CN110664442A - Nucleic acid detects with collecting storage facilities - Google Patents

Nucleic acid detects with collecting storage facilities Download PDF

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Publication number
CN110664442A
CN110664442A CN201911139591.XA CN201911139591A CN110664442A CN 110664442 A CN110664442 A CN 110664442A CN 201911139591 A CN201911139591 A CN 201911139591A CN 110664442 A CN110664442 A CN 110664442A
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CN
China
Prior art keywords
wall
barrel
cylinder
sliding
block
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Pending
Application number
CN201911139591.XA
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Chinese (zh)
Inventor
虞龙
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Huzhou Dinghai Biological Science And Technology Co Ltd
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Huzhou Dinghai Biological Science And Technology Co Ltd
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Priority to CN201911139591.XA priority Critical patent/CN110664442A/en
Publication of CN110664442A publication Critical patent/CN110664442A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0096Casings for storing test samples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0291Instruments for taking cell samples or for biopsy for uterus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B2010/0216Sampling brushes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention discloses a collection and storage device for nucleic acid detection, which comprises a barrel, wherein the left side of the barrel is in an open design, the left side of the inner wall of the barrel is movably connected with two arc-shaped blocks through a pin shaft, the right sides of the two arc-shaped blocks are provided with first sliding grooves in a machining mode, the left side of a spring is clamped with the right side of a block body, the right side of the spring is clamped with the left side of a through hole block, the outer wall of a round rod penetrates through the right side of the barrel, the right side of the round rod is fixedly connected with a handle, and the handle is attached to the right side of. This nucleic acid detects with collecting storage equipment passes through the cooperation of arc piece, barrel and sample brush for the sample detection result is inaccurate, and this nucleic acid detects with collecting storage equipment passes through the cooperation of third barrel, barrel lid and sample brush, makes the sample brush accomplish the sample and collects the back, and the patient installs the barrel lid to the third barrel on, has avoided having had to store and transport this sample brush after the user's sample, and the operation process is complicated.

