CN113876363B - Special sampling brush in oral cavity - Google Patents

Special sampling brush in oral cavity Download PDF

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Publication number
CN113876363B
CN113876363B CN202111150132.9A CN202111150132A CN113876363B CN 113876363 B CN113876363 B CN 113876363B CN 202111150132 A CN202111150132 A CN 202111150132A CN 113876363 B CN113876363 B CN 113876363B
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China
Prior art keywords
sampling
brush
sampling tube
preparation
block
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CN202111150132.9A
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CN113876363A (en
Inventor
冯敏
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West China Second University Hospital of Sichuan University
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West China Second University Hospital of Sichuan University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B2010/0216Sampling brushes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E60/00Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
    • Y02E60/10Energy storage using batteries

Abstract

The application discloses a special sampling brush for an oral cavity, which relates to the field of medical equipment, and comprises a preparation area and an operation area, wherein the upper side of the preparation area is provided with a preparation groove, the right side of the preparation groove penetrates through the right side of the preparation area, the operation area is fixedly connected to the right upper part of the preparation area, the left end inside the operation area is provided with a buffer wheel, the buffer wheel is fixedly connected with a plurality of L-shaped contact blocks, a plurality of samplers are inserted into the preparation groove, each sampler comprises a sampling tube and a sampling brush, the sampling brush is arranged in the sampling tube, the openings at the left end and the right end inside the sampling tube are respectively provided with a flange, the right end of the sampling tube is provided with a supporting plate, the left side of the pushing block is fixedly connected with a swab rod, and spiral bristles are arranged on the swab rod. By adopting the technical scheme of the application, the sampling success rate can be improved through the spiral brush hair; the sampling swab can be replaced quickly and the sampled swab can be stored, the validity of a sample can be prolonged, the centralized placement can also achieve the effect of single isolation, and cross infection is avoided.

