CN113427559B - A nano-fetuin test paper for monitoring diabetic retinopathy and its manufacturing process - Google Patents

Abstract

The invention discloses a process for monitoring diabetic retinopathy by using a nano fetuin test paper, which comprises a fetuin antibody, is used for detecting the fetuin content of serum or other body fluids and is used for monitoring the occurrence and development of diabetic retinopathy. When the preparation device provided by the invention is used, a worker places the prepared nano test paper on a conveyor belt, the conveyor belt is used for transmission, the second air cylinder is started to drive the second cutting knife to vertically cut the nano test paper on the conveyor belt, the conveyor belt is used for continuously driving the nano test paper after the vertical cutting is finished, and the first air cylinder is started to drive the first cutting knife to transversely cut the nano test paper, so that the transverse cutting and the vertical cutting of the nano test paper can be simultaneously carried out, and the production efficiency of the nano test paper is accelerated.

Description

A nano-fetuin test paper for monitoring diabetic retinopathy and its production process

technical field

The invention relates to the technical field of nano-fetuin test paper, in particular to a nano-fetuin test paper for monitoring diabetic retinopathy and a manufacturing process.

Background technique

Diabetic retinopathy is a common chronic complication of diabetes. It belongs to retinal microvascular disease caused by diabetes. In severe cases, it can lead to blindness and seriously affect the quality of life of patients. There are no obvious symptoms in the early stage of diabetic retinopathy. As the course of the disease prolongs, the incidence of diabetic retinopathy increases, and symptoms such as floaters, dark shadows in front of the eyes, blurred vision, visual field defects, and decreased vision may appear. Blinding complications of vitreous hemorrhage and retinal detachment. Diabetic retinopathy is the most common cause of preventable blindness in adults. However, it is not known which diabetic patients may develop diabetic retinopathy and at what stage diabetic retinopathy occurs. It can only be brought to the attention of patients when the clinical symptoms of bleeding have already occurred. In the early stage of diabetic retinopathy, some serum biomarkers have already occurred. Change me, our previous studies have confirmed that fetuin is abnormally high in the serum and intraocular fluid of patients with diabetic retinopathy, and using test strips to detect the occurrence and development of diabetic retinopathy can be regarded as an early warning method.

In the preparation process of the existing diabetic retinopathy nano-test paper, it needs to be cut after the nano-test paper is prepared, and most of the existing nano-test paper cutting devices are cut by a manual cutting machine, and the cutting speed is relatively slow;

Moreover, in the existing automatic nano test paper cutting machine, the stacked test papers cannot be cut, only a single test paper can be cut, and the single cutting speed is relatively slow, which reduces the efficiency of test paper production;

In the cutting process of the existing nano test paper, most of the test paper is cut vertically and then cut horizontally. The vertical cutting and cross cutting are not consistent, and the staff need to change the position of the test paper as a whole before they can cut the test paper. It is troublesome and reduces the cutting efficiency of the test paper.

For this reason, a nano-fetuin test paper for monitoring diabetic retinopathy and its manufacturing process are proposed.

Contents of the invention

The technical task of the present invention is to address the above deficiencies, and provide a nano-fetuin test paper for monitoring diabetic retinopathy and its production process. When the preparation device is used in this scheme, the staff will place the finished test paper on the conveyor belt, and pass the test paper on the conveyor belt. The test paper is continuously transmitted, and at the same time, the second cylinder drives the second cutting knife to cut the test paper vertically, and the first cylinder drives the first cutting knife to cut the test paper horizontally, and the electric push rod cooperates with the baffle to cut the test paper. The test paper is limited, which is convenient for the staff to cut the multi-layer test paper at the same time, and the cutting accuracy is guaranteed by the first infrared ray positioner and the second infrared ray positioner.

