CN113350467B - Traditional Chinese medicine composition for treating diabetic peripheral vasculopathy and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating diabetic peripheral vasculopathy and preparation method thereof Download PDFInfo
- Publication number
- CN113350467B CN113350467B CN202110830240.4A CN202110830240A CN113350467B CN 113350467 B CN113350467 B CN 113350467B CN 202110830240 A CN202110830240 A CN 202110830240A CN 113350467 B CN113350467 B CN 113350467B
- Authority
- CN
- China
- Prior art keywords
- parts
- dry powder
- extract
- traditional chinese
- chinese medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000003814 drug Substances 0.000 title claims abstract description 110
- 239000000203 mixture Substances 0.000 title claims abstract description 104
- 206010012601 diabetes mellitus Diseases 0.000 title claims abstract description 86
- 238000002360 preparation method Methods 0.000 title claims abstract description 17
- 230000002093 peripheral effect Effects 0.000 title claims description 75
- 210000004369 blood Anatomy 0.000 claims abstract description 58
- 239000008280 blood Substances 0.000 claims abstract description 58
- 230000017531 blood circulation Effects 0.000 claims abstract description 50
- 230000001737 promoting effect Effects 0.000 claims abstract description 48
- 244000144730 Amygdalus persica Species 0.000 claims abstract description 46
- 235000006040 Prunus persica var persica Nutrition 0.000 claims abstract description 46
- 210000000952 spleen Anatomy 0.000 claims abstract description 46
- 210000002784 stomach Anatomy 0.000 claims abstract description 45
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims abstract description 40
- 244000303040 Glycyrrhiza glabra Species 0.000 claims abstract description 40
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 claims abstract description 38
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims abstract description 37
- 235000011477 liquorice Nutrition 0.000 claims abstract description 37
- 238000010792 warming Methods 0.000 claims abstract description 37
- 235000003181 Panax pseudoginseng Nutrition 0.000 claims abstract description 34
- 244000131316 Panax pseudoginseng Species 0.000 claims abstract description 34
- 241000427159 Achyranthes Species 0.000 claims abstract description 31
- 244000061520 Angelica archangelica Species 0.000 claims abstract description 26
- 244000223760 Cinnamomum zeylanicum Species 0.000 claims abstract description 26
- 235000001287 Guettarda speciosa Nutrition 0.000 claims abstract description 26
- 235000017803 cinnamon Nutrition 0.000 claims abstract description 26
- 235000003255 Carthamus tinctorius Nutrition 0.000 claims abstract description 22
- 244000020518 Carthamus tinctorius Species 0.000 claims abstract description 22
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims abstract description 18
- 239000000843 powder Substances 0.000 claims description 360
- 239000000284 extract Substances 0.000 claims description 241
- 244000132619 red sage Species 0.000 claims description 37
- 229940119485 safflower extract Drugs 0.000 claims description 25
- 230000003213 activating effect Effects 0.000 claims description 24
- 235000000485 Smilax china Nutrition 0.000 claims description 23
- 235000003205 Smilax rotundifolia Nutrition 0.000 claims description 23
- 240000009022 Smilax rotundifolia Species 0.000 claims description 23
- 235000020230 cinnamon extract Nutrition 0.000 claims description 21
- 241000382455 Angelica sinensis Species 0.000 claims description 18
- 235000008599 Poria cocos Nutrition 0.000 claims description 16
- 244000197580 Poria cocos Species 0.000 claims description 16
- 240000000031 Achyranthes bidentata Species 0.000 claims description 15
- 235000003889 Paeonia suffruticosa Nutrition 0.000 claims description 12
- 240000005001 Paeonia suffruticosa Species 0.000 claims description 12
- 241000180649 Panax notoginseng Species 0.000 claims description 12
- 235000003143 Panax notoginseng Nutrition 0.000 claims description 12
- 238000002156 mixing Methods 0.000 claims description 8
- 240000007164 Salvia officinalis Species 0.000 claims description 6
- 235000013399 edible fruits Nutrition 0.000 claims description 6
- 235000005412 red sage Nutrition 0.000 claims description 6
- 241001127714 Amomum Species 0.000 claims description 5
- 238000010025 steaming Methods 0.000 claims description 5
- 239000001649 glycyrrhiza glabra l. absolute Substances 0.000 claims description 4
- 229940051810 licorice root extract Drugs 0.000 claims description 4
- 235000020725 licorice root extract Nutrition 0.000 claims description 4
- 244000037364 Cinnamomum aromaticum Species 0.000 claims description 3
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims description 3
- 235000017443 Hedysarum boreale Nutrition 0.000 claims description 2
- 235000007858 Hedysarum occidentale Nutrition 0.000 claims description 2
- 239000001947 glycyrrhiza glabra rhizome/root Substances 0.000 claims description 2
- 239000002994 raw material Substances 0.000 claims description 2
- 244000261559 Smilax china Species 0.000 claims 8
- 238000004806 packaging method and process Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 47
- 208000013600 Diabetic vascular disease Diseases 0.000 abstract description 18
- 230000007774 longterm Effects 0.000 abstract description 14
- 231100000331 toxic Toxicity 0.000 abstract description 9
- 230000002588 toxic effect Effects 0.000 abstract description 9
- 206010067484 Adverse reaction Diseases 0.000 abstract description 7
- 208000018262 Peripheral vascular disease Diseases 0.000 abstract description 7
- 230000006838 adverse reaction Effects 0.000 abstract description 7
- 244000269722 Thea sinensis Species 0.000 abstract description 6
- 229940079593 drug Drugs 0.000 abstract description 4
- 235000014347 soups Nutrition 0.000 abstract description 4
- 241000304195 Salvia miltiorrhiza Species 0.000 abstract description 2
- 235000021058 soft food Nutrition 0.000 description 22
- 235000012054 meals Nutrition 0.000 description 21
- 244000281702 Dioscorea villosa Species 0.000 description 19
- 235000013305 food Nutrition 0.000 description 15
- 240000007594 Oryza sativa Species 0.000 description 13
- 235000007164 Oryza sativa Nutrition 0.000 description 13
- 208000002193 Pain Diseases 0.000 description 13
- 235000009566 rice Nutrition 0.000 description 13
- 108010074051 C-Reactive Protein Proteins 0.000 description 11
- 102100032752 C-reactive protein Human genes 0.000 description 11
- 239000002344 surface layer Substances 0.000 description 11
- 230000006872 improvement Effects 0.000 description 10
- 239000010410 layer Substances 0.000 description 10
- 238000012360 testing method Methods 0.000 description 10
- 235000009917 Crataegus X brevipes Nutrition 0.000 description 9
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 description 9
- 235000009685 Crataegus X maligna Nutrition 0.000 description 9
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 description 9
- 235000009486 Crataegus bullatus Nutrition 0.000 description 9
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 description 9
- 235000009682 Crataegus limnophila Nutrition 0.000 description 9
- 240000000171 Crataegus monogyna Species 0.000 description 9
- 235000004423 Crataegus monogyna Nutrition 0.000 description 9
- 235000002313 Crataegus paludosa Nutrition 0.000 description 9
- 235000009840 Crataegus x incaedua Nutrition 0.000 description 9
- 244000062793 Sorghum vulgare Species 0.000 description 9
- 238000001125 extrusion Methods 0.000 description 9
- 230000006870 function Effects 0.000 description 9
- 235000019713 millet Nutrition 0.000 description 9
- 244000105624 Arachis hypogaea Species 0.000 description 8
- 235000005686 eating Nutrition 0.000 description 8
- 230000003203 everyday effect Effects 0.000 description 8
- 210000003414 extremity Anatomy 0.000 description 8
- 235000020232 peanut Nutrition 0.000 description 8
- 239000011159 matrix material Substances 0.000 description 7
- 244000141331 Amomum villosum Species 0.000 description 6
- 235000003434 Sesamum indicum Nutrition 0.000 description 6
- 244000040738 Sesamum orientale Species 0.000 description 6
- 238000010586 diagram Methods 0.000 description 6
- 239000011859 microparticle Substances 0.000 description 6
- 239000000047 product Substances 0.000 description 6
- 235000019640 taste Nutrition 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 235000002566 Capsicum Nutrition 0.000 description 5
- 235000002722 Dioscorea batatas Nutrition 0.000 description 5
- 235000006536 Dioscorea esculenta Nutrition 0.000 description 5
- 240000001811 Dioscorea oppositifolia Species 0.000 description 5
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 description 5
- 241000736199 Paeonia Species 0.000 description 5
- 235000006484 Paeonia officinalis Nutrition 0.000 description 5
- 239000006002 Pepper Substances 0.000 description 5
- 235000016761 Piper aduncum Nutrition 0.000 description 5
- 240000003889 Piper guineense Species 0.000 description 5
- 235000017804 Piper guineense Nutrition 0.000 description 5
- 235000008184 Piper nigrum Nutrition 0.000 description 5
- 230000009286 beneficial effect Effects 0.000 description 5
- 235000004879 dioscorea Nutrition 0.000 description 5
- 240000006108 Allium ampeloprasum Species 0.000 description 4
- 235000005254 Allium ampeloprasum Nutrition 0.000 description 4
- 235000000832 Ayote Nutrition 0.000 description 4
- 244000306301 Caesalpinia sappan Species 0.000 description 4
- 235000015162 Caesalpinia sappan Nutrition 0.000 description 4
- 241000218176 Corydalis Species 0.000 description 4
- 235000009854 Cucurbita moschata Nutrition 0.000 description 4
- 235000009804 Cucurbita pepo subsp pepo Nutrition 0.000 description 4
- 239000004278 EU approved seasoning Substances 0.000 description 4
- 241000628997 Flos Species 0.000 description 4
- 210000004204 blood vessel Anatomy 0.000 description 4
- 230000001276 controlling effect Effects 0.000 description 4
- 238000013461 design Methods 0.000 description 4
- 235000015177 dried meat Nutrition 0.000 description 4
- 235000011194 food seasoning agent Nutrition 0.000 description 4
- 230000001976 improved effect Effects 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 235000013372 meat Nutrition 0.000 description 4
- 231100000862 numbness Toxicity 0.000 description 4
- 235000015136 pumpkin Nutrition 0.000 description 4
- 230000002829 reductive effect Effects 0.000 description 4
- 244000291564 Allium cepa Species 0.000 description 3
- 235000003717 Boswellia sacra Nutrition 0.000 description 3
- 235000012035 Boswellia serrata Nutrition 0.000 description 3
- 240000007551 Boswellia serrata Species 0.000 description 3
- 206010006784 Burning sensation Diseases 0.000 description 3
- 241001107116 Castanospermum australe Species 0.000 description 3
- 241000218158 Clematis Species 0.000 description 3
- 240000007311 Commiphora myrrha Species 0.000 description 3
- 235000006965 Commiphora myrrha Nutrition 0.000 description 3
- 240000004244 Cucurbita moschata Species 0.000 description 3
- 240000001008 Dimocarpus longan Species 0.000 description 3
- 235000000235 Euphoria longan Nutrition 0.000 description 3
- 240000006927 Foeniculum vulgare Species 0.000 description 3
- 235000004204 Foeniculum vulgare Nutrition 0.000 description 3
- 239000004863 Frankincense Substances 0.000 description 3
- 108010010803 Gelatin Proteins 0.000 description 3
- 208000004044 Hypesthesia Diseases 0.000 description 3
- 235000007265 Myrrhis odorata Nutrition 0.000 description 3
- 244000223014 Syzygium aromaticum Species 0.000 description 3
- 235000016639 Syzygium aromaticum Nutrition 0.000 description 3
- 235000006886 Zingiber officinale Nutrition 0.000 description 3
- 244000273928 Zingiber officinale Species 0.000 description 3
- 210000003423 ankle Anatomy 0.000 description 3
- 210000001367 artery Anatomy 0.000 description 3
- 235000021279 black bean Nutrition 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- 238000005520 cutting process Methods 0.000 description 3
- 229920000159 gelatin Polymers 0.000 description 3
- 239000008273 gelatin Substances 0.000 description 3
- 235000019322 gelatine Nutrition 0.000 description 3
- 235000011852 gelatine desserts Nutrition 0.000 description 3
- 235000008397 ginger Nutrition 0.000 description 3
- 208000034783 hypoesthesia Diseases 0.000 description 3
- 210000003141 lower extremity Anatomy 0.000 description 3
- 239000006187 pill Substances 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 235000010167 Allium cepa var aggregatum Nutrition 0.000 description 2
- 235000008499 Canella winterana Nutrition 0.000 description 2
- 244000080208 Canella winterana Species 0.000 description 2
- 241000282461 Canis lupus Species 0.000 description 2
- 240000004160 Capsicum annuum Species 0.000 description 2
- 208000017667 Chronic Disease Diseases 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 206010017711 Gangrene Diseases 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 206010022562 Intermittent claudication Diseases 0.000 description 2
- 241000212322 Levisticum officinale Species 0.000 description 2
- 241000112528 Ligusticum striatum Species 0.000 description 2
- 235000010617 Phaseolus lunatus Nutrition 0.000 description 2
- 244000100170 Phaseolus lunatus Species 0.000 description 2
- 208000025865 Ulcer Diseases 0.000 description 2
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 2
- KGEKLUUHTZCSIP-HOSYDEDBSA-N [(1s,4s,6r)-1,7,7-trimethyl-6-bicyclo[2.2.1]heptanyl] acetate Chemical compound C1C[C@]2(C)[C@H](OC(=O)C)C[C@H]1C2(C)C KGEKLUUHTZCSIP-HOSYDEDBSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 238000007605 air drying Methods 0.000 description 2
- 230000037208 balanced nutrition Effects 0.000 description 2
- 235000019046 balanced nutrition Nutrition 0.000 description 2
- 235000015895 biscuits Nutrition 0.000 description 2
- 210000002302 brachial artery Anatomy 0.000 description 2
- CRPUJAZIXJMDBK-UHFFFAOYSA-N camphene Chemical compound C1CC2C(=C)C(C)(C)C1C2 CRPUJAZIXJMDBK-UHFFFAOYSA-N 0.000 description 2
- 229940017545 cinnamon bark Drugs 0.000 description 2
- 239000013065 commercial product Substances 0.000 description 2
- 238000002591 computed tomography Methods 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000002349 favourable effect Effects 0.000 description 2
- 238000007667 floating Methods 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 235000013402 health food Nutrition 0.000 description 2
- 238000003384 imaging method Methods 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 208000021156 intermittent vascular claudication Diseases 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 239000001645 levisticum officinale Substances 0.000 description 2
- 230000000670 limiting effect Effects 0.000 description 2
- XMGQYMWWDOXHJM-UHFFFAOYSA-N limonene Chemical compound CC(=C)C1CCC(C)=CC1 XMGQYMWWDOXHJM-UHFFFAOYSA-N 0.000 description 2
- CDOSHBSSFJOMGT-UHFFFAOYSA-N linalool Chemical compound CC(C)=CCCC(C)(O)C=C CDOSHBSSFJOMGT-UHFFFAOYSA-N 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 230000000284 resting effect Effects 0.000 description 2
- 239000004576 sand Substances 0.000 description 2
- 210000000582 semen Anatomy 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 235000000346 sugar Nutrition 0.000 description 2
- 230000009747 swallowing Effects 0.000 description 2
- 230000035488 systolic blood pressure Effects 0.000 description 2
- 210000002465 tibial artery Anatomy 0.000 description 2
- 229940034610 toothpaste Drugs 0.000 description 2
- 239000000606 toothpaste Substances 0.000 description 2
- 229940126680 traditional chinese medicines Drugs 0.000 description 2
- 231100000216 vascular lesion Toxicity 0.000 description 2
- 239000000811 xylitol Substances 0.000 description 2
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 2
- 229960002675 xylitol Drugs 0.000 description 2
- 235000010447 xylitol Nutrition 0.000 description 2
- SDOFMBGMRVAJNF-KVTDHHQDSA-N (2r,3r,4r,5r)-6-aminohexane-1,2,3,4,5-pentol Chemical compound NC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO SDOFMBGMRVAJNF-KVTDHHQDSA-N 0.000 description 1
- 239000001490 (3R)-3,7-dimethylocta-1,6-dien-3-ol Substances 0.000 description 1
- KJPRLNWUNMBNBZ-QPJJXVBHSA-N (E)-cinnamaldehyde Chemical compound O=C\C=C\C1=CC=CC=C1 KJPRLNWUNMBNBZ-QPJJXVBHSA-N 0.000 description 1
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 description 1
- CDOSHBSSFJOMGT-JTQLQIEISA-N (R)-linalool Natural products CC(C)=CCC[C@@](C)(O)C=C CDOSHBSSFJOMGT-JTQLQIEISA-N 0.000 description 1
- WTPPRJKFRFIQKT-UHFFFAOYSA-N 1,6-dimethyl-8,9-dihydronaphtho[1,2-g][1]benzofuran-10,11-dione;1-methyl-6-methylidene-8,9-dihydro-7h-naphtho[1,2-g][1]benzofuran-10,11-dione Chemical compound O=C1C(=O)C2=C3CCCC(=C)C3=CC=C2C2=C1C(C)=CO2.O=C1C(=O)C2=C3CCC=C(C)C3=CC=C2C2=C1C(C)=CO2 WTPPRJKFRFIQKT-UHFFFAOYSA-N 0.000 description 1
- WEEGYLXZBRQIMU-UHFFFAOYSA-N 1,8-cineole Natural products C1CC2CCC1(C)OC2(C)C WEEGYLXZBRQIMU-UHFFFAOYSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- JRJGKUTZNBZHNK-UHFFFAOYSA-N 3-phenylpropyl acetate Chemical compound CC(=O)OCCCC1=CC=CC=C1 JRJGKUTZNBZHNK-UHFFFAOYSA-N 0.000 description 1
- HOMSOWZTBJWNHP-UHFFFAOYSA-N 5-chlorothiadiazole Chemical compound ClC1=CN=NS1 HOMSOWZTBJWNHP-UHFFFAOYSA-N 0.000 description 1
- 201000004384 Alopecia Diseases 0.000 description 1
- 241000219317 Amaranthaceae Species 0.000 description 1
- 235000011446 Amygdalus persica Nutrition 0.000 description 1
- 241000208173 Apiaceae Species 0.000 description 1
- 241000208340 Araliaceae Species 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 241000208838 Asteraceae Species 0.000 description 1
- 238000008645 C-Reactive Protein (CRP) Assay Methods 0.000 description 1
- 235000008534 Capsicum annuum var annuum Nutrition 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 206010010356 Congenital anomaly Diseases 0.000 description 1
- 235000014493 Crataegus Nutrition 0.000 description 1
- 241001092040 Crataegus Species 0.000 description 1
- 241000219122 Cucurbita Species 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 208000008960 Diabetic foot Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- WEEGYLXZBRQIMU-WAAGHKOSSA-N Eucalyptol Chemical compound C1C[C@H]2CC[C@]1(C)OC2(C)C WEEGYLXZBRQIMU-WAAGHKOSSA-N 0.000 description 1
- 241000220485 Fabaceae Species 0.000 description 1
- 241000202807 Glycyrrhiza Species 0.000 description 1
- 241001278898 Glycyrrhiza inflata Species 0.000 description 1
- 235000000554 Glycyrrhiza uralensis Nutrition 0.000 description 1
- 240000008917 Glycyrrhiza uralensis Species 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 241000207923 Lamiaceae Species 0.000 description 1
- 241000218195 Lauraceae Species 0.000 description 1
- 229920000715 Mucilage Polymers 0.000 description 1
- 206010028851 Necrosis Diseases 0.000 description 1
- 206010034568 Peripheral coldness Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- PXRCIOIWVGAZEP-UHFFFAOYSA-N Primaeres Camphenhydrat Natural products C1CC2C(O)(C)C(C)(C)C1C2 PXRCIOIWVGAZEP-UHFFFAOYSA-N 0.000 description 1
- 235000015533 Prunus davidiana Nutrition 0.000 description 1
- 240000002381 Prunus davidiana Species 0.000 description 1
- 240000005809 Prunus persica Species 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 241000218201 Ranunculaceae Species 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 235000004789 Rosa xanthina Nutrition 0.000 description 1
- 241000220222 Rosaceae Species 0.000 description 1
- 241000612118 Samolus valerandi Species 0.000 description 1
- 239000009759 San-Chi Substances 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 241000234299 Zingiberaceae Species 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- XCPQUQHBVVXMRQ-UHFFFAOYSA-N alpha-Fenchene Natural products C1CC2C(=C)CC1C2(C)C XCPQUQHBVVXMRQ-UHFFFAOYSA-N 0.000 description 1
- 238000002266 amputation Methods 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000002583 angiography Methods 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 229940115397 bornyl acetate Drugs 0.000 description 1
- 235000008429 bread Nutrition 0.000 description 1
- 229930006739 camphene Natural products 0.000 description 1
- ZYPYEBYNXWUCEA-UHFFFAOYSA-N camphenilone Natural products C1CC2C(=O)C(C)(C)C1C2 ZYPYEBYNXWUCEA-UHFFFAOYSA-N 0.000 description 1
- 239000010238 camphora Substances 0.000 description 1
- 229940025250 camphora Drugs 0.000 description 1
- 239000001511 capsicum annuum Substances 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 229960005233 cineole Drugs 0.000 description 1
- KJPRLNWUNMBNBZ-UHFFFAOYSA-N cinnamic aldehyde Natural products O=CC=CC1=CC=CC=C1 KJPRLNWUNMBNBZ-UHFFFAOYSA-N 0.000 description 1
- 229940117916 cinnamic aldehyde Drugs 0.000 description 1
- WJSDHUCWMSHDCR-VMPITWQZSA-N cinnamyl acetate Natural products CC(=O)OC\C=C\C1=CC=CC=C1 WJSDHUCWMSHDCR-VMPITWQZSA-N 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 235000021551 crystal sugar Nutrition 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 235000006694 eating habits Nutrition 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 210000002683 foot Anatomy 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 208000024963 hair loss Diseases 0.000 description 1
- 230000003676 hair loss Effects 0.000 description 1
- 239000011796 hollow space material Substances 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- LTINPJMVDKPJJI-UHFFFAOYSA-N iodinated glycerol Chemical compound CC(I)C1OCC(CO)O1 LTINPJMVDKPJJI-UHFFFAOYSA-N 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 229940087305 limonene Drugs 0.000 description 1
- 235000001510 limonene Nutrition 0.000 description 1
- 229930007744 linalool Natural products 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 208000030212 nutrition disease Diseases 0.000 description 1
- 208000019180 nutritional disease Diseases 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- VDYCLYGKCGVBHN-UHFFFAOYSA-N pachymaic acid Natural products CC12CCC(OC(C)=O)C(C)(C)C1CCC1=C2CCC2(C)C(C(CCC(=C)C(C)C)C(O)=O)C(O)CC21C VDYCLYGKCGVBHN-UHFFFAOYSA-N 0.000 description 1
- SRDNLMOBFKJOSD-UHFFFAOYSA-N pachymic acid Natural products CC12CCC(OC(C)=O)C(C)(C)C1CCC1=C2CCC2(C)C(C(CCC=C(C)C)C(O)=O)C(O)CC21C SRDNLMOBFKJOSD-UHFFFAOYSA-N 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 208000030613 peripheral artery disease Diseases 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 238000000053 physical method Methods 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000010349 pulsation Effects 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000000171 quenching effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000036186 satiety Effects 0.000 description 1
- 235000019627 satiety Nutrition 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 235000018553 tannin Nutrition 0.000 description 1
- 229920001864 tannin Polymers 0.000 description 1
- 239000001648 tannin Substances 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 230000036269 ulceration Effects 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/235—Foeniculum (fennel)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/716—Clematis (leather flower)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9064—Amomum, e.g. round cardamom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Developmental Biology & Embryology (AREA)
- Emergency Medicine (AREA)
- Virology (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The application relates to a traditional Chinese medicine composition for treating diabetic peripheral vascular disease and a preparation method thereof, wherein the traditional Chinese medicine composition for treating diabetic peripheral vascular disease comprises the following components: spleen and stomach tonifying component, blood circulation promoting and collateral dredging component, yang warming and cold dispelling component, and blood replenishing and blood circulation promoting component; the composition comprises the following components in parts by weight: 5 to 10 parts of white poria, 5 to 10 parts of fructus amomi, 2 to 5 parts of moutan bark, 2 to 5 parts of peach kernel, 2 to 5 parts of safflower, 3 to 7 parts of achyranthes root, 2 to 5 parts of cinnamon, 5 to 10 parts of salvia miltiorrhiza, 3 to 7 parts of pseudo-ginseng, 1 to 5 parts of liquorice and 2 to 5 parts of angelica. The traditional Chinese medicine composition is pure traditional Chinese medicine components, does not contain any western medicine components, is prepared from all medicines which are safe and available for human bodies, adopts elaborate optimized proportion, has no toxic or side effect and adverse reaction, can be prepared into soup or tea or directly taken, has better effect on treating peripheral vascular diseases of diabetes, and is particularly suitable for long-term taking of diabetics.
Description
Technical Field
The application relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating diabetic peripheral vascular disease and a preparation method thereof.
Background
Diabetes mellitus is a chronic disease with a high incidence rate, and is also called a rich disease. Clinically, diabetes is classified into two types, one type of diabetes and one type of diabetes. Type one diabetes is primary diabetes, which is congenital to some extent, and is related to heredity; more than ninety percent of clinically common types of diabetes are type II diabetes, which is mainly related to acquired dietary habits and the like.
Diabetes causes numerous complications, most notably damage to the organs involved, and more seriously damage results in lesions of autologous peripheral vessels, also known as peripheral vascular lesions, which cause rough narrowing or even occlusion of the peripheral vessels, resulting in impaired blood supply to the extremities. For example, gangrene necrosis of blood vessels in diabetic feet can cause cold feet, thin nails and easy ulceration due to hair loss of the feet of patients.
However, there is a lack of effective therapeutic compositions of pure traditional Chinese medicines for peripheral vascular disease.
Disclosure of Invention
Therefore, a traditional Chinese medicine composition for treating diabetic peripheral vascular diseases and a preparation method thereof are needed.
A Chinese medicinal composition for treating diabetic peripheral vasculopathy, comprising: spleen and stomach tonifying components, blood circulation promoting and collateral dredging components, yang warming and cold dispelling components, and blood replenishing and blood circulation promoting components; according to the mass portion of the raw materials,
the spleen and stomach tonifying components comprise the following components: 5 to 10 portions of white poria and 5 to 10 portions of fructus amomi;
the blood circulation promoting and collateral dredging component comprises the following components: 2 to 5 parts of tree peony bark, 2 to 5 parts of peach seed and 2 to 5 parts of safflower;
the yang warming and cold dispelling components comprise the following components: 3 to 7 parts of achyranthes and 2 to 5 parts of cinnamon;
the blood replenishing and activating components comprise the following components: 5 to 10 portions of salvia miltiorrhiza, 3 to 7 portions of panax notoginseng, 1 to 5 portions of liquorice and 2 to 5 portions of angelica.
The traditional Chinese medicine composition is pure traditional Chinese medicine components, does not contain any western medicine components, is prepared from all medicines which are safe and available for human bodies, adopts elaborate optimized proportion, has no toxic or side effect and adverse reaction, can be prepared into soup or tea or directly taken, has better effect on treating peripheral vascular diseases of diabetes, and is particularly suitable for long-term taking of diabetics.
In other embodiments, the product can be used as a substitute for meal, and can be massively used for a long time due to no toxic or side effect and adverse reaction.
In one embodiment, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by weight: 5 to 10 parts of chinaroot greenbrier rhizome extract, 5 to 10 parts of fructus amomi extract, 2 to 5 parts of tree peony bark extract, 2 to 5 parts of peach kernel extract, 2 to 5 parts of safflower extract, 3 to 7 parts of twotooth achyranthes root extract, 2 to 5 parts of cinnamon extract, 5 to 10 parts of red sage root extract, 3 to 7 parts of pseudo-ginseng extract, 1 to 5 parts of liquorice extract and 2 to 5 parts of Chinese angelica extract; or 5 to 10 parts of white poria dry powder, 5 to 10 parts of fructus amomi dry powder, 2 to 5 parts of cortex moutan dry powder, 2 to 5 parts of peach kernel dry powder, 2 to 5 parts of safflower dry powder, 3 to 7 parts of achyranthes root dry powder, 2 to 5 parts of cinnamon dry powder, 5 to 10 parts of salvia miltiorrhiza dry powder, 3 to 7 parts of pseudo-ginseng dry powder, 1 to 5 parts of liquorice dry powder and 2 to 5 parts of angelica sinensis dry powder.
In one embodiment, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by mass: 6 to 9 parts of chinaroot greenbrier rhizome extract or dry powder, 6 to 9 parts of villous amomum fruit extract or dry powder, 3 to 4 parts of tree peony bark extract or dry powder, 3 to 4 parts of peach kernel extract or dry powder, 3 to 4 parts of safflower extract or dry powder, 4 to 6 parts of twotooth achyranthes root extract or dry powder, 3 to 4 parts of cassia bark extract or dry powder, 6 to 9 parts of red sage root extract or dry powder, 4 to 6 parts of pseudo-ginseng extract or dry powder, 2 to 4 parts of licorice root extract or dry powder and 3 to 4 parts of Chinese angelica extract or dry powder.
In one embodiment, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by mass: 10 parts of chinaroot greenbrier rhizome extract or dry powder, 5 parts of fructus amomi extract or dry powder, 2 parts of cortex moutan extract or dry powder, 5 parts of peach kernel extract or dry powder, 2 parts of safflower extract or dry powder, 7 parts of achyranthes bidentata extract or dry powder, 2 parts of cinnamon extract or dry powder, 10 parts of salvia miltiorrhiza extract or dry powder, 3 parts of pseudo-ginseng extract or dry powder, 5 parts of liquorice extract or dry powder and 2 parts of angelica extract or dry powder; or 5 parts of chinaroot greenbrier rhizome extract or dry powder, 10 parts of fructus amomi extract or dry powder, 5 parts of cortex moutan extract or dry powder, 2 parts of peach kernel extract or dry powder, 2 parts of safflower extract or dry powder, 3 parts of achyranthes root extract or dry powder, 5 parts of cinnamon extract or dry powder, 5 parts of salvia miltiorrhiza extract or dry powder, 7 parts of pseudo-ginseng extract or dry powder, 1 part of liquorice extract or dry powder and 5 parts of angelica extract or dry powder; or 6 parts of chinaroot greenbrier rhizome extract or dry powder, 9 parts of fructus amomi extract or dry powder, 4 parts of cortex moutan extract or dry powder, 3 parts of peach kernel extract or dry powder, 4 parts of safflower extract or dry powder, 4 parts of achyranthes bidentata extract or dry powder, 4 parts of cinnamon extract or dry powder, 6 parts of salvia miltiorrhiza extract or dry powder, 6 parts of pseudo-ginseng extract or dry powder, 2 parts of liquorice extract or dry powder and 4 parts of angelica extract or dry powder; or, poria cocos wolf extract or dry powder 9 parts, amomum villosum extract or dry powder 6 parts, moutan bark extract or dry powder 3 parts, peach kernel extract or dry powder 4 parts, safflower extract or dry powder 3 parts, achyranthes bidentata extract or dry powder 6 parts, cinnamon extract or dry powder 3 parts, salvia miltiorrhiza extract or dry powder 9 parts, notoginseng extract or dry powder 4 parts, licorice root extract or dry powder 4 parts, and angelica sinensis extract or dry powder 3 parts; or 8 parts of chinaroot greenbrier rhizome extract or dry powder, 7 parts of fructus amomi extract or dry powder, 4 parts of cortex moutan extract or dry powder, 3 parts of peach kernel extract or dry powder, 3 parts of safflower extract or dry powder, 6 parts of achyranthes bidentata extract or dry powder, 4 parts of cinnamon extract or dry powder, 9 parts of salvia miltiorrhiza extract or dry powder, 5 parts of pseudo-ginseng extract or dry powder, 2 parts of liquorice extract or dry powder and 4 parts of angelica extract or dry powder; or 7 parts of chinaroot greenbrier rhizome extract or dry powder, 7 parts of fructus amomi extract or dry powder, 3 parts of cortex moutan extract or dry powder, 3 parts of peach kernel extract or dry powder, 3 parts of safflower extract or dry powder, 5 parts of achyranthes root extract or dry powder, 3 parts of cinnamon extract or dry powder, 8 parts of salvia miltiorrhiza extract or dry powder, 5 parts of pseudo-ginseng extract or dry powder, 3 parts of liquorice extract or dry powder and 3 parts of angelica extract or dry powder.
In one embodiment, in the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy, the spleen and stomach tonifying components further comprise the following components in parts by mass: at least one of 5 to 25 parts of glutinous rice and 5 to 15 parts of peanuts; and/or the blood circulation promoting and collateral dredging component further comprises the following components in parts by weight: at least one of 2 to 5 parts of corydalis tuber, 1 to 5 parts of szechuan lovage rhizome and 1 to 3 parts of sappan wood.
In one embodiment, the ratio of the spleen and stomach tonifying component, the blood activating and collateral dredging component, the yang warming and cold dispelling component and the blood replenishing and activating component in parts by mass is A: B: C: D; wherein A is 4 to 8, B is 3 to 5, C is 3 to 5, and D is 6 to 10.
In one embodiment, A is 6, B is 4, C is 4, D is 8; and/or, according to the mass parts, the white poria cocos is the same as the fructus amomi, the moutan bark and the peach kernel are the same as the safflower, the proportion of the achyranthes root to the cinnamon is 2 to 1.
In one embodiment, the spleen and stomach tonifying component further comprises the following components in parts by mass: at least one of 10 to 20 parts of Chinese yam, 2 to 5 parts of red date, 1 to 5 parts of hawthorn and 10 to 20 parts of millet; and/or the blood circulation promoting and collateral dredging component further comprises the following components in parts by weight: at least one of 2 to 4 parts of red peony root, 2 to 5 parts of frankincense, 3 to 5 parts of myrrh and 3 to 6 parts of clematis root; and/or the yang warming and cold dispelling components further comprise the following components in parts by weight: at least one of 1 to 2 parts of shallot, 1 to 10 parts of leek, 1 to 2 parts of ginger, 1 to 2 parts of clove, 1 to 2 parts of pepper, 1 to 2 parts of cinnamon and 1 to 2 parts of fennel; and/or the blood enriching and activating component also comprises the following components in parts by weight: at least one of donkey-hide gelatin 1 to 3 parts, black bean 5 to 10 parts, longan 3 to 7 parts and pumpkin 5 to 10 parts.
In one embodiment, the components are all extracts or all dry powders.
In one embodiment, the preparation method of the traditional Chinese medicine composition for treating diabetic peripheral vascular diseases adopts any one of the traditional Chinese medicine compositions for treating diabetic peripheral vascular diseases, and the traditional Chinese medicine compositions are uniformly mixed, steamed and prepared into soft food.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments or the conventional technologies of the present application, the drawings used in the descriptions of the embodiments or the conventional technologies will be briefly introduced below, it is obvious that the drawings in the following descriptions are only some embodiments of the present application, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
Fig. 1 is a schematic diagram illustrating a mixture ratio of an embodiment of the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy. Fig. 2 is a schematic diagram of another embodiment of a composition of the present application for treating diabetic peripheral vasculopathy. Fig. 3 is a schematic diagram illustrating a mixture ratio of another embodiment of the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy according to the present application. FIG. 4 is a schematic diagram of another embodiment of a composition of the present invention for treating diabetic peripheral vasculopathy. Fig. 5 is a schematic view of another embodiment of a composition of the present application for treating diabetic peripheral vasculopathy. Fig. 6 is a schematic view of another embodiment of a composition of the present application for treating diabetic peripheral vasculopathy. FIG. 7 is a schematic diagram illustrating the formulation of another embodiment of the Chinese medicinal composition for treating diabetic peripheral vasculopathy according to the present application. FIG. 8 is a schematic diagram of another embodiment of a composition of the present invention for treating diabetic peripheral vasculopathy. Fig. 9 is a schematic view of another embodiment of a composition of the present application for treating diabetic peripheral vasculopathy.
Detailed Description
In order to make the aforementioned objects, features and advantages of the present application more comprehensible, embodiments accompanying the present application are described in detail below with reference to the accompanying drawings. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present application. This application is capable of embodiment in many different forms than those described herein and those skilled in the art will be able to make similar modifications without departing from the spirit of the application and therefore the application is not limited to the specific embodiments disclosed below.
It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and the like as used in the description of the present application are for illustrative purposes only and do not represent the only embodiments.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or to implicitly indicate the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present application, "plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.
In this application, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may mean that the first feature is in direct contact with the second feature, or that the first feature and the second feature are in indirect contact via an intermediate. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature "on," "over," and "above" a second feature may be directly or obliquely below the second feature, or simply mean that the first feature is at a lesser elevation than the second feature. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used in the description of the present application is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. As used in the description of the present application, the term "and/or" includes any and all combinations of one or more of the associated listed items.
In one embodiment of the present application, a traditional Chinese medicine composition for treating diabetic peripheral vasculopathy is shown in fig. 1, and comprises components for tonifying spleen and stomach, components for promoting blood circulation and removing obstruction in channels, components for warming yang and dispelling cold, and components for replenishing blood and promoting blood circulation; the spleen and stomach tonifying components comprise the following components in parts by weight: 5 to 10 parts of white poria and 5 to 10 parts of fructus amomi; the blood circulation promoting and collateral dredging component comprises the following components: 2 to 5 parts of tree peony bark, 2 to 5 parts of peach seed and 2 to 5 parts of safflower; the yang warming and cold dispelling components comprise the following components: 3 to 7 parts of achyranthes and 2 to 5 parts of cinnamon; the blood replenishing and activating components comprise the following components: 5 to 10 portions of salvia miltiorrhiza, 3 to 7 portions of panax notoginseng, 1 to 5 portions of liquorice and 2 to 5 portions of angelica. The traditional Chinese medicine composition is pure traditional Chinese medicine components, does not contain any western medicine components, is prepared from all medicines which are safe and available for human bodies, adopts elaborate optimized proportion, has no toxic or side effect and adverse reaction, can be prepared into soup or tea or directly taken, has better effect on treating peripheral vascular diseases of diabetes, and is particularly suitable for long-term taking of diabetics.
In one embodiment, a Chinese medicinal composition for treating diabetic peripheral vasculopathy comprises the following part of or all the components of the embodiment; namely, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following partial technical characteristics or all technical characteristics. In one embodiment, the components are all extracts or all dry powders. In each example, the term "part by mass" means "g, mg, kg, jin, kg, pound, ton, etc. In grams for example, 1 part is a certain mass in the range of 0.0001 to 10000 grams; for example, 1 part may be 0.001g, 0.01g, 0.02g, 0.05g, 0.1g, 0.2g, 0.5g, 1g, 2g, 3g, 4g, 5g, 10g, 15g, 20g, 30g, 50g, 80g, 100g, 500g, 1000g, 5000g, 10000g, 50000g, or the like, and is not limited thereto, and may be selected according to actual production, and so forth in each example. For example, 1 part is 1g, and 0.1 part is 0.1 g; for another example, 1 part is 10g, and 0.1 part is 1 g; for another example, 1 part is 100g, and 0.1 part is 10 g; and so on. In the specific application, the design can be flexibly designed according to actual requirements, and only a certain mass ratio or mass proportion of each component is required to be met, wherein each component comprises but is not limited to white poria, fructus amomi, cortex moutan, peach kernel, safflower, achyranthes, cinnamon, salvia miltiorrhiza, pseudo-ginseng, liquorice, angelica and the like; for example, for embodiments having glutinous rice, then the component further includes glutinous rice. The rest of the embodiments are analogized and are not described in detail. In one embodiment, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by weight: 5 to 10 grams of white poria, 5 to 10 grams of fructus amomi, 2 to 5 grams of moutan bark, 2 to 5 grams of peach kernel, 2 to 5 grams of safflower, 3 to 7 grams of achyranthes, 2 to 5 grams of cinnamon, 5 to 10 grams of salvia miltiorrhiza, 3 to 7 grams of pseudo-ginseng, 1 to 5 grams of liquorice and 2 to 5 grams of angelica, wherein 1 part is 1 gram. The rest embodiments are analogized in this way, and are not described in detail.
In each embodiment, in terms of mechanism of traditional Chinese medicine, the white poria is a white part of a medicinal material poria cocos after cutting red poria cocos, and the white poria cocos contains pachyman, B-pachyman, pachymic acid, lecithin, sterol and the like. Fructus Amomi is fruit of Amomum villosum Bunge, fructus Amomi rotundus Linn or Hainan Sand belonging to genus Amomum of family Zingiberaceae, and contains volatile oil, limonene, linalool, bornyl acetate, camphora, camphene, eucalyptol and flavonoids. Cortex moutan is dry root bark of Paeonia suffruticosa Andr.f. of Ranunculaceae, and has effects of clearing heat and cooling blood, promoting blood circulation and removing blood stasis, and relieving deficiency heat. Semen Persicae is dry mature seed of Prunus persica or Prunus davidiana of Rosaceae, and has effects of promoting blood circulation for removing blood stasis, loosening bowel to relieve constipation, relieving cough and asthma, etc. Carthami flos is dried flower of Carthamus tinctorius L of Compositae, and has effects of promoting blood circulation, dredging channels, removing blood stasis, and relieving pain. Achyranthis radix is the dry root of Achyranthis radix of Amaranthaceae, and has effects of removing blood stasis, dredging channels, nourishing liver and kidney, strengthening tendons and bones, inducing diuresis, treating stranguria, and drawing blood downward. Cinnamon is the dry bark of cinnamon of Lauraceae, which contains 1-2% of cinnamon bark oil, 75-90% of cinnamaldehyde as the main component, and a small amount of cinnamyl acetate, phenylpropyl acetate, mucus, tannin and the like, and has the effects of tonifying yang, warming spleen and stomach, removing cold accumulation, promoting blood circulation and the like. Saviae Miltiorrhizae radix is dried root and rhizome of Salvia miltiorrhiza Bunge of Labiatae, and has effects of promoting blood circulation, removing blood stasis, dredging channels, relieving pain, clearing heart fire, relieving restlessness, cooling blood, and resolving carbuncle. Notoginseng radix is the dry root of Panax notoginseng (Burk.) F.H.Chen of Araliaceae, and has effects of removing blood stasis, stopping bleeding, promoting blood circulation, and relieving pain. The Glycyrrhrizae radix is dried root and rhizome of Glycyrrhiza uralensis Fisch, glycyrrhiza inflata Bat or Glycyrrhiza glabra L of Leguminosae, and has effects of invigorating spleen and qi, clearing away heat and toxic materials, eliminating phlegm and relieving cough, and relieving spasm and pain. Radix Angelicae sinensis is the dried root of Angelica sinensis of Umbelliferae, and has effects of replenishing blood, promoting blood circulation, regulating menstruation, relieving pain, loosening bowel, and relieving constipation. The rest components are analogized in the same way, and are not described in detail, so that the embodiment of the application has no additional limitation.
Further, in one embodiment, the amount of the blood enriching and activating component is greater than that of the spleen and stomach tonifying component, the amount of the spleen and stomach tonifying component is greater than that of the blood invigorating and collateral dredging component and that of the yang warming and cold dispelling component, the amount of the blood invigorating and collateral dredging component is equal to or approximately equal to that of the yang warming and cold dispelling component or the amount of the blood invigorating and collateral dredging component is slightly greater than that of the yang warming and cold dispelling component; in one embodiment, the amount of the blood-activating and collateral-dredging component is 80% to 120% of the amount of the yang-warming and cold-dispelling component. Further, in one embodiment, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises 10-20 parts of spleen and stomach tonifying components, 6-15 parts of blood activating and collateral dredging components, 5-12 parts of yang warming and cold dispelling components and 11-27 parts of blood enriching and blood activating components. In one embodiment, the ratio of the spleen and stomach tonifying component, the blood activating and collateral dredging component, the yang warming and cold dispelling component and the blood replenishing and activating component in parts by mass is A: B: C: D; wherein A is 4 to 8, B is 3 to 5, C is 3 to 5, and D is 6 to 10. In one embodiment, A is from 5 to 7, B is from 3.5 to 4.5, C is from 3.5 to 4.5, and D is from 7 to 9. In one embodiment, A is 6, B is 4, C is 4, D is 8; the ratio of the components for tonifying spleen and stomach, the components for promoting blood circulation and removing obstruction in channels, the components for warming yang and dispelling cold and the components for replenishing blood and promoting blood circulation is (6). The most important invention point of each embodiment of the application is that the monarch and minister proportion of components for tonifying spleen and stomach, components for promoting blood circulation and removing obstruction in channels, components for warming yang and dispelling cold and components for enriching blood and promoting blood circulation is adopted to reasonably restrict peripheral vascular diseases of diabetes, help patients recover and avoid amputation risk. Moreover, for patients with diabetic peripheral vasculopathy, when the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy is selected, the traditional Chinese medicine composition can adopt a general mixture ratio, and can also be distinguished according to the specific conditions of the patients, such as specific conditions of qi deficiency and blood stasis, blood stasis and collateral obstruction, yin deficiency and blood stasis, blood circulation and stasis removal, collateral dredging and pain relieving and the like, so that the specific proportions of components for tonifying spleen and stomach, components for promoting blood circulation and dredging collaterals, components for warming yang and dispelling cold and components for replenishing blood and promoting blood circulation are properly adjusted.
Further, in one embodiment, the poria cocos is the same as the fructus amomi, the moutan bark and the peach kernel are the same as the safflower, and the ratio of the achyranthes bidentata to the cinnamon is 2. Further, in one embodiment, the amounts of Danshen root, sanchi, danggui and Licorice root are decreased sequentially. In one embodiment, the white poria cocos is the same as fructus amomi, the moutan bark and the peach kernel are the same as safflower, the ratio of achyranthes bidentata to cinnamon is 2 to 1. In one embodiment, the ratio of the spleen and stomach tonifying component, the blood activating and collateral dredging component, the yang warming and cold dispelling component and the blood enriching and activating component is 6. The rest embodiments are analogized in this way, and are not described in detail.