Description

Special sampling brush in oral cavity
Technical Field
The application relates to the field of medical appliances, in particular to a sampling brush special for an oral cavity.
Background
The method for collecting the oral cavity exfoliated cells for DNA inspection is a non-invasive, painless and noninvasive method, is simple to operate, does not need disinfection, and is used for performing forensic DNA inspection and establishing a DNA database by using the oral cavity exfoliated cells of the forensic people and criminal suspects extracted at home and abroad at present, and in addition, in the conventional medical diagnosis, the oral cavity exfoliated cells can be adopted to analyze gene fragments of the oral cavity exfoliated cells for disease diagnosis, so that a treatment scheme is planned for patients. When sampling, the oral mucosa cells must be sampled by a sampling tool, and the cells are stored in a slide, a specific container or a solution and transferred to a laboratory for inspection and analysis. The existing oral cavity sampling tool is generally a swab, the swab comprises a swab rod and a swab head, the swab head is of a cylindrical structure generally, and cotton wool is filled in the brush head.
The current swabs generally have the following disadvantages: firstly, the surface area of a cylindrical swab head is limited, the number of removed cells is limited when the oral cavity exfoliated cells are collected, the inaccuracy of a detection result is easy to cause, and the application of the subsequent cell extraction and DNA extraction is limited; secondly, oral cavity sampling always sends the detection in unison after can extracting a plurality of body numbers in actual operation in-process, leads to the sample unable timely application, and the long-time detention can not appear fungi, bacterial pollution influence the circumstances of testing result, and the sample is all unified and is placed in a position, also can have cross infection's possibility to destroy the sample, influence the testing result.
Disclosure of Invention
The application aims to provide a sampling brush special for an oral cavity, which can improve the sampling success rate through spiral bristles; the sampling swab can be replaced quickly and the sampled swab can be stored, the validity of a sample can be prolonged, the centralized placement can also achieve the effect of single isolation, and cross infection is avoided.
In order to achieve the above purpose, the present application provides the following technical solutions:
the special sampling brush for the oral cavity comprises a handle and a sampling device, wherein the handle comprises a preparation area and an operation area, the upper side of the preparation area is provided with a preparation groove, the right side of the preparation groove penetrates through the right side of the preparation area, the operation area is fixedly connected to the upper right side of the preparation area, the left side of the preparation groove is provided with a first through groove penetrating through the preparation area, and the left ends of the front side and the rear side of the preparation groove are symmetrically provided with guide grooves;
the left end inside the operation area is provided with a buffer wheel, the buffer wheel is fixedly connected with a plurality of L-shaped contact blocks, the right side of the buffer wheel is provided with a force storage device, the force storage device comprises two rotating columns which are fixedly arranged left and right, the two rotating columns are respectively and rotatably connected with a limiting wheel, the two limiting wheels are connected through a conveying belt, the conveying belt is fixedly connected with a plurality of first limiting blocks, the center of the front side of one limiting wheel is fixedly connected with a concentric gear, the upper side of the concentric gear is meshed with an operation gear, the upper end of the operation gear penetrates through the upper side of the operation area and is arranged outside, the lower side of the conveying belt is provided with an ejection rod, the upper side of the ejection rod is provided with a second limiting block, the second limiting block can be abutted against the first limiting block at a certain moment, the left end of the ejection rod is sleeved with a guide ring, the right end of the ejection rod is fixedly connected with a spring, the free end of the spring is fixedly connected with the inner wall of the operation area, a locking plate is rotatably arranged between the buffer wheel and the force storage device, the middle part of the locking plate is provided with a locking plate, and the right end of the locking plate can be abutted against the first limiting block at a certain moment respectively;
the sampler comprises a sampling tube and a sampling brush, wherein the sampling brush is arranged in the sampling tube, annular flanges are arranged at openings at the left end and the right end of the inside of the sampling tube, guide blocks are arranged on the front side and the rear side of the left end of the outside of the sampling tube, supporting plates are arranged on the upper side and the lower side of the right end of the sampling tube, the sampling brush comprises a pushing block, a swab rod is fixedly connected to the left side of the pushing block, and spiral bristles are arranged on the swab rod.
By adopting the technical scheme, a plurality of samplers can be placed in the preparation groove in advance when the sampling brush is used, a supporting piece on the upper side of the right end of the lowest sampler is lapped on the contact block and is fixed in the middle of the preparation area, the front end of the sampling pipe is aligned with the upper end of the first through groove, then the operation area is held by hands, the operation gear is stirred by the thumb, the operation gear is rotated clockwise, the concentric gear and the limiting wheel are driven to rotate clockwise by the operation gear, the driving belt is driven to move, at the moment, the first limiting block is separated from the second limiting block, the ejection rod ejects leftwards under the action of the spring to push the sampling brush out of the sampling pipe, and at the moment, the left side of the pushing block is propped against the right side of the annular flange;
