CN113648403A - Medicine for recovering normal conduction function of nerves and preparation method thereof - Google Patents

Medicine for recovering normal conduction function of nerves and preparation method thereof Download PDF

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CN113648403A
CN113648403A CN202111067303.1A CN202111067303A CN113648403A CN 113648403 A CN113648403 A CN 113648403A CN 202111067303 A CN202111067303 A CN 202111067303A CN 113648403 A CN113648403 A CN 113648403A
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parts
pouring
vitamin
mixture
medicine
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叶茂
郑龙太
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Sichuan Science City Hospital
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Sichuan Science City Hospital
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    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K31/4015Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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Abstract

The invention discloses a medicine for recovering normal conduction function of nerves, which comprises the following raw materials in parts by weight: 5-10 parts of ligusticum wallichii, 5-10 parts of scutellaria baicalensis, 3-7 parts of nux vomica, 2-8 parts of gastrodia elata, 4-9 parts of angelica sinensis, 5-7 parts of lycopodium clavatum, 1-3 parts of rose, 5-10 parts of salvia miltiorrhiza, 6-11 parts of garden balsam stem, 2-6 parts of safflower, 7-9 parts of scorpion, 2-5 parts of nucleolus, 4-9 parts of astragalus membranaceus, 15-10 parts of vitamin B, 125-10 parts of vitamin B, 10-20 parts of ethanol, 6-12 parts of nerve growth factor, 4-9 parts of ganglioside, 3-7 parts of oryzanol, 3-7 parts of Naofukang and 2-6 parts of citicoline, and relates to the technical field of medicines. The preparation method of the medicine for recovering the normal conduction function of the nerve can treat sleep disorder caused by nerve injury, can relieve whole body muscle stiffness caused by nerve injury aiming at the whole worm Chinese medicinal material, remove rheumatism, and patients need to pay attention to the medicine, can cause toxic and side effects after long-term administration, can improve the muscle strength of the medicine, accelerate the repair of damaged nerve tissues, and improve the transmission and metabolic disorders of the nerve tissues.

Description

Medicine for recovering normal conduction function of nerves and preparation method thereof
Technical Field
The invention relates to the technical field of medicines, in particular to a medicine for recovering normal conduction function of nerves and a preparation method thereof.
Background
The medicine is used for preventing, treating and diagnosing human diseases, purposefully regulating the physiological function of human and prescribing substances with indications or functional indications, usage and dosage, and comprises traditional Chinese medicinal materials, traditional Chinese medicine decoction pieces, Chinese patent medicines, chemical bulk drugs and preparations thereof, antibiotics, biochemical medicines, radioactive medicines, serum, vaccines, blood products, diagnostic medicines and the like, nerve conduction, that is, the conduction process of nerve impulse is an electrochemical process, which is an electrochemical change that occurs sequentially on nerve fibers, and when a nerve is stimulated, the permeability of cell membrane is changed sharply, and experiments with isotope-labeled ions prove that when nerve fiber is stimulated (such as electrical stimulation), the influx of Na + was increased 20-fold compared to the unstimulated, while the efflux of K + was increased 9-fold, nerve impulses therefore occur with a large influx of Na + and a large efflux of K +.
The currently clinically used nerve injury drugs comprise exogenous neurotrophic factors, adenosine monophosphate cyclooxygenase activators, cyclic adenosine monophosphate, protein kinase C, inflammatory factors, vitamin B families and the like, the currently used drugs are used for treating damaged nerves, the irritation to the nerves is large, the drug effect can be sensed in a very short time, the nerves have certain feedback, but the drugs have certain side effects, and the adverse reactions such as chronic pain, abnormal nerve reflex and the like can be caused.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides a medicine for recovering the normal conduction function of nerves and a preparation method thereof, which solve the problem of adverse reactions such as chronic pain, abnormal nerve reflex and the like.
