CN113751168B - System for realizing preparation, extraction, analysis and detection of pharmaceutical preparation - Google Patents
System for realizing preparation, extraction, analysis and detection of pharmaceutical preparation Download PDFInfo
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- CN113751168B CN113751168B CN202110975126.0A CN202110975126A CN113751168B CN 113751168 B CN113751168 B CN 113751168B CN 202110975126 A CN202110975126 A CN 202110975126A CN 113751168 B CN113751168 B CN 113751168B
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- conveying device
- detection
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- preparation
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C21/00—Disintegrating plant with or without drying of the material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0029—Radiation
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C19/00—Other disintegrating devices or methods
- B02C19/22—Crushing mills with screw-shaped crushing means
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
- B07B—SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
- B07B1/00—Sieving, screening, sifting, or sorting solid materials using networks, gratings, grids, or the like
- B07B1/28—Moving screens not otherwise provided for, e.g. swinging, reciprocating, rocking, tilting or wobbling screens
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
- B07B—SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
- B07B1/00—Sieving, screening, sifting, or sorting solid materials using networks, gratings, grids, or the like
- B07B1/42—Drive mechanisms, regulating or controlling devices, or balancing devices, specially adapted for screens
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
- B07B—SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
- B07B1/00—Sieving, screening, sifting, or sorting solid materials using networks, gratings, grids, or the like
- B07B1/46—Constructional details of screens in general; Cleaning or heating of screens
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
- B30B11/22—Extrusion presses; Dies therefor
- B30B11/228—Extrusion presses; Dies therefor using pressing means, e.g. rollers moving over a perforated die plate
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/21—Pharmaceuticals, e.g. medicaments, artificial body parts
Abstract
The invention discloses a system for realizing preparation, extraction, analysis and detection of a pharmaceutical preparation, which comprises a screening device, wherein a crushing device is kept connected with the screening device through a first conveying device, a stirring mechanism is kept connected with the crushing device through a second conveying device, a medicament forming device is kept connected with a stirring mechanism, a drying device is kept connected with a medicament forming device, a fourth conveying device is kept connected with the drying device, a fifth conveying device is arranged on one side of the fourth conveying device and is kept connected with the fourth conveying device, a movable guide plate is arranged at the joint of the fourth conveying device and the fifth conveying device and is movably connected to one side of the fourth conveying device, and a detection mechanism is arranged on the end, far away from the fourth conveying device, of the fifth conveying device and is kept connected with the fifth conveying device. The invention provides a system for conveniently randomly sampling and detecting prepared medicaments, which is suitable for an industrial production line.
Description
Technical Field
The invention relates to the technical field of medicament preparation, in particular to a system for realizing preparation, extraction, analysis and detection of a medicinal preparation.
Background
The medicine is used for preventing, treating and diagnosing human diseases, purposefully regulating the physiological function of human and prescribing substances with indications, usage and dosage, and comprises traditional Chinese medicinal materials, traditional Chinese medicine decoction pieces, Chinese patent medicines, chemical raw material medicines and preparations thereof, antibiotics, biochemical medicines, radioactive medicines, serum vaccines, blood products, diagnostic medicines and the like. The drug reagent particles need to carry out a plurality of processes of screening, crushing, mixing with auxiliary materials, extrusion forming, drying and the like on the processed raw materials, and after drying, operators need to randomly sample and detect the drug to judge whether the batch of drugs is qualified; in the existing mode, operators need to run back and forth for sampling and detecting for many times, and the labor intensity in actual operation is high; there is also a lack of an operating system that can accomplish these objectives.
Disclosure of Invention
Therefore, in order to solve the above-mentioned deficiencies, the present invention provides a system for preparing, extracting, analyzing and detecting pharmaceutical preparations, which is suitable for industrial production lines and facilitates random sampling and detection of the prepared pharmaceutical preparations.
The invention is realized by constructing a system for realizing the preparation, extraction, analysis and detection of the pharmaceutical preparation, which comprises
The screening device is used for screening the drug raw materials;
the crushing device is connected with the screening device through the first conveying device and is used for crushing the screened raw materials;
the stirring mechanism is connected with the crushing device through a second conveying device and is used for uniformly stirring the crushed medicinal raw materials and the auxiliary materials;
the device also comprises a medicament forming device which is connected with the stirring mechanism and is used for pressing and forming the mixture of the medicinal raw materials and the auxiliary materials;
the drying device is connected with the medicament forming device and is used for conveying and drying the formed medicament;
the fourth conveying device is connected with the drying device and is used for conveying the dried and formed medicament to the next procedure;
the fifth conveying device is arranged on one side of the fourth conveying device, is connected with the fourth conveying device and acts on the sampling conveying of the medicament on the fourth conveying device to the detection device;
the movable guide plate is arranged at the joint of the fourth conveying device and the fifth conveying device, is movably connected to one side of the fourth conveying device and is used for guiding the medicament conveying direction;
the detection mechanism is arranged at the end, far away from the fourth conveying device, of the fifth conveying device, is connected with the fifth conveying device and is used for analyzing and detecting the medicament.
