CN113473856B - 防腐剂组合物及其使用方法 - Google Patents
防腐剂组合物及其使用方法 Download PDFInfo
- Publication number
- CN113473856B CN113473856B CN202080015715.8A CN202080015715A CN113473856B CN 113473856 B CN113473856 B CN 113473856B CN 202080015715 A CN202080015715 A CN 202080015715A CN 113473856 B CN113473856 B CN 113473856B
- Authority
- CN
- China
- Prior art keywords
- product
- enzyme
- cross
- chitosan
- polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/50—Isolated enzymes; Isolated proteins
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
- A01N25/10—Macromolecular compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
- A01N25/28—Microcapsules or nanocapsules
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P1/00—Disinfectants; Antimicrobial compounds or mixtures thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/104—Aminoacyltransferases (2.3.2)
- C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/524—Preservatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/02—Aminoacyltransferases (2.3.2)
- C12Y203/02013—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Medicinal Chemistry (AREA)
- Birds (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Enzymes And Modification Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962814582P | 2019-03-06 | 2019-03-06 | |
| US62/814,582 | 2019-03-06 | ||
| PCT/US2020/021211 WO2020181099A1 (en) | 2019-03-06 | 2020-03-05 | Preservative compositions and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN113473856A CN113473856A (zh) | 2021-10-01 |
| CN113473856B true CN113473856B (zh) | 2024-03-19 |
Family
ID=72338742
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202080015715.8A Active CN113473856B (zh) | 2019-03-06 | 2020-03-05 | 防腐剂组合物及其使用方法 |
| CN202080098053.5A Pending CN115210368A (zh) | 2019-03-06 | 2020-09-03 | 衍生自酶原和蛋白质原的成熟多肽的无细胞蛋白质表达方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202080098053.5A Pending CN115210368A (zh) | 2019-03-06 | 2020-09-03 | 衍生自酶原和蛋白质原的成熟多肽的无细胞蛋白质表达方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US12256741B2 (enExample) |
| EP (1) | EP3934426A4 (enExample) |
| JP (2) | JP2022522502A (enExample) |
| KR (1) | KR20210137010A (enExample) |
| CN (2) | CN113473856B (enExample) |
| BR (1) | BR112021017128A2 (enExample) |
| CA (2) | CA3128374A1 (enExample) |
| WO (1) | WO2020181099A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021183680A1 (en) * | 2020-03-13 | 2021-09-16 | Curie Co. Inc. | Transglutaminase variants |
| US20230329245A1 (en) | 2020-09-08 | 2023-10-19 | Curie Co. Inc. | Compositions and methods of use thereof |
| KR102463904B1 (ko) * | 2020-10-05 | 2022-11-03 | 김미경 | 구리, 아연, 천연물 및 다공성 담체 이용 바이오 항균 원료 및 항균 제품 |
| CN115531239B (zh) * | 2022-05-19 | 2023-12-12 | 海默斯(重庆)医学生物技术有限公司 | 纳米颗粒、牙膏及其制备方法 |
| WO2023225666A1 (en) | 2022-05-20 | 2023-11-23 | Curie Co. Inc. | Pro-peptide variants for modulating activity of transglutaminases |
| WO2024243088A1 (en) | 2023-05-19 | 2024-11-28 | Curie Co. Inc. | Transglutaminases and uses thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3284212A (en) * | 1963-03-06 | 1966-11-08 | Flavor Corp Of America | Food preservative comprising enzymes and antioxidants |
| JPH09149784A (ja) * | 1995-11-29 | 1997-06-10 | New Japan Radio Co Ltd | プロテアーゼ活性計測用センサ |
| CN101600835A (zh) * | 2006-11-22 | 2009-12-09 | 丰田自动车工程及制造北美公司 | 生物功能材料 |