In order to achieve the purpose, the invention is realized by the following technical scheme: a medicine for restoring normal conduction function of nerves comprises the following raw materials in parts by weight: 5-10 parts of ligusticum wallichii, 5-10 parts of scutellaria baicalensis, 3-7 parts of nux vomica, 2-8 parts of gastrodia elata, 4-9 parts of angelica sinensis, 5-7 parts of lycopodium clavatum, 1-3 parts of rose, 5-10 parts of salvia miltiorrhiza, 6-11 parts of garden balsam stem, 2-6 parts of safflower, 7-9 parts of scorpion, 2-5 parts of nucleolus, 4-9 parts of astragalus membranaceus, 15-10 parts of vitamin B, 125-10 parts of vitamin B, 10-20 parts of ethanol, 6-12 parts of nerve growth factor, 4-9 parts of ganglioside, 3-7 parts of oryzanol, 3-7 parts of Naofukang and 2-6 parts of citicoline.
Preferably, the raw materials comprise the following components: 8 parts of ligusticum wallichii, 8 parts of scutellaria baicalensis, 5 parts of nux vomica, 5 parts of gastrodia elata, 7 parts of angelica sinensis, 6 parts of lycopodium clavatum, 2 parts of rose, 8 parts of salvia miltiorrhiza, 6 parts of garden balsam stem, 4 parts of safflower, 8 parts of scorpion, 3 parts of nucleolus, 6 parts of huangshi, 17 parts of vitamin B, 127 parts of vitamin B, 15 parts of ethanol, 9 parts of nerve growth factor, 7 parts of ganglioside, 5 parts of oryzanol, 5 parts of Naofukang and 4 parts of citicoline.
Preferably, the raw materials comprise the following components: 5 parts of ligusticum wallichii, 5 parts of scutellaria baicalensis, 3 parts of nux vomica, 2 parts of gastrodia elata, 4 parts of angelica sinensis, 5 parts of lycopodium clavatum, 1 part of rose, 5 parts of salvia miltiorrhiza, 6 parts of garden balsam stem, 2 parts of safflower, 7 parts of scorpion, 2 parts of nucleolus, 4 parts of huangshi, 15 parts of vitamin B, 125 parts of vitamin B, 10 parts of ethanol, 6 parts of nerve growth factor, 4 parts of ganglioside, 3 parts of oryzanol, 3 parts of Naofukang and 2 parts of citicoline.
Preferably, the raw materials comprise the following components: 10 parts of ligusticum wallichii, 10 parts of scutellaria baicalensis, 7 parts of nux vomica, 8 parts of gastrodia elata, 9 parts of angelica sinensis, 7 parts of lycopodium clavatum, 3 parts of rose, 10 parts of salvia miltiorrhiza, 11 parts of garden balsam stem, 6 parts of safflower, 9 parts of scorpion, 5 parts of nucleolus, 9 parts of radix astragali, 110 parts of vitamin B, 1210 parts of vitamin B, 20 parts of ethanol, 12 parts of nerve growth factor, 9 parts of ganglioside, 7 parts of oryzanol, 7 parts of Naofukang and 6 parts of citicoline.
Gangliosides are the main components of cerebroside carnosine and also the components of nerve cell membranes, promoting the regeneration and repair of damaged nerves.
Naofukang is a brain metabolism improving drug, has an improving effect on nerve injury caused by physical and chemical factors, and can enhance memory and improve learning ability.
The nerve growth factor has promoting effect on nerve broken end, and is beneficial to nerve recovery.
Citicoline is a commonly used drug for repairing nerve damage, and after a nerve damage disease occurs, the drug can be actively used for treatment.
