CN113368197A - Mosquito-repellent spray and preparation method thereof - Google Patents

Abstract

The invention discloses a mosquito-free spray and a preparation method thereof, wherein the mosquito-free spray comprises the following raw materials in parts by weight: 5-11% of ethanol by mass; 6-10% of polyethylene glycol; 3-5% of lemongrass extract; 4-7% of wormwood extract; 2-4% of honeysuckle flower extract; 3-5% of wild chrysanthemum extract by mass; purified water accounts for 60-80% by mass; 1-2% of modifier and 1-3% of defoaming agent. The invention realizes disinfection and sterilization on the surface of the skin, enhances the anti-allergic capacity of the skin, reduces the occurrence of various allergic diseases, has a certain treatment effect on common skin diseases such as allergic dermatitis, eczema, mange and the like, and has the function of absorbing ultraviolet rays.

Description

Mosquito-repellent spray and preparation method thereof

Technical Field

The invention relates to the technical field of mosquito-free spraying agents, in particular to a mosquito-free spraying agent and a preparation method thereof.

Background

Mosquitoes are one of four pests and are carriers of viruses. Along with the development of society, the living standard of human beings is continuously improved, the consciousness of people on health and self-protection is continuously increased, and various mosquito repellent products are produced in succession.

At present, the existing mosquito-free spray has some defects, such as; the existing mosquito-repellent spray can not disinfect and sterilize the surface of skin, bacteria easily permeate into the skin to cause the propagation of the bacteria, the protection effect on the skin of a human body is reduced, the anti-allergic capability of the skin and the antibacterial, anti-inflammatory and antiviral effects of the skin are poor, the occurrence of various allergic diseases is increased, a certain treatment effect on common skin diseases such as allergic dermatitis, eczema, mange and the like can not be realized, the function of absorbing ultraviolet rays is not realized, and the good maintenance effect on the skin can not be realized.

Disclosure of Invention

The invention aims to provide a preparation method of a mosquito-free spray, which solves the problems in the background art.

In order to achieve the purpose, the invention provides the following technical scheme: the preparation method of the mosquito-free spray comprises the following raw materials in parts by weight: 5-11% of ethanol by mass; 6-10% of polyethylene glycol; 3-5% of lemongrass extract; 4-7% of wormwood extract; 2-4% of honeysuckle flower extract; 3-5% of wild chrysanthemum extract by mass; purified water accounts for 60-80% by mass; 1-2% of modifier and 1-3% of defoaming agent.

As a preferred embodiment of the invention, the mosquito-free spray comprises the following raw materials in parts by weight: 5% by mass of ethanol; 6% of polyethylene glycol; the mass part of the lemongrass extract is 3 percent; 4% of wormwood extract; 2% of honeysuckle flower extract; 3% of wild chrysanthemum extract by mass; 75% by mass of purified water; 1% by mass of a modifier and 1% by mass of a defoaming agent.

As a preferred embodiment of the invention, the mosquito-free spray comprises the following raw materials in parts by weight: 8% of ethanol by mass; 7% of polyethylene glycol; the mass part of the lemongrass extract is 4 percent; 6% of wormwood extract; the honeysuckle flower extract accounts for 3 mass percent; the wild chrysanthemum extract accounts for 4 mass percent; 64% by mass of purified water; 2% by mass of a modifier and 2% by mass of a defoaming agent.

As a preferred embodiment of the present invention, the preparation method of the mosquito-free spray comprises the following steps:

a. weighing the raw materials in parts by weight;

b. b, after the step a is finished, putting the weighed purified water into a mixer, then adding ethanol, polyethylene glycol, a lemongrass extract, a wormwood extract, a honeysuckle extract and a wild chrysanthemum extract into the mixer for mixing, wherein the rotating speed during mixing is 500-650 r/min, the mixing time is 20-30 min, and the mixing temperature is 40-50 ℃ to prepare a mixture A;

c. after the step B is finished, adding the modifier into the mixture A for mixing, wherein the rotating speed during mixing is 500-650 r/min, the mixing time is 10-15 min, and the mixing temperature is 30-60 ℃ to obtain a mixture B;

d. after the step C is finished, adding a defoaming agent into the mixture B for mixing to obtain a mixture C;

e. after the step d is finished, filtering, standing and sterilizing the mixed mixture C to prepare the mosquito-free spraying agent;

f. and e, after the step e is finished, finally canning and boxing the prepared mosquito-free spraying agent.