| CN102762668A (zh) * | 2009-12-23 | 2012-10-31 | 莫门蒂夫性能材料股份有限公司 | 网络共聚物交联的组合物以及包含其的产品 |
| EP3272864A1 (en) * | 2016-07-20 | 2018-01-24 | Paul Scherrer Institut | Solid-phase immobilization of microbial transglutaminase mtg on microbeads for protein conjugation |
| CN108157582A (zh) * | 2017-12-12 | 2018-06-15 | 河南省农业科学院 | 一种利用固定化酶改性提高芝麻蛋白凝胶性的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3940816B2 (ja) | 1999-08-30 | 2007-07-04 | 株式会社ニチロ | 蛋白素材を含有する食品又は飼料の保存性を向上させた製造方法とそのための食品又は飼料の添加組成物 |
| US6433078B1 (en) | 2000-10-23 | 2002-08-13 | Polium Technologies, Inc. | Reversibly soluble enzyme-polymer conjugates |
| KR100550385B1 (ko) | 2002-11-11 | 2006-02-08 | 메타볼랩(주) | 트랜스글루타미나아제를 포함하는 칸디다 속의 미생물과그의 숙주 세포 사이의 결합 저해제 |
| PT1893187E (pt) * | 2005-06-13 | 2009-02-24 | Flen Pharma N V | Dispositivo para próprio aumentar o grau de segurança de portas ou de elementos semelhantes a portas contra tentativas de arrombamento |
| CN110241106A (zh) | 2011-11-11 | 2019-09-17 | 吉尔德联合有限公司 | 一种可生物降解的固定化酶及其制备方法 |
| JP6110157B2 (ja) | 2013-02-15 | 2017-04-05 | 日清食品冷凍株式会社 | 生めん類及びその結着抑制方法 |
| CN104522117A (zh) | 2014-12-31 | 2015-04-22 | 山东圣琪生物有限公司 | 一种面包保鲜剂及制备方法 |
-
2020
- 2020-03-05 JP JP2021551863A patent/JP2022522502A/ja active Pending
- 2020-03-05 US US17/436,542 patent/US12256741B2/en active Active
- 2020-03-05 BR BR112021017128A patent/BR112021017128A2/pt unknown
- 2020-03-05 KR KR1020217027615A patent/KR20210137010A/ko not_active Ceased
- 2020-03-05 WO PCT/US2020/021211 patent/WO2020181099A1/en not_active Ceased
- 2020-03-05 EP EP20766684.3A patent/EP3934426A4/en active Pending
- 2020-03-05 CA CA3128374A patent/CA3128374A1/en active Pending
- 2020-03-05 CN CN202080015715.8A patent/CN113473856B/zh active Active
- 2020-09-03 CA CA3172787A patent/CA3172787A1/en active Pending
- 2020-09-03 US US17/909,177 patent/US20230114779A1/en not_active Abandoned
- 2020-09-03 JP JP2022552709A patent/JP2023516355A/ja active Pending
- 2020-09-03 CN CN202080098053.5A patent/CN115210368A/zh active Pending
-
2025
- 2025-02-18 US US19/055,805 patent/US20250185671A1/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3284212A (en) * | 1963-03-06 | 1966-11-08 | Flavor Corp Of America | Food preservative comprising enzymes and antioxidants |
| JPH09149784A (ja) * | 1995-11-29 | 1997-06-10 | New Japan Radio Co Ltd | プロテアーゼ活性計測用センサ |
| CN101600835A (zh) * | 2006-11-22 | 2009-12-09 | 丰田自动车工程及制造北美公司 | 生物功能材料 |
| CN102762668A (zh) * | 2009-12-23 | 2012-10-31 | 莫门蒂夫性能材料股份有限公司 | 网络共聚物交联的组合物以及包含其的产品 |
| EP3272864A1 (en) * | 2016-07-20 | 2018-01-24 | Paul Scherrer Institut | Solid-phase immobilization of microbial transglutaminase mtg on microbeads for protein conjugation |
| CN108157582A (zh) * | 2017-12-12 | 2018-06-15 | 河南省农业科学院 | 一种利用固定化酶改性提高芝麻蛋白凝胶性的方法 |
Non-Patent Citations (4)
| Title |
|---|
| "Immobilization of tyrosinase on chitosan-clay composite beads";Ayse Dincer等;《International Journal of Biological Macromolecules》;20111231;第50卷(第3期);摘要 * |
| "Immobilizationof tyrosinase in chitosan film for an optical detection of phenol";Jaafar Abdullah等;《Sensors and Actuators B》;20051231;第114卷(第2期);摘要、第605页左栏第4段-右栏第3段 * |
| "The Antimicrobial Activity of Marinocine, Synthesized by Marinomonas mediterranea, Is Due to Hydrogen Peroxide Generated by Its Lysine Oxidase Activity";Patricia Lucas-Elı´o等;《JOURNAL OF BACTERIOLOGY》;20061231;第188卷(第7期);摘要、第2493右栏第1段-2494左栏第1段、第2945页右栏第4段-2948页第1段、图4-图5 * |
