CN113785844A - Aerosol for toilet disinfection foam and preparation method thereof - Google Patents
Aerosol for toilet disinfection foam and preparation method thereof Download PDFInfo
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- CN113785844A CN113785844A CN202110919552.2A CN202110919552A CN113785844A CN 113785844 A CN113785844 A CN 113785844A CN 202110919552 A CN202110919552 A CN 202110919552A CN 113785844 A CN113785844 A CN 113785844A
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- China
- Prior art keywords
- foam
- aerosol
- fomes
- toilet
- aerosol formulation
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- 239000006260 foam Substances 0.000 title claims abstract description 85
- 239000000443 aerosol Substances 0.000 title claims abstract description 44
- 238000004659 sterilization and disinfection Methods 0.000 title claims abstract description 30
- 238000002360 preparation method Methods 0.000 title claims abstract description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 18
- 239000012752 auxiliary agent Substances 0.000 claims abstract description 17
- 239000008367 deionised water Substances 0.000 claims abstract description 13
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 13
- 241000123330 Fomes fomentarius Species 0.000 claims abstract description 11
- 239000004088 foaming agent Substances 0.000 claims abstract description 8
- 239000003755 preservative agent Substances 0.000 claims abstract description 8
- 230000002335 preservative effect Effects 0.000 claims abstract description 8
- 239000004094 surface-active agent Substances 0.000 claims abstract description 8
- 239000003380 propellant Substances 0.000 claims abstract description 7
- 241000123326 Fomes Species 0.000 claims description 21
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N Propane Chemical group CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 claims description 20
- 239000000203 mixture Substances 0.000 claims description 16
- 238000009472 formulation Methods 0.000 claims description 14
- HQYALQRYBUJWDH-UHFFFAOYSA-N trimethoxy(propyl)silane Chemical compound CCC[Si](OC)(OC)OC HQYALQRYBUJWDH-UHFFFAOYSA-N 0.000 claims description 12
- -1 alkyl glycoside Chemical class 0.000 claims description 11
- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical group CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 claims description 11
- 230000000249 desinfective effect Effects 0.000 claims description 11
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical group [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 claims description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 10
- 239000001273 butane Substances 0.000 claims description 10
- 229930182470 glycoside Natural products 0.000 claims description 10
- IJDNQMDRQITEOD-UHFFFAOYSA-N n-butane Chemical compound CCCC IJDNQMDRQITEOD-UHFFFAOYSA-N 0.000 claims description 10
- OFBQJSOFQDEBGM-UHFFFAOYSA-N n-pentane Natural products CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 claims description 10
- 229940069338 potassium sorbate Drugs 0.000 claims description 10
- 235000010241 potassium sorbate Nutrition 0.000 claims description 10
- 239000004302 potassium sorbate Substances 0.000 claims description 10
- 239000001294 propane Substances 0.000 claims description 10
- 239000007788 liquid Substances 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 9
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims description 8
- 239000002202 Polyethylene glycol Substances 0.000 claims description 8
- 229940073507 cocamidopropyl betaine Drugs 0.000 claims description 8
- 229920001223 polyethylene glycol Polymers 0.000 claims description 8
- 239000000843 powder Substances 0.000 claims description 8
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 7
- 229910052782 aluminium Inorganic materials 0.000 claims description 7
- 239000000243 solution Substances 0.000 claims description 7
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 6
- 239000002253 acid Substances 0.000 claims description 6
- 239000012295 chemical reaction liquid Substances 0.000 claims description 6
- 238000011049 filling Methods 0.000 claims description 6
- 238000010438 heat treatment Methods 0.000 claims description 6
- 239000011259 mixed solution Substances 0.000 claims description 6
- 238000002156 mixing Methods 0.000 claims description 6
- 238000000926 separation method Methods 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 6
- 239000006228 supernatant Substances 0.000 claims description 6
- 238000002137 ultrasound extraction Methods 0.000 claims description 6
- 238000005303 weighing Methods 0.000 claims description 6
- 239000007864 aqueous solution Substances 0.000 claims description 4
- 238000004821 distillation Methods 0.000 claims description 4
- 238000001035 drying Methods 0.000 claims description 4
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 claims description 4
- 238000001816 cooling Methods 0.000 claims description 3
- 235000013399 edible fruits Nutrition 0.000 claims description 3
