CN113546143A - Pharmaceutical composition for treating chronic bronchitis asthma and preparation method thereof - Google Patents
Pharmaceutical composition for treating chronic bronchitis asthma and preparation method thereof Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A61K36/06—Fungi, e.g. yeasts
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Abstract
The invention provides a pharmaceutical composition for treating chronic bronchitis asthma and a preparation method thereof, wherein the pharmaceutical composition is prepared from the following raw materials in parts by weight: atractylodis rhizoma, radix Codonopsis, fructus forsythiae, bupleuri radix, Glycyrrhrizae radix, herba Ephedrae, radix aucklandiae, radix Asteris, rhizoma Cynanchi Stauntonii, Poria, radix Stemonae, flos Lonicerae, semen Armeniacae amarum preparata, radix Platycodi, exocarpium Citri rubrum, cortex Magnolia officinalis, radix Adenophorae, and herba Andrographitis. The invention has strong pertinence, can shorten the course of treatment, has obvious curative effect, has short taking course of treatment, shortest 1-2 months and longest 3 months, can be immediately stopped after treatment, has no dependence and toxic or side effect, avoids toxic or side effect caused by the traditional medicine, has good stability, no rebound and relapse after clinical cure by taking the liquid medicine, saves the medication cost, is beneficial to reducing family and social burden, and has higher social value in the aspects of health, economy and social medical guarantee.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a pharmaceutical composition for treating chronic bronchitis asthma and a preparation method thereof.
Background
Chronic bronchitis is chronic nonspecific inflammation of trachea, bronchial mucosa and surrounding tissues, cough and expectoration are clinically used as main symptoms, the disease lasts for 3 months every year and lasts for 2 years or more, asthma is a allergic disease, is characterized by airway hyperreactivity and is characterized by paroxysmal dyspnea, and can be completely relieved after some medicines are used, but patients with chronic bronchitis and asthma can be clinically suffered, namely the patients with the chronic bronchitis and the asthma have the characteristics of the chronic bronchitis and the symptoms and signs of the asthma.
Most of the existing medicines have slow effect, and a small part of the existing medicines have quick effect, but the existing medicines are all symptoms and root causes, the root cause of the existing medicines can not be cured, and the existing medicines have the problems of toxic and side effects and high medicine dependence.
Therefore, it is very important to design and manufacture a pharmaceutical composition for treating chronic bronchitis asthma and a preparation method thereof.
Disclosure of Invention
In order to solve the technical problems, the invention provides a pharmaceutical composition for treating chronic bronchitis asthma and a preparation method thereof, which aim to solve the problems that most of the existing medicines take effect slowly, and a small part of the existing medicines take effect quickly, but all the medicines are symptoms and root causes, the root cause of the diseases cannot be cured, and the toxic and side effects and drug dependence are large.
A pharmaceutical composition for treating chronic bronchitis asthma comprises the following raw materials in parts by weight: 15-25 parts of bighead atractylodes rhizome, 20-25 parts of codonopsis pilosula, 10-25 parts of weeping forsythia, 10-15 parts of radix bupleuri, 15-25 parts of liquorice, 20-25 parts of ephedra, 10-20 parts of elecampane, 15-25 parts of aster, 15-25 parts of cynanchum glaucescens, 15-25 parts of poria cocos, 20-25 parts of radix stemonae, 15-25 parts of honeysuckle, 15-25 parts of fried almond, 15-25 parts of platycodon grandiflorum, 15-25 parts of exocarpium citri rubrum, 10-15 parts of mangnolia officinalis, 10-15 parts of adenophora tetraphylla and 10-15 parts of common andrographis herb.
Further, the feed is prepared from the following raw materials in parts by weight: 15 parts of bighead atractylodes rhizome, 20 parts of codonopsis pilosula, 10 parts of weeping forsythia, 10 parts of radix bupleuri, 15 parts of liquorice, 20 parts of ephedra, 10 parts of elecampane, 15 parts of aster, 15 parts of cynanchum glaucescens, 15 parts of poria cocos, 20 parts of radix stemonae, 15 parts of honeysuckle, 15 parts of fried almond, 15 parts of platycodon grandiflorum, 15 parts of exocarpium citri rubrum, 10 parts of mangnolia officinalis, 10 parts of adenophora tetraphylla and 10 parts of common andrographis herb.