the spiral brush hair can sample better, improve sampling point and take turns to the success rate, after medical personnel samples, stir the operating gear, the first stopper of second can conflict the second stopper, and along with the motion of conveyer belt, make the ejector pin slide backward, ejector pin compression spring, in this process, the right-hand member of third first stopper contact lock plate, continue to remove and can make the lock plate rotate, the contact block no longer receives the restriction of lock plate, the buffer wheel begins to rotate, current sample ware no longer receives the support of contact block in the rotation process, slide downwards along the guide way, an adjacent sample ware is at the in-process of sliding downwards, the backing sheet is taken on the contact block, sample brush after the sampling breaks the swab pole, and insert from the sampling pipe right-hand member, with quick replacement sampling swab and preserve the swab after the sampling, can prolong sample validity, place in a concentrated also can play single effect of keeping apart, avoid cross infection.
Preferably, a ratchet wheel is arranged at the joint of the rotating column and the limiting wheel, so that the limiting wheel rotates anticlockwise relative to the rotating column.
The ratchet wheel can only rotate anticlockwise to control the ejection rod to move backwards.
Preferably, the front end threaded connection of sampling tube has the protection cap, the joint hole has been seted up at the middle part of protection cap, the joint has the joint piece in the joint hole, the outside of backing sheet also is equipped with the screw thread.
When the sampler is not used, the protective cap covers the left end of the sampler, and protects the brush hair together with the propelling block at the right end, so that the brush hair is prevented from being polluted by other pollutants, after sampling, the sampling brush is inserted from the right end of the sampling tube, then the protective cap is fixed to the rear end of the sampling tube through threads, the whole sampling tube is sealed, cross contamination is avoided, at the moment, the right end of the swab rod pushes the clamping block open and passes through the clamping hole, and the sampling tube is also convenient to take.
Preferably, a first elastic clamping column and a second elastic clamping column which are splayed are arranged in the middle of the swab rod between the pushing block and the brush hair, and folds are arranged on the swab rod between the first elastic clamping column and the second elastic clamping column.
After the sampling brush is pushed out of the sampling tube, the second elastic clamping column is matched with the pushing block, so that the sampling brush is fixed at the left end of the sampling tube, after sampling, the swab rod can be easily broken along a crease, the sampling brush is inserted from the right end of the sampling tube, under the action of the first elastic clamping column, the sampling brush can be clamped at the right end of the sampling tube and then matched with the protective cap, the position of the sampling brush in the sampling tube is fixed, the sampling brush is prevented from shaking in the sampling tube in the moving process, the influence on cells on bristles is caused, and the subsequent detection result is influenced.
Preferably, elastic contact pieces are symmetrically arranged on the front side and the rear side of the lower end of the guide groove.
The elastic contact piece can prevent the sampler from automatically sliding down when falling to the lowest end of the preparation groove, and simultaneously, the sampler is convenient to take out.
Drawings
FIG. 1 is a cross-sectional view of a sampling brush according to an embodiment of the present application;
FIG. 2 is a top view of a sampling brush according to an embodiment of the present application;
FIG. 3 is a cross-sectional view of a sampler according to an embodiment of the present application in a use state;
fig. 4 is a cross-sectional view of a preliminary region along the P direction according to an embodiment of the present application.
Detailed Description
The application is described in further detail below with reference to the attached drawings and embodiments:
reference numerals in the drawings of the specification include: the sampling tube 1, the preparation area 2, the locking plate 3, the concentric gear 4, the operation gear 5, the limit wheel 6, the rotating column 7, the swab rod 8, the brush hair 9, the second elastic clamping column 10, the first elastic clamping column 11, the supporting piece 12, the contact block 13, the buffer wheel 14, the guide ring 15, the ejection rod 16, the first limit block 17, the second limit block 18, the protective cap 19, the guide groove 20, the preparation groove 21, the first through groove 22, the elastic contact piece 23, the guide block 24 and the pushing block 25.
As shown in fig. 1 to 4, a sampling brush specially used for oral cavity comprises a handle and a sampling device, wherein the handle comprises a preparation area 2 and an operation area, the upper side of the preparation area 2 is provided with a preparation groove 21, the right side of the preparation groove 21 penetrates through the right side of the preparation area 2, the operation area is fixedly connected to the upper right side of the preparation area 2, the left side of the preparation groove 21 is provided with a first through groove 22 penetrating through the preparation area 2, the left ends of the front side and the rear side of the preparation groove 21 are symmetrically provided with guide grooves 20, and the front side and the rear side of the lower end of the guide groove 20 are symmetrically provided with elastic contact pieces 23.
The left end inside the operation area is equipped with buffer wheel 14, buffer wheel 14 fixedly connected with a plurality of L type contact blocks 13, the right side of buffer wheel 14 is equipped with holds the power device, hold the power device and include two rotation post 7 of controlling fixed setting, all rotate on two rotation post 7 and be connected with spacing wheel 6, be connected through the conveyer belt between two spacing wheels 6, the junction of rotation post 7 and spacing wheel 6 is equipped with the ratchet, make spacing wheel 6 only can anticlockwise rotation, fixedly connected with a plurality of first stoppers 17 on the conveyer belt, the front side center fixedly connected with concentric gear of one of them limiting wheel 6, the upside meshing of concentric gear has operating gear 5, operating gear 5 upper end runs through the upside of operation area and is arranged in outside, the below of conveyer belt is equipped with ejection rod 16, the upside of ejection rod 16 is equipped with second stopper 18, the second stopper 18 can be inconsistent with first stopper 17 at a moment, the left end cover of ejection rod 16 is equipped with guide ring 15, ejection rod 16 right-hand member fixedly connected with the spring, the free end and the operation area inner wall fixed connection of spring, the front side center fixedly connected with of one of limiting wheel 6, the upper side center gear of concentric gear has, the upper side meshing of operating gear 5, the upper side of operating gear 5 runs through the upside of operating gear 5 outside in the operation area, the below is equipped with ejection rod 16, the upper end 3 is equipped with a torsion spring 13 with between the locking plate 3, the right side locking plate 3, the locking plate 3 can be contacted with each side 13 respectively.
The sampler comprises a sampling tube 1 and a sampling brush, the sampling brush is arranged in the sampling tube 1, annular flanges are arranged at openings at the left end and the right end of the inside of the sampling tube 1, guide blocks 24 are arranged on the front side and the rear side of the left end of the outer side of the sampling tube 1, supporting pieces 12 are arranged on the upper side and the lower side of the right end of the sampling tube 1, the sampling brush comprises a pushing block 25, a swab rod 8 is fixedly connected to the left side of the pushing block 25, spiral bristles 9 are arranged on the swab rod 8, a protective cap 19 is connected to the front end of the sampling tube 1 in a threaded manner, a clamping hole is formed in the middle of the protective cap 19, clamping blocks are clamped in the clamping hole, threads are also arranged on the outer side of the supporting pieces 12, a first elastic clamping column 11 and a second elastic clamping column 10 which are in an eight shape are arranged in the middle of the swab rod 8 between the pushing block 25 and the bristles 9, and folds are arranged on the swab rod 8 between the first elastic clamping column 11 and the second elastic clamping column 10.
The specific implementation process is as follows:
when the sampler is used, a plurality of samplers with the protective caps 19 removed are placed in the preparation groove 21 in advance, the guide blocks 24 of the samplers are embedded in the guide grooves 20, the support piece 12 on the upper side of the right end of the lowermost sampler is lapped on the contact block 13 and fixed in the middle of the preparation area 2, the front end of the sampling tube 1 is aligned with the upper end of the first through groove 22, then the operation area is held by hands, the operation gear 5 is stirred by the thumb, the operation gear 5 rotates clockwise, the operation gear 5 drives the concentric gear and the limiting wheel 6 to rotate anticlockwise, the driving belt is driven to move, at the moment, the first limiting block 17 is separated from the second limiting block 18, the ejection rod 16 ejects leftwards under the action of the spring, the sampling brush is pushed out of the sampling tube 1, at the moment, the left side of the pushing block 25 is abutted against the right side of the annular flange, and the second elastic clamping post 10 is matched with the pushing block 25, so that the sampling brush is fixed at the left end of the sampling tube 1;
the spiral brush hair 9 can sample better, improve the success rate of sampling, medical personnel sample the back, stir operating gear 5, the first stopper 17 of second can conflict second stopper 18, and along with the motion of conveyer belt, make ejection rod 16 backward slip, ejection rod 16 compression spring, in this process, the right-hand member of third first stopper 17 contact lock plate 3, continue to remove and can make lock plate 3 rotate, contact block 13 no longer receives lock plate 3's restriction, buffer wheel 14 begins to rotate, current sampler no longer receives the support of contact block 13 in the rotation process, slide downwards along guide way 20, adjacent one sampler is in the in-process of downwardly sliding, supporting plate 12 is taken on contact block 13, the sample brush after the sampling is along crease light rupture swab pole 8, and insert from sampling tube 1 right-hand member, under the effect of first elasticity card post 11, can be with the sample brush card at the right-hand member of sampling plate 1, the rear end that passes through screw thread fastening to sampling tube 1, whole sampling tube 1, cross contamination block 8 also takes out the sample rod from the top end through the time, can take out the sample from the sample, the effect of sample is concentrated in the time, can be realized by the sample isolation device, the sample is convenient to place in this method, the sample is also from the top-down, the sample is convenient to take out, the sample from the top-up, the top-down is convenient to take the top-to place, and can take out.
The foregoing is merely exemplary of the present application, and specific technical solutions and/or features that are well known in the art have not been described in detail herein. It should be noted that, for those skilled in the art, several variations and modifications can be made without departing from the technical solution of the present application, and these should also be regarded as the protection scope of the present application, which does not affect the effect of the implementation of the present application and the practical applicability of the patent. The protection scope of the present application is subject to the content of the claims, and the description of the specific embodiments and the like in the specification can be used for explaining the content of the claims.