- 238000004108 freeze drying Methods 0.000 claims description 3
- 229910052757 nitrogen Inorganic materials 0.000 claims description 3
- 238000007873 sieving Methods 0.000 claims description 3
- 230000001954 sterilising effect Effects 0.000 abstract description 16
- 230000000694 effects Effects 0.000 abstract description 9
- 238000004332 deodorization Methods 0.000 abstract description 3
- 230000001580 bacterial effect Effects 0.000 description 10
- 230000000052 comparative effect Effects 0.000 description 10
- 238000012360 testing method Methods 0.000 description 9
- 230000014759 maintenance of location Effects 0.000 description 7
- 241000222122 Candida albicans Species 0.000 description 5
- 241000588724 Escherichia coli Species 0.000 description 5
- 241000191967 Staphylococcus aureus Species 0.000 description 5
- 230000000844 anti-bacterial effect Effects 0.000 description 5
- 229940095731 candida albicans Drugs 0.000 description 5
- 239000007787 solid Substances 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 241000123150 Fomitopsis pinicola Species 0.000 description 4
- 241000123247 Inonotus Species 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 239000012459 cleaning agent Substances 0.000 description 3
- 239000012141 concentrate Substances 0.000 description 3
- 230000001877 deodorizing effect Effects 0.000 description 3
- 239000000645 desinfectant Substances 0.000 description 3
- 238000005187 foaming Methods 0.000 description 3
- 239000012488 sample solution Substances 0.000 description 3
- 239000007921 spray Substances 0.000 description 3
- 238000010998 test method Methods 0.000 description 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 2
- 241000123113 Phellinus igniarius Species 0.000 description 2
- 241001604597 Pyrestini Species 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 239000003599 detergent Substances 0.000 description 2
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- 239000000194 fatty acid Substances 0.000 description 2
- 238000011056 performance test Methods 0.000 description 2
- 239000008055 phosphate buffer solution Substances 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- VZSRBBMJRBPUNF-UHFFFAOYSA-N 2-(2,3-dihydro-1H-inden-2-ylamino)-N-[3-oxo-3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propyl]pyrimidine-5-carboxamide Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)C(=O)NCCC(N1CC2=C(CC1)NN=N2)=O VZSRBBMJRBPUNF-UHFFFAOYSA-N 0.000 description 1
- WZFUQSJFWNHZHM-UHFFFAOYSA-N 2-[4-[2-(2,3-dihydro-1H-inden-2-ylamino)pyrimidin-5-yl]piperazin-1-yl]-1-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethanone Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)N1CCN(CC1)CC(=O)N1CC2=C(CC1)NN=N2 WZFUQSJFWNHZHM-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 239000001888 Peptone Substances 0.000 description 1
- 108010080698 Peptones Proteins 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 239000002518 antifoaming agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 239000006172 buffering agent Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 229910001629 magnesium chloride Inorganic materials 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000019319 peptone Nutrition 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 238000013112 stability test Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 150000003505 terpenes Chemical class 0.000 description 1
- 235000007586 terpenes Nutrition 0.000 description 1
- 238000012549 training Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
- A01N25/06—Aerosols
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/30—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/06—Unsaturated carboxylic acids or thio analogues thereof; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/01—Deodorant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/14—Disinfection, sterilisation or deodorisation of air using sprayed or atomised substances including air-liquid contact processes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/336—Polymers modified by chemical after-treatment with organic compounds containing silicon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2209/00—Aspects relating to disinfection, sterilisation or deodorisation of air
- A61L2209/20—Method-related aspects
- A61L2209/21—Use of chemical compounds for treating air or the like
Abstract
The invention provides an aerosol for toilet disinfection foam, which is prepared from the following components in percentage by weight: 10-15% of foaming agent, 0.5-1% of foam auxiliary agent, 12-16% of propellant, 5-9% of surfactant, 1-2% of preservative, 0.3-0.8% of red-spotted fomes fomentarius extract and the balance of deionized water, wherein the sum of the weight percentages of the components is 100%. The invention also provides a preparation method of the aerosol for the toilet disinfection foam. The aerosol provided by the invention has good foam stability, can effectively prevent splashing, and has good sterilization and deodorization effects.