In a preferred embodiment of the present invention, the modifier is an aqueous solution of one or more of ethylenediamine tetraacetic acid, polyvinylpyrrolidone, polyvinyl alcohol, and a silane coupling agent.

As a preferred embodiment of the present invention, the antifoaming agent is C_8-10Fatty alcohols, C_10-20Saturated fatty acids or silicone oil.

In a preferred embodiment of the present invention, the mixture C in step e is filtered, left to stand and sterilized, the mixture C is filtered by using an ultrafiltration membrane, the number of times of filtering is 2-3, and the time of left to stand is 50-70 min.

In a preferred embodiment of the present invention, the mosquito-repellent spray in step e is canned and packaged in 60 ml/bottle, and each box contains 12 bottles.

As a preferred embodiment of the present invention, the wormwood extract is prepared by the following steps:

s1, adding petroleum ether with a fixed boiling range into crushed folium artemisiae argyi according to a material-liquid ratio of 1: 7-1: 10(m/v), fully soaking, extracting under the assistance of ultrasonic waves, separating a solid phase from a liquid phase after extraction is finished, wherein the solid phase is the crushed folium artemisiae argyi;

s2, taking a solid phase, repeating the steps for a plurality of times of soaking, extracting for 2-3 times, separating to obtain degreased folium artemisiae argyi, extracting the degreased folium artemisiae argyi for three times by using 85-95% ethanol according to a material-liquid ratio under the assistance of ultrasound, combining extracting solutions obtained by three times of extraction, filtering the extracting solutions, and concentrating the extracting solutions to a certain proportion by using a rotary evaporator to obtain a concentrated solution;

s3, fully mixing the prepared concentrated solution with distilled water according to the volume ratio of 1: 4-6 to obtain a mixed solution, putting the mixed solution into a high-speed centrifuge, and collecting supernatant after centrifugation is finished;

and S4, finally, filtering the collected supernatant, freezing for a period of time, and removing water to obtain the non-volatile folium artemisiae argyi extract.

Compared with the prior art, the invention has the following beneficial effects:

1. according to the invention, the lemongrass extract is added into the mosquitocis-free spray, so that the disinfection and sterilization of the skin surface are effectively realized, the propagation of bacteria caused by the penetration of the bacteria into the skin is avoided, and the protection effect on the skin of a human body is improved.

2. According to the invention, the wormwood extract is added into the masquito-free spray, so that the antiallergic capability of the skin is effectively enhanced, the occurrence of various allergic diseases is reduced, and a certain treatment effect on common skin diseases such as allergic dermatitis, eczema, mange and the like is achieved, so that the effects of quickly relieving pain and itching are achieved.

3. According to the invention, the honeysuckle flower extract and the wild chrysanthemum flower extract are added into the mosquitocis-free spray, so that the antibacterial, anti-inflammatory and antiviral effects of skin are effectively enhanced, and the composition has the function of absorbing ultraviolet rays and can also have a good skin care effect.

Detailed Description

Technical solutions in the embodiments of the present invention are clearly and completely described, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments.

The invention provides a technical scheme that: the preparation method of the mosquito-free spray comprises the following raw materials in parts by weight: 5-11% of ethanol by mass; 6-10% of polyethylene glycol; 3-5% of lemongrass extract; 4-7% of wormwood extract; 2-4% of honeysuckle flower extract; 3-5% of wild chrysanthemum extract by mass; purified water accounts for 60-80% by mass; 1-2% of modifier and 1-3% of defoaming agent.

Further, the mosquito-repellent spray comprises the following raw materials in parts by weight: 5% by mass of ethanol; 6% of polyethylene glycol; the mass part of the lemongrass extract is 3 percent; 4% of wormwood extract; 2% of honeysuckle flower extract; 3% of wild chrysanthemum extract by mass; 75% by mass of purified water; 1% by mass of a modifier and 1% by mass of a defoaming agent.

Further, the mosquito-repellent spray comprises the following raw materials in parts by weight: 8% of ethanol by mass; 7% of polyethylene glycol; the mass part of the lemongrass extract is 4 percent; 6% of wormwood extract; the honeysuckle flower extract accounts for 3 mass percent; the wild chrysanthemum extract accounts for 4 mass percent; 64% by mass of purified water; 2% by mass of a modifier and 2% by mass of a defoaming agent.

Further, the preparation method of the mosquito-repellent spray comprises the following steps:

a. weighing the raw materials in parts by weight;

b. b, after the step a is finished, putting the weighed purified water into a mixer, then adding ethanol, polyethylene glycol, a lemongrass extract, a wormwood extract, a honeysuckle extract and a wild chrysanthemum extract into the mixer for mixing, wherein the rotating speed during mixing is 500-650 r/min, the mixing time is 20-30 min, and the mixing temperature is 40-50 ℃ to prepare a mixture A;

c. after the step B is finished, adding the modifier into the mixture A for mixing, wherein the rotating speed during mixing is 500-650 r/min, the mixing time is 10-15 min, and the mixing temperature is 30-60 ℃ to obtain a mixture B;

d. after the step C is finished, adding a defoaming agent into the mixture B for mixing to obtain a mixture C;

e. after the step d is finished, filtering, standing and sterilizing the mixed mixture C to prepare the mosquito-free spraying agent;

f. and e, after the step e is finished, finally canning and boxing the prepared mosquito-free spraying agent.

Further, the modifier is one or more aqueous solutions of ethylene diamine tetraacetic acid, polyvinylpyrrolidone, polyvinyl alcohol and silane coupling agent.

Further, the defoaming agent is C_8-10Fatty alcohols, C_10-20Saturated fatty acids or silicone oil.

Further, the mixture C in the step e is filtered, kept stand and sterilized, the mixture C is filtered by an ultrafiltration membrane, the filtering frequency is 2-3 times, and the standing time is 50-70 min.

Further, in the step e, the mosquito-repellent spray is canned and boxed, wherein each box contains 12 bottles of 60 ml/bottle.

Further, the preparation steps of the wormwood extract are as follows:

s1, adding petroleum ether with a fixed boiling range into crushed folium artemisiae argyi according to a material-liquid ratio of 1: 7-1: 10(m/v), fully soaking, extracting under the assistance of ultrasonic waves, separating a solid phase from a liquid phase after extraction is finished, wherein the solid phase is the crushed folium artemisiae argyi;

s2, taking a solid phase, repeating the steps for a plurality of times of soaking, extracting for 2-3 times, separating to obtain degreased folium artemisiae argyi, extracting the degreased folium artemisiae argyi for three times by using 85-95% ethanol according to a material-liquid ratio under the assistance of ultrasound, combining extracting solutions obtained by three times of extraction, filtering the extracting solutions, and concentrating the extracting solutions to a certain proportion by using a rotary evaporator to obtain a concentrated solution;

s3, fully mixing the prepared concentrated solution with distilled water according to the volume ratio of 1: 4-6 to obtain a mixed solution, putting the mixed solution into a high-speed centrifuge, and collecting supernatant after centrifugation is finished;

and S4, finally, filtering the collected supernatant, freezing for a period of time, and removing water to obtain the non-volatile folium artemisiae argyi extract.

Example one

The mosquito-repellent spray comprises the following raw materials in parts by weight: 5% by mass of ethanol; 6% of polyethylene glycol; the mass part of the lemongrass extract is 3 percent; 4% of wormwood extract; 2% of honeysuckle flower extract; 3% of wild chrysanthemum extract by mass; 75% by mass of purified water; 1% by mass of a modifier and 1% by mass of a defoaming agent.

The preparation method of the mosquito-repellent spray comprises the following steps:

a. weighing the raw materials in parts by weight;

b. b, after the step a is finished, putting the weighed purified water into a mixer, adding ethanol, polyethylene glycol, a lemongrass extract, a wormwood extract, a honeysuckle extract and a wild chrysanthemum extract into the mixer, and mixing at the rotation speed of 650r/min for 20min at the mixing temperature of 40 ℃ to obtain a mixture A;

c. after the step B is finished, adding the modifier into the mixture A for mixing, wherein the rotating speed during mixing is 500r/min, the mixing time is 15min, and the mixing temperature is 30 ℃ to obtain a mixture B;

d. after the step C is finished, adding a defoaming agent into the mixture B for mixing to obtain a mixture C;

e. after the step d is finished, filtering, standing and sterilizing the mixed mixture C to prepare the mosquito-free spraying agent;

f. and e, after the step e is finished, finally canning and boxing the prepared mosquito-free spraying agent.

Example two

The mosquito-repellent spray comprises the following raw materials in parts by weight: 8% of ethanol by mass; 7% of polyethylene glycol; the mass part of the lemongrass extract is 4 percent; 6% of wormwood extract; the honeysuckle flower extract accounts for 3 mass percent; the wild chrysanthemum extract accounts for 4 mass percent; 64% by mass of purified water; 2% by mass of a modifier and 2% by mass of a defoaming agent.

The preparation method of the mosquito-repellent spray comprises the following steps:

a. weighing the raw materials in parts by weight;

b. b, after the step a is finished, putting the weighed purified water into a mixer, adding ethanol, polyethylene glycol, a lemongrass extract, a wormwood extract, a honeysuckle extract and a wild chrysanthemum extract into the mixer, and mixing at the rotation speed of 650r/min for 20min at the mixing temperature of 40 ℃ to obtain a mixture A;

c. after the step B is finished, adding the modifier into the mixture A for mixing, wherein the rotating speed during mixing is 500r/min, the mixing time is 15min, and the mixing temperature is 30 ℃ to obtain a mixture B;

d. after the step C is finished, adding a defoaming agent into the mixture B for mixing to obtain a mixture C;

e. after the step d is finished, filtering, standing and sterilizing the mixed mixture C to prepare the mosquito-free spraying agent;

f. and e, after the step e is finished, finally canning and boxing the prepared mosquito-free spraying agent.

Data parameters of the traditional mosquito-free spray are shown in the table 1 as follows:

example data parameters for a no mosquito spray are shown in table 2 below:

example two mosquito repellent free spray data parameters table 3 are as follows:

in conclusion, the data in tables 1, 2 and 3 are compared to obtain, and the lemongrass extract is added into the mosquito-free spray, so that the skin surface can be effectively disinfected and sterilized, the propagation of bacteria caused by the fact that the bacteria permeate into the skin is avoided, and the protection effect on the skin of a human body is improved. According to the invention, the wormwood extract is added into the masquito-free spray, so that the antiallergic capability of the skin is effectively enhanced, the occurrence of various allergic diseases is reduced, and a certain treatment effect on common skin diseases such as allergic dermatitis, eczema, mange and the like is achieved, so that the effects of quickly relieving pain and itching are achieved. According to the invention, the honeysuckle flower extract and the wild chrysanthemum flower extract are added into the mosquitocis-free spray, so that the antibacterial, anti-inflammatory and antiviral effects of skin are effectively enhanced, and the composition has the function of absorbing ultraviolet rays and can also have a good skin care effect.

While there have been shown and described what are at present considered the fundamental principles and essential features of the invention and its advantages, it will be apparent to those skilled in the art that the invention is not limited to the details of the foregoing exemplary embodiments, but is capable of other specific forms without departing from the spirit or essential characteristics thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.

Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims (9)

1. The mosquito-repellent spray is characterized in that: comprises the following raw materials in parts by weight: 5-11% of ethanol by mass; 6-10% of polyethylene glycol; 3-5% of lemongrass extract; 4-7% of wormwood extract; 2-4% of honeysuckle flower extract; 3-5% of wild chrysanthemum extract by mass; purified water is 60-75% by mass; 1-2% of modifier and 1-3% of defoaming agent.