Further, the method comprises the following steps of; the screening device comprises a screening box, a first driving device, a first controller, a screening plate, a first discharge port and a second discharge port, wherein a first feed port integrated with the screening box is arranged at the top of the screening box, the first driving device drives the screening box to vibrate, the first controller is arranged at the top of the screening box, the screening plate is arranged in the screening box, a first discharge port connected with the screening plate is arranged at the outer side of the screening box, a second discharge port connected with the inner bottom surface of the screening box is arranged at the bottom of the side of the adjacent first discharge port, the arrangement aims at that medicine raw materials are fed into the screening box through the first feed port, the first driving device drives the screening box to vibrate, the raw materials vibrate along with the vibration, the raw materials smaller than a preset specification leak to the bottom of the screening box from a sieve pore of the screening plate and are discharged from the second discharge port, the raw materials that accord with preset specification are convenient for screen the raw materials on first conveyor is discharged from first discharge gate, improve machining efficiency, reduce intensity of labour.
Further, the method comprises the following steps of; the bottom of the screening box is provided with a buffer spring, and the purpose of the arrangement is to buffer the vibration of the screening box and improve the stability of the screening device.
Further, the method comprises the following steps of; the crushing device comprises a first support body, a feeding hopper, a crushing box, a second driving device and a crusher, wherein the second driving device is installed at the bottom of the first support body, the crushing box is arranged at the top of the first support body, the side part of the crushing box is provided with the feeding hopper communicated with the inside of the crushing box, the crusher is connected with the crushing box in a rotating mode, the second driving device drives the crusher to rotate, the purpose of the arrangement is that the first conveying device puts screened raw materials into the crushing box from the feeding hopper, and the second driving device drives the crusher to crush the raw materials entering the crushing box.
Further, the method comprises the following steps of; first support body middle part is provided with first grinding vessel, and first grinding vessel communicates through first connecting pipe and crushing bottom of the case portion, first grinding vessel internal rotation is connected with first grinding screw, and second drive arrangement drives first grinding screw and rotates, and the aim at of this setting, in the raw materials after smashing enter into first grinding vessel through first connecting pipe, second drive arrangement drives first grinding screw and rotates, grinds the raw materials after smashing and drives it and march, has improved the fineness of smashing the raw materials.
Further, the method comprises the following steps of; first support body bottom is provided with the second grinding vessel, through second connecting pipe and first grinding vessel intercommunication, the second grinding vessel internal rotation is connected with the second and grinds the screw rod, and second drive arrangement drive second grinds the screw rod and rotates, second grinding vessel one end and second conveyor intercommunication, the aim at of this setting, first grinding screw bring the raw materials into in the second grinding vessel through the second connecting pipe, and second drive arrangement drives the second and grinds the screw rod and rotate, further grinds medicine raw materials, through the two-stage grinding back, medicine raw materials granule is more fine and smooth.
Further, the method comprises the following steps of; rabbling mechanism includes stirring storehouse, third drive arrangement and agitator, stirring storehouse upper portion opening, the bottom is provided with the third discharge gate, installs the valve in the third discharge gate, stirring storehouse side-mounting has third drive arrangement, the stirring storehouse internal rotation is connected with the agitator, and third drive arrangement drive agitator rotates, and the aim at of this setting, in the medicinal raw materials after reducing mechanism smashes brings into the stirring storehouse through second conveyor, and the auxiliary material drops into the stirring storehouse in through the external device of throwing, and third drive arrangement drive agitator rotates, stirs medicinal raw materials and auxiliary material, discharges from the third discharge gate after the stirring.