Description
Technical Field
The invention relates to an aerosol, in particular to an aerosol for toilet disinfection foam and a preparation method thereof.
Background
Along with the continuous improvement of the living standard of people in China, the use of the flush toilet is more and more popular, and the existing flush toilet used by people generally has the problems of odor, easy splashing, easy dirt adhesion, bacteria breeding and the like. In this regard, people often use toilet cleaners in an attempt to solve these problems. The existing toilet cleaning agent generally comprises two categories of solid and liquid, wherein the solid cleaning agent mainly comprises fatty acid, fatty acid salt and alkali substances, or is added with emulsifier, disinfectant, detergent and the like to prepare a solid, and the solid is put into a water storage tank of the toilet to be slowly dissolved to release effective components to play a cleaning role, but the splashing can not be effectively prevented, and the solid cleaning agent is frequently used and replaced; the liquid detergent mainly comprises inorganic acid or organic acid, surfactant, disinfectant and the like, is poured into a closestool when in use, has the functions of cleaning and deodorizing, but has poor effects of deodorizing and sterilizing, and can not effectively prevent splashing. There is also a foam type cleanser on the market, which forms foam at the water seal of the toilet bowl to prevent the dropping feces from splashing, but the splashing prevention effect is greatly reduced due to poor stability of the foam in practical use.
Chinese patent application CN201410492710.0 discloses a toilet deodorizing and sterilizing foam liquid and a preparation method thereof, which comprises the following components in parts by weight: 30-40 parts of anionic surfactant alkyl sodium sulfonate, 6-8 parts of defoaming agent isopropanol, 3-6 parts of buffering agent citric acid, 200 parts of ethanol, 200 parts of sterilizing preservative, 100 parts of magnesium chloride, 1-2 parts of spice and 1-2 parts of water. Although the patent has a certain sterilization effect, the odor removal effect is general, the foam stability is not good, and the splashing prevention effect is not good.
Disclosure of Invention
The invention aims to provide an aerosol for toilet disinfection foam, which has good foam stability, can effectively prevent splashing and has good sterilization and deodorization effects.
In order to solve the technical problems, the technical scheme of the invention is as follows:
an aerosol for toilet disinfection foam, the aerosol being made from the following components in percentage by weight: 10-15% of foaming agent, 0.5-1% of foam auxiliary agent, 12-16% of propellant, 5-9% of surfactant, 1-2% of preservative, 0.3-0.8% of red-spotted fomes fomentarius extract and the balance of deionized water, wherein the sum of the weight percentages of the components is 100%.
Further, the foaming agent of the present invention is cocamidopropyl betaine.
Further, the foam assistant is prepared by the following steps:
adding polyethylene glycol methacrylate into a reaction bottle while stirring under the protection of nitrogen, heating to 90 ℃, adding propyl trimethoxy silane and chloroplatinic acid, heating to 115 ℃, stirring for reacting for 2 hours to obtain a reaction liquid, and distilling the reaction liquid under reduced pressure to remove unreacted propyl trimethoxy silane to obtain the foam assistant.
Furthermore, in the preparation step of the foam assistant, the mass ratio of the polyethylene glycol methacrylate to the propyl trimethoxy silane to the chloroplatinic acid is 80:72:0.5, the temperature during reduced pressure distillation is 120 ℃, and the pressure during reduced pressure distillation is-0.095 MPa.
Further, the propellant is propane and butane.
Further, the surfactant of the present invention is an alkyl glycoside.
Further, the preservative of the invention is potassium sorbate.
Further, the Inonotus erythraea extract is prepared by the following steps:
drying the fruit bodies of the red-spotted fomes fomentarius at 50 ℃, crushing, sieving with a 60-mesh sieve, collecting the undersize to obtain red-spotted fomes fomentarius powder, adding the red-spotted fomes fomentarius powder into an ethanol water solution, carrying out ultrasonic extraction at 40 ℃ for 45 minutes to obtain an extracting solution, cooling to room temperature, standing for 2 hours, carrying out centrifugal separation for 15 minutes to obtain a supernatant, and carrying out freeze drying on the supernatant to obtain the red-spotted fomes fomentarius extract.