Claims (4)

1. The utility model provides a special sampling brush in oral cavity, includes handle and sampling device, its characterized in that: the handle comprises a preparation area and an operation area, wherein the upper side of the preparation area is provided with a preparation groove, the right side of the preparation groove penetrates through the right side of the preparation area, the operation area is fixedly connected to the upper right side of the preparation area, the left side of the preparation groove is provided with a first through groove penetrating through the preparation area, and the left ends of the front side and the rear side of the preparation groove are symmetrically provided with guide grooves;
the left end inside the operation area is provided with a buffer wheel, the buffer wheel is fixedly connected with a plurality of L-shaped contact blocks, the right side of the buffer wheel is provided with a force storage device, the force storage device comprises two rotating columns which are fixedly arranged left and right, the two rotating columns are respectively and rotatably connected with a limiting wheel, the two limiting wheels are connected through a conveying belt, the conveying belt is fixedly connected with a plurality of first limiting blocks, the center of the front side of one limiting wheel is fixedly connected with a concentric gear, the upper side of the concentric gear is meshed with an operation gear, the upper end of the operation gear penetrates through the upper side of the operation area and is arranged outside, the lower side of the conveying belt is provided with an ejection rod, the upper side of the ejection rod is provided with a second limiting block, the second limiting block can be abutted against the first limiting block at a certain moment, the left end of the ejection rod is sleeved with a guide ring, the right end of the ejection rod is fixedly connected with a spring, the free end of the spring is fixedly connected with the inner wall of the operation area, a locking plate is rotatably arranged between the buffer wheel and the force storage device, the middle part of the locking plate is provided with a locking plate, and the right end of the locking plate can be abutted against the first limiting block at a certain moment respectively;
the sampling device comprises a sampling tube, a sampling brush, a guide block, a supporting piece, a swab rod, a spiral brush and a sampling brush, wherein the sampling tube is inserted into the preparation groove, the sampling brush comprises the sampling tube and the sampling brush, the opening parts at the left end and the right end of the inside of the sampling tube are respectively provided with an annular flange, the front side and the rear side of the left end of the outside of the sampling tube are respectively provided with the guide block, the upper side and the lower side of the right end of the sampling tube are respectively provided with the supporting piece, the sampling brush comprises the propelling block, the swab rod is fixedly connected to the left side of the propelling block, and the swab rod is provided with the spiral brush hair;
the middle part of the swab rod between the pushing block and the brush hair is provided with a first elastic clamping column and a second elastic clamping column which are splayed, and a crease is arranged on the swab rod between the first elastic clamping column and the second elastic clamping column;
when the sampler is used, a plurality of samplers with the protective caps removed are placed in the preparation groove in advance, the guide blocks of the samplers are embedded in the guide grooves, the support piece on the upper side of the right end of the lowermost sampler is lapped on the contact block and is fixed in the middle of the preparation area, the front end of the sampling tube is aligned with the upper end of the first through groove, then the operation area is held by the hand, the operation gear is stirred by the thumb, the operation gear is rotated clockwise, the concentric gear and the limiting wheel are driven to rotate anticlockwise, the driving belt is driven to move, at the moment, the first limiting block is separated from the second limiting block, the ejection rod ejects the sampling brush leftwards under the action of the spring to push the sampling tube, at the moment, the left side of the pushing block is abutted against the right side of the annular flange, and the second elastic clamping column is matched with the pushing block, so that the sampling brush is fixed at the left end of the sampling tube;
the utility model provides a sample can be carried out better to spiral brush hair, improve the success rate of sampling, medical personnel sample back, stir the operating gear, the first stopper of second can conflict the second stopper, and along with the motion of conveyer belt, make the ejector pin slide backward, ejector pin compression spring, in this process, the right-hand member of third first stopper contact locking plate, continue to remove and can make the locking plate rotate, the contact block no longer receives the restriction of locking plate, the buffer wheel begins to rotate, current sampler no longer receives the support of contact block in the rotation process, slide downwards along the guide way, an adjacent sampler is at the in-process of sliding downwards, the backing sheet is taken on the contact block, the sampling brush after the sampling is along the light broken swab pole of crease, and insert from the sampling tube right-hand member, under the effect of first elasticity card post, can with the sampling brush card at the right-hand member of sampling tube, pass through the screw thread fastening to the rear end of sampling tube with the protection cap, seal whole sampling tube, avoid cross contamination.
2. The oral dedicated sampling brush of claim 1, wherein: the ratchet wheel is arranged at the joint of the rotating column and the limiting wheel, so that the limiting wheel rotates anticlockwise relative to the rotating column.
3. The oral dedicated sampling brush of claim 1, wherein: the front end threaded connection of sampling tube has the protection cap, the joint hole has been seted up at the middle part of protection cap, the joint has the joint piece in the joint hole, the outside of backing sheet also is equipped with the screw thread.
4. The oral dedicated sampling brush of claim 1, wherein: elastic contact pieces are symmetrically arranged on the front side and the rear side of the lower end of the guide groove.
CN202111150132.9A 2021-09-29 2021-09-29 Special sampling brush in oral cavity Active CN113876363B (en)

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CN113876363B true CN113876363B (en) 2023-09-08

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