Further, the method comprises the following steps of; the medicament forming device comprises a second frame body, a fourth driving device, a bin, a forming plate and an extrusion roller, wherein the fourth driving device and the bin are installed at the top of the second frame body, a second feeding hole integrated with the bin is formed in the top of the bin, a fourth discharging hole is formed in the bottom of the side face of the bin, the forming plate is installed inside the bin and above the fourth discharging hole, the extrusion roller in contact with the upper end face of the forming plate is arranged on the upper end face of the forming plate, the extrusion roller is rotationally connected with the forming plate, the bin and the second frame body through a connecting shaft, the fourth driving device drives the connecting shaft to rotate, a baffle plate is arranged inside the bin, the baffle plate is fixedly installed on the side portion of the fourth discharging hole, a guide chute connected with the lower end face of the fourth discharging hole is arranged on the outer side of the bin, sieve holes are formed in the guide chute, and the purpose of the arrangement is that the medicament after being stirred is injected onto the forming plate in the bin through the second feeding hole, fourth drive arrangement drive squeeze roll rotates, extrude the medicament on the profiled sheeting, extrude the medicament from the shaping hole of profiled sheeting, the striker plate scrapes the shaping medicament from the profiled sheeting to the bottom plate of feed bin on, the bottom plate is coaxial with the squeeze roll, rotate along with the squeeze roll, medicament on the bottom plate rotates thereupon, until rotating to the striker plate position, the motion is blockked by the striker plate, along with the medicament accumulation, the medicament is extruded the fourth discharge gate, and discharge on drying device along the baffle box, be less than the medicament granule of predetermineeing the specification and sieve from the sieve mesh, be convenient for sieve the medicament granule, reduce intensity of labour.
Further, the method comprises the following steps of; drying device includes third conveyor, the cover body, drying-machine and bactericidal lamp, be provided with the cover body on the third conveyor, the cover body and third conveyor top both sides fixed connection, the drying-machine is installed at cover body top, and the air outlet communicates with cover internal portion, and cover internal portion top is provided with the bactericidal lamp, and the aim at of this setting, third conveyor drive the medicament granule and advance to the cover internal, and the drying-machine drives the air flow, and to the air heating that flows, blow to the medicament granule simultaneously, dries the medicament granule, has improved drying efficiency, and the bactericidal lamp shines the medicament granule, disinfects the medicament granule, improves the security of medicament granule.
Further, the method comprises the following steps of; the detection mechanism comprises a sixth conveying device, a detection instrument, a second controller, an electric box and a signal lamp, wherein the sixth conveying device is connected with a fifth conveying device, the electric box and the second controller are arranged on the lateral portion of the sixth conveying device, the detection instrument is installed on the sixth conveying device and is connected with the two sides of the sixth conveying device, the detection instrument aims to convey sampled medicament particles into the detection instrument, the detection instrument detects and judges the medicament particles and uploads a detection value and a detection result to a terminal, and the signal lamp contains at least two colors of light and is used for representing different working states of detection laser.
The invention has the following advantages: the whole system of the invention has reasonable layout design, the processed raw materials are put into a screening device, the raw materials are conveyed into a crushing device for crushing through a first conveying device after being screened by the screening device, the crushed raw materials are discharged into a second conveying device and conveyed into a stirring mechanism through the second conveying device, meanwhile, auxiliary materials are put into a stirring mechanism through external feeding laser, the stirring mechanism uniformly stirs the raw materials and the auxiliary materials and then discharges the raw materials and the auxiliary materials into a medicament forming device for extrusion forming, the formed medicament particles are discharged into a drying device for drying moisture and conveyed to the next process through a fourth conveying device, the movable guide plate is stirred to rotate without a preset time interval, the medicament particles are guided to a fifth conveying device at the side part, the fifth conveying device conveys the medicament particles to a detection mechanism for detection, so that the prepared medicament can be randomly sampled and detected, is suitable for industrial production lines.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a front view of the present invention;
FIG. 3 is a side view of the present invention;
FIG. 4 is a top view of the present invention;
FIG. 5 is a schematic view of the construction of the screening apparatus;
FIG. 6 is a schematic view of the internal structure of the screening apparatus;
FIG. 7 is a schematic view of the construction of the crushing apparatus;
FIG. 8 is a schematic view showing the internal structure of the crushing apparatus;
FIG. 9 is a schematic view of the internal structure of the stirring mechanism;
FIG. 10 is a schematic view of the structure of the medicament forming device;
fig. 11 is a schematic view of the internal structure of the drug forming device;
FIG. 12 is a sectional view A-A of FIG. 11;
FIG. 13 is a cross-sectional view B-B of FIG. 11;
fig. 14 is a schematic structural view of the drying apparatus;
fig. 15 is an internal structure view of the drying apparatus;
fig. 16 is a schematic configuration diagram of the detection mechanism.
In the figure: 1. a screening device; 1-1, screening box; 1-2, a first driving device; 1-3, a first feed inlet; 1-4, a buffer spring; 1-5, a first discharge port; 1-6, a first controller; 1-7, screening plate; 1-8, a second discharge port; 2. a first conveying device; 3. a crushing device; 3-1, a first frame body; 3-2, a feed hopper; 3-3, crushing box; 3-4, a first grinding cylinder; 3-5, a second grinding cylinder; 3-6, a second driving device; 3-7, a first grinding screw; 3-8, a second grinding screw rod; 3-9, a pulverizer; 3-10, a first connecting pipe; 3-11, a second connecting pipe; 4. a second conveying device; 5. a crushing mechanism; 5-1, a third driving device; 5-2, a stirring bin; 5-3, a stirrer; 5-4, a third discharge hole; 6. a medicament forming device; 6-1, a second frame body; 6-2, a fourth driving device; 6-3, a storage bin; 6-4, a second feed inlet; 6-5, a material guide groove; 6-6, sieve mesh; 6-7, forming a plate; 6-8, extruding roller; 6-9, a connecting shaft; 6-10 parts of a material baffle plate; 7. a drying device; 7-1, a third conveying device; 7-2, a cover body; 7-3, a dryer; 7-4, a germicidal lamp; 8. a fourth conveying device; 9. a fifth conveying device; 10. a movable guide plate; 11. a detection mechanism; 11-1, a sixth conveying device; 11-2, detecting an instrument; 11-3, an electric box; 11-4, a second controller; 11-5 and a signal lamp.
Detailed Description
The present invention will be described in detail with reference to fig. 1 to 16, and the technical solutions in the embodiments of the present invention will be clearly and completely described, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be obtained by a person skilled in the art without making any creative effort based on the embodiments in the present invention, belong to the protection scope of the present invention.
The invention provides a system for realizing preparation, extraction, analysis and detection of a pharmaceutical preparation by improving, and as shown in figures 1-4, the system comprises a screening device 1, which is used for screening pharmaceutical raw materials;
the crushing device 3 is connected with the screening device 1 through the first conveying device 2, and the crushing device 3 is used for crushing the screened raw materials;
the stirring mechanism 5 is connected with the crushing device 3 through a second conveying device 4 and is used for uniformly stirring the crushed medicinal raw materials and the auxiliary materials;
the device also comprises a medicament forming device 6, wherein the medicament forming device 6 is connected with the stirring mechanism 5 and is used for pressing and forming the mixture of the medicinal raw materials and the auxiliary materials;
the drying device 7 is connected with the medicament forming device 6 and is used for conveying and drying the formed medicament;
the drying device is characterized by further comprising a fourth conveying device 8, wherein the fourth conveying device 8 is connected with the drying device 7 and is used for conveying the dried and formed medicament to the next process;
the device also comprises a fifth conveying device 9, wherein the fifth conveying device 9 is arranged on one side of the fourth conveying device 8, is connected with the fourth conveying device 8, and acts on the detection device 11 for sampling and conveying the medicament on the fourth conveying device 8;
the medicine conveying device is characterized by further comprising a movable guide plate 10, wherein the movable guide plate 10 is arranged at the joint of the fourth conveying device 8 and the fifth conveying device 9, is movably connected to one side of the fourth conveying device 8, and is used for guiding the medicine conveying direction;
the device further comprises a detection mechanism 11, wherein the detection mechanism 11 is arranged at the end, far away from the fourth conveying device 8, of the fifth conveying device 9, is connected with the fifth conveying device 9 in a maintaining mode, and is used for analyzing and detecting the medicament.
When the invention is implemented, the processed raw materials are put into a screening device 1, the raw materials are screened by the screening device 1 and then are conveyed into a crushing device 3 for crushing through a first conveying device 2, the crushed raw materials are discharged into a second conveying device 4 and conveyed into a stirring mechanism 5 through the second conveying device 4, meanwhile, auxiliary materials are put into the stirring mechanism 5 through external feeding laser, the stirring mechanism 5 uniformly stirs the raw materials and the auxiliary materials and then discharges the raw materials and the auxiliary materials into a medicament forming device 6 for extrusion forming, the formed medicament particles are discharged into a drying device 7 for drying moisture and conveyed to the next procedure through a fourth conveying device 8, the movable guide plate 10 is stirred to rotate without intervals of preset time periods, the medicament particles are guided to a fifth conveying device 10 on the side part, the medicament particles are conveyed to a detection mechanism 11 by the fifth conveying device 10 for detection, so that the prepared medicament can be randomly sampled and detected, is suitable for industrial production lines.