In one embodiment, as shown in fig. 2, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by weight: 5 to 10 parts of chinaroot greenbrier rhizome extract, 5 to 10 parts of fructus amomi extract, 2 to 5 parts of tree peony bark extract, 2 to 5 parts of peach kernel extract, 2 to 5 parts of safflower extract, 3 to 7 parts of twotooth achyranthes root extract, 2 to 5 parts of cinnamon extract, 5 to 10 parts of red sage root extract, 3 to 7 parts of pseudo-ginseng extract, 1 to 5 parts of liquorice extract and 2 to 5 parts of Chinese angelica extract; in each example, the white poria extract, i.e., the white poria extract obtained by cutting poria cocos into pieces, can be obtained by making or purchasing commercially available products, and the fructus amomi extract is the extract of the fruits of amomum villosum, amomum villosum or hainan amomum; cortex moutan extract, which is an extract of dried root bark of peony; can be obtained by making or purchasing a commercially available product; the rest components and the rest embodiments are analogized, and the effective parts are extracted according to the needs. It is understood that the extracts described in the present invention and various embodiments thereof, including but not limited to poria cocos wolf extract, amomum villosum extract, moutan bark extract, peach kernel extract, safflower extract, achyranthes bidentata extract, cinnamon bark extract, salvia miltiorrhiza extract, notoginseng extract, glycyrrhiza extract, angelica sinensis extract, etc., may be extracted by using chemical reagents such as aqueous solution, alcohol or ether in combination with physical methods such as pressing, squeezing, extracting, centrifuging or distilling, and the concentration may be adjusted according to needs or experiments. In one embodiment, the components comprise Poria, fructus Amomi, cortex moutan, semen Persicae, carthami flos, achyranthis radix, cortex Cinnamomi, saviae Miltiorrhizae radix, notoginseng radix, glycyrrhrizae radix and radix Angelicae sinensis, and their extracts can be used. That is, the components in the respective examples may be replaced with the corresponding extracts. The rest of the embodiments are analogized and are not described in detail.
Or, in one embodiment, as shown in fig. 3, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by weight: 5 to 10 parts of white poria dry powder, 5 to 10 parts of fructus amomi dry powder, 2 to 5 parts of cortex moutan dry powder, 2 to 5 parts of peach kernel dry powder, 2 to 5 parts of safflower dry powder, 3 to 7 parts of achyranthes root dry powder, 2 to 5 parts of cinnamon dry powder, 5 to 10 parts of salvia miltiorrhiza dry powder, 3 to 7 parts of pseudo-ginseng dry powder, 1 to 5 parts of liquorice dry powder and 2 to 5 parts of angelica sinensis dry powder. Similarly, in each example, the dry powder of white poria, i.e. the dry powder prepared by cutting off the white part of the red poria from the medicinal material poria block, can be obtained by making or purchasing the commercial product, and similarly, the dry powder of fructus amomi is the dry powder of the fruits of amomum villosum, green shell sand or Hainan sand; dry powder of cortex moutan, i.e. dry powder of dry root bark of peony; can be obtained by self-making or purchasing a commercial product; the rest components and the rest examples are analogized, and the effective parts are taken as required to prepare the dry powder. Compared with the embodiment of the extract, the embodiment of the dry powder is beneficial to reducing the cost and is suitable for a large number of consumers.
In one embodiment, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by weight: 6 to 9 parts of chinaroot greenbrier rhizome extract or dry powder, 6 to 9 parts of villous amomum fruit extract or dry powder, 3 to 4 parts of tree peony bark extract or dry powder, 3 to 4 parts of peach kernel extract or dry powder, 3 to 4 parts of safflower extract or dry powder, 4 to 6 parts of twotooth achyranthes root extract or dry powder, 3 to 4 parts of cassia bark extract or dry powder, 6 to 9 parts of red sage root extract or dry powder, 4 to 6 parts of pseudo-ginseng extract or dry powder, 2 to 4 parts of licorice root extract or dry powder and 3 to 4 parts of Chinese angelica extract or dry powder. In one embodiment, in the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy, the spleen and stomach tonifying components further comprise the following components in parts by mass: at least one of 5 to 25 parts of glutinous rice and 5 to 15 parts of peanuts; for example, a Chinese medicinal composition for treating diabetic peripheral vascular disease comprises: spleen and stomach tonifying component, blood circulation promoting and collateral dredging component, yang warming and cold dispelling component, and blood replenishing and blood circulation promoting component; the spleen and stomach tonifying components comprise the following components in parts by weight: 5 to 10 parts of white poria and 5 to 10 parts of fructus amomi; the blood circulation promoting and collateral dredging component comprises the following components: 2 to 5 parts of tree peony bark, 2 to 5 parts of peach seed and 2 to 5 parts of safflower; the yang warming and cold dispelling components comprise the following components: 3 to 7 parts of achyranthes and 2 to 5 parts of cinnamon; the blood replenishing and activating components comprise the following components: 5 to 10 portions of salvia miltiorrhiza, 3 to 7 portions of pseudo-ginseng, 1 to 5 portions of liquorice and 2 to 5 portions of angelica; the spleen and stomach tonifying component also comprises at least one of 5 to 25 parts of glutinous rice and 5 to 15 parts of peanuts. In one embodiment, in the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy, the blood circulation promoting and collateral dredging component further comprises the following components in parts by mass: at least one of 2 to 5 parts of corydalis tuber, 1 to 5 parts of szechuan lovage rhizome and 1 to 3 parts of sappan wood. In one embodiment, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy further comprises the following components in parts by weight: at least one of 5 to 25 parts of glutinous rice and 5 to 15 parts of peanuts; and at least one of 2 to 5 parts of corydalis tuber, 1 to 5 parts of ligusticum wallichii and 1 to 3 parts of sappan wood. In one embodiment, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy further comprises the following components in parts by weight: 5 to 25 parts of glutinous rice or 5 to 15 parts of peanuts; the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy also comprises the following components in parts by weight: 5 to 25 parts of glutinous rice and 5 to 15 parts of peanuts; the rest of the embodiments are analogized and are not described in detail.
In one embodiment, the spleen and stomach tonifying component comprises the following components in parts by weight: 5 to 10 portions of white poria and 5 to 10 portions of fructus amomi; in one embodiment, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy or the spleen and stomach tonifying component further comprises the following components in parts by weight: at least one of 10 to 20 parts of Chinese yam, 2 to 5 parts of red date, 1 to 5 parts of hawthorn and 10 to 20 parts of millet; wherein, the yam, the red date, the hawthorn and the millet can be dry powder, can also be extracts, and can also be dry powder extracts; from the viewpoint of cost, dry powder is preferable. In one embodiment, the spleen and stomach tonifying component further comprises the following components in parts by mass: 10 to 20 parts of yam, 2 to 5 parts of red date, 1 to 5 parts of hawthorn or 10 to 20 parts of millet; in one embodiment, the spleen and stomach tonifying component further comprises the following components in parts by weight: 10 to 20 parts of Chinese yam and 10 to 20 parts of millet; in one embodiment, the spleen and stomach tonifying component further comprises the following components in parts by mass: 10 to 20 parts of yam, 2 to 5 parts of red date, 1 to 5 parts of hawthorn and 10 to 20 parts of millet. When the nutritional health food is used as a meal replacement food, the amount of the spleen and stomach tonifying component can be larger than that of the blood enriching and activating component, or 10 to 20 parts of Chinese yam, 2 to 5 parts of red date, 1 to 5 parts of hawthorn or 10 to 20 parts of millet is defined as a component which does not tonify the spleen and stomach but is a satiety component. The health food is prepared from pure traditional Chinese medicine components, does not contain any western medicine components, is safe to human bodies, has no toxic or side effect and adverse reaction, can be used in large quantities for a long time, and can be eaten instead of meals.
In one embodiment, the blood circulation promoting and collateral dredging component comprises the following components: 2 to 5 parts of tree peony bark, 2 to 5 parts of peach seed and 2 to 5 parts of safflower; in one embodiment, the blood circulation promoting and collateral dredging component further comprises the following components in parts by mass: at least one of 2 to 4 parts of red peony root, 2 to 5 parts of frankincense, 3 to 5 parts of myrrh and 3 to 6 parts of clematis root. The components for promoting blood circulation and removing obstruction in channels are indispensable parts in various embodiments of the application.
In one embodiment, the yang warming and cold dispelling component comprises the following components: 3 to 7 parts of achyranthes and 2 to 5 parts of cinnamon; in one embodiment, the yang-warming and cold-dispelling component further comprises the following components in parts by mass: at least one of 1 to 2 parts of shallot, 1 to 10 parts of leek, 1 to 2 parts of ginger, 1 to 2 parts of clove, 1 to 2 parts of pepper, 1 to 2 parts of cinnamon and 1 to 2 parts of fennel; for the food, especially meal replacement food, related to other embodiments, the yang warming and cold dispelling ingredients of the above embodiments can be selected according to taste to be used as flavoring agents.
In one embodiment, the blood enriching and activating component comprises the following components: 5 to 10 portions of salvia miltiorrhiza, 3 to 7 portions of panax notoginseng, 1 to 5 portions of liquorice and 2 to 5 portions of angelica. In one embodiment, the blood enriching and activating component further comprises the following components in parts by weight: at least one of donkey-hide gelatin 1 to 3 parts, black bean 5 to 10 parts, longan 3 to 7 parts and pumpkin 5 to 10 parts. In one embodiment, the spleen and stomach tonifying component further comprises the following components in parts by weight: at least one of 10 to 20 parts of Chinese yam, 2 to 5 parts of red date, 1 to 5 parts of hawthorn and 10 to 20 parts of millet; and/or the blood circulation promoting and collateral dredging component further comprises the following components in parts by weight: at least one of 2 to 4 parts of red peony root, 2 to 5 parts of frankincense, 3 to 5 parts of myrrh and 3 to 6 parts of clematis root; and/or the yang warming and cold dispelling components further comprise the following components in parts by weight: at least one of 1 to 2 parts of scallion, 1 to 10 parts of leek, 1 to 2 parts of ginger, 1 to 2 parts of clove, 1 to 2 parts of pepper, 1 to 2 parts of cinnamon and 1 to 2 parts of fennel; and/or the blood enriching and activating component also comprises the following components in parts by weight: at least one of donkey-hide gelatin 1 to 3 parts, black bean 5 to 10 parts, longan 3 to 7 parts and pumpkin 5 to 10 parts.
In one embodiment, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by weight: 10 parts of chinaroot greenbrier rhizome extract or dry powder, 5 parts of fructus amomi extract or dry powder, 2 parts of cortex moutan extract or dry powder, 5 parts of peach kernel extract or dry powder, 2 parts of safflower extract or dry powder, 7 parts of achyranthes bidentata extract or dry powder, 2 parts of cinnamon extract or dry powder, 10 parts of salvia miltiorrhiza extract or dry powder, 3 parts of pseudo-ginseng extract or dry powder, 5 parts of liquorice extract or dry powder and 2 parts of angelica extract or dry powder; in one embodiment, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by weight: 5 parts of chinaroot greenbrier rhizome extract or dry powder, 10 parts of fructus amomi extract or dry powder, 5 parts of cortex moutan extract or dry powder, 2 parts of peach kernel extract or dry powder, 2 parts of safflower extract or dry powder, 3 parts of achyranthes root extract or dry powder, 5 parts of cinnamon extract or dry powder, 5 parts of salvia miltiorrhiza extract or dry powder, 7 parts of pseudo-ginseng extract or dry powder, 1 part of liquorice extract or dry powder and 5 parts of angelica extract or dry powder; in one embodiment, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by weight: 6 parts of chinaroot greenbrier rhizome extract or dry powder, 9 parts of fructus amomi extract or dry powder, 4 parts of cortex moutan extract or dry powder, 3 parts of peach kernel extract or dry powder, 4 parts of safflower extract or dry powder, 4 parts of achyranthes root extract or dry powder, 4 parts of cinnamon extract or dry powder, 6 parts of salvia miltiorrhiza extract or dry powder, 6 parts of pseudo-ginseng extract or dry powder, 2 parts of liquorice extract or dry powder and 4 parts of angelica extract or dry powder; in one embodiment, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by weight: 9 parts of chinaroot greenbrier rhizome extract or dry powder, 6 parts of fructus amomi extract or dry powder, 3 parts of cortex moutan extract or dry powder, 4 parts of peach kernel extract or dry powder, 3 parts of safflower extract or dry powder, 6 parts of achyranthes root extract or dry powder, 3 parts of cinnamon extract or dry powder, 9 parts of salvia miltiorrhiza extract or dry powder, 4 parts of pseudo-ginseng extract or dry powder, 4 parts of liquorice extract or dry powder and 3 parts of angelica extract or dry powder; in one embodiment, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by mass: 8 parts of chinaroot greenbrier rhizome extract or dry powder, 7 parts of fructus amomi extract or dry powder, 4 parts of cortex moutan extract or dry powder, 3 parts of peach kernel extract or dry powder, 3 parts of safflower extract or dry powder, 6 parts of achyranthes root extract or dry powder, 4 parts of cinnamon extract or dry powder, 9 parts of salvia miltiorrhiza extract or dry powder, 5 parts of pseudo-ginseng extract or dry powder, 2 parts of liquorice extract or dry powder and 4 parts of angelica extract or dry powder; in one embodiment, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by weight: 7 parts of chinaroot greenbrier rhizome extract or dry powder, 7 parts of fructus amomi extract or dry powder, 3 parts of tree peony bark extract or dry powder, 3 parts of peach kernel extract or dry powder, 3 parts of safflower extract or dry powder, 5 parts of twotooth achyranthes root extract or dry powder, 3 parts of cinnamon extract or dry powder, 8 parts of salvia miltiorrhiza extract or dry powder, 5 parts of pseudo-ginseng extract or dry powder, 3 parts of liquorice extract or dry powder and 3 parts of angelica extract or dry powder.
In the use aspect, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy can be prepared into decoction, tea, pills, powder or meal replacement food; meal replacement food includes, but is not limited to, bars or sheets such as sheet shapes and the like. In one embodiment, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy can be prepared into a tea preparation for soaking or decocting, can be prepared into a soup package for boiling water for taking or replacing water for quenching thirst for taking, can also be prepared into a capsule for taking, can also be prepared into a honeyed pill or soft food for swallowing, and can be prepared into a part of meal replacement powder for eating in a matching way, namely serving as a part of the meal replacement powder. In each example, if a tea preparation, crystal sugar may be added appropriately to adjust the taste. In one embodiment, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy further comprises the following components in parts by weight: 5 to 20 parts of xylitol. The dosage of xylitol is set according to the requirement of taste.
In order to protect a user, the functions of tonifying spleen and stomach, regulating blood vessels, warming yang and dispelling cold are firstly carried out, and further, in one embodiment, the functions of warming yang and dispelling cold, the functions of promoting blood circulation and removing obstruction in channels, the functions of replenishing blood and promoting blood circulation and the functions of tonifying spleen and stomach are cooked to form a three-layer structure, wherein the functions of warming yang and dispelling cold are in the innermost layer, the functions of promoting blood circulation and removing obstruction in channels and the functions of replenishing blood and promoting blood circulation are in the middle layer, and the functions of tonifying spleen and stomach are in the outermost layer. Further, in one embodiment, the yang warming and cold dispelling components are uniformly mixed and prefabricated into micro particles, the blood circulation promoting and collateral dredging components and the blood enriching and activating components are uniformly mixed and coated on the micro particles to form a first inner surface layer, and the spleen and stomach tonifying components are uniformly mixed and coated on the first inner surface layer to form a second outer surface layer, so that the traditional Chinese medicine composition for treating diabetic peripheral vascular diseases is of a three-layer structure with four components as a whole. In one embodiment, the micro-particles are in a strip shape, in one embodiment, the micro-particles are in a rice granule shape or a cylinder shape with two partially spherical ends, in one embodiment, the whole size of the traditional Chinese medicine composition for treating diabetic peripheral vascular diseases is in a rice granule shape, and in one embodiment, the traditional Chinese medicine composition for treating diabetic peripheral vascular diseases is in a three-layer structure, wherein the length of the traditional Chinese medicine composition is less than or equal to 0.3 cm, the width of the traditional Chinese medicine composition is less than or equal to 0.3 cm, and the height of the traditional Chinese medicine composition is less than or equal to 0.9 cm. In one embodiment, yam mucilage can be used or added to enhance the bonding effect when forming the second outer surface layer; in one embodiment, the first inner surface layer and/or the second outer surface layer may be formed by adding or adding wafer pulp to promote adhesion. The design is different from the traditional Chinese medicine decoction or pill, overcomes the defect of complete mixing bias in the traditional industry, is beneficial to forming a three-layer digestion and absorption system on one hand, and firstly tonifies the spleen and stomach, then enriches the blood, activates the blood, promotes the blood circulation, dredges the collaterals, warms the yang and dispels the cold, and finally forms the mixing action; on the other hand, the sugar-bean instant powder is beneficial to the taking and absorption of users, is edible at any time like sugar beans, is easy to control the weight, and is easy to be accepted by the users.
In one embodiment, the preparation method of the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy adopts the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy, and the traditional Chinese medicine composition is uniformly mixed, steamed and prepared into soft food. Since users who need to improve the elasticity of blood vessels are usually older, the soft food meets the eating requirements and is easy to eat. Further, in one embodiment, the components of the traditional Chinese medicine composition for treating diabetic peripheral vascular disease are dry powder. Further, in one embodiment, the soft food is a soft cake or soft pellet with a moisture content of 15% to 60%. In one embodiment, the soft food has a moisture content of 20% to 50%. In one embodiment, the soft food has a moisture content of 20% to 40%. In one embodiment, the soft serve food has a moisture content of 25% to 30%. It is understood that mechanical blending can be used for blending; for example, the components can be dry powder by mechanically mixing and then adding water to steam. The traditional Chinese medicine composition preparation for treating diabetic peripheral vasculopathy contains pure traditional Chinese medicine extract components, does not contain any western medicine components, is prepared from all the medicines which are safe and available to human bodies, has no toxic or side effect and adverse reaction, can be used in large quantities for a long time, can be eaten with meals or meal replacement, and has a good elasticity improvement effect on blood vessels.
In order to facilitate the replacement of a large amount of food, the following points are considered for preparing soft food: the time for taking the food is long, the taking mode is chewing taking, swallowing, water flushing or water delivery, the one-time taking amount is large, and the like. Further, in one embodiment, forming a soft serve food product comprises: placing the mixture into a prefabricated mould, and carrying out extrusion forming. The food can be made into soft food similar to hawthorn strips or hawthorn cakes; because of the extrusion molding, some floating water can be squeezed out. In one embodiment, the extrusion molding further comprises: air drying or baking. In one embodiment, after the extrusion molding and before the airing or baking, the method further comprises: uniformly spreading sesame powder or sesame seeds, wherein the fried sesame powder or sesame seeds are used for air drying, and the raw sesame powder or sesame seeds are used for baking; in one embodiment, the prefabricated mold is in a strip shape, and comprises a cuboid, a cylinder and the like, and a filling body is left in the middle and is used for realizing a structure with a hollow middle after extrusion molding, such as a hollow groove or a hollow space; the soft food is used for making the soft food be virtual but not solid, soft but not floating, and look big but eat little, which is to avoid the excessive consumption of the users with big age; and the structure with the hollow middle is also beneficial to realizing the hollow in the steps of airing or baking, is particularly suitable for placing soft food in a slightly dry state, and is convenient for long people to eat. In one embodiment, the extrusion molding further comprises: a proper amount of air is injected into the soft food in a matrix pin arrangement mode to form a cavity with a preset volume, the preset volume is less than or equal to 3 cubic millimeters, and the matrix pins are injection needles arranged in a matrix and used for injecting air. It can be understood that after steaming, the soft food has a large amount of moisture in the soft food, and due to high viscosity, the components are uniformly mixed and adhered together, so that the soft food is easy to adhere to teeth; therefore, the extrusion forming is meaningful and necessary, and the technical difficulty to be solved is that the material is soft and needs not to collapse into a lump; and the air is injected to form a cavity with a preset volume, so that the air is favorable for matching with the steps of airing or baking, properly controlling the moisture in the soft food, and simultaneously forming a physical ordered vacancy instead of a chemical disordered vacancy, thereby accurately controlling the consistency of a finished product, easily controlling the total dose, being convenient for long-term eating of a long person, avoiding tooth sticking, being easy to digest and being favorable for improving the convenience of eating. In order to facilitate the long-term eating instead of meal, the following points are also considered for preparing the soft food: balanced nutrition, rich taste, various styles and the like.
Further, in one embodiment, after the mixing, powdery seasonings are added to the second outer surface layer, wherein the seasonings comprise salt and sugar, and can also comprise pepper, pepper and/or other seasonings and the like; according to the design, after the food is steamed and made into soft food, different tastes can be reflected at different positions of the same food, the secretion of digestive juice is easy to promote, and the use amount of seasonings is different according to different people classifications, for example, a plurality of chilli powder can be put in the Hunan market, and a plurality of paprika powder can be put in the Sichuan market. Further, in one embodiment, after the mixing, meat is added to the first inner surface layer, the meat includes dried meat slices, meat particles or dried meat floss, and the meat is classified according to different people groups, for example, dried meat slices with good teeth can be used, and dried meat floss with bad teeth can be used; this embodiment requires a suitable increase in the volume of the three-layer structure, i.e. it is slightly larger. Protein powder or milk powder can also be added properly. Further, in one embodiment, before steaming or in extrusion molding, the method further comprises: injecting a proper amount of pre-fermented dough into the soft food in a matrix pin arrangement mode to form an expansion part with a preset volume, wherein the preset volume is less than or equal to 3 cubic millimeters, namely the volume of the expanded dough is less than or equal to 3 cubic millimeters. In one embodiment, the extrusion molding further comprises: and (6) baking. The design is beneficial to providing meal replacement food with rich taste, various styles and balanced nutrition, and is suitable for long-term eating.
Further, in one embodiment, the steaming is realized by using a pre-made steamer, one surface of the pre-made steamer, which is far away from the steam direction, is provided with the matrix pins facing the steamed Chinese medicinal composition preparation, such as soft food which is not steamed yet, and air is injected downwards through the matrix pins to form a certain empty space, wherein the volume of the empty space is less than or equal to 3 cubic millimeters. In one embodiment, during steaming, air is injected during an initial stage to maintain the interior and outlet of the matrix pins from clogging, and during an intermediate stage to create a void, e.g., about half of the time.
Taking the components as dry powder as an example, the actual effect of the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy is shown by comparison.
Example 1: as shown in fig. 4, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by weight: 10 parts of white poria cocos dry powder, 5 parts of fructus amomi dry powder, 2 parts of moutan bark dry powder, 5 parts of peach kernel dry powder, 2 parts of safflower dry powder, 7 parts of achyranthes bidentata dry powder, 2 parts of cinnamon dry powder, 10 parts of salvia miltiorrhiza dry powder, 3 parts of panax notoginseng dry powder, 5 parts of liquorice dry powder and 2 parts of angelica sinensis dry powder; wherein, 1 part is 0.34 g, and 1 agent is 18.02 g in total; three doses are taken every day in a meal.
Example 2: as shown in fig. 5, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by weight: 5 parts of white poria cocos dry powder, 10 parts of fructus amomi dry powder, 5 parts of moutan bark dry powder, 2 parts of peach kernel dry powder, 2 parts of safflower dry powder, 3 parts of achyranthes root dry powder, 5 parts of cinnamon dry powder, 5 parts of salvia miltiorrhiza dry powder, 7 parts of pseudo-ginseng dry powder, 1 part of liquorice dry powder and 5 parts of angelica sinensis dry powder; wherein, 1 part is 0.36 g, and 1 agent is 18 g in total; three doses are taken every day in a meal.
Example 3: as shown in fig. 6, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by weight: 6 parts of poria cocos dry powder, 9 parts of fructus amomi dry powder, 4 parts of moutan bark dry powder, 3 parts of peach kernel dry powder, 4 parts of safflower dry powder, 4 parts of achyranthes bidentata dry powder, 4 parts of cinnamon dry powder, 6 parts of salvia miltiorrhiza dry powder, 6 parts of panax notoginseng dry powder, 2 parts of liquorice dry powder and 4 parts of angelica sinensis dry powder; wherein, 1 part is 0.345 g, and 1 dose is 17.94 g in total; three doses are taken every day in a meal.
Example 4: as shown in fig. 7, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by weight: 9 parts of poria cocos dry powder, 6 parts of fructus amomi dry powder, 3 parts of moutan bark dry powder, 4 parts of peach kernel dry powder, 3 parts of safflower dry powder, 6 parts of achyranthes bidentata dry powder, 3 parts of cinnamon dry powder, 9 parts of salvia miltiorrhiza dry powder, 4 parts of panax notoginseng dry powder, 4 parts of liquorice dry powder and 3 parts of angelica sinensis dry powder; wherein, 1 part is 0.335 g, and 1 dose is 18.09 g in total; three doses are taken every day in a meal.
Example 5: as shown in fig. 8, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by weight: 8 parts of poria cocos dry powder, 7 parts of fructus amomi dry powder, 4 parts of moutan bark dry powder, 3 parts of peach kernel dry powder, 3 parts of safflower dry powder, 6 parts of achyranthes bidentata dry powder, 4 parts of cinnamon dry powder, 9 parts of salvia miltiorrhiza dry powder, 5 parts of pseudo-ginseng dry powder, 2 parts of liquorice dry powder and 4 parts of angelica sinensis dry powder; wherein, 1 part is 0.328 g, and 1 agent is 18.04 g in total; three doses are taken every day in a meal.
Example 6: as shown in fig. 9, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy comprises the following components in parts by weight: 7 parts of white poria cocos dry powder, 7 parts of fructus amomi dry powder, 3 parts of moutan bark dry powder, 3 parts of peach kernel dry powder, 3 parts of safflower dry powder, 5 parts of achyranthes bidentata dry powder, 3 parts of cinnamon dry powder, 8 parts of salvia miltiorrhiza dry powder, 5 parts of pseudo-ginseng dry powder, 3 parts of liquorice dry powder and 3 parts of angelica sinensis dry powder. Wherein, 1 part is 0.36 g, and 1 dose is 18 g in total; three doses are taken every day in a meal.
The concrete is shown in the following table 1:
TABLE 1
Example 7: based on the embodiment 5 and different from the embodiment 5, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy further comprises 25 parts of glutinous rice, 12 parts of peanuts, 4 parts of corydalis tuber, 2 parts of ligusticum wallichii and 1 part of sappan wood by mass. 1 dose amounted to 32.472 grams. In this embodiment, 37 parts of the spleen and stomach tonifying component are added, and 7 parts of the blood circulation promoting and collateral dredging component are added.
Example 8: based on example 5 and different from example 5, the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy further comprises 23 parts of glutinous rice, 15 parts of peanuts, 18 parts of Chinese yams, 4 parts of red dates, 3 parts of hawthorns, 15 parts of millets, 6 parts of leeks and 10 parts of pumpkins by mass. Total 48.872 g of 1 dose. The yang warming and cold dispelling components are uniformly mixed to be prefabricated into micro particles, the blood circulation promoting and collateral dredging components and the blood enriching and activating components are uniformly mixed and coated on the micro particles to form a first inner surface layer, the spleen and stomach tonifying components are uniformly mixed and coated on the first inner surface layer to form a second outer surface layer, so that the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy integrally has a three-layer structure of four components, the length of the traditional Chinese medicine composition is about 0.28 +/-0.02 cm, the width of the traditional Chinese medicine composition is about 0.28 +/-0.02 cm, and the height of the traditional Chinese medicine composition is about 0.8 +/-0.05 cm; it is clear that many granular three-layer structures are possible. In the embodiment, 78 parts of components for tonifying spleen and stomach are increased, 6 parts of components for warming yang and dispelling cold are increased, and 10 parts of components for enriching and activating blood are increased.
Comparative example 1: 18 g of corn dry powder; three doses are taken every day with meals.
Comparative example 2: 18 g of dry rice powder; three doses are taken every day with meals.
In 10 groups, 5 volunteers were matched for each group, the age was not less than 50 years old and not more than 70 years old, diabetes was diagnosed for more than 5 years, and peripheral vascular disease symptoms were observed. The peripheral vascular disease symptoms are subjective symptoms such as limb pain, numbness, fever or cold, soreness, swelling, weakness and the like; intermittent claudication, resting pain; the finger tip skin temperature is reduced, the hair is shed and other nutritional disorder changes, the lower limb arterial pulsation is weakened or disappeared, the arterial systolic pressure is reduced, and the limb ulcer, gangrene and the like are caused. The following tests were performed before the test was started:
resting Ankle/Brachial Index (ABI) measurements are performed by measuring the systolic pressure of the posterior or anterior tibial artery of the Ankle and the Brachial artery to obtain the ratio of the pressure of the Ankle artery to the pressure of the Brachial artery.
And (3) an imaging examination, namely examining whether the endarterium plaque of the limb artery is formed, narrowed or occluded by respectively adopting color Doppler ultrasound and CT (computed tomography) angiography.
Serum C-reactive protein (CRP) assay. The C-reactive protein is a phase protein generated in human body emergency, and the concentration of the C-reactive protein in the serum of healthy human is very low, usually lower than 1mg/L, and generally not more than 10mg/L. It rises rapidly in the presence of inflammation.
The traditional Chinese medicine curative effect standard is as follows: pain, numbness and burning sensation of limbs are measured according to the conventional scoring standard of 0-10.
The details before the start of the test are shown in table 2 below:
TABLE 2
In Table 2, the unit of CRP is mg/L, and the mean value is taken according to the standard of traditional Chinese medicine curative effect.
The results of the tests performed on days 60 and 90 are shown in Table 3 below:
TABLE 3
Table 3 identification for plaques: the increase in the area occupied by the plaque by 1% to 5% is indicated as +1, the decrease in the area occupied by the plaque by 1% to 5% (including 5%) is indicated as-1, the decrease in the area occupied by the plaque by 5% (excluding 5%) to 10% (including 10%) is indicated as-2, the decrease in the area occupied by the plaque by 10% (excluding 10%) to 15% (including 15%) is indicated as-3, the decrease in the area occupied by the plaque by 15% (excluding 15%) to 20% (including 20%) is indicated as-4, and so on.
As can be seen from comparison of tables 2 and 3, comparative examples 1 and 2 showed substantially no improvement effect, and it was confirmed that it was difficult for volunteers to improve diabetic peripheral vascular disease by self-regulation and placebo, and there was a high possibility of continuous deterioration due to life style and the like.
The ABI indexes in examples 1 to 8 are obviously increased, the ABI index on the 90 th day is superior to the ABI index on the 60 th day, and the ABI index on the 60 th day is superior to the ABI index before the test, namely, examples 1 to 8 have obvious, positive and sustainable improvement effects on the ABI indexes, namely, the ABI indexes are favorably improved after being eaten for a long time, and the improvement of the ABI indexes can show the improvement of the peripheral artery disease of the lower limbs.
In examples 1 to 8, the plaque was found to be significantly improved on day 90 by imaging examination. The occupied areas of the plaques are reduced to different degrees, and the fact that the plaque condition can be improved by eating the traditional Chinese medicine composition for treating diabetic peripheral vascular lesions for a long time is proved, namely, the phenomenon that the intima of the limb arteries is narrowed or blocked due to lesions is avoided.
The CRP index is significantly reduced in examples 1 to 8, and the CRP index at the 90 th day is better than the CRP index at the 60 th day, and the CRP index at the 60 th day is better than the CRP index before the test starts, i.e., examples 1 to 8 have obvious, positive and sustainable improvement effect on the CRP index, i.e., the CRP index is favorably improved after long-term consumption, and the improvement of the CRP index can show the improvement of inflammation.
According to the traditional Chinese medicine curative effect standard including the conventional scores of limb pain, numbness and burning sensation, the examples 1 to 8 have obvious improvement effects, and the examples 1 to 8 are proved to have certain effects on improving the limb pain, the numbness and the burning sensation; and the standards of the traditional Chinese medicine curative effect on the 90 th day are relatively superior to those of the traditional Chinese medicine curative effect on the 60 th day, and the standards of the traditional Chinese medicine curative effect on the 60 th day are relatively superior to those of the traditional Chinese medicine curative effect before the test is started, so that the results prove that the examples 1 to 8 have certain, positive and sustainable improvement effects on improving pain of patients and improving the quality of life.
Therefore, the embodiments 1 to 8 have a certain effect on treating diabetic peripheral vasculopathy, and the effect of the embodiment 8 is the best, and the embodiments 5, 6 and 7 are slightly less, which proves that the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy has a better effect on treating diabetic peripheral vasculopathy due to the effective mixture ratio of the components for tonifying spleen and stomach, the components for promoting blood circulation and removing obstruction in channels, the components for warming yang and dispelling cold and the components for replenishing blood and promoting blood circulation.
In addition, it was found in the long-term follow-up test that examples 1 to 8 all had significant effects on the recovery of diabetic peripheral vasculopathy by long-term eating for more than 3 months. In addition, the applicant also made a lot of tests, not limited to examples 1 to 8, and the test results all show that the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy or the preparation thereof has a positive effect on improving the diabetic peripheral vasculopathy on the premise of long-term consumption for more than a certain time and a certain dosage, and the traditional Chinese medicine composition or the preparation thereof should be paid attention and protected because no western medicine component is added.
In addition, the traditional Chinese medicine composition preparation for treating diabetic peripheral vascular diseases is prepared into soft food by adopting the preparation method of the traditional Chinese medicine composition for treating diabetic peripheral vascular diseases, the applicant prepares two products, one product is in a block shape similar to a biscuit or a steamed bread, and the package is similar to a biscuit; the other is paste with better fluidity, which is similar to toothpaste, and the package is also similar to toothpaste; the block is easy to be recognized after being used for a long time by selecting volunteers. The long-term use of the traditional Chinese medicine composition not only can not find side effects and adverse reactions, but also has better recovery effect on diabetic peripheral vascular diseases, namely has the effect of improving the diabetic peripheral vascular diseases, is worthy of further intensive research, and theoretically has better sales expectation.
Furthermore, from the analysis of compatibility mechanism, the diabetic peripheral vascular disease belongs to the category of 'arthralgia syndrome' in traditional Chinese medicine, mainly shows cold pain of lower limbs and intermittent claudication, and has the effects of promoting blood circulation to remove blood stasis, enriching and activating blood on the basis of controlling blood sugar, and is matched with the effects of tonifying spleen and stomach, warming yang and dispelling cold to ensure that the blood can smoothly flow. The embodiments of the application have the effects of tonifying spleen and stomach, promoting blood circulation to remove meridian obstruction, warming yang to dispel cold and enriching blood and promoting blood circulation, and can be used for assisting generation and matching generation, and the compatible components are long-term use and verified to have no toxic or side effect, proper component control, safety and reliability, and are suitable for long-term edible treatment of chronic diseases.
Other embodiments of the present application further include a traditional Chinese medicine composition for treating diabetic peripheral vascular disease, which is formed by combining technical features of the above embodiments, and a preparation method thereof. The weight-reducing health-care food has the advantages of no toxic or side effect, no addition of western medicine components, high safety performance, and suitability for long-term large-scale use, wherein some embodiments can be used as a substitute for meals, and the weight-reducing health-care food has a weight-reducing effect to a certain extent by being matched with the supplement of starch and cellulose, and helps patients to overcome 'rich and noble diseases' caused by 'rich and noble life', namely diabetes.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only express several embodiments of the present application, and the description thereof is more specific and detailed, but not construed as limiting the claims. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the concept of the present application, which falls within the scope of protection of the present application. Therefore, the protection scope of the present application shall be subject to the appended claims.
Claims (10)
1. A traditional Chinese medicine composition for treating diabetic peripheral vasculopathy is characterized by only comprising the following components: spleen and stomach tonifying components, blood circulation promoting and collateral dredging components, yang warming and cold dispelling components, and blood replenishing and blood circulation promoting components; according to the mass portion of the raw materials,
the spleen and stomach tonifying components only comprise the following components: 5 to 10 parts of white poria and 5 to 10 parts of fructus amomi;
the blood circulation promoting and collateral dredging component only comprises the following components: 2 to 5 parts of tree peony bark, 2 to 5 parts of peach seed and 2 to 5 parts of safflower;
the yang warming and cold dispelling component only comprises the following components: 3 to 7 parts of achyranthes and 2 to 5 parts of cinnamon;
the blood enriching and activating components only comprise the following components: 5 to 10 portions of salvia miltiorrhiza, 3 to 7 portions of panax notoginseng, 1 to 5 portions of liquorice and 2 to 5 portions of angelica;
the dosage of the blood replenishing and activating component is larger than that of the spleen and stomach tonifying component, and the dosage of the spleen and stomach tonifying component is larger than that of the blood activating and collaterals dredging component and that of the yang warming and cold dispelling component.
2. The traditional Chinese medicine composition for treating diabetic peripheral vasculopathy according to claim 1, which is characterized by comprising the following components in parts by mass:
5 to 10 parts of chinaroot greenbrier rhizome extract, 5 to 10 parts of fructus amomi extract, 2 to 5 parts of moutan bark extract, 2 to 5 parts of peach kernel extract, 2 to 5 parts of safflower extract, 3 to 7 parts of achyranthes root extract, 2 to 5 parts of cinnamon extract, 5 to 10 parts of salvia miltiorrhiza extract, 3 to 7 parts of pseudo-ginseng extract, 1 to 5 parts of liquorice extract and 2 to 5 parts of angelica extract; or,
5 to 10 parts of white poria dry powder, 5 to 10 parts of fructus amomi dry powder, 2 to 5 parts of cortex moutan dry powder, 2 to 5 parts of peach kernel dry powder, 2 to 5 parts of safflower dry powder, 3 to 7 parts of achyranthes root dry powder, 2 to 5 parts of cinnamon dry powder, 5 to 10 parts of salvia miltiorrhiza dry powder, 3 to 7 parts of pseudo-ginseng dry powder, 1 to 5 parts of liquorice dry powder and 2 to 5 parts of angelica sinensis dry powder.
3. The traditional Chinese medicine composition for treating diabetic peripheral vasculopathy according to claim 2, which is characterized by comprising the following components in parts by weight:
6 to 9 parts of chinaroot greenbrier rhizome extract or dry powder, 6 to 9 parts of villous amomum fruit extract or dry powder, 3 to 4 parts of tree peony bark extract or dry powder, 3 to 4 parts of peach kernel extract or dry powder, 3 to 4 parts of safflower extract or dry powder, 4 to 6 parts of twotooth achyranthes root extract or dry powder, 3 to 4 parts of cassia bark extract or dry powder, 6 to 9 parts of red sage root extract or dry powder, 4 to 6 parts of pseudo-ginseng extract or dry powder, 2 to 4 parts of licorice root extract or dry powder and 3 to 4 parts of Chinese angelica extract or dry powder.
4. The traditional Chinese medicine composition for treating diabetic peripheral vasculopathy according to claim 2, which is characterized by comprising the following components in parts by weight:
10 parts of chinaroot greenbrier rhizome extract or dry powder, 5 parts of fructus amomi extract or dry powder, 2 parts of cortex moutan extract or dry powder, 5 parts of peach kernel extract or dry powder, 2 parts of safflower extract or dry powder, 7 parts of achyranthes bidentata extract or dry powder, 2 parts of cinnamon extract or dry powder, 10 parts of salvia miltiorrhiza extract or dry powder, 3 parts of pseudo-ginseng extract or dry powder, 5 parts of liquorice extract or dry powder and 2 parts of angelica extract or dry powder; or,
5 parts of chinaroot greenbrier rhizome extract or dry powder, 10 parts of fructus amomi extract or dry powder, 5 parts of cortex moutan extract or dry powder, 2 parts of peach kernel extract or dry powder, 2 parts of safflower extract or dry powder, 3 parts of achyranthes root extract or dry powder, 5 parts of cinnamon extract or dry powder, 5 parts of salvia miltiorrhiza extract or dry powder, 7 parts of pseudo-ginseng extract or dry powder, 1 part of liquorice extract or dry powder and 5 parts of angelica extract or dry powder; or,
6 parts of chinaroot greenbrier rhizome extract or dry powder, 9 parts of fructus amomi extract or dry powder, 4 parts of cortex moutan extract or dry powder, 3 parts of peach kernel extract or dry powder, 4 parts of safflower extract or dry powder, 4 parts of achyranthes root extract or dry powder, 4 parts of cinnamon extract or dry powder, 6 parts of salvia miltiorrhiza extract or dry powder, 6 parts of pseudo-ginseng extract or dry powder, 2 parts of liquorice extract or dry powder and 4 parts of angelica extract or dry powder; or,
9 parts of chinaroot greenbrier rhizome extract or dry powder, 6 parts of fructus amomi extract or dry powder, 3 parts of cortex moutan extract or dry powder, 4 parts of peach kernel extract or dry powder, 3 parts of safflower extract or dry powder, 6 parts of achyranthes root extract or dry powder, 3 parts of cinnamon extract or dry powder, 9 parts of salvia miltiorrhiza extract or dry powder, 4 parts of pseudo-ginseng extract or dry powder, 4 parts of liquorice extract or dry powder and 3 parts of angelica extract or dry powder; or,
8 parts of chinaroot greenbrier rhizome extract or dry powder, 7 parts of fructus amomi extract or dry powder, 4 parts of cortex moutan extract or dry powder, 3 parts of peach kernel extract or dry powder, 3 parts of safflower extract or dry powder, 6 parts of achyranthes root extract or dry powder, 4 parts of cinnamon extract or dry powder, 9 parts of salvia miltiorrhiza extract or dry powder, 5 parts of pseudo-ginseng extract or dry powder, 2 parts of liquorice extract or dry powder and 4 parts of angelica extract or dry powder; or,
7 parts of chinaroot greenbrier rhizome extract or dry powder, 7 parts of fructus amomi extract or dry powder, 3 parts of cortex moutan extract or dry powder, 3 parts of peach kernel extract or dry powder, 3 parts of safflower extract or dry powder, 5 parts of achyranthes root extract or dry powder, 3 parts of cinnamon extract or dry powder, 8 parts of salvia miltiorrhiza extract or dry powder, 5 parts of pseudo-ginseng extract or dry powder, 3 parts of liquorice extract or dry powder and 3 parts of angelica extract or dry powder.
5. The traditional Chinese medicine composition for treating diabetic peripheral vasculopathy according to claim 1, wherein the components for tonifying spleen and stomach, promoting blood circulation and removing obstruction in channels, warming yang and dispelling cold and the components for enriching and promoting blood circulation are in a ratio of A to B to C to D in parts by mass;
wherein A is 4 to 8, B is 3 to 5, C is 3 to 5, and D is 6 to 10.
6. The Chinese medicinal composition for treating diabetic peripheral vasculopathy according to claim 5, wherein A is 6, B is 4, C is 4, and D is 8.
7. The traditional Chinese medicine composition for treating diabetic peripheral vasculopathy according to claim 5, wherein the white poria cocos is the same as the fructus amomi, the moutan bark and the peach kernel are the same as the safflower, the ratio of the achyranthes bidentata to the cinnamon is 2.
8. The traditional Chinese medicine composition for treating diabetic peripheral vasculopathy according to claim 7, wherein the ratio of red sage root, pseudo-ginseng, angelica sinensis and licorice root is 4.
9. The traditional Chinese medicine composition for treating diabetic peripheral vasculopathy according to any claim 1 to 8, wherein the components are all extracts or all dry powders.
10. A preparation method of a traditional Chinese medicine composition for treating diabetic peripheral vasculopathy, which is characterized by adopting the traditional Chinese medicine composition for treating diabetic peripheral vasculopathy according to any one of claims 1 to 9, uniformly mixing, steaming and packaging.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202110830240.4A CN113350467B (en) | 2021-07-22 | 2021-07-22 | Traditional Chinese medicine composition for treating diabetic peripheral vasculopathy and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202110830240.4A CN113350467B (en) | 2021-07-22 | 2021-07-22 | Traditional Chinese medicine composition for treating diabetic peripheral vasculopathy and preparation method thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN113350467A CN113350467A (en) | 2021-09-07 |
CN113350467B true CN113350467B (en) | 2023-03-28 |
Family
ID=77540115
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202110830240.4A Active CN113350467B (en) | 2021-07-22 | 2021-07-22 | Traditional Chinese medicine composition for treating diabetic peripheral vasculopathy and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN113350467B (en) |
-
2021
- 2021-07-22 CN CN202110830240.4A patent/CN113350467B/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN113350467A (en) | 2021-09-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR20050013370A (en) | Fatness remedy composition using Chinese medicine | |
CN103340341A (en) | Functional food with bone strengthening effect and preparation method thereof | |
CN104306655A (en) | Vegetable preparation for reducing blood pressure, blood glucose and blood fat and preparation method thereof | |
CN104940531A (en) | Application of Chinese herbal composition to preparation of medicine for treating diabetic nephropathy | |
CN103960429A (en) | Health food with effect of healthily reducing weight of user | |
CN113350467B (en) | Traditional Chinese medicine composition for treating diabetic peripheral vasculopathy and preparation method thereof | |
CN103432391A (en) | Medicament for treating hyperlipemia and preparation method thereof | |
CN109718353A (en) | The traditional Chinese medicine pill and preparation method thereof for treating constipation | |
CN105056103A (en) | Steamed buns with assistant effect of reducing blood fat and cholesterol and processing method of steamed buns | |
CN109602817A (en) | A kind for the treatment of is reduced the Chinese medicine composition of caused osteoporosis by estrogen | |
CN104825821A (en) | Medicine for treating diabetes and preparation method thereof | |
CN109999058A (en) | A kind of molten method of glue class Chinese medicine and product, and the solid beverage as made from the product and preparation method thereof | |
CN105213808A (en) | A kind of hemopoietic cream of nourishing face and preparation method thereof | |
CN108552383A (en) | A kind of corn stigma dandelion herb tea and preparation method thereof | |
CN102512642B (en) | Medicinal composition for treating spleen and stomach diseases and application thereof | |
CN113144023A (en) | Traditional Chinese medicine composition and preparation for improving vascular elasticity and preparation method thereof | |
CN110101818A (en) | A kind of Chinese medicine for treating diabetes | |
CN105796755A (en) | Traditional Chinese medicinal composition for treating diabetic nephropathy | |
CN108671055A (en) | A kind of Chinese medicine composition of spleen tonifying and fat and preparation method thereof | |
CN113016969A (en) | Yin deficiency constitution health-care solid beverage and preparation method thereof | |
CN103892006A (en) | Brain tonic anti-aging tea | |
CN108142930A (en) | For improving the Chinese herbal ointment formula of damp-heat constitution and its processing method | |
CN108938747A (en) | It is a kind of increase bone density composition and its application | |
CN108785589A (en) | Application of the intelligence development invigorating spleen prescription composition in preparing food | |
CN108703304A (en) | Return glue instant health-maintenance porridge powder and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant |