CN113812637A - Nutritional supplement before and after operation and application - Google Patents
Nutritional supplement before and after operation and application Download PDFInfo
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- CN113812637A CN113812637A CN202111041507.8A CN202111041507A CN113812637A CN 113812637 A CN113812637 A CN 113812637A CN 202111041507 A CN202111041507 A CN 202111041507A CN 113812637 A CN113812637 A CN 113812637A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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Abstract
The invention relates to the technical field of foods, in particular to a postoperative nutritional supplement and application thereof. The preoperative and postoperative nutritional supplement comprises snakehead peptide, black-bone chicken peptide, wheat oligopeptide, Chinese date powder, yellow fine powder, poria cocos powder, hawthorn powder, carrot powder, ginger powder, mushroom powder, purple perilla powder, tangerine peel powder, maltodextrin, resistant dextrin and ferrous gluconate, and can improve the absorption and storage of nitrogen elements in a patient with digestive tract injury and enable an organism to be in a positive nitrogen balance state; meanwhile, the plant polysaccharide in the plant components can adjust intestinal flora, thereby being beneficial to the adjustment of intestinal nutrition; the preoperative and postoperative nutritional supplement can promote synthesis and storage of albumin, prealbumin and transferrin in plasma protein, and can supplement nutrition for postoperative patients with digestive tract injury.
Description
[ technical field ] A method for producing a semiconductor device
The invention relates to the technical field of foods, in particular to a postoperative nutritional supplement and application thereof.
[ background of the invention ]
The conventional treatment mode of preoperative fasting is generally adopted in the prior art, but the treatment mode can cause a patient to enter a catabolic state prematurely, so that the postoperative recovery of the patient is not facilitated, particularly postoperative patients with damaged digestive tracts, for example, patients who undergo gastrotomy suffer from reduction in stomach volume and reduction in digestive enzyme content in the stomach after operation; patients with small bowel resection have a reduced length of the digestive tract and impaired digestive and absorptive functions after surgery; in another example, the use of anti-acid drugs to prevent stress ulcers following the digestive tract or other surgery results in a patient with limited post-operative digestive tract function. Compared with other patients, postoperative patients with digestive tract injury can eat food again after a longer time, the body of the patient is in a high catabolic state under the states of trauma and surgical stress, and the intestinal mucosa barrier injury is aggravated by a large amount of inflammatory media generated by the body of the patient, so that postoperative wound recovery is not facilitated, and therefore, the nutritional food capable of supplementing nutrition for the postoperative patients with digestive tract injury becomes a technical problem to be solved urgently.
The applicant provides a snakehead and black-bone chicken herbal composition in the prior art CN201810183288.9, and the snakehead peptide, the black-bone chicken peptide, the wheat oligopeptide, the herbal component, the soybean phospholipid and the ferrous gluconate are combined, so that the composition can accelerate wound healing and inhibit inflammatory reaction in an animal experiment stage.
[ summary of the invention ]
The invention aims to provide a postoperative nutritional supplement before and after operation and application thereof, and aims to solve the technical problem that nutrition can not be supplemented for postoperative patients with digestive tract injury in the prior art.
The technical scheme of the invention is as follows: the preoperative postoperative nutritional supplement comprises 1-20 parts by weight of snakehead peptide, 1-20 parts by weight of black-bone chicken peptide, 1-20 parts by weight of wheat oligopeptide, 0.1-15 parts by weight of Chinese date powder, 0.1-10 parts by weight of yellow fine powder, 0.1-10 parts by weight of poria cocos powder, 0.1-10 parts by weight of hawthorn powder, 0.1-8 parts by weight of carrot powder, 0.1-5 parts by weight of ginger powder, 0.1-5 parts by weight of shiitake mushroom powder, 0.1-5 parts by weight of perilla powder, 0.1-0.5 parts by weight of maltodextrin, 0.1-0.5 parts by weight of resistant dextrin and 0.01-5 parts by weight of ferrous gluconate. .