In this embodiment, as shown in fig. 5 to 6, the screening apparatus 1 includes a screening box 1-1, a first driving device 1-2, a first controller 1-6, a screening plate 1-7, a first discharge port 1-5 and a second discharge port 1-8, the top of the screening box 1-1 is provided with a first feed port 1-3 integrated with the screening box 1-1, the first driving device 1-2 is installed at the top of the screening box 1-1, the first driving device 1-2 drives the screening box 1-1 to vibrate, the top of the screening box 1-1 is provided with the first controller 1-6, the screening plate 1-7 is installed inside the screening box 1-1, the first discharge port 1-5 connected with the screening plate 1-7 is installed at the outer side, the bottom of the side of the adjacent first discharge port 1-5 is provided with an inner bottom connected with the bottom of the screening box 1-1 The second discharge port 1-8 is arranged, and aims to put the medicine raw materials into the screening box 1-1 through the first feed port 1-3, the first driving device 1-2 drives the screening box 1-1 to vibrate, the raw materials vibrate along with the vibration, the raw materials smaller than the preset specification are leaked to the bottom of the screening box 1-1 from the screening plate 1-7 sieve meshes and are discharged from the second discharge port 1-8, and the raw materials meeting the preset specification are discharged to the first conveying device 1 from the first discharge port 1-5, so that the raw materials are conveniently screened, the processing efficiency is improved, and the labor intensity is reduced.
In the present embodiment, as shown in fig. 5 to 6, a buffer spring 1-4 is provided at the bottom of the screening box 1-1, and the purpose of this arrangement is to buffer the vibration of the screening box 1-1 and improve the stability of the screening apparatus 1.
In this embodiment, as shown in fig. 7 to 8, the crushing apparatus 3 includes a first frame 3-1, a feeding hopper 3-2, a crushing box 3-3, a second driving device 3-6 and a crusher 3-9, the second driving device 3-6 is installed at the bottom of the first frame 3-1, the crushing box 3-3 is installed at the top, the feeding hopper 3-2 communicated with the inside of the crushing box 3-3 is installed at the side of the crushing box 3-3, the crusher 3-9 is rotatably connected to the crushing box 3-3, the second driving device 3-6 drives the crusher 3-9 to rotate, the arrangement is such that the first conveying device 2 feeds the screened raw material from the feeding hopper 3-2 into the crushing box 3-3, the second driving device 3-6 drives the crusher 3-9, the raw material introduced into the crushing tank 3-3 is crushed.
In this embodiment, as shown in fig. 7 to 8, a first grinding cylinder 3-4 is disposed in the middle of the first frame 3-1, the first grinding cylinder 3-4 is communicated with the bottom of the pulverizing box 3-3 through a first connecting pipe 3-10, a first grinding screw 3-7 is rotatably connected to the first grinding cylinder 3-4, and a second driving device 3-6 drives the first grinding screw 3-7 to rotate, so that the pulverized raw material enters the first grinding cylinder 3-4 through the first connecting pipe 3-10, and the second driving device 3-6 drives the first grinding screw 3-7 to rotate, so as to grind and drive the pulverized raw material to advance, thereby improving the fineness of the pulverized raw material.
In this embodiment, as shown in fig. 7 to 8, a second grinding cylinder 3-5 is disposed at the bottom of the first frame body 3-1, and is communicated with the first grinding cylinder 3-4 through a second connecting pipe 3-11, a second grinding screw 3-8 is rotatably connected to the second grinding cylinder 3-5, a second driving device 3-6 drives the second grinding screw 3-8 to rotate, and one end of the second grinding cylinder is communicated with the second conveying device 4, so that the first grinding screw 3-7 brings the raw material into the second grinding cylinder 3-5 through the second connecting pipe 3-11, and the second driving device 3-6 drives the second grinding screw 3-8 to rotate, so as to further grind the raw material, and after two-stage grinding, the raw material particles are finer.
In this embodiment, as shown in fig. 9, the stirring mechanism 5 includes a stirring bin 5-2, a third driving device 5-1 and a stirrer 5-3, the stirring bin 5-2 has an opening at the upper portion, a third discharge port 5-4 is provided at the bottom, a valve is installed in the third discharge port 5-4, a third driving device 5-1 is installed on the side surface of the stirring bin 5-2, the stirrer 5-3 is rotatably connected to the stirring bin 5-2, the third driving device 5-1 drives the stirrer 5-3 to rotate, the arrangement is such that the raw material of the medicine crushed by the crushing device 3 is carried into the stirring bin 5-2 through the second conveying device 4, the auxiliary material is fed into the stirring bin 5-2 through an external feeding device, and the stirrer 5-3 is driven to rotate by the third driving device 5-1, stirring the medicine raw materials and the auxiliary materials, and discharging from a third discharge port 5-4 after uniformly stirring.
