweet taste of the sorghum liquor, and the effects of warming and activating blood vessels, diffusing medicinal efficacy, warming intestines and stomach, dispelling wind cold, exciting yang qi, eliminating fatigue and the like, the main compatibility is the nourishing medicament with the effects of tonifying qi, enriching blood, nourishing yin and warming yang, so that the medicinal liquor is more beneficial to the treatment of chronic diseases, the medicaments are purposefully combined according to the reasonable tissue structures of monarch, minister, assistant and guide, the medicaments in the formula and the compatibility thereof are screwed into the pathogenic filaments of diseases, and the comprehensive effect after the medicaments are combined is highly unified with the established treatment method. The human body can regulate qi and blood and the noble metal can regulate the flow of qi and blood. If the blood is tonified but unable to circulate, the benefit of tonifying cannot be obtained, so the stasis will be overcome. While the defensive qi of the drinker firstly develops the skin, and fills the channels and collaterals, so the defensive qi is flat, the nutritive qi is full, and the channels and collaterals are profuse.
The medicinal composition for prolonging the life, the preparation method and the application thereof adopt a plurality of tonifying medicaments, have the efficacies of resisting premature senility and prolonging the life, can be widely applied to the prevention and treatment of various chronic consumptive disease, and also can resist aging and prolong the life.
While the present invention has been described in detail with reference to the preferred embodiments, it should be understood that the above description should not be taken as limiting the invention. Various modifications and alterations to this invention will become apparent to those skilled in the art upon reading the foregoing description. Accordingly, the scope of the invention should be determined from the following claims.

Claims (8)

1. A life-prolonging pharmaceutical composition, comprising: radix astragali, Poria, rhizoma Atractylodis Macrocephalae, radix rehmanniae Preparata, radix Angelicae sinensis, radix rehmanniae, radix Codonopsis, radix Ophiopogonis, pericarpium Citri Reticulatae, fructus Corni preparata, rhizoma Et radix Notopterygii, fructus Lycii, cortex Cinnamomi, rhizoma Chuanxiong, radix Saposhnikoviae, fructus Schisandrae chinensis, colla Plastri Testudinis, and fructus Jujubae.
2. The life prolonging pharmaceutical composition according to claim 1, wherein the composition comprises in parts by weight: 10-15 parts of astragalus membranaceus, 16-20 parts of poria with hostwood, 5-8 parts of raw bighead atractylodes rhizome, 6-10 parts of prepared rehmannia root, 6-10 parts of angelica sinensis, 6-10 parts of radix rehmanniae recen, 5-8 parts of codonopsis pilosula, 5-8 parts of radix ophiopogonis, 5-8 parts of dried orange peel, 5-8 parts of dogwood fruit wine, 4-6 parts of notopterygium root, 5-8 parts of wolfberry fruit, 3-5 parts of cinnamon, 5-8 parts of ligusticum wallichii, 5-8 parts of divaricate saposhnikovia root, 4-6 parts of schisandra chinensis, 5-8 parts of tortoise-plastron glue and 50-70 parts of red date.
3. The life prolonging pharmaceutical composition of claim 2, wherein said composition comprises by weight: 12g of astragalus, 18g of poria with hostwood, 6g of raw bighead atractylodes rhizome, 8g of prepared rehmannia root, 8g of Chinese angelica, 8g of radix rehmanniae recen, 6g of codonopsis pilosula, 6g of radix ophiopogonis, 6g of dried orange peel, 6g of wine pulp of dogwood fruit, 5g of notopterygium root, 6g of wolfberry fruit, 4g of cinnamon, 6g of ligusticum wallichii, 6g of divaricate saposhnikovia root, 5g of schisandra chinensis, 6g of tortoise plastron glue and 9 red dates, wherein each 6g of red dates are added.
4. Use of a pharmaceutical composition according to any one of claims 1 to 3 for the preparation of a medicated wine.
5. A method of using the pharmaceutical composition of claim 4 for the preparation of a medicated wine, said method comprising: weighing the medicinal materials in proportion, slicing the solid medicinal materials respectively, adding the solid medicinal materials and other components into wine, and soaking for one week at normal temperature for drinking.
6. The method for preparing medicated wine from the pharmaceutical composition according to claim 5, wherein the wine is kaoliang spirit.
7. The life prolonging pharmaceutical composition of claim 6, wherein the weight ratio of the kaoliang spirit to the total amount of the pharmaceutical composition is 50: (3-4).
8. A medicated wine prepared by the method of claim 5, wherein the medicated wine is a health medicated wine for prolonging life and strengthening physique.
CN202111306755.0A 2021-11-05 2021-11-05 Medicinal composition for prolonging life and preparation method and application thereof Pending CN113876884A (en)

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Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
张保国: "《精选男性药酒1200例》", 13 May 2013, 中国医药科技出版社 *

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