Description

Nucleic acid detects with collecting storage facilities
Technical Field
The invention relates to the technical field of medical treatment, in particular to a collection and storage device for nucleic acid detection.
Background
Nucleic acid is a substance which is more important than protein, fat, carbohydrate, vitamin, mineral, water and cellulose for maintaining life, is the core for supporting the whole life activity, is the most basic life source of human, and can not be metabolized without nucleic acid; the method is characterized in that the method can not be used for successive generations without nucleic acid, if a human body lacks nucleic acid, even if the human body eats food containing more protein, the human body can not be converted into protein in the human body, the nucleic acid is the basis of synthetic protein and plays an extremely important role in the processes of growth, development, reproduction and heredity of the human body, when a medical institution inspects gynecological inflammation, cervical cancer and other diseases of female patients, cervical exfoliated cells of the cervix are generally sampled, the sampling work can be carried out in a special treatment room arranged in the medical health institution or a physical examination center with the help of doctors, or the patient to be sampled automatically samples through a self-used sampler, then the sample is sealed and stored to a set medical institution, in the prior art, the used sampler is a sampling brush, the sampling brush is required to be inserted into the vagina of the sampling patient for sampling, and a sample storage device is additionally arranged, so that after the sampling is finished, the patient places the sample on the sample brush and stores and the mail in the device of depositing sealed, exists the patient at this in-process and for taking a sample by oneself, and at the sample in-process, the sample brush can expose in the external world, probably exists because external environment influences, causes the sample on the sample brush to receive the pollution for the unsafe problem of sample test result, and need store and transport this sample brush after having the user's sample, problem that the operation process is complicated.
Disclosure of Invention
The invention aims to provide a collection and storage device for nucleic acid detection, which aims to solve the problems that in the prior art provided by the background art, a used sampler is a sampling brush, a sampling brush needs to be inserted into a vagina by a sampling patient for sampling, a sample storage device needs to be additionally arranged, so that after sampling is finished, the sample on the sampling brush is placed in a sealing device by the patient for storage and mailing, the patient can sample by himself in the process, the sampling brush is exposed outside in the sampling process, the sample on the sampling brush is possibly polluted due to the influence of the external environment, the sampling detection result is inaccurate, and the sampling brush needs to be stored and transported after the user samples, and the operation process is complex.
In order to achieve the purpose, the invention provides the following technical scheme: a collection and storage device for nucleic acid detection comprises a barrel, wherein the left side of the barrel is in an open design, the left side of the inner wall of the barrel is movably connected with two arc-shaped blocks through a pin shaft, first sliding grooves are formed in the right sides of the two arc-shaped blocks, sampling brushes are clamped on the left sides of the two arc-shaped blocks, through hole blocks are sleeved on the inner wall of the barrel, a handle is sleeved on the outer wall of the right side of the barrel, and abutting mechanisms are arranged on the inner walls of the two first sliding grooves;
the abutting mechanism comprises a trapezoidal sliding block, a round rod, a block body, a spring and a handle;
trapezoidal slider slides and links to each other in the inner wall of two first spouts, trapezoidal slider supports tightly to two arc pieces, the right side rigid coupling of trapezoidal slider has the round bar, the space clearance fit that forms between the outer wall of round bar and two arc pieces, the block has been cup jointed to the outer wall of round bar, the outer wall clearance fit of round bar has the inner wall of through-hole piece, the outer wall clearance fit of round bar has the spring, the left side joint of spring has the right side of block, the right side joint of spring has the left side of through-hole piece, the outer wall of round bar runs through in the right side of barrel, the right side rigid coupling of round bar has the handle, the handle is laminated mutually with the right side of barrel.
Preferably, the round rods are distributed at the center of the cylinder.
Preferably, the outer wall of the cylinder body is provided with an adjusting mechanism;
the adjusting mechanism comprises a second cylinder, a second block, a sliding rod, a second spring, a sliding sleeve and a second handle;
second barrel clearance fit is in the outer wall of barrel, the equal rigid coupling in inner wall top and the bottom of second barrel has two second blocks, two the inboard rigid coupling of second block has the slide bar, two the outer wall of slide bar slides and links to each other has the sliding sleeve, two the inboard of sliding sleeve is in the same place with the outer wall rigid coupling of barrel, the outer wall clearance fit of slide bar has the second spring, the left side rigid coupling of second spring is on the right side of left side second block, the right side rigid coupling of second spring is in the left side of sliding sleeve, the second handle has been cup jointed on the outer wall right side of second barrel.
Preferably, the two slide bars are symmetrically distributed about the cylinder axis.
Preferably, the inner wall of the second cylinder body is provided with an auxiliary mechanism;