In this embodiment, as shown in fig. 10 to 13, the drug forming device 6 includes a second frame body 6-1, a fourth driving device 6-2, a bin 6-3, a forming plate 6-7 and an extrusion roller 6-8, the fourth driving device 6-2 and the bin 6-3 are installed on the top of the second frame body 6-1, the second feed inlet 6-4 integrated with the bin 6-3 is installed on the top of the bin 6-3, the fourth discharge outlet is installed on the bottom of the side surface, the forming plate 6-7 is installed inside the bin 6-3 and above the fourth discharge outlet, the extrusion roller 6-8 contacting with the upper end surface of the forming plate 6-7 is installed on the upper end surface of the forming plate 6-7, the bin 6-3 and the second frame body 6-1 are rotatably connected through a connecting shaft 6-9 by the extrusion roller 6-8, the fourth driving device 6-2 drives the connecting shaft 6-9 to rotate, a material baffle 6-10 is arranged inside the bin 6-3 and fixedly installed on the side part of the fourth discharge port, a material guide chute 6-5 connected with the lower end face of the fourth discharge port is arranged on the outer side of the bin 6-3, a sieve pore 6-6 is arranged on the material guide chute 6-5, the arrangement aims at injecting the stirred medicament onto the forming plate 6-7 in the bin 6-3 through the second feed port 6-4, the fourth driving device 6-2 drives the extrusion roller 6-8 to rotate to extrude the medicament on the forming plate 6-7, the medicament is extruded from the forming hole of the forming plate 6-7, and the material baffle 6-10 scrapes the formed medicament off the forming plate 6-7 to the bottom plate of the bin 6-3, the bottom plate is coaxial with the squeezing rollers 6-8 and rotates along with the squeezing rollers 6-8, the medicament on the bottom plate rotates along with the squeezing rollers, when the bottom plate rotates to the positions of the material blocking plates 6-10, the movement is blocked by the material blocking plates 6-10, the medicament is extruded out of the fourth discharge port along with medicament accumulation, the medicament is discharged onto the drying device 7 along the material guide grooves 6-5, medicament particles smaller than the preset specification are screened out of the sieve holes 6-6, the medicament particles are conveniently screened, and the labor intensity is reduced.
In this embodiment, as shown in fig. 14 to 15, the drying device 7 includes a third conveying device 7-1, a cover 7-2, a dryer 7-3, and a germicidal lamp 7-4, the cover 7-2 is disposed on the third conveying device 7-1, the cover 7-2 is fixedly connected to two sides of the top of the third conveying device 7-1, the dryer 7-3 is mounted on the top of the cover 7-2, the air outlet is communicated with the inside of the cover 7-2, and the germicidal lamp 7-4 is disposed on the top of the inside of the cover 7-2, which is configured to drive the third conveying device 7-1 to drive the medicament particles to move into the cover 7-2, the dryer 7-3 drives air to flow, and at the same time, heats the flowing air and blows the air to the medicament particles, so as to dry the medicament particles, thereby improving drying efficiency, the sterilizing lamp 7-4 irradiates the medicament particles to sterilize the medicament particles, so that the safety of the medicament particles is improved.
