CN113427559A - Nano fetuin test paper for monitoring diabetic retinopathy and preparation process thereof - Google Patents
Nano fetuin test paper for monitoring diabetic retinopathy and preparation process thereof Download PDFInfo
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- CN113427559A CN113427559A CN202110749355.0A CN202110749355A CN113427559A CN 113427559 A CN113427559 A CN 113427559A CN 202110749355 A CN202110749355 A CN 202110749355A CN 113427559 A CN113427559 A CN 113427559A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D11/00—Combinations of several similar cutting apparatus
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D1/00—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor
- B26D1/01—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work
- B26D1/04—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a linearly-movable cutting member
- B26D1/06—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a linearly-movable cutting member wherein the cutting member reciprocates
- B26D1/08—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a linearly-movable cutting member wherein the cutting member reciprocates of the guillotine type
- B26D1/085—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a linearly-movable cutting member wherein the cutting member reciprocates of the guillotine type for thin material, e.g. for sheets, strips or the like
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D5/00—Arrangements for operating and controlling machines or devices for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
- B26D5/08—Means for actuating the cutting member to effect the cut
- B26D5/12—Fluid-pressure means
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D5/00—Arrangements for operating and controlling machines or devices for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
- B26D5/20—Arrangements for operating and controlling machines or devices for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting with interrelated action between the cutting member and work feed
- B26D5/30—Arrangements for operating and controlling machines or devices for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting with interrelated action between the cutting member and work feed having the cutting member controlled by scanning a record carrier
- B26D5/34—Arrangements for operating and controlling machines or devices for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting with interrelated action between the cutting member and work feed having the cutting member controlled by scanning a record carrier scanning being effected by a photosensitive device
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
- B26D7/01—Means for holding or positioning work
- B26D7/015—Means for holding or positioning work for sheet material or piles of sheets
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
- B26D7/06—Arrangements for feeding or delivering work of other than sheet, web, or filamentary form
- B26D7/0625—Arrangements for feeding or delivering work of other than sheet, web, or filamentary form by endless conveyors, e.g. belts
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
- B26D7/26—Means for mounting or adjusting the cutting member; Means for adjusting the stroke of the cutting member
- B26D7/2628—Means for adjusting the position of the cutting member
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
Abstract
The invention discloses a process for monitoring diabetic retinopathy by using a nano fetuin test paper, which comprises a fetuin antibody, is used for detecting the fetuin content of serum or other body fluids and is used for monitoring the occurrence and development of diabetic retinopathy. When the preparation device provided by the invention is used, a worker places the prepared nano test paper on a conveyor belt, the conveyor belt transmits the nano test paper, the second air cylinder is started to drive the second cutting knife to vertically cut the nano test paper on the conveyor belt, the conveyor belt continues to transmit the nano test paper after the vertical cutting is finished, and the first air cylinder is started to drive the first cutting knife to transversely cut the nano test paper, so that the transverse cutting and the vertical cutting of the nano test paper can be simultaneously carried out, and the production efficiency of the nano test paper is improved.
Description
Technical Field
The invention relates to the technical field of nano test paper, in particular to a process for monitoring diabetic retinopathy by using nano fetuin test paper.
Background
Diabetic retinopathy is a common chronic complication of diabetes, belongs to retinal microvascular disease caused by diabetes, can cause blindness seriously, and seriously affects the life quality of patients. The early stage of diabetic retinopathy has no obvious symptoms, the incidence rate of the diabetic retinopathy is increased along with the prolonging of the course of the disease, and the symptoms of muscae volitantes, black shadows before eyes, blurred vision, visual field loss, vision loss and the like can appear, and the blindness-causing complications of vitreous hemorrhage and retinal detachment can also appear. Diabetic retinopathy is the most common cause of preventable blindness in adults. However, which diabetic patients may have diabetic retinopathy and diabetic retinopathy at which stage are unknown, and the diabetic retinopathy can only attract attention of the patients when bleeding clinical symptoms occur, certain serum biomarkers are changed before the diabetic retinopathy occurs, previous researches prove that fetuin is abnormally increased in serum and intraocular fluid of the diabetic retinopathy patients, and test paper is used for detecting the occurrence and the development of the diabetic retinopathy and is an early warning method.
In the existing preparation process of the nanometer test paper for diabetic retinopathy, cutting is needed after the nanometer test paper is prepared, and most of the existing nanometer test paper cutting devices are cut by a manual cutting machine, so that the cutting speed is low;
in the existing automatic nanometer test paper cutting machine, the stacked test paper cannot be cut, only single test paper can be cut, the cutting speed of the single test paper is low, and the production efficiency of the test paper is reduced;
in the existing cutting process of the nanometer test paper, the test paper is mostly transversely cut after being vertically cut, the vertical cutting and the transverse cutting are not coherent, the test paper can be cut only by integrally replacing the position of the test paper by a worker, the operation is troublesome, and the cutting efficiency of the test paper is reduced.
Therefore, the nano fetuin test paper for monitoring diabetic retinopathy and the preparation process thereof are provided.
Disclosure of Invention
The technical task of the invention is to provide a process for monitoring diabetic retinopathy by using a nano fetuin test paper, which aims at the defects, when the preparation device is used, a worker places the prepared test paper on a conveyor belt, transmits the test paper through the continuity of the conveyor belt, drives a second cutting knife to vertically cut the test paper through a second air cylinder, drives a first cutting knife to transversely cut the test paper through a first air cylinder, and limits the test paper through an electric push rod and a baffle, so that the worker can simultaneously cut multiple layers of test paper, and the cutting accuracy is ensured through a first infrared positioner and a second infrared positioner.
The technical scheme of the invention is realized as follows:
a process for monitoring diabetic retinopathy by using nano fetuin test paper,
including nanometer fetuin test paper, nanometer fetuin test paper includes two nano-electrode basic units, two the outside of nano-electrode basic unit all bonds and has the sign surface course, two the outside of nano-electrode basic unit bonds and has the sign surface course, two the inside of nano-electrode basic unit all bonds and has led the blood layer, two the outside of nano-electrode basic unit all bonds and has the enzyme layer, one the outside of nano-electrode basic unit bonds and has the viscose layer, another the outside of nano-electrode basic unit bonds and has antiseized layer.
Preferably, the marking surface layer is in a ring barrel shape, and the two nano electrode base layers are both adhered to the inside of the marking surface layer.
Preferably, the blood conduction layer is located between the anti-adhesion layer and one of the nano-electrode substrates.
The invention also provides a preparation process of the nano test paper for monitoring diabetic retinopathy, which comprises the following steps:
s1, placing the produced nano fetuin test paper on a conveyor belt by an operator, starting the conveyor belt at the same time, driving the produced nano fetuin test paper to be conveyed after the conveyor belt is started, and in the conveying process of the test paper, the operator determines the conveying position of the nano fetuin test paper by starting a plurality of first infrared positioners, so that the conveying position error of the nano fetuin test paper is avoided, and meanwhile, the starting of the first infrared positioners can assist the conveyor belt to convey the produced test paper to the specified position, so that the dislocation phenomenon caused by the conveying of the test paper is avoided;
s2, after the test paper is conveyed to the designated position by the conveyor belt, a worker starts a second air cylinder, the starting of the second air cylinder drives the mounting plate and a second cutting knife to adjust the vertical position, and the adjustment of the vertical position of the second cutting knife vertically cuts the nano fetuin test paper on the conveyor belt;
s3, when the vertical cutting of the nano fetuin test paper is finished, the worker continuously starts the conveyor belt, the conveyor belt continuously conveys the nano fetuin test paper, and meanwhile, the rodless cylinder is started to drive the first cylinder and the first cutting knife to adjust the front and back positions;
s4, after adjusting the first cylinder and the first cutter to the designated position, the staff starts the electric push rod, the starting of the electric push rod can drive the baffle to adjust the position, the nanometer fetuin test paper after the vertical cutting is limited through the baffle, the first cutter is started after the nanometer fetuin test paper is limited, and the first cutter is driven by the first cylinder to transversely cut the nanometer fetuin test paper.
