CN113350222A - Toothpaste and preparation method thereof - Google Patents

Toothpaste and preparation method thereof Download PDF

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Publication number
CN113350222A
CN113350222A CN202110808141.6A CN202110808141A CN113350222A CN 113350222 A CN113350222 A CN 113350222A CN 202110808141 A CN202110808141 A CN 202110808141A CN 113350222 A CN113350222 A CN 113350222A
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China
Prior art keywords
percent
sodium
toothpaste
polyethylene glycol
ethanol
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Pending
Application number
CN202110808141.6A
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Chinese (zh)
Inventor
邓家能
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Individual
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Individual
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Priority to CN202110808141.6A priority Critical patent/CN113350222A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25Silicon; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/737Galactomannans, e.g. guar; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses toothpaste, which comprises the following raw materials: the toothpaste comprises polyethylene glycol, dihydroxypropane, carrageenan, xanthan gum, ethanol, trehalose, saccharin sodium, acesulfame potassium, silicon dioxide, sodium bicarbonate, sodium tetrapolyphosphate, poloxamer, potassium hydroxide, sodium pyrophosphate, sodium lauryl sulfate and essence, and is characterized in that the toothpaste is improved in stability by adding medicinal thermal-sensitive material components, so that the problem of oral health caused by cold water stimulation to teeth in the morning can be effectively solved, and meanwhile, medicinal factors can be added, so that the medicinal effect of the toothpaste can be improved by 75%; after the thermal inductance toothpaste provided by the invention is used, the breath is fresh and pleasant, and the oral cleaning effect is good.

Description

Toothpaste and preparation method thereof
Technical Field
The invention belongs to the technical field of toothpaste, and particularly relates to toothpaste and a preparation method thereof.
Background
Because people are in a nervous life rhythm, when the oral cavity has slight problems or slight pain, the people cannot consult or seek medical advice in time, at the moment, good oral hygiene habits are kept, the toothpaste is used as a daily article frequently used in life of people and is the first lowest cost effective barrier for preventing and protecting the oral health, and the health-care toothpaste is different from the common toothpaste by adding a certain specific active ingredient into the toothpaste, so the health-care toothpaste is more and more concerned and loved by people.
At present, a toothpaste is newly developed, when the heat-sensitive toothpaste is used for brushing teeth, the toothpaste can generate heat, the teeth can feel hot, stubborn tooth stains can be dissolved and then removed, but in the prior art, the heat-sensitive toothpaste has unsafe factors that the teeth can be scalded due to improper use, and on the other hand, the removal rate and the stability are not good.
Therefore, the technical personnel in the field need to solve the problem of providing safer and more stable thermal toothpaste and a preparation method thereof.
Disclosure of Invention
In view of the above, the invention provides toothpaste and a preparation method thereof, and the toothpaste has the advantages that the stability is improved by adding the medicinal thermal material component, so that the problem of oral health caused by cold water stimulation to teeth during cleaning of the teeth in the morning can be effectively relieved, and meanwhile, the medicinal factor can be added, so that the medicinal effect of the toothpaste can be improved by 75%; after the thermal inductance toothpaste provided by the invention is used, the breath is fresh and pleasant, and the oral cleaning effect is good.
In order to achieve the purpose, the invention adopts the following technical scheme:
a toothpaste, comprising the raw materials: polyethylene glycol, dihydroxypropane, carrageenan, xanthan gum, ethanol, trehalose, saccharin sodium, acesulfame potassium, silicon dioxide, sodium bicarbonate, sodium tetrapolyphosphate, poloxamer, potassium hydroxide, sodium pyrophosphate, sodium lauryl sulfate and essence.
Preferably, the polyethylene glycol, the ethanol, the silicon dioxide and the carrageenan are all medical grade.
Preferably, the method comprises the following raw materials: by mass percent, 34.5 percent of polyethylene glycol, 2 percent of dihydroxypropane, 0.125 percent of carrageenan, 0.35 percent of xanthan gum, 3 percent of ethanol, 0.4 percent of trehalose, 0.15 percent of saccharin sodium, 0.2 percent of acesulfame, 10 percent of silicon dioxide, 4 percent of sodium bicarbonate, 1 percent of tetrapolyphosphate, 1 percent of poloxamer, 0.08 percent of potassium hydroxide, 0.3 percent of sodium pyrophosphate, 1.4 percent of sodium lauryl sulfate and 0.6 percent of essence.
Preferably, the traditional Chinese medicine composition also comprises a traditional Chinese medicine extract or a western medicine extract.
The preparation method of the toothpaste specifically comprises the following steps:
(1) weighing raw materials of polyethylene glycol, ethanol, glycerol, silicon dioxide, propylene glycol, baking soda, xanthan gum, carrageenan, sodium lauryl sulfate, tetrasodium phosphate, sodium hexametaphosphate, poloxamer, a heat booster and trehalose for later use;
(2) mixing the polyethylene glycol, the propylene glycol and the carrageenan uniformly, stirring to be colloidal, then sequentially adding the silicon dioxide, the baking soda, the sodium lauryl sulfate and the edible essence, stirring to be pasty, and vacuumizing to obtain the toothpaste.
Preferably, the rotation speed of the stirring in the step (2) is 160-260 rpm.
Preferably, the stirring time to paste in the step (2) is 20 min.
Preferably, the time for vacuumizing in step (2) is 40 min.
Preferably, the stirring in step (2) is carried out in a vacuum machine.
According to the technical scheme, compared with the prior art, the invention has the following beneficial effects: the invention provides a toothpaste and a preparation method thereof, the toothpaste has improved stability by adding medicinal thermal material components, can effectively relieve the oral health problem caused by cold water stimulating teeth in the morning cleaning of teeth, and can improve the medicinal effect by 75% by adding medicinal factors; after the thermal inductance toothpaste provided by the invention is used, the breath is fresh and pleasant, and the oral cleaning effect is good.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The preparation method of the toothpaste specifically comprises the following steps:
(1) weighing raw materials, by mass, 34.5% of medical polyethylene glycol, 2% of dihydroxypropane, 0.125% of carrageenan, 0.35% of xanthan gum, 3% of medical ethanol, 0.4% of edible trehalose, 0.15% of saccharin sodium, 0.2% of acesulfame potassium, 10% of silicon dioxide, 4% of sodium bicarbonate, 1% of tetrasodium polyphosphate, 1% of poloxamer, 0.08% of potassium hydroxide, 0.3% of sodium pyrophosphate, 1.4% of sodium lauryl sulfate and 0.6% of essence for later use;
(2) mixing polyethylene glycol, propylene glycol and carrageenan uniformly, stirring at 160rpm to colloid, sequentially adding silicon dioxide, sodium bicarbonate, sodium lauryl sulfate and edible essence, stirring at 160rpm for 20min to paste, and vacuumizing for 40min to obtain the toothpaste.
Example 2
The preparation method of the toothpaste specifically comprises the following steps:
(1) weighing raw materials, by mass, 34.5% of medical polyethylene glycol, 2% of dihydroxypropane, 0.125% of carrageenan, 0.35% of xanthan gum, 3% of medical ethanol, 0.4% of edible trehalose, 0.15% of saccharin sodium, 0.2% of acesulfame potassium, 10% of silicon dioxide, 4% of sodium bicarbonate, 1% of tetrasodium polyphosphate, 1% of poloxamer, 0.08% of potassium hydroxide, 0.3% of sodium pyrophosphate, 1.4% of sodium lauryl sulfate and 0.6% of essence for later use;
(2) mixing polyethylene glycol, propylene glycol and carrageenan uniformly, stirring at 260rpm to colloid, sequentially adding silicon dioxide, sodium bicarbonate, sodium lauryl sulfate and edible essence, stirring at 260rpm for 20min to paste, and vacuumizing for 40min to obtain the toothpaste.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (9)

1. A toothpaste, comprising the raw materials: polyethylene glycol, dihydroxypropane, carrageenan, xanthan gum, ethanol, trehalose, saccharin sodium, acesulfame potassium, silicon dioxide, sodium bicarbonate, sodium tetrapolyphosphate, poloxamer, potassium hydroxide, sodium pyrophosphate, sodium lauryl sulfate and essence.
2. A toothpaste as claimed in claim 1, wherein said polyethylene glycol, said ethanol and said silica are all of medical grade.
3. A toothpaste according to claim 1 or 2, comprising the raw materials: by mass percent, 34.5 percent of polyethylene glycol, 2 percent of dihydroxypropane, 0.125 percent of carrageenan, 0.35 percent of xanthan gum, 3 percent of ethanol, 0.4 percent of trehalose, 0.15 percent of saccharin sodium, 0.2 percent of acesulfame, 10 percent of silicon dioxide, 4 percent of sodium bicarbonate, 1 percent of tetrapolyphosphate, 1 percent of poloxamer, 0.08 percent of potassium hydroxide, 0.3 percent of sodium pyrophosphate, 1.4 percent of sodium lauryl sulfate and 0.6 percent of essence.
4. The toothpaste according to claim 3, further comprising a herbal extract or a western medicine extract.
5. The preparation method of the toothpaste is characterized by comprising the following steps:
(1) weighing raw materials of polyethylene glycol, dihydroxypropane, carrageenan, xanthan gum, ethanol, trehalose, saccharin sodium, acesulfame potassium, silicon dioxide, sodium bicarbonate, sodium tetrapolyphosphate, poloxamer, potassium hydroxide, sodium pyrophosphate, sodium lauryl sulfate and essence for later use;
(2) uniformly mixing the polyethylene glycol, the dihydroxypropane, the carrageenan and the xanthan gum, stirring to obtain paste, sequentially adding the mixture of the trehalose, the saccharin sodium and the acesulfame dissolved by the ethanol, uniformly stirring, sequentially adding the silicon dioxide, the sodium bicarbonate, the sodium tetrapolyphosphate, the poloxamer, the potassium hydroxide and the sodium pyrophosphate, stirring to obtain paste, finally adding the sodium lauryl sulfate and the essence, uniformly stirring, and vacuumizing to obtain the toothpaste.
6. The method for preparing toothpaste as claimed in claim 5, wherein the stirring speed in step (2) is 160-260 rpm.
7. The method for preparing toothpaste according to claim 5, wherein the time for stirring to paste in step (2) is 20 min.
8. The method for preparing toothpaste according to claim 5, wherein the time period for vacuuming in step (2) is 40 min.
9. The method of claim 5, wherein the step (2) is carried out in a vacuum.
CN202110808141.6A 2021-07-16 2021-07-16 Toothpaste and preparation method thereof Pending CN113350222A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110808141.6A CN113350222A (en) 2021-07-16 2021-07-16 Toothpaste and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110808141.6A CN113350222A (en) 2021-07-16 2021-07-16 Toothpaste and preparation method thereof

Publications (1)

Publication Number Publication Date
CN113350222A true CN113350222A (en) 2021-09-07

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CN202110808141.6A Pending CN113350222A (en) 2021-07-16 2021-07-16 Toothpaste and preparation method thereof

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101132761A (en) * 2004-12-29 2008-02-27 高露洁-棕榄公司 Oxidation resistant dentifrice compositions
CN110123702A (en) * 2019-06-17 2019-08-16 中山市多美化工有限公司 A kind of toothpaste and preparation method thereof containing hyaluronic acid and trehalose
CN110267641A (en) * 2017-02-10 2019-09-20 赢创德固赛有限公司 Oral care composition containing at least one biosurfactant and fluoride
CN113081916A (en) * 2021-04-08 2021-07-09 金华诺慈生物科技有限公司 A toothpaste containing horse chestnut extract for periodontal repair

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101132761A (en) * 2004-12-29 2008-02-27 高露洁-棕榄公司 Oxidation resistant dentifrice compositions
CN110267641A (en) * 2017-02-10 2019-09-20 赢创德固赛有限公司 Oral care composition containing at least one biosurfactant and fluoride
CN110123702A (en) * 2019-06-17 2019-08-16 中山市多美化工有限公司 A kind of toothpaste and preparation method thereof containing hyaluronic acid and trehalose
CN113081916A (en) * 2021-04-08 2021-07-09 金华诺慈生物科技有限公司 A toothpaste containing horse chestnut extract for periodontal repair

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