The invention also discloses a preparation method of the medicine for recovering the normal conduction function of the nerves, which comprises the following steps:
s1, selecting a proper amount of ligusticum chuanxiong hort, radix scutellariae, semen strychni, rhizoma gastrodiae and angelica sinensis, pouring the ligusticum chuanxiong hort, radix scutellariae, semen strychni, rhizoma gastrodiae and angelica sinensis into clean water, cleaning, drying, pouring the dried medicinal materials into a pulverizer, pulverizing the medicinal materials, pouring the pulverized medicinal materials into boiling water, boiling the boiled medicinal materials in the boiling water for 30-50 minutes, pouring the boiled medicinal materials into a clean vessel, cooling to room temperature, precipitating during cooling, pouring the upper-layer liquid medicine out, and filtering to obtain a first mixture;
s2, selecting appropriate amounts of lycopodium clavatum, rose, salvia miltiorrhiza, garden balsam stem, safflower and scorpion, pouring the mixture into clean water, cleaning, drying, pouring the dried mixture into boiling water, boiling the mixture in the boiling water for 30-50 minutes, pouring appropriate amounts of nucleolus and astragalus membranaceus, continuing boiling for 10-20 minutes, pouring the mixture into a clean vessel, cooling to room temperature, precipitating during cooling, pouring out the liquid medicine on the upper layer, and filtering to obtain a second mixture;
s3, pouring the first mixture and the second mixture together, stirring, adding a proper amount of vitamin B1 and vitamin B12, stirring and mixing, controlling the stirring temperature at 50-80 ℃, stirring for 30-50 minutes, pouring a proper amount of nerve growth factor, ganglioside, oryzanol, Naokang and citicoline after uniformly mixing, continuously stirring for 1-2 hours, finally adding a proper amount of ethanol, uniformly mixing, pouring the mixture out, filtering, and sterilizing to obtain the medicine.
Preferably, in the S1, the medicinal material is crushed to obtain a 80-100 mesh sieve, so that the medicinal effect can be better exerted in the later period.
Preferably, in S3, the mixture is sterilized at 150-220 deg.C for 20-40 min.
Advantageous effects
The invention provides a medicine for recovering normal conduction function of nerves and a preparation method thereof. Compared with the prior art, the method has the following beneficial effects: the medicine for restoring the normal conduction function of the nerve and the preparation method thereof comprise the following raw materials in parts by weight: 5-10 parts of ligusticum wallichii, 5-10 parts of scutellaria baicalensis, 3-7 parts of nux vomica, 2-8 parts of gastrodia elata, 4-9 parts of angelica sinensis, 5-7 parts of lycopodium clavatum, 1-3 parts of rose, 5-10 parts of salvia miltiorrhiza, 6-11 parts of garden balsam stem, 2-6 parts of safflower, 7-9 parts of scorpion, 2-5 parts of nucleolus, 4-9 parts of astragalus mongholicus, 15-10 parts of vitamin B, 125-10 parts of vitamin B, 10-20 parts of ethanol, 6-12 parts of nerve growth factor, 4-9 parts of ganglioside, 3-7 parts of oryzanol, 3-7 parts of Naofukang and 2-6 parts of citicoline, and by the antithrombotic and antioxidant effects of the ligusticum wallichii, the nerve injury caused by ischemia can be treated, and the immunity of a patient can be improved by taking the ligusticum wallichii, has obvious actual effect on lumbar vertebra nerve compression damage, has rich and colorful nutrient elements in the scutellaria baicalensis, has the effect of maintaining nerves, reduces cholesterol, is beneficial to the growth and development of neuron cells, treats facial nerve damage well through nux vomica, has the effects of relieving swelling, stopping pain and dispelling wind, has the effects of promoting blood circulation, removing blood stasis and dredging collaterals, has the actual effect of relieving pain caused by neuritis and neuritis pain caused by poisoning, has the effect of maintaining heart, can be taken for a long time, has strong effect of inhibiting pathogenic bacteria through lycopodium clavatum, has the effects of promoting blood circulation, removing blood stasis, dispelling cold and relieving nerve injury caused by severe cold irritation, fully exerts the medicinal efficacy for 2 to 3 clocks after the garden balsam stem is taken, has the good effects of relieving pain, has the effects of promoting blood circulation, promoting digestion, is beneficial to a blood circulation system, and has the effects of soothing nerves, helping sleep, benefiting qi, invigorating blood circulation and dispelling blood stasis, can be used for treating sleep disorder caused by nerve injury, relieving whole body muscle stiffness caused by nerve injury, removing rheumatism, and improving muscle strength, accelerating repair of injured nerve tissue, and improving nerve tissue transmission and metabolism disorder.
Detailed Description
The following will clearly and completely describe the technical solutions in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention provides three technical schemes: a medicine for restoring normal conduction function of nerves comprises the following raw materials in parts by weight: 5-10 parts of ligusticum wallichii, 5-10 parts of scutellaria baicalensis, 3-7 parts of nux vomica, 2-8 parts of gastrodia elata, 4-9 parts of angelica sinensis, 5-7 parts of lycopodium clavatum, 1-3 parts of rose, 5-10 parts of salvia miltiorrhiza, 6-11 parts of garden balsam stem, 2-6 parts of safflower, 7-9 parts of scorpion, 2-5 parts of nucleolus, 4-9 parts of astragalus membranaceus, 15-10 parts of vitamin B, 125-10 parts of vitamin B, 10-20 parts of ethanol, 6-12 parts of nerve growth factor, 4-9 parts of ganglioside, 3-7 parts of oryzanol, 3-7 parts of Naofukang and 2-6 parts of citicoline.
The preparation method specifically comprises the following embodiments:
example one
S1, selecting 8 parts of ligusticum chuanxiong hort, 8 parts of radix scutellariae, 5 parts of semen strychni, 5 parts of rhizoma gastrodiae and 7 parts of angelica, pouring the ligusticum chuanxiong hort, 8 parts of radix scutellariae, 5 parts of semen strychni, 5 parts of rhizoma gastrodiae and 7 parts of angelica into clean water, cleaning, drying, pouring the dried medicinal materials into a pulverizer to pulverize the medicinal materials, pouring the pulverized medicinal materials into boiling water, boiling the boiled medicinal materials in the boiling water for 40 minutes, pouring the boiled medicinal materials into a clean container, cooling to room temperature, precipitating during the cooling process, pouring the upper-layer medicinal liquid out, and filtering to obtain a first mixture;
s2, selecting 6 parts of lycopodium clavatum, 2 parts of rose, 8 parts of salvia miltiorrhiza, 6 parts of garden balsam stem, 4 parts of safflower and 8 parts of scorpion, pouring the same into clean water for cleaning, then drying, pouring into boiling water, boiling the same in the boiling water for 40 minutes, then pouring 3 parts of nucleolus and 6 parts of astragalus, continuing boiling for 15 minutes, then pouring the same into a clean vessel for cooling to room temperature, and in the cooling process, optionally precipitating, pouring out the upper-layer liquid medicine, and then filtering to obtain a second mixture;
s3, pouring the first mixture and the second mixture together, stirring, adding 7 parts of vitamin B1 and 7 parts of vitamin B12, stirring and mixing, controlling the stirring temperature at 65 ℃, stirring for 40 minutes, pouring 9 parts of nerve growth factor, 7 parts of ganglioside, 5 parts of oryzanol, 5 parts of Naofukang and 4 parts of citicoline after uniformly mixing, continuing stirring for 1.5 hours, finally adding 15 parts of ethanol, pouring out the mixture after uniformly mixing, filtering, and sterilizing to obtain the medicine.
Example two
S1, selecting 5 parts of ligusticum chuanxiong hort, 5 parts of radix scutellariae, 3 parts of semen strychni, 2 parts of rhizoma gastrodiae and 4 parts of angelica, pouring the ligusticum chuanxiong hort, 5 parts of radix scutellariae, 3 parts of semen strychni, 2 parts of rhizoma gastrodiae and 4 parts of angelica into clean water, cleaning, drying, pouring the dried medicinal materials into a pulverizer, pulverizing, pouring the pulverized medicinal materials into boiling water, boiling the boiled medicinal materials in the boiling water for 30 minutes, pouring the boiled medicinal materials into a clean container, cooling to room temperature, precipitating during the cooling process, pouring the upper-layer medicinal liquid out, and filtering to obtain a first mixture;
s2, selecting 5 parts of lycopodium clavatum, 1 part of rose, 5 parts of salvia miltiorrhiza, 6 parts of garden balsam stem, 2 parts of safflower and 7 parts of scorpion, pouring the same into clean water for cleaning, then drying, pouring into boiling water, boiling the same in the boiling water for 30 minutes, then pouring 2 parts of nucleolus and 4 parts of astragalus, continuing boiling for 10 minutes, then pouring the same into a clean vessel for cooling to room temperature, and in the cooling process, optionally precipitating, pouring out the upper-layer liquid medicine, and then filtering to obtain a second mixture;
s3, pouring the first mixture and the second mixture together, stirring, adding 5 parts of vitamin B1 and 5 parts of vitamin B12, stirring and mixing, controlling the stirring temperature at 50 ℃, stirring for 30 minutes, pouring 6 parts of nerve growth factor, 4 parts of ganglioside, 3 parts of oryzanol, 3 parts of Naofukang and 2 parts of citicoline after uniformly mixing, continuing stirring for 1 hour, finally adding 10 parts of ethanol, pouring the mixture out, filtering, and sterilizing to obtain the medicine.
EXAMPLE III
S1, selecting 10 parts of ligusticum chuanxiong hort, 10 parts of radix scutellariae, 7 parts of semen strychni, 8 parts of rhizoma gastrodiae and 9 parts of angelica, pouring the ligusticum chuanxiong hort, 10 parts of radix scutellariae, 7 parts of semen strychni, 8 parts of rhizoma gastrodiae and 9 parts of angelica into clean water, cleaning, drying, pouring the dried medicinal materials into a pulverizer, pulverizing, pouring the pulverized medicinal materials into boiling water, boiling the boiled medicinal materials in the boiling water for 50 minutes, pouring the boiled medicinal materials into a clean container, cooling to room temperature, precipitating during the cooling process, pouring the upper-layer liquid medicine out, and filtering to obtain a first mixture;
s2, selecting 7 parts of lycopodium clavatum, 3 parts of rose, 10 parts of salvia miltiorrhiza, 11 parts of garden balsam stem, 6 parts of safflower and 9 parts of scorpion, pouring the eupatorium clavatum, the rose, the salvia miltiorrhiza, the garden balsam stem, the safflower and the 9 parts of scorpion into clean water, cleaning, drying, pouring into boiling water, boiling for 50 minutes in the boiling water, pouring 5 parts of nucleolus and 9 parts of astragalus, continuously boiling for 20 minutes, pouring the nucleolus and the astragalus into a clean vessel, cooling to room temperature, precipitating in the cooling process, pouring out the upper-layer liquid medicine, and filtering to obtain a second mixture;
s3, pouring the first mixture and the second mixture together, stirring, adding 10 parts of vitamin B1 and 10 parts of vitamin B12, stirring and mixing, controlling the stirring temperature at 80 ℃, stirring for 50 minutes, pouring 12 parts of nerve growth factor, 9 parts of ganglioside, 7 parts of oryzanol, 7 parts of Naofukang and 6 parts of citicoline after uniformly mixing, continuing stirring for 2 hours, finally adding 20 parts of ethanol, pouring out the mixture after uniformly mixing, filtering, and sterilizing to obtain the medicine.
And those not described in detail in this specification are well within the skill of those in the art.
Comparative experiment
Randomly selecting common nerve restoring medicines as a control group, respectively testing the pressure sensation, the pain sensation and the touch sensation of a patient after use under the conditions consistent with the above conditions, recording the result, operating at the same time and under the same conditions, and simultaneously counting data and making a statistical table chart in the detection process, wherein the statistical table chart is shown in the following table.
Group of Example one Example two EXAMPLE III Control group
Pressure sense (%) 98 99 95 85
Pain sense (%) 95 97 94 87
Touch (%) 93 95 95 80
As shown in the above table, the ligusticum wallichii has the effects of resisting thrombus, oxidation and coagulation, can treat nerve injury caused by ischemia, patients can improve immunity after taking the ligusticum wallichii, and has a remarkable practical effect on lumbar compression nerve injury, the radix scutellariae has rich and colorful nutrient elements inside, has a nerve maintenance effect, reduces cholesterol, is beneficial to the growth and development of neuron cells, semen strychni has good effects on treating facial nerve injury, and has the effects of relieving swelling, stopping pain and dispelling wind, the gastrodia elata has the effects of activating blood, dissolving stasis and dredging collaterals, has a remarkable pain relieving practical effect on neuritis and neuritis pain caused by poisoning, has a maintenance effect on heart, can be taken for a long time, has strong effect of inhibiting common clubmoss herb, has the effects of activating blood, dissolving stasis, dispelling wind and dispelling cold, can alleviate nerve injury caused by severe cold irritation, and the lopseed can fully exert the efficacy after taking 2 to 3 bells, the peach kernel has the effects of promoting blood circulation to remove blood stasis and promoting digestion, is beneficial to a blood circulation system, the salvia miltiorrhiza bunge has the effects of soothing nerves, helping sleep, tonifying qi, nourishing blood and promoting blood circulation to remove blood stasis, can treat sleep disorder caused by nerve injury, can relieve the whole body muscle stiffness caused by nerve injury and remove rheumatism aiming at scorpion traditional Chinese medicinal materials, and patients need to pay attention to the medicine, can cause toxic and side effects after long-term administration, can improve the muscle strength of the medicine, accelerate the repair of injured nerve tissues and improve the transmission and metabolic disorder of the nerve tissues.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (7)

1. A medicine for restoring normal conduction function of nerves is characterized in that: the raw materials comprise the following components in parts by weight: 5-10 parts of ligusticum wallichii, 5-10 parts of scutellaria baicalensis, 3-7 parts of nux vomica, 2-8 parts of gastrodia elata, 4-9 parts of angelica sinensis, 5-7 parts of lycopodium clavatum, 1-3 parts of rose, 5-10 parts of salvia miltiorrhiza, 6-11 parts of garden balsam stem, 2-6 parts of safflower, 7-9 parts of scorpion, 2-5 parts of nucleolus, 4-9 parts of astragalus membranaceus, 15-10 parts of vitamin B, 125-10 parts of vitamin B, 10-20 parts of ethanol, 6-12 parts of nerve growth factor, 4-9 parts of ganglioside, 3-7 parts of oryzanol, 3-7 parts of Naofukang and 2-6 parts of citicoline.
2. The medicament for restoring the normal conduction function of nerves as claimed in claim 1, wherein: the raw materials comprise the following components: 8 parts of ligusticum wallichii, 8 parts of scutellaria baicalensis, 5 parts of nux vomica, 5 parts of gastrodia elata, 7 parts of angelica sinensis, 6 parts of lycopodium clavatum, 2 parts of rose, 8 parts of salvia miltiorrhiza, 6 parts of garden balsam stem, 4 parts of safflower, 8 parts of scorpion, 3 parts of nucleolus, 6 parts of huangshi, 17 parts of vitamin B, 127 parts of vitamin B, 15 parts of ethanol, 9 parts of nerve growth factor, 7 parts of ganglioside, 5 parts of oryzanol, 5 parts of Naofukang and 4 parts of citicoline.
3. The medicament for restoring the normal conduction function of nerves as claimed in claim 1, wherein: the raw materials comprise the following components: 5 parts of ligusticum wallichii, 5 parts of scutellaria baicalensis, 3 parts of nux vomica, 2 parts of gastrodia elata, 4 parts of angelica sinensis, 5 parts of lycopodium clavatum, 1 part of rose, 5 parts of salvia miltiorrhiza, 6 parts of garden balsam stem, 2 parts of safflower, 7 parts of scorpion, 2 parts of nucleolus, 4 parts of huangshi, 15 parts of vitamin B, 125 parts of vitamin B, 10 parts of ethanol, 6 parts of nerve growth factor, 4 parts of ganglioside, 3 parts of oryzanol, 3 parts of Naofukang and 2 parts of citicoline.
4. The medicament for restoring the normal conduction function of nerves as claimed in claim 1, wherein: the raw materials comprise the following components: 10 parts of ligusticum wallichii, 10 parts of scutellaria baicalensis, 7 parts of nux vomica, 8 parts of gastrodia elata, 9 parts of angelica sinensis, 7 parts of lycopodium clavatum, 3 parts of rose, 10 parts of salvia miltiorrhiza, 11 parts of garden balsam stem, 6 parts of safflower, 9 parts of scorpion, 5 parts of nucleolus, 9 parts of radix astragali, 110 parts of vitamin B, 1210 parts of vitamin B, 20 parts of ethanol, 12 parts of nerve growth factor, 9 parts of ganglioside, 7 parts of oryzanol, 7 parts of Naofukang and 6 parts of citicoline.
5. A preparation method of a medicine for recovering normal conduction function of nerves is characterized in that: the method specifically comprises the following steps:
s1, selecting a proper amount of ligusticum chuanxiong hort, radix scutellariae, semen strychni, rhizoma gastrodiae and angelica sinensis, pouring the ligusticum chuanxiong hort, radix scutellariae, semen strychni, rhizoma gastrodiae and angelica sinensis into clean water, cleaning, drying, pouring the dried medicinal materials into a pulverizer, pulverizing the medicinal materials, pouring the pulverized medicinal materials into boiling water, boiling the boiled medicinal materials in the boiling water for 30-50 minutes, pouring the boiled medicinal materials into a clean vessel, cooling to room temperature, precipitating during cooling, pouring the upper-layer liquid medicine out, and filtering to obtain a first mixture;
s2, selecting appropriate amounts of lycopodium clavatum, rose, salvia miltiorrhiza, garden balsam stem, safflower and scorpion, pouring the mixture into clean water, cleaning, drying, pouring the dried mixture into boiling water, boiling the mixture in the boiling water for 30-50 minutes, pouring appropriate amounts of nucleolus and astragalus membranaceus, continuing boiling for 10-20 minutes, pouring the mixture into a clean vessel, cooling to room temperature, precipitating during cooling, pouring out the liquid medicine on the upper layer, and filtering to obtain a second mixture;
s3, pouring the first mixture and the second mixture together, stirring, adding a proper amount of vitamin B1 and vitamin B12, stirring and mixing, controlling the stirring temperature at 50-80 ℃, stirring for 30-50 minutes, pouring a proper amount of nerve growth factor, ganglioside, oryzanol, Naokang and citicoline after uniformly mixing, continuously stirring for 1-2 hours, finally adding a proper amount of ethanol, uniformly mixing, pouring the mixture out, filtering, and sterilizing to obtain the medicine.
6. The method for preparing a medicament for restoring normal conduction function of nerves according to claim 5, wherein: in the S1, the medicinal materials are crushed to obtain 80-100 mesh sieve, so that the medicinal effect can be better exerted in the later period.
7. The method for preparing a medicament for restoring normal conduction function of nerves according to claim 5, wherein: in the S3, the sterilization temperature of the mixture is 150-220 ℃, and the sterilization time is 20-40 minutes.
CN202111067303.1A 2021-09-13 2021-09-13 Medicine for recovering normal conduction function of nerves and preparation method thereof Pending CN113648403A (en)

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