CN113616692A - Dingtengyantong mixture and preparation method thereof - Google Patents

Dingtengyantong mixture and preparation method thereof Download PDF

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Publication number
CN113616692A
CN113616692A CN202010530200.3A CN202010530200A CN113616692A CN 113616692 A CN113616692 A CN 113616692A CN 202010530200 A CN202010530200 A CN 202010530200A CN 113616692 A CN113616692 A CN 113616692A
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Prior art keywords
mixture
asarum
clove
filtering
squeezed liquid
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CN202010530200.3A
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Chinese (zh)
Inventor
肖军宏
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Guangzhou Hongkang Pharmaceutical Technology Co ltd
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Guangzhou Hongkang Pharmaceutical Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/31Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Insects & Arthropods (AREA)
  • Animal Husbandry (AREA)
  • Otolaryngology (AREA)
  • Zoology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a Dingteng toothache mixture and a preparation method thereof, wherein the Dingteng toothache mixture comprises the following components in percentage by mass: clove leaves: 1% -40% of asarum: 1% -30% and nutgall: 1-20%, and the preparation method of the mixture for treating toothache comprises the following steps: cleaning herba asari, folium Caryophylli and Galla Turcica with clear water, freezing, and cold pressing to obtain squeezed solution; storing the squeezed liquid obtained in the step S1 at constant temperature, filtering the squeezed liquid through a filter screen, squeezing and filtering the filtered filter residue through a fiber filter screen again, repeatedly operating for 3-6 times, and standing; the invention has the beneficial effects that: the prescription is added with nutgall and gallnut which are used for a vitamin prescription on the basis of clove and asarum which are traditional Chinese medicine prescriptions, wherein the gallic acid has the functions of antibiosis and sedation, and the gallotannin has the functions of inducing astringency, stopping bleeding, diminishing inflammation and the like.

Description

Dingtengyantong mixture and preparation method thereof
Technical Field
The invention relates to the technical field of toothache mixtures, in particular to a tooth pain mixture and a preparation method thereof.
Background
Modern people have fast pace of life and unhealthy diet, which easily causes gum and oral diseases, mouth and tongue sores, swollen and sore throat, smelly mouth and smoke, etc., the traditional Chinese medicine formula only contains clove and asarum, so that the traditional Chinese medicine formula lacks the effects of antibiosis, sedation, astringency, hemostasis, inflammation diminishing and the like.
In addition, most of the medicines for treating the symptoms in the market are capsule type oral medicines, and the problems of slow absorption and poor curative effect of a human body are easy to appear.
Disclosure of Invention
The invention aims to provide a tooth pain mixture and a preparation method thereof, and aims to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme that the tooth pain mixture comprises the following components in percentage by mass: clove leaves: 1% -40% of asarum: 1% -30% and nutgall: 1 to 20 percent.
Preferably, the ratio of herba asari to Galla Turcica is 2: 1.
Preferably, the preparation method of the toothache mixture comprises the following steps:
s1, washing the asarum, the clove leaves and the gallnut with clear water, freezing, and then cold-pressing to obtain a squeezed liquid;
s2, storing the squeezed liquid obtained in the S1 at constant temperature, filtering the squeezed liquid through a filter screen, squeezing and filtering the filtered filter residue through a fiber filter screen again, repeatedly operating for 3-6 times, and standing;
s3, removing precipitates of the clove leaves, the gallnuts and the squeezed liquid of the asarum which are subjected to standing at S2;
s4, removing precipitates, and mixing the distilled water with the clove leaves, the gallnut and the asarum according to the total proportion: 1: 1, adding distilled water and uniformly stirring;
s5, measuring the concentration of the clove leaf, nutgall and asarum squeezing liquid in the mixture obtained in S4, and producing and packaging after the mixture is qualified.
Preferably, in step S2, the first filtering is performed by using a mesh made of aluminum alloy for the first time, and the subsequent screening is performed by extrusion filtering through a soft fiber mesh.
Preferably, the sediment is removed in step S3 by vacuum-pumping the pressing liquid from the top of the sediment in the container, and collecting the part with the pressing liquid from the bottom, and extracting after accumulating a certain volume.
Preferably, in the step S4, the stirring is started when the distilled water is added, and the stirring is continued for 3 to 5min after the addition is completed to make the mixture completely uniform.
Preferably, the clove leaves, the nutgall and the asarum are all native plants, and the dehydrated raw materials cannot be used.
Compared with the prior art, the invention has the beneficial effects that: the prescription is added with nutgall and gallnut which are used for a vitamin prescription on the basis of clove and asarum which are traditional Chinese medicine prescriptions, wherein the gallic acid has the functions of antibiosis and sedation, and the gallotannin has the functions of inducing astringency, stopping bleeding, diminishing inflammation and the like.
Detailed Description
The invention provides a technical scheme that: the fine dental pain mixture comprises the following components in percentage by mass: clove leaves: 1% -40% of asarum: 1% -30% and nutgall: 1 to 20 percent.
Wherein the ratio of herba asari to Galla Turcica is 2: 1.
The preparation method of the Dingtengtongtong mixture comprises the following steps:
s1, washing the asarum, the clove leaves and the gallnut with clear water, freezing, and then cold-pressing to obtain a squeezed liquid;
s2, storing the squeezed liquid obtained in the S1 at constant temperature, filtering the squeezed liquid through a filter screen, squeezing and filtering the filtered filter residue through a fiber filter screen again, repeatedly operating for 3-6 times, and standing;
s3, removing precipitates of the clove leaves, the gallnuts and the squeezed liquid of the asarum which are subjected to standing at S2;
s4, removing precipitates, and mixing the distilled water with the clove leaves, the gallnut and the asarum according to the total proportion: 1: 1, adding distilled water and uniformly stirring;
s5, measuring the concentration of the clove leaf, nutgall and asarum squeezing liquid in the mixture obtained in S4, and producing and packaging after the mixture is qualified.
Wherein, in step S2, the aluminum alloy screen is used for the first time for the first filtration, and the subsequent screening is carried out the extrusion filtration by the fiber soft screen.
In step S3, the pressing liquid at the top of the sediment in the container is extracted by vacuum, and the part with the pressing liquid at the bottom is collected and extracted after a certain volume is accumulated.
In step S4, stirring is started when distilled water is added, and stirring is carried out for 3-5min after the addition is finished to ensure that the distilled water is completely uniform.
Wherein, the clove leaves, the gallnuts and the asarum are all native plants, and dehydrated raw materials cannot be used.
Example 1, a dental pain mixture, which comprises the following components in percentage by mass: clove leaves: 30% and asarum: 30% and nutgall: 15 percent.
A preparation method of the Dingteng toothache mixture comprises the following steps:
s1, washing the asarum, the clove leaves and the gallnut with clear water, freezing, and then cold-pressing to obtain a squeezed liquid;
s2, storing the squeezed liquid obtained in the S1 at constant temperature, filtering the squeezed liquid through a filter screen, squeezing and filtering the filtered filter residue through a fiber filter screen again, repeatedly operating for 3-6 times, and standing;
s3, removing precipitates of the clove leaves, the gallnuts and the squeezed liquid of the asarum which are subjected to standing at S2;
s4, removing precipitates, and mixing the distilled water with the clove leaves, the gallnut and the asarum according to the total proportion: 1: 1, adding distilled water and uniformly stirring;
s5, measuring the concentration of the clove leaf, nutgall and asarum squeezing liquid in the mixture obtained in S4, and producing and packaging after the mixture is qualified.
Example 2, a dental pain mixture, which comprises the following components in percentage by mass: clove leaves: 20% and asarum: 20% and nutgall: 10 percent.
A preparation method of the Dingteng toothache mixture comprises the following steps:
s1, washing the asarum, the clove leaves and the gallnut with clear water, freezing, and then cold-pressing to obtain a squeezed liquid;
s2, storing the squeezed liquid obtained in the S1 at constant temperature, filtering the squeezed liquid through a filter screen, squeezing and filtering the filtered filter residue through a fiber filter screen again, repeatedly operating for 3-6 times, and standing;
s3, removing precipitates of the clove leaves, the gallnuts and the squeezed liquid of the asarum which are subjected to standing at S2;
s4, removing precipitates, and mixing the distilled water with the clove leaves, the gallnut and the asarum according to the total proportion: 1: 1, adding distilled water and uniformly stirring;
s5, measuring the concentration of the clove leaf, nutgall and asarum squeezing liquid in the mixture obtained in S4, and producing and packaging after the mixture is qualified.

Claims (7)

1. The fine dental pain mixture is characterized by comprising the following components in percentage by mass: clove leaves: 1% -40% of asarum: 1% -30% and nutgall: 1 to 20 percent.
2. The dental pain mixture of claim 1, wherein: the ratio of folium Caryophylli, herba asari and Galla Turcica is 2: 1.
3. The dental pain mixture of claim 1, wherein: the preparation method of the Dingteng toothache mixture comprises the following steps:
s1, washing the asarum, the clove leaves and the gallnut with clear water, freezing, and then cold-pressing to obtain a squeezed liquid;
s2, storing the squeezed liquid obtained in the S1 at constant temperature, filtering the squeezed liquid through a filter screen, squeezing and filtering the filtered filter residue through a fiber filter screen again, repeatedly operating for 3-6 times, and standing;
s3, removing precipitates of the clove leaves, the gallnuts and the squeezed liquid of the asarum which are subjected to standing at S2;
s4, removing precipitates, and mixing the distilled water with the clove leaves, the gallnut and the asarum according to the total proportion: 1: 1, adding distilled water and uniformly stirring;
s5, measuring the concentration of the clove leaf, nutgall and asarum squeezing liquid in the mixture obtained in S4, and producing and packaging after the mixture is qualified.
4. The method for preparing a dental pain mixture according to claim 3, wherein the method comprises the following steps: in the step S2, the aluminum alloy screen is used for the first time for filtering, and the subsequent screening is performed by extruding and filtering through the fiber soft screen.
5. The method for preparing a dental pain mixture according to claim 3, wherein the method comprises the following steps: the sediment may be removed in step S3 by vacuum-pumping the squeezed liquid from the top of the sediment in the container, and collecting the part with the squeezed liquid from the bottom, and extracting after accumulating a certain volume.
6. The method for preparing a dental pain mixture according to claim 3, wherein the method comprises the following steps: in the step S4, stirring is started when distilled water is added, and stirring is carried out for 3-5min after the addition is finished so as to ensure that the distilled water is completely uniform.
7. The dental pain mixture of claim 1, wherein: the clove leaf, nutgall and asarum are all primary plants, and dehydrated raw materials cannot be used.
CN202010530200.3A 2020-06-11 2020-06-11 Dingtengyantong mixture and preparation method thereof Pending CN113616692A (en)

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CN202010530200.3A CN113616692A (en) 2020-06-11 2020-06-11 Dingtengyantong mixture and preparation method thereof

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114432361A (en) * 2022-01-11 2022-05-06 广州宏康医药科技有限公司 Preparation related to tenuiodontalgia for treating oral diseases and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1943631A (en) * 2005-10-08 2007-04-11 周小明 A Chinese traditional medicinal composition for treating toothache and dental arthritis and its preparing method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1943631A (en) * 2005-10-08 2007-04-11 周小明 A Chinese traditional medicinal composition for treating toothache and dental arthritis and its preparing method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114432361A (en) * 2022-01-11 2022-05-06 广州宏康医药科技有限公司 Preparation related to tenuiodontalgia for treating oral diseases and preparation method thereof

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Application publication date: 20211109