| Patricia Lucas-Elı'o等."The Antimicrobial Activity of Marinocine, Synthesized by Marinomonas mediterranea, Is Due to Hydrogen Peroxide Generated by Its Lysine Oxidase Activity".《JOURNAL OF BACTERIOLOGY》.2006,第188卷(第7期),第2943-2501页. * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020181099A1 (en) | 2020-09-10 |
| CN113473856A (zh) | 2021-10-01 |
| EP3934426A4 (en) | 2022-12-14 |
| CA3128374A1 (en) | 2020-09-10 |
| US20250185671A1 (en) | 2025-06-12 |
| JP2023516355A (ja) | 2023-04-19 |
| JP2022522502A (ja) | 2022-04-19 |
| KR20210137010A (ko) | 2021-11-17 |
| BR112021017128A2 (pt) | 2021-11-03 |
| CN115210368A (zh) | 2022-10-18 |
| US20220117236A1 (en) | 2022-04-21 |
| US12256741B2 (en) | 2025-03-25 |
| EP3934426A1 (en) | 2022-01-12 |
| US20230114779A1 (en) | 2023-04-13 |
| CA3172787A1 (en) | 2021-09-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN113473856B (zh) | 防腐剂组合物及其使用方法 | |
| Huq et al. | Sources, production and commercial applications of fungal chitosan: A review | |
| Hu et al. | Formation and optimization of chitosan-nisin microcapsules and its characterization for antibacterial activity | |
| Aljawish et al. | Laccase-catalysed functionalisation of chitosan by ferulic acid and ethyl ferulate: Evaluation of physicochemical and biofunctional properties | |
| ES2718608T3 (es) | Composición germicida formadora de película de barrera para el control de la mastitis | |
| Li et al. | Design, synthesis and characterization of lysozyme–gentisic acid dual-functional conjugates with antibacterial/antioxidant activities | |
| US6406897B1 (en) | Modified protein, method for preparation thereof and compositions for external application containing the modified protein | |
| Mahae et al. | Antioxidant and antimicrobial properties of chitosan-sugar complex | |
| JP2023518714A (ja) | トランスグルタミナーゼ変種 | |
| US20230203457A1 (en) | Transglutaminase variants and applications of use thereof | |
| ES2503340T3 (es) | Composiciones a base de Arthrospira y usos de los mismos | |
| Zhu et al. | Preparation, characterization, and antibacterial and antioxidant activities of caffeic acid grafted ε-polylysine | |
| KR101975806B1 (ko) | 갑각류 및 포유 동물의 면역력 증강 사료 첨가용 조성물 및 이의 제조방법 | |
| CA2920768C (en) | Sea lice treatment | |
| Cynthya et al. | Papain immobilized polyurethane film as antimicrobial food package | |
| Roy et al. | Sustainable novel food coating of Chitosan–acetylated gallic acid nanoparticles with pulsed light treatment: a Promising Edible Food Preservative | |
| JP5044190B2 (ja) | バチルス属細菌の殺菌方法又は溶菌方法とその利用 | |
| Sharma et al. | Antimicrobial efficacy and safety of mucoadhesive exopolymer produced by Acinetobacter haemolyticus | |
| Rajagopal et al. | Extraction of chitin and chitosan from marine waste and its applications on food and agriculture products | |
| WO2024243088A1 (en) | Transglutaminases and uses thereof | |
| JP2008154456A (ja) | タンパク質分解酵素 | |
| CA2134346A1 (en) | Undecylenic acid derivatives with hydrophilic molecules and utilizations in cosmetics or in pharmacy | |
| CN114223828A (zh) | 一种绿色食品级生物杀菌剂 | |
| Bridle | Antimicrobial efficacy and safety of mucoadhesive | |
| Kara | Zeytin yaprağı tozu ve bor katkılı polipropilen kompozitleri |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |