CN113332163A

CN113332163A - Two-component essence and preparation method thereof

Info

Publication number: CN113332163A
Application number: CN202110582133.4A
Authority: CN
Inventors: 高博闻; 王垚; 钟一竹竹; 高鹿鸣
Original assignee: Alcohol International Biotechnology Beijing Co ltd
Current assignee: Alcohol International Biotechnology Beijing Co ltd
Priority date: 2021-05-27
Filing date: 2021-05-27
Publication date: 2021-09-03
Anticipated expiration: 2041-05-27
Also published as: CN113332163B

Abstract

The invention relates to a two-component essence and a preparation method thereof, wherein the two-component essence consists of a hydrogel A component and an essence B component, wherein the hydrogel A component is an aqueous solution containing an amphiphilic polymer; the essence B comprises the following components in parts by weight: deionized water, a surfactant, a humectant, glycerin, a ginseng root extract, dipotassium glycyrrhizinate, essential oil, sodium alginate, carnosine, acetyl hexapeptide-8, palmitoyl pentapeptide-4, oligopeptide-1 and an antioxidant. The two-component essence disclosed by the invention is fused into transparent liquid, can be smeared as moisturizing water and also can be used as a mask liquid, the component B contains active ingredients, and a gel film is formed on the surface of skin, so that the essence can be quickly absorbed and moisturized, and the effects of moisturizing, deep cleaning, soothing the skin after sun drying and resisting oxidation are achieved.

Description

Two-component essence and preparation method thereof

Technical Field

The invention relates to the field of cosmetics, in particular to a two-component essence and a preparation method thereof.

Background

The mask is a common skin care product, and is usually used after the face is cleaned, the mask is covered on the face for a period of time to be isolated from the outside air, pores on the face are expanded to promote metabolism, absorb nutrition in the mask and remove metabolites in the epidermis. In the existing facial mask package, essence soaks facial mask paper, and when the facial mask is covered on the face, the face can absorb effective components of the essence. However, the existing essence has single efficacy, and cannot meet more requirements of consumers on the beauty and skin care of facial mask essence. There are also many available smearing type gel masks which do not need mask paper, but the thick texture of the gel is not beneficial to the release of the essence. However, covering the skin surface with a gel film for a long time is not beneficial to the respiration and metabolism of skin cells.

Disclosure of Invention

The invention aims to solve the problems and provides the two-component essence and the preparation method thereof.

The purpose of the invention is realized by the following technical scheme:

a two-component essence consists of a hydrogel A component and an essence B component, wherein the hydrogel A component is a thermotropic hydrogel solution which is an aqueous solution containing an amphiphilic polymer and is liquid before use, and a gel film with a skin care function is formed on the surface of skin after use;

the essence B comprises the following components in parts by weight: 100 parts of deionized water, 1-5 parts of surfactant, 0.01-0.05 part of humectant, 0.1-0.5 part of glycerol, 0.01-0.05 part of ginseng root extract, 0.01-0.05 part of dipotassium glycyrrhizinate, 0.1-0.5 part of essential oil, 2-5 parts of sodium alginate, 0.1-0.3 part of carnosine, 0-80.005-0.02 part of acetyl hexapeptide, 40.05-0.1 part of palmitoyl pentapeptide, 10.1-0.5 part of oligopeptide and 0.05-0.1 part of antioxidant.

Preferably, the essence B component comprises the following components in parts by weight: 100 parts of deionized water, 2-4 parts of surfactant, 0.02-0.04 part of humectant, 0.2-0.4 part of glycerol, 0.02-0.04 part of ginseng root extract, 0.02-0.04 part of dipotassium glycyrrhizinate, 0.2-0.4 part of essential oil, 2-4 parts of sodium alginate, 0.1-0.3 part of carnosine, 0-80.01-0.02 part of acetyl hexapeptide, 40.05-0.08 part of palmitoyl pentapeptide, 10.2-0.4 part of oligopeptide and 0.05-0.08 part of antioxidant.

Preferably, the essence B component comprises the following components in parts by weight: 100 parts of deionized water, 3 parts of surfactant, 0.03 part of humectant, 0.3 part of glycerol, 0.03 part of ginseng root extract, 0.03 part of dipotassium glycyrrhizinate, 0.3 part of essential oil, 3 parts of sodium alginate, 0.2 part of carnosine, 80.02 parts of acetyl hexapeptide, 40.06 parts of palmitoyl pentapeptide, 10.3 parts of oligopeptide and 0.06 part of antioxidant.

Preferably, the aqueous solution of the amphiphilic polymer comprises pure water and normal saline, the pH is between 4 and 6, and essence can also be added.

Preferably, the amphiphilic polymer is an amphiphilic block copolymer which is composed of polyethylene glycol as a hydrophilic block and biodegradable polyester as a hydrophobic block, and the number average molecular weight of the polyethylene glycol is 800-1500.

Preferably, the polyester comprises any one of poly D-lactide, polyglycolide, poly epsilon-caprolactone, polyesteramide and polyetherester.

Preferably, the surfactant is selected from one or more of polysorbate-20, PEG-7 glyceryl cocoate, sodium cocoyl glutamate.

Preferably, the humectant is selected from one or more of sodium hyaluronate, sodium polyglutamate, polyethylene glycol-8 and propylene glycol.

Preferably, the essential oil is selected from one or more of lavender essential oil, tea tree essential oil, rose geranium essential oil, chamomile essential oil, jasmine essential oil, clove essential oil or cypress essential oil;

the antioxidant is selected from at least one of di-tert-butyl-p-cresol, tert-butyl hydroxyanisole, gallic acid ester and benzotriazole-based sodium styrene-butadiene phenol sulfonate.

A preparation method of a two-component essence comprises the following steps:

synthesizing an amphiphilic polymer, preparing the amphiphilic polymer into a block copolymer aqueous solution at a low temperature, and refrigerating for storage;

the preparation method of the essence B component comprises the following steps:

(1) preparing materials according to a formula, heating deionized water, preserving heat, sterilizing, cooling to 50-60 ℃, sequentially adding a surfactant, a humectant, glycerol and essential oil, and uniformly stirring;

(2) cooling to 40-50 deg.C, sequentially adding dipotassium glycyrrhizinate, sodium alginate and antioxidant, and stirring;

(3) cooling to below 30 deg.C, adding Ginseng radix extract, carnosine, acetyl hexapeptide-8, palmitoyl pentapeptide-4, and oligopeptide-1, and stirring.

When the two-component essence is used, the essence B component is firstly smeared on the cleaned face, and then the hydrogel A component is smeared.

Compared with the prior art, the invention has the following beneficial effects:

the component B of the essence comprises oligopeptide compositions such as carnosine, acetyl hexapeptide-8, palmitoyl pentapeptide-4 and oligopeptide-1, is beneficial to improving lymphatic circulation and microcirculation and improving permeability, has the effects of reducing free radicals, glycosylation and lipid oxidation, and can increase the growth of skin cells and promote the synthesis of collagen after being compounded with an antioxidant, sodium alginate and a humectant. The hydrogel A component of the invention is used as a temperature-sensitive physical gel, micelles taking polyether segments as hydrophilic shells and polyester segments as hydrophobic cores can be spontaneously formed at low temperature, the micelles are flowable liquid, the hydrophilicity of the polyether segments is reduced along with the rise of temperature, and the micelles spontaneously aggregate under the drive of hydrophobic interaction to form a percolation micelle network which is in a gel state. Therefore, after the component B of the essence is applied to the face, the hydrogel component A is used, the side which is in contact with the skin rapidly gelatinizes and then precipitates, and the essence can be locked, so that the release and absorption of the essence are promoted.

Detailed Description

The present invention is described in detail below with reference to specific examples, but the present invention is not limited thereto in any way.

Example 1

A two-component essence comprises a hydrogel component A and an essence component B.

The hydrogel A component is a thermotropic hydrogel solution which is an aqueous solution containing amphiphilic polymers, the hydrogel A component is liquid before use, a gel film with a skin care function is formed on the surface of skin after use, the aqueous solution of the amphiphilic polymers comprises normal saline, and the pH value is between 4 and 6;

the amphiphilic polymer is an amphiphilic block copolymer which is formed by polyethylene glycol serving as a hydrophilic block and biodegradable polyester serving as a hydrophobic block, the number average molecular weight of the polyethylene glycol is 800-1500, and the polyester comprises any one of poly D-lactide, polyglycolide, poly epsilon-caprolactone, polyesteramide and polyetherester.

The preparation method comprises the steps of adding polyethylene glycol with the number average molecular weight of 1200 into a reactor, heating to 115 ℃, vacuumizing while stirring, then adding D-lactide, adding a catalyst stannous octoate, heating to 145 ℃, reacting in an argon atmosphere, vacuumizing to remove unreacted monomers and low-boiling-point products after the reaction is finished, pouring the reaction products into hot water while hot, washing for several times, freeze-drying to obtain the amphiphilic polymer, and adding the amphiphilic polymer into an aqueous solution at low temperature to obtain a polymer water system.

The essence B comprises the following components in parts by weight: 100 parts of deionized water, 1 part of surfactant, 0.01 part of humectant, 0.1 part of glycerol, 0.01 part of ginseng root extract, 0.01 part of dipotassium glycyrrhizinate, 0.1 part of essential oil, 2 parts of sodium alginate, 0.1 part of carnosine, 80.005 parts of acetyl hexapeptide, 40.05 parts of palmitoyl pentapeptide, 10.1 parts of oligopeptide and 0.05 part of antioxidant;

wherein the surfactant is polysorbate-20; the humectant is sodium hyaluronate; the essential oil is lavender essential oil; the antioxidant is di-tert-butyl-p-cresol.

The preparation method of the component B of the essence comprises the following steps:

(1) preparing materials according to a formula, heating deionized water, preserving heat, sterilizing, cooling to 55 ℃, sequentially adding a surfactant, a humectant, glycerol and essential oil, and uniformly stirring;

(2) cooling to 45 deg.C, sequentially adding dipotassium glycyrrhizinate, sodium alginate and antioxidant, and stirring;

(3) cooling to below 30 deg.C, adding Ginseng radix extract, carnosine, acetyl hexapeptide-8, palmitoyl pentapeptide-4, and oligopeptide-1, and stirring;

example 2

Adding polyethylene glycol with the number average molecular weight of 1300 into a reactor, heating to 120 ℃, vacuumizing while stirring, then adding glycolide, adding a catalyst stannous octoate, heating to 145 ℃, reacting in an argon atmosphere, vacuumizing to remove unreacted monomers and low-boiling-point products after the reaction is finished, pouring the reaction products into hot water while hot, washing for several times, freezing and drying to obtain an amphiphilic polymer, and adding the amphiphilic polymer into an aqueous solution at a low temperature to obtain a polymer water system.

The essence B comprises the following components in parts by weight: 100 parts of deionized water, 5 parts of surfactant, 0.05 part of humectant, 0.5 part of glycerol, 0.05 part of ginseng root extract, 0.05 part of dipotassium glycyrrhizinate, 0.5 part of essential oil, 5 parts of sodium alginate, 0.3 part of carnosine, 80.02 parts of acetyl hexapeptide, 40.1 parts of palmitoyl pentapeptide, 10.5 parts of oligopeptide and 0.1 part of antioxidant.

Wherein the surfactant is PEG-7 glyceryl cocoate; the humectant is sodium polyglutamate; the essential oil is tea tree essential oil; the antioxidant is tert-butyl hydroxy anisole.

The rest is the same as in example 1.

Example 3

Adding polyethylene glycol with the number average molecular weight of 1300 into a reactor, heating to 115 ℃, vacuumizing while stirring, then adding D-lactide, adding a catalyst stannous octoate, heating to 145 ℃, reacting in an argon atmosphere, vacuumizing to remove unreacted monomers and low-boiling-point products after the reaction is finished, pouring the reaction product into hot water to wash for several times while hot, freezing and drying to obtain an amphiphilic polymer, and adding the amphiphilic polymer into an aqueous solution at a low temperature to obtain a polymer water system.

The essence B comprises the following components in parts by weight: 100 parts of deionized water, 2 parts of surfactant, 0.02 part of humectant, 0.2 part of glycerol, 0.02 part of ginseng root extract, 0.02 part of dipotassium glycyrrhizinate, 0.2 part of essential oil, 2 parts of sodium alginate, 0.1 part of carnosine, 80.01 parts of acetyl hexapeptide, 40.05 parts of palmitoyl pentapeptide, 10.2 parts of oligopeptide and 0.05 part of antioxidant.

Wherein the surfactant is sodium cocoyl glutamate; the humectant is sodium hyaluronate; the essential oil is clove essential oil; the antioxidant is tert-butyl hydroxy anisole.

The rest is the same as in example 1.

Example 4

The essence B comprises the following components in parts by weight: 100 parts of deionized water, 4 parts of surfactant, 0.04 part of humectant, 0.4 part of glycerol, 0.04 part of ginseng root extract, 0.04 part of dipotassium glycyrrhizinate, 0.4 part of essential oil, 4 parts of sodium alginate, 0.3 part of carnosine, 80.02 parts of acetyl hexapeptide, 40.08 parts of palmitoyl pentapeptide, 10.4 parts of oligopeptide and 0.08 part of antioxidant.

Wherein the surfactant is sodium cocoyl glutamate; the humectant is sodium polyglutamate; the essential oil is jasmine essential oil; the antioxidant is di-tert-butyl-p-cresol.

The rest is the same as in example 1.

Example 5

The essence B comprises the following components in parts by weight: 100 parts of deionized water, 3 parts of surfactant, 0.03 part of humectant, 0.3 part of glycerol, 0.03 part of ginseng root extract, 0.03 part of dipotassium glycyrrhizinate, 0.3 part of essential oil, 3 parts of sodium alginate, 0.2 part of carnosine, 80.02 parts of acetyl hexapeptide, 40.06 parts of palmitoyl pentapeptide, 10.3 parts of oligopeptide and 0.06 part of antioxidant.

The rest is the same as in example 1.

The two-component essences prepared in examples 1-5 were subjected to application testing.

1. The test products are the two-component essence of the examples 1-5 and the commercially available essence products;

2. a population of subjects, 50 female volunteers between the ages of 30-35 years;

3. the health condition, the skin health of the subject, no allergic history of the skin disease, and the volunteer enrollment standard of the subject are met.

4. The test method comprises the following steps: after the face of the subject is cleaned, the essence liquids of examples 1 to 5 and the similar commercially available essence liquids are randomly used by the volunteers, smeared on the cheeks, observed and experienced the using effect, the number of people giving good comments is recorded, the product is tried for 10 days, and the test evaluation is shown in table 1.

TABLE 1

	Skin finish	Sense of moisture retention	Skin shine
				Example 1	43	42	45
Example 2	44	42	43
				Example 3	46	45	47
Example 4	46	47	45
				Example 5	48	49	46
Commercial essence product	31	33	32

The testers show that the essence disclosed by the invention has better effects on the aspects of skin smoothness, moisturizing feeling, skin brightness and the like, and the effect is better than that of similar products sold in the market.

Compared with the existing facial mask skin care products, such as a facial mask and a smearing type gel facial mask, the facial mask needs to cover the face with facial mask paper full of essence, drops easily when in use, water loss is easily caused after the facial mask is completely dried, the smearing type gel facial mask is thick in texture, clothes are easily stained in daily use, the two facial masks are time-consuming to use, and single in effect, and the requirements of multiple effects of facial mask beauty and skin care and rapid and convenient use of consumers cannot be met. The hydrogel A component is used as a temperature-sensitive physical gel, after the essence B component is smeared on the face, the hydrogel A component is used, one side of the hydrogel A component, which is in contact with the skin, is quickly gelatinized and then precipitated, the essence can be locked, the release and absorption of the essence are promoted, and the defects of the existing mask are effectively avoided.

The embodiments described above are described to facilitate an understanding and use of the invention by those skilled in the art. It will be readily apparent to those skilled in the art that various modifications to these embodiments may be made, and the generic principles described herein may be applied to other embodiments without the use of the inventive faculty. Therefore, the present invention is not limited to the above embodiments, and those skilled in the art should make improvements and modifications within the scope of the present invention based on the disclosure of the present invention.

Claims

1. A two-component essence is characterized by consisting of a hydrogel A component and an essence B component, wherein the hydrogel A component is a thermotropic hydrogel solution which is an aqueous solution containing an amphiphilic polymer, is liquid before use, and forms a gel film with a skin care function on the surface of skin after use;

2. The two-component essence according to claim 1, wherein the B component of the essence comprises the following components in parts by weight: 100 parts of deionized water, 2-4 parts of surfactant, 0.02-0.04 part of humectant, 0.2-0.4 part of glycerol, 0.02-0.04 part of ginseng root extract, 0.02-0.04 part of dipotassium glycyrrhizinate, 0.2-0.4 part of essential oil, 2-4 parts of sodium alginate, 0.1-0.3 part of carnosine, 0-80.01-0.02 part of acetyl hexapeptide, 40.05-0.08 part of palmitoyl pentapeptide, 10.2-0.4 part of oligopeptide and 0.05-0.08 part of antioxidant.

3. The two-component essence according to claim 1, wherein the B component of the essence comprises the following components in parts by weight: 100 parts of deionized water, 3 parts of surfactant, 0.03 part of humectant, 0.3 part of glycerol, 0.03 part of ginseng root extract, 0.03 part of dipotassium glycyrrhizinate, 0.3 part of essential oil, 3 parts of sodium alginate, 0.2 part of carnosine, 80.02 parts of acetyl hexapeptide, 40.06 parts of palmitoyl pentapeptide, 10.3 parts of oligopeptide and 0.06 part of antioxidant.

4. The two-component essence according to claim 1, wherein the aqueous solution of the amphiphilic polymer comprises pure water, physiological saline and has a pH of 4-6, and essence can also be added.

5. The two-component essence of claim 1, wherein the amphiphilic polymer is an amphiphilic block copolymer comprising polyethylene glycol as a hydrophilic block and biodegradable polyester as a hydrophobic block, and the number average molecular weight of the polyethylene glycol is 800-1500.

6. The two-component essence of claim 5, wherein the polyester comprises any one of poly-D-lactide, polyglycolide, poly-epsilon-caprolactone, polyesteramide and polyetherester.

7. A two-component serum according to any one of claims 1-3 wherein the surfactant is selected from one or more of polysorbate-20, PEG-7 glyceryl cocoate, sodium cocoyl glutamate.

8. The two-component essence according to any one of claims 1 to 3, wherein the moisturizer is one or more selected from the group consisting of sodium hyaluronate, sodium polyglutamate, polyethylene glycol-8, and propylene glycol.

9. A two-component essence according to any one of claims 1-3, wherein the essential oil is selected from one or more of lavender essential oil, tea tree essential oil, rose geranium essential oil, chamomile essential oil, jasmine essential oil, clove essential oil, or cypress essential oil;

10. The method of preparing a two-component essence according to any one of claims 1 to 3,

the preparation method of the hydrogel A component comprises the following steps: