CN113575780A - Feed additive for preventing and treating calculus of cattle and sheep in fattening period and preparation method thereof - Google Patents

Feed additive for preventing and treating calculus of cattle and sheep in fattening period and preparation method thereof Download PDF

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CN113575780A
CN113575780A CN202110891259.XA CN202110891259A CN113575780A CN 113575780 A CN113575780 A CN 113575780A CN 202110891259 A CN202110891259 A CN 202110891259A CN 113575780 A CN113575780 A CN 113575780A
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sheep
cattle
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feed additive
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谢妮
马小林
何泰
王惠
王治维
张洋
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Xi'an Institute Of Foruminant
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/10Feeding-stuffs specially adapted for particular animals for ruminants
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/105Aliphatic or alicyclic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/189Enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/22Compounds of alkali metals

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Abstract

The invention discloses a feed additive for preventing and treating calculus of cattle and sheep in a fattening period, which comprises the following raw materials: natrii sulfas, bile acid, neutral protease, active dry yeast, herba Taraxaci, Alismatis rhizoma, semen plantaginis, herba Lysimachiae Christinae, herba Agastaches, rhizoma Atractylodis, radix astragali, radix Codonopsis and Glycyrrhrizae radix; the preparation method comprises the following steps: (1) weighing the raw materials; (2) oven drying herba Taraxaci, Alismatis rhizoma, semen plantaginis, herba Lysimachiae Christinae, herba Agastaches, rhizoma Atractylodis, radix astragali, radix Codonopsis and Glycyrrhrizae radix respectively, pulverizing, sieving, and mixing; (3) adding Natrii sulfas, bile acid, neutral protease and active dry yeast, sieving, and mixing. The feed additive has good effect on preventing the calculus of the cattle and sheep urinary system in the fattening period, can improve the productivity and slaughter performance, is convenient to use, has no residue, is safe to environment, low in production cost and simple and convenient in production process, reduces the elimination rate and economic loss, and improves the culture benefit.

Description

Feed additive for preventing and treating calculus of cattle and sheep in fattening period and preparation method thereof
Technical Field
The invention relates to the technical field of feed additives, in particular to a feed additive for preventing and treating calculus of cattle and sheep in a fattening period and a preparation method thereof.
Background
For ruminants, with the gradual and large increase of high-protein grain high-precision materials in the fattening period, excessive protein and fat intake, incomplete digestion, exercise restriction, reduction of urination, urine concentration, increased urea generation, increased urine pH, increased precursor substances which are easy to form calculus, such as mucin, mucopolysaccharide, exfoliated epithelial cells and the like are increased, and the occurrence probability of urinary calculus is increased.
At present, the common prevention specially used for the common urinary calculus of the ruminants in the market is mainly to add ammonium chloride (0.5-1%) or antibiotics into daily ration, but the feed additive has various defects.
Wherein, the ammonium chloride can acidify urine and promote the dissolution and discharge of alkaline stones such as calcium carbonate and phosphate stones, but the urine is acidic during the lactation period of animals, and is gradually changed into alkaline along with the intake of the vegetal forage grass, and besides phosphate stones, the occurrence rate of acidic urate stones, oxalate stones and other stones is increased; the long-term use of ammonium chloride can cause the decrease of feed intake, influence growth and development, damage to skin, eyes and digestive tract, and cause acidosis when the addition amount is too high.
Urease can break down urea to alkalize urine, breaking the equilibrium homeostasis of urine, and the increase of inflammatory products is the core substance for urinary calculus formation. The antibiotic can reduce the urease activity of urine and reduce the generation of inflammatory products, but the addition of the antibiotic only has good effect on preventing infectious calculi, and the long-term use of the antibiotic can easily cause antibiotic residue, the generation of drug-resistant bacteria, environmental pollution and ecological stability damage.
The stone is taken out by adopting the ruminant bladder fistulization operation in foreign treatment, the effect is good, but the requirements of professional technology, nursing and cost required by the operation are higher, and the method is not suitable for popularization of cattle and sheep in the domestic fattening period.
In conclusion, urinary system stones of cattle and sheep in the fattening period are frequently generated at present, the elimination rate is increased, common prevention and treatment measures have the problems of poor effect, high cost, influence on productivity, complex production process, high cost and the like, the long-term use of common ammonium chloride for prevention can influence the rumen function and production performance, the preventive addition and use of antibiotics in feed and cultivation are limited, operations can only treat diseases which are not suitable for prevention, the cost is high, the specificity is strong, and the method is not suitable for being used and popularized in farmers.
Therefore, the problem to be solved by technical personnel in the field is how to develop a feed additive capable of effectively preventing and treating calculus in the urinary system of cattle and sheep in the fattening period.
Disclosure of Invention
In view of the above, the invention aims to provide the feed additive for preventing and treating calculus of cattle and sheep in the fattening period and the preparation method thereof, the feed additive has a good effect on preventing calculus of urinary systems of cattle and sheep in the fattening period, can improve the productivity and slaughter performance, is convenient to use, free of residues, safe in environment, low in production cost, simple and convenient in production process, and capable of reducing the elimination rate and economic loss and improving the breeding benefit.
In order to achieve the purpose, the invention adopts the following technical scheme:
a feed additive for preventing and treating calculus of cattle and sheep in a fattening period comprises the following raw materials in parts by weight: 80-120 parts of mirabilite, 80-120 parts of bile acid, 80-120 parts of neutral protease, 60-100 parts of active dry yeast, 1.5-2.5 parts of dandelion, 1.5-2.5 parts of rhizoma alismatis, 1.5-2.5 parts of plantain seed, 1.5-2.5 parts of desmodium, 1.5-2.5 parts of wrinkled gianthyssop herb, 1.5-2.5 parts of rhizoma atractylodis, 2.5-3.5 parts of astragalus root, 2.5-3.5 parts of codonopsis pilosula and 1.5-2.5 parts of liquorice;
preferably: 100 parts of mirabilite, 100 parts of bile acid, 100 parts of neutral protease, 80 parts of active dry yeast, 2 parts of dandelion, 2 parts of rhizoma alismatis, 2 parts of semen plantaginis, 2 parts of desmodium, 2 parts of agastache rugosus, 2 parts of rhizoma atractylodis, 3 parts of astragalus membranaceus, 3 parts of codonopsis pilosula and 2 parts of liquorice.
The feed additive disclosed by the invention is low in addition amount, can promote drinking water and saliva secretion, increase the urine output, reduce urine retention, promote digestion, absorption and utilization of nutrients such as protein and fat, promote urea discharge, reduce the occurrence rate and elimination rate of urinary system calculus, is free of antibiotic residue, is free of pollution to the environment, is simple in use method, and is convenient to popularize and use in farmers.
Wherein the Natrii sulfas is crystal refined from Natrii sulfas of sulfate mineral, and contains water-containing sodium sulfate (Na)2SO4·10H2O), has the effects of relaxing bowels with purgative, moistening dryness, softening hard masses, clearing away fire and relieving swelling; it is often used for treating excess heat accumulation, abdominal distention and pain, constipation, and intestinal abscess with swelling and pain.
Bile acid is an important component of bile, and a plurality of experts in animal medical science research the bile acid to enlarge the contact area between the emulsified fat and lipase in an animal body; regulating and controlling the activity of pancreatic lipase and lipoprotein esterase to improve the fat hydrolysis metabolism; can transport fat in intestinal tract and promote fat absorption. In addition, bile acid obviously reduces the catabolism of autologous fat by regulating the activity of hormone sensitive lipase. In conclusion, the bile acid can save energy raw materials, improve the energy utilization rate, improve the growth performance and slaughter performance, and is positive energy for saving resources.
The neutral protease is an endonuclease obtained by fermenting and extracting bacillus subtilis, and can be used for various protein hydrolysis treatments. Under certain temperature and pH value, the neutral protease can hydrolyze macromolecular protein into products such as amino acid and the like, so that the effective absorption and utilization of the protein are facilitated, and the hydrolysate has high AN%, high hydrolysis degree and good flavor.
The active dry yeast is a dry yeast product which is prepared by squeezing, drying and dehydrating specially cultured fresh yeast and still keeps strong fermentation capacity. Squeezing the yeast into thin strip or pellet, continuously drying with low humidity circulating air via fluidized bed to make final fermentation water content reach about 8%, and maintaining the fermentation capacity of the yeast, and has the advantages of low water content, rapid rehydration, long storage time, and convenient use. The dormant active dry yeast can be rapidly revived after entering the intestinal tracts of the livestock and the poultry, and then grows and breeds; the active dry yeast belongs to facultative anaerobe, metabolizes and consumes oxygen in a digestive tract, creates an anaerobic environment, inhibits the growth and the reproduction of harmful floras such as escherichia coli and salmonella, and promotes the reproduction of beneficial bacteria such as bifidobacterium and lactobacillus; the active dry yeast is metabolized to generate organic acid, the pH value of the gastrointestinal tract is reduced, and the digestibility of the feed can be improved; the active dry yeast has stronger protease, amylase and lipase activities and can promote the digestion and absorption of nutrients in the feed.