Preferably, when the rodless cylinder drives the second mounting seat and the first cutting knife to move, the second infrared positioner located in the second mounting seat is simultaneously driven to adjust the position, the position of the first cutting knife for transverse cutting is located through the second infrared positioner, and therefore the phenomenon that errors are generated in transverse cutting is avoided.
As preferred, when first infrared locator used, be located inside spacing groove of shell and stopper and can adjust the position of first infrared locator, through the position adjustment to first infrared locator, adapt to the width cutting condition of different nanometer fetuin test paper.
The invention also provides a preparation device of the nanometer test paper for monitoring diabetic retinopathy, which comprises the following components: a cutting structure and a limiting structure;
wherein, the cutting structure is used for transversely cutting and vertically cutting the test paper and adjusting the position of the cutter, the cutting structure comprises a bottom plate, a shell, a rodless cylinder, a first mounting seat, a first cylinder, a second mounting seat, a first cutting knife, a third mounting seat, a second cylinder, a plurality of mounting plates, a conveyor belt, a threaded through hole, a limiting plate, a bearing, a screw rod and a second cutting knife, the shell is arranged on the bottom plate, the rodless cylinder is arranged in the shell, the first mounting seat is fixedly arranged at the slide block of the rodless cylinder, the first cylinder is arranged outside the first mounting seat, the second mounting seat is fixedly arranged at the end part of the piston rod of the first cylinder, the first cutting knife is fixedly arranged on the second mounting seat, the third mounting seat is fixedly arranged in the shell, the second cylinder is arranged outside the third mounting seat, the mounting plate is fixedly mounted at the end part of the piston rod of the second cylinder, the thread through holes are formed in the mounting plate, the conveyor belt is mounted on the bottom plate, the screw is movably connected in the thread through holes and is movably connected to the limiting plate, and the second cutting knife is mounted on the limiting plate;
wherein, limit structure is used for cutting the in-process nanometer fetuin test paper carries on spacingly to avoid the position that the cutter cut to produce the mistake, limit structure includes electric putter, baffle, a plurality of first infrared locator, spacing groove, stopper and a plurality of second infrared locator, the spacing groove is seted up in the inside of shell, stopper swing joint in the inside of spacing groove, first infrared locator fixed mounting in the outside of spacing groove, second infrared locator install in the inside of second mount pad.
Preferably, the screw rod is in threaded connection with the threaded through hole.
Preferably, the limiting plate is rotatably connected with the screw rod through a bearing.
Preferably, the limiting groove is in sliding connection with the limiting block.
Compared with the prior art, the invention has the advantages and positive effects that:
1. when the preparation device provided by the invention is used, a worker places the prepared nano test paper on a conveyor belt, the conveyor belt is used for transmission, the second air cylinder is started to drive the second cutting knife to vertically cut the nano test paper on the conveyor belt, the conveyor belt is used for continuously transmitting the nano test paper after the vertical cutting is finished, and the first air cylinder is started to drive the first cutting knife to transversely cut the nano test paper, so that the transverse cutting and the vertical cutting of the nano test paper can be simultaneously carried out, and the production efficiency of the nano test paper is improved;
2. when the preparation device provided by the invention is used, in the process of cutting the nanometer test paper, a worker can avoid the transmission error of the nanometer test paper by starting the first infrared positioner, and the first infrared positioner is arranged, and meanwhile, the rodless cylinder can be started to drive the second mounting seat and the second infrared positioner to carry out position adjustment, and the cutting position of the first cutting knife can be positioned by the position adjustment of the second infrared positioner, so that the phenomenon of cutting error is avoided;
3. according to the invention, the two nanometer electrode base layers are bonded through the identification surface layer, and the blood guide layers are respectively arranged in the two nanometer electrode base layers, so that when the test result of the blood glucose test paper is inaccurate, a user can separate the adhesive layer from the anti-sticking layer, a new blood glucose test paper can be formed between the two nanometer electrode base layers, secondary test can be carried out, the use of the user is convenient, and the waste of the test paper is reduced.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.
