CN113318029A - 一种水润化妆水及其制备方法 - Google Patents
一种水润化妆水及其制备方法 Download PDFInfo
- Publication number
- CN113318029A CN113318029A CN202110674915.0A CN202110674915A CN113318029A CN 113318029 A CN113318029 A CN 113318029A CN 202110674915 A CN202110674915 A CN 202110674915A CN 113318029 A CN113318029 A CN 113318029A
- Authority
- CN
- China
- Prior art keywords
- parts
- extract
- mixture
- water
- propylene glycol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000006210 lotion Substances 0.000 title claims abstract description 39
- 230000003020 moisturizing effect Effects 0.000 title claims abstract description 39
- 238000002360 preparation method Methods 0.000 title abstract description 10
- 239000000203 mixture Substances 0.000 claims abstract description 51
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims abstract description 32
- 239000000047 product Substances 0.000 claims abstract description 25
- 229920001184 polypeptide Polymers 0.000 claims abstract description 22
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 22
- 102000004196 processed proteins & peptides Human genes 0.000 claims abstract description 22
- 238000000855 fermentation Methods 0.000 claims abstract description 21
- 230000004151 fermentation Effects 0.000 claims abstract description 21
- 239000006166 lysate Substances 0.000 claims abstract description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 19
- 108010058643 Fungal Proteins Proteins 0.000 claims abstract description 17
- 241001506047 Tremella Species 0.000 claims abstract description 17
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims abstract description 16
- 241001673954 Magnolia sieboldii Species 0.000 claims abstract description 16
- 241000235346 Schizosaccharomyces Species 0.000 claims abstract description 16
- 108010013296 Sericins Proteins 0.000 claims abstract description 16
- 235000020944 retinol Nutrition 0.000 claims abstract description 16
- 229960003471 retinol Drugs 0.000 claims abstract description 16
- 239000011607 retinol Substances 0.000 claims abstract description 16
- 229960000401 tranexamic acid Drugs 0.000 claims abstract description 10
- GYDJEQRTZSCIOI-LJGSYFOKSA-N tranexamic acid Chemical compound NC[C@H]1CC[C@H](C(O)=O)CC1 GYDJEQRTZSCIOI-LJGSYFOKSA-N 0.000 claims abstract description 10
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims abstract description 9
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims abstract description 8
- 239000003906 humectant Substances 0.000 claims abstract description 8
- 239000002537 cosmetic Substances 0.000 claims abstract description 7
- 229960003966 nicotinamide Drugs 0.000 claims abstract description 6
- 235000005152 nicotinamide Nutrition 0.000 claims abstract description 6
- 239000011570 nicotinamide Substances 0.000 claims abstract description 6
- -1 pH adjusters Substances 0.000 claims abstract description 6
- 239000002562 thickening agent Substances 0.000 claims abstract description 5
- 235000008585 Pinus thunbergii Nutrition 0.000 claims abstract description 4
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 4
- 230000003750 conditioning effect Effects 0.000 claims abstract description 4
- 239000000706 filtrate Substances 0.000 claims abstract description 4
- 244000068988 Glycine max Species 0.000 claims abstract description 3
- 235000010469 Glycine max Nutrition 0.000 claims abstract description 3
- 241000186660 Lactobacillus Species 0.000 claims abstract description 3
- 235000008582 Pinus sylvestris Nutrition 0.000 claims abstract description 3
- 241000218626 Pinus sylvestris Species 0.000 claims abstract description 3
- 241000218686 Pinus thunbergii Species 0.000 claims abstract description 3
- 229940039696 lactobacillus Drugs 0.000 claims abstract description 3
