CN113599326A - 一种纯露抗老化面霜膏胶乳液的制备 - Google Patents
一种纯露抗老化面霜膏胶乳液的制备 Download PDFInfo
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- palmitoyl
- pure dew
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- 239000006071 cream Substances 0.000 title claims abstract description 13
- 239000004816 latex Substances 0.000 title claims abstract description 13
- 229920000126 latex Polymers 0.000 title claims abstract description 13
- 230000003712 anti-aging effect Effects 0.000 title claims abstract description 12
- 238000002360 preparation method Methods 0.000 title claims abstract description 8
- 239000002904 solvent Substances 0.000 claims abstract description 12
- SSISHJJTAXXQAX-ZETCQYMHSA-N L-ergothioneine Chemical compound C[N+](C)(C)[C@H](C([O-])=O)CC1=CNC(=S)N1 SSISHJJTAXXQAX-ZETCQYMHSA-N 0.000 claims abstract description 8
- 229940124277 aminobutyric acid Drugs 0.000 claims abstract description 8
- 229940093497 ergothioneine Drugs 0.000 claims abstract description 8
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 claims abstract description 8
- WSGCRSMLXFHGRM-DEVHWETNSA-N (2s)-2-[[(2s)-6-amino-2-[[(2s,3r)-2-[[(2s,3r)-2-[[(2s)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]hexanoyl]amino]-3-hydroxypropanoic acid Chemical compound CCCCCCCCCCCCCCCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(O)=O WSGCRSMLXFHGRM-DEVHWETNSA-N 0.000 claims abstract description 7
- LODWEXDBRZBADB-XEVVZDEMSA-N (2s)-6-amino-2-[[(2s)-2-[[(2s)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-methylbutanoyl]amino]hexanoic acid Chemical compound CCCCCCCCCCCCCCCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(O)=O LODWEXDBRZBADB-XEVVZDEMSA-N 0.000 claims abstract description 7
- 239000004863 Frankincense Substances 0.000 claims abstract description 7
- 229940094912 palmitoyl tripeptide-5 Drugs 0.000 claims abstract description 7
- 241000208340 Araliaceae Species 0.000 claims abstract description 6
- 235000003717 Boswellia sacra Nutrition 0.000 claims abstract description 6
- 235000012035 Boswellia serrata Nutrition 0.000 claims abstract description 6
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 6
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 6
- 241000220317 Rosa Species 0.000 claims abstract description 6
- 241001529742 Rosmarinus Species 0.000 claims abstract description 6
- 235000008434 ginseng Nutrition 0.000 claims abstract description 6
- 102100035140 Vitronectin Human genes 0.000 claims abstract description 4
- 108010031318 Vitronectin Proteins 0.000 claims abstract description 4
- 239000004615 ingredient Substances 0.000 claims abstract description 4
- 239000004094 surface-active agent Substances 0.000 claims abstract description 4
- 239000002537 cosmetic Substances 0.000 claims abstract description 3
- 240000007551 Boswellia serrata Species 0.000 claims abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 239000005740 Boscalid Substances 0.000 claims 2
- WYEMLYFITZORAB-UHFFFAOYSA-N boscalid Chemical compound C1=CC(Cl)=CC=C1C1=CC=CC=C1NC(=O)C1=CC=CN=C1Cl WYEMLYFITZORAB-UHFFFAOYSA-N 0.000 claims 2
- 229940118790 boscalid Drugs 0.000 claims 2
- 239000000839 emulsion Substances 0.000 claims 2
- QRYRORQUOLYVBU-VBKZILBWSA-N Carnosic acid Natural products CC([C@@H]1CC2)(C)CCC[C@]1(C(O)=O)C1=C2C=C(C(C)C)C(O)=C1O QRYRORQUOLYVBU-VBKZILBWSA-N 0.000 claims 1
- 108010087806 Carnosine Proteins 0.000 claims 1
- CQOVPNPJLQNMDC-UHFFFAOYSA-N N-beta-alanyl-L-histidine Natural products NCCC(=O)NC(C(O)=O)CC1=CN=CN1 CQOVPNPJLQNMDC-UHFFFAOYSA-N 0.000 claims 1
- 229940044199 carnosine Drugs 0.000 claims 1
- CQOVPNPJLQNMDC-ZETCQYMHSA-N carnosine Chemical compound [NH3+]CCC(=O)N[C@H](C([O-])=O)CC1=CNC=N1 CQOVPNPJLQNMDC-ZETCQYMHSA-N 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 description 12
- 239000000047 product Substances 0.000 description 5
- 241000717739 Boswellia sacra Species 0.000 description 4
- 238000001816 cooling Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 230000000474 nursing effect Effects 0.000 description 3
- 238000005303 weighing Methods 0.000 description 3
- 230000037303 wrinkles Effects 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 2
- 125000001312 palmitoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- 230000037339 smooth wrinkles Effects 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 229920002385 Sodium hyaluronate Polymers 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 229960001631 carbomer Drugs 0.000 description 1
- 229940082500 cetostearyl alcohol Drugs 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 description 1
- 229940119170 jojoba wax Drugs 0.000 description 1
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 1
- 239000005445 natural material Substances 0.000 description 1
- FBUKVWPVBMHYJY-UHFFFAOYSA-N nonanoic acid Chemical compound CCCCCCCCC(O)=O FBUKVWPVBMHYJY-UHFFFAOYSA-N 0.000 description 1
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 229940010747 sodium hyaluronate Drugs 0.000 description 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 description 1
- OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Cosmetics (AREA)
Abstract
本发明涉及化妆品领域，一种纯露抗老化面霜膏胶乳液的制备，其特征是以乳香纯露、玫瑰纯露、迷迭香纯露、人参花纯露的一种或者多种为溶剂，组合玻色因、氨基丁酸、麦角硫因、棕榈酰五肽‑3、棕榈酰三肽‑5，再添加油溶性成份、表面活性剂、增溶剂，制备成一种抗老化面霜膏胶乳液产品，其产品具有优良抗老化护理面部皮肤的作用，满足人们对面部护理的需要。
Description
技术领域
本发明涉及化妆品领域，一种纯露抗老化面霜膏胶乳液的制备，其特征是以乳香纯露、玫瑰纯露、迷迭香纯露、人参花纯露的一种或者多种为溶剂，组合玻色因、氨基丁酸、麦角硫因、棕榈酰五肽-3、棕榈酰三肽-5，再添加油溶性成份、表面活性剂、增溶剂，制备成一种抗老化面霜膏胶乳液产品，其产品具有优良抗老化护皮肤的作用，满足人们对面部护理的需要。
背景技术
现市场上销售的面部护理抗老化霜膏胶乳液，其护理功效仍欠缺，人们急需一种安全高品质的面部护理霜膏胶乳液，满足人们日常护理作用需要。
发明内容
本发明的目的是为了生产高品质面霜膏胶乳液，提出以乳香纯露、玫瑰纯露、迷迭香纯露、人参花纯露的一种或者多种为溶剂，组合玻色因、氨基丁酸、麦角硫因、棕榈酰五肽-3、棕榈酰三肽-5，再添加油溶性成份、表面活性剂、增溶剂，制备成一种抗老化面霜膏胶乳液产品，其产品具有优良抗老化护皮作用，纯露和化学产品协同作用，可帮助老化皮肤恢复弹性、嫩化皮肤、减缓皱纹的产生，保持皮肤湿润，能很好地满足人们护理的需要。
乳香纯露、玫瑰纯露、迷迭香纯露、人参花纯露含有许多芳香天然物质，对皮肤有很好护理作用，可使老化皮肤重生、恢复弹性、嫩化皮肤、抚平皱纹、减缓皱纹的产生，是很好护理皮肤的物质。纯露的使用是全部纯露的各种重量排列组合。
玻色因、氨基丁酸、麦角硫因、棕榈酰五肽-3、棕榈酰三肽-5具有抗氧化、抗老化，可使老化皮肤重生、恢复弹性、嫩化皮肤、抚平皱纹、减缓皱纹的产生，是很好护理皮肤的物质。
这些纯露和以上功能性物质，相互组合，协同发挥倍增效果，其护肤优于单个物质的使用。
它们组合使用可采用任意重量比例和任意排列组合。
在制备过程中，溶剂采用全部纯露，或采用纯露和水物质任意重量组合为溶剂。
实例1 纯露霜的制备
称取以下物质为A相：
辛酸葵酸三甘油酯 5g
单甘脂 1g
鲸蜡硬脂醇 3g
霍霍巴油 2g
棕榈酸异丙酯 5g
将以上A相中各组分加入容器A中，加热至90~100度，保温15分钟，降温至75度。
称取以下物质为B相：
丙二醇 15g
玻色因 1g
氨基丁酸 1g
麦角硫因 1g
甘油 4g
卡波900 0.2g
透明质酸钠 0.01g
乳香纯露 120g
EDTA--钠 0.01g
将以上B相中各组分加入容器B中，加热至90-100度，保温15分钟，搅拌均匀，降温至75度
将A容器物质加入B相容器中，均质5分钟，降温到40度。
称取以下物质为C相：
棕榈酰五肽-3 0.01g
棕榈酰三肽-5 0.01g
将C相物质加入到AB合并相中，均质5分钟，最后加入尼泊金0.1g,继续搅拌，冷却至室温，分装包装成为成品，即可。
Claims (6)
1.一种抗老化纯露面霜膏胶乳液化妆品的制备，其特征是以乳香纯露、玫瑰纯露、迷迭香纯露、人参花纯露的一种或者多种为溶剂，组合玻色因、氨基丁酸、麦角硫因、棕榈酰五肽-3、棕榈酰三肽-5，再添加油溶性成份、表面活性剂、增溶剂，制备成一种抗老化面霜膏胶乳液产品，其产品具有优良抗老化护皮肤的作用，满足人们对面部护理的需要。
2.根据权利要求1，纯露的使用指乳香纯露、玫瑰纯露、迷迭香纯露、人参花纯露的一种或者多种重量排列组合。
3.根据权利要求1，脱羧肌肽是玻色因、氨基丁酸、麦角硫因、棕榈酰五肽-3、棕榈酰三肽-5，由生物方法或者化学合成制备的产品。
4.根据权利要求1，纯露和玻色因、氨基丁酸、麦角硫因、棕榈酰五肽-3、棕榈酰三肽-5的组合，使用采用任意重量比例和任意排列组合。
5.根据权利要求1，在制备过程中，溶剂采用全部纯露。
6.根据权利要求1，在制备过程中，溶剂采用纯露和水的任意比例组合。
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