FIG. 1 is a schematic flow chart of a process for preparing a nano test paper for monitoring diabetic retinopathy according to an embodiment of the present invention;
FIG. 2 is a schematic structural diagram of a nano-test paper preparation device for monitoring diabetic retinopathy according to the present invention;
FIG. 3 is a schematic cross-sectional view of an apparatus for preparing a nano-strip for monitoring diabetic retinopathy according to the present invention;
FIG. 4 is a schematic structural diagram of another view angle of the apparatus for preparing a nano-test paper for monitoring diabetic retinopathy according to the present invention;
FIG. 5 is an enlarged view of the area A in FIG. 2;
FIG. 6 is a schematic structural diagram of a screw and a limiting plate in the nano-test paper preparation apparatus for monitoring diabetic retinopathy according to the present invention;
FIG. 7 is a schematic structural diagram of a mounting plate and a threaded through hole in the nano-test paper preparation apparatus for monitoring diabetic retinopathy according to the present invention;
FIG. 8 is a schematic structural diagram of a nano-test strip for monitoring diabetic retinopathy according to an embodiment of the present invention;
FIG. 9 is a schematic diagram of a side view of a nano-test strip for monitoring diabetic retinopathy according to an embodiment of the present invention;
FIG. 10 is a second schematic sectional view of the apparatus for preparing nano-strip for monitoring diabetic retinopathy according to the present invention;
FIG. 11 is a schematic diagram showing a side view of a device for preparing a nano-test paper for monitoring diabetic retinopathy according to the present invention;
FIG. 12 is a third schematic sectional view of an apparatus for preparing a nano-strip for monitoring diabetic retinopathy according to the present invention.
In the figure:
1. cutting the structure; 10. a base plate; 11. a housing; 12. a rodless cylinder; 13. a first mounting seat; 14. a first cylinder; 15. a second mounting seat; 16. a first cutting knife; 17. a third mounting seat; 18. a second cylinder; 19. mounting a plate; 101. a conveyor belt; 102. a threaded through hole; 103. a limiting plate; 104. a bearing; 105. a screw; 106. a second cutting knife;
2. a limiting structure; 20. an electric push rod; 21. a baffle plate; 22. a first infrared locator; 23. a limiting groove; 24. a limiting block; 25. a second infrared locator;
3. nano fetuin test paper; 31. a nano-electrode base layer; 32. marking the surface layer; 33. a blood conduction layer; 34. an enzyme layer; 35. an adhesive layer; 36. and (4) an anti-sticking layer.
Detailed Description
In order that the above objects, features and advantages of the present invention can be more clearly understood, the present invention will be further described with reference to the accompanying drawings and examples. It should be noted that the embodiments and features of the embodiments of the present application may be combined with each other without conflict.
The invention is further described with reference to the following figures and specific examples.
Example 1
As shown in fig. 1, the invention also provides a preparation process of the nano test paper for monitoring diabetic retinopathy, which comprises the following steps:
s1, placing the produced nano fetuin test paper 3 on a conveyor belt 101 by an operator, starting the conveyor belt 101 at the same time, driving the produced nano fetuin test paper 3 to be conveyed after the conveyor belt 101 is started, and in the conveying process of the test paper, the operator determines the conveying position of the nano fetuin test paper 3 by starting a plurality of first infrared locators 22 through the first infrared locators 22, so that the conveying position error of the nano fetuin test paper 3 is avoided, and meanwhile, the starting of the first infrared locators 22 assists the conveyor belt 101 in conveying the produced test paper to a specified position, so that the dislocation phenomenon caused by the conveying of the test paper is avoided;
s2, after the test paper is conveyed to a designated position by the conveyor belt 101, the worker starts the second cylinder 18, the start of the second cylinder 18 drives the mounting plate 19 and the second cutting knife 106 to perform vertical position adjustment, and the vertical position adjustment of the second cutting knife 106 performs vertical cutting on the nano fetuin test paper 3 on the conveyor belt 101;
s3, when the nano fetuin test paper 3 is vertically cut, the worker continuously starts the conveyor belt 101, the conveyor belt 101 continuously conveys the nano fetuin test paper 3, and simultaneously the rodless cylinder 12 is started to drive the first cylinder 14 and the first cutting knife 16 to adjust the front and back positions;
s4, after adjusting assigned position with first cylinder 14 and first sword 16 that cuts, the staff starts electric putter 20, electric putter 20' S start can drive baffle 21 and carry out the position adjustment, it is spacing to cut the nanometer fetuin test paper 3 after accomplishing perpendicularly through baffle 21, carry out spacing completion to nanometer fetuin test paper 3 and start first sword 16 that cuts, drive first sword 16 that cuts through first cylinder 14 and carry out the crosscut to nanometer fetuin test paper 3.