- 235000013336 milk Nutrition 0.000 claims abstract description 3
- 239000008267 milk Substances 0.000 claims abstract description 3
- 210000004080 milk Anatomy 0.000 claims abstract description 3
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 claims abstract description 3
- 239000001839 pinus sylvestris Substances 0.000 claims abstract description 3
- 229920005862 polyol Polymers 0.000 claims abstract description 3
- 150000003077 polyols Chemical class 0.000 claims abstract description 3
- 239000003755 preservative agent Substances 0.000 claims abstract description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 84
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 27
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims description 26
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 22
- 238000003756 stirring Methods 0.000 claims description 21
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims description 18
- 244000223977 Tuber melanosporum Species 0.000 claims description 14
- 235000002777 Tuber melanosporum Nutrition 0.000 claims description 14
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims description 13
- 241000972296 Choiromyces meandriformis Species 0.000 claims description 13
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 13
- 108010020346 Polyglutamic Acid Proteins 0.000 claims description 13
- 229960000458 allantoin Drugs 0.000 claims description 13
- 229920000370 gamma-poly(glutamate) polymer Polymers 0.000 claims description 13
- 239000011734 sodium Substances 0.000 claims description 13
- 229910052708 sodium Inorganic materials 0.000 claims description 13
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims description 12
- CLAHOZSYMRNIPY-UHFFFAOYSA-N 2-hydroxyethylurea Chemical compound NC(=O)NCCO CLAHOZSYMRNIPY-UHFFFAOYSA-N 0.000 claims description 12
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims description 12
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 claims description 12
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 12
- 241000187747 Streptomyces Species 0.000 claims description 12
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims description 12
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims description 12
- 229960003237 betaine Drugs 0.000 claims description 12
- 229940031575 hydroxyethyl urea Drugs 0.000 claims description 12
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 12
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 12
- 229930003427 Vitamin E Natural products 0.000 claims description 11
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 claims description 11
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 11
- 235000019165 vitamin E Nutrition 0.000 claims description 11
- 229940046009 vitamin E Drugs 0.000 claims description 11
- 239000011709 vitamin E Substances 0.000 claims description 11
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 9
- 229920002125 Sokalan® Polymers 0.000 claims description 9
- CBTVGIZVANVGBH-UHFFFAOYSA-N aminomethyl propanol Chemical compound CC(C)(N)CO CBTVGIZVANVGBH-UHFFFAOYSA-N 0.000 claims description 9
- 229960001631 carbomer Drugs 0.000 claims description 9
- QHGUCRYDKWKLMG-QMMMGPOBSA-N (R)-octopamine Chemical compound NC[C@H](O)C1=CC=C(O)C=C1 QHGUCRYDKWKLMG-QMMMGPOBSA-N 0.000 claims description 8
- QHGUCRYDKWKLMG-MRVPVSSYSA-N Octopamine Natural products NC[C@@H](O)C1=CC=C(O)C=C1 QHGUCRYDKWKLMG-MRVPVSSYSA-N 0.000 claims description 8
- 229960001576 octopamine Drugs 0.000 claims description 8
- 229940015975 1,2-hexanediol Drugs 0.000 claims description 7
- 241000609666 Tuber aestivum Species 0.000 claims description 7
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 6
- 238000001816 cooling Methods 0.000 claims description 6
- 229960005150 glycerol Drugs 0.000 claims description 6