Further, the feed is prepared from the following raw materials in parts by weight: 25 parts of bighead atractylodes rhizome, 25 parts of codonopsis pilosula, 25 parts of weeping forsythia, 15 parts of radix bupleuri, 25 parts of liquorice, 25 parts of ephedra, 20 parts of elecampane, 25 parts of aster, 25 parts of cynanchum glaucescens, 25 parts of poria cocos, 25 parts of radix stemonae, 25 parts of honeysuckle, 25 parts of fried almond, 25 parts of platycodon grandiflorum, 25 parts of exocarpium citri rubrum, 15 parts of mangnolia officinalis, 15 parts of adenophora tetraphylla and 15 parts of common andrographis herb.
Further, the preparation method comprises the following steps:
s1: mixing all the raw materials, and soaking in cold water until the water submerges the medicinal materials by 5 cm;
s2: boiling the mixture obtained in the last step with strong fire, decocting with slow fire, and performing solid-liquid separation;
s3: taking out the liquid obtained by solid-liquid separation, and vacuum packaging in three equal parts for later use.
Further, in the step S1, cold water is soaked for 5-6 hours.
Further, the step S2 is carried out by decocting for 40 minutes with slow fire.
Compared with the prior art, the invention has the following beneficial effects:
1. the invention has strong pertinence, particularly has quick response to dozens of years of asthma, cough, asthma and phlegm, improves the overall treatment level of the asthma, maintains three treatment courses for patients with middle-stage cough, asthma, phlegm and chronic asthma (chronic asthma) to cure clinically, can shorten the treatment course for refractory asthma (chronic asthma), has obvious curative effect, and has short administration course, shortest 1-2 months and longest 3 months when being taken.
2. The traditional Chinese medicine can be immediately stopped after treatment, has no dependence and toxic or side effect, avoids toxic or side effect caused by the traditional medicine, has good stability, no relapse and relapse after clinical cure by taking the medicine liquid, saves the medicine cost, is favorable for reducing family and social burden, and has higher social value in the aspects of health and economy and social medical guarantee.
Detailed Description
The invention is further described below:
example 1:
a pharmaceutical composition for treating chronic bronchitis asthma comprises the following raw materials in parts by weight: 15-25 parts of bighead atractylodes rhizome, 20-25 parts of codonopsis pilosula, 10-25 parts of weeping forsythia, 10-15 parts of radix bupleuri, 15-25 parts of liquorice, 20-25 parts of ephedra, 10-20 parts of elecampane, 15-25 parts of aster, 15-25 parts of cynanchum glaucescens, 15-25 parts of poria cocos, 20-25 parts of radix stemonae, 15-25 parts of honeysuckle, 15-25 parts of fried almond, 15-25 parts of platycodon grandiflorum, 15-25 parts of exocarpium citri rubrum, 10-15 parts of mangnolia officinalis, 10-15 parts of adenophora tetraphylla and 10-15 parts of common andrographis herb.
The preparation method comprises the following steps:
s1: mixing all the raw materials, and soaking in cold water until the water submerges the medicinal materials by 5 cm;
s2: boiling the mixture obtained in the last step with strong fire, decocting with slow fire, and performing solid-liquid separation;
s3: taking out the liquid obtained by solid-liquid separation, and vacuum packaging in three equal parts for later use.
And in the step S1, soaking in cold water for 5-6 hours.
And step S2, decocting for 40 minutes by slow fire.
Example 2:
a pharmaceutical composition for treating chronic bronchitis asthma is prepared from the following raw materials in parts by weight: 15 parts of bighead atractylodes rhizome, 20 parts of codonopsis pilosula, 10 parts of weeping forsythia, 10 parts of radix bupleuri, 15 parts of liquorice, 20 parts of ephedra, 10 parts of elecampane, 15 parts of aster, 15 parts of cynanchum glaucescens, 15 parts of poria cocos, 20 parts of radix stemonae, 15 parts of honeysuckle, 15 parts of fried almond, 15 parts of platycodon grandiflorum, 15 parts of exocarpium citri rubrum, 10 parts of mangnolia officinalis, 10 parts of adenophora tetraphylla and 10 parts of common andrographis herb.
The preparation method comprises the following steps:
s1: mixing all the raw materials, and soaking in cold water until the water submerges the medicinal materials by 5 cm;
s2: boiling the mixture obtained in the last step with strong fire, decocting with slow fire, and performing solid-liquid separation;
s3: taking out the liquid obtained by solid-liquid separation, and vacuum packaging in three equal parts for later use.
And in the step S1, soaking in cold water for 5-6 hours.
And step S2, decocting for 40 minutes by slow fire.