Specifically, when the rodless cylinder 12 drives the second mounting base 15 and the first cutting knife 16 to move, the second infrared positioner 25 located inside the second mounting base 15 is simultaneously driven to perform position adjustment, and the position of the first cutting knife 16 for transverse cutting is positioned through the second infrared positioner 25, so that the phenomenon of error in transverse cutting is avoided;
by adopting the above technical scheme, the position of the second infrared positioner 25 can be adjusted under the driving of the rodless cylinder 12, and the position of the test paper transmission can be monitored in real time by adjusting the position of the second infrared positioner 25.
Specifically, when first infrared locator 22 used, be located inside spacing groove 23 of shell 11 and stopper 24 and can adjust first infrared locator 22's position, through the position adjustment to first infrared locator 22, adapt to the width cutting condition of different nanometer fetuin test paper 3.
Example 2
As shown in fig. 1 to 6, a device for preparing a nano test paper for monitoring diabetic retinopathy according to an embodiment of the present invention includes: the cutting structure 1 and the limiting structure 2;
wherein, the cutting structure 1 is used for transversely and vertically cutting the test paper and adjusting the position of a cutting knife, the cutting structure 1 comprises a bottom plate 10, a shell 11, a rodless cylinder 12, a first mounting seat 13, a first cylinder 14, a second mounting seat 15, a first cutting knife 16, a third mounting seat 17, a second cylinder 18, a plurality of mounting plates 19, a conveyor belt 101, a threaded through hole 102, a limiting plate 103, a bearing 104, a screw 105 and a second cutting knife 106, the shell 11 is mounted on the bottom plate 10, the rodless cylinder 12 is mounted in the shell 11, the first mounting seat 13 is fixedly mounted at the sliding block of the rodless cylinder 12, the first cylinder 14 is mounted outside the first mounting seat 13, the second mounting seat 15 is fixedly mounted at the end part of the piston rod of the first cylinder 14, the first cutting knife 16 is fixedly mounted on the second mounting seat 15, the third mounting seat 17 is fixedly mounted inside the shell 11, the second cylinder 18 is mounted outside the third mounting seat 17, the mounting plate 19 is fixedly mounted at the end of the piston rod of the second cylinder 18, the plurality of threaded through holes 102 are all formed in the mounting plate 19, the conveyor belt 101 is mounted on the bottom plate 10, the screws 105 are movably connected to the inner screw 105 of the threaded through holes 102 and movably connected to the limiting plate 103, and the second cutting knife 106 is mounted on the limiting plate 103;
the limiting structure 2 is used for limiting the nano fetuin test paper 3 in the cutting process and avoiding errors in the cutting position of the cutter, the limiting structure 2 comprises an electric push rod 20, a baffle 21, a plurality of first infrared locators 22, a limiting groove 23, a limiting block 24 and a plurality of second infrared locators 25, the limiting groove 23 is formed in the shell 11, the limiting block 24 is movably connected into the limiting groove 23, the first infrared locators 22 are fixedly installed outside the limiting groove 23, and the second infrared locators 25 are installed in the second installation seat 15;
by adopting the technical scheme, when the scheme is used, a worker places the manufactured test paper on the conveyor belt 101, and starts the conveyor belt 101, the conveyor belt 101 is started to drive the nano fetuin test paper 3 to be conveyed, meanwhile, the worker can start the first infrared positioner 22, the nano test paper which is conveyed is positioned by starting the first infrared positioner 22, the test paper conveying position error is avoided, after the nano test paper is conveyed to a specified position, the worker can start the second cylinder 18, the second cylinder 18 is started to drive the mounting plate 19 and the second cutting knife 106 to be adjusted up and down, so that the test paper is cut, meanwhile, the worker can install the limiting plate 103 and the second cutting knife 106 at different positions of the threaded through hole 102 through the screw 105, so that the mounting position of the second cutting knife 106 is adjusted, adapt to more circumstances of cutting, after the test paper erects to cut and accomplish, the staff can continue to start conveyer belt 101, test paper forward propelling movement after will erectly cutting the completion, and drive baffle 21 through starting electric putter 20 and carry on spacingly to the test paper, it drives first mount pad 13 and carries out front and back position adjustment to start rodless cylinder 12, the start-up of first mount pad 13 can drive first cylinder 14 and first sword 16 that cuts and carry out position adjustment, start first cylinder 14 and drive first sword 16 that cuts and carry out the crosscut to the test paper, thereby carry out the continuity to the nanometer test paper and cut, make the crosscut can accomplish simultaneously with erectting, and the mode through first cylinder 14 and second cylinder 18, can make the staff once only cut more nanometer test paper.
