CN113440554A - Formula, preparation method and application of health-care product - Google Patents

Formula, preparation method and application of health-care product Download PDF

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Publication number
CN113440554A
CN113440554A CN202110770727.8A CN202110770727A CN113440554A CN 113440554 A CN113440554 A CN 113440554A CN 202110770727 A CN202110770727 A CN 202110770727A CN 113440554 A CN113440554 A CN 113440554A
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parts
salvia miltiorrhiza
ginseng
health
modified
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李健明
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Hangzhou Shizi Hede Biotechnology Co ltd
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Hangzhou Shizi Hede Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016Disaccharides, e.g. lactose, lactulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/074Ganoderma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The invention discloses a formula, a preparation method and application of a health-care product, wherein the formula comprises the following components in parts by weight: 3-7 parts of cicada slough, 5-15 parts of astragalus membranaceus, 5-10 parts of lucid ganoderma, 3-7 parts of mantis egg-case, 1-5 parts of spina date seed, 4-8 parts of pearl powder, 3-15 parts of ginseng, 3-9 parts of pseudo-ginseng, 10-15 parts of maltose, 4-6 parts of chrysanthemum extract and 3-8 parts of modified salvia miltiorrhiza bunge. Solves the problem that no good health-care product aiming at insomnia exists in the market.

Description

Formula, preparation method and application of health-care product
Technical Field
The invention relates to a health-care product, in particular to a formula, a preparation method and application of a health-care product.
Background
The health care product can regulate the function of a human body, is suitable for being eaten by specific people, but does not aim at treating diseases, so related words such as effective rate, success rate and the like cannot appear in the propaganda of the product. The health care function of the health care product is gradually accepted by the masses in the current society.
With the rapid development of the times and the continuous improvement of living standard, the living and working environments of people are changed greatly, the body and spirit of people are damaged due to high working pressure, unscientific living style, unhealthy diet and the like, so that the insomnia is caused, and the cicada slough has wonderful effect of treating the insomnia. The qi and blood supplement can also relieve insomnia, enhance physique, lead to deficiency of qi and blood and lack of spirit nourishment of blood, also lead to poor sleep effect and short deep sleep time, and is an expression form of insomnia.
But no good health care product aiming at insomnia exists in the market.
Disclosure of Invention
The invention aims to provide a formula, a preparation method and application of a health-care product, so as to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme:
the formula of the health-care product comprises the following components in parts by weight:
3-7 parts of cicada slough, 5-15 parts of astragalus membranaceus, 5-10 parts of lucid ganoderma, 3-7 parts of mantis egg-case, 1-5 parts of spina date seed, 4-8 parts of pearl powder, 3-15 parts of ginseng, 3-9 parts of pseudo-ginseng, 10-15 parts of maltose, 4-6 parts of chrysanthemum extract and 3-8 parts of modified salvia miltiorrhiza.
Preferably, the composition comprises the following components in parts by weight:
4-6 parts of cicada slough, 7-13 parts of astragalus membranaceus, 6-9 parts of lucid ganoderma, 4-6 parts of mantis egg-case, 2-4 parts of spina date seed, 5-7 parts of pearl powder, 5-13 parts of ginseng, 4-8 parts of pseudo-ginseng, 11-14 parts of maltose, 4.5-5.5 parts of chrysanthemum extract and 4-7 parts of modified salvia miltiorrhiza.
Preferably, the composition comprises the following components in parts by weight:
5 parts of cicada slough, 10 parts of astragalus membranaceus, 7 parts of lucid ganoderma, 5 parts of mantis egg-case, 3 parts of spina date seed, 6 parts of pearl powder, 9 parts of ginseng, 6 parts of pseudo-ginseng, 12 parts of maltose, 5 parts of chrysanthemum extract and 6 parts of modified salvia miltiorrhiza.
Preferably, the processing method of the cicada slough comprises the following steps:
taking the cicada slough according to parts, cleaning and crushing the cicada slough for standby, using rice washing water of polished round-grained rice, filtering rice grains, taking out the rice washing water, adding the rice washing water and the cicada slough powder into a medicine pot according to the weight ratio of 10:1, and decocting to obtain the cicada slough.
Preferably, the preparation method of the modified salvia miltiorrhiza comprises the following steps:
s1: cleaning and airing salvia miltiorrhiza, cutting to obtain salvia miltiorrhiza slices, soaking the salvia miltiorrhiza slices in alcohol, taking out and airing for later use;
s2: putting the treated salvia miltiorrhiza slices into a reaction vat, adding purified water and methanol, then adding citric acid, adding alkali to adjust the pH value to 9-10, and carrying out decoction reflux extraction;
s3: cooling the extracted decoction, adding acid to adjust pH, standing at room temperature, filtering, mixing filtrates, and concentrating under reduced pressure to obtain mixed solution;
s4: removing impurities from the mixed solution to obtain a salvia miltiorrhiza decoction, and concentrating the salvia miltiorrhiza decoction by a low-temperature membrane to obtain the modified salvia miltiorrhiza with the relative density of 1.02-1.03.