the auxiliary mechanism comprises a sliding groove block and a second sliding block;
the two sliding groove blocks are fixedly connected to the top and the bottom of the inner wall of the second barrel respectively, the inner wall of each sliding groove block is connected with a second sliding block in a sliding mode, and the inner side of each second sliding block is fixedly connected to the top and the bottom of the outer wall of the barrel.
Preferably, the outer wall of the second cylinder body is provided with a storage mechanism;
the storage mechanism comprises a third cylinder and a cylinder cover;
the third barrel is connected to the outer wall of the second barrel through threads, the left side of the third barrel is open, and the left side of the third barrel is connected with the barrel cover through threads.
Compared with the prior art, the invention has the beneficial effects that: the invention has scientific and reasonable structure and safe and convenient use.
This nucleic acid detects with collecting storage device passes through the cooperation of arc piece, barrel and sample brush for the sample brush can carry out quick dismantlement and installation, makes this nucleic acid detect with collecting storage device accomplish the back through the sample brush sample, and the person of conveniently detecting is dismantled and is carried out the detection to the sample brush.
This nucleic acid detects with collecting storage device passes through the cooperation of barrel, second barrel and third barrel for the sample brush sample is accomplished the back, and the inside of sample brush withdrawal second barrel has been avoided having had the patient for the sample by oneself, and at the sample in-process, the sample brush can expose in the external world, probably has because external environment influences, causes the sample on the sample brush to receive the pollution, makes the sample testing result inaccurate.
This nucleic acid detects with collecting storage facilities passes through the cooperation of third barrel, barrel lid and sample brush for the sample brush accomplishes the sample and collects the back, and the patient is installed the barrel lid to the third barrel on, has avoided having to store and transport this sample brush after the user's sample, and operation process is complicated.
Drawings
FIG. 1 is a schematic diagram of the connection relationship of the present invention;
FIG. 2 is a schematic view of the connection relationship between the sampling brush, the arc block and the pin shaft in FIG. 1;
FIG. 3 is a schematic view showing the connection relationship between the vent block, the second block and the second spring in FIG. 1;
fig. 4 is a schematic view of the connection relationship between the third cylinder, the chute block and the second slider in fig. 1.
In the figure: 1. barrel, 2, arc piece, 3, round pin axle, 4, first spout, 5, sample brush, 6, support tight mechanism, 601, trapezoidal slider, 602, round bar, 603, block, 604, spring, 605, handle, 7, adjustment mechanism, 701, second barrel, 702, second block, 703, slide bar, 704, second spring, 705, sliding sleeve, 706, second handle, 8, complementary unit, 801, spout piece, 802, second slider, 9, storage mechanism, 901, third barrel, 902, barrel lid, 10, opening piece, 11, handle.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention. Referring to fig. 1-4, the present invention provides a technical solution: a collection and storage device for nucleic acid detection comprises a barrel body 1, wherein the left side of the barrel body 1 is in an open design, the left side of the inner wall of the barrel body 1 is movably connected with two arc-shaped blocks 2 through a pin shaft 3, so that the arc-shaped blocks 2 can rotate on the left side of the inner wall of the barrel body 1, first sliding grooves 4 are processed on the right sides of the two arc-shaped blocks 2, the first sliding grooves 4 are inclined grooves, sampling brushes 5 are clamped on the left sides of the two arc-shaped blocks 2, the sampling brushes 5 are used for collecting falling cervical cells in a vagina, through hole blocks 10 are sleeved on the inner wall of the barrel body 1, handles 11 are sleeved on the outer wall of the right side of the barrel body 1, abutting mechanisms 6 are arranged on the inner walls of the two first sliding grooves 4, each abutting mechanism 6 comprises a trapezoidal sliding block 601, a round rod 602, a block 603, a spring 604 and a handle 605, the trapezoidal sliding block 601 is connected with the inner walls of the, the sampling brush 5 is fixed in the opposite direction and taken down, so that the trapezoidal sliding block 601 tightly supports the two arc-shaped blocks 2, the two arc-shaped blocks 2 can fix the sampling brush 5, the right side of the trapezoidal sliding block 601 is fixedly connected with a round rod 602, the round rod 602 is fixed on the right side of the trapezoidal sliding block 601, the outer wall of the round rod 602 is in clearance fit with the gap formed between the two arc-shaped blocks 2, so that the round rod 602 can slide left and right in the gap formed between the two arc-shaped blocks 2, the outer wall of the round rod 602 is sleeved with a block 603, the outer wall of the round rod 602 is in clearance fit with the inner wall of the through hole block 10, so that the round rod 602 can move left and right in the inner wall of the through hole block 10, the outer wall of the round rod 602 is in clearance fit with a spring 604, the elastic coefficient of the spring 604 is 2500-, the outer wall of pole 602 runs through in the right side of barrel 1 for pole 502 can remove about the right side of barrel 2, and the right side rigid coupling of pole 602 has handle 605, and handle 605 is used for driving pole 602 to remove, and then drives trapezoidal slider 601 and remove, and handle 605 laminates mutually with the right side of barrel 1, and pole 602 is located the centre of a circle department of barrel 1 and distributes, makes trapezoidal slider 601 can support tightly two even atress of arc piece 2.