Specifically, the screw 105 is in threaded connection with the threaded through hole 102.
By adopting the technical scheme, the threaded connection between the screw 105 and the threaded through hole 102 is convenient for a worker to install the second cutting knife 106 on the mounting plate 19 through the screw 105.
Specifically, the limit plate 103 is rotatably connected with the screw 105 through a bearing 104.
By adopting the technical scheme, the limiting plate 103 is rotationally connected with the screw 105, so that a worker can conveniently connect the screw 105 into the threaded through hole 102 through the bearing 104.
Specifically, the limiting groove 23 is slidably connected with the limiting block 24.
Through adopting above-mentioned technical scheme, stopper 24 sliding connection is in the inside of spacing groove 23, provides the removal orbit through spacing groove 23 to stopper 24, carries out spacing fixed to stopper 24 through spacing groove 23 simultaneously.
Example 3
As shown in fig. 8 to 9, this embodiment is different from embodiment 1 in that the present invention further provides a nano test paper for monitoring diabetic retinopathy, which includes a nano fetuin test paper 3, where the nano fetuin test paper 3 includes two nano electrode substrates 31, identification surface layers 32 are bonded to the outer portions of the two nano electrode substrates 31, the identification surface layers 32 are bonded to the outer portions of the two nano electrode substrates 31, blood guiding layers 33 are bonded to the inner portions of the two nano electrode substrates 31, enzyme layers 34 are bonded to the outer portions of the two nano electrode substrates 31, an adhesive layer 35 is bonded to the outer portion of one nano electrode substrate 31, and an anti-sticking layer 36 is bonded to the outer portion of the other nano electrode substrate 31;
adopt above-mentioned technical scheme, sign surface course 32 is the sleeve form, two nano electrode basic unit 31 paste in the inside of sign surface course 32, the first half of two nano electrode basic unit 31 bonds each other, the part of going to work is in the same place through viscose layer 35 and antiseized layer 36 bonding, viscose layer 35 is the waterborne adsorbed layer, can adsorb mutually with antiseized layer 36, nevertheless do not possess viscidity, collect blood through leading blood layer 33 during the use, and strengthen monitoring effect through two nano electrode basic unit 31 and enzyme layer 34, when the measuring effect is unsatisfactory simultaneously, can part two nano electrode basic unit 31's the latter half, carry out the independent test, save the waste of test paper.
For the convenience of understanding the technical solutions of the present invention, the following detailed description will be made on the working principle or the operation mode of the present invention in the practical process.