Optionally, the feed additive comprises 1-10 parts by weight of snakehead peptide, 1-10 parts by weight of black-bone chicken peptide, 1-10 parts by weight of wheat oligopeptide, 0.5-3 parts by weight of jujube powder, 0.25-2 parts by weight of rhizoma polygonati powder, 0.25-2 parts by weight of poria cocos powder, 0.25-2 parts by weight of hawthorn powder, 0.25-2 parts by weight of carrot powder, 0.1-0.5 part by weight of ginger powder, 0.5-3 parts by weight of shiitake powder, 0.5-3 parts by weight of perilla powder, 0.1-0.5 part by weight of dried orange peel powder, 0.1-0.3 part by weight of maltodextrin, 0.1-0.3 part by weight of resistant dextrin and 0.01-0.5 part by weight of ferrous gluconate.
Optionally, the feed additive comprises 1-5 parts by weight of snakehead peptide, 1-5 parts by weight of black-bone chicken peptide, 1-5 parts by weight of wheat oligopeptide, 1-2 parts by weight of Chinese date powder, 0.5-1 part by weight of yellow fine powder, 0.5-1 part by weight of poria cocos powder, 0.5-1 part by weight of hawthorn powder, 0.5-1 part by weight of carrot powder, 0.1-0.5 part by weight of ginger powder, 0.1-5 parts by weight of shiitake powder, 0.1-5 parts by weight of perilla powder, 0.1-0.5 part by weight of tangerine peel powder, 0.1-0.2 part by weight of maltodextrin, 0.1-0.2 part by weight of resistant dextrin and 0.01-0.05 part by weight of ferrous gluconate.
Optionally, the snakehead peptide is obtained according to the following steps:
pretreating, cutting and grinding the snakeheads to obtain snakehead pulp;
precooking, enzymolysis and enzyme inactivation are carried out on the snakehead peptide slurry to obtain snakehead peptide slurry;
and filtering, vacuum concentrating and drying the snakehead peptide slurry to obtain the powdery snakehead peptide.
Optionally, the black-bone chicken peptide is obtained according to the following steps:
pretreating, cutting and grinding black-bone chicken to obtain black-bone chicken slurry;
precooking gallus Domesticus slurry, performing enzymolysis and enzyme inactivation to obtain gallus Domesticus peptide slurry;
filtering, vacuum concentrating and drying the black-bone chicken peptide slurry to obtain the powdery black-bone chicken peptide.
Optionally, the particle size of the nutritional supplement is smaller than a first particle size, the first particle size being 16-60 mesh.
The other technical scheme of the invention is as follows: provides the application of the nutritional supplement before and after operation in the preparation of the nutritional food for regulating the intestinal nutrition of a patient after the operation of digestive tract injury.
The other technical scheme of the invention is as follows: the application of the nutritional supplement before and after operation in the preparation of the nutritional food for promoting the synthesis of the plasma protein of the patient after the operation of the digestive tract injury is provided, wherein the plasma protein comprises albumin, prealbumin and transferrin.
The other technical scheme of the invention is as follows: provides the application of the nutritional supplement before and after operation in the preparation of nutritional food for promoting the synthesis of plasma transferrin of a patient after the operation of digestive tract injury.
The invention has the beneficial effects that: the preoperative and postoperative nutritional supplement comprises snakehead peptide, black-bone chicken peptide, Chinese date powder, fine yellow powder, poria cocos powder, hawthorn powder, carrot powder, ginger powder, mushroom powder, purple perilla powder, tangerine peel powder, maltodextrin, resistant dextrin and ferrous gluconate, and can improve absorption and storage of nitrogen elements in a patient with digestive tract injury and enable an organism to be in a positive nitrogen balance state; meanwhile, the plant polysaccharide and the resistant dextrin in the plant components can regulate the intestinal flora, thereby being beneficial to the regulation of the intestinal nutrition; the preoperative and postoperative nutritional supplement can promote synthesis and storage of albumin, prealbumin and transferrin in plasma protein, and can supplement nutrition for postoperative patients with digestive tract injury.
[ description of the drawings ]
FIG. 1 is a comparison of the post-operative mean reduction of plasma prealbumin for groups 1 to 4 in the nutritional indicator improvement experiment of the invention;
FIG. 2 is a comparison of the post-operative mean reduction of plasma albumin in groups 1 to 4 in the nutritional indicator improvement experiment of the present invention;
fig. 3 is a comparison graph of the post-operative mean values of plasma transferrin in groups 1 to 4 in the nutritional index improvement experiment of the present invention.
[ detailed description ] embodiments
The invention is further described with reference to the following figures and embodiments.
The embodiment of the invention provides a postoperative nutritional supplement before and after operation, which comprises 1-20 parts by weight of snakehead peptide, 1-20 parts by weight of black-bone chicken peptide, 1-20 parts by weight of wheat oligopeptide, 0.1-15 parts by weight of Chinese date powder, 0.1-10 parts by weight of yellow fine powder, 0.1-10 parts by weight of poria cocos powder, 0.1-10 parts by weight of hawthorn powder, 0.1-8 parts by weight of carrot powder, 0.1-5 parts by weight of ginger powder, 0.1-5 parts by weight of shiitake powder, 0.1-5 parts by weight of purple perilla powder, 0.1-5 parts by weight of dried orange peel powder, 0.1-0.5 part by weight of maltodextrin, 0.1-0.5 part by weight of resistant dextrin and 0.01-5 parts by weight of ferrous gluconate.
In an alternative embodiment, the preoperative and postoperative nutritional supplement further comprises a flavoring agent.
The brief introduction of each component is as follows:
snakehead fish: commonly known as snakehead, snakehead (North China), raw fish (Guangdong), wealth fish (Hunan and Hubei China), high in Fe and Zn content, sweet in taste and cold in nature, and capable of tonifying spleen, benefiting qi and inducing diuresis. The snakehead peptide is obtained according to the following steps: pretreating, cutting and grinding the snakeheads to obtain snakehead pulp; precooking, enzymolysis and enzyme inactivation are carried out on the snakehead peptide slurry to obtain snakehead peptide slurry; and filtering, vacuum concentrating and drying the snakehead peptide slurry to obtain the powdery snakehead peptide. The snakehead peptide can also be extracted according to the method described in prior art CN 201810183288.9.
Black-bone chicken: the unique medicinal and edible varieties in China can be eaten independently and can be mixed into a compound medicine, and the Chinese medicinal composition has the effects of tonifying liver and kidney, replenishing qi and blood, reducing deficiency heat, treating cardiac and abdominal pain and the like. Black-bone chicken melanin contains various metal elements such as Fe, Mg, Zn, Ca and the like, and is an indole-type irregular high polymer and an indole precursor. The black-bone chicken has the functions of cleaning blood of a human body and removing garbage in the blood, can regulate the immunologic function of the human body, and has good tonifying effect on menstrual disorder caused by deficiency of qi and blood and asthenic diseases of old people: in addition, black-bone chicken contains a large amount of vitamin A and selenium, and has the effects of eliminating free radicals in vivo, resisting aging and inhibiting the growth of cancer cells. The black-bone chicken peptide is obtained according to the following steps: pretreating, cutting and grinding black-bone chicken to obtain black-bone chicken slurry; precooking gallus Domesticus slurry, performing enzymolysis and enzyme inactivation to obtain gallus Domesticus peptide slurry; filtering, vacuum concentrating and drying the black-bone chicken peptide slurry to obtain the powdery black-bone chicken peptide. The black-bone chicken peptide can also be extracted according to the method recorded in the prior art CN 201810183288.9.
Wheat oligopeptide: firstly, extracting protein from wheat protein powder, and then carrying out directional enzyme digestion and a specific small peptide separation technology to obtain a small molecular polypeptide substance.
Jujube powder: the Chinese date is sweet in taste, warm in nature, non-toxic, capable of entering heart, spleen and stomach channels, has health-preserving and health-care effects of tonifying qi and blood, benefiting spleen and stomach, dredging nine orifices, harmonizing various medicines, moistening skin and beautifying, and strengthening will and relaxing the years, is homologous in medicine and food, and contains 16 amino acids, 8 essential amino acids which cannot be synthesized by a human body, two amino acids which cannot be synthesized by an infant body, arginine and crude amino acid, various trace elements and vitamins. The main active ingredients comprise organic acid triterpenes, polysaccharide, flavone, adenosine and saponins, alkaloid and sterol.
Fine yellow powder: rhizoma polygonati is a traditional nourishing traditional Chinese medicine and is homologous in medicine and food, and the traditional Chinese medicine considers that the rhizoma polygonati has the effects of tonifying qi and yin, strengthening spleen, moistening lung and tonifying kidney. The main active ingredients comprise polygonatum polysaccharide and the like.
Poria cocos powder: poria cocos has mild medicinal properties, tonifies without being drastic, benefits without being fierce, can strengthen body resistance, and can eliminate pathogenic factors. The main active ingredients comprise polysaccharide, triterpene, etc.
Hawthorn powder: reducing accumulation, removing blood stasis, resolving stagnation, invigorating spleen and stomach, promoting digestion, and helping to recover gastrointestinal function, and contains various organic acids, flavone, saccharide, protein, trace elements, and vitamins. The main active ingredients comprise hawthorn polysaccharide and the like.
Carrot powder: is rich in saccharide, fat, volatile oil, carotene, vitamin A, vitamin B1, vitamin B2, anthocyanin, calcium, iron, etc. Has effects in promoting health, prolonging life, and indirectly eliminating cancer cells.
Ginger powder: the ginger can resist oxidation, fatigue and tumor, and has the effects of relieving various toxins, stopping vomiting (after relieving radiotherapy and chemotherapy), warming spleen, stomach, heart and lung channels, dispelling cold from middle-jiao, restoring yang, rescuing from collapse, warming lung and resolving fluid retention. The main active ingredients comprise ginger polysaccharide and the like.
Mushroom powder: the mushroom is named as "mountain delicacies" in folk, is sweet, mild and nontoxic, greatly benefits stomach qi, is rich in lentinan, various amino acids, trace elements and vitamins, and has the effects of enhancing immunity and resisting cancers.
Purple perilla powder: contains alpha-linolenic acid and perilla polysaccharide.
The pericarpium Citri Tangerinae is dried mature pericarp of Rutaceae plant Citrus reticulata Blanco and its cultivar. The main active ingredients comprise pericarpium Citri Tangerinae polysaccharide, etc.
Maltodextrin, 2: is a polysaccharide food material, and is a low conversion product between starch and starch sugar.
The resistant dextrin is processed by starch, is a low-calorie glucan which is prepared by extracting and refining indigestible components of baked dextrin by using industrial technology, and belongs to low-molecular water-soluble dietary fiber.
Ferrous gluconate: the nutrition enhancer is prepared by neutralizing gluconic acid with reduced iron.
In the preoperative and postoperative nutritional supplement of the embodiment, snakeheads and black-bone chickens are respectively used as animal protein and fish protein sources, and snakehead peptides and black-bone chicken peptides are obtained through enzymolysis. The wheat oligopeptide, the snakehead peptide and the black-bone chicken peptide provide micromolecule peptides which are easy to absorb without proteolysis, and Chinese herbal medicines such as Chinese date powder, yellow fine powder, tuckahoe powder, hawthorn powder, carrot powder, ginger powder, mushroom powder, perilla powder, tangerine peel powder and the like serving as food can be beneficial to improving the integral function of intestinal tracts, promoting intestinal tract movement, accelerating intestinal tract metabolism and increasing appetite. In addition, plant polysaccharides and various plant polysaccharides and resistant dextrin contained in the Chinese date powder, the rhizoma polygonati powder, the poria cocos powder, the hawthorn powder, the carrot powder, the ginger powder, the mushroom powder, the perilla powder and the dried orange peel powder are not absorbed by a human body, so that the intestinal flora has a certain effect on regulation of intestinal flora, and the intestinal flora has important effects on inflammation of organisms, absorption of intestinal nutrition, regulation of intestinal function and regulation of human immunity.
The nutritional supplement before and after the operation is prepared into powder, and the particle size of the nutritional supplement is smaller than a first particle size, wherein the first particle size is 16-60 meshes. The powdery preoperative and postoperative nutritional supplement belongs to a dreg-free nutritional powder, does not generate or only generates a small amount of excrement residues, and can not generate extra intestinal tract preparation burden on patients needing intestinal tract preparation under the condition of ensuring the supply of an intestinal nitrogen source.
In this embodiment, the jujube powder, rhizoma polygonati powder, poria cocos powder, hawthorn powder, carrot powder, ginger powder, mushroom powder, perilla powder and dried orange peel powder are respectively powders prepared from extracts of jujube, rhizoma polygonati, poria cocos, hawthorn, carrot, ginger, shiitake mushroom, perilla and dried orange peel. The main production process flow of various plant powders comprises the following steps: decocting → percolating → refluxing → distilling → precipitating → standing → filtering → concentrating → drying. Of course, the Chinese date, the sealwort, the tuckahoe, the hawthorn, the carrot, the ginger, the mushroom, the perilla and the dried orange peel can be respectively frozen and dried directly to obtain corresponding powder.
Therefore, the present application has conducted clinical experiments based on the animal experiments of the prior art CN201810183288.9, and found that the combination of small molecular peptides (snakehead peptide and black chicken peptide) and various plant components (jujube, polygonatum rhizome, poria cocos, hawthorn, ginger and dried orange peel) has an obvious effect of improving the specific nutritional indicators (such as plasma proteins) of the postoperative patients in addition to the efficacy of accelerating wound healing and suppressing inflammatory reactions recorded in the prior art CN201810183288.9, while the whey protein preparation does not have the above-mentioned effect of improving the specific nutritional indicators.
In an optional embodiment, the preoperative and postoperative nutritional supplement comprises 1-10 parts by weight of snakehead peptide, 1-10 parts by weight of black-bone chicken peptide, 1-10 parts by weight of wheat oligopeptide, 0.5-3 parts by weight of jujube powder, 0.25-2 parts by weight of yellow fine powder, 0.25-2 parts by weight of poria cocos powder, 0.25-2 parts by weight of hawthorn powder, 0.25-2 parts by weight of carrot powder, 0.1-0.5 part by weight of ginger powder, 0.5-3 parts by weight of shiitake powder, 0.5-3 parts by weight of perilla powder, 0.1-0.5 part by weight of dried orange peel powder, 0.1-0.3 part by weight of maltodextrin, 0.1-0.3 part by weight of resistant dextrin and 0.01-0.5 part by weight of ferrous gluconate.
In an optional embodiment, the preoperative and postoperative nutritional supplement comprises 1-5 parts by weight of snakehead peptide, 1-5 parts by weight of black-bone chicken peptide, 1-5 parts by weight of wheat oligopeptide, 1-2 parts by weight of jujube powder, 0.5-1 part by weight of yellow fine powder, 0.5-1 part by weight of poria cocos powder, 0.5-1 part by weight of hawthorn powder, 0.5-1 part by weight of carrot powder, 0.1-0.5 part by weight of ginger powder, 0.1-5 parts by weight of shiitake mushroom powder, 0.1-5 parts by weight of perilla powder, 0.1-0.5 part by weight of dried orange peel powder, 0.1-0.2 part by weight of maltodextrin, 0.1-0.2 part by weight of resistant dextrin and 0.01-0.05 part by weight of ferrous gluconate. Example 1
The embodiment provides a postoperative nutritional supplement before and after surgery, which comprises 5g of snakehead peptide, 5g of black-bone chicken peptide, 5g of wheat oligopeptide, 1.5g of Chinese date powder, 0.8g of sealwort powder, 0.8g of poria cocos powder, 0.8g of hawthorn fruit powder, 0.8g of carrot powder, 0.3g of ginger powder, 0.3g of mushroom powder, 0.3g of perilla powder, 0.3g of dried orange peel powder, 0.5g of maltodextrin, 0.5g of resistant dextrin and 0.1g of ferrous gluconate.
The snakehead peptide and the black-bone chicken peptide are prepared according to the method described in the embodiment 1 of the prior art CN201810183288.9, and are not described in detail herein.
Example 2
The embodiment provides a postoperative nutritional supplement before and after surgery, which comprises 3g of snakehead peptide, 3g of black-bone chicken peptide, 3g of wheat oligopeptide, 2g of Chinese date powder, 1g of rhizoma polygonati powder, 1g of poria cocos powder, 1g of hawthorn fruit powder, 0.5g of carrot powder, 0.5g of ginger powder, 0.5g of mushroom powder, 0.5g of perilla powder, 0.5g of dried orange peel powder, 0.1g of maltodextrin, 0.1g of resistant dextrin and 0.01g of ferrous gluconate.
Example 3
The embodiment provides a postoperative nutritional supplement before and after surgery, which comprises 2.5g of snakehead peptide, 2.5g of black-bone chicken peptide, 2.5g of wheat oligopeptide, 1g of Chinese date powder, 0.8g of rhizoma polygonati powder, 0.8g of poria cocos powder, 0.8g of hawthorn fruit powder, 0.3g of carrot powder, 0.3g of ginger powder, 0.3g of mushroom powder, 0.3g of perilla powder, 0.3g of dried orange peel powder, 0.2g of maltodextrin, 0.2g of resistant dextrin and 0.02g of ferrous gluconate.
Example 4
The embodiment provides a postoperative nutritional supplement before and after surgery, which comprises 7.5g of snakehead peptide, 7.5g of black-bone chicken peptide, 7.5g of wheat oligopeptide, 1g of Chinese date powder, 0.8g of rhizoma polygonati powder, 0.8g of poria cocos powder, 0.8g of hawthorn fruit powder, 0.3g of carrot powder, 0.3g of ginger powder, 0.3g of dried orange peel powder, 0.3g of maltodextrin, 0.3g of resistant dextrin and 0.03g of ferrous gluconate.
Example 5
The embodiment provides a postoperative nutritional supplement before and after surgery, which comprises 2.5g of snakehead peptide, 2.5g of black-bone chicken peptide, 2.5g of wheat oligopeptide, 1g of Chinese date powder, 0.8g of rhizoma polygonati powder, 0.8g of poria cocos powder, 0.8g of hawthorn fruit powder, 0.3g of carrot powder, 0.3g of ginger powder, 0.3g of mushroom powder, 0.3g of perilla powder, 0.3g of dried orange peel powder, 0.4g of maltodextrin, 0.4g of resistant dextrin and 0.04g of ferrous gluconate.
Comparative example 1
Comparative example 1 provides a whey protein preparation, either an enteral powder TP, indicated as a sole source of nutrition or as a partial nutritional supplement, or whey protein powder.
Improvement experiment of nutritional index
TABLE 1 Experimental grouping
Patients who developed gastrointestinal lesions after surgery were randomly divided into four groups (groups 1 to 4 in table 1, respectively, 20 patients each), each patient was admitted to the hospital and each patient was tested for their blood prealbumin, albumin and transferrin content on day 1, 4 and 7 post-surgery, respectively.
TABLE 2 Experimental test indexes
The results are shown in figures 1 to 3, respectively, for 9 reductions per patient per group, and for 9 reductions per group (mean of 20 patients in the group), as shown in table 2. Referring to fig. 1 and 2, data analysis shows that the mean value of the decrease of the pre-albumin and the albumin after the operation on days between groups 1 to 4 is not statistically significant (P is greater than 0.05), but as can be seen from fig. 1 and 2, the group 2 and 4 (administered with the nutritional supplement before and after the operation before the operation) are better than the group 1 and 3 (administered with the nutritional supplement before and after the operation before the operation) on the whole, and compared to the group 1 and 3, the mean value of the decrease of the pre-albumin after the operation on day 1, the mean value of the decrease of the pre-albumin after the operation on day 4, the mean value of the decrease of the pre-albumin after the operation on day 7, the mean value of the decrease of the pre-albumin after the operation on day 1, the mean value of the decrease of the pre-albumin after the operation on day 4, and the decrease of the mean value of the decrease of the post-operation on day 7 of the albumin after the operation are smaller, respectively, indicating that the nutritional supplement before and after the operation can effectively relieve the decrease of the pre-operation of the pre-albumin and the patient, improves two nutritional indexes of plasma prealbumin and plasma albumin.