According to the formula of the health-care product, the processing method of the mantis egg-cases comprises the following steps:
s1: removing impurities from the collected ootheca Mantidis, and sterilizing by ultrasonic waves;
s2: putting clean ootheca Mantidis on a food steamer, steaming with slow fire for 2-5h until the insect egg dies;
s3: placing the boiled mantis egg-cases in the sun to dry completely;
s4: cutting into pieces for use.
The preparation method of the health-care product comprises the following steps:
s1: preparing raw materials, cleaning the raw materials and removing impurities for later use;
s2: adding radix astragali, Ganoderma, ootheca Mantidis, semen Ziziphi Spinosae, Margarita powder, Ginseng radix, and Notoginseng radix into reaction jar, adding water, stirring, heating to 110-;
s3: mixing periostracum Cicadae liquid medicine and mixed medicinal liquid, stirring well, adding into modified Saviae Miltiorrhizae radix, adding maltose and flos Chrysanthemi extract according to parts, mixing well, and processing and shaping to obtain the final product.
The formula of the health-care product is applied to preparing the medicine for relieving insomnia.
The formula of the health-care product is applied to the preparation of the medicine for enhancing qi and blood, tonifying kidney and supporting yang.
Compared with the prior art, the invention has the beneficial effects that:
the health-care product has the effect of relieving insomnia by adding the cicada slough and the modified salvia miltiorrhiza.
Detailed Description
The technical solution of the present invention will be described in further detail with reference to specific embodiments.
Example 1
Firstly, preparing raw materials, wherein the raw materials comprise: 5g of cicada slough, 10g of astragalus membranaceus, 7g of lucid ganoderma, 5g of mantis egg-case, 3g of spina date seeds, 6g of pearl powder, 9g of ginseng, 6g of pseudo-ginseng, 12g of maltose, 5g of chrysanthemum extract and 6g of modified salvia miltiorrhiza, and the raw materials are cleaned and subjected to impurity removal for later use; then, ootheca mantidis is processed: removing impurities from the collected ootheca Mantidis, and sterilizing by ultrasonic waves; putting clean ootheca Mantidis on a food steamer, and steaming with slow fire for 2h until worm eggs die; placing the boiled ootheca Mantidis in the sun for airing for 2d until the ootheca Mantidis is completely dried; cutting into pieces for later use; then, preparing modified salvia miltiorrhiza: cleaning Saviae Miltiorrhizae radix, air drying, slicing to obtain Saviae Miltiorrhizae radix slice, soaking in 90% ethanol for 8min, taking out, and air drying; putting the treated salvia miltiorrhiza slices into a reaction vat, adding purified water and methanol, then adding citric acid, adding alkali to adjust the pH value to 9, and carrying out decoction reflux extraction; cooling the extracted decoction, adding acid to adjust pH to 2, standing at room temperature for 10h, filtering, mixing filtrates, and concentrating under reduced pressure to obtain mixed solution; removing impurities from the mixed solution to obtain a salvia miltiorrhiza decoction, and concentrating the salvia miltiorrhiza decoction by a low-temperature membrane to obtain modified salvia miltiorrhiza; next, cicada slough is processed: taking periostracum Cicadae according to a ratio, cleaning and crushing the periostracum Cicadae for later use, using rice washing water of polished round-grained rice, filtering rice grains, taking out the rice washing water, adding the rice washing water and the periostracum Cicadae powder into a medicine pot according to a weight ratio of 10:1, decocting for 10min with strong fire, turning to mild fire for decocting for 6h after water is boiled, and filtering out medicine liquid for later use; next, adding the astragalus, the lucid ganoderma, the mantis egg-case, the spina date seed, the pearl powder, the ginseng and the pseudo-ginseng into a reaction vat according to the proportion, adding water, stirring and heating, stopping heating when the temperature is raised to 120 ℃, stopping heating after 4 hours, cooling at normal temperature, and filtering out mixed medicine juice for later use; and finally, uniformly stirring the cicada slough liquid medicine and the mixed liquid medicine, adding the cicada slough liquid medicine and the mixed liquid medicine into the modified salvia miltiorrhiza, adding maltose and the chrysanthemum extract according to the proportion, uniformly mixing, and processing and forming to obtain the health-care product. The health-care product can relieve insomnia.
Example 2
A preparation method of a health-care product comprises the following steps: firstly, preparing raw materials, wherein the raw materials comprise: 4g of cicada slough, 7g of astragalus membranaceus, 6g of lucid ganoderma, 4g of mantis egg-case, 2g of spina date seeds, 5g of pearl powder, 5g of ginseng, 4g of pseudo-ginseng, 11g of maltose, 4.5g of chrysanthemum extract and 4g of modified salvia miltiorrhiza, and the raw materials are cleaned and subjected to impurity removal for later use; then, ootheca mantidis is processed: removing impurities from the collected ootheca Mantidis, and sterilizing by ultrasonic waves; putting clean ootheca Mantidis on a food steamer, steaming with slow fire for 4h until worm eggs die; placing the boiled ootheca Mantidis in the sun to dry for 2.5 days until the ootheca Mantidis is completely dry; cutting into pieces for later use; then, preparing modified salvia miltiorrhiza: cleaning Saviae Miltiorrhizae radix, air drying, slicing to obtain Saviae Miltiorrhizae radix slice, soaking in 90% ethanol for 8min, taking out, and air drying; putting the treated salvia miltiorrhiza slices into a reaction vat, adding purified water and methanol, then adding citric acid, adding alkali to adjust the pH value to 9, and carrying out decoction reflux extraction; cooling the extracted decoction, adding acid to adjust pH to 2, standing at room temperature for 13h, filtering, mixing filtrates, and concentrating under reduced pressure to obtain mixed solution; removing impurities from the mixed solution to obtain a salvia miltiorrhiza decoction, and concentrating the salvia miltiorrhiza decoction by a low-temperature membrane to obtain modified salvia miltiorrhiza; next, cicada slough is processed: taking periostracum Cicadae according to a ratio, cleaning and crushing the periostracum Cicadae for later use, using rice washing water of polished round-grained rice, filtering rice grains, taking out the rice washing water, adding the rice washing water and the periostracum Cicadae powder into a medicine pot according to a weight ratio of 10:1, decocting for 10min with strong fire, turning to mild fire for decocting for 6h after water is boiled, and filtering out medicine liquid for later use; next, adding the astragalus, the lucid ganoderma, the mantis egg-case, the spina date seed, the pearl powder, the ginseng and the pseudo-ginseng into a reaction vat according to the proportion, adding water, stirring and heating, stopping heating when the temperature is raised to 120 ℃, stopping heating after 4 hours, cooling at normal temperature, and filtering out mixed medicine juice for later use; and finally, uniformly stirring the cicada slough liquid medicine and the mixed liquid medicine, adding the cicada slough liquid medicine and the mixed liquid medicine into the modified salvia miltiorrhiza, adding maltose and the chrysanthemum extract according to the proportion, uniformly mixing, and processing and forming.
The health-care product can relieve insomnia.
Example 3
A preparation method of a health-care product comprises the following steps: firstly, preparing raw materials, wherein the raw materials comprise: 6g of cicada slough, 13g of astragalus membranaceus, 9g of lucid ganoderma, 6g of mantis egg-case, 4g of spina date seed, 7g of pearl powder, 13g of ginseng, 8g of pseudo-ginseng, 14g of maltose, 5.5g of chrysanthemum extract and 7g of modified salvia miltiorrhiza, and the raw materials are cleaned and subjected to impurity removal for later use; then, ootheca mantidis is processed: removing impurities from the collected ootheca Mantidis, and sterilizing by ultrasonic waves; putting clean ootheca Mantidis on a food steamer, steaming with slow fire for 5h until worm eggs die; placing the boiled ootheca Mantidis in the sun to dry for 3d until the ootheca Mantidis is completely dry; cutting into pieces for later use; then, preparing modified salvia miltiorrhiza: cleaning Saviae Miltiorrhizae radix, air drying, slicing to obtain Saviae Miltiorrhizae radix slice, soaking in 90% ethanol for 10min, taking out, and air drying; putting the treated salvia miltiorrhiza slices into a reaction vat, adding purified water and methanol, then adding citric acid, adding alkali to adjust the pH value to 10, and carrying out decoction reflux extraction; cooling the extracted decoction, adding acid to adjust pH to 3, standing at room temperature for 15h, filtering, mixing filtrates, and concentrating under reduced pressure to obtain mixed solution; removing impurities from the mixed solution to obtain a salvia miltiorrhiza decoction, and concentrating the salvia miltiorrhiza decoction by a low-temperature membrane to obtain modified salvia miltiorrhiza; next, cicada slough is processed: taking periostracum Cicadae according to a ratio, cleaning and crushing the periostracum Cicadae for later use, using rice washing water of polished round-grained rice, filtering rice grains, taking out the rice washing water, adding the rice washing water and the periostracum Cicadae powder into a medicine pot according to a weight ratio of 10:1, decocting for 15min with strong fire, turning to mild fire for decocting for 7h after water is boiled, and filtering out medicine liquid for later use; next, adding the astragalus, the lucid ganoderma, the mantis egg-case, the spina date seed, the pearl powder, the ginseng and the pseudo-ginseng into a reaction vat according to the proportion, adding water, stirring and heating, stopping heating when the temperature is raised to 130 ℃, stopping heating after 6 hours, cooling at normal temperature, and filtering out mixed medicine juice for later use; and finally, uniformly stirring the cicada slough liquid medicine and the mixed liquid medicine, adding the cicada slough liquid medicine and the mixed liquid medicine into the modified salvia miltiorrhiza, adding maltose and the chrysanthemum extract according to the proportion, uniformly mixing, and processing and forming.
The health-care product can relieve insomnia.
Example 4
A preparation method of a health-care product comprises the following steps: firstly, preparing raw materials, wherein the raw materials comprise: 5g of cicada slough, 9g of astragalus membranaceus, 7g of lucid ganoderma, 5g of mantis egg-case, 3g of spina date seeds, 6g of pearl powder, 7g of ginseng, 5g of pseudo-ginseng, 12g of maltose, 5g of chrysanthemum extract and 6g of modified salvia miltiorrhiza, and the raw materials are cleaned and subjected to impurity removal for later use; then, ootheca mantidis is processed: removing impurities from the collected ootheca Mantidis, and sterilizing by ultrasonic waves; putting clean ootheca Mantidis on a food steamer, steaming with slow fire for 4h until worm eggs die; placing the boiled ootheca Mantidis in the sun to dry for 2.5 days until the ootheca Mantidis is completely dry; cutting into pieces for later use; then, preparing modified salvia miltiorrhiza: cleaning Saviae Miltiorrhizae radix, air drying, slicing to obtain Saviae Miltiorrhizae radix slice, soaking in 90% ethanol for 8min, taking out, and air drying; putting the treated salvia miltiorrhiza slices into a reaction vat, adding purified water and methanol, then adding citric acid, adding alkali to adjust the pH value to 9, and carrying out decoction reflux extraction; cooling the extracted decoction, adding acid to adjust pH to 2, standing at room temperature for 13h, filtering, mixing filtrates, and concentrating under reduced pressure to obtain mixed solution; removing impurities from the mixed solution to obtain a salvia miltiorrhiza decoction, and concentrating the salvia miltiorrhiza decoction by a low-temperature membrane to obtain modified salvia miltiorrhiza; next, cicada slough is processed: taking periostracum Cicadae according to a ratio, cleaning and crushing the periostracum Cicadae for later use, using rice washing water of polished round-grained rice, filtering rice grains, taking out the rice washing water, adding the rice washing water and the periostracum Cicadae powder into a medicine pot according to a weight ratio of 10:1, decocting for 10min with strong fire, turning to mild fire for decocting for 6h after water is boiled, and filtering out medicine liquid for later use; next, adding the astragalus, the lucid ganoderma, the mantis egg-case, the spina date seed, the pearl powder, the ginseng and the pseudo-ginseng into a reaction vat according to the proportion, adding water, stirring and heating, stopping heating when the temperature is raised to 120 ℃, stopping heating after 5 hours, cooling at normal temperature, and filtering out mixed medicine juice for later use; and finally, uniformly stirring the cicada slough liquid medicine and the mixed liquid medicine, adding the cicada slough liquid medicine and the mixed liquid medicine into the modified salvia miltiorrhiza, adding maltose and the chrysanthemum extract according to the proportion, uniformly mixing, and processing and forming.
The health-care product can relieve insomnia.
Example 5
A preparation method of a health-care product comprises the following steps: firstly, preparing raw materials, wherein the raw materials comprise: 5g of cicada slough, 11g of astragalus membranaceus, 8g of lucid ganoderma, 5g of mantis egg-case, 3g of spina date seeds, 6g of pearl powder, 11g of ginseng, 7g of pseudo-ginseng, 13g of maltose, 5g of chrysanthemum extract and 6g of modified salvia miltiorrhiza, and the raw materials are cleaned and subjected to impurity removal for later use; then, ootheca mantidis is processed: removing impurities from the collected ootheca Mantidis, and sterilizing by ultrasonic waves; putting clean ootheca Mantidis on a food steamer, steaming with slow fire for 4h until worm eggs die; placing the boiled ootheca Mantidis in the sun to dry for 2.5 days until the ootheca Mantidis is completely dry; cutting into pieces for later use; then, preparing modified salvia miltiorrhiza: cleaning Saviae Miltiorrhizae radix, air drying, slicing to obtain Saviae Miltiorrhizae radix slice, soaking in 90% ethanol for 8min, taking out, and air drying; putting the treated salvia miltiorrhiza slices into a reaction vat, adding purified water and methanol, then adding citric acid, adding alkali to adjust the pH value to 9, and carrying out decoction reflux extraction; cooling the extracted decoction, adding acid to adjust pH to 2, standing at room temperature for 13h, filtering, mixing filtrates, and concentrating under reduced pressure to obtain mixed solution; removing impurities from the mixed solution to obtain a salvia miltiorrhiza decoction, and concentrating the salvia miltiorrhiza decoction by a low-temperature membrane to obtain modified salvia miltiorrhiza; next, cicada slough is processed: taking periostracum Cicadae according to a ratio, cleaning and crushing the periostracum Cicadae for later use, using rice washing water of polished round-grained rice, filtering rice grains, taking out the rice washing water, adding the rice washing water and the periostracum Cicadae powder into a medicine pot according to a weight ratio of 10:1, decocting for 10min with strong fire, turning to mild fire for decocting for 6h after water is boiled, and filtering out medicine liquid for later use; next, adding the astragalus, the lucid ganoderma, the mantis egg-case, the spina date seed, the pearl powder, the ginseng and the pseudo-ginseng into a reaction vat according to the proportion, adding water, stirring and heating, stopping heating when the temperature is raised to 120 ℃, stopping heating after 5 hours, cooling at normal temperature, and filtering out mixed medicine juice for later use; and finally, uniformly stirring the cicada slough liquid medicine and the mixed liquid medicine, adding the cicada slough liquid medicine and the mixed liquid medicine into the modified salvia miltiorrhiza, adding maltose and the chrysanthemum extract according to the proportion, uniformly mixing, and processing and forming.
The health-care product can relieve insomnia.
Example 6
A preparation method of a health-care product comprises the following steps: firstly, preparing raw materials, wherein the raw materials comprise: 3g of cicada slough, 5g of astragalus membranaceus, 5g of lucid ganoderma, 3g of mantis egg-case, 1g of spina date seed, 4g of pearl powder, 3g of ginseng, 3g of pseudo-ginseng, 10g of maltose, 4g of chrysanthemum extract and 3g of modified salvia miltiorrhiza, and the raw materials are cleaned and subjected to impurity removal for later use; then, ootheca mantidis is processed: removing impurities from the collected ootheca Mantidis, and sterilizing by ultrasonic waves; putting clean ootheca Mantidis on a food steamer, steaming with slow fire for 4h until worm eggs die; placing the boiled ootheca Mantidis in the sun to dry for 2.5 days until the ootheca Mantidis is completely dry; cutting into pieces for later use; then, preparing modified salvia miltiorrhiza: cleaning Saviae Miltiorrhizae radix, air drying, slicing to obtain Saviae Miltiorrhizae radix slice, soaking in 90% ethanol for 8min, taking out, and air drying; putting the treated salvia miltiorrhiza slices into a reaction vat, adding purified water and methanol, then adding citric acid, adding alkali to adjust the pH value to 9, and carrying out decoction reflux extraction; cooling the extracted decoction, adding acid to adjust pH to 2, standing at room temperature for 13h, filtering, mixing filtrates, and concentrating under reduced pressure to obtain mixed solution; removing impurities from the mixed solution to obtain a salvia miltiorrhiza decoction, and concentrating the salvia miltiorrhiza decoction by a low-temperature membrane to obtain modified salvia miltiorrhiza; next, cicada slough is processed: taking periostracum Cicadae according to a ratio, cleaning and crushing the periostracum Cicadae for later use, using rice washing water of polished round-grained rice, filtering rice grains, taking out the rice washing water, adding the rice washing water and the periostracum Cicadae powder into a medicine pot according to a weight ratio of 10:1, decocting for 10min with strong fire, turning to mild fire for decocting for 6h after water is boiled, and filtering out medicine liquid for later use; next, adding the astragalus, the lucid ganoderma, the mantis egg-case, the spina date seed, the pearl powder, the ginseng and the pseudo-ginseng into a reaction vat according to the proportion, adding water, stirring and heating, stopping heating when the temperature is raised to 120 ℃, stopping heating after 4 hours, cooling at normal temperature, and filtering out mixed medicine juice for later use; and finally, uniformly stirring the cicada slough liquid medicine and the mixed liquid medicine, adding the cicada slough liquid medicine and the mixed liquid medicine into the modified salvia miltiorrhiza, adding maltose and the chrysanthemum extract according to the proportion, uniformly mixing, and processing and forming.
The health-care product can relieve insomnia.
Example 7
A preparation method of a health-care product comprises the following steps: firstly, preparing raw materials, wherein the raw materials comprise: 7g of cicada slough, 15g of astragalus membranaceus, 10g of lucid ganoderma, 7g of mantis egg-case, 5g of spina date seed, 8g of pearl powder, 15g of ginseng, 9g of pseudo-ginseng, 15g of maltose, 6g of chrysanthemum extract and 8g of modified salvia miltiorrhiza, and the raw materials are cleaned and subjected to impurity removal for later use; then, ootheca mantidis is processed: removing impurities from the collected ootheca Mantidis, and sterilizing by ultrasonic waves; putting clean ootheca Mantidis on a food steamer, steaming with slow fire for 4h until worm eggs die; placing the boiled ootheca Mantidis in the sun to dry for 2-3d until completely dry; cutting into pieces for later use; then, preparing modified salvia miltiorrhiza: cleaning Saviae Miltiorrhizae radix, air drying, slicing to obtain Saviae Miltiorrhizae radix slice, soaking in 90% ethanol for 8min, taking out, and air drying; putting the treated salvia miltiorrhiza slices into a reaction vat, adding purified water and methanol, then adding citric acid, adding alkali to adjust the pH value to 9, and carrying out decoction reflux extraction; cooling the extracted decoction, adding acid to adjust pH to 2, standing at room temperature for 13h, filtering, mixing filtrates, and concentrating under reduced pressure to obtain mixed solution; removing impurities from the mixed solution to obtain a salvia miltiorrhiza decoction, and concentrating the salvia miltiorrhiza decoction by a low-temperature membrane to obtain modified salvia miltiorrhiza; next, cicada slough is processed: taking periostracum Cicadae according to a ratio, cleaning and crushing the periostracum Cicadae for later use, using rice washing water of polished round-grained rice, filtering rice grains, taking out the rice washing water, adding the rice washing water and the periostracum Cicadae powder into a medicine pot according to a weight ratio of 10:1, decocting for 10min with strong fire, turning to mild fire for decocting for 6h after water is boiled, and filtering out medicine liquid for later use; next, adding the astragalus, the lucid ganoderma, the mantis egg-case, the spina date seed, the pearl powder, the ginseng and the pseudo-ginseng into a reaction vat according to the proportion, adding water, stirring and heating, stopping heating when the temperature is raised to 120 ℃, stopping heating after 4 hours, cooling at normal temperature, and filtering out mixed medicine juice for later use; and finally, uniformly stirring the cicada slough liquid medicine and the mixed liquid medicine, adding the cicada slough liquid medicine and the mixed liquid medicine into the modified salvia miltiorrhiza, adding maltose and the chrysanthemum extract according to the proportion, uniformly mixing, and processing and forming.