2. The mosquito-repellent spray according to claim 1, wherein the spray comprises: comprises the following raw materials in parts by weight: 5% by mass of ethanol; 6% of polyethylene glycol; the mass part of the lemongrass extract is 3 percent; 4% of wormwood extract; 2% of honeysuckle flower extract; 3% of wild chrysanthemum extract by mass; 75% by mass of purified water; 1% by mass of a modifier and 1% by mass of a defoaming agent.

3. The mosquito-repellent spray according to claim 1, wherein the spray comprises: comprises the following raw materials in parts by weight: 8% of ethanol by mass; 7% of polyethylene glycol; the mass part of the lemongrass extract is 4 percent; 6% of wormwood extract; the honeysuckle flower extract accounts for 3 mass percent; the wild chrysanthemum extract accounts for 4 mass percent; 64% by mass of purified water; 2% by mass of a modifier and 2% by mass of a defoaming agent.

4. The preparation method of the mosquito-free spray according to claim 1, which is characterized in that: the preparation steps are as follows:

a. weighing the raw materials in parts by weight;

b. b, after the step a is finished, putting the weighed purified water into a mixer, then adding ethanol, polyethylene glycol, a lemongrass extract, a wormwood extract, a honeysuckle extract and a wild chrysanthemum extract into the mixer for mixing, wherein the rotating speed during mixing is 500-650 r/min, the mixing time is 20-30 min, and the mixing temperature is 40-50 ℃ to prepare a mixture A;

c. after the step B is finished, adding the modifier into the mixture A for mixing, wherein the rotating speed during mixing is 500-650 r/min, the mixing time is 10-15 min, and the mixing temperature is 30-60 ℃ to obtain a mixture B;

d. after the step C is finished, adding a defoaming agent into the mixture B for mixing to obtain a mixture C;

e. after the step d is finished, filtering, standing and sterilizing the mixed mixture C to prepare the mosquito-free spraying agent;

f. and e, after the step e is finished, finally canning and boxing the prepared mosquito-free spraying agent.

5. The method for preparing a mosquito-free spray according to claim 4, which is characterized in that: the modifier is one or more aqueous solutions of ethylene diamine tetraacetic acid, polyvinylpyrrolidone, polyvinyl alcohol and silane coupling agent.

6. The method for preparing a mosquito-free spray according to claim 4, which is characterized in that: the defoaming agent is C_8-10Fatty alcohols, C_10-20Saturated fatty acids or silicone oil.

7. The method for preparing a mosquito-free spray according to claim 4, which is characterized in that: and e, filtering, standing and sterilizing the mixture C in the step e, wherein the mixture C is filtered by an ultrafiltration membrane for 2-3 times, and the standing time is 50-70 min.

8. The method for preparing a mosquito-free spray according to claim 4, which is characterized in that: and e, canning and boxing the mosquito-repellent spray in the step e, wherein each box contains 12 bottles of 60 ml.

9. The method for preparing a mosquito-free spray according to claim 4, which is characterized in that: the preparation steps of the wormwood extract are as follows:

s1, adding petroleum ether with a fixed boiling range into crushed folium artemisiae argyi according to a material-liquid ratio of 1: 5-1: 8(m/v), fully soaking, extracting under the assistance of ultrasound, separating a solid phase from a liquid phase after extraction is finished, wherein the solid phase is the crushed folium artemisiae argyi;

s2, taking a solid phase, repeating the steps for a plurality of times of soaking, extracting for 2-3 times, separating to obtain degreased folium artemisiae argyi, extracting the degreased folium artemisiae argyi for three times by using 90-95% ethanol according to a material-liquid ratio under the assistance of ultrasound, combining extracting solutions obtained by three times of extraction, filtering the extracting solutions, and concentrating the extracting solutions to a certain proportion by using a rotary evaporator to obtain a concentrated solution;

s3, fully mixing the prepared concentrated solution with distilled water according to the volume ratio of 1: 3-5 to obtain a mixed solution, putting the mixed solution into a high-speed centrifuge, and collecting supernatant after centrifugation is finished;

and S4, finally, filtering the collected supernatant, freezing for a period of time, and removing water to obtain the non-volatile folium artemisiae argyi extract.