- 238000010438 heat treatment Methods 0.000 claims description 6
- 239000004909 Moisturizer Substances 0.000 claims description 4
- DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 claims description 4
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims description 4
- 230000001333 moisturizer Effects 0.000 claims description 4
- 229940083542 sodium Drugs 0.000 claims description 4
- 230000001804 emulsifying effect Effects 0.000 claims description 3
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 2
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 2
- 230000002421 anti-septic effect Effects 0.000 claims description 2
- PXEDJBXQKAGXNJ-QTNFYWBSSA-L disodium L-glutamate Chemical compound [Na+].[Na+].[O-]C(=O)[C@@H](N)CCC([O-])=O PXEDJBXQKAGXNJ-QTNFYWBSSA-L 0.000 claims description 2
- ACCCMOQWYVYDOT-UHFFFAOYSA-N hexane-1,1-diol Chemical compound CCCCCC(O)O ACCCMOQWYVYDOT-UHFFFAOYSA-N 0.000 claims description 2
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 claims description 2
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 claims description 2
- 229960002216 methylparaben Drugs 0.000 claims description 2
- 235000013923 monosodium glutamate Nutrition 0.000 claims description 2
- UWJJYHHHVWZFEP-UHFFFAOYSA-N pentane-1,1-diol Chemical compound CCCCC(O)O UWJJYHHHVWZFEP-UHFFFAOYSA-N 0.000 claims description 2
- 229960005323 phenoxyethanol Drugs 0.000 claims description 2
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 claims description 2
- 229940073490 sodium glutamate Drugs 0.000 claims description 2
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 claims description 2
- 150000005846 sugar alcohols Polymers 0.000 claims description 2
- 239000000230 xanthan gum Substances 0.000 claims description 2
- 229920001285 xanthan gum Polymers 0.000 claims description 2
- 229940082509 xanthan gum Drugs 0.000 claims description 2
- 235000010493 xanthan gum Nutrition 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 27
- 239000006071 cream Substances 0.000 abstract description 10
- 210000003491 skin Anatomy 0.000 description 55
- 238000012360 testing method Methods 0.000 description 36
- 230000000052 comparative effect Effects 0.000 description 33
- 239000000523 sample Substances 0.000 description 7
- 230000002195 synergetic effect Effects 0.000 description 7
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 6
- 210000000245 forearm Anatomy 0.000 description 5
- 238000005259 measurement Methods 0.000 description 5
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 4
- 238000011160 research Methods 0.000 description 4
- 230000037394 skin elasticity Effects 0.000 description 4
- 229940088594 vitamin Drugs 0.000 description 4
- 229930003231 vitamin Natural products 0.000 description 4
- 235000013343 vitamin Nutrition 0.000 description 4
- 239000011782 vitamin Substances 0.000 description 4
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 239000004310 lactic acid Substances 0.000 description 3
- 235000014655 lactic acid Nutrition 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 102000008186 Collagen Human genes 0.000 description 2
- 108010035532 Collagen Proteins 0.000 description 2
- 102000016942 Elastin Human genes 0.000 description 2
- 108010014258 Elastin Proteins 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 240000007320 Pinus strobus Species 0.000 description 2
- 235000008578 Pinus strobus Nutrition 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 description 2
- 230000032683 aging Effects 0.000 description 2
- 229940024606 amino acid Drugs 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 229920001436 collagen Polymers 0.000 description 2
- 230000023753 dehiscence Effects 0.000 description 2