Example 3:
a pharmaceutical composition for treating chronic bronchitis asthma is prepared from the following raw materials in parts by weight: 25 parts of bighead atractylodes rhizome, 25 parts of codonopsis pilosula, 25 parts of weeping forsythia, 15 parts of radix bupleuri, 25 parts of liquorice, 25 parts of ephedra, 20 parts of elecampane, 25 parts of aster, 25 parts of cynanchum glaucescens, 25 parts of poria cocos, 25 parts of radix stemonae, 25 parts of honeysuckle, 25 parts of fried almond, 25 parts of platycodon grandiflorum, 25 parts of exocarpium citri rubrum, 15 parts of mangnolia officinalis, 15 parts of adenophora tetraphylla and 15 parts of common andrographis herb.
The preparation method comprises the following steps:
s1: mixing all the raw materials, and soaking in cold water until the water submerges the medicinal materials by 5 cm;
s2: boiling the mixture obtained in the last step with strong fire, decocting with slow fire, and performing solid-liquid separation;
s3: taking out the liquid obtained by solid-liquid separation, and vacuum packaging in three equal parts for later use.
And in the step S1, soaking in cold water for 5-6 hours.
And step S2, decocting for 40 minutes by slow fire.
The method comprises the following steps: wheezing is the result of the disturbance of the qi and phlegm phase, dysfunction of the spleen in transport and transformation, water-dampness retention in the interior and accumulation of phlegm. Phlegm-dampness obstructing the qi flow, chronic asthma, lung-kidney deficiency, shortness of breath and shortness of breath, and speech weakness.
In the recipe, Ma Huang, Lian Qiao and chai Hu are pungent in flavor and warm in property and pungent in flavor and cool in property, they are combined for clearing heat from lung. Dangshen, largehead atractylodes rhizome, liquorice and costus root have the effects of tonifying qi, strengthening spleen and tonifying lung. Poria cocos, Poria, by means capable of both having the effects of promoting diuresis, strengthening the effects of promoting diuresis, invigorating spleen and removing dampness and spleen and tranquilizing mind. Radix cynanchi stauntonii, radix stemonae, platycodon grandiflorum, radix adenophorae, aster, almond, exocarpium citri rubrum for clearing away the lung-heat, relieving cough, reducing phlegm and relieving asthma. Honeysuckle flower, herba Andrographitis, flos Lonicerae, herba Andrographitis, flos Lonicerae, herba Andrographitis, and herba Andrographitis, with effects of clearing away heat and toxic materials, cooling blood, relieving swelling, and dispelling wind heat.
The clinical medical record part is as follows:
case one:
zheng somewhere, woman, age 35, complain: chronic bronchitis asthma;
the medical history: cough, asthma and phlegm, 6 years old, the multi-aspect treatment effect is not good;
treatment: the treatment by the method has one course of treatment, obvious effect, clinical cure after 4 courses of treatment, good feedback up to now and no side effect.
Case two:
wang somebody, woman, age 68, chief complaints: chronic asthma;
the medical history: the diagnosis in the hospital in the market, the chronic asthma, the chronic tracheitis, the cough, the asthma and the phlegm, 30 years, 10 years of loss of labor capacity, and the multi-party treatment effect is not good;
treatment: 2018.5, the curative effect is obvious after 2 courses of multi-part treatment, the patient can be cured clinically after 6 courses of treatment, the physical labor can be dried, the feeling is good till now, the body is hard, and the asthma symptom is avoided.
Case three:
lie somewhere, woman, age 59, chief complaints: diagnosed by provincial hospitals, chronic bronchitis and asthma;
the medical history: cough, asthma, phlegm, 30 years and winter cachexia, and the curative effect is not good through multi-part treatment;
treatment: the patient is diagnosed 10 months in 2017, asthma, pain, dull complexion, cough and asthma are treated by the traditional Chinese medicine preparation for 1 course of treatment, and the effect is good, and the patient is cured clinically and communicated with a telephone for 4 courses of treatment.
Case four:
certain of plum, male, age 75, chief complaints: bronchitis and asthma:
the medical history: cough, asthma and phlegm for 1 year, and bronchitis and asthma are diagnosed by the hospital of province and standup;
treatment: after treatment, the patient is basically cured in one course of treatment, and is clinically cured in 3 courses of treatment, and the patient has no asthma symptoms at present after telephone visit.
The technical solutions of the present invention or similar technical solutions designed by those skilled in the art based on the teachings of the technical solutions of the present invention are all within the scope of the present invention.