The outer wall of the cylinder 1 is provided with an adjusting mechanism 7, the adjusting mechanism 7 comprises a second cylinder 701, a second block 702, a sliding rod 703, a second spring 704, a sliding sleeve 705 and a second handle 706, the second cylinder 701 is in clearance fit with the outer wall of the cylinder 1, so that the cylinder 1 can move left and right on the inner wall of the second cylinder 701, the top and the bottom of the inner wall of the second cylinder 701 are fixedly connected with the two second blocks 702, the sliding rod 703 is fixedly connected with the inner sides of the two second blocks 702, so that the sliding rod 703 is fixed on the inner sides of the two second blocks 702, the outer walls of the two sliding rods 703 are connected with the sliding sleeve 705 in a sliding manner, so that the sliding sleeve 705 can slide left and right on the outer wall of the sliding rod 703, the inner sides of the two sliding sleeves 705 are fixedly connected with the outer wall of the cylinder 1, so that the handle 11 can drive the cylinder 1 to slide left and right inside the second cylinder 701, the outer wall of the sliding rod 703 is in clearance fit with the, the left side of the second spring 704 is fixedly connected to the right side of the left second block 702, the right side of the second spring 704 is fixedly connected to the left side of the sliding sleeve 705, the second spring 701 gives a rightward force to the sliding sleeve 705, the right side of the outer wall of the second cylinder 701 is sleeved with the second handle 706, and the two sliding rods 703 are symmetrically distributed about the axis of the cylinder 1, so that the sliding rods 703 can drive the cylinder 1 to horizontally move.
The inner wall of the second cylinder 701 is provided with an auxiliary mechanism 8, the auxiliary mechanism 8 comprises a sliding groove block 801 and a second sliding block 802, the two sliding groove blocks 801 are fixedly connected to the top and the bottom of the inner wall of the second cylinder 701 respectively, the two sliding groove blocks 801 are fixed to the top and the bottom of the inner wall of the second cylinder 701, the inner wall of the sliding groove block 801 is connected with the second sliding block 802 in a sliding mode, the second sliding block 802 can slide left and right on the inner wall of the sliding groove block 801, the inner side of the second sliding block 802 is fixedly connected to the top and the bottom of the outer wall of the cylinder 1, and the moving stability of the cylinder 1 in the second cylinder 701 is improved.
The outer wall of the second cylinder 701 is provided with a storage mechanism 9, the storage mechanism 901 comprises a third cylinder 901 and a cylinder cover 902, the third cylinder 901 is connected to the outer wall of the second cylinder 701 through threads, so that the second cylinder 701 can move the second cylinder 701 by rotating the second handle 706, the depth of the sampling brush 5 entering the vagina is further adjusted, the left side of the third cylinder 901 is open, and the left side of the third cylinder 901 is connected with the cylinder cover 902 through threads, so that the third cylinder 901 can be sealed through the cylinder cover 902.
When the collecting and storing device for nucleic acid detection is used, the patient rotates the cylinder cover 902 to separate the cylinder 902 from the third cylinder 901, after separation, the patient rotates the second handle 706 to move the second cylinder 701 left and right in the third cylinder 901, so that the patient rotates according to the depth of the sampling brush 5 entering the vagina, after rotation, the patient places the third cylinder 901 at the vagina, after placement, the patient pushes the handle 11 to make the handle 11 drive the cylinder 1 to move in the second cylinder 701, so that the cylinder 1 drives the sampling brush 5 to enter the vagina to perform sampling, after sampling, the patient cancels the stress on the handle 11, so that the sliding sleeve 705 drives the cylinder 1 to reset through the elastic deformation of the spring 604, so that the cylinder drives the sampling brush 5 to move into the second cylinder 701, after moving in, the patient installs the cylinder cover to the third cylinder 901, the sampling and the storage are completed, after the sampling and the storage are completed, the patient returns the collection and storage equipment for the nucleic acid detection to the doctor, the doctor takes the collection and storage equipment for the nucleic acid detection, the cylinder cover 902 is separated from the third cylinder 901, the handle 605 is pulled, the handle 605 drives the round rod 602 to move, the trapezoidal sliding block 601 is driven to move, the trapezoidal sliding block 601 is enabled to be cancelled to limit the arc-shaped block 2, and the doctor can take the sampling brush 5 down and perform the detection.
In the description of the present invention, it is to be understood that the terms "coaxial", "bottom", "one end", "top", "middle", "other end", "upper", "one side", "top", "inner", "front", "center", "both ends", and the like, indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the referenced device or element must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention.
In the present invention, unless otherwise expressly specified or limited, the terms "mounted," "disposed," "connected," "secured," "screwed" and the like are to be construed broadly, e.g., as meaning fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; the terms may be directly connected or indirectly connected through an intermediate, and may be communication between two elements or interaction relationship between two elements, unless otherwise specifically limited, and the specific meaning of the terms in the present invention will be understood by those skilled in the art according to specific situations.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (6)