The herba Taraxaci is dried whole plant of Taraxacum officinale Kitag of Compositae, Taraxacum sinicum Kitag or plants of the same genus. Bitter, sweet and cold. Clearing away heat and toxic material, dispersing swelling and dissipating stagnation, inducing diuresis and treating stranguria. It is mainly used for furuncle, swelling and toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, pulmonary abscess, intestinal abscess, jaundice due to damp-heat pathogen, stranguria with heat and pain, etc.
Alismatis rhizoma is dried tuber of Alisma orientalis (Sam.) Juzep. Sweet and bland in flavor and cold in nature. It enters kidney and bladder meridians. Induce diuresis and drain dampness, purge heat, resolve turbidity and reduce blood fat. Can be used for treating dysuria, edema, abdominal distention, diarrhea, oliguria, phlegm retention, vertigo, pyretic stranguria, pain, and hyperlipidemia.
The semen plantaginis is dried mature seed of Plantago asiatica L or Plantagodepressa Willd. Sweet in flavor and cold in nature. It enters liver, kidney, lung and small intestine meridians. Clearing away heat, inducing diuresis, treating stranguria, eliminating dampness, relieving diarrhea, improving eyesight, and eliminating phlegm. Can be used for treating pyretic stranguria, pain, edema, swelling, summer-heat dampness, diarrhea, conjunctival congestion, swelling and pain, and cough due to phlegm-heat.
The herba Lysimachiae Christinae is dried whole plant of Hance of Lysimachia christinae Hance of Primulaceae. Has the effects of promoting diuresis, removing jaundice, promoting urination, treating stranguria, removing toxic substance and relieving swelling. It is commonly used for jaundice due to damp-heat pathogen, gallbladder distention and hypochondriac pain, stranguria with stone, heat stranguria, painful urination, carbuncle, furuncle, snake and insect bite.
Agastache rugosa is the aerial part of Pogostemmincablin (blanco) Benth, or Agastache rugosa Agastache Cheugosus (Fisch. etmey) O.Ktz. Pungent flavor and warm nature. It enters spleen, stomach and lung meridians. Resolve dampness and enliven the spleen, avoid dirty and harmonize the middle energizer, relieve summer-heat and release exterior. Can be used for treating syndrome of dampness obstruction of spleen and stomach, abdominal distention, early stage of damp-warm syndrome, emesis, diarrhea, summer-heat dampness, fever with aversion to cold, and chest and abdominal fullness.
The rhizoma Atractylodis is dried rhizome of Atractylodes lancea DC or Atractylodes chinensis Koidz of Compositae. Pungent and bitter with warm nature. It enters spleen, stomach and liver meridians. Dry dampness and invigorate spleen, dispel wind and cold, improve vision. Can be used for treating damp obstruction of middle warmer, abdominal distention, diarrhea, edema, tinea pedis, atrophic debility cramped, rheumatalgia, wind-cold type common cold, night blindness, dim eyesight, and astringency.
Radix astragali is root of Astragalus membranaceus bge of Leguminosae. The main functional indications are as follows: tonify qi, strengthen superficies, expel toxin, expel pus, induce diuresis, and promote granulation. Can be used for treating deficiency of vital energy, asthenia, chronic diarrhea, proctoptosis, spontaneous perspiration, edema, uterine prolapse, albuminuria due to chronic nephritis, diabetes, and unhealed wound.
The radix Codonopsis is dried root of radix Codonopsis, radix Codonopsis Lanceolatae or radix Codonopsis Pilosulae of Campanulaceae. Sweet in flavor and neutral in nature. Has effects in invigorating spleen, replenishing qi, quenching thirst, invigorating spleen, tonifying lung, nourishing blood, and promoting salivation. Can be used for treating deficiency of spleen-lung qi, anorexia, listlessness, cough, asthma, deficiency of qi and blood, sallow complexion, palpitation, short breath, thirst due to body fluid consumption, and internal heat.
The Glycyrrhrizae radix is dried root and rhizome of Glycyrrhiza uralensis Fisch, Glycyrrhiza inflata Bat, or Glycyrrhiza glabra L of Leguminosae. Has the effects of invigorating spleen and replenishing qi, clearing away heat and toxic materials, eliminating phlegm and stopping cough, relieving spasm and pain, and harmonizing the medicines. It is indicated for spleen and stomach deficiency, lassitude and hypodynamia, palpitation and shortness of breath, cough with profuse sputum, spasm and pain of abdomen and limbs, carbuncle and sore, and to relieve toxicity and strong action of drugs.