Claims (6)
1. A pharmaceutical composition for treating chronic bronchitis asthma, which is characterized in that: the feed is prepared from the following raw materials in parts by weight: 15-25 parts of bighead atractylodes rhizome, 20-25 parts of codonopsis pilosula, 10-25 parts of weeping forsythia, 10-15 parts of radix bupleuri, 15-25 parts of liquorice, 20-25 parts of ephedra, 10-20 parts of elecampane, 15-25 parts of aster, 15-25 parts of cynanchum glaucescens, 15-25 parts of poria cocos, 20-25 parts of radix stemonae, 15-25 parts of honeysuckle, 15-25 parts of fried almond, 15-25 parts of platycodon grandiflorum, 15-25 parts of exocarpium citri rubrum, 10-15 parts of mangnolia officinalis, 10-15 parts of adenophora tetraphylla and 10-15 parts of common andrographis herb.
2. The pharmaceutical composition for treating chronic bronchitis asthma according to claim 1, which is prepared from the following raw materials in parts by weight: 15 parts of bighead atractylodes rhizome, 20 parts of codonopsis pilosula, 10 parts of weeping forsythia, 10 parts of radix bupleuri, 15 parts of liquorice, 20 parts of ephedra, 10 parts of elecampane, 15 parts of aster, 15 parts of cynanchum glaucescens, 15 parts of poria cocos, 20 parts of radix stemonae, 15 parts of honeysuckle, 15 parts of fried almond, 15 parts of platycodon grandiflorum, 15 parts of exocarpium citri rubrum, 10 parts of mangnolia officinalis, 10 parts of adenophora tetraphylla and 10 parts of common andrographis herb.
3. The pharmaceutical composition for treating chronic bronchitis asthma according to claim 1, which is prepared from the following raw materials in parts by weight: 25 parts of bighead atractylodes rhizome, 25 parts of codonopsis pilosula, 25 parts of weeping forsythia, 15 parts of radix bupleuri, 25 parts of liquorice, 25 parts of ephedra, 20 parts of elecampane, 25 parts of aster, 25 parts of cynanchum glaucescens, 25 parts of poria cocos, 25 parts of radix stemonae, 25 parts of honeysuckle, 25 parts of fried almond, 25 parts of platycodon grandiflorum, 25 parts of exocarpium citri rubrum, 15 parts of mangnolia officinalis, 15 parts of adenophora tetraphylla and 15 parts of common andrographis herb.
4. A process for the preparation of a pharmaceutical composition according to any one of claims 1 to 3 for the treatment of chronic bronchitis asthma, said process comprising the steps of:
s1: mixing all the raw materials, and soaking in cold water until the water submerges the medicinal materials by 5 cm;
s2: boiling the mixture obtained in the last step with strong fire, decocting with slow fire, and performing solid-liquid separation;
s3: taking out the liquid obtained by solid-liquid separation, and vacuum packaging in three equal parts for later use.
5. The method for preparing a pharmaceutical composition for the treatment of chronic bronchitis asthma according to claim 4, wherein said cold water is soaked in said step S1 for 5-6 hours.
6. The method for preparing a pharmaceutical composition for treating chronic bronchitis asthma according to any one of claims 1 to 3, wherein said step S2 is carried out by decocting with slow fire for 40 minutes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010336544.0A CN113546143A (en) | 2020-04-26 | 2020-04-26 | Pharmaceutical composition for treating chronic bronchitis asthma and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN202010336544.0A CN113546143A (en) | 2020-04-26 | 2020-04-26 | Pharmaceutical composition for treating chronic bronchitis asthma and preparation method thereof |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102716235A (en) * | 2012-06-18 | 2012-10-10 | 天津开发区经经新优技术产品开发有限公司 | Chinese medicine decoction used for tonifying qi and relieving asthma and taken for one agent per day |
| CN103638405A (en) * | 2013-12-05 | 2014-03-19 | 甘肃陇神戎发药业股份有限公司 | Ephedra and bitter apricot kernel cough capsule and preparation technology thereof |
| CN103920106A (en) * | 2014-01-17 | 2014-07-16 | 赵庆军 | Traditional Chinese medicinal composition for treating bronchitis and bronchial asthma |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102716235A (en) * | 2012-06-18 | 2012-10-10 | 天津开发区经经新优技术产品开发有限公司 | Chinese medicine decoction used for tonifying qi and relieving asthma and taken for one agent per day |
| CN103638405A (en) * | 2013-12-05 | 2014-03-19 | 甘肃陇神戎发药业股份有限公司 | Ephedra and bitter apricot kernel cough capsule and preparation technology thereof |
| CN103920106A (en) * | 2014-01-17 | 2014-07-16 | 赵庆军 | Traditional Chinese medicinal composition for treating bronchitis and bronchial asthma |
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