1. The utility model provides a nucleic acid detects with collecting storage facilities, includes barrel (1), open design is done in the left side of barrel (1), the inner wall left side of barrel (1) links to each other through round pin axle (3) activity has two arc pieces (2), two the right side processing of arc piece (2) has first spout (4), two the left side clamp of arc piece (1) is got and is had sample brush (5), through-hole piece (10) have been cup jointed to the inner wall of barrel (1), handle (11), its characterized in that have been cup jointed to the right side outer wall of barrel (1): the inner walls of the two first sliding grooves (4) are provided with abutting mechanisms (6);
the abutting mechanism (6) comprises a trapezoidal sliding block (601), a round rod (602), a block body (603), a spring (604) and a handle (605);
the trapezoidal sliding blocks (601) are connected with the inner walls of the two first sliding chutes (4) in a sliding way, the trapezoidal sliding block (601) tightly supports the two arc-shaped blocks (2), a round rod (602) is fixedly connected to the right side of the trapezoidal sliding block (601), the outer wall of the round rod (602) is in clearance fit with a gap formed between the two arc-shaped blocks (2), the outer wall of the round rod (602) is sleeved with a block body (603), the outer wall of the round rod (602) is in clearance fit with the inner wall of the through hole block (10), the outer wall of the round rod (602) is in clearance fit with a spring (604), the left side of the spring (604) is clamped with the right side of the block body (603), the right side of the spring (604) is clamped with the left side of the through hole block (10), the outer wall of the round rod (602) penetrates through the right side of the cylinder body (1), the right side of round bar (602) is fixedly connected with handle (605), handle (605) is laminated with the right side of barrel (1).
2. The nucleic acid detecting collection and storage device according to claim 1, wherein: the round rods (602) are distributed at the circle center of the cylinder body (1).
3. The nucleic acid detecting collection and storage device according to claim 1, wherein: the outer wall of the cylinder body (1) is provided with an adjusting mechanism (7);
the adjusting mechanism (7) comprises a second cylinder (701), a second block body (702), a sliding rod (703), a second spring (704), a sliding sleeve (705) and a second handle (706);
the utility model discloses a barrel, including barrel (1), second barrel (701) clearance fit outer wall, the inner wall top and the bottom of second barrel (701) all the rigid coupling have two second block bodies (702), two the inboard rigid coupling of n of second block body (702) has slide bar (703), two the outer wall slip of slide bar (703) links up sliding sleeve (705), two the inboard of sliding sleeve (705) is in the same place with the outer wall rigid coupling of barrel (1), the outer wall clearance fit of slide bar (703) has second spring (704), the left side rigid coupling of second spring (704) is in the right side of left side second block body (702), the right side rigid coupling of second spring (704) is in the left side of sliding sleeve (705), second handle (706) has been cup jointed on the outer wall right side of second barrel (701).
4. The nucleic acid detecting collection and storage device according to claim 1, wherein: the two sliding rods (703) are axially symmetrically distributed relative to the barrel (1).
5. The nucleic acid detecting collection and storage device according to claim 1, wherein: an auxiliary mechanism (8) is arranged on the inner wall of the second cylinder (701);
the auxiliary mechanism (8) comprises a sliding groove block (801) and a second sliding block (802);
two the inner wall top and the bottom of inner wall rigid coupling in second barrel (701) respectively of spout piece (801), the inner wall of spout piece (801) slides and links to each other has second slider (802), the inboard rigid coupling in the top and the bottom of barrel (1) outer wall of second slider (802).
6. The nucleic acid detecting collection and storage device according to claim 1, wherein: the outer wall of the second cylinder (701) is provided with a storage mechanism (9);
the storage mechanism (901) comprises a third cylinder (901) and a cylinder cover (902);
the third cylinder (901) is connected to the outer wall of the second cylinder (701) in a threaded manner, the left side of the third cylinder (901) is open, and the left side of the third cylinder (901) is connected with a cylinder cover (902) in a threaded manner.
CN201911139591.XA 2019-11-20 2019-11-20 Nucleic acid detects with collecting storage facilities Pending CN110664442A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201911139591.XA CN110664442A (en) 2019-11-20 2019-11-20 Nucleic acid detects with collecting storage facilities

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201911139591.XA CN110664442A (en) 2019-11-20 2019-11-20 Nucleic acid detects with collecting storage facilities

Publications (1)

Publication Number Publication Date
CN110664442A true CN110664442A (en) 2020-01-10

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CN201911139591.XA Pending CN110664442A (en) 2019-11-20 2019-11-20 Nucleic acid detects with collecting storage facilities

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113876363A (en) * 2021-09-29 2022-01-04 四川大学华西第二医院 Special sampling brush for oral cavity

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113876363A (en) * 2021-09-29 2022-01-04 四川大学华西第二医院 Special sampling brush for oral cavity
CN113876363B (en) * 2021-09-29 2023-09-08 四川大学华西第二医院 Special sampling brush in oral cavity

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