CN1135391C - 分析物的测定装置 - Google Patents
分析物的测定装置 Download PDFInfo
- Publication number
- CN1135391C CN1135391C CNB998116998A CN99811699A CN1135391C CN 1135391 C CN1135391 C CN 1135391C CN B998116998 A CNB998116998 A CN B998116998A CN 99811699 A CN99811699 A CN 99811699A CN 1135391 C CN1135391 C CN 1135391C
- Authority
- CN
- China
- Prior art keywords
- mark
- analyte
- trapping region
- antibody
- zone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000013508 migration Methods 0.000 title abstract description 16
- 230000005012 migration Effects 0.000 title abstract description 16
- 238000003556 assay Methods 0.000 title 1
- 239000012491 analyte Substances 0.000 claims abstract description 46
- 239000000020 Nitrocellulose Substances 0.000 claims description 15
- 229920001220 nitrocellulos Polymers 0.000 claims description 15
- 238000012360 testing method Methods 0.000 claims description 13
- 230000009471 action Effects 0.000 claims description 6
- 238000004458 analytical method Methods 0.000 claims description 4
- 230000000813 microbial effect Effects 0.000 claims description 4
- 102100022002 CD59 glycoprotein Human genes 0.000 claims description 3
- 101000897400 Homo sapiens CD59 glycoprotein Proteins 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims 1
- 239000011148 porous material Substances 0.000 abstract description 5
- 238000002372 labelling Methods 0.000 abstract 3
- 239000000523 sample Substances 0.000 description 23
- 239000002250 absorbent Substances 0.000 description 14
- 230000002745 absorbent Effects 0.000 description 14
- 239000000463 material Substances 0.000 description 8
- JKMHFZQWWAIEOD-UHFFFAOYSA-N 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid Chemical compound OCC[NH+]1CCN(CCS([O-])(=O)=O)CC1 JKMHFZQWWAIEOD-UHFFFAOYSA-N 0.000 description 7
- 239000007995 HEPES buffer Substances 0.000 description 7
- 239000000427 antigen Substances 0.000 description 5
- 102000036639 antigens Human genes 0.000 description 5
- 108091007433 antigens Proteins 0.000 description 5
- 239000006172 buffering agent Substances 0.000 description 5
- 238000001514 detection method Methods 0.000 description 4
- 229920001903 high density polyethylene Polymers 0.000 description 4
- 239000004700 high-density polyethylene Substances 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 150000002168 ethanoic acid esters Chemical class 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 210000000582 semen Anatomy 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 229920002113 octoxynol Polymers 0.000 description 2
- 229920006395 saturated elastomer Polymers 0.000 description 2
- 230000011218 segmentation Effects 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- -1 (for example Proteins 0.000 description 1
- 241000283707 Capra Species 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 229920004934 Dacron® Polymers 0.000 description 1
- 101000918657 Homo sapiens L-xylulose reductase Proteins 0.000 description 1
- 108060003951 Immunoglobulin Proteins 0.000 description 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 description 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 description 1
- 102100029137 L-xylulose reductase Human genes 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 241000235342 Saccharomycetes Species 0.000 description 1
- 239000005557 antagonist Substances 0.000 description 1
- 230000000469 anti-sperm effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
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- 239000003086 colorant Substances 0.000 description 1
- 239000013068 control sample Substances 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 231100000673 dose–response relationship Toxicity 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000000688 enterotoxigenic effect Effects 0.000 description 1
- YQGOJNYOYNNSMM-UHFFFAOYSA-N eosin Chemical compound [Na+].OC(=O)C1=CC=CC=C1C1=C2C=C(Br)C(=O)C(Br)=C2OC2=C(Br)C(O)=C(Br)C=C21 YQGOJNYOYNNSMM-UHFFFAOYSA-N 0.000 description 1
- 230000035558 fertility Effects 0.000 description 1
- 239000002657 fibrous material Substances 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 238000003312 immunocapture Methods 0.000 description 1
- 102000018358 immunoglobulin Human genes 0.000 description 1
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- 238000001764 infiltration Methods 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000016087 ovulation Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
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- 229920003023 plastic Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
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- 238000003908 quality control method Methods 0.000 description 1
- 238000012113 quantitative test Methods 0.000 description 1
- 239000000700 radioactive tracer Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 230000021595 spermatogenesis Effects 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000000528 statistical test Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
- G01N33/54388—Immunochromatographic test strips based on lateral flow
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/805—Test papers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/81—Tube, bottle, or dipstick
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Pyrane Compounds (AREA)
- Steroid Compounds (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Gyroscopes (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
- Cereal-Derived Products (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9821526.2A GB9821526D0 (en) | 1998-10-02 | 1998-10-02 | Capture assay |
| GB9821526.2 | 1998-10-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1321247A CN1321247A (zh) | 2001-11-07 |
| CN1135391C true CN1135391C (zh) | 2004-01-21 |
Family
ID=10839909
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB998116998A Expired - Fee Related CN1135391C (zh) | 1998-10-02 | 1999-10-01 | 分析物的测定装置 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US6472226B1 (de) |
| EP (2) | EP1117997B1 (de) |
| JP (1) | JP4406510B2 (de) |
| CN (1) | CN1135391C (de) |
| AT (1) | ATE223054T1 (de) |
| AU (1) | AU759117B2 (de) |
| BR (1) | BR9914112A (de) |
| CA (1) | CA2338796A1 (de) |
| DE (1) | DE69902676T2 (de) |
| ES (1) | ES2182570T3 (de) |
| GB (2) | GB9821526D0 (de) |
| WO (1) | WO2000020866A1 (de) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7211255B2 (en) * | 1996-01-29 | 2007-05-01 | United States Of America The U.S. Environmental Protection Agency | Contraceptives based on SP22 and SP22 antibodies |
| DE19927783A1 (de) * | 1999-06-18 | 2000-12-21 | Roche Diagnostics Gmbh | Element zur Bestimmung eines Analyts in einer Flüssigkeit, entsprechendes Bestimmungsverfahren unter Verwendung des Elementes sowie Kit zur Bestimmugn eines Analyts |
| GB9925461D0 (en) * | 1999-10-27 | 1999-12-29 | Genosis Ltd | Assay device |
| GB0008124D0 (en) * | 2000-04-03 | 2000-05-24 | Genosis Ltd | Capture assay |
| US6837171B1 (en) | 2002-04-29 | 2005-01-04 | Palmer/Snyder Furniture Company | Lightweight table with unitized table top |
| US8367013B2 (en) | 2001-12-24 | 2013-02-05 | Kimberly-Clark Worldwide, Inc. | Reading device, method, and system for conducting lateral flow assays |
| US20030119203A1 (en) | 2001-12-24 | 2003-06-26 | Kimberly-Clark Worldwide, Inc. | Lateral flow assay devices and methods for conducting assays |
| US7285424B2 (en) | 2002-08-27 | 2007-10-23 | Kimberly-Clark Worldwide, Inc. | Membrane-based assay devices |
| EP1537416A1 (de) * | 2002-09-11 | 2005-06-08 | Lattec I/S | Einrichtung zur analyse von analytzusammensetzungen und verwendung dafür |
| US7781172B2 (en) | 2003-11-21 | 2010-08-24 | Kimberly-Clark Worldwide, Inc. | Method for extending the dynamic detection range of assay devices |
| US7247500B2 (en) | 2002-12-19 | 2007-07-24 | Kimberly-Clark Worldwide, Inc. | Reduction of the hook effect in membrane-based assay devices |
| WO2004081528A2 (en) * | 2003-03-10 | 2004-09-23 | Robinson Joseph R | Assay device and method |
| US20040197819A1 (en) | 2003-04-03 | 2004-10-07 | Kimberly-Clark Worldwide, Inc. | Assay devices that utilize hollow particles |
| US7851209B2 (en) | 2003-04-03 | 2010-12-14 | Kimberly-Clark Worldwide, Inc. | Reduction of the hook effect in assay devices |