In this embodiment, as shown in fig. 16, the detecting mechanism includes a sixth conveying device 11-1, a detecting device 11-2, a second controller 11-4, an electrical box 11-3 and a signal lamp 11-5, the sixth conveying device 11-1 is connected with the fifth conveying device 9, the electrical box 11-3 and the second controller 11-4 are arranged on the side of the sixth conveying device 11-1, the detecting device 11-2 is mounted on the sixth conveying device 11-1 and connected with both sides of the sixth conveying device 11-1, the arrangement is that the sixth conveying device 11 conveys sampled medicament particles into the detecting device 11-2, the detecting device 11-2 detects and judges the medicament particles and uploads the detected value and the detected result to the terminal, the signal lamp 11-5 comprises at least two colors of light for indicating different working states of the detection laser 11.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (10)
1. A system for realizing preparation, extraction, analysis and detection of a medicinal preparation is characterized in that: comprises a screening device (1) which is used for screening the raw materials of the medicine;
the device is characterized by further comprising a crushing device (3), wherein the crushing device (3) is kept connected with the screening device (1) through a first conveying device (2), and the crushing device (3) is used for crushing the screened raw materials;
the device is characterized by also comprising a stirring mechanism (5), wherein the stirring mechanism (5) is kept connected with the crushing device (3) through a second conveying device (4) and is used for uniformly stirring the crushed medicinal raw materials and auxiliary materials;
the device is characterized by also comprising a medicament forming device (6), wherein the medicament forming device (6) is connected with the stirring mechanism (5) and is used for pressing and forming the mixture of the medicinal raw materials and the auxiliary materials;
the drying device (7) is connected with the medicament forming device (6) and is used for conveying and drying the formed medicament;
the drying device is characterized by further comprising a fourth conveying device (8), wherein the fourth conveying device (8) is connected with the drying device (7) and is used for conveying the dried and formed medicament to the next process;
the medicine sampling and conveying device further comprises a fifth conveying device (9), wherein the fifth conveying device (9) is arranged on one side of the fourth conveying device (8), is connected with the fourth conveying device (8) in a maintaining mode, and acts on a medicine sampling and conveying mechanism (11) on the fourth conveying device (8);
the medicine conveying device is characterized by further comprising a movable guide plate (10), wherein the movable guide plate (10) is arranged at the joint of the fourth conveying device (8) and the fifth conveying device (9), is movably connected to one side of the fourth conveying device (8), and is used for guiding the medicine conveying direction;
the medicine feeding device is characterized by further comprising a detection mechanism (11), wherein the detection mechanism (11) is arranged at the end, far away from the fourth conveying device (8), of the fifth conveying device (9), is connected with the fifth conveying device (9) in a maintaining mode and is used for analyzing and detecting the medicines.
2. The system for realizing the preparation, extraction, analysis and detection of the pharmaceutical preparation as claimed in claim 1, wherein: the screening device (1) comprises a screening box (1-1), a first driving device (1-2), a first controller (1-6), a screening plate (1-7), a first discharge hole (1-5) and a second discharge hole (1-8), a first feed port (1-3) integrated with the screening box (1-1) is arranged at the top of the screening box (1-1), the first driving device (1-2) is installed at the top of the screening box (1-1), the first driving device (1-2) drives the screening box (1-1) to vibrate, the first controller (1-6) is installed at the top of the screening box (1-1), the screening plate (1-7) is arranged in the screening box (1-1), the first discharge hole (1-5) connected with the screening plate (1-7) is arranged at the outer side part, a second discharge port (1-8) connected with the inner bottom surface of the screening box (1-1) is arranged at the bottom of the side of the adjacent first discharge port (1-5).
3. The system for realizing the preparation, extraction, analysis and detection of the pharmaceutical preparation as claimed in claim 2, wherein: and a buffer spring (1-4) is arranged at the bottom of the screening box (1-1).
4. The system for realizing the preparation, extraction, analysis and detection of the pharmaceutical preparation as claimed in claim 1, wherein: the crushing device (3) comprises a first frame body (3-1), a feed hopper (3-2), a crushing box (3-3), a second driving device (3-6) and a crusher (3-9), wherein the second driving device (3-6) is installed at the bottom of the first frame body (3-1), the crushing box (3-3) is arranged at the top of the first frame body, the feed hopper (3-2) communicated with the inside of the crushing box (3-3) is arranged at the side part of the crushing box (3-3), the crusher (3-9) is rotationally connected in the crushing box (3-3), and the second driving device (3-6) drives the crusher (3-9) to rotate.
5. The system for realizing the preparation, extraction, analysis and detection of the pharmaceutical preparation as claimed in claim 4, wherein: the grinding device is characterized in that a first grinding cylinder (3-4) is arranged in the middle of the first frame body (3-1), the first grinding cylinder (3-4) is communicated with the bottom of the crushing box (3-3) through a first connecting pipe (3-10), a first grinding screw (3-7) is connected in the first grinding cylinder (3-4) in a rotating mode, and a second driving device (3-6) drives the first grinding screw (3-7) to rotate.
6. The system for realizing the preparation, extraction, analysis and detection of the pharmaceutical preparation as claimed in claim 4, wherein: the grinding device is characterized in that a second grinding cylinder (3-5) is arranged at the bottom of the first frame body (3-1) and communicated with the first grinding cylinder (3-4) through a second connecting pipe (3-11), a second grinding screw (3-8) is connected in the second grinding cylinder (3-5) in a rotating mode, a second driving device (3-6) drives the second grinding screw (3-8) to rotate, and one end of the second grinding cylinder is communicated with the second conveying device (4).