In practical application, an operator places the manufactured test paper on the conveyor belt 101, and by starting the conveyor belt 101, the conveyor belt 101 is started to drive the nano fetuin test paper 3 to be conveyed, meanwhile, the operator can start the first infrared positioner 22, the nano test paper being conveyed is positioned by starting the first infrared positioner 22, so that the test paper conveying position error is avoided, after the nano test paper is conveyed to a specified position, the operator can start the second cylinder 18, the second cylinder 18 is started to drive the mounting plate 19 and the second cutting knife 106 to adjust the up-and-down position, so as to cut the test paper, after the test paper is vertically cut, the operator can continue to start the conveyor belt 101 to push the vertically cut test paper forwards, and the electric push rod 20 is started to drive the baffle plate 21 to limit the test paper, and after the test paper is pushed to the specified position, the rodless cylinder 12 is started to drive the first mounting seat 13 to adjust the front and back positions, the first mounting seat 13 is started to drive the first cylinder 14 and the first cutting knife 16 to adjust the positions, the first cylinder 14 is started to drive the first cutting knife 16 to transversely cut the test paper, so that the nano test paper is continuously cut, the transverse cutting and the vertical cutting can be simultaneously completed, in addition, by means of the first cylinder 14 and the second cylinder 18, a worker can cut more nano test paper at one time, meanwhile, in the use of the test paper, the user can collect the blood of a human body through the blood guiding layer 33, the monitoring effect is enhanced through the two nano electrode base layers 31 and the enzyme layer 34, meanwhile, when the measuring effect is not ideal, the blood guiding layers 33 of the two nano electrode base layers 31 can be separated, so that the worker can perform secondary blood sampling detection and perform independent testing, the waste of the test paper is saved.
The present invention can be easily implemented by those skilled in the art from the above detailed description. It should be understood, however, that the intention is not to limit the invention to the particular embodiments described. On the basis of the disclosed embodiments, a person skilled in the art can combine different technical features at will, thereby implementing different technical solutions.
Claims (10)
1. The utility model provides a nanometer test paper of monitoring diabetes retinopathy, its characterized in that, includes nanometer fetuin antibody test paper (3), nanometer fetuin test paper (3) include two nanometer electrode basic units (31), two the outside of nanometer electrode basic unit (31) all bonds and has sign surface course (32), two the outside of nanometer electrode basic unit (31) bonds and has sign surface course (32), two the inside of nanometer electrode basic unit (31) all bonds and has leads blood layer (33), two the outside of nanometer electrode basic unit (31) all bonds and has enzyme layer (34), one the outside of nanometer electrode basic unit (31) bonds and has viscose layer (35), another the outside of nanometer electrode basic unit (31) bonds and has antiseized layer (36).
2. The nano test paper for monitoring diabetic retinopathy according to claim 1, wherein the marking surface layer (32) is in a ring barrel shape, and both the nano electrode base layers (31) are adhered to the inside of the marking surface layer (32).
3. The nanopipette for monitoring diabetic retinopathy according to claim 1, wherein the blood conduction layer (33) is located between the anti-adhesion layer (36) and one of the nano-electrode substrates (31).
4. A process for preparing the nano test paper for monitoring diabetic retinopathy according to claim 1, which is used for producing the nano test paper for monitoring diabetic retinopathy according to claim 1, and comprises the following steps:
s1, the worker places the produced nano fetuin test paper (3) on a conveyor belt (101), the conveyor belt (101) is started simultaneously, the conveyor belt (101) is started to drive the produced nano fetuin test paper (3) to be transmitted, in the process of transmitting the test paper, the worker determines the transmission position of the nano fetuin test paper (3) by starting a plurality of first infrared locators (22), the first infrared locators (22) can determine the transmission position of the nano fetuin test paper (3), errors in the transmission position of the nano fetuin test paper (3) are avoided, meanwhile, the first infrared locators (22) are started to assist the conveyor belt (101) to transmit the produced test paper to a designated position, and the test paper transmission is prevented from generating a dislocation phenomenon;
s2, after the test paper is conveyed to a designated position by the conveyor belt (101), a worker starts the second cylinder (18), the second cylinder (18) is started to drive the mounting plate (19) and the second cutting knife (106) to adjust the vertical position, and the second cutting knife (106) adjusts the vertical position to vertically cut the nano fetuin test paper (3) on the conveyor belt (101);
s3, when the nano fetuin test paper (3) is vertically cut, the worker continuously starts the conveyor belt (101), the conveyor belt (101) continuously transmits the nano fetuin test paper (3), and meanwhile, the rodless cylinder (12) is started to drive the first cylinder (14) and the first cutting knife (16) to adjust the front position and the rear position;
s4, after adjusting appointed position with first cylinder (14) and first sword (16) of cutting, the staff starts electric putter (20), the start-up of electric putter (20) can drive baffle (21) and carry out the position control, it is spacing to cut nanometer fetuin test paper (3) after accomplishing perpendicularly through baffle (21), carry out spacing completion to nanometer fetuin test paper (3) and start first sword (16) of cutting, drive first sword (16) of cutting through first cylinder (14) and carry out the crosscut to nanometer fetuin test paper (3).
5. The preparation process of the nano test paper for monitoring diabetic retinopathy according to claim 4, wherein the rodless cylinder (12) drives the second mounting seat (15) and the first cutting knife (16) to move, and simultaneously drives the second infrared positioner (25) located inside the second mounting seat (15) to perform position adjustment, and the second infrared positioner (25) is used for positioning the position where the first cutting knife (16) performs transverse cutting, so as to avoid the phenomenon of error in transverse cutting.
6. The preparation method of the nano test paper for monitoring diabetic retinopathy according to claim 5, wherein when the first infrared positioner (22) is used, the position of the first infrared positioner (22) can be adjusted by the limiting groove (23) and the limiting block (24) located inside the housing (11), and the width cutting condition of different nano fetuin test paper (3) can be adapted by adjusting the position of the first infrared positioner (22).
7. The apparatus for preparing a nano test paper for monitoring diabetic retinopathy according to claim 6, comprising: the cutting structure (1) and the limiting structure (2);
wherein, cutting structure (1) is used for crosscut and vertical cutting to the test paper to the position of adjustment cutter, cutting structure (1) includes bottom plate (10), shell (11), rodless cylinder (12), first mount pad (13), first cylinder (14), second mount pad (15), first sword (16) of cutting, third mount pad (17), second cylinder (18), a plurality of mounting panel (19), conveyer belt (101), screw thread through-hole (102), limiting plate (103), bearing (104), screw rod (105) and second sword (106) of cutting, shell (11) are installed on bottom plate (10), rodless cylinder (12) are installed in the inside of shell (11), first mount pad (13) fixed mounting in rodless cylinder's (12) slider department, first cylinder (14) are installed in the outside of first mount pad (13), the second mounting seat (15) is fixedly mounted at the end part of a piston rod of the first air cylinder (14), the first cutting knife (16) is fixedly arranged on the second mounting seat (15), the third mounting seat (17) is fixedly arranged inside the shell (11), the second air cylinder (18) is arranged outside the third mounting seat (17), the mounting plate (19) is fixedly mounted at the end part of the piston rod of the second cylinder (18), the plurality of threaded through holes (102) are all arranged in the mounting plate (19), the conveyor belt (101) is arranged on the bottom plate (10), the screw rod (105) is movably connected inside the threaded through hole (102), the screw (105) is movably connected to the limiting plate (103), and the second cutting knife (106) is installed on the limiting plate (103);
wherein, limit structure (2) are used for cutting the in-process nanometer fetuin test paper (3) carry on spacingly to avoid the position that the cutter cut to produce the mistake, limit structure (2) include electric putter (20), baffle (21), a plurality of first infrared locator (22), spacing groove (23), stopper (24) and a plurality of second infrared locator (25), spacing groove (23) are seted up in the inside of shell (11), stopper (24) swing joint in the inside of spacing groove (23), first infrared locator (22) fixed mounting in the outside of spacing groove (23), second infrared locator (25) install in the inside of second mount pad (15).
8. The device for preparing the nano test paper for monitoring diabetic retinopathy according to claim 7, wherein the screw rod (105) is in threaded connection with the threaded through hole (102).
9. The device for preparing the nano test paper for monitoring diabetic retinopathy according to claim 8, wherein the limiting plate (103) and the screw rod (105) are rotatably connected through a bearing (104).
10. The device for preparing the nano test paper for monitoring diabetic retinopathy according to claim 9, wherein the limiting groove (23) is slidably connected with the limiting block (24).
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| CN202110749355.0A CN113427559B (en) | 2021-07-02 | 2021-07-02 | Nano fetuin test paper for monitoring diabetic retinopathy and preparation process thereof |
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| CN113427559B (en) | 2023-03-10 |
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