| US7393697B2 (en) | 2003-06-06 | 2008-07-01 | Advantage Diagnostics Corporation | Diagnostic test for analytes in a sample |
| US7107936B2 (en) * | 2003-09-04 | 2006-09-19 | Mmi Genomics, Inc. | Device and method for animal tracking |
| US7713748B2 (en) | 2003-11-21 | 2010-05-11 | Kimberly-Clark Worldwide, Inc. | Method of reducing the sensitivity of assay devices |
| US7943395B2 (en) | 2003-11-21 | 2011-05-17 | Kimberly-Clark Worldwide, Inc. | Extension of the dynamic detection range of assay devices |
| US20050112703A1 (en) | 2003-11-21 | 2005-05-26 | Kimberly-Clark Worldwide, Inc. | Membrane-based lateral flow assay devices that utilize phosphorescent detection |
| US7943089B2 (en) | 2003-12-19 | 2011-05-17 | Kimberly-Clark Worldwide, Inc. | Laminated assay devices |
| US20050221386A1 (en) * | 2004-02-17 | 2005-10-06 | Turner Nathan B | Chromatographic exclusion agglutination assay and methods of use thereof |
| JP4616575B2 (ja) * | 2004-04-14 | 2011-01-19 | デンカ生研株式会社 | タンパク質の膜固定化方法 |
| US20060019406A1 (en) * | 2004-07-23 | 2006-01-26 | Ning Wei | Lateral flow device for the detection of large pathogens |
| US7442557B1 (en) * | 2004-10-22 | 2008-10-28 | Idexx Laboratories, Inc. | Bi-directional flow assay device with reagent bridge |
| JP4547272B2 (ja) * | 2005-01-12 | 2010-09-22 | シスメックス株式会社 | イムノクロマトグラフィー用試験具 |
| US7189522B2 (en) | 2005-03-11 | 2007-03-13 | Chembio Diagnostic Systems, Inc. | Dual path immunoassay device |
| WO2006098804A2 (en) | 2005-03-11 | 2006-09-21 | Chembio Diagnostic Systems, Inc. | Dual path immunoassay device |
| AU2006313611B2 (en) * | 2005-11-12 | 2013-01-31 | Platform Diagnostics Limited | Agglutination assay |
| WO2007095530A2 (en) * | 2006-02-13 | 2007-08-23 | U.S. Environmental Protection Agency | Diagnostic kits to detect sp22 and sp22 antibodies |
| US7704702B2 (en) * | 2006-08-10 | 2010-04-27 | Inverness Medical Switzerland Gmbh | Test strip for lateral flow assays |
| GB2443694B (en) * | 2006-11-10 | 2011-09-14 | Platform Diagnostics Ltd | Analyte saturation assay, methods and kits and devices |
| US8865454B2 (en) | 2007-03-22 | 2014-10-21 | Scandinavian Micro Biodevices Aps | Flow through system, flow through device and a method of performing a test |
| CN101435823B (zh) * | 2007-11-12 | 2012-08-08 | 无锡中德伯尔生物技术有限公司 | 检测残留兽药的荧光微球免疫层析试纸条及其制备方法 |
| US20090263905A1 (en) * | 2008-04-18 | 2009-10-22 | Kim Scheuringer | Detection test assembly for detecting the presence of a substance in a sample |
| CN102084238B (zh) * | 2008-05-05 | 2016-06-01 | 洛斯阿拉莫斯国家安全有限责任公司 | 基于高度简化的侧向流动的核酸样品制备和被动流体流动控制 |
| US20100022916A1 (en) | 2008-07-24 | 2010-01-28 | Javanbakhsh Esfandiari | Method and Apparatus for Collecting and Preparing Biological Samples for Testing |
| US8828329B2 (en) | 2010-10-01 | 2014-09-09 | Church & Dwight, Co., Inc. | Electronic analyte assaying device |
| US8603835B2 (en) | 2011-02-10 | 2013-12-10 | Chembio Diagnostic Systems, Inc. | Reduced step dual path immunoassay device and method |
| CN103323590B (zh) * | 2013-06-08 | 2015-05-06 | 上海云泽生物科技有限公司 | 一种基于纤维膜捕集分离的定量检测装置及其检测方法 |
| SG11201608278WA (en) | 2014-04-02 | 2016-10-28 | Chembio Diagnostic Systems Inc | Immunoassay utilizing trapping conjugate |
| CN105004855B (zh) * | 2014-04-16 | 2017-05-31 | 万冰 | 一种侧向流动检测测试条 |
| US20160116466A1 (en) | 2014-10-27 | 2016-04-28 | Chembio Diagnostic Systems, Inc. | Rapid Screening Assay for Qualitative Detection of Multiple Febrile Illnesses |
| US9981264B2 (en) | 2014-11-04 | 2018-05-29 | Grace Bio-Labs, Inc. | Nitrocellulose extrusion for porous film strips |
| US20190145966A1 (en) * | 2016-04-12 | 2019-05-16 | Meje Ab | Membrane-based analytical device for bodily fluids |
| JP6939106B2 (ja) * | 2017-06-09 | 2021-09-22 | 東洋紡株式会社 | イムノクロマト試験片およびキットおよび測定方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5763262A (en) * | 1986-09-18 | 1998-06-09 | Quidel Corporation | Immunodiagnostic device |
| US5310650A (en) * | 1986-09-29 | 1994-05-10 | Abbott Laboratoires | Method and device for improved reaction kinetics in nucleic acid hybridizations |
| US4857453A (en) * | 1987-04-07 | 1989-08-15 | Syntex (U.S.A.) Inc. | Immunoassay device |
| DE291194T1 (de) * | 1987-04-27 | 1992-03-19 | Unilever N.V., Rotterdam | Immunoassays und vorrichtungen dafuer. |
| JPS63305251A (ja) * | 1987-06-05 | 1988-12-13 | Dai Ichi Pure Chem Co Ltd | ラテツクス凝集反応を利用する免疫学的測定方法 |
| US5244630A (en) * | 1988-04-22 | 1993-09-14 | Abbott Laboratories | Device for performing solid-phase diagnostic assay |
| US5232834A (en) * | 1989-03-15 | 1993-08-03 | Fuso Pharmaceutical Industries, Ltd. | Anti-human sperm antibody, and its production and use |
| AU636875B2 (en) * | 1989-03-17 | 1993-05-13 | Abbott Laboratories | Method and device for improved reaction kinetics in nucleic acid hybridizations |
| US5087556A (en) * | 1989-05-17 | 1992-02-11 | Actimed Laboratories, Inc. | Method for quantitative analysis of body fluid constituents |
| WO1994016329A1 (en) * | 1993-01-13 | 1994-07-21 | Abbott Laboratories | Methods for solid phase capture in immunoassays |
| US5424193A (en) * | 1993-02-25 | 1995-06-13 | Quidel Corporation | Assays employing dyed microorganism labels |
| ES2268706T3 (es) * | 1995-05-09 | 2007-03-16 | Beckman Coulter, Inc. | Dispositivos y procedimientos para separar componentes celulares de la sangre de la porcion liquida de la sangre. |
| WO1996036878A1 (en) * | 1995-05-19 | 1996-11-21 | Universal Healthwatch, Inc. | Rapid self-contained assay format |
| AU6720096A (en) * | 1995-08-09 | 1997-03-05 | Quidel Corporation | Test strip and method for one step lateral flow assay |
| US5741662A (en) * | 1995-12-18 | 1998-04-21 | Quidel Corporation | Direct stain specific binding assays for microorganisms |
| WO1997031259A1 (en) * | 1996-02-22 | 1997-08-28 | Dexall Biomedical Labs, Inc. | Non-captive substrate liquid phase immunoassay |
| DE19629656A1 (de) * | 1996-07-23 | 1998-01-29 | Boehringer Mannheim Gmbh | Diagnostischer Testträger mit mehrschichtigem Testfeld und Verfahren zur Bestimmung von Analyt mit dessen Hilfe |
| US6753189B1 (en) * | 1998-06-04 | 2004-06-22 | Mizuho Medy Co., Ltd. | Detection apparatus and method for the same |
-
1998
- 1998-10-02 GB GBGB9821526.2A patent/GB9821526D0/en not_active Ceased
-
1999
- 1999-10-01 JP JP2000574933A patent/JP4406510B2/ja not_active Expired - Fee Related
- 1999-10-01 CA CA002338796A patent/CA2338796A1/en not_active Abandoned
- 1999-10-01 GB GB0008683A patent/GB2345964B/en not_active Expired - Fee Related
- 1999-10-01 BR BR9914112-4A patent/BR9914112A/pt not_active Application Discontinuation
- 1999-10-01 AU AU61089/99A patent/AU759117B2/en not_active Ceased
- 1999-10-01 AT AT99947714T patent/ATE223054T1/de not_active IP Right Cessation
- 1999-10-01 CN CNB998116998A patent/CN1135391C/zh not_active Expired - Fee Related
- 1999-10-01 DE DE69902676T patent/DE69902676T2/de not_active Expired - Lifetime
- 1999-10-01 EP EP99947714A patent/EP1117997B1/de not_active Expired - Lifetime
- 1999-10-01 EP EP02078350A patent/EP1281968A3/de not_active Withdrawn
- 1999-10-01 ES ES99947714T patent/ES2182570T3/es not_active Expired - Lifetime
- 1999-10-01 WO PCT/GB1999/003249 patent/WO2000020866A1/en active IP Right Grant
-
2000
- 2000-09-08 US US09/658,148 patent/US6472226B1/en not_active Expired - Lifetime
-
2002
- 2002-05-13 US US10/145,170 patent/US7211403B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2338796A1 (en) | 2000-04-13 |
| GB9821526D0 (en) | 1998-11-25 |
| DE69902676D1 (de) | 2002-10-02 |
| WO2000020866A1 (en) | 2000-04-13 |
| ES2182570T3 (es) | 2003-03-01 |
| EP1117997B1 (de) | 2002-08-28 |
| EP1281968A2 (de) | 2003-02-05 |
| DE69902676T2 (de) | 2003-04-24 |
| ATE223054T1 (de) | 2002-09-15 |
| GB0008683D0 (en) | 2000-05-31 |
| BR9914112A (pt) | 2001-06-12 |
| AU759117B2 (en) | 2003-04-03 |
| US6472226B1 (en) | 2002-10-29 |
| CN1321247A (zh) | 2001-11-07 |
| GB2345964A (en) | 2000-07-26 |
| US7211403B2 (en) | 2007-05-01 |
| JP4406510B2 (ja) | 2010-01-27 |
| EP1281968A3 (de) | 2003-05-14 |
| EP1117997A1 (de) | 2001-07-25 |
| US20020127614A1 (en) | 2002-09-12 |
| GB2345964B (en) | 2000-12-06 |
| JP2002526774A (ja) | 2002-08-20 |
| AU6108999A (en) | 2000-04-26 |
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