7. The system for realizing the preparation, extraction, analysis and detection of the pharmaceutical preparation as claimed in claim 1, wherein: stirring mechanism (5) are including stirring storehouse (5-2), third drive arrangement (5-1) and agitator (5-3), stirring storehouse (5-2) upper portion opening, the bottom is provided with third discharge gate (5-4), installs the valve in third discharge gate (5-4), stirring storehouse (5-2) side-mounting has third drive arrangement (5-1), stirring storehouse (5-2) internal rotation is connected with agitator (5-3), and third drive arrangement (5-1) drive agitator (5-3) rotate.
8. The system for realizing the preparation, extraction, analysis and detection of the pharmaceutical preparation as claimed in claim 1, wherein: medicament forming device (6) includes second support body (6-1), fourth drive arrangement (6-2), feed bin (6-3), profiled sheeting (6-7) and squeeze roll (6-8), and fourth drive arrangement (6-2) and feed bin (6-3) are installed at second support body (6-1) top, feed bin (6-3) top is provided with second feed inlet (6-4) integrative with it, and the side bottom is provided with the fourth discharge gate, profiled sheeting (6-7) are installed to inside, fourth discharge gate top of feed bin (6-3), profiled sheeting (6-7) up end is provided with squeeze roll (6-8) with profiled sheeting (6-7) up end contact, squeeze roll (6-8) through connecting axle (6-9) and profiled sheeting (6-7), The feed bin (6-3) and the second frame body (6-1) are rotatably connected, the fourth driving device (6-2) drives the connecting shaft (6-9) to rotate, a material baffle (6-10) is arranged inside the feed bin (6-3), the material baffle is fixedly mounted on the side portion of the fourth discharge port, a guide chute (6-5) connected with the lower end face of the fourth discharge port is arranged on the outer side of the feed bin (6-3), and sieve holes (6-6) are formed in the guide chute (6-5).
9. The system for realizing the preparation, extraction, analysis and detection of pharmaceutical preparations according to claim 1, wherein: the drying device (7) comprises a third conveying device (7-1), a cover body (7-2), a dryer (7-3) and a bactericidal lamp (7-4), wherein the cover body (7-2) is arranged on the third conveying device (7-1), the cover body (7-2) is fixedly connected with two sides of the top of the third conveying device (7-1), the dryer (7-3) is installed at the top of the cover body (7-2), an air outlet is communicated with the interior of the cover body (7-2), and the bactericidal lamp (7-4) is arranged at the top of the interior of the cover body (7-2).
10. The system for realizing the preparation, extraction, analysis and detection of the pharmaceutical preparation as claimed in claim 1, wherein: the detection mechanism comprises a sixth conveying device (11-1), a detection instrument (11-2), a second controller (11-4), an electric box (11-3) and a signal lamp (11-5), wherein the sixth conveying device (11-1) is connected with the fifth conveying device (9) in a maintaining mode, the electric box (11-3) and the second controller (11-4) are arranged on the side portion of the sixth conveying device (11-1), and the detection instrument (11-2) is installed on the sixth conveying device (11-1) and is connected with the two sides of the sixth conveying device (11-1) in a maintaining mode.
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| CN202110975126.0A CN113751168B (en) | 2021-08-24 | 2021-08-24 | System for realizing preparation, extraction, analysis and detection of pharmaceutical preparation |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102407186B (en) * | 2011-11-28 | 2013-08-21 | 河南省康星药业股份有限公司 | Chinese medicine ultrafine powder screening linkage system |
| CN204329537U (en) * | 2014-12-03 | 2015-05-13 | 万文静 | A kind of efficient Chinese medicine drying sterilizing tank |
| CN107876168A (en) * | 2017-10-26 | 2018-04-06 | 郑州郑先医药科技有限公司 | A kind of mobile medical pulverizing medicinal materials drying device |
| CN108607656B (en) * | 2018-04-11 | 2019-11-12 | 陈雨薇 | A kind of being made into one of Chinese herbal medicine medicinal powder equipment |
| CN210632241U (en) * | 2019-08-13 | 2020-05-29 | 禹州市润之堂药业有限公司 | Chinese-medicinal material reducing mechanism |
| CN111069112B (en) * | 2020-01-20 | 2021-03-02 | 吉林省摆渡中医药健康产业园有限公司 | Preparation device for traditional Chinese medicine for treating diabetes |
| CN111992318B (en) * | 2020-08-05 | 2021-12-21 | 饶从相 | Mixing process for traditional Chinese medicine powder |
| CN113262165A (en) * | 2021-05-19 | 2021-08-17 | 李惟妙 | Automatic pharmaceutical production line and process |
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