Referring to fig. 3, analysis of the data on transferrin revealed that the post-operative day 7 reduction amplitude difference of transferrin was at a statistically significant threshold, with p being 0.055 ≈ 0.05, and further analysis revealed that the post-operative 1/4/7-day reduction amplitude of group 2 was significantly less than that of the other groups, and that the difference between groups 2 and 4 between days 4-7 showed an "inflection point" in the fallback. Group 3 showed a greater decrease in transferrin on day 1 post-surgery than group 1, indicating that the whey protein preparation of comparative example 1 may be detrimental to transferrin synthesis; the higher reduction values in group 4 compared to the other groups seem to be contradictory, which also suggests that the whey protein preparation of comparative example 1 may be unfavorable for transferrin synthesis, and that the concurrent intake of the snakehead peptide and the black chicken peptide in example 1 may be relatively insufficient after the whey protein preparation of comparative example 1 is taken, which may affect transferrin synthesis. Patients taking only the nutritional supplement before and after surgery (group 2) were able to effectively alleviate the transferrin reduction on day 7 after surgery, (P < 0.05). The median transferrin reduction of the patient (group 2) after the 7 th day after the operation of the nutritional supplement before and after the oral administration is 0.4700g/L, and the median transferrin reduction of the patient (group 1) without the oral administration of the silky fowl peptide group after the operation of the patient (group 1) after the 7 th day is 0.6700 g/L. The nutritional supplement before and after the operation is independently taken before the operation can effectively relieve the decrease of the transferrin of the patient after the operation and improve the nutritional index of the plasma transferrin.
In addition, from the "mean recovery" at day 7 post-surgery, we can see that group 2/4 recovered better than group 1/3, with group 2 recovering relatively best and group 4 times. The recovery mean is calculated as follows: the day 7 transferrin recovery value for each patient-the blood transferrin content detected on day 7 post-surgery-the blood transferrin content detected on day 1 post-surgery, the mean value of the day 7 transferrin recovery for each group is the mean value of the day 7 transferrin recovery values for the patients within the group 20. Meanwhile, the method further indicates that the decrease of the transferrin of the patient after the operation can be effectively relieved by independently taking the nutritional supplement before and after the operation before the operation, and the nutritional index of the plasma transferrin is improved.
The nutritional supplement before and after operation provided by the embodiment of the invention can be applied to preparation of nutritional food for regulating intestinal nutrition of patients after digestive tract injury operation.
The preoperative and postoperative nutritional supplement of the embodiment of the invention can be applied to the preparation of nutritional food for promoting the synthesis of plasma proteins of a patient after digestive tract injury, wherein the plasma proteins comprise albumin, prealbumin and transferrin.
The preoperative and postoperative nutritional supplement provided by the embodiment of the invention can be applied to preparation of a nutritional food for promoting synthesis of plasma transferrin of a patient after digestive tract injury.
While the foregoing is directed to embodiments of the present invention, it will be understood by those skilled in the art that various changes may be made without departing from the spirit and scope of the invention.
Claims (10)
1. The preoperative postoperative nutritional supplement is characterized by comprising 1-20 parts by weight of snakehead peptide, 1-20 parts by weight of black-bone chicken peptide, 1-20 parts by weight of wheat oligopeptide, 0.1-15 parts by weight of jujube powder, 0.1-10 parts by weight of yellow fine powder, 0.1-10 parts by weight of poria cocos powder, 0.1-10 parts by weight of hawthorn powder, 0.1-8 parts by weight of carrot powder, 0.1-5 parts by weight of ginger powder, 0.1-5 parts by weight of shiitake mushroom powder, 0.1-5 parts by weight of purple perilla powder, 0.1-5 parts by weight of dried orange peel powder, 0.1-0.5 part by weight of maltodextrin, 0.1-0.5 part by weight of resistant dextrin and 0.01-5 parts by weight of ferrous gluconate.
2. The preoperative and postoperative nutritional supplement of claim 1, further comprising a flavoring agent.
3. The preoperative and postoperative nutritional supplement of claim 1, comprising 1-10 parts by weight of snakehead peptide, 1-10 parts by weight of black-bone chicken peptide, 1-10 parts by weight of wheat oligopeptide, 0.5-3 parts by weight of Chinese date powder, 0.25-2 parts by weight of yellow fine powder, 0.25-2 parts by weight of poria cocos powder, 0.25-2 parts by weight of hawthorn powder, 0.25-2 parts by weight of carrot powder, 0.1-0.5 part by weight of ginger powder, 0.5-3 parts by weight of shiitake powder, 0.5-3 parts by weight of perilla powder, 0.1-0.5 part by weight of dried orange peel powder, 0.1-0.3 part by weight of maltodextrin, 0.1-0.3 part by weight of resistant dextrin and 0.01-0.5 part by weight of ferrous gluconate.
4. The preoperative and postoperative nutritional supplement of claim 1, comprising 1-5 parts by weight of snakehead peptide, 1-5 parts by weight of black-bone chicken peptide, 1-5 parts by weight of wheat oligopeptide, 1-2 parts by weight of jujube powder, 0.5-1 part by weight of yellow fine powder, 0.5-1 part by weight of poria cocos powder, 0.5-1 part by weight of hawthorn powder, 0.5-1 part by weight of carrot powder, 0.1-0.5 part by weight of ginger powder, 0.1-5 parts by weight of shiitake powder, 0.1-5 parts by weight of perilla powder, 0.1-0.5 part by weight of dried orange peel powder, 0.1-0.2 part by weight of maltodextrin, 0.1-0.2 part by weight of resistant dextrin and 0.01-0.05 part by weight of ferrous gluconate.
5. The preoperative and postoperative nutritional supplement of claim 1, wherein the snakehead peptide is obtained according to the following steps:
pretreating, cutting and grinding the snakeheads to obtain snakehead pulp;
precooking, enzymolysis and enzyme inactivation are carried out on the snakehead peptide slurry to obtain snakehead peptide slurry;
and filtering, vacuum concentrating and drying the snakehead peptide slurry to obtain the powdery snakehead peptide.
6. The preoperative and postoperative nutritional supplement of claim 1, wherein the black-bone chicken peptide is obtained by the following steps:
pretreating, cutting and grinding black-bone chicken to obtain black-bone chicken slurry;
precooking gallus Domesticus slurry, performing enzymolysis and enzyme inactivation to obtain gallus Domesticus peptide slurry;
filtering, vacuum concentrating and drying the black-bone chicken peptide slurry to obtain the powdery black-bone chicken peptide.
7. The preoperative and postoperative nutritional supplement according to any one of claims 1-6, wherein the particle size of the preoperative and postoperative nutritional supplement is smaller than a first particle size, and the first particle size is 16-60 meshes.
8. Use of a nutritional supplement according to any one of claims 1 to 6 for the preparation of a nutritional food for enteral nutrition regulation in a patient after surgery for an alimentary tract injury.
9. Use of a nutritional supplement according to any one of claims 1 to 6 for the manufacture of a nutritional food for promoting plasma protein synthesis in a patient following surgery for a post-operative injury to the digestive tract, wherein the plasma proteins comprise albumin, prealbumin and transferrin.
10. Use of a nutritional supplement according to any one of claims 1 to 6 for the manufacture of a nutritional food for promoting plasma transferrin synthesis in a patient after surgery for digestive tract injury.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114794472A (en) * | 2022-03-29 | 2022-07-29 | 厦门市中医院 | Traditional Chinese medicine nutritional composition for parenteral patients to eat orally in perioperative period |
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| CN108402459A (en) * | 2018-03-06 | 2018-08-17 | 深圳施之健生命科技有限公司 | Snakehead Gallus domesticlus brisson book on Chinese herbal medicine composition and its preparation method and application |
| CN108464386A (en) * | 2018-03-06 | 2018-08-31 | 深圳施之健生命科技有限公司 | The preparation method and snakehead Gly-His-Lys of snakehead Gly-His-Lys |
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| CN108402459A (en) * | 2018-03-06 | 2018-08-17 | 深圳施之健生命科技有限公司 | Snakehead Gallus domesticlus brisson book on Chinese herbal medicine composition and its preparation method and application |
| CN108464386A (en) * | 2018-03-06 | 2018-08-31 | 深圳施之健生命科技有限公司 | The preparation method and snakehead Gly-His-Lys of snakehead Gly-His-Lys |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114794472A (en) * | 2022-03-29 | 2022-07-29 | 厦门市中医院 | Traditional Chinese medicine nutritional composition for parenteral patients to eat orally in perioperative period |
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