Technical scheme of the present invention is realized like this:

A nano-fetuin test paper for monitoring diabetic retinopathy and its production process,

Including nano-fetuin test paper, the nano-fetuin test paper includes two nano-electrode base layers, the outside of the two nano-electrode base layers are bonded with a marking surface layer, and the outside of the two nano-electrode base layers are bonded with Mark the surface layer, the inside of the two nano-electrode base layers is bonded with a blood-conducting layer, the outside of the two nano-electrode base layers is bonded with an enzyme layer, and the outside of one of the nano-electrode base layers is bonded with glue layer, and an anti-adhesive layer is bonded to the outside of the other nano-electrode base layer.

Preferably, the marking surface layer is in the shape of a ring barrel, and the two nano-electrode base layers are pasted inside the marking surface layer.

Preferably, the blood conducting layer is located between the anti-adhesive layer and one of the nano-electrode base layers.

The present invention also proposes a preparation process of nanometer test paper for monitoring diabetic retinopathy, comprising the following steps:

S1. The staff put the finished nano-fetuin test paper on the conveyor belt, and start the conveyor belt at the same time. After the conveyor belt is started, it will drive the production of the nano-fetuin test paper to transmit. During the transmission of the test paper, the staff By starting multiple first infrared locators, the first infrared locators will determine the transmission position of the nano-fetuin test paper, avoiding the wrong transmission position of the nano-fetuin test paper, and at the same time, the activation of the first infrared locator will assist the conveyor belt to After the production is completed, the test paper is transmitted to the designated position to avoid the misalignment of the test paper transmission;

S2. After the conveyor belt transfers the test paper to the designated position, the staff starts the second cylinder. The activation of the second cylinder will drive the mounting plate and the second cutting knife to adjust the up and down positions. The up and down position adjustment of the second cutting knife will The nano-fetuin test paper on the conveyor belt is cut vertically;

S3. After the vertical cutting of the nano-fetuin test paper is completed, the staff continue to start the conveyor belt, which continues to transmit the nano-fetuin test paper, and at the same time start the rodless cylinder to drive the first cylinder and the first cutting knife to adjust the front and rear positions ;

S4. After adjusting the first cylinder and the first cutting knife to the specified position, the staff starts the electric push rod, and the start of the electric push rod will drive the baffle to adjust the position, and the nano tire ball after vertical cutting is completed through the baffle The protein test paper is limited, and the first cutting knife is started after the nano-fetuin test paper is limited, and the first cutting knife is driven by the first cylinder to cross-cut the nano-fetuin test paper.

As a preference, when the rodless cylinder drives the second mounting base and the first cutting knife to move, it will simultaneously drive the second infrared ray positioner located inside the second mounting base to adjust the position, and position the first cutting knife through the second infrared ray positioner The position where the crosscutting is performed to avoid crosscutting errors.

As a preference, when the first infrared locator is used, the position of the first infrared locator can be adjusted by the limit groove and the limit block located inside the shell, and by adjusting the position of the first infrared locator, it can adapt to different nano-fetuin The width and cutting of the test paper.

The present invention also proposes a preparation device for nanometer test paper for monitoring diabetic retinopathy, including: a cutting structure and a limiting structure;

Wherein, the cutting structure is used to cut the test paper horizontally and vertically, and adjust the position of the cutting knife. The cutting structure includes a bottom plate, a casing, a rodless cylinder, a first mounting seat, a first cylinder, a second Mounting seat, first cutting knife, third mounting seat, second cylinder, multiple mounting plates, conveyor belt, threaded through hole, limit plate, bearing, screw rod and second cutting knife, the housing is installed on the On the bottom plate, the rodless cylinder is installed inside the housing, the first mount is fixedly mounted on the slider of the rodless cylinder, and the first cylinder is mounted outside the first mount , the second mounting base is fixedly mounted on the piston rod end of the first cylinder, the first cutting knife is fixedly mounted on the second mounting base, and the third mounting base is fixedly mounted on the Inside the shell, the second cylinder is mounted on the outside of the third mounting base, the mounting plate is fixedly mounted on the end of the piston rod of the second cylinder, and a plurality of threaded through holes are opened in the Inside the mounting plate, the conveyor belt is installed on the bottom plate, the screw rod is movably connected to the inside of the threaded through hole, the screw rod is movably connected to the limiting plate, and the second cutting knife is installed on the limiting plate;

