CN113454459A - 诊断方法 - Google Patents

诊断方法 Download PDF

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Publication number
CN113454459A
CN113454459A CN202080015187.6A CN202080015187A CN113454459A CN 113454459 A CN113454459 A CN 113454459A CN 202080015187 A CN202080015187 A CN 202080015187A CN 113454459 A CN113454459 A CN 113454459A
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CN
China
Prior art keywords
subject
adiponectin
antibody
pancreatitis
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202080015187.6A
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English (en)
Chinese (zh)
Inventor
E·科斯特洛
W·格林哈尔弗
L·奥德菲尔德
C·哈洛伦
P·加奈
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Liverpool
Original Assignee
University of Liverpool
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1902193.0A external-priority patent/GB201902193D0/en
Priority claimed from GBGB1903424.8A external-priority patent/GB201903424D0/en
Application filed by University of Liverpool filed Critical University of Liverpool
Publication of CN113454459A publication Critical patent/CN113454459A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57525—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the liver or pancreas
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/067—Pancreatitis or colitis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
CN202080015187.6A 2019-02-18 2020-02-17 诊断方法 Pending CN113454459A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB1902193.0A GB201902193D0 (en) 2019-02-18 2019-02-18 Method of diagnosis
GB1902193.0 2019-02-18
GB1903424.8 2019-03-13
GBGB1903424.8A GB201903424D0 (en) 2019-03-13 2019-03-13 Method of diagnosis
PCT/EP2020/054046 WO2020169511A1 (en) 2019-02-18 2020-02-17 Method of diagnosis

Publications (1)

Publication Number Publication Date
CN113454459A true CN113454459A (zh) 2021-09-28

Family

ID=69591656

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080015187.6A Pending CN113454459A (zh) 2019-02-18 2020-02-17 诊断方法

Country Status (7)

Country Link
US (1) US20220091140A1 (https=)
EP (1) EP3903105A1 (https=)
JP (1) JP7660077B2 (https=)
CN (1) CN113454459A (https=)
AU (1) AU2020223826A1 (https=)
CA (1) CA3127569A1 (https=)
WO (1) WO2020169511A1 (https=)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108138238A (zh) * 2015-07-28 2018-06-08 约翰霍普金斯大学 用于检测胰腺癌的组合物和方法

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* Cited by examiner, † Cited by third party
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DK1426764T3 (da) * 2001-08-17 2011-06-27 Fujirebio Kk Fremgangsmåde til diagnosticering eller monitorering af fejl i sukkermetabolisme
EP1590434A4 (en) * 2003-01-17 2006-11-29 Univ New York State Res Found ASSOCIATED ANTIGEN, ANTIBODIES, AND DIAGNOSIS AND TREATMENT METHODS WITH CONCENTRATED CANNULA CANCER
US20060105419A1 (en) * 2004-08-16 2006-05-18 Biosite, Inc. Use of a glutathione peroxidase 1 as a marker in cardiovascular conditions
US8632983B2 (en) * 2005-04-15 2014-01-21 Van Andel Research Institute Biomarkers for pancreatic cancer and diagnostic methods
CA2645125A1 (en) * 2006-03-02 2007-09-13 Oncotherapy Science, Inc. Methods for diagnosing pancreatic cancer using reg4 protein
CN102939541B (zh) * 2010-06-15 2015-12-02 弗·哈夫曼-拉罗切有限公司 手术后急性肾损伤的预测和识别
JP2014510516A (ja) * 2011-02-15 2014-05-01 ノヴォ ノルディスク アー／エス 長時間作用性ｉｌ−１受容体アンタゴニスト
GB201103726D0 (en) * 2011-03-04 2011-04-20 Immunovia Ab Method, array and use thereof
JP6189754B2 (ja) * 2011-03-04 2017-08-30 イントレキソン コーポレーション タンパク質を条件的に発現するベクター
US20160231334A1 (en) * 2013-10-28 2016-08-11 The Forsyth Institute Compositions and Methods for Evaluating Metabolic Syndrome and Related Diseases
WO2015112429A1 (en) 2014-01-23 2015-07-30 Newomics Inc Methods and systems for diagnosing diseases
WO2015157557A1 (en) 2014-04-09 2015-10-15 Myriad Rbm, Inc. Methods of diagnosing pancreatic cancer and methods related thereto
BR112017002884A2 (pt) * 2014-08-14 2018-01-30 Memed Diagnostics Ltd ?análise computacional de dados biológicos por meio do uso de variedade e hiperplano?
EP3209804A4 (en) * 2014-10-22 2018-02-28 The George Washington University A Congretionally Chartered Not-For-Profit Corp. Blood biomarkers for appendicitis and diagnostics methods using biomarkers
GB201522839D0 (en) 2015-12-23 2016-02-03 Randox Lab Ltd And Randox Teoranta Method
US12416636B2 (en) * 2018-05-31 2025-09-16 University Of Florida Research Foundation, Inc. Personalized treatment of pancreatic cancer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108138238A (zh) * 2015-07-28 2018-06-08 约翰霍普金斯大学 用于检测胰腺癌的组合物和方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EWA KONTNY等: "Comparison of rheumatoid articular adipose and synovial tissue reactivity to proinfl ammatory stimuli: contribution to adipocytokine network", ANN RHEUM DIS, vol. 71, pages 262 - 267 *

Also Published As

Publication number Publication date
US20220091140A1 (en) 2022-03-24
CA3127569A1 (en) 2020-08-27
JP2022529073A (ja) 2022-06-16
JP7660077B2 (ja) 2025-04-10
WO2020169511A1 (en) 2020-08-27
AU2020223826A1 (en) 2021-08-05
EP3903105A1 (en) 2021-11-03

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