Furthermore, in the preparation steps of the Inonotus rubra extract, the volume fraction of the ethanol aqueous solution is 80%, the weight-volume ratio of Inonotus rubra powder to the ethanol aqueous solution is 1:8g/mL, the ultrasonic power during ultrasonic extraction is 240W, and the centrifugal speed during centrifugal separation is 4000 revolutions per minute.
Another technical problem to be solved by the present invention is to provide a method for preparing the above aerosol for toilet bowl disinfectant foam.
In order to solve the technical problems, the technical scheme is as follows:
a method of preparing an aerosol formulation for a toilet disinfecting foam comprising the steps of:
(1) weighing the components according to a formula, adding a foaming agent, a foam auxiliary agent, a surfactant, a preservative and a fomes rubra extract into deionized water, and uniformly mixing at 40-50 ℃ to obtain a mixed solution;
(2) and (3) filling a propellant and the mixed liquid obtained in the step (1) into an aluminum can under the pressure of 0.5-1Mpa, and installing a valve and a nozzle to obtain the aerosol for the toilet disinfection foam.
Compared with the prior art, the invention has the following beneficial effects:
1) the foaming agent used in the invention is cocamidopropyl betaine, which has better foaming performance and antibacterial performance and can form a large amount of foam in a short time.
2) The phellinus igniarius sporocarp is subjected to ultrasonic extraction by taking an ethanol water solution as a solvent to obtain the phellinus igniarius extract which contains various active ingredients such as polysaccharide, terpenes and the like and has good antibacterial activity and odor removal performance, so that the sterilization and deodorization effects of the aerosol can be further improved.
Detailed Description
The present invention will be described in detail with reference to specific embodiments, and the exemplary embodiments and descriptions thereof herein are provided to explain the present invention but not to limit the present invention.
Example 1
An aerosol for toilet bowl disinfection foam, which is prepared from the following components in percentage by weight: 14% of cocamidopropyl betaine, 0.8% of foam assistant, 15% of propane and butane, 7% of alkyl glycoside, 1.6% of potassium sorbate, 0.5% of fomes rubra extract and the balance of deionized water, wherein the sum of the weight percentages of the components is 100%.
The foam assistant is prepared by the following steps:
adding polyethylene glycol methacrylate into a reaction bottle while stirring under the protection of nitrogen, heating to 90 ℃, adding propyl trimethoxy silane and chloroplatinic acid, wherein the mass ratio of the polyethylene glycol methacrylate to the propyl trimethoxy silane to the chloroplatinic acid is 80:72:0.5, heating to 115 ℃, stirring and reacting for 2 hours to obtain a reaction liquid, and distilling the reaction liquid under the conditions of 120 ℃ and 0.095Mpa under reduced pressure to remove unreacted propyl trimethoxy silane to obtain the foam auxiliary agent.
The fomes rubra extract is prepared by the following steps:
drying the fruit bodies of the fomes pinicola at 50 ℃, crushing, sieving with a 60-mesh sieve, collecting undersize to obtain fomes pinicola powder, adding the fomes pinicola powder into an ethanol water solution with the volume fraction of 80% according to the weight volume ratio of 1:8g/mL, performing ultrasonic extraction for 45 minutes at 40 ℃ and 240W under the ultrasonic power condition to obtain an extracting solution, cooling to room temperature, standing for 2 hours, then performing centrifugal separation for 15 minutes at the centrifugal speed of 4000 revolutions/separation to obtain a supernatant, and performing freeze drying on the supernatant to obtain the fomes pinicola extract.
The preparation method of example 1 comprises the following steps:
(1) weighing the components according to a formula, adding cocoamidopropyl betaine, a foam auxiliary agent, alkyl glycoside, potassium sorbate and a fomes rubra extract into deionized water, and uniformly mixing at 45 ℃ to obtain a mixed solution;
(2) and (2) filling propane and butane and the mixed liquid obtained in the step (1) into an aluminum tank under the pressure of 0.8Mpa, and installing a valve and a spray head to obtain the aerosol for the toilet disinfection foam.
Example 2
An aerosol for toilet bowl disinfection foam, which is prepared from the following components in percentage by weight: 12% of cocamidopropyl betaine, 0.6% of a foam assistant, 14% of propane and butane, 9% of alkyl glycoside, 1% of potassium sorbate, 0.3% of a red skin bacterium extract and the balance of deionized water, wherein the sum of the weight percentages of the components is 100%. The procedure for the preparation of the foam aid and the extract of fomes erythraea was the same as in example 1.
