CN113230293B - Traditional Chinese medicine composition for dispelling wind and removing toxicity and preparation method thereof - Google Patents

Abstract

The invention relates to the technical field of traditional Chinese medicines, and provides a traditional Chinese medicine composition for dispelling wind and removing toxicity, which comprises the following raw materials: groundsel, paniculate swallowwort root, Chinese gall and common andrographis herb, wherein the mass ratio of the four components is (5-7): (3-5): (2-4): (1-3). Through the technical scheme, the problems that the medicine in the prior art has side effects on the treatment of skin diseases and has high recurrence rate are solved.

Description

Traditional Chinese medicine composition for eliminating wind and removing toxicity and preparation method thereof

Technical Field

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for dispelling wind and removing toxin and a preparation method thereof.

Background

Skin disorders are a general term for disorders occurring in the skin and skin appendages. The skin is used as the first physiological defense line and the largest organ of the human body, constantly participates in the functional activities of the body, maintains the unity and opposition of the body and the natural environment, and the abnormal condition of the body can be reflected on the surface of the skin. Skin diseases not only affect physical health, but also cause panic and social discrimination and even cause psychological diseases of patients. At present, the medicines for treating skin diseases on the market are more, and the externally applied medicines are mostly used. If the external medicine is not selected or used properly, the effect is often ineffective, even the disease condition is aggravated, for example, the dexamethasone ointment has high recurrence rate, and long-term application can also cause a plurality of side effects, can cause cushing's syndrome, immunosuppression secondary infection, and can also cause osteoporosis, femoral head necrosis and other relatively serious complications.

Disclosure of Invention

The invention provides a traditional Chinese medicine composition for dispersing pathogenic wind and removing toxicity and a preparation method thereof, and solves the problems that the medicines in the prior art have side effects on the treatment of skin diseases and have high recurrence rate.

The technical scheme of the invention is as follows:

a traditional Chinese medicine composition for dispelling wind and removing toxicity comprises the following raw materials: groundsel, paniculate swallowwort root, Chinese gall and common andrographis herb, wherein the mass ratio of the four components is (5-7): (3-5): (2-4): (1-3).

As a further technical scheme, the raw materials comprise the following components: the traditional Chinese medicine composition comprises groundsel, paniculate swallowwort root, gallnut and common andrographis herb, wherein the mass ratio of the four components is 6:4:3: 2.

The invention also provides a preparation method of the traditional Chinese medicine composition for dispelling wind and removing toxin, which comprises the following steps:

s1, selecting high-quality raw materials according to the formula requirements and weighing for later use;

s2, putting the raw materials into alcohol, sealing and soaking for 50 days, and shaking the container once a day;

s3, filtering the soaked liquid medicine to obtain an extracting solution for later use;

s4, pouring the glycerol into the extracting solution, and shaking to mix the glycerol and the extracting solution fully and uniformly;

and S5, measuring and packaging.

The invention has the beneficial effects that:

1. the traditional Chinese medicine composition for dispelling wind and removing toxicity disclosed by the invention is a pure traditional Chinese medicine tincture external application medicine, has no toxic or side effect, and is safe and reliable. Is suitable for relieving and treating allergic dermatoses such as urticaria, eczema, dermatitis, and pruritus caused by pathogenic wind and damp toxin invasion, and infectious dermatoses such as folliculitis caused by fire toxin stagnation. The traditional Chinese medicine components and the composition thereof selected by the invention have the effects of clearing heat, detoxifying, calming endogenous wind, relieving itching, reducing swelling and dissipating stagnation, and achieve the expected purpose by actual application.

2. The Chinese medicinal composition for eliminating wind and removing toxicity has monarch, minister, assistant and guide compatibility and main treatment function. Qianlieguang is a monarch drug with bitter, pungent and cold properties. It enters lung and liver meridians. Has the main functions of clearing heat and toxin, killing parasites and relieving itching, dispelling wind and eliminating dampness, and has obvious treatment effect on skin symptoms such as urticaria, eczema, scabies, allergic dermatitis and the like caused by wind evil and damp toxin invasion. Groundsel has a quite strong antibacterial effect on skin symptoms caused by staphylococcus aureus invasion. The paniculate swallowwort root is a ministerial drug, has pungent taste and warm nature. It enters liver and stomach meridians. Has the main functions of dispelling wind and eliminating dampness, relieving pain and itching, inducing diuresis and reducing edema, and activating blood and removing toxicity. Has synergistic effect on monarch drugs, and radix Cynanchi Paniculati has effect in relieving and treating pruritus caused by urticaria and allergic dermatitis. Galla chinensis and Andrographis paniculata are adjuvant drugs, and their properties and tastes are similar. The external traditional Chinese medicine has the main treatment functions, is characterized by clearing heat and detoxicating, cooling blood and relieving swelling, astringing dampness and healing sores, has stronger efficacy of assisting monarch and minister drugs, and has the treatment effect on infectious skin diseases such as folliculitis caused by fire toxin internal depression. Glycerol is a moistening and moistening agent, and can be called half of an adjuvant and a conductant drug. The proper amount of the medicinal liquid can inhibit dryness and keep moisture, restrict the drying speed of alcohol when in use, keep the action time of the medicinal properties on skin and promote the absorption of the medicinal effects.

Drawings

The present invention will be described in further detail with reference to the accompanying drawings and specific embodiments.

FIG. 1 is a dermoscopic image of case 1 before and after treatment;

figure 2 is a dermoscopic picture of case 2 before and after treatment;

figure 3 is a dermoscopic picture of case 3 before and after treatment;

figure 4 is a dermoscopic picture of case 4 before and after treatment;

FIG. 5 is a dermoscopic image of case 5 before and after treatment;

figure 6 is a dermoscopic image of case 6 before and after treatment.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any inventive step, are intended to be within the scope of the present invention.

Example 1

The formula is as follows: 140 g of groundsel, 100 g of paniculate swallowwort root, 80 g of Chinese gall and 60 g of common andrographis herb.

S1, selecting high-quality raw materials according to the formula requirements and weighing for later use;

s2, putting the raw materials into 2500mL of alcohol with the purity of 75%, sealing and soaking for 50 days, and shaking the container once a day;

s3, filtering the soaked liquid medicine with double-layer gauze to obtain an extracting solution for later use;

s4, pouring 150mL of medical glycerin into the extracting solution, and shaking to fully and uniformly mix the medical glycerin and the extracting solution;

s5, weighing and packaging to obtain the wind-dispelling toxin-removing traditional Chinese medicine composition external tincture A.

Example 2

The formula is as follows: 120 g of groundsel, 80 g of paniculate swallowwort root, 60 g of Chinese gall and 40 g of common andrographis herb.

The preparation method in the embodiment 1 is used for preparing the external tincture B of the traditional Chinese medicine composition for eliminating wind and removing toxin.

Example 3

The formula is as follows: 100 g of groundsel, 60 g of paniculate swallowwort root, 40 g of Chinese gall and 20 g of common andrographis herb.

The preparation method in the embodiment 1 is used for preparing the external tincture C of the traditional Chinese medicine composition for dispelling wind and removing toxicity.

3000 cases are selected, wherein the patients are all old and young, the age is 86 years old and 7 years old and the disease is chronic eczema, neurodermatitis, urticaria, folliculitis and pruritus, the disease course is 32 years long and the disease course is 3 days short. The patients are randomly and averagely divided into A, B, C groups, and then respectively treated with the external tincture A, B, C of the Chinese medicinal composition for dispelling wind and removing toxicity, wherein 2147 patients are cured (symptoms disappear), 420 patients are effective (symptoms are obviously improved), 336 patients are effective (symptoms are improved), 97 patients are ineffective (diseases are not changed), and the total effective rate is 96.77%. The curing time depends on the duration of the disease, the severity of the disease, the age and whether the medicine is taken on time.

After the external tinctures A and C of the traditional Chinese medicine composition for eliminating wind and removing toxicity are used, the total effective rates are 96.90% and 95.20% respectively.

After the external tincture B of the traditional Chinese medicine composition for dispelling wind and removing toxicity is used, 625 patients with recovery (namely symptoms disappear), 312 patients with significant effect (namely symptoms are obviously improved), 45 patients with effective rate (namely symptoms are improved) and 18 patients with ineffective rate (namely symptoms are not changed), the total effective rate reaches 98.26%, and compared with A and C, the B has the best effect, and the treatment effect is shown in the following table.

TABLE 1 observation results of the patients with group B skin after using tincture B of Chinese medicinal composition with pathogenic wind dispelling, itching relieving and toxic materials removing effects

Disorders of the disease	Healing process	Show effect	Is effective	Invalidation	High efficiency
						Chronic eczema	135	59	9	5	97.59％
Neurodermatitis	127	70	10	7	96.73％
						Urticaria	121	47	8	3	98.32％
Folliculitis	109	62	7	0	100％
						Pruritus (pruritus)	133	74	11	3	98.64％
Total of	625	312	45	18	98.26％

Typical cases

Case 1

The patients: certain children, women, 78 years old, urticaria for half a month; the main symptoms are: the whole body is scattered in erythema and wheal, the pruritus is obvious, and the pruritus is aggravated especially at night. The patient is diagnosed 3 months and 14 days in 2021, and the skin mirror is examined. And (3) diagnosis: urticaria. Treatment: the tincture B for eliminating wind, relieving itching and removing toxic substance is used for 2 times per day. After one week of double diagnosis, the itching symptom is relieved, and the itching disappears after half a month of treatment. Fig. 1 shows the images of the skin before and after treatment.