- 229920002549 elastin Polymers 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 210000002950 fibroblast Anatomy 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 229920002674 hyaluronan Polymers 0.000 description 2
- 229960003160 hyaluronic acid Drugs 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 150000003648 triterpenes Chemical class 0.000 description 2
- 230000037303 wrinkles Effects 0.000 description 2
- JSPNNZKWADNWHI-PNANGNLXSA-N (2r)-2-hydroxy-n-[(2s,3r,4e,8e)-3-hydroxy-9-methyl-1-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoctadeca-4,8-dien-2-yl]heptadecanamide Chemical compound CCCCCCCCCCCCCCC[C@@H](O)C(=O)N[C@H]([C@H](O)\C=C\CC\C=C(/C)CCCCCCCCC)CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O JSPNNZKWADNWHI-PNANGNLXSA-N 0.000 description 1
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 description 1
- 235000005638 Austrian pine Nutrition 0.000 description 1
- 239000002126 C01EB10 - Adenosine Substances 0.000 description 1
- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 241001107116 Castanospermum australe Species 0.000 description 1
- 229920001287 Chondroitin sulfate Polymers 0.000 description 1
- 102000029816 Collagenase Human genes 0.000 description 1
- 108060005980 Collagenase Proteins 0.000 description 1
- 241001260838 Cystoseira Species 0.000 description 1
- 235000018783 Dacrycarpus dacrydioides Nutrition 0.000 description 1
- 229920000045 Dermatan sulfate Polymers 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010013786 Dry skin Diseases 0.000 description 1
- 102000016359 Fibronectins Human genes 0.000 description 1
- 108010067306 Fibronectins Proteins 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 102000011782 Keratins Human genes 0.000 description 1
- 108010076876 Keratins Proteins 0.000 description 1
- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 235000008565 Pinus banksiana Nutrition 0.000 description 1
- 235000013264 Pinus jeffreyi Nutrition 0.000 description 1
- 235000014030 Podocarpus spicatus Nutrition 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 1
- 241000235347 Schizosaccharomyces pombe Species 0.000 description 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 1
- 206010040829 Skin discolouration Diseases 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 229960005305 adenosine Drugs 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 239000000043 antiallergic agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 235000021279 black bean Nutrition 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 229940106189 ceramide Drugs 0.000 description 1
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 description 1
- 229930183167 cerebroside Natural products 0.000 description 1
- RIZIAUKTHDLMQX-UHFFFAOYSA-N cerebroside D Natural products CCCCCCCCCCCCCCCCC(O)C(=O)NC(C(O)C=CCCC=C(C)CCCCCCCCC)COC1OC(CO)C(O)C(O)C1O RIZIAUKTHDLMQX-UHFFFAOYSA-N 0.000 description 1
- 229940059329 chondroitin sulfate Drugs 0.000 description 1
- 229960002424 collagenase Drugs 0.000 description 1
- 230000001143 conditioned effect Effects 0.000 description 1
- 238000013480 data collection Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 229940051593 dermatan sulfate Drugs 0.000 description 1
- AVJBPWGFOQAPRH-FWMKGIEWSA-L dermatan sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](C([O-])=O)O1 AVJBPWGFOQAPRH-FWMKGIEWSA-L 0.000 description 1
- 229910003460 diamond Inorganic materials 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- 239000003974 emollient agent Substances 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 239000003797 essential amino acid Substances 0.000 description 1
- 235000020776 essential amino acid Nutrition 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 230000000887 hydrating effect Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 230000036564 melanin content Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- VVGIYYKRAMHVLU-UHFFFAOYSA-N newbouldiamide Natural products CCCCCCCCCCCCCCCCCCCC(O)C(O)C(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC VVGIYYKRAMHVLU-UHFFFAOYSA-N 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 235000017985 rocky mountain lodgepole pine Nutrition 0.000 description 1
- 239000011669 selenium Substances 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 150000003408 sphingolipids Chemical class 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000037072 sun protection Effects 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 229940074410 trehalose Drugs 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/88—Polyamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9717—Rhodophycota or Rhodophyta [red algae], e.g. Porphyra
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cosmetics (AREA)
Abstract
本发明公开一种水润化妆水及其制备方法，涉及化妆品技术领域。本发明所述水润化妆水，包括以下组分：增稠剂、多元醇、保湿剂、pH调节剂、烟酰胺、凝血酸、皮肤调理剂和防腐剂；所述皮肤调理剂，包括以下组分：银耳提取物、奥婷敏、燕麦多肽、天女木兰提取物、黑松露提取物、白松露提取物、二裂酵母发酵产物溶胞物、欧囊链藻提取物、水溶性视黄醇、水解酵母蛋白和水解丝胶蛋白；其中，所述奥婷敏为水、乳酸杆菌/豆浆发酵产物滤液、丁二醇、1,2‑戊二醇的混合物。本发明的化妆水可以提高BB霜或气垫霜的滋润度、使得妆容更加顺滑，肌肤更加细腻水润。本发明的化妆水还可以单独使用，具有水润修护，提升肌肤水润度与光泽度。
Description
技术领域
本发明涉及化妆品技术领域，尤其是一种水润化妆水及其制备方法。
背景技术
近些年来消费者对美的追求越来越高，BB霜或气垫霜越来越受消费者的喜爱与追捧，其根本原因是BB霜或气垫霜使用方便具有隔离、防晒、粉底作用，可以帮助消费者打造完美的妆容，自信的出门。但是，使用这些产品的消费者很多都会出现卡粉，涂抹不够均匀，不够贴敷等等不良的体验。
发明内容
基于此，本发明的目的在于克服上述现有技术的不足之处而提供一种具有水润修护，提升肌肤水润度与光泽度的水润化妆水。
为实现上述目的，本发明所采取的技术方案为：一种水润化妆水，其特征在于，包括以下组分：增稠剂、多元醇、保湿剂、pH调节剂、烟酰胺、凝血酸、皮肤调理剂和防腐剂；所述皮肤调理剂，包括以下组分：银耳提取物、奥婷敏、燕麦多肽、天女木兰提取物、黑松露提取物、白松露提取物、二裂酵母发酵产物溶胞物、欧囊链藻提取物、水溶性视黄醇、水解酵母蛋白和水解丝胶蛋白；其中，所述奥婷敏为水、乳酸杆菌/豆浆发酵产物滤液、丁二醇、1,2-戊二醇的混合物。
本申请通过优选皮肤调理剂的组分，通过银耳提取物、奥婷敏、燕麦多肽、天女木兰提取物、黑松露提取物、白松露提取物、二裂酵母发酵产物溶胞物、欧囊链藻提取物、水溶性视黄醇、水解酵母蛋白和水解丝胶蛋白的配合使用，通过各种成分的相互配合，避免不同功效成分之间的抗拮作用充分发挥有效成分的作用，既能补水保湿，又能舒缓抗敏，全面的滋润肌肤，制备得到了一种具有水润修护，提升肌肤水润度与光泽度的水润化妆水。
奥婷敏是一种通过16种35株乳酸菌发酵获得的黑豆浆过滤液，所有的菌类都是在相同的培养基中培养，富含多种维生素和蛋白质，以及活性成分；因此，加入奥婷敏使化妆水具备了保湿、美白、杀菌和抗过敏的效果。
水解酵母蛋白的吸水吸湿能力、吸油能力、起泡性和助乳化能力略低。水溶液黏度略大，能迅速被皮肤吸收，无油腻感，适合用作化妆品的护肤原料。
燕麦多肽有强烈抑制蛋白酶活性，具有抗氧化的作用；同时还有助渗透的作用，帮助皮肤更好的吸收其他营养物质；同时赋予皮肤营养，调理肌肤，高效保湿，减少皮肤粗糙度。
银耳提取物对胶原蛋白酶活性的抑制，以及对若干生化成分生成的促进作用显示有活肤抗皱作用；提取物有很好的保湿作用；对皮肤的过敏也有一定的抑制作用，可用作舒缓抗敏剂。
二裂酵母发酵产物提取物蕴含氨基酸、维生素等营养，刺激细胞更新，延长细胞的寿命，还能促进伤口愈合和抗老化。
黑松露提取液是从黑松露中提取出来的，含有种类多样的蛋白质、18种氨基酸(包括人体不能合成的8种必需氨基酸)、不饱和脂肪酸、多种维生素、锌、锰、铁、钙、磷、硒等必需微量元素，以及鞘脂类、脑苷脂、神经酰胺、三萜、雄性酮、腺苷、松露酸、甾醇、松露多糖、松露多肽等大量的代谢产物；其中多糖、多肽、三萜具有增强免疫力、抗衰老、抗疲劳等作用。松露被誉为珍贵的“食中钻石”，它能帮助集中改善肌肤暗哑无华，淡化细纹，细腻匀称焕亮肌肤，还原肌肤光采。
优选地，所述皮肤调理剂，包括以下重量份的组分：银耳提取物0.03-0.3份、奥婷敏0.5-1.5份、燕麦多肽0.5-2份、天女木兰提取物0.05-0.5份、黑松露提取物0.1-1份、白松露提取物0.1-1份、二裂酵母发酵产物溶胞物0.1-0.5份、欧囊链藻提取物0.2-1份、水溶性视黄醇0.01-0.05份、水解酵母蛋白1-5份和水解丝胶蛋白0.3-1.5份。本申请发明人经过大量创造性试验研究发现，皮肤调理剂采用上述组分及重量份选择时，得到的化妆水的效果较好。
进一步优选地，所述皮肤调理剂，包括以下重量份的组分：银耳提取物0.05-0.2份、奥婷敏0.5-1.2份、燕麦多肽0.5-1.2份、天女木兰提取物0.05-0.3份、黑松露提取物0.1-0.5份、白松露提取物0.1-0.5份、二裂酵母发酵产物溶胞物0.1-0.3份、欧囊链藻提取物0.2-0.5份、水溶性视黄醇0.01-0.03份、水解酵母蛋白1-3份和水解丝胶蛋白0.3-1.0份。本申请发明人经过大量创造性试验研究发现，皮肤调理剂采用上述组分及重量份选择时，得到的化妆水的效果有明显的提高。
优选地，所述保湿剂，包括以下重量份的组分：透明质酸钠0.03-0.3份、尿囊素0.1-0.4份、甜菜碱0.5-1.5份、海藻糖0.3-1.5份、羟乙基尿素2-6份、聚谷氨酸钠0.05-0.5份和维生素E0.3-1.5份。
本申请通过优选保湿剂的组分，通过透明质酸钠、尿囊素、甜菜碱、海藻糖、羟乙基尿素、聚谷氨酸钠和维生素的配合使用，通过各种成分的相互配合，发挥其协同增效的效果。本申请制备得到了一种具有水润修护，提升肌肤水润度与光泽度的水润化妆水。
聚谷氨酸钠可提高皮肤里层的角质素(PCA)、乳酸(LA)及尿囊素(UCA)等含量，从而实现从皮肤内部增强其保湿能力。聚谷氨酸钠可刺激成纤维母细胞生长，还可以透过表皮层肌底。其中，成纤维母细胞参与多种细胞外机制成分分泌的过程，包括胶原蛋白、粘连蛋白、透明质酸、硫酸软骨素、硫酸皮肤素及弹性蛋白等的分泌调控。因此，聚谷氨酸钠增加了皮肤自身胶原蛋白、透明质酸及弹性蛋白等天然保湿、柔嫩因子的生成。
进一步优选地，所述保湿剂，包括以下重量份的组分：透明质酸钠0.05-0.2份、尿囊素0.15-0.3份、甜菜碱0.5-1.0份、海藻糖0.3-1份、羟乙基尿素2-5份、聚谷氨酸钠0.05-0.2份和维生素E0.5-1.2份。本申请发明人经过大量创造性试验研究发现，保湿剂采用上述组分及重量份选择时，得到的化妆水的效果有明显的提高。
优选地，所述增稠剂为卡波姆、黄原胶、聚丙烯酸钠中的至少一种；所述多元醇为甘油、丁二醇、丙二醇、二丙二醇、戊二醇中的至少一种；所述pH调节剂为氨甲基丙醇、氢氧化钠、三乙醇胺的至少一种；所述防腐剂为苯氧乙醇、对羟基苯乙酮、己二醇、羟苯甲酯中的至少一种。
此外，本申请提供了一种水润化妆水，包括以下重量份的组分：银耳提取物0.03-0.3份、奥婷敏0.5-1.5份、燕麦多肽0.5-2份、天女木兰提取物0.05-0.5份、黑松露提取物0.1-1份、白松露提取物0.1-1份、二裂酵母发酵产物溶胞物0.1-0.5份、欧囊链藻提取物0.2-1份、水溶性视黄醇0.01-0.05份、水解酵母蛋白1-5份、水解丝胶蛋白0.3-1.5份、透明质酸钠0.03-0.3份、尿囊素0.1-0.4份、甜菜碱0.5-1.5份、海藻糖0.3-1.5份、羟乙基尿素2-6份、聚谷氨酸钠0.05-0.5份、维生素E0.3-1.5份、卡波姆0.05-0.3份、甘油1.0-2.5份、丁二醇5-20份、二丙二醇1-7份、氨甲基丙醇0.03-0.15份、对羟基苯乙酮0.3-1.2份、烟酰胺1-5份、凝血酸1-3份、1，2-己二醇0.2-1.5份。
进一步地，本申请提供了一种水润化妆水，包括以下重量份的组分：银耳提取物0.05-0.2份、奥婷敏0.5-1.2份、燕麦多肽0.5-1.2份、天女木兰提取物0.05-0.3份、黑松露提取物0.1-0.5份、白松露提取物0.1-0.5份、二裂酵母发酵产物溶胞物0.1-0.3份、欧囊链藻提取物0.2-0.5份、水溶性视黄醇0.01-0.03份、水解酵母蛋白1-3份、水解丝胶蛋白0.3-1.0份、透明质酸钠0.05-0.2份、尿囊素0.15-0.3份、甜菜碱0.5-1.0份、海藻糖0.3-1份、羟乙基尿素2-5份、聚谷氨酸钠0.05-0.2份、维生素E 0.5-1.2份、卡波姆0.05-0.2份、甘油1.0-2份、丁二醇7-15份、二丙二醇2-5份、氨甲基丙醇0.03-0.1份、对羟基苯乙酮0.3-1.0份、烟酰胺1-3份、凝血酸1-2份、1，2-己二醇0.2-1.0份。
本申请还提供了所述的水润化妆水的制备方法，包括如下步骤：
(1)将水、卡波姆、透明质酸钠、聚谷氨酸钠、银耳提取物、尿囊素、甜菜碱、甘油、丁二醇加入到乳化锅中，加热搅拌至80-85度后均质3-5分钟，保温20分钟后降温至60-65度，得到混合物1；
(2)将对羟基苯乙酮加入到二丙二醇中，加热至60-65度并不断搅拌，得到混合物2，经混合物2加入步骤(1)中制备得到的混合物1，搅拌均匀且呈透明，得到混合物3；
(3)将用水预溶好的氨甲基丙醇加入到步骤(2)中制备得到的混合物3中，搅拌均匀透明，继续降温至40-45度，得到混合物4；
(4)将羟乙基尿素、燕麦多肽，水解丝胶蛋白、海藻糖、水解酵母蛋白、奥婷敏、黑松露提取物、白松露提取物、二裂酵母发酵产物溶胞产物、天女木兰提取物、水溶性视黄醇、维生素E、欧囊链藻提取物依次加入到步骤(3)中制备得到的混合物4中，搅拌均匀至呈透明状，得到混合物5；
(5)分别加入用水预溶好的烟酰胺和凝血酸到步骤(4)中制备得到的混合物5中，搅拌至透明均匀，得到混合物6；
(6)加入1，2己二醇到步骤(5)中制备得到的混合物6中，搅拌至透明均匀，得到所述水润化妆水。
相对于现有技术，本发明的有益效果为：本发明的化妆水可以配合BB霜或气垫霜一起使用，可以提高BB霜或气垫霜的滋润度、使得妆容更加顺滑，肌肤更加细腻水润。本发明的化妆水还可以单独使用，具有水润修护，提升肌肤水润度与光泽度。
具体实施方式
为更好的说明本发明的目的、技术方案和优点，下面将结合具体实施例对本发明作进一步说明。
本申请设置实施例1-5，具体实施例1-5的组分和重量份选择如表1所示，总重量份为100份：
表1实施例1-5的组分和重量份选择
本申请实施例所述水润化妆水的制备方法，包括如下步骤：
(1)将水、卡波姆、透明质酸钠、聚谷氨酸钠、银耳提取物、尿囊素、甜菜碱、甘油、丁二醇加入到乳化锅中，加热搅拌至80-85度后均质3-5分钟，保温20分钟后降温至60-65度，得到混合物1；
(2)将对羟基苯乙酮加入到二丙二醇中，加热至60-65度并不断搅拌，得到混合物2，经混合物2加入步骤(1)中制备得到的混合物1，搅拌均匀且呈透明，得到混合物3；
(3)将用水预溶好的氨甲基丙醇加入到步骤(2)中制备得到的混合物3中，搅拌均匀透明，继续降温至40-45度，得到混合物4；
(4)将羟乙基尿素、燕麦多肽，水解丝胶蛋白、海藻糖、水解酵母蛋白、奥婷敏、黑松露提取物、白松露提取物、二裂酵母发酵产物溶胞产物、天女木兰提取物、水溶性视黄醇、维生素E、欧囊链藻提取物依次加入到步骤(3)中制备得到的混合物4中，搅拌均匀至呈透明状，得到混合物5；
(5)分别加入用水预溶好的烟酰胺和凝血酸到步骤(4)中制备得到的混合物5中，搅拌至透明均匀，得到混合物6；
(6)加入1，2己二醇到步骤(5)中制备得到的混合物6中，搅拌至透明均匀，得到所述水润化妆水。
同时，本申请设置对比例，对比例1-9设置分别不含有一种或几种燕麦多肽、黑松露提取物、白松露提取物、二裂酵母发酵产物溶胞物，探究制备的化妆水的效果具体对比例设置如下表2所示；同时，本申请设置对比例10-14，探究制备的化妆水的效果，具体对比例设置如下表3所示；另外，本申请设置对比例15-19，探究制备的化妆水的效果，具体对比例设置如下表4所示，对比例除所列组分选择不同外，其余组分及重量份及制备方法与实施例5完全相同：
表2对比例1-9皮肤调理剂的组分和重量份选择
表3对比例10-14皮肤调理剂的组分和重量份选择
| 各组分 | 对比例10 | 对比例11 | 对比例12 | 对比例13 | 对比例14 |
| 银耳提取物 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 |
| 燕麦多肽 | 1 | 1 | 1 | 1 | 1 |
| 水解丝胶蛋白 | 0 | 0.8 | 0.8 | 0.8 | 0.8 |
| 水解酵母蛋白 | 2 | 0 | 2 | 2 | 2 |
| 奥婷敏 | 0.8 | 0.8 | 0 | 0.8 | 0.8 |
| 黑松露提取物 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 |
| 白松露提取物 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 |
| 二裂酵母发酵产物溶胞物 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 |
| 天女木兰提取物 | 0.25 | 0.25 | 0.25 | 0 | 0.25 |
| 水溶性视黄醇 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 |
| 欧囊链藻提取物 | 0.25 | 0.25 | 0.25 | 0.25 | 0 |
表4对比例15-19的保湿剂组分和重量份选择
效果例1保湿效果测试
对实施例1-5和对比例1-19的水润化妆水进行用皮肤测试仪的方法功效评估，用水分皮肤测试仪CK CM825水分测试探头测试。选择18-50岁的健康志愿者240名随机分为24组，选择前臂内侧作为测试区。
测试前准备：志愿者的受试部位前2-3天不能使用任何化妆品。测试前志愿者清洁双手前臂内测，然后在做好测量区域标记，并在温度20-25度，湿度45-65％的标准房间内静坐至少20min。
测试步骤：在志愿者的手臂内侧标记3cm*3cm试验区域，使用水分测试探头进行试验区域和对照区域测量皮肤的水分含量初始值。然后按(1.0±0.1)mg/cm2用量样品用量涂抹于测量区域内，测量4小时受试验区的皮肤水分含量，其结果如表5所示。
表5保湿效果测试结果
由表5可知，实施例1-5制备得到的水润化妆水的保湿效果达到最佳，实施例5效果最好；对比例1-19与实施例进行对比测试，研究发现，不管是缺少一种、两种还是多种皮肤调理剂或者保湿剂，对保湿效果都会产生很重大的影响。结果表明，本申请皮肤调理剂多种组分、以及保湿剂多种组分之间存在协同增效的保湿效果。
效果例2弹性功效测试
对实施例1-5和对比例1-9的水润化妆水进行用皮肤测试仪的方法功效评估，用多功能皮肤测试仪CK MPA580弹性测试探头测试。选择18-50岁的健康志愿者140名随机分为14组，选择前臂内侧作为测试区。
测试前准备：志愿者的受试部位前2-3天不能使用任何化妆品。测试前志愿者清洁双手前臂内测，然后在做好测量区域标记，并在温度20-25度，湿度45-65％的标准房间内静坐至少20min。
测试步骤：试用测试产品前对使用者然后按(1.0±0.1)mg/cm2用量样品用量涂抹于测量区域内，测量使用1个月后的皮肤弹性数值，其结果如表6所示。弹性数值越大，说明皮肤弹性越好。
表6弹性功效测试结果
| 初始值 | 1个月后测试值 | 变化值 | |
| 实施例1 | 0.36 | 0.52 | 0.16 |
| 实施例2 | 0.43 | 0.61 | 0.18 |
| 实施例3 | 0.45 | 0.65 | 0.2 |
| 实施例4 | 0.4 | 0.61 | 0.21 |
| 实施例5 | 0.44 | 0.76 | 0.32 |
| 对比例1 | 0.42 | 0.44 | 0.02 |
| 对比例2 | 0.34 | 0.39 | 0.05 |
| 对比例3 | 0.38 | 0.46 | 0.08 |
| 对比例4 | 0.35 | 0.42 | 0.07 |
| 对比例5 | 0.39 | 0.45 | 0.06 |
| 对比例6 | 0.37 | 0.49 | 0.12 |
| 对比例7 | 0.41 | 0.52 | 0.11 |
| 对比例8 | 0.43 | 0.53 | 0.1 |
| 对比例9 | 0.38 | 0.48 | 0.1 |
由表6可知，实施例1-5制备得到的水润化妆水的弹性效果达到最佳，实施例5效果最好；对比例1-9进行4种皮肤调理剂“燕麦多肽、黑松露提取物、白松露提取物、二裂酵母发酵产物溶胞物”的对比测试，分别缺少其中的一种或多种，申请人在试验研究过程中发现，皮肤调理剂的上述组分，不仅在保湿效果上有其协同增效的效果，且在淡化细纹、增加皮肤弹性的效果上也体现出显著的协同增效作用。
效果例3皮肤亮度测试
对实施例1-5和对比例1-14的水润化妆水进行用皮肤测试仪的方法功效评估，用皮肤色差探头及皮肤测试测试系统CL400、还有皮肤红黑色素测试仪及其测试探头Mexameter MX18。选择18-50岁的健康志愿者190名随机分为19组，选择脸部皮肤作为测试区。
测试前准备：志愿者的受试部位前2-3天不能使用任何化妆品。测试前志愿者清洁双手前臂内测，然后在做好测量区域标记，并在温度20-25度，湿度45-65％的标准房间内静坐至少20min。
测试步骤：试用测试产品前对试用者皮肤进行黑色素、色差数据的采集与测试，数据作为皮肤的初始值，连续使用4周。4周后在进行数据的采集与测试。黑色素MI值数值越高，说明皮肤中黑色素含量越高；亮度L值越大，颜色越偏向白色；反之，颜色越偏向黑色。
表7皮肤亮度测试结果
由表7可知，实施例1-5制备得到的水润化妆水的皮肤亮度效果达到最佳，实施例5效果最好；对比例1-9进行4种皮肤调理剂“燕麦多肽、黑松露提取物、白松露提取物、二裂酵母发酵产物溶胞物”的对比测试，分别缺少其中的一种或多种，申请人在试验研究过程中发现，皮肤调理剂的上述组分，不仅在保湿、淡化细纹、增加皮肤弹性的效果上有其协同增效的效果，且在保持皮肤亮度效果上也体现出显著的协同增效作用。并且，申请人研究发现，本申请化妆水中其它皮肤调理剂，在保持皮肤亮度效果上也体现出显著的协同增效作用，本申请皮肤调理剂为一个组合，想要达到本申请实施例提供的效果，必须在本申请多种组分的共同作用下才能得到。
最后所应当说明的是，以上实施例仅用以说明本发明的技术方案而非对本发明保护范围的限制，尽管参照较佳实施例对本发明作了详细说明，本领域的普通技术人员应当理解，可以对本发明的技术方案进行修改或者等同替换，而不脱离本发明技术方案的实质和范围。
Claims (9)
1.一种水润化妆水，其特征在于，包括以下组分：增稠剂、多元醇、保湿剂、pH调节剂、烟酰胺、凝血酸、皮肤调理剂和防腐剂；所述皮肤调理剂，包括以下组分：银耳提取物、奥婷敏、燕麦多肽、天女木兰提取物、黑松露提取物、白松露提取物、二裂酵母发酵产物溶胞物、欧囊链藻提取物、水溶性视黄醇、水解酵母蛋白和水解丝胶蛋白；其中，所述奥婷敏为水、乳酸杆菌/豆浆发酵产物滤液、丁二醇、1,2-戊二醇的混合物。
2.如权利要求1所述的水润化妆水，其特征在于，所述皮肤调理剂，包括以下重量份的组分：银耳提取物0.03-0.3份、奥婷敏0.5-1.5份、燕麦多肽0.5-2份、天女木兰提取物0.05-0.5份、黑松露提取物0.1-1份、白松露提取物0.1-1份、二裂酵母发酵产物溶胞物0.1-0.5份、欧囊链藻提取物0.2-1份、水溶性视黄醇0.01-0.05份、水解酵母蛋白1-5份和水解丝胶蛋白0.3-1.5份。
3.如权利要求1或2所述的水润化妆水，其特征在于，所述皮肤调理剂，包括以下重量份的组分：银耳提取物0.05-0.2份、奥婷敏0.5-1.2份、燕麦多肽0.5-1.2份、天女木兰提取物0.05-0.3份、黑松露提取物0.1-0.5份、白松露提取物0.1-0.5份、二裂酵母发酵产物溶胞物0.1-0.3份、欧囊链藻提取物0.2-0.5份、水溶性视黄醇0.01-0.03份、水解酵母蛋白1-3份和水解丝胶蛋白0.3-1.0份。
4.如权利要求1所述的水润化妆水，其特征在于，所述保湿剂，包括以下重量份的组分：透明质酸钠0.03-0.3份、尿囊素0.1-0.4份、甜菜碱0.5-1.5份、海藻糖0.3-1.5份、羟乙基尿素2-6份、聚谷氨酸钠0.05-0.5份和维生素E0.3-1.5份。
5.如权利要求1或4所述的水润化妆水，其特征在于，所述保湿剂，包括以下重量份的组分：透明质酸钠0.05-0.2份、尿囊素0.15-0.3份、甜菜碱0.5-1.0份、海藻糖0.3-1份、羟乙基尿素2-5份、聚谷氨酸钠0.05-0.2份和维生素E0.5-1.2份。
6.如权利要求1所述的水润化妆水，其特征在于，所述增稠剂为卡波姆、黄原胶、聚丙烯酸钠中的至少一种；所述多元醇为甘油、丁二醇、丙二醇、二丙二醇、戊二醇中的至少一种；所述pH调节剂为氨甲基丙醇、氢氧化钠、三乙醇胺的至少一种；所述防腐剂为苯氧乙醇、对羟基苯乙酮、己二醇、羟苯甲酯中的至少一种。
7.一种水润化妆水，其特征在于，包括以下重量份的组分：银耳提取物0.03-0.3份、奥婷敏0.5-1.5份、燕麦多肽0.5-2份、天女木兰提取物0.05-0.5份、黑松露提取物0.1-1份、白松露提取物0.1-1份、二裂酵母发酵产物溶胞物0.1-0.5份、欧囊链藻提取物0.2-1份、水溶性视黄醇0.01-0.05份、水解酵母蛋白1-5份、水解丝胶蛋白0.3-1.5份、透明质酸钠0.03-0.3份、尿囊素0.1-0.4份、甜菜碱0.5-1.5份、海藻糖0.3-1.5份、羟乙基尿素2-6份、聚谷氨酸钠0.05-0.5份、维生素E0.3-1.5份、卡波姆0.05-0.3份、甘油1.0-2.5份、丁二醇5-20份、二丙二醇1-7份、氨甲基丙醇0.03-0.15份、对羟基苯乙酮0.3-1.2份、烟酰胺1-5份、凝血酸1-3份、1，2-己二醇0.2-1.5份。
8.如权利要求7所述的水润化妆水，其特征在于，包括以下重量份的组分：银耳提取物0.05-0.2份、奥婷敏0.5-1.2份、燕麦多肽0.5-1.2份、天女木兰提取物0.05-0.3份、黑松露提取物0.1-0.5份、白松露提取物0.1-0.5份、二裂酵母发酵产物溶胞物0.1-0.3份、欧囊链藻提取物0.2-0.5份、水溶性视黄醇0.01-0.03份、水解酵母蛋白1-3份、水解丝胶蛋白0.3-1.0份、透明质酸钠0.05-0.2份、尿囊素0.15-0.3份、甜菜碱0.5-1.0份、海藻糖0.3-1份、羟乙基尿素2-5份、聚谷氨酸钠0.05-0.2份、维生素E 0.5-1.2份、卡波姆0.05-0.2份、甘油1.0-2份、丁二醇7-15份、二丙二醇2-5份、氨甲基丙醇0.03-0.1份、对羟基苯乙酮0.3-1.0份、烟酰胺1-3份、凝血酸1-2份、1，2-己二醇0.2-1.0份。
9.一种如权利要求7或8所述的水润化妆水的制备方法，其特征在于，包括如下步骤：
(1)将水、卡波姆、透明质酸钠、聚谷氨酸钠、银耳提取物、尿囊素、甜菜碱、甘油、丁二醇加入到乳化锅中，加热搅拌至80-85度后均质3-5分钟，保温20分钟后降温至60-65度，得到混合物1；
(2)将对羟基苯乙酮加入到二丙二醇中，加热至60-65度并不断搅拌，得到混合物2，经混合物2加入步骤(1)中制备得到的混合物1，搅拌均匀且呈透明，得到混合物3；
(3)将用水预溶好的氨甲基丙醇加入到步骤(2)中制备得到的混合物3中，搅拌均匀透明，继续降温至40-45度，得到混合物4；
(4)将羟乙基尿素、燕麦多肽，水解丝胶蛋白、海藻糖、水解酵母蛋白、奥婷敏、黑松露提取物、白松露提取物、二裂酵母发酵产物溶胞产物、天女木兰提取物、水溶性视黄醇、维生素E、欧囊链藻提取物依次加入到步骤(3)中制备得到的混合物4中，搅拌均匀至呈透明状，得到混合物5；
(5)分别加入用水预溶好的烟酰胺和凝血酸到步骤(4)中制备得到的混合物5中，搅拌至透明均匀，得到混合物6；
(6)加入1，2己二醇到步骤(5)中制备得到的混合物6中，搅拌至透明均匀，得到所述水润化妆水。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110674915.0A CN113318029A (zh) | 2021-06-17 | 2021-06-17 | 一种水润化妆水及其制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110674915.0A CN113318029A (zh) | 2021-06-17 | 2021-06-17 | 一种水润化妆水及其制备方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113318029A true CN113318029A (zh) | 2021-08-31 |
Family
ID=77423722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110674915.0A Pending CN113318029A (zh) | 2021-06-17 | 2021-06-17 | 一种水润化妆水及其制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113318029A (zh) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113456532A (zh) * | 2021-08-24 | 2021-10-01 | 广州莱倩化妆品有限公司 | 一种不含硅油的零毛孔妆前霜及其制备方法 |
| CN113786379A (zh) * | 2021-10-12 | 2021-12-14 | 广州市雅创化妆品有限公司 | 乳酸菌美白修护精华及其制备方法 |
| CN115054545A (zh) * | 2022-06-27 | 2022-09-16 | 广州汉方医学生物科技有限公司 | 一种含白松露菌提取物的护肤品及其制作工艺 |
| CN116617129A (zh) * | 2023-05-16 | 2023-08-22 | 广州天然国度生物科技有限公司 | 一种具有皮肤修复作用的组合物及一种护肤品 |
| CN116650370A (zh) * | 2023-06-19 | 2023-08-29 | 广州天然国度生物科技有限公司 | 一种皮肤延衰组合物及一种护肤品 |
| CN116672288A (zh) * | 2023-07-18 | 2023-09-01 | 广州天然国度生物科技有限公司 | 一种具有抗氧化功能的组合物及一种护肤品 |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107184486A (zh) * | 2017-07-06 | 2017-09-22 | 曾万祥 | 一种面膜液及含有该面膜液的面膜 |
| CN108272679A (zh) * | 2018-03-26 | 2018-07-13 | 广东盛美化妆品有限公司 | 一种含白玉兰提取物的亮肤美白化妆水及其制备方法 |
| CN108635252A (zh) * | 2018-06-11 | 2018-10-12 | 广东芭薇生物科技股份有限公司 | 一种乳化型化妆水及其制备方法 |
| CN110507594A (zh) * | 2019-09-17 | 2019-11-29 | 上海百雀羚生物科技有限公司 | 一种化妆水及其制备方法 |
| CN111374998A (zh) * | 2020-03-16 | 2020-07-07 | 中山市天图精细化工有限公司 | 一种睡眠喷雾组合物气雾剂及其制备方法 |
| CN111514074A (zh) * | 2020-06-03 | 2020-08-11 | 广州智尚生物科技有限公司 | 一种亮泽肌肤的组合物及其应用 |
| CN111821226A (zh) * | 2019-04-16 | 2020-10-27 | 广州尚凝化妆品科技有限公司 | 一种植物来源端粒酶组合物及其在化妆品中的新型应用 |
| CN112294734A (zh) * | 2020-11-02 | 2021-02-02 | 浙江英树生物科技有限公司 | 一种化妆水及其制备方法和生产设备 |
| CN112773732A (zh) * | 2021-03-11 | 2021-05-11 | 广州花出见生物科技有限公司 | 一种含蚕丝蛋白的滋润修复霜及其制备方法 |
-
2021
- 2021-06-17 CN CN202110674915.0A patent/CN113318029A/zh active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107184486A (zh) * | 2017-07-06 | 2017-09-22 | 曾万祥 | 一种面膜液及含有该面膜液的面膜 |
| CN108272679A (zh) * | 2018-03-26 | 2018-07-13 | 广东盛美化妆品有限公司 | 一种含白玉兰提取物的亮肤美白化妆水及其制备方法 |
| CN108635252A (zh) * | 2018-06-11 | 2018-10-12 | 广东芭薇生物科技股份有限公司 | 一种乳化型化妆水及其制备方法 |
| CN111821226A (zh) * | 2019-04-16 | 2020-10-27 | 广州尚凝化妆品科技有限公司 | 一种植物来源端粒酶组合物及其在化妆品中的新型应用 |
| CN110507594A (zh) * | 2019-09-17 | 2019-11-29 | 上海百雀羚生物科技有限公司 | 一种化妆水及其制备方法 |
| CN111374998A (zh) * | 2020-03-16 | 2020-07-07 | 中山市天图精细化工有限公司 | 一种睡眠喷雾组合物气雾剂及其制备方法 |
| CN111514074A (zh) * | 2020-06-03 | 2020-08-11 | 广州智尚生物科技有限公司 | 一种亮泽肌肤的组合物及其应用 |
| CN112294734A (zh) * | 2020-11-02 | 2021-02-02 | 浙江英树生物科技有限公司 | 一种化妆水及其制备方法和生产设备 |
| CN112773732A (zh) * | 2021-03-11 | 2021-05-11 | 广州花出见生物科技有限公司 | 一种含蚕丝蛋白的滋润修复霜及其制备方法 |
Non-Patent Citations (1)
| Title |
|---|
| 国产非特殊用途化妆品备案服务平台: "FAITHPITT凡碧诗奢润滢亮精华液", 《国产普通化妆品备案信息》 * |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113456532A (zh) * | 2021-08-24 | 2021-10-01 | 广州莱倩化妆品有限公司 | 一种不含硅油的零毛孔妆前霜及其制备方法 |
| CN113786379A (zh) * | 2021-10-12 | 2021-12-14 | 广州市雅创化妆品有限公司 | 乳酸菌美白修护精华及其制备方法 |
| CN115054545A (zh) * | 2022-06-27 | 2022-09-16 | 广州汉方医学生物科技有限公司 | 一种含白松露菌提取物的护肤品及其制作工艺 |
| CN115054545B (zh) * | 2022-06-27 | 2023-03-03 | 广州汉方医学生物科技有限公司 | 一种含白松露菌提取物的护肤品制作工艺 |
| CN116617129A (zh) * | 2023-05-16 | 2023-08-22 | 广州天然国度生物科技有限公司 | 一种具有皮肤修复作用的组合物及一种护肤品 |
| CN116617129B (zh) * | 2023-05-16 | 2024-09-03 | 广州天然国度生物科技有限公司 | 一种具有皮肤修复作用的组合物及一种护肤品 |
| CN116650370A (zh) * | 2023-06-19 | 2023-08-29 | 广州天然国度生物科技有限公司 | 一种皮肤延衰组合物及一种护肤品 |
| CN116672288A (zh) * | 2023-07-18 | 2023-09-01 | 广州天然国度生物科技有限公司 | 一种具有抗氧化功能的组合物及一种护肤品 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN113318029A (zh) | 一种水润化妆水及其制备方法 | |
| JP4099173B2 (ja) | コンブチャ（ｋｏｍｂｕｃｈａ）を含む化粧品または皮膚用薬組成物 | |
| CN111214427B (zh) | 一种无酸焕肤组合物及制备方法和含该组合物的精华液 | |
| CN113230196B (zh) | 一种抗衰修护精华液及其制备方法 | |
| CN110025528A (zh) | 一种不含去离子水的抗氧化美白精华液及其制备方法 | |
| CN110592151A (zh) | 乳酸菌生产高含γ-氨基丁酸发酵液及其在化妆品中的应用 | |
| CN113786379A (zh) | 乳酸菌美白修护精华及其制备方法 | |
| CN112402358B (zh) | 一种具有防脱发功能的益生菌植物发酵产品及制备方法 | |
| CN108030721A (zh) | 一种精华液及其制备方法 | |
| CN110496067A (zh) | 一种祛皱组合物及其制备方法和应用 | |
| CN113456569A (zh) | 一种皮肤弹性修复补水面