CN113842408A - Composition for treating hyperglycemia and preparation method thereof - Google Patents

Composition for treating hyperglycemia and preparation method thereof Download PDF

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CN113842408A
CN113842408A CN202111210604.5A CN202111210604A CN113842408A CN 113842408 A CN113842408 A CN 113842408A CN 202111210604 A CN202111210604 A CN 202111210604A CN 113842408 A CN113842408 A CN 113842408A
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composition
semen
treating hyperglycemia
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邱衍臣
邱莉雅
邱婧铭
商书畅
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Abstract

The invention belongs to the technical field of Chinese herbal medicines, and discloses a composition for treating hyperglycemia and a preparation method thereof. The composition is prepared into final product with optimal compatibility, and has effects of invigorating spleen, regulating stomach function, regulating qi-flowing, and eliminating dampness. Soothing liver, promoting bile flow, dredging meridian passage, clearing away heat, and dispersing pathogen accumulation. Eliminating phlegm and removing dampness. It is suitable for treating diabetes, heart disease, pulmonary tuberculosis, leg edema, and foot edema. The formula function is as follows: fire tonifies kidney water, warms the fire of the gate of life, opens liver depression, meets heart and kidney, guides fire to origin, and enables water vapor to be self-eliminated and qi and blood to be smooth. The preparation method of the composition is simple and convenient, and the obtained finished product has stable dosage form and is convenient to take.

Description

Composition for treating hyperglycemia and preparation method thereof
Technical Field
The invention belongs to the technical field of Chinese herbal medicines, and particularly relates to a composition for treating hyperglycemia and a preparation method thereof.
Background
Hyperglycemia occurs when the blood glucose level exceeds a predetermined level. The blood sugar is increased, the urine sugar is increased, and osmotic diuresis can be triggered, so that the symptom of diuresis is caused; blood sugar is increased, a large amount of water is lost, the blood osmotic pressure is correspondingly increased, and the hyperthrome can stimulate the thirst center of the hypothalamus, so that the symptoms of thirst and polydipsia are caused; due to the relative or absolute deficiency of insulin, glucose in the body cannot be utilized, and protein and fat consumption is increased, so that weakness and weight loss are caused; to compensate for lost sugar, maintain body movement, require more food intake; this forms the typical "more than three or less" symptom. The symptoms of polydipsia and polyuria of the diabetic patients are in direct proportion to the severity of the disease conditions.
The basic pathology is liver-kidney yin deficiency and dryness-heat tendrilitis, so the two diseases can be cured by treating the disease root without complicated back and forth conditioning.
Disclosure of Invention
In order to solve the above problems of the prior art, the present invention aims to provide a composition for treating hyperglycemia and a preparation method thereof.
The technical scheme adopted by the invention is as follows: the composition for treating hyperglycemia is mainly prepared from the following raw materials in parts by mass:
50-110 parts of semen momordicae, 25-55 parts of semen pharbitidis, 25-55 parts of semen brassicae and 0.1-0.5 part of white pepper.
Semen Momordicae is dry mature seed of Momordicae cochinchinensis (Lour.) Spreng. Harvesting mature fruits in winter, splitting open, sun-drying to half dry, removing pulp, taking out seeds, and drying. Nature and taste: bitter, slightly sweet and cool; is toxic. Meridian tropism: it enters liver, spleen and stomach meridians. The functional indications are as follows: dissipate nodulation and resolve swelling, counteract toxic pathogen and cure sore. Can be used for treating pyocutaneous disease, pyogenic infection, acute mastitis, scrofula, anal fistula, tinea, and tinea. Contains momordic acid, gypsogenin, oleanolic acid, alpha-eleostearic acid, amino acids, and sterol.
Pharbitidis, a common Chinese herbal medicine, is mainly used for purging water, relaxing bowels, and dissolving phlegm and clearing away the retained fluid. The clown is mostly born in mountain irrigation clusters, at the sides of villages and at the sides of roads; and (5) cultivating in multiple ways. Is distributed all over China. Its main functions are purging water, relaxing bowels, resolving phlegm, killing parasites and removing stasis. Can be used for treating edema, constipation, phlegm accumulation, asthma, cough, abdominal pain, ascariasis, and taeniasis. Nature and taste: cold in nature, bitter in taste; is toxic. The components: fatty oils, organic acids, and the like. The stir-baked product has reduced toxicity, mild drug property, no damage to healthy qi, good effect of clearing phlegm and removing food retention, and good smell and good effect of invigorating spleen. Can be used for treating cough and asthma due to excessive phlegm, and food stagnation. Meanwhile, the shell is broken, the texture is crisp, the enzyme is damaged, the effective components are easy to crush and decoct, and the glycoside components can be stored (the glycoside is protected by enzyme). Meridian tropism means lung meridian, kidney meridian and large intestine meridian.
Black pharbitis seed, dry ripe seed, chemical composition: the semen Pharbitidis contains pharbitidis glycoside, pharbitidis acid A and gallic acid. The pharbitis seed glycoside is a mixture of glycosides of various organic acid esters of hydroxy fatty acids, and the pharbitis seed acid obtained by saponification is a mixture containing at least 4 compounds, 2 of which have been purified, and can be hydrolyzed by acid to obtain pharbitis seed acid B, glucose and rhamnose. Contains ergosterol, ergotoxine, pennyroyal, isopennyroyal and hordenine. The seed which is not grown into hot contains gibberellin A20, gibberellin A3 and gibberellin A5. The pharmacological action is as follows: the chemical properties of morning glory seed glycoside are similar to those of bryonine, and the morning glory seed glycoside has strong purgative effect. Morning glory seed glycosides decompose morning glory seed essence when encountering bile and intestinal juice in the intestines, stimulate the intestinal tract, promote peristalsis and cause diarrhea. According to animal experiments, the cathartic effect of the pharbitis seed is not different from that of the pharbitis seed. The principle of the purgative action of pharbitis seed is rarely studied, and unlike magnesium sulfate and rhubarb, the morning glory seed does not cause drastic change of blood sugar level in purgation, but accelerates excretion of inulin in the kidney, and may have diuretic effect. The water and alcohol extract of semen Pharbitidis has purgative effect on mice, but can be decocted to lose effect. The aqueous solution after removing the pharbitidis glycoside still has purgative effect, so besides the known pharbitidis glycoside, it may also contain other purgative components. In vitro tests, the black pharbitis seed and white pharbitis seed have certain anthelmintic effect on ascaris suum. Pharbitidis glycoside can excite isolated rabbit intestine and isolated rat uterus similarly; intravenous injection of 1 mg/kg has no obvious influence on blood pressure and respiration of anesthetized dogs and rabbits. Half of the lethal dose given by subcutaneous injection to mice was 37.5 mg/kg. It is toxic to human body, but not so toxic, and may stimulate the kidney to cause hematuria, and serious cases may damage the nervous system, cause language disorder, coma, etc. besides vomiting, abdominal pain, diarrhea and mucous bloody stool caused by direct stimulation to the stomach and intestine.
White mustard seed, the name of traditional Chinese medicine. Is seed of Brassicaceae plant Sinapis alba L. Has effects of warming lung, eliminating phlegm, activating qi-flowing, resolving hard mass and relieving swelling. It is mainly used for treating cold phlegm cough and asthma, fluid retention, dorsal furuncle, multiple abscess, numbness of limbs, and arthralgia. Pungent taste and warm nature; it enters lung and stomach meridians. Chemical components: the seeds contain glucosinolates and are filled with sinapioside. It also contains fatty oil, myrosinase, sinapine and lysine, arginine, histidine, etc. Also contains 4-hydroxybenzoyl choline and 4-hydroxybenzyl methylamine. The pharmacological action is as follows: 1. respiratory system effects: a small dose can cause reflex tracheal secretion to increase, and has the effects of nausea and phlegm elimination. 2. Effect on skin mucosa: the Sinapis Albae oil obtained by hydrolyzing sinapioside has strong irritation, and can be used for treating skin hyperemia and foaming. 3. Effects on the digestive system: the semen Sinapis Albae powder has effects of promoting salivary secretion, increasing amylase activity, stimulating gastric mucosa in small amount, increasing secretion of gastric juice and pancreatic juice, and promoting vomiting in large amount. 4. Role of pathogenic microorganisms: the water infusion has effect in inhibiting dermatophytes.