The preparation method of example 2 comprises the following steps:
(1) weighing the components according to a formula, adding cocoamidopropyl betaine, a foam auxiliary agent, alkyl glycoside, potassium sorbate and a fomes rubra extract into deionized water, and uniformly mixing at 40 ℃ to obtain a mixed solution;
(2) and (2) filling propane and butane and the mixed liquid obtained in the step (1) into an aluminum tank under the pressure of 0.5Mpa, and installing a valve and a spray head to obtain the aerosol for the toilet disinfection foam.
Example 3
An aerosol for toilet bowl disinfection foam, which is prepared from the following components in percentage by weight: 10% of cocamidopropyl betaine, 1% of a foam assistant, 16% of propane and butane, 8% of alkyl glycoside, 2% of potassium sorbate, 0.6% of a red-spotted fomes fungus extract and the balance of deionized water, wherein the sum of the weight percentages of the components is 100%. The procedure for the preparation of the foam aid and the extract of fomes erythraea was the same as in example 1.
The preparation method of example 3 comprises the following steps:
(1) weighing the components according to a formula, adding cocoamidopropyl betaine, a foam auxiliary agent, alkyl glycoside, potassium sorbate and a fomes rubra extract into deionized water, and uniformly mixing at 50 ℃ to obtain a mixed solution;
(2) and (3) filling propane and butane and the mixed liquid obtained in the step (1) into an aluminum tank under the pressure of 1Mpa, and installing a valve and a nozzle to obtain the aerosol for the toilet disinfection foam.
Example 4
An aerosol for toilet bowl disinfection foam, which is prepared from the following components in percentage by weight: 15% of cocamidopropyl betaine, 0.5% of a foam assistant, 12% of propane and butane, 5% of alkyl glycoside, 1.5% of potassium sorbate, 0.8% of a red-spotted fomes fungus extract and the balance of deionized water, wherein the sum of the weight percentages of the components is 100%. The procedure for the preparation of the foam aid and the extract of fomes erythraea was the same as in example 1.
The preparation method of example 4 comprises the following steps:
(1) weighing the components according to a formula, adding cocamidopropyl betaine, a foam auxiliary agent, alkyl glycoside, potassium sorbate and a fomes rubra extract into deionized water, and uniformly mixing at 48 ℃ to obtain a mixed solution;
(2) and (2) filling propane and butane and the mixed liquid obtained in the step (1) into an aluminum tank under the pressure of 0.9Mpa, and installing a valve and a spray head to obtain the aerosol for the toilet disinfection foam.
Reference example 1
The difference from example 1 is that: the components do not comprise the foam auxiliary agent, and the preparation step of the foam auxiliary agent is omitted.
Reference example 2
The difference from example 1 is that: the foaming auxiliary agent in the components is replaced by propyl trimethoxy silane, and the preparation step of the foaming auxiliary agent is omitted.
Reference example 3
The difference from example 1 is that: the components do not contain the fomes rubra extract, so that the preparation step of the fomes rubra is omitted.
Comparative example: example 1 of chinese patent application No. CN 201410492710.0.
The first experimental example: foam stability test
The test method comprises the following steps: the aerosol formulations prepared in examples 1 to 4 and reference examples 1 to 3 and the foam concentrate prepared in comparative example were placed in the same aluminum cans in a volume of 100mL, respectively, and the foam was sprayed into the measuring cylinder by pressing the same nozzle for 2 seconds, and the foam height was recorded as L1, and after standing for 2 hours, the foam height was recorded again as L2, and the foam height retention ratio was calculated according to the following formula:
foam height retention rate L2/L1X 100%
Higher foam height retention indicates better foam stability, and the test results are shown in table 1:
| foam height storage (%) | |
| Example 1 | 91.7 |
| Example 2 | 91.2 |
| Example 3 | 90.9 |
| Example 4 | 91.4 |
| Reference example 1 | 75.0 |
| Reference example 2 | 83.3 |
| Reference nutExample 3 | 88.9 |
| Comparative example | 55.6 |
TABLE 1
As can be seen from Table 1, the foam height retention rates of inventive examples 1-4 are significantly higher than those of comparative examples, indicating that the aerosol formulations prepared by the present invention have better foam stability. Compared with the example 1, the foam height retention rate of the reference example 1 is greatly reduced in comparison with the example 1 due to the fact that the partial components of the reference examples 1-3 are different from the example 1, and the foam auxiliary agent used in the invention can effectively improve the foam stability of the aerosol; the foam height retention rate of the reference example 2 is also reduced, but the reduction amplitude is smaller than that of the reference example 1, which shows that compared with the propyl trimethoxy silane which is not reacted with the polyethylene glycol methacrylate, the foam auxiliary agent prepared by reacting the propyl trimethoxy silane with the polyethylene glycol methacrylate has better effect of improving the foam stability; the foam height retention rate of reference example 3 is reduced to a small extent, which shows that the fomes erythraea extract used in the present invention can also play a certain role in improving the foam stability.
Experiment example two: sterilization Performance test
The test method comprises the following steps: the experimental bacterial tablet is escherichia coli, staphylococcus aureus and candida albicans, and the preparation process of the bacterial tablet is as follows: respectively preparing bacterial suspensions from escherichia coli, staphylococcus aureus and candida albicans tablets by using PBS (phosphate buffer solution) containing 1% peptone, then respectively dripping the bacterial suspensions on degreased cloth pieces of 1cm multiplied by 1cm, drying the degreased cloth pieces at room temperature for 1 hour to obtain the bacterial tablets, and recording the number of viable bacteria on the bacterial tablets as N1.
The aerosol prepared in example 1 and reference example 3 and the foam concentrate prepared in the comparative example were diluted 50 times with distilled water to prepare sample solutions, 5mL of the sample solution was used for each bacterial piece, the sample solutions were placed in a water bath at 20 ℃, then the bacterial pieces were added, the bacterial pieces were taken out after standing for 30 minutes, the bacterial pieces were put into a test tube containing 5mL of a neutralizer, the test tube was shaken 80 times to obtain an eluate, the number of viable bacteria was recorded as N2 in 0.5mL of the eluate, and the sterilization rate was calculated according to the following formula:
the bactericidal rate was (N1-N2)/N1 × 100%.
Higher sterilization rate indicates better sterilization performance. The test results are shown in table 2:
| sterilization ratio of Escherichia coli (%) | Staphylococcus aureus bactericidal ratio (%) | Candida albicans bactericidal rate (%) | |
| Example 1 | 99.87 | 99.92 | 98.35 |
| Reference example 3 | 92.78 | 92.84 | 89.26 |
| Comparative example | 85.56 | 86.23 | 82.39 |
TABLE 2
As can be seen from Table 2, the sterilization rates of the aerosol prepared by the method of the invention in example 1 on Escherichia coli, Staphylococcus aureus and Candida albicans are obviously higher than those of the comparative examples, and the aerosol prepared by the method of the invention has better sterilization performance. The composition of reference example 3 is different from that of example 1, compared with example 1, the sterilization rate of reference example 3 on escherichia coli, staphylococcus aureus and candida albicans is reduced a lot, and the sterilization performance of the aerosol can be effectively improved by the fomes erythrinae extract used by the invention.
Experiment example three: odor removal Performance test
The test method comprises the following steps: the experimental closestool is that 6 public latrine toilets that the average grade of stink reaches more than 4 points, calculate the average grade of stink after grading by 5 qualified smelly personnel through training, and the stink standard of grading is:
1 point, no odor;
2 points, the user feels extremely weak odor and seems to have or not;
3 minutes, the odor can be obviously smelled;
4 points, strong odor exists;
5 points, there is a nausea and intolerable odor.
The aerosol prepared in examples 1 to 4 and reference example 3 in a volume of 200mL and the foam concentrate prepared in the comparative example were uniformly sprayed on the surfaces of the 6 public toilet bowls, and after 10 minutes, 5 smellers were allowed to score again, and then the average score of the odor after the test was calculated.
The lower average odor score after the test indicates better odor removal performance, and the test results are shown in table 3:
| average odor score after test | |
| Example 1 | 1 |
| Example 2 | 1.2 |
| Example 3 | 1.2 |
| Example 4 | 1 |
| Reference example 3 | 3.0 |
| Comparative example | 3.6 |
TABLE 3
As can be seen from Table 3, the average odor scores of inventive examples 1-4 after the test are all significantly lower than those of the comparative examples, indicating that the aerosol formulations prepared by the present invention have better odor removal performance. The composition of reference example 3 is different from that of example 1, and the average odor score of reference example 3 is slightly increased compared with that of example 1, which shows that the fomes erythrinae extract used in the present invention is effective in improving the odor removing performance of the aerosol.
The foregoing embodiments are merely illustrative of the principles and utilities of the present invention and are not intended to limit the invention. Any person skilled in the art can modify or change the above-mentioned embodiments without departing from the spirit and scope of the present invention. Accordingly, it is intended that all equivalent modifications or changes which can be made by those skilled in the art without departing from the spirit and technical spirit of the present invention be covered by the claims of the present invention.
Claims (10)
1. An aerosol formulation for a toilet disinfecting foam, characterized by: the aerosol is prepared from the following components in percentage by weight: 10-15% of foaming agent, 0.5-1% of foam auxiliary agent, 12-16% of propellant, 5-9% of surfactant, 1-2% of preservative, 0.3-0.8% of red-spotted fomes fomentarius extract and the balance of deionized water, wherein the sum of the weight percentages of the components is 100%.
2. An aerosol formulation for a toilet disinfecting foam according to claim 1, wherein: the foaming agent is cocamidopropyl betaine.
3. An aerosol formulation for a toilet disinfecting foam according to claim 1, wherein: the foam auxiliary agent is prepared by the following steps:
adding polyethylene glycol methacrylate into a reaction bottle while stirring under the protection of nitrogen, heating to 90 ℃, adding propyl trimethoxy silane and chloroplatinic acid, heating to 115 ℃, stirring for reacting for 2 hours to obtain a reaction liquid, and distilling the reaction liquid under reduced pressure to remove unreacted propyl trimethoxy silane to obtain the foam assistant.
4. An aerosol formulation for a toilet disinfecting foam according to claim 1, wherein: in the preparation step of the foam assistant, the mass ratio of the polyethylene glycol methacrylate to the propyl trimethoxy silane to the chloroplatinic acid is 80:72:0.5, the temperature during reduced pressure distillation is 120 ℃, and the pressure during reduced pressure distillation is-0.095 MPa.
5. An aerosol formulation for a toilet disinfecting foam according to claim 1, wherein: the propellant is propane and butane.
6. An aerosol formulation for a toilet disinfecting foam according to claim 1, wherein: the surfactant is alkyl glycoside.
7. An aerosol formulation for a toilet disinfecting foam according to claim 1, wherein: the preservative is potassium sorbate.
8. An aerosol formulation for a toilet disinfecting foam according to claim 1, wherein: the fomes rubra extract is prepared by the following steps:
drying the fruit bodies of the red-spotted fomes fomentarius at 50 ℃, crushing, sieving with a 60-mesh sieve, collecting the undersize to obtain red-spotted fomes fomentarius powder, adding the red-spotted fomes fomentarius powder into an ethanol water solution, carrying out ultrasonic extraction at 40 ℃ for 45 minutes to obtain an extracting solution, cooling to room temperature, standing for 2 hours, carrying out centrifugal separation for 15 minutes to obtain a supernatant, and carrying out freeze drying on the supernatant to obtain the red-spotted fomes fomentarius extract.
9. An aerosol formulation for a toilet disinfecting foam according to claim 8, wherein: in the preparation steps of the fomes rubra extract, the volume fraction of an ethanol aqueous solution is 80%, the weight-volume ratio of the fomes rubra powder to the ethanol aqueous solution is 1:8g/mL, the ultrasonic power during ultrasonic extraction is 240W, and the centrifugal speed during centrifugal separation is 4000 r/min.
10. A method of preparing an aerosol formulation for a toilet disinfecting foam according to any one of claims 1 to 9, wherein: the method comprises the following steps:
(1) weighing the components according to a formula, adding a foaming agent, a foam auxiliary agent, a surfactant, a preservative and a fomes rubra extract into deionized water, and uniformly mixing at 40-50 ℃ to obtain a mixed solution;
(2) and (3) filling a propellant and the mixed liquid obtained in the step (1) into an aluminum can under the pressure of 0.5-1Mpa, and installing a valve and a nozzle to obtain the aerosol for the toilet disinfection foam.
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