Wherein, the limit structure is used to limit the nano-fetuin test paper in the cutting process, and avoid errors in the cutting position of the cutter. The limit structure includes an electric push rod, a baffle, A plurality of first infrared locators, a limiting slot, a limiting block and a plurality of second infrared locators, the limiting slot is set inside the housing, and the limiting block is movably connected to the limiting slot The first infrared locator is fixedly installed outside the limiting slot, and the second infrared locator is installed inside the second mounting base.

Preferably, the threaded connection between the screw rod and the threaded through hole.

Preferably, the limiting plate and the screw are rotatably connected through a bearing.

Preferably, there is a sliding connection between the limiting groove and the limiting block.

Compared with prior art, advantage and positive effect of the present invention are:

1. When the preparation device provided by the present invention is in use, the staff will place the prepared nano-test paper on the conveyor belt, drive it through the conveyor belt, and drive the second cutting knife to vertically cut the nano-test paper on the conveyor belt by starting the second cylinder After the vertical cutting is completed, continue to drive the nano-test paper through the conveyor belt, and drive the first cutting knife to cut the nano-test paper by starting the first cylinder, so that the cross-cutting and vertical cutting of the nano-test paper can be carried out at the same time, speeding up the nano-test paper. Productivity;

2, when the preparation device provided by the present invention is used, in the process of cutting the nano test paper, the staff can avoid the transmission error of the conveyor belt to the nano test paper by starting the first infrared ray locator, and the setting of the first infrared ray locator. By starting the rodless cylinder, the start of the rodless cylinder can drive the second mounting seat and the second infrared ray positioner to adjust the position. The position adjustment of the second infrared ray positioner will position the cutting position of the first cutting knife. Avoid cropping errors;

3. In the present invention, the two nano-electrode base layers are bonded through the marking surface layer, and blood-conducting layers are respectively set in the two nano-electrode base layers. It is separated from the anti-adhesive layer, so that a new blood glucose test paper can be formed between the two nano-electrode base layers, and a second test can be performed, which is convenient for users to use and reduces the waste of test paper.

Description of drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the accompanying drawings required in the embodiments. Obviously, the accompanying drawings in the following description are only some of the present invention. Embodiments, for those of ordinary skill in the art, other drawings can also be obtained based on these drawings without any creative effort.

Fig. 1 is a schematic diagram of the preparation process of nano-test paper for monitoring diabetic retinopathy according to an embodiment of the present invention;

Fig. 2 is a schematic structural view of a nano-test paper preparation device for monitoring diabetic retinopathy according to the present invention;

Fig. 3 is one of the cross-sectional structural schematic diagrams of the nano-test paper preparation device for monitoring diabetic retinopathy according to the present invention;

Fig. 4 is a structural schematic diagram of another viewing angle of a nano-test paper preparation device for monitoring diabetic retinopathy according to the present invention;

Fig. 5 is a schematic diagram of the enlarged structure of area A in Fig. 2;

Fig. 6 is a schematic structural view of a screw and a limiting plate in a nano-test paper preparation device for monitoring diabetic retinopathy according to the present invention;

Fig. 7 is a structural schematic diagram of a mounting plate and a threaded through hole in a nano-test paper preparation device for monitoring diabetic retinopathy according to the present invention;

Fig. 8 is a schematic structural diagram of a nano-test paper for monitoring diabetic retinopathy according to an embodiment of the present invention;

Fig. 9 is a schematic diagram of a side-view structure of a nano-test paper for monitoring diabetic retinopathy according to an embodiment of the present invention;

Fig. 10 is the second schematic diagram of the cross-sectional structure of the nano-test paper preparation device for monitoring diabetic retinopathy according to the present invention;

Fig. 11 is a side-view structure schematic diagram of a nano-test paper preparation device for monitoring diabetic retinopathy according to the present invention;

Fig. 12 is the third schematic diagram of the cross-sectional structure of the nano-test paper preparation device for monitoring diabetic retinopathy according to the present invention.

In the picture:

1. Cutting structure; 10. Bottom plate; 11. Shell; 12. Rodless cylinder; 13. First mounting seat; 14. First cylinder; 15. Second mounting seat; 16. First cutting knife; 17. The third mounting seat; 18, the second cylinder; 19, the mounting plate; 101, the conveyor belt; 102, the threaded through hole; 103, the limit plate; 104, the bearing; 105, the screw rod; 106, the second cutting knife;

2. Limiting structure; 20. Electric push rod; 21. Baffle; 22. First infrared locator; 23. Limiting slot; 24. Limiting block; 25. Second infrared locator;

3. Nano-fetuin test paper; 31. Nano-electrode base layer; 32. Logo surface layer; 33. Blood-conducting layer; 34. Enzyme layer; 35. Adhesive layer; 36. Anti-adhesive layer.

Detailed ways

In order to more clearly understand the above objects, features and advantages of the present invention, the present invention will be further described below in conjunction with the accompanying drawings and embodiments. It should be noted that, in the case of no conflict, the embodiments of the present application and the features in the embodiments can be combined with each other.

The present invention will be further described below in conjunction with the accompanying drawings and specific embodiments.

Example 1

As shown in Figure 1, the present invention also provides a kind of preparation technology of the nano test paper of monitoring diabetic retinopathy, comprises the following steps:

S1. The staff places the nano-fetuin test paper 3 after production on the conveyor belt 101, and starts the conveyor belt 101 at the same time. After the conveyor belt 101 is started, it will drive the nano-fetuin test paper 3 after production to be transmitted, and the test paper is transmitted. During the process, the staff starts a plurality of first infrared locators 22, and the first infrared locators 22 will determine the transmission position of the nano-fetuin test paper 3 to avoid errors in the transmission position of the nano-fetuin test paper 3. At the same time, the first The activation of the infrared positioner 22 will assist the conveyor belt 101 to transfer the test paper after production to the designated position, so as to avoid the misalignment of the test paper transmission;

S2. After the conveyor belt 101 transmits the test paper to the designated position, the staff starts the second air cylinder 18, and the start of the second air cylinder 18 will drive the mounting plate 19 and the second cutting knife 106 to adjust the upper and lower positions. The up and down position adjustment will vertically cut the nano-fetuin test paper 3 on the conveyor belt 101;

S3. After the vertical cutting of the nano-fetuin test paper 3 is completed, the staff continues to start the conveyor belt 101, and the conveyor belt 101 continues to transmit the nano-fetuin test paper 3. At the same time, the rodless cylinder 12 is started to drive the first cylinder 14 and the first cutting machine. The cutter 16 is adjusted in front and rear position;

S4. After adjusting the first cylinder 14 and the first cutting knife 16 to the specified position, the staff starts the electric push rod 20, and the start of the electric push rod 20 will drive the baffle 21 to adjust the position, and the vertical cutting through the baffle 21 After the completion of the nano-fetuin test paper 3, the limit is carried out, and the first cutting knife 16 is started after the completion of the limit of the nano-fetuin test paper 3, and the first cutting knife 16 is driven by the first cylinder 14 to the nano-fetuin test paper. Test paper 3 was cross-cut.

Specifically, when the rodless cylinder 12 drives the second mounting base 15 and the first cutting knife 16 to move, it will simultaneously drive the second infrared ray positioner 25 inside the second mounting base 15 to adjust the position. Locate the position where the first cutting knife 16 performs cross-cutting, so as to avoid cross-cutting errors;

By adopting the above technical solution, the position of the second infrared locator 25 can be adjusted driven by the rodless cylinder 12, and the position of the test paper transmission can be monitored in real time by adjusting the position of the second infrared locator 25.

Specifically, when the first infrared locator 22 is in use, the position of the first infrared locator 22 can be adjusted by the limit groove 23 and the limit block 24 inside the casing 11, and by adjusting the position of the first infrared locator 22, Adapt to the width and narrowness cutting conditions of different nano-fetuin test papers 3 .

