CN113350204A - 一种物理与化学结合的控油舒缓摇摇爽肤水及其制备方法 - Google Patents
一种物理与化学结合的控油舒缓摇摇爽肤水及其制备方法 Download PDFInfo
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Abstract
本发明公开了一种控油舒缓化妆品组合物,其中,以化妆品组合物的总重量计,该组合物包括:低级多元醇保湿剂1‑15%、多孔型二氧化硅微球体0.1‑5%、用于悬浮分散二氧化硅微球体的悬浮分散剂0.1‑2%、用于抑制5α‑还原酶的控油成分0.01‑5%、用于舒缓抗敏的成分0.01‑5%、以及余量的水。本发明采用无机悬浮分散剂与二氧化硅微球体相配合,既促进二氧化硅微球体的分散,又增强化妆品的整体吸附油脂能力,其中的控油舒缓和补水活性成分,可进一步有效地起到控油舒缓的效果。使用本发明的化妆品可吸附脸上的油光,实现哑光效果和控油效果。
Description
技术领域
本发明涉及一种化妆用品,更具体讲,本发明涉及一种利用物理和化学结合的方式进行控油的化妆用品。
背景技术
随着人民生活水平的不断提高,人们对美的追求也不断提高,各种化妆品层出不穷。爽肤水、紧肤水和柔肤水统称为化妆水,都具有稳定肌肤、平衡肌肤酸碱性的功效,但各自的侧重点又不同:爽肤水涂抹的感觉比较清爽,能补充肌肤的水分;紧肤水的最大功效在于细致毛孔,还可以有效平衡油脂分泌;柔肤水相较其他两种“水”而言比较滋润,给予肌肤细致的呵护。一般而言,油性皮肤建议使用紧肤水,健康皮肤使用爽肤水,干性皮肤使用柔肤水。对混合皮肤来说,T字部位使用紧肤水,其它部位使用柔肤水和爽肤水皆可。敏感皮肤则可以选用敏感水、修复水,而要想美白的话就可以选用美白化妆水。总之,自己想要达到什么样的效果,就选择具有相应功效的“水”。
现有技术中,中国专利申请CN201910513760.5公开了一种含有甜菜碱水杨酸离子液体的爽肤水及其制备方法,该爽肤水的制备原料中含有甜菜碱水杨酸离子液体、溶剂、增稠剂、保湿剂、皮肤调理剂、表面活性剂和pH调节剂。该专利申请认为,甜菜碱水杨酸的离子液体,具有补水保湿抗菌抗氧化效果,并能增强其他皮肤调理剂溶解性和吸收的效果。其采用的增稠剂包括透明黄原胶和U21,保湿剂包括海藻糖、甘油、1,2-己二醇、1,3-丁二醇和A631,皮肤调理剂包括烟酰胺和P10提取物,表面活性剂包括聚谷氨酸钠,pH调节剂为三乙醇胺。
中国专利申请CN201811142292.7公开了一种可用喷头喷出的半固体爽肤水及其制备方法,其包括增稠剂琼脂糖2~6份、聚甘油类润肤剂2~8份、对羟基苯乙酮2~10份、玫瑰4~10份、甘油6~12份、茉莉精油3~7份、酒精1~5份、60~80份蒸馏水。该专利申请选择具有较强交联作用且对温度不敏感的增稠剂琼脂糖,琼脂糖通过其羟基舒展形成空间立体结构,从而做出冰沙的外观,且羟基结合的化学键在常规仓储和使用温度下不容易被打开,对温度不敏感,又由于喷头的瞬间剪切的机械力较强,能够将化学键切断,使得水和其它滋养成分独立成每一个小雾滴,能够更方便为肌肤所吸收。
中国专利申请CN201610753322.2公开了一种美白保湿精华液,其包括相宜本草红景天幼白爽肤水5-8份、丝瓜水6-9份、樱桃汁4-7份、蜂蜜1-3份、珍珠粉0.5-1.5份、甘油7-11份、增稠剂0.1-0.5份、杜仲3-6份、水30-40份,该申请并没有公开其所采用的增稠剂为何物。
中国专利申请CN201710098192.8公开了一种爽肤水,其包括保湿剂10.1-31.5%、植物提取物0.5-5%、石墨烯量子点0.5-5%、增稠剂0.4-0.8%、乳化剂0.4-0.8%、EDTA二钠0.01-0.1%。该申请认为,石墨烯量子点有良好的吸附特性和促渗作用,能够吸附皮肤表面的污物和各种有毒物质,快速将保湿剂和植物提取物向肌肤角质层、真皮层渗透,将爽肤水中所含营养成分导入,补水保湿,并且起到清洁肌肤,抑制致病菌生长的作用。其所采用的增稠剂为卡波姆,调理剂为尿囊素,乳化剂为三乙醇胺。
由于皮肤中有大量的皮脂腺,皮脂腺分泌的油脂经过毛囊皮脂腺导管到达皮肤表面。然而当外界因素(紫外线、污染、辐射等)或内在因素(激素)刺激影响皮脂腺时,会导致油脂过度分泌,皮肤看起来油光满面,毛孔粗大,严重者则有唑疮、粉刺、玫瑰唑疮、脂溢性皮炎等。因此,控油型爽肤水应运而生。例如,中国专利申请CN201610130088.8公开了一种控油型爽肤水及其制备方法,其包括食用盐0.9%、水98.9%、增稠剂0.2%,而增稠剂则包含硅藻泥15%、碳颗粒5%、米粉20%、水60%。然水中的米粉等物质不易存放,而皮肤上的食盐会带来一定的不适感。该专利申请采用硅藻泥和碳颗粒,利用其对油脂的吸附能力,进行物理控油。
再如,中国专利CN201611167727.4也公开了一种控油爽肤水及其制备方法,该控油爽肤水包括:二氧化硅微球体0.1-5%,保湿剂3-15%,多糖类化合物0.5-8%,蒙脱土0.1-5%,水75-93%。该专利也是利用硅石对油脂的吸附能力,进行物理控油。对于这种物理控油的爽肤水,吸附油脂的物质多为无机矿物质或其改性物,其在水中的快速、均匀地分散,是一难题。
另外,仅仅对皮肤分泌的油脂进行吸附,是一种治标不治本的方法,而且过量吸附介质的使用,会对皮肤带来一定的不爽感觉。如果能对油脂的分泌进行抑制、以减少油脂的分泌,也是控油的一种方式,但油脂分泌是人体正常的代谢过程,过分干预会带来其它的问题。
因此,有必要提供一种新型的控油爽肤水,其既利用物理控油、改进物理吸附介质的分散,又结合化学方法,减少油脂的分泌,同时综合性能优良,不含致敏成分。
发明内容
本发明的目的是提供一种利用物理吸附与化学抑制相结合的控油型化妆水,该控油舒缓化妆品组合物既利用物理方法吸附皮肤表面的油脂,改善油亮外观,又利用抑制5α-还原酶的化学成分,减少油脂分泌,来达到控油的效果。麦角硫因抵御紫外线和清除自由基)
为了实现上述本发明的发明目的,本发明提供了一种控油舒缓化妆品组合物,其中,以该组合物的总重量计,该组合物包括:低级多元醇保湿剂1-15%、用于吸附油脂的多孔型二氧化硅微球体0.1-5%、用于悬浮分散二氧化硅微球体的悬浮分散剂0.1-2%、用于抑制5α-还原酶的控油成分0.01-5%、用于舒缓抗敏的成分0.01-5%、以及余量的水。
在本发明上述的化妆品组合物中,所选择的悬浮分散剂优选为无机的悬浮分散剂,因为相对于大分子的有机悬浮分散剂,无机的悬浮分散剂更会给皮肤带来爽滑的感觉,而且这种悬浮分散剂散布在皮肤表面,还会给皮肤带来一定保护作用,如防晒防紫外辐射等,同时也会有相当的吸附油脂的能力。
优选地,无机悬浮分散剂占化妆品组合物的0.3-1%。
例如,本发明的这种无机悬浮分散剂可以是硅酸镁锂,但并不局限于硅酸镁锂。硅酸镁锂具有增稠性和触变性,且吸附能力强,将其用于化妆品,能提高化妆品的粘度、悬浮性、保稠性、保湿性、润滑性等,连同上述的吸附性能,能增强化妆品的附着力。硅酸镁锂配合二氧化硅微球体一起使用,除了会增加二氧化硅微球体在液体中如水中的悬浮分散能力之外,还具有协同增加油脂吸附能力和附着能力的意想不到的技术效果。
一般而言,硅酸镁锂为三八面体层状硅酸盐物质,硅酸镁锂的理论化学成分:SiO253%-60%、MgO 24%-30%、Na2O 2.5%-3.0%、Li2O 0.5%-1.0%。单位晶胞由两层Si-O四面体夹一层Mg-(O.OH)三八面体组成,晶粒呈不规则片状,片长和宽约(0.3-2.5)μm,片厚约(15-230)nm,是典型人工合成的二维纳米矿物材料。
本发明中,硅酸镁锂可选用硅酸钠镁锂。硅酸钠镁锂是一种低重金属成分合成的多层硅酸盐,并包含无机多磷酸盐分散剂。优选采用外观为自由流动的白色粉末、堆密度(bulk density)大约在1000kg/m3、比表面(BET)在270-390m2/g之间的硅酸钠镁锂。较佳的比表面(BET)在300-360m2/g之间。例如可以选用美国德克萨斯Southern Clay Products,Inc.生产的Laponite XLS,或者选用德国BYK-Chemie GmbH生产的Laponite-XLS XR。这种硅酸钠镁锂在水中会成为水化合物及膨胀,变成无色透明低黏性胶状物。在水中10%的浓度可维持24小时的自由流体状态。加上少量的电解质便可快速形成流变胶。
发明人的实验发现(参见具体实施方式),硅酸镁锂配合二氧化硅微球体一起使用,具有意想不到的悬浮分散效果。
在本发明的化妆品组合物中,所采用的多孔型氧二化硅微球体为改性的二氧化硅,具有中空且多孔的球形结构,这种结构能够增加球体的比表面积,增加吸油量,还能提供粉状质感和丝滑触感,让化妆品组合物的肤感得到提升,清爽丝滑不黏腻。二氧化硅微球体的粒径范围为2-12μm,吸油量为60-210mL/100g。
实际上,二氧化硅微球体的粒径与其吸油量是相关的,例如当其平均粒径在2μm,其吸油量为90-130mL/100g之间;平均粒径在7μm,吸油量60-170mL/100g之间;平均粒径在12μm,吸油量在140-210mL/100g之间。较小的二氧化硅微球体会感到湿润,而较大的会感到比较干燥,小的二氧化硅微球体相较大颗粒的而言,更适用于护肤产品。优选地,二氧化硅微球体的平均粒径为7μm,吸油量60-170mL/100g之间。当二氧化硅微球体的平均粒径>7μm时,容易搓泥,当二氧化硅微球体的平均粒径<7μm时,粉质太轻,因此优选平均粒径为7μm。
优选地,在本发明的化妆品组合物中,二氧化硅微球体的重量百分占比为0.5-2.5%。二氧化硅微球体的商品较多,例如可选择韩国先进化学生产的型号为SUNSIL-130L的二氧化硅微球体。
在本发明的化妆品组合物中,由于硅酸镁锂和二氧化硅微球体均具有优异的吸附油脂的能力,这样在使用时会吸附脸上的油光,从而达到哑光效果和控油效果。
虽然本领域经常使用低级醇类作为保湿剂,但在本发明的化妆品组合物中,优选采用的低级多元醇作为保湿剂,更优选的是选自如下一组的一种以上的低级多元醇:甘油、1,3-丁二醇、1,2-丙二醇、1,3-丙二醇、甲基丙二醇、双甘油和二丙二醇。优选地,低级多元醇保湿剂占化妆品组合物的2-10%;更优选地,低级多元醇保湿剂占化妆品组合物的3-8%。
在本发明的化妆品组合物中,用于抑制5α-还原酶的控油成分的选择十分重要。经过综合评价和实验考察,本发明中用于抑制5α-还原酶的控油成分,优选为选自如下一组的一种以上:北美金缕梅提取物、壬二酸、黄檗树皮提取物、水杨酸和乳糖酸。其中:
虽然药草圣典中记载金缕梅有舒缓、收敛、抗菌的效果,但我们发现金缕梅还具有调节油脂分泌、保湿及净白作用,特别是对于油性皮肤,其能好迅速渗入皮肤,由内而外全面调节肌肤,平衡皮肤PH值及油脂分泌,净化毛孔,修复受损的肌肤,有效调节舒张的毛孔,明显收敛粗毛孔,防止黑头、粉刺产生,使肌肤快速呈现细腻、光滑、紧致状态。金缕梅具有收敛、镇定皮肤的效果,而且其深层清洁的功效可使肌肤抗老化;
黄檗(PHELLODENDRON AMURENSE)树皮提取物含有生物碱、黄柏酮、黄柏内酯、白藓交酯,在祛痘方面有吸收杂质和有控制过度的油脂达到解毒和抗菌的效果,可以使皮肤深处达到一个好的更新作用;
壬二酸是二元羧酸,能够抑制90%的5-αH-还原酶,这种还原酶会参与雄激素的形成。壬二酸是由糠秕马拉色菌产生(也称为皮屑芽孢菌)的一种天然物质,糠秕马拉色菌是一种普通皮肤上产生的酵母菌。壬二酸也能在小麦、黑麦和大麦上自然产生。壬二酸通过抑制皮肤上导致粉刺细菌的生长以及清洁皮肤的毛孔,来治疗轻度或中度痤疮,例如黑头痤疮或炎性痤疮;
水杨酸是一种β羟基酸,其作为角质软化剂时,通过溶解角质间的粘合质,使角质层的老废角质脱落,去除积聚过厚的角质层来促进新陈代谢。水杨酸可作用于毛囊壁细胞,清除黑头粉刺,改善毛孔堵塞情况,同时能抑制痤疮丙酸杆菌、金黄色葡萄球菌等,有效改善和治疗痤疮改善日晒引起的老化,淡化色斑;
乳糖酸在人体中存在,被称为第三代果酸,是由一分子半乳糖和一分子葡萄糖酸通过醚键连接起来的乳糖葡萄糖基上C1被氧化后所得的一种羟基有机酸。其可通过活化类固醇硫酸酯酶和丝氨酸蛋白酶降解桥粒,破坏角质层细胞间的连接(桥粒),松解对接在皮脂腺开口处的角化形成细胞,纠正毛囊上皮角化异常,加速表皮细胞更新,促进皮肤新陈代谢(细致毛孔,亮白),抑制粉刺。
优选地,用于抑制5α-还原酶的控油成分占本发明化妆品组合物的0.05-2.5%;更优选地,用于抑制5α-还原酶的控油成分占本发明化妆品组合物的0.05-1.0%。
在本发明的化妆品组合物,其中,所采用的用于舒缓抗敏的成分优选为选自如下一组的一种以上的成分:尿囊素、甘草酸二钾、泛醇、积雪草提取物、虎杖根提取物、黄岑根提取物、茶叶提取物、光果甘草提取物、母菊花提取物、和迷迭香叶提取物。
优选地,用于舒缓抗敏的成分占本发明化妆品组合物的0.05-2.5%;更优选地,用于舒缓抗敏的成分占本发明化妆品组合物的0.1-2.0%。
除了上述的成分外,本发明的化妆品组合物还可以进一步包括其它的功能成分。例如,本发明的化妆品组合物进一步包括选自如下一组的一种以上的保湿剂:PCA钠、丝氨酸、甘油聚醚-26、和甘油葡糖苷。此类保湿剂的含量一般控制在0.01-5%的范围内,优选控制在0.01-1%的范围内。
鉴于燃油机动车的保有量越来越大,空气中因矿物燃料特别是各种油品燃烧不完全所生产的自由基越来越多,人们罹患各种皮肤病的风险也越来越高。因此,在本发明的化妆品组合物中,可进一步包括0.01-2%(优选0.01-0.5%)的、选自如下一组的一种以上的对抗自由基(自由基捕获剂)的成分:麦角硫因、茶叶提取物和二裂酵母发酵产物滤液,特别是麦角硫因。
麦角硫因是一种稀有的天然氨基酸,是机体内重要的生理活性物质,但人体不能自身合成,必须靠外来补充。其通过人体的转运蛋白OCTN1进入到细胞内部以及线粒体中,起到对抗ROS自由基的作用;另外,其还对紫外线以及可见光的辐射的损伤有很好的细胞保护作用,提高细胞的存活率,可以抑制MMP-1、TNF-α(肿瘤坏死因子)的表达,能调节细胞内的氧化还原反应,参与细胞内能量调节以及生理保护剂等多功能,在体内抗氧化,清除自由基,防止紫外辐射损伤。
本发明的化妆品组合物可进一步包括0.01-2.5%、优选0.03-1%、更优选0.03-0.3%的螯合剂,所采用的螯合剂可选自EDTA二钠、EDTA三钠、EDTA四钠、NTA三钠等任何化妆品中常用的螯合剂。
一般来说,大多数的化妆品均含有一定量的防腐剂。在本发明的化妆品组合物一般要含有0.01-2%、优选0.01-1%、更优选0.05-0.2%的防腐剂。可选择的防腐剂及防腐增效剂包括苯氧乙醇、戊二醇、己二醇、对羟基苯乙酮、辛甘醇等任何化妆品中常用的防腐剂。
另外,本发明的化妆品组合物中还可含有0.1-1%的氯化钠、0.001%-0.5%的精油、0.01-0.5%的增溶剂(如PEG-40氢化蓖麻油、PPG-26-丁醇聚醚-26等)和/或其它的功能成分。
但是,本发明化妆品组合物一个重要的技术特征是,化妆品组合物中不含矿物油、香精及色素这些可能引起过敏的成分,也不添加其它不必要的成分。
作为本发明化妆品组合物的一种产品形式,该化妆品组合物可以是各种化妆水,如紧肤水、爽肤水、柔肤水等,特别是爽肤水。
优选地,当本发明的化妆品组合物是爽肤水时,可以是创新的水粉分离的摇摇体系,此时,本发明的化妆品组合物就是一种物理吸附与化学抑制相结合的控油舒缓摇摇爽肤水。
另一方面,本发明还提供了制备上述化妆品组合物的制备方法。作为一种具体实施方式,其具体操作过程可包括如下的步骤:
(1)将A相原料加入调配缸,搅拌均匀,升温至80-85℃,保温搅拌活化该原料;
(2)调配缸降温至45℃,将B相原料加入调配缸,搅拌均匀;
(3)调配缸降温至40℃,将C相原料加入调配缸,搅拌均匀,出料;
其中,A相原料为悬浮分散剂,B相原料为低级多元醇保湿剂、用于抑制5α-还原酶的控油成分、用于舒缓抗敏的成分、防腐剂、以及任选的其它保湿剂、对抗自由基的成分、螯合剂、增溶剂、精油、氯化钠等;C相原料为二氧化硅微球体。
本发明采用无机悬浮分散剂与二氧化硅微球体相配合,一方面可以促进二氧化硅微球体的分散,另一方面可以增强化妆品的整体吸附油脂能力;其中的控油舒缓和补水活性成分,可进一步有效地起到控油舒缓的效果,而且该化妆品组合物不含矿物油、香精及色素这些可能引起过敏的成分,不添加其它不必要的成分,使用其可吸附脸上的油光,实现哑光效果和控油效果。
下面,结合附图和具体实施方式对本发明作进一步的说明,但这些具体实施方式只是针对本发明某些特定的具体实施方式的说明而已,并非是对本发明的限定。
附图说明
图1是不同配方时粉体的悬浮分散照片;
图2显示的是皮肤油脂含量测试中样品与对照结果的图形分析。
具体实施方案
制备实施例1
按照下列过程制备本发明的化妆品组合物:
(1)将A相原料加入调配缸(含配方量的去离子水),搅拌均匀,升温至80-85℃,保温搅拌活化该原料;
(2)调配缸降温至45℃,将B相原料加入调配缸,搅拌均匀;
(3)调配缸降温至40℃,将C相原料加入调配缸,搅拌均匀,出料;
其中,A相原料为占最终产物0.5%的、Southern Clay Products,Inc.生产的Laponite XLS(硅酸钠镁锂);
B相原料为:占最终产物2%的二丙二醇、0.2%的尿囊素、0.08%的甘草酸二钾、0.5%的泛醇、0.1%的积雪草提取物、0.1%的虎杖根提取物、0.1%的黄岑根提取物、0.1%的茶叶提取物、0.1%的光果甘草提取物、0.1%的母菊花提取物、0.1%的迷迭香叶提取物、1%的PCA钠、0.1%的丝氨酸、1.5%的甘油聚醚-26、0.5%的甘油葡糖苷、5%的北美金缕梅提取物、0.2%的壬二酸、0.5%的黄檗树皮提取物、0.05%的EDTA二钠、0.1%的麦角硫因、0.5%的二裂酵母发酵产物滤液、1%的氯化钠、0.01%的苦橙(CITRUS AURANTIUM AMARA)花油、0.5%的1,2-己二醇、0.45%的苯氧乙醇、0.1%的辛甘醇、0.08%的PPG-26-丁醇聚醚-26;
C相原料为占最终产物1.5%的、韩国先进化学生产的型号为SUNSIL-130L的二氧化硅微球体。
制备实施例2
制备过程同实施例1,但配方为:
A相原料为占最终产物0.6%的、德国BYK-Chemie GmbH生产的Laponite-XLS XR(硅酸钠镁锂);
B相原料为:占最终产物3%的丁二醇、0.15%的尿囊素、0.05%的甘草酸二钾、0.5%的泛醇、0.1%的积雪草提取物、0.1%的虎杖根提取物、0.1%的黄岑根提取物、0.1%的茶叶提取物、0.1%的光果甘草提取物、0.1%的母菊花提取物、0.1%的迷迭香叶提取物、1.5%的PCA钠、0.3%的丝氨酸、1.5%的甘油聚醚-26、0.5%的甘油葡糖苷、4%的北美金缕梅提取物、0.2%的水杨酸、0.1%的黄檗树皮提取物、0.05%的EDTA二钠、0.2%的麦角硫因、3%的二裂酵母发酵产物滤液、1%的氯化钠、0.01%的精油、0.5%的1,2-己二醇、0.45%的苯氧乙醇、0.1%的辛甘醇、0.08%的PPG-26-丁醇聚醚-26;
C相原料为占最终产物1.5%的、韩国先进化学生产的型号为SUNSIL-130L的二氧化硅微球体。
制备实施例3
制备过程同实施例1,但配方为:
A相原料为占最终产物0.45%的、德国BYK-Chemie GmbH生产的Laponite-XLS XR(硅酸钠镁锂);
B相原料为:占最终产物3%的丙二醇、0.2%的尿囊素、0.08%的甘草酸二钾、1%的泛醇、0.1%的积雪草提取物、0.1%的虎杖根提取物、0.1%的黄岑根提取物、0.1%的茶叶提取物、0.1%的光果甘草提取物、0.1%的母菊花提取物、0.1%的迷迭香叶提取物、1.5%的PCA钠、0.3%的丝氨酸、2%的甘油聚醚-26、0.5%的甘油葡糖苷、5%的北美金缕梅提取物、0.2%的壬二酸、0.3%的乳糖酸、0.5%的黄檗树皮提取物、0.05%的EDTA二钠、0.5%的麦角硫因、5%的二裂酵母发酵产物滤液、1%的氯化钠、0.01%的精油、0.5%的苯氧乙醇、0.45%的对羟基苯乙酮、0.08%的PPG-26-丁醇聚醚-26;
C相原料为占最终产物1.5%的、韩国先进化学生产的型号为SUNSIL-130L的二氧化硅微球体。
分散对比实验
按照上述制备实施例的制备过程、按下列表1中的配方制备化妆品组合物进行对比实验,统一用对比例#表示,其中对比例1-3为不采用无机悬浮分散剂的对照组,对比例4-9为采用无机悬浮分散剂的对照组,具体分散情况见图1中照片:
表1
从表1和图1可以发现:硅酸钠镁锂和二氧化硅微球体的比例会影响粉的高度,硅酸钠镁锂的重量比为0%时,粉体(悬浮分散剂+二氧化硅)悬不住,直接沉下在最底层;硅酸钠镁锂硅酸钠镁锂的重量比≥1%时,粉体不易沉不下去;当选择粉体的高度为30%-70%时,则硅酸钠镁锂的重量比为0.3-1%。二氧化硅微球体的重量比含量越高,粉体的高度会下降,(粉体越重,越往下沉),二氧化硅微球体的重量比≤0.5%时,粉层会显得透明,不够白,二氧化硅微球体的重量比≥2.5%时,粉层的高度会下降,选择粉的高度为30%-70%时,二氧化硅微球体硅酸钠镁锂的重量比为0.5-2.5%。
功效测试实验
申请人委托了上海市天祥质量技术服务有限公司对本发明制备的控油舒缓的化妆品组合物(产品)进行测试:
使用6小时和8小时的控油测试:
使用Sebumeter测试额头油脂含量:
使用前、使用后6小时、使用后8小时共3次按照要求对受试者额头进行测试;参数值越小,油脂含量越低;
产品使用后,相比空白对照区域,测试区域油脂含量降低具有显著性,表示该受试样品具有控油的效果。
测试结果如下表2:
表2样品区与对照区对比结果(测试人数:33人)
注:1.显著性“ns”表示P>0.05,“**”表示0.001≤P<0.01,“***”表示P<0.001。
结论如下:
本受试者人群(33人),单次使用测试样品,样品区与对照区测试结果表明:
样品区域使用测试样品6小时后,皮肤油脂含量减少值显著性大于对照区(P<0.001),表示测试样品具有6小时控油效果;
样品区域使用测试样品8小时后,皮肤油脂含量减少值显著性大于对照区(P=0.002),表示测试样品具有8小时控油效果。
皮肤油脂含量测试结果:
1.1测试结果描述统计量
1.1.1.原始数据描述统计量,见表3:
表3原始数据描述统计量(单位μg/cm2)
1.1.2.改变值描述统计量,见表4:
表4改变值描述统计量(单位μg/cm2)
1.2统计结果分析,见表5、表6:
表5T0h各区域角质层水分含量比较分析结果
表6样品与对照品比较分析结果
1.3样品与对照结果图形分析,见图2:
其中,“ns”表示P>0.05,“**”表示0.001≤P<0.01,“***”表示P<0.001;
与对照相比,皮肤油脂含量降低越多,表示产品控油效果越好。
Claims (9)
1.一种控油舒缓化妆品组合物,其中,以所述化妆品组合物的总重量计,该化妆品组合物包括:低级多元醇保湿剂1-15%、用于吸附油脂的多孔型二氧化硅微球体0.1-5%、用于悬浮分散所述二氧化硅微球体的悬浮分散剂0.1-2%、用于抑制5α-还原酶的控油成分0.01-5%、用于舒缓抗敏的成分0.01-5%、以及余量的水。
2.如权利要求1所述的化妆品组合物,其中,所述的悬浮分散剂为硅酸钠镁锂,所述的硅酸钠镁锂是一种低重金属成分合成的多层硅酸盐,并包含无机多磷酸盐分散剂。
3.如权利要求1所述的化妆品组合物,其中,所述的低级多元醇保湿剂选自如下一组的一种以上:甘油、1,3-丁二醇、1,2-丙二醇、1,3-丙二醇、甲基丙二醇、双甘油和二丙二醇。
4.如权利要求1所述的化妆品组合物,其中,所述的用于抑制5α-还原酶的控油成分选自如下一组的一种以上:北美金缕梅提取物、壬二酸、黄檗树皮提取物、水杨酸和乳糖酸。
5.如权利要求1所述的化妆品组合物,其中,所述的用于舒缓抗敏的成分选自如下一组的一种以上:尿囊素、甘草酸二钾、泛醇、积雪草提取物、虎杖根提取物、黄岑根提取物、茶叶提取物、光果甘草提取物、母菊花提取物、和迷迭香叶提取物。
6.如权利要求1所述的化妆品组合物,其中,所述的化妆品组合物进一步包括选自如下一组的一种以上的保湿剂:PCA钠、丝氨酸、甘油聚醚-26、和甘油葡糖苷。
7.如权利要求1所述的化妆品组合物,其中,所述的化妆品组合物进一步包括0.01-5%的、选自如下一组的一种以上的抗氧化成分:麦角硫因、茶叶提取物和二裂酵母发酵产物滤液。
8.如权利要求1所述的化妆品组合物,其中,所述的多孔型二氧化硅微球体的粒径范围为2-12μm,吸油量为60-210mL/100g。
9.如权利要求1所述的化妆品组合物,其中,所述的化妆品组合物是化妆水,特别是爽肤水。
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