The health-care product can relieve insomnia.
Comparative example 1
Firstly, preparing raw materials, wherein the raw materials comprise: 15g of astragalus membranaceus, 10g of lucid ganoderma, 7g of mantis egg-case, 5g of spina date seed, 8g of pearl powder, 15g of ginseng, 9g of pseudo-ginseng, 15g of maltose, 6g of chrysanthemum extract and 8g of modified salvia miltiorrhiza, and the raw materials are cleaned and subjected to impurity removal for later use; then, ootheca mantidis is processed: removing impurities from the collected ootheca Mantidis, and sterilizing by ultrasonic waves; putting clean ootheca Mantidis on a food steamer, steaming with slow fire for 4h until worm eggs die; placing the boiled ootheca Mantidis in the sun to dry for 2.5 days until the ootheca Mantidis is completely dry; cutting into pieces for later use; then, preparing modified salvia miltiorrhiza: cleaning Saviae Miltiorrhizae radix, air drying, slicing to obtain Saviae Miltiorrhizae radix slice, soaking in 90% ethanol for 8min, taking out, and air drying; putting the treated salvia miltiorrhiza slices into a reaction vat, adding purified water and methanol, then adding citric acid, adding alkali to adjust the pH value to 9, and carrying out decoction reflux extraction; cooling the extracted decoction, adding acid to adjust pH to 2, standing at room temperature for 13h, filtering, mixing filtrates, and concentrating under reduced pressure to obtain mixed solution; removing impurities from the mixed solution to obtain a salvia miltiorrhiza decoction, and concentrating the salvia miltiorrhiza decoction by a low-temperature membrane to obtain modified salvia miltiorrhiza; next, adding the astragalus, the lucid ganoderma, the mantis egg-case, the spina date seed, the pearl powder, the ginseng and the pseudo-ginseng into a reaction vat according to the proportion, adding water, stirring and heating, stopping heating when the temperature is raised to 120 ℃, stopping heating after 4 hours, cooling at normal temperature, and filtering out mixed medicine juice for later use; and finally, uniformly stirring the mixed medicine juice, adding the mixed medicine juice into the modified salvia miltiorrhiza, adding maltose and the chrysanthemum extract according to the proportion, uniformly mixing, and processing and forming.
Comparative example 2
A preparation method of a health-care product comprises the following steps: firstly, preparing raw materials, wherein the raw materials comprise: 7g of cicada slough, 15g of astragalus membranaceus, 10g of lucid ganoderma, 7g of mantis egg-case, 5g of spina date seed, 8g of pearl powder, 15g of ginseng, 9g of pseudo-ginseng, 15g of maltose, 6g of chrysanthemum extract and 8g of salvia miltiorrhiza, and the raw materials are cleaned and subjected to impurity removal for later use; then, ootheca mantidis is processed: removing impurities from the collected ootheca Mantidis, and sterilizing by ultrasonic waves; putting clean ootheca Mantidis on a food steamer, steaming with slow fire for 4h until worm eggs die; placing the boiled ootheca Mantidis in the sun to dry for 2.5 days until the ootheca Mantidis is completely dry; cutting into pieces for later use; then, preparing modified salvia miltiorrhiza: cleaning Saviae Miltiorrhizae radix, air drying, slicing to obtain Saviae Miltiorrhizae radix slice, soaking in 90% ethanol for 8min, taking out, and air drying; slicing Saviae Miltiorrhizae radix, decocting, removing impurities to obtain Saviae Miltiorrhizae radix decoction, and concentrating the Saviae Miltiorrhizae radix decoction with low temperature membrane to obtain modified Saviae Miltiorrhizae radix; next, cicada slough is processed: taking periostracum Cicadae according to a ratio, cleaning and crushing the periostracum Cicadae for later use, using rice washing water of polished round-grained rice, filtering rice grains, taking out the rice washing water, adding the rice washing water and the periostracum Cicadae powder into a medicine pot according to a weight ratio of 10:1, decocting for 10min with strong fire, turning to mild fire for decocting for 6h after water is boiled, and filtering out medicine liquid for later use; next, adding the astragalus, the lucid ganoderma, the mantis egg-case, the spina date seed, the pearl powder, the ginseng and the pseudo-ginseng into a reaction vat according to the proportion, adding water, stirring and heating, stopping heating when the temperature is raised to 120 ℃, stopping heating after 4 hours, cooling at normal temperature, and filtering out mixed medicine juice for later use; and finally, uniformly stirring the cicada slough liquid medicine and the mixed liquid medicine, adding the cicada slough liquid medicine and the mixed liquid medicine into the modified salvia miltiorrhiza, adding maltose and the chrysanthemum extract according to the proportion, uniformly mixing, and processing and forming.
Comparative example 3
A preparation method of a health-care product comprises the following steps: firstly, preparing raw materials, wherein the raw materials comprise: 7g of cicada slough, 15g of astragalus membranaceus, 10g of lucid ganoderma, 7g of mantis egg-case, 5g of spina date seed, 8g of pearl powder, 15g of ginseng, 9g of pseudo-ginseng, 15g of maltose and 6g of chrysanthemum extract, and cleaning the raw materials to remove impurities for later use; then, ootheca mantidis is processed: removing impurities from the collected ootheca Mantidis, and sterilizing by ultrasonic waves; putting clean ootheca Mantidis on a food steamer, steaming with slow fire for 4h until worm eggs die; placing the boiled ootheca Mantidis in the sun to dry for 2.5 days until the ootheca Mantidis is completely dry; cutting into pieces for later use; next, cicada slough is processed: taking periostracum Cicadae according to a ratio, cleaning and crushing the periostracum Cicadae for later use, using rice washing water of polished round-grained rice, filtering rice grains, taking out the rice washing water, adding the rice washing water and the periostracum Cicadae powder into a medicine pot according to a weight ratio of 10:1, decocting for 10min with strong fire, turning to mild fire for decocting for 6h after water is boiled, and filtering out medicine liquid for later use; next, adding the astragalus, the lucid ganoderma, the mantis egg-case, the spina date seed, the pearl powder, the ginseng and the pseudo-ginseng into a reaction vat according to the proportion, adding water, stirring and heating, stopping heating when the temperature is raised to 120 ℃, stopping heating after 4 hours, cooling at normal temperature, and filtering out mixed medicine juice for later use; and finally, uniformly stirring the cicada slough liquid medicine and the mixed liquid medicine, adding the cicada slough liquid medicine and the mixed liquid medicine into the modified salvia miltiorrhiza, adding maltose and the chrysanthemum extract according to the proportion, uniformly mixing, and processing and forming.
Comparative example 4
A preparation method of a health-care product comprises the following steps: firstly, preparing raw materials, wherein the raw materials comprise: 7g of cicada slough, 15g of astragalus membranaceus, 10g of lucid ganoderma, 7g of mantis egg-case, 8g of pearl powder, 15g of ginseng, 9g of pseudo-ginseng, 15g of maltose, 6g of chrysanthemum extract and 8g of modified salvia miltiorrhiza, and the raw materials are cleaned and subjected to impurity removal for later use; then, ootheca mantidis is processed: removing impurities from the collected ootheca Mantidis, and sterilizing by ultrasonic waves; putting clean ootheca Mantidis on a food steamer, steaming with slow fire for 4h until worm eggs die; placing the boiled ootheca Mantidis in the sun to dry for 2.5 days until the ootheca Mantidis is completely dry; cutting into pieces for later use; then, preparing the salvia miltiorrhiza paste: cleaning Saviae Miltiorrhizae radix, air drying, slicing to obtain Saviae Miltiorrhizae radix slice, soaking in 90% ethanol for 8min, taking out, and air drying; putting the treated salvia miltiorrhiza slices into a reaction vat, adding purified water and methanol, then adding citric acid, adding alkali to adjust the pH value to 9, and carrying out decoction reflux extraction; cooling the extracted decoction, adding acid to adjust pH to 2, standing at room temperature for 13h, filtering, mixing filtrates, and concentrating under reduced pressure to obtain mixed solution; removing impurities from the mixed solution to obtain a salvia miltiorrhiza decoction, and concentrating the salvia miltiorrhiza decoction by a low-temperature membrane to obtain modified salvia miltiorrhiza; next, cicada slough is processed: taking periostracum Cicadae according to a ratio, cleaning and crushing the periostracum Cicadae for later use, using rice washing water of polished round-grained rice, filtering rice grains, taking out the rice washing water, adding the rice washing water and the periostracum Cicadae powder into a medicine pot according to a weight ratio of 10:1, decocting for 10min with strong fire, turning to mild fire for decocting for 6h after water is boiled, and filtering out medicine liquid for later use; next, adding the astragalus, the lucid ganoderma, the mantis egg-case, the pearl powder, the ginseng and the pseudo-ginseng into a reaction vat according to the proportion, adding water, stirring and heating, stopping heating when the temperature is raised to 120 ℃, stopping heating after 4 hours, cooling at normal temperature, and filtering out mixed medicine juice for later use; and finally, uniformly stirring the cicada slough liquid medicine and the mixed liquid medicine, adding the cicada slough liquid medicine and the mixed liquid medicine into the modified salvia miltiorrhiza, adding maltose and the chrysanthemum extract according to the proportion, uniformly mixing, and processing and forming.
Randomly selecting 110 insomnia patients, selecting the patients with similar symptoms as much as possible, taking one group of ten patients, taking the health care products of each embodiment and the comparative example for 30 days, respectively detecting the sleep quality before and after the health care products are used for 30 days, and taking the average value of each group to record as follows.
Figure BDA0003153197350000101
Figure BDA0003153197350000111
While the preferred embodiments of the present invention have been described in detail, the present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art.

Claims (8)

1. The formula of the health-care product is characterized by comprising the following components in parts by weight:
3-7 parts of cicada slough, 5-15 parts of astragalus membranaceus, 5-10 parts of lucid ganoderma, 3-7 parts of mantis egg-case, 1-5 parts of spina date seed, 4-8 parts of pearl powder, 3-15 parts of ginseng, 3-9 parts of pseudo-ginseng, 10-15 parts of maltose, 4-6 parts of chrysanthemum extract and 3-8 parts of modified salvia miltiorrhiza.
2. The formula of the health preserving health care product as claimed in claim 1, which is characterized by comprising the following components in parts by weight:
4-6 parts of cicada slough, 7-13 parts of astragalus membranaceus, 6-9 parts of lucid ganoderma, 4-6 parts of mantis egg-case, 2-4 parts of spina date seed, 5-7 parts of pearl powder, 5-13 parts of ginseng, 4-8 parts of pseudo-ginseng, 11-14 parts of maltose, 4.5-5.5 parts of chrysanthemum extract and 4-7 parts of modified salvia miltiorrhiza.
3. The formula of the health preserving health care product as claimed in claim 2, characterized by comprising the following components in parts by weight:
5 parts of cicada slough, 10 parts of astragalus membranaceus, 7 parts of lucid ganoderma, 5 parts of mantis egg-case, 3 parts of spina date seed, 6 parts of pearl powder, 9 parts of ginseng, 6 parts of pseudo-ginseng, 12 parts of maltose, 5 parts of chrysanthemum extract and 6 parts of modified salvia miltiorrhiza.
4. The formula of the health preserving and health care product as claimed in claim 1, wherein the processing method of the periostracum cicada comprises the following steps:
taking the cicada slough according to parts, cleaning and crushing the cicada slough for standby, using rice washing water of polished round-grained rice, filtering rice grains, taking out the rice washing water, adding the rice washing water and the cicada slough powder into a medicine pot according to the weight ratio of 10:1, and decocting to obtain the cicada slough.
5. A formulation of a health preserving and health promoting product as claimed in any one of claims 1 to 3 wherein the preparation method of the modified red sage root comprises the following steps:
s1: cleaning and airing salvia miltiorrhiza, cutting to obtain salvia miltiorrhiza slices, soaking the salvia miltiorrhiza slices in alcohol, taking out and airing for later use;
s2: putting the treated salvia miltiorrhiza slices into a reaction vat, adding purified water and methanol, then adding citric acid, adding alkali to adjust the pH value to 9-10, and carrying out decoction reflux extraction;
s3: cooling the extracted decoction, adding acid to adjust pH, standing at room temperature, filtering, mixing filtrates, and concentrating under reduced pressure to obtain mixed solution;
s4: removing impurities from the mixed solution to obtain a salvia miltiorrhiza decoction, and concentrating the salvia miltiorrhiza decoction by a low-temperature membrane to obtain the modified salvia miltiorrhiza with the relative density of 1.02-1.03.
6. The formula of a health preserving and caring product according to any of claims 1-3, wherein the processing method of ootheca Mantidis comprises the following steps:
s1: removing impurities from the collected ootheca Mantidis, and sterilizing by ultrasonic waves;
s2: putting clean ootheca Mantidis on a food steamer, steaming with slow fire for 2-5h until the insect egg dies;
s3: placing the boiled mantis egg-cases in the sun to dry completely;
s4: cutting into pieces for use.
7. A method for preparing a health preserving health product as claimed in any one of claims 1 to 6 comprising the steps of:
s1: preparing raw materials, cleaning the raw materials and removing impurities for later use;
s2: adding radix astragali, Ganoderma, ootheca Mantidis, semen Ziziphi Spinosae, Margarita powder, Ginseng radix, and Notoginseng radix into reaction jar, adding water, stirring, heating to 110-;
s3: mixing periostracum Cicadae liquid medicine and mixed medicinal liquid, stirring well, adding into modified Saviae Miltiorrhizae radix, adding maltose and flos Chrysanthemi extract according to parts, mixing well, and processing and shaping to obtain the final product.
8. Use of a formulation of a health preserving health product as claimed in any one of claims 1 to 7 in the manufacture of a medicament for relieving insomnia.
CN202110770727.8A 2021-07-08 2021-07-08 Formula, preparation method and application of health-care product Pending CN113440554A (en)

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Citations (3)

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Publication number Priority date Publication date Assignee Title
CN102416071A (en) * 2011-12-06 2012-04-18 常熟雷允上制药有限公司 Medicinal composition with effect of treating insomnia, preparation method and application of medicinal composition
CN105168549A (en) * 2015-10-20 2015-12-23 广西伟健药业有限公司 Health product composition for relieving insomnia or assisting in treatment of insomnia and preparation method thereof
CN106924592A (en) * 2017-03-28 2017-07-07 上海大学 A kind of Chinese medicine preparation for tranquilizing soporific strengthen immunity and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102416071A (en) * 2011-12-06 2012-04-18 常熟雷允上制药有限公司 Medicinal composition with effect of treating insomnia, preparation method and application of medicinal composition
CN105168549A (en) * 2015-10-20 2015-12-23 广西伟健药业有限公司 Health product composition for relieving insomnia or assisting in treatment of insomnia and preparation method thereof
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Application publication date: 20210928