Example 2

As shown in Figures 1 to 6, a preparation device for monitoring nano-test paper for diabetic retinopathy according to an embodiment of the present invention includes: a cutting structure 1 and a limiting structure 2;

Among them, the cutting structure 1 is used to cut the test paper horizontally and vertically, and adjust the position of the cutter. The cutting structure 1 includes a bottom plate 10, a casing 11, a rodless cylinder 12, a first mounting seat 13, and a first cylinder 14. , the second mounting seat 15, the first cutting knife 16, the third mounting seat 17, the second cylinder 18, a plurality of mounting plates 19, conveyor belt 101, threaded through hole 102, limit plate 103, bearing 104, screw rod 105 and The second cutting knife 106, the housing 11 is installed on the base plate 10, the rodless cylinder 12 is installed in the inside of the housing 11, the first mounting base 13 is fixedly installed on the slider of the rodless cylinder 12, and the first cylinder 14 is installed on the second The outside of a mounting base 13, the second mounting base 15 is fixedly mounted on the end of the piston rod of the first cylinder 14, the first cutting knife 16 is fixedly mounted on the second mounting base 15, and the third mounting base 17 is fixedly mounted on the shell 11, the second cylinder 18 is installed on the outside of the third mounting seat 17, and the mounting plate 19 is fixedly mounted on the piston rod end of the second cylinder 18. A plurality of threaded through holes 102 are all opened in the inside of the mounting plate 19, and the conveyor belt 101 is installed on the bottom plate 10, the screw rod 105 is movably connected to the internal screw rod 105 of the threaded through hole 102 and is movably connected to the limiting plate 103, and the second cutting knife 106 is installed on the limiting plate 103;

Among them, the limit structure 2 is used to limit the nano-fetuin test paper 3 in the cutting process, and to avoid errors in the cutting position of the cutter. The limit structure 2 includes an electric push rod 20, a baffle 21, multiple A first infrared locator 22, a limit groove 23, a limit block 24 and a plurality of second infrared locators 25, the limit groove 23 is opened in the inside of the shell 11, and the limit block 24 is movably connected to the limit groove 23. Inside, the first infrared locator 22 is fixedly installed outside the limiting groove 23, and the second infrared locator 25 is installed inside the second mounting base 15;

By adopting the above-mentioned technical scheme, when this scheme is used, the staff place the finished test paper on the conveyor belt 101, and start the conveyor belt 101, the startup of the conveyor belt 101 will drive the nano-fetuin test paper 3 to transmit, and at the same time, the staff The first infrared locator 22 can be turned on, and the start of the first infrared locator 22 will locate the nano-test paper being transmitted, so as to avoid the error of the test paper transmission position. After the nano-test paper is transferred to the designated position, the staff can start the second cylinder 18 , the start of the second cylinder 18 will drive the mounting plate 19 and the second cutting knife 106 to adjust the position up and down, so as to cut the test paper. Installed to the positions of different threaded through holes 102, thereby the installation position of the second cutting knife 106 is adjusted to adapt to more cutting situations. After the vertical cutting of test paper is completed, the staff can continue to start the conveyor belt 101, and the The test paper after cutting is pushed forward, and the test paper is limited by starting the electric push rod 20 to drive the baffle plate 21, and the rodless cylinder 12 is started to drive the first mounting seat 13 to adjust the front and rear positions. The starting of the first mounting seat 13 will Drive the first cylinder 14 and the first cutting knife 16 to adjust the position, start the first cylinder 14 to drive the first cutting knife 16 to cross-cut the test paper, so as to continuously cut the nano-test paper, so that the cross-cut and vertical cut It can be completed at the same time, and by means of the first cylinder 14 and the second cylinder 18, the staff can cut more nanometer test papers at one time.

Specifically, the threaded connection between the screw rod 105 and the threaded through hole 102 .