Case 2

The patients: madam, woman, age 28; the main symptoms are: erythema, desquamation, blood crusting of scalp, accompanied by pruritus for 4 months. The doctor visits 10/2/2020 the patient for examination of a skin mirror. And (3) diagnosis: seborrheic dermatitis. Treatment: the tincture B for dispelling wind, relieving itching and removing toxic substance is used for 2 times per day. After one week of double diagnosis, the pruritus is relieved, and the erythema, pruritus and desquamation symptoms disappear after 4 months. Fig. 2 shows the skin mirror images before and after treatment.

Case 3

The patients: certain meng, male, age 30, folliculitis for 1 year; the main symptoms are: papulopustule mainly around the neck is accompanied by pruritus for 1 year, and the papulopustule is treated once and is easy to repeat. The patient should be examined under examination with a dermatoscope at 18 days 3 months in 2021. And (3) diagnosis: folliculitis. Treatment: the tincture B for dispelling wind, relieving itching and removing toxic substance is used for 2 times per day. After one week of double diagnosis, the symptoms basically subside, and pigmentation remains. Fig. 3 shows the skin mirror images before and after treatment.

Case 4

The patients: certain Liu, female, 19 years old, tinea corporis 1 month; the main symptoms are: when the skin is itchy and erythema for 1 month, the terbinafine spray has poor effect once used. The patient should be examined under examination with a skin mirror at 3/22/2021. And (3) diagnosis: tinea corporis. Treatment: the tincture B for dispelling wind, relieving itching and removing toxic substance is used for 2 times per day. After 2 weeks of double-diagnosis, the symptoms basically subsided and pigmentation remained. Fig. 4 shows the percutaneous mirror images before and after treatment.

Case 5

The patients: liu certain, female, 32 years old; the main symptoms are: skin itching is 6 years old, with severe lichenification of the back neck, back, front chest and forearms with itching. The patient is diagnosed in 2020, 12 months and 7 days, and examined with a skin mirror. And (3) diagnosis: neurodermatitis. Treatment: the tincture B for dispelling wind, relieving itching and removing toxic substance is used for 2 times per day. After one week of double diagnosis, the pruritus disappears, the lichenification symptom is obviously relieved in half a month, and the skin elasticity returns to normal after three months. Fig. 5 shows the percutaneous mirror images before and after treatment.

Case 6

The patients: liu somebody, female, age 70; the main symptoms are: the neck skin is dry and itchy for several days, and the doctor can see the disease 3-25 months after 2021 years and check the dermatoscope. And (3) diagnosis: eczema. Treatment: the tincture B for eliminating wind, relieving itching and removing toxic substance is used for 2 times per day. After 5 days, the symptoms disappear. Fig. 6 shows the skin mirror images before and after treatment.

The present invention is not limited to the above preferred embodiments, and any modifications, equivalent substitutions, improvements, etc. within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (3)

1. The traditional Chinese medicine composition for dispelling wind and removing toxicity is characterized by being prepared from four raw material medicines of senecio scandens, cynanchum paniculatum, gallnut and common andrographis herb, wherein the mass ratio of the four raw material medicines is (5-7): (3-5): (2-4): (1-3); the traditional Chinese medicine composition is a tincture external application medicine and is used for relieving and treating allergic skin diseases and infectious skin diseases.

2. The traditional Chinese medicine composition for dispelling wind and removing toxicity according to claim 1, which is characterized in that the mass ratio of the groundsel, the paniculate swallowwort root, the gallnut and the common andrographis herb is 6:4:3: 2.

3. A method for preparing the traditional Chinese medicine composition for dispelling wind and removing toxicity according to claim 1, which comprises the following steps:

s1, selecting high-quality raw materials according to the formula requirements and weighing for later use;

s2, putting the raw materials into alcohol, sealing and soaking for 50 days, and shaking the container once a day;

s3, filtering the soaked liquid medicine to obtain an extracting solution for later use;

s4, pouring the glycerol into the extracting solution, and shaking to mix the glycerol and the extracting solution fully and uniformly;

and S5, measuring and packaging.

Images