A preparation method of a feed additive for preventing and treating calculus of cattle and sheep in a fattening period comprises the following steps:
(1) weighing the raw materials in parts by weight of the feed additive for preventing and treating calculus of cattle and sheep in the fattening period;
(2) oven drying herba Taraxaci, Alismatis rhizoma, semen plantaginis, herba Lysimachiae Christinae, herba Agastaches, rhizoma Atractylodis, radix astragali, radix Codonopsis and Glycyrrhrizae radix respectively, pulverizing, sieving, and mixing to obtain mixed Chinese medicine;
(3) adding Natrii sulfas, bile acid, neutral protease and active dry yeast into the mixed traditional Chinese medicines, sieving, and mixing to obtain the feed additive for preventing and treating calculus of cattle and sheep in fattening period.
Further, in the step (2), the drying temperature is 60 ℃ and the drying time is 180 min.
The further technical scheme has the beneficial effects that the traditional Chinese medicinal materials can be stored for a long time through drying, and are dehydrated, the original components of the traditional Chinese medicinal materials are kept, and the medicinal characteristics of the traditional Chinese medicinal materials are kept.
Further, in the step (2), the mesh number of the sieved mesh is the mesh number.
The further technical scheme has the beneficial effects that the traditional Chinese medicine and other raw materials are favorably and fully mixed by crushing and sieving, so that the exertion of the drug effect is ensured.
Further, in the step (3), the mesh number of the sieved mesh is 80-100 meshes.
The beneficial effect of adopting the further technical scheme is that the impurities in the mixture can be removed through sieving, thereby ensuring the quality of the feed additive.
According to the technical scheme, compared with the prior art, the invention has the following beneficial effects:
the feed additive disclosed by the invention can reduce the incidence rate of common urinary system calculus of ruminants in a fattening period with a high occurrence rate, soften hardness and dissipate stagnation, dissolve and discharge calculus, induce diuresis to reduce edema, increase the water intake, dilute urine, increase the urine discharge, avoid urine retention, promote the absorption and metabolism of protein and fat, reduce the formation of calculus precursors, promote the discharge of urea, reduce the precipitation of calculus crystals and promote the dissolution and discharge of calculus, is simple in use method, and can effectively prevent the urinary calculus of cattle and sheep in the fattening period, thereby reducing the elimination rate of the fattening cattle and sheep, improving the slaughter rate and increasing the economic benefit.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The feed additive for preventing and treating cattle and sheep calculus in the fattening period comprises the following raw materials by weight: 100kg of mirabilite, 100kg of bile acid, 100kg of neutral protease, 80kg of active dry yeast, 2kg of dandelion, 2kg of rhizoma alismatis, 2kg of plantain seed, 2kg of desmodium, 2kg of agastache rugosus, 2kg of rhizoma atractylodis, 3kg of astragalus membranaceus, 3kg of codonopsis pilosula and 2kg of liquorice;
the preparation method of the feed additive for preventing and treating calculus of cattle and sheep in the fattening period comprises the following steps:
(1) weighing the raw materials according to the weight;
(2) oven drying herba Taraxaci, Alismatis rhizoma, semen plantaginis, herba Lysimachiae Christinae, herba Agastaches, rhizoma Atractylodis, radix astragali, radix Codonopsis and Glycyrrhrizae radix at 60 deg.C for 180min respectively, sieving with 80 mesh sieve, and mixing to obtain mixed Chinese medicine;
(3) adding Natrii sulfas, bile acid, neutral protease and active dry yeast into the mixed traditional Chinese medicines, sieving with 80 mesh sieve, and mixing to obtain the feed additive for preventing and treating calculus of cattle and sheep in fattening period.
Example 2
The feed additive for preventing and treating cattle and sheep calculus in the fattening period comprises the following raw materials by weight: 80kg of mirabilite, 80kg of bile acid, 80kg of neutral protease, 60kg of active dry yeast, 1.5kg of dandelion, 1.5kg of rhizoma alismatis, 1.5kg of plantain seed, 1.5kg of desmodium, 1.5kg of wrinkled gianthyssop herb, 1.5kg of rhizoma atractylodis, 2.5kg of astragalus, 2.5kg of codonopsis pilosula and 1.5kg of liquorice;
the preparation method of the feed additive for preventing and treating calculus of cattle and sheep in the fattening period comprises the following steps:
(1) weighing the raw materials according to the weight;
(2) oven drying herba Taraxaci, Alismatis rhizoma, semen plantaginis, herba Lysimachiae Christinae, herba Agastaches, rhizoma Atractylodis, radix astragali, radix Codonopsis and Glycyrrhrizae radix at 60 deg.C for 180min respectively, sieving with 80 mesh sieve, and mixing to obtain mixed Chinese medicine;
(3) adding Natrii sulfas, bile acid, neutral protease and active dry yeast into the mixed traditional Chinese medicines, sieving with 100 mesh sieve, and mixing to obtain the feed additive for preventing and treating calculus of cattle and sheep in fattening period.
Example 3
The feed additive for preventing and treating cattle and sheep calculus in the fattening period comprises the following raw materials by weight: 120kg of mirabilite, 120kg of bile acid, 120kg of neutral protease, 100kg of active dry yeast, 2.5kg of dandelion, 2.5kg of rhizoma alismatis, 2.5kg of plantain seed, 2.5kg of desmodium, 2.5kg of wrinkled gianthyssop herb, 2.5kg of rhizoma atractylodis, 3.5kg of astragalus, 3.5kg of codonopsis pilosula and 2.5kg of liquorice;
the preparation method of the feed additive for preventing and treating calculus of cattle and sheep in the fattening period comprises the following steps:
(1) weighing the raw materials according to the weight;
(2) oven drying herba Taraxaci, Alismatis rhizoma, semen plantaginis, herba Lysimachiae Christinae, herba Agastaches, rhizoma Atractylodis, radix astragali, radix Codonopsis and Glycyrrhrizae radix at 60 deg.C for 180min respectively, sieving with 100 mesh sieve, and mixing to obtain mixed Chinese medicine;
(3) adding Natrii sulfas, bile acid, neutral protease and active dry yeast into the mixed traditional Chinese medicines, sieving with 100 mesh sieve, and mixing to obtain the feed additive for preventing and treating calculus of cattle and sheep in fattening period.
Performance testing
The feed additive for preventing and treating cattle and sheep calculus in the fattening period prepared in the embodiment 1-3 is taken for feeding test, and the operation steps are as follows:
(1) 200 weaned rams (castrate) of 3 months of age with similar weight, age and health consistent with feeding conditions were selected and divided into 4 groups of 50 animals each. The groups 1 to 3 are test groups, and the additives prepared in the examples 1 to 3 are respectively added into basic daily ration (concentrate supplement) according to the mass of 2.5 per mill; the 4 groups were control groups, fed basal diet, and no other additions. Barn feeding and captive breeding, freely drinking water, feeding twice a day, respectively at 8: feeding at 00 and 17:00, and feeding with silage corn and hay at free. Immunization, insect repellent and disinfection were performed according to conventional procedures. The test is divided into a pre-feeding period of 10 days and a positive test period of 60 days.
(2) In the test process of the pilot stage, daily food intake is recorded, the health condition of sheep is observed, and the urinary calculus disease case is judged if the urinary difficulty such as urine, oliguria, urine dripping, hematuria and frequent urination posture with the limbs diverged. After the test is finished, the weight of the sheep at the end and the weight of the sheep carcass are recorded (5 optional animals in each group are taken as an average value), and white crystal precipitates of the bladder, the ureter and the kidney are found in slaughtering and are also judged as the cases of the urinary calculus.
(3) The test detection indexes comprise average daily gain, dressing percentage and urinary calculus incidence.
The test results are shown in tables 1 to 3.
TABLE 1 sheep weight gain test results
Figure BDA0003196167880000081
As can be seen from Table 1, the average daily gain of sheep can be significantly increased by adding the additives prepared in examples 1-3 in a mass of 2.5 ‰ during the fattening period. Wherein, the effect of the embodiment 1 is the best, the average daily gain is 320.0g, which is improved by 9.1 percent compared with the control group; after the addition of the additive of the embodiment 2 and the embodiment 3, the increase is respectively 6.3 percent and 8.5 percent compared with the control group.
TABLE 2 test sheep slaughter test results
Group of Number of tests (only) Weight before slaughtering (kg) Carcass weight (kg) Dressing percentage (%)
Test group 1 5 46.2 24.67 53.4
Test group 2 5 45.0 23.18 51.5
Test group 3 5 45.4 24.15 53.2
Control group 5 44.8 22.04 49.2
As can be seen from Table 2, the addition of the additives prepared in examples 1 to 3 in a mass of 2.5 per thousand in the fattening period can significantly improve the slaughtering rate of sheep. Wherein, the effect of the embodiment 1 is the best, the dressing percentage is 53.4 percent, and the dressing percentage is improved by 8.5 percent compared with that of a control group; the dressing percentage after the addition of example 2 and example 3 was increased by 4.7% and 8.1% respectively compared to the control group.
TABLE 3 test results of incidence of urinary calculus in sheep
Group of Number of tests (only) Number of onset of urinary calculus Urinary calculus incidence (%)
Test group 1 50 1 2
Test group 2 50 2 4
Test group 3 50 1 2
Control group 50 6 12
As can be seen from Table 3, the additive prepared in examples 1-3 was added in an amount of 2.5 ‰ during fattening period, and the incidence of urinary calculus in sheep was significantly reduced. Wherein, with the best effect of the embodiment 1 and the embodiment 3, the incidence rate of the urinary calculus is 2 percent and is reduced by 83.3 percent compared with the control group; the incidence of urinary stones after addition of example 2 decreased by 66.7% compared to the control group.
The tests prove that the additive prepared in the embodiment 1-3 can improve the average daily gain of fattening sheep, increase the carcass weight, improve the slaughter rate of sheep, optimize the slaughter performance and play a certain role in improving the meat quality; meanwhile, the health degree of sheep flocks is also obviously improved, the physique is enhanced, the incidence rate of urinary calculus of fattening sheep is obviously reduced, and especially the best effect is obtained by the embodiment 1.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (6)

1. The feed additive for preventing and treating calculus of cattle and sheep in the fattening period is characterized by comprising the following raw materials in parts by weight: 80-120 parts of mirabilite, 80-120 parts of bile acid, 80-120 parts of neutral protease, 60-100 parts of active dry yeast, 1.5-2.5 parts of dandelion, 1.5-2.5 parts of rhizoma alismatis, 1.5-2.5 parts of plantain seed, 1.5-2.5 parts of lysimachia christinae hance, 1.5-2.5 parts of wrinkled gianthyssop, 1.5-2.5 parts of rhizoma atractylodis, 2.5-3.5 parts of astragalus mongholicus, 2.5-3.5 parts of codonopsis pilosula and 1.5-2.5 parts of liquorice.
2. The feed additive for preventing and treating calculus of cattle and sheep in fattening period according to claim 1, is characterized by comprising the following raw materials in parts by weight: 100 parts of mirabilite, 100 parts of bile acid, 100 parts of neutral protease, 80 parts of active dry yeast, 2 parts of dandelion, 2 parts of rhizoma alismatis, 2 parts of semen plantaginis, 2 parts of desmodium, 2 parts of agastache rugosus, 2 parts of rhizoma atractylodis, 3 parts of astragalus membranaceus, 3 parts of codonopsis pilosula and 2 parts of liquorice.
3. A preparation method of a feed additive for preventing and treating calculus of cattle and sheep in a fattening period is characterized by comprising the following steps:
(1) weighing the raw materials in parts by weight of the feed additive for preventing and treating cattle and sheep calculus in the fattening period according to claim 1 or 2;
(2) oven drying herba Taraxaci, Alismatis rhizoma, semen plantaginis, herba Lysimachiae Christinae, herba Agastaches, rhizoma Atractylodis, radix astragali, radix Codonopsis and Glycyrrhrizae radix respectively, pulverizing, sieving, and mixing to obtain mixed Chinese medicine;
(3) adding mirabilite, bile acid, neutral protease and active dry yeast into the mixed traditional Chinese medicine, sieving and uniformly mixing to obtain the feed additive for preventing and treating calculus of cattle and sheep in the fattening period.
4. The preparation method of the feed additive for preventing and treating calculus of cattle and sheep in fattening period according to claim 3, wherein in the step (2), the drying temperature is 60 ℃ and the drying time is 180 min.
5. The preparation method of the feed additive for preventing and treating calculus of cattle and sheep in fattening period according to claim 3, wherein in the step (2), the mesh number of the sieved screen is 80-100 meshes.
6. The preparation method of the feed additive for preventing and treating calculus of cattle and sheep in fattening period according to claim 3, wherein in the step (3), the mesh number of the sieved screen is 80-100 meshes.
CN202110891259.XA 2021-08-04 2021-08-04 Feed additive for preventing and treating calculus of cattle and sheep in fattening period and preparation method thereof Pending CN113575780A (en)

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