By adopting the above technical solution, the threaded connection between the screw rod 105 and the threaded through hole 102 facilitates the staff to install the second cutting knife 106 on the mounting plate 19 through the screw rod 105 .

Specifically, the limiting plate 103 and the screw 105 are rotationally connected through a bearing 104 .

By adopting the above technical solution, the rotational connection between the limiting plate 103 and the screw rod 105 facilitates the staff to thread the screw rod 105 into the threaded through hole 102 through the bearing 104 .

Specifically, there is a sliding connection between the limiting groove 23 and the limiting block 24 .

By adopting the above technical solution, the limiting block 24 is slidably connected to the inside of the limiting groove 23 , provides a moving track for the limiting block 24 through the limiting groove 23 , and simultaneously limits and fixes the limiting block 24 through the limiting groove 23 .

Example 3

As shown in Figures 8-9, the difference between this embodiment and Example 1 is that the present invention also provides a nano-test paper for monitoring diabetic retinopathy, including nano-fetuin test paper 3, nano-fetuin test paper 3 includes two nano-electrode base layers 31, the outside of the two nano-electrode base layers 31 are bonded with a marking surface layer 32, the outside of the two nano-electrode base layers 31 is bonded with a marking surface layer 32, and the inside of the two nano-electrode base layers 31 Both are bonded with a blood-conducting layer 33, the outside of the two nano-electrode base layers 31 is bonded with an enzyme layer 34, the outside of one nano-electrode base layer 31 is bonded with an adhesive layer 35, and the outside of the other nano-electrode base layer 31 is bonded with an enzyme layer 34. There is an anti-adhesive layer 36;

Adopt above-mentioned technical scheme, mark surface layer 32 is sleeve shape, two nano-electrode base layers 31 are pasted on the inside of mark surface layer 32, the upper half of two nano-electrode base layers 31 are bonded to each other, and off-duty part passes adhesive layer 35 Bonded together with the anti-adhesive layer 36, the adhesive layer 35 is a water-based adsorption layer, which can be adsorbed with the anti-adhesive layer 36, but does not have stickiness. During use, the blood is collected through the blood-conducting layer 33, and passed through two nanometers. The electrode base layer 31 and the enzyme layer 34 enhance the monitoring effect, and at the same time, when the measurement effect is not ideal, the lower half of the two nano-electrode base layers 31 can be separated for separate testing, saving the waste of test paper.

In order to facilitate the understanding of the above-mentioned technical solution of the present invention, the working principle or operation mode of the present invention in the actual process will be described in detail below.

In actual application, the staff place the finished test paper on the conveyor belt 101 and start the conveyor belt 101. The start of the conveyor belt 101 will drive the nano-fetuin test paper 3 to be transmitted, and at the same time the staff can turn on the first infrared positioning device 22, the start of the first infrared locator 22 will locate the nano-test paper being transmitted, to avoid the error of the test paper transmission position, after the nano-test paper is transmitted to the designated position, the staff can start the second cylinder 18, the second cylinder 18 The start-up will drive the mounting plate 19 and the second cutting knife 106 to adjust the upper and lower positions, thereby cutting the test paper. After the vertical cutting of the test paper is completed, the staff can continue to start the conveyor belt 101 to push the test paper after the vertical cutting. , and by starting the electric push rod 20 to drive the baffle 21 to limit the position of the test paper, after pushing the test paper to the designated position, start the rodless cylinder 12 to drive the first mounting seat 13 to adjust the front and rear positions, and the starting of the first mounting seat 13 will be Drive the first cylinder 14 and the first cutting knife 16 to adjust the position, start the first cylinder 14 to drive the first cutting knife 16 to cross-cut the test paper, so as to continuously cut the nano-test paper, so that the cross-cut and vertical cut It can be completed at the same time, and through the way of the first cylinder 14 and the second cylinder 18, the staff can cut more nanometer test paper at one time. Collect, and strengthen the monitoring effect through the two nano-electrode base layers 31 and the enzyme layer 34. At the same time, when the measurement effect is not satisfactory, the blood-conducting layer 33 of the two nano-electrode base layers 31 can be separated, so that the staff can conduct secondary Take blood for testing and conduct separate tests to save the waste of test paper.

Through the above specific implementation manners, those skilled in the art can easily realize the present invention. However, it should be understood that the present invention is not limited to the specific embodiments described above. On the basis of the disclosed embodiments, those skilled in the technical field can arbitrarily combine different technical features, so as to realize different technical solutions.

Claims (7)

1. A preparation process of nanometer test paper for monitoring diabetic retinopathy, said nanometer test paper for monitoring diabetic retinopathy comprises nano-fetuin antibody test paper (3), and said nano-fetuin antibody test paper (3) comprises two nanometer Electrode base layer (31), the exterior of two described nano-electrode base layers (31) is all bonded with marking surface layer (32), the exterior of two described nano-electrode base layers (31) is bonded with marking surface layer (32) , the insides of the two nano-electrode bases (31) are bonded with a blood-conducting layer (33), the outsides of the two nano-electrode bases (31) are bonded with an enzyme layer (34), and one of the nano-electrodes The exterior of the electrode base layer (31) is bonded with an adhesive layer (35), and the outside of the other nano-electrode base layer (31) is bonded with a release layer (36), and the label surface layer (32) is a ring barrel shape, the two nano-electrode base layers (31) are pasted on the inside of the identification surface layer (32), and the blood-conducting layer (33) is located at the anti-adhesive layer (36) and one of the nano-electrode base layers. between (31); The production of the nanometer test paper for monitoring diabetic retinopathy comprises the following steps: S1. The staff puts the nano-fetuin antibody test strip (3) after production on the conveyor belt (101), and starts the conveyor belt (101) at the same time. After the conveyor belt (101) is started, it will drive the nano-fetuin antibody after production The test paper (3) is transmitted. During the transmission process of the test paper, the staff starts a plurality of first infrared locators (22), and the first infrared locator (22) will detect the position of the nano-fetuin antibody test paper (3). The transmission position is determined to avoid errors in the transmission position of the nano-fetuin antibody test paper (3), and at the same time, the activation of the first infrared locator (22) will assist the conveyor belt 101 to transmit the produced test paper to the designated position to avoid misalignment of the test paper transmission Phenomenon; S2. After the conveyor belt (101) transmits the test paper to the designated position, the staff starts the second cylinder (18), and the activation of the second cylinder (18) will drive the mounting plate (19) and the second cutting knife (106) to move up and down Position adjustment, the up and down position adjustment of the second cutting knife (106) will vertically cut the nano-fetuin antibody test paper (3) on the conveyor belt (101); S3. After the vertical cutting of the nano-fetuin antibody test paper (3) is completed, the staff continues to start the conveyor belt (101), and the conveyor belt (101) continues to transmit the nano-fetuin antibody test paper (3), and at the same time starts the rodless cylinder (12) Drive the first cylinder (14) and the first cutting knife (16) to adjust the front and rear positions; S4. After adjusting the first cylinder (14) and the first cutting knife (16) to the specified position, the staff starts the electric push rod (20), and the start of the electric push rod (20) will drive the baffle (21) to Adjust the position, limit the nano-fetuin antibody test paper (3) after vertical cutting by the baffle plate (21), and start the first cutting knife ( 16), driving the first cutting knife (16) through the first cylinder (14) to cross-cut the nano-fetuin antibody test paper (3). 2. the preparation technology of a kind of nanometer test paper of monitoring diabetic retinopathy according to claim 1 is characterized in that, rodless cylinder (12) drives the second mount (15) and the first cutting knife (16) to move At the same time, it will drive the second infrared locator (25) inside the second mounting base (15) to adjust the position, and the first cutting knife (16) will be positioned at the cross-cutting position by the second infrared locator (25). Avoid cross-cutting errors. 3. the preparation process of a kind of nano test paper for monitoring diabetic retinopathy according to claim 2, is characterized in that, when the first infrared ray positioner (22) uses, be positioned at housing (11) internal limit groove (23) and The limit block (24) can adjust the position of the first infrared locator (22), and by adjusting the position of the first infrared locator (22), it can adapt to the width and narrowness of different nano-fetuin antibody test papers (3). all circumstances. 