White pepper is a dried nearly ripe fruit of pepper of the family Piperaceae. The spice has fragrant smell and is one of the favorite condiments. Pungent and warm. Warming the middle-jiao to dispel cold, descending qi, and eliminating phlegm; mainly produced in Guangdong, Guangxi and Yunnan provinces, the surface is yellowish-white or pale yellowish-white, smooth, and a plurality of light-colored linear stripes are arranged between the top and the base. The medicinal value of the black pepper is slightly higher than that of the black pepper. Pungent and warm. Warm middle energizer and dispel cold, descend qi, resolve phlegm. 1. The main component of pepper is piperine, and also contains a certain amount of aromatic oil, crude protein, starch and soluble nitrogen, so that the pepper has the effects of removing fishy smell, removing greasiness and helping digestion, and the aromatic smell of the pepper can make people have a wide appetite and stimulate appetite; 2. the pepper is warm in nature, is good at warming middle energizer and dispelling cold, has good relieving effect on stomach and abdomen psychroalgia and borborygmus diarrhea caused by stomach cold, and can promote sweating and treat wind-cold type common cold; 3. the dishes with pepper are not easy to deteriorate, which shows that pepper has the functions of antisepsis and bacteriostasis, and can relieve the botulism of fish and shrimp.
Preferably, the composition is mainly prepared from the following raw materials in parts by mass:
70-90 parts of semen momordicae, 35-45 parts of semen pharbitidis, 35-45 parts of semen brassicae and 0.2-0.4 part of white pepper.
Preferably, the composition is mainly prepared from the following raw materials in parts by mass:
80 parts of semen momordicae, 40 parts of semen pharbitidis, 40 parts of semen brassicae and 0.35 part of white pepper.
A method of preparing a composition for treating hyperglycemia, the method comprising the steps of: selecting semen Momordicae, semen Pharbitidis, semen Sinapis Albae and fructus Piperis according to corresponding proportion, mixing, pulverizing, adding solvent, mixing, and gelatinizing to obtain the final product.
Preferably, the semen momordicae, the semen pharbitidis, the semen brassicae and the white pepper are selected according to the corresponding proportion, mixed, crushed and sieved by a sieve of 80-120 meshes.
Preferably, the solvent is prepared by mixing 200-600 parts of water, 10-30 parts of alum, 5-25 parts of sodium sulfite and 30-60 parts of glycerol.
Preferably, the solvent is prepared by mixing 400 parts of water, 15-25 parts of alum, 10-20 parts of sodium sulfite and 45-55 parts of glycerol.
Preferably, the solvent is prepared by mixing 450 parts of water, 20 parts of alum, 15 parts of sodium sulfite and 50 parts of glycerol.
Alum is crystal extracted from alunite as mineral. The main chemical component is aluminum potassium sulfate dodecahydrate. Mineral Chinese medicine, can detoxify and kill parasites, eliminate dampness and relieve itching by external use; internal use can stop bleeding, check diarrhea and resolve phlegm. The main treatment is as follows: stroke; epilepsy; pharyngitis; scabies, tinea and eczema; abscess, deep-rooted carbuncle and abscessPoisoning; scald by hot water or fire; sores in the mouth and tongue; rotten wind eyes; purulent ear; polyps in the nose; sore and hemorrhoid pain; (ii) metrorrhagia and metrostaxis; bleeding; bleeding from injury; chronic diarrhea and dysentery; itching vaginal discharge; rectocele; uterine prolapse, and the like. Alum is sour and astringent in taste, cold, slightly toxic and edible in small amount. So it has antibacterial and astringent effects, and can be used as Chinese medicine. The Alumen is ground into soaking solution, and soaked in foot bath at a ratio of 1:9 for 2 times per week to treat tinea pedis. The alum is burned by fire, crushed into foam and smeared at armpit to remove the odor of the fox. Nature and taste: sourness and astringent taste; cold; is toxic. Meridian tropism: a lung; a spleen; liver; the large intestine; the bladder channel. Mineral Chinese medicine. It can detoxify and kill parasites, dry dampness and relieve itching for external use, stop bleeding for internal use, check diarrhea and resolve phlegm. The main treatment is as follows: stroke. Epilepsy, pharyngitis, scabies, tinea, eczema, carbuncle, toxic swelling, water and fire scald, aphtha, festering stringy wind, purulent pus in purulent otitis media, polyp in nose, sore, hemorrhoid pain, metrorrhagia, epistaxis, traumatic hemorrhage, chronic diarrhea, dysentery, leukorrhagia, pruritus vulvae, rectocele, metroptosis, etc. Alumen is sour and astringent in taste, cold and toxic. So it has antibacterial and astringent effects, and can be used as Chinese medicine. Alum can also be used for preparing aluminum salt, baking powder, paint, tanning material, clarifier, mordant, paper making, waterproof agent, etc. Chemical components: the alunite is alkaline potassium aluminum sulfate [ KAl3(SO4)2(OH)6]Wherein potassium oxide (K)2O) 11.4%, alumina (Al)2O3) 37.0% of sulfur trioxide (SO)3) 38.6%, water (H)2O)13. O%. Alumen is hydrated potassium aluminum sulfate [ KAl (SO)4)2·12H2O]. The pharmacological action is as follows: 1. the antibacterial effect is as follows: has inhibitory effect on Staphylococcus aureus and Proteus vulgaris (test tube method). The compound preparation has obvious inhibition effect (paper disc and plate method) on escherichia coli, pseudomonas aeruginosa, bacillus anthracis, shigella dysenteriae, typhoid bacillus, paratyphoid bacillus, proteus bacillus, staphylococcus, candida albicans and the like, and has the strongest effect on green streptococcus, hemolytic streptococcus, pneumococcus and diphtheria bacillus; has secondary effect on Brucella bovis, Bordetella pertussis and meningococcus, and has no effect on influenza bacillus (paper sheet method). The high-concentration alum solution also has inhibitory effect on human type (H37RV) and bovine type tubercle bacillus. 2. The anti-trichomonas vaginalis effect is as follows: 10% alum solution inThe ratio of the culture solution to the liquid medicine is 1:1 in the test tube, and the trichomonas vaginalis can be obviously resisted. 3. Action of coagulation proteins: alum has strong protein coagulation effect, and can be immediately combined into insoluble substance to precipitate after several drops of alum water are dropped into serum, and has astringent, anti-inflammatory and antiseptic effects at low concentration, and tissue ulceration caused by high concentration. 4. The function of gallbladder promotion: when 0.6g of alum is administrated in duodenum, the bile flow of anesthetized rats is obviously increased. 5. Local stimulation: the local irritation is very large, 0.3-0.5ml of 15% solution is locally injected to make the rabbit have mania, local red swelling and ulceration, and 0.3ml of intravenous injection makes the rabbit have chill and tremble, respiration urgency and purple peripheral blood vessel and show oxygen deficiency. 6. Other functions are as follows: alum has astringent effect and great irritation in oral administration, so it is generally used externally except for lead colic, and can check sweating and harden skin (especially foot); it can also be used for leukorrhagia and ulcer (concentration is 1-5%). Albumin binders are required for binding membranes. In addition, it can be used for stopping bleeding by placing alum stick or powder directly on bleeding point, such as nasal hemorrhage by placing alum solution saturated with cotton ball into nostril.
Sodium sulfite of the formula Na2SO3Common sulfites, white, monoclinic crystals or powders. It has irritation to eyes, skin, and mucosa, and can pollute water source. Toxic sulfide fume is generated by high-temperature decomposition. The industrial production is mainly used for preparing cellulose sulfite, sodium thiosulfate, organic chemicals, bleaching fabrics and the like, and is also used as a reducing agent, a preservative, a dechlorinating agent and the like.
Glycerol, a colorless, sweet, clear, viscous liquid. No bad smell. Has warm and sweet taste. Commonly known as glycerin, absorbs moisture from the air, and also absorbs hydrogen sulfide, hydrogen cyanide and sulfur dioxide. Insoluble in benzene, chloroform, carbon tetrachloride, carbon disulfide, petroleum ether and oils. Relative density 1.26362. Melting point 17.8 ℃. Boiling point 290.0 deg.c (decomposition). Refractive index 1.4746. Flash point (open cup) 176 ℃. Acute toxicity: LD50: 31500mg/kg (per rat). Glycerol is a backbone component of the triglyceride molecule. When the human body takes in the edible fat, the triglyceride in the edible fat passes through the bodyMetabolically break down to form glycerol and store it in adipocytes. Thus, the end products of triglyceride metabolism are glycerol and fatty acids. Can be used as solvent, lubricant, medicament and sweetener.
Preferably, the mass ratio of the total mass of the mixture of the semen momordicae, the semen pharbitidis, the semen brassicae and the white pepper to the solvent is 1:1.5-2.2 wt%.
Preferably, the finished product is a paste formulation.
The invention has the beneficial effects that:
the invention provides a composition for treating hyperglycemia, which is a finished product obtained by optimal compatibility and has the functions of strengthening spleen and stomach, regulating qi and eliminating dampness. Soothing liver, promoting bile flow, dredging meridian passage, clearing away heat, and dispersing pathogen accumulation. Eliminating phlegm and removing dampness. It is suitable for treating diabetes, heart disease, pulmonary tuberculosis, leg edema, and foot edema. The composition is more effective in combination with meridian and acupoint.
The formula function is as follows: fire tonifies kidney water, warms the fire of the gate of life, opens liver depression, meets heart and kidney, guides fire to origin, and enables water vapor to be self-eliminated and qi and blood to be smooth.
The preparation method of the composition is simple and convenient, and the obtained finished product has stable dosage form and is convenient to take.
Detailed Description
The present invention is further illustrated below with reference to specific examples. It will be appreciated by those skilled in the art that the following examples, which are set forth to illustrate the present invention, are intended to be part of the present invention, but not to be construed as limiting the scope of the present invention. The reagents used are all conventional products which are commercially available.
Example 1:
a method of preparing a composition for treating hyperglycemia, the method comprising the steps of: selecting 50 g of semen momordicae, 25 g of semen pharbitidis, 25 g of semen brassicae and 0.1 g of white pepper according to corresponding proportion, mixing, crushing, adding 187.65 g of solvent (water, alum, sodium sulfite and glycerol), mixing uniformly and pasting to obtain the finished paste.
Example 2:
a method of preparing a composition for treating hyperglycemia, the method comprising the steps of: according to the corresponding proportion, 110 g of semen momordicae, 55 g of white ugreek, 55 g of black ugreek, 55 g of white mustard seed and 0.5 g of white pepper are selected, mixed, crushed, added with 606.1 g of solvent (water, alum, sodium sulfite and glycerol), mixed evenly and pasted to obtain the finished product paste.
Example 3:
a method of preparing a composition for treating hyperglycemia, the method comprising the steps of: according to the corresponding proportion, 70 g of semen momordicae, 35 g of white pharbitis seed, 35 g of black pharbitis seed, 35 g of white mustard seed and 0.2 g of white pepper are selected to be mixed, crushed, 385.44 g of solvent (water, alum, sodium sulfite and glycerol) is added, and the mixture is evenly mixed and gelatinized to obtain the finished product paste.
Example 4:
a method of preparing a composition for treating hyperglycemia, the method comprising the steps of: according to the corresponding proportion, 90 g of semen momordicae, 45 g of white pharbitis seed, 45 g of black pharbitis seed, 45 g of white mustard seed and 0.4 g of white pepper are selected to be mixed, crushed, 495.88 g of solvent (water, alum, sodium sulfite and glycerol) is added, and the mixture is evenly mixed and gelatinized to obtain the finished product paste.
Example 5:
a method of preparing a composition for treating hyperglycemia, the method comprising the steps of: according to the corresponding proportion, 80 g of semen momordicae, 40 g of white pharbitis seed, 40 g of black pharbitis seed, 40 g of white mustard seed and 0.35 g of white pepper are selected, mixed, crushed, 440.77 g of solvent (water, alum, sodium sulfite and glycerol) is added, and the mixture is evenly mixed and gelatinized to obtain the finished product paste.
In the practical application process, a mode of combining foot acupuncture is suggested. The foot acupuncture points of acupuncture, twenty-five acupuncture points of the five meridians: 1. liver meridian of foot jueyin: taichong and middle sealing; 2. gallbladder meridian of foot shaoyang: dangling bell, pimple, foot Linqi, ground Wuhui, Xian xi, foot Qiaoyin; 3. spleen meridian of foot taiyin: grand, Shangqiu, Sanyinjiao, Taibai and Dadu; 4. kidney meridian of foot shaoyin: yongquan, Rangu, Taixi, Dazhong, fountain, sea-caring, retentions, and Convergence; 5. stomach meridian of foot yangming: relieving the creek and purging yang; the zang-jiao and the valley.
Administration: the treatment is not only the action of the medicine, but also the combination action of the medicine and the meridian points.
Firstly, preparation before medication: fasting blood glucose was measured once in the morning of the day of administration and recorded as a comparison of therapeutic effect. Preparing 1 piece of bandage, one pair of scissors, one pair of disposable gloves and one pair of brushes. Before administration, the patient should be protected from urination for 15 hours. If the patient must relieve the bowels in the interim, the device can be prepared, as far as possible under the bed.
Secondly, the medicinal paste is applied to 2/3 parts of the bandage by a brush. Applying the medicated end of the bandage to YONGQUAN acupoint, pressing tightly, winding to foot surface until reaching foot neck (three fingers in three yin-deficiency), and cutting and fastening the medicated end of the bandage. Lying on a bed to sleep and not getting out of the bed as far as possible within 15 hours. And the user can walk as little or no as possible. Can walk with the heel without the sole when walking! Otherwise, drug extrusion can seriously affect the therapeutic effect. The next day, the medicine is taken for 15 hours, then the medicine can be removed, and the fasting blood sugar is detected. The blood sugar can reach the standard or basically reach the standard, and the treatment can be finished when the blood sugar is treated once again at night.
Thirdly, consolidation: for preventing recurrence or recurrence, the treatment is carried out once per month within 6 months after treatment, and six times of consolidation treatment are carried out.
Fourthly, contraindication: during the treatment and consolidation period, the pear is not eaten and the sexual intercourse is forbidden.
Fifthly, curative effect: the standard can be reached after one time under normal conditions, and the standard can be stabilized at a normal level for 2-3 months. However, the standard is not equal to the cure, the actual cure needs to be realized, the continuous treatment and medication are needed twice, and the cure requirement can be met by consolidating the six-month prescription.
Clinical cases:
patient 1: sex: male, age: 73, new countryside.
The disease symptoms are as follows: the diabetes mellitus is about 4 years old, the blood sugar of the existing hypoglycemic drug cannot be reduced, the fasting blood sugar is still 141mmml in today's examination, the tongue is dry and astringent, the night urine is too much, and other symptoms do not exist.
Treatment of the condition: visit in the afternoon 7/15/2020. The medical ointment prepared in example 5 was used for foot application therapy. Day 17, 7/2020, with 11 patient daughter WeChat 10 am: the foot therapy is applied 5 o ' clock later and more foot therapy is applied 5 o ' clock later without taking any hypoglycemic drug yesterday, the drug is removed 9 o ' clock earlier today, and then the blood sugar is measured to be 77 mmml. The blood sugar-reducing medicine is obviously effective after being taken again, and the fasting blood sugar is 61 mmml.
Patient 2: sex: male, age: and 62, retirement employees in post urban areas of the parking horse store.
The disease symptoms are as follows: in 2021, 16 months and 4 days, the patients are diagnosed with swollen feet and legs, spontaneous sweating and hyperhidrosis, and the color of the right foot is purple and swollen, which is considered to be diabetic foot according to symptoms. The patient does not trust to look up the blood glucose. The hospital checks that the fasting blood sugar and the blood sugar are 90 mmml.
Treatment of the condition: the ointment prepared in example 5 was applied to the feet for treatment at 24/4/2021. The ointment is applied to feet for 15 hours, and after taking off the medicine in the morning, the fasting blood sugar is 60mmml, and the foot swelling also disappears normally.
Patient 3: sex: female, the principal of retirement pharmacies of the first people's hospitals in the dwelling store city.
The disease symptoms are as follows: checking fasting blood glucose 66mmml at 26 days 6 months 2021; uric acid 462, high blood sugar and uric acid, require treatment.
Treatment of the condition: the ointment prepared in example 5 was applied to the feet at 28 months 6 and 28 days 2021. Early examination of fasting glucose of 61mmml is reported in 2021, 7/month 2; uric acid 337. is normal. Continuously taking eight-ingredient rehmannia pills for consolidation treatment. East wind report on 20 morning on 7 months 20 years 2021: early morning examination of fasting blood glucose of 59 mmml; uric acid 330 was all normal. Report on 9/3/2021: the fasting blood sugar is 59mmml, the uric acid is 330, and the blood sugar and uric acid are stable.
The present invention is not limited to the above alternative embodiments, and any other products in various forms can be obtained by the present invention, and the present invention is within the protection scope of the present invention. The above embodiments should not be construed as limiting the scope of the present invention, and it will be understood by those skilled in the art that modifications may be made to the technical solutions described in the above embodiments, or equivalent substitutions may be made to some or all of the technical features thereof, without departing from the scope of the present invention, and at the same time, such modifications or substitutions may not make the essence of the corresponding technical solutions depart from the scope of the embodiments of the present invention.

Claims (10)

1. The composition for treating hyperglycemia is characterized by being prepared from the following raw materials in parts by mass:
50-110 parts of semen momordicae, 25-55 parts of semen pharbitidis, 25-55 parts of semen brassicae and 0.1-0.5 part of white pepper.
2. The composition for treating hyperglycemia according to claim 1, wherein the composition is prepared from the following raw materials in parts by mass:
70-90 parts of semen momordicae, 35-45 parts of semen pharbitidis, 35-45 parts of semen brassicae and 0.2-0.4 part of white pepper.
3. The composition for treating hyperglycemia according to claim 2, wherein the composition is prepared from the following raw materials in parts by mass:
80 parts of semen momordicae, 40 parts of semen pharbitidis, 40 parts of semen brassicae and 0.35 part of white pepper.
4. A method for preparing a composition for treating hyperglycemia according to any one of claims 1 to 3, comprising the steps of: selecting semen Momordicae, semen Pharbitidis, semen Sinapis Albae and fructus Piperis according to corresponding proportion, mixing, pulverizing, adding solvent, mixing, and gelatinizing to obtain the final product.
5. The method of claim 4, wherein the semen Momordicae, semen Pharbitidis, semen Sinapis Albae, and fructus Piperis are mixed and ground into 80-120 mesh.
6. The method for preparing the composition for treating hyperglycemia according to claim 4, wherein the solvent is prepared by mixing 200-600 parts of water, 10-30 parts of alum, 5-25 parts of sodium sulfite and 30-60 parts of glycerol.
7. The method for preparing a composition for treating hyperglycemia according to claim 6, wherein the solvent is prepared by mixing 400-500 parts of water, 15-25 parts of alum, 10-20 parts of sodium sulfite and 45-55 parts of glycerol.
8. The method for preparing a composition for treating hyperglycemia according to claim 7, wherein the solvent is a mixture of water 450 parts, alum 20 parts, sodium sulfite 15 parts, and glycerin 50 parts.
9. The method for preparing a composition for treating hyperglycemia according to claim 8, wherein the mass ratio of the total mass of the mixture of the semen momordicae, the semen pharbitidis, the semen brassicae and the white pepper to the solvent is 1:1.5-2.2 wt%.
10. The method for preparing a composition for treating hyperglycemia according to claim 4, wherein the final product is a paste preparation.
CN202111210604.5A 2021-10-18 2021-10-18 Composition for treating hyperglycemia and preparation method thereof Pending CN113842408A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102406711A (en) * 2011-12-02 2012-04-11 刘德忠 Medicament for treating diabetes
CN107661394A (en) * 2017-11-20 2018-02-06 刘燕云 A kind of medicine for treating diabetes and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102406711A (en) * 2011-12-02 2012-04-11 刘德忠 Medicament for treating diabetes
CN107661394A (en) * 2017-11-20 2018-02-06 刘燕云 A kind of medicine for treating diabetes and preparation method thereof

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Application publication date: 20211228