4. A preparation device for a nano-test paper for monitoring diabetic retinopathy, characterized in that, the nano-test paper for monitoring diabetic retinopathy comprises nano-fetuin antibody test paper (3), and the nano-fetuin antibody test paper (3) Including two nano-electrode base layers (31), the outside of the two nano-electrode base layers (31) are bonded with a marking surface layer (32), and the outside of the two nano-electrode base layers (31) are bonded with a marking surface layer (32), the inside of the two nano-electrode base layers (31) is bonded with a blood-conducting layer (33), and the outside of the two nano-electrode base layers (31) is bonded with an enzyme layer (34), An adhesive layer (35) is bonded to the outside of one of the nano-electrode base layers (31), and a release layer (36) is bonded to the outside of the other nano-electrode base layer (31), and the marking surface layer (32 ) is a ring barrel shape, and the two nano-electrode base layers (31) are pasted on the inside of the label surface layer (32), and the blood-conducting layer (33) is located at the anti-adhesive layer (36) and a between the nano-electrode base layers (31); the preparation device includes: a cutting structure (1) and a limiting structure (2); Wherein, the cutting structure (1) is used to cut the test paper horizontally and vertically, and adjust the position of the cutting knife, and the cutting structure (1) includes a bottom plate (10), a casing (11), a rodless cylinder (12), the first mounting base (13), the first cylinder (14), the second mounting base (15), the first cutting knife (16), the third mounting base (17), the second cylinder (18) , a plurality of mounting plates (19), a conveyor belt (101), a threaded through hole (102), a limiting plate (103), a bearing (104), a screw rod (105) and a second cutting knife (106), the housing (11) is installed on the base plate (10), the rodless cylinder (12) is installed inside the housing (11), and the first mount (13) is fixedly installed on the rodless cylinder ( 12), the first cylinder (14) is mounted on the outside of the first mount (13), and the second mount (15) is fixedly mounted on the first cylinder (14) At the end of the piston rod, the first cutting knife (16) is fixedly installed on the second mounting base (15), and the third mounting base (17) is fixedly installed inside the housing (11), The second cylinder (18) is installed on the outside of the third installation seat (17), the installation plate (19) is fixedly installed on the end of the piston rod of the second cylinder (18), a plurality of the Threaded through holes (102) are all opened in the inside of the mounting plate (19), the conveyor belt (101) is installed on the base plate (10), and the screw rod (105) is movably connected to the threaded through holes ( 102), the screw (105) is movably connected to the limiting plate (103), and the second cutting knife (106) is installed on the limiting plate (103); Wherein, the limiting structure (2) is used to limit the nano-fetuin antibody test paper (3) in the cutting process, and avoid errors in the cutting position of the cutter, and the limiting structure ( 2) Including an electric push rod (20), a baffle (21), a plurality of first infrared locators (22), a limit groove (23), a limit block (24) and a plurality of second infrared locators (25) ), the limiting groove (23) is opened in the inside of the housing (11), the limiting block (24) is movably connected to the inside of the limiting groove (23), and the first infrared locator (22) is fixedly installed on the outside of the limiting groove (23), and the second infrared locator (25) is installed on the inside of the second mounting base (15). 5. A preparation device for nanometer test paper for monitoring diabetic retinopathy according to claim 4, characterized in that, the screw rod (105) is threadedly connected to the threaded through hole (102). 6. the preparation device of a kind of nano-test paper for monitoring diabetic retinopathy according to claim 5, is characterized in that, between described limiting plate (103) and described screw rod (105), be rotatably connected by bearing (104) . 7 . A preparation device for nanometer test paper for monitoring diabetic retinopathy according to claim 6 , characterized in that, a sliding connection between the limiting groove ( 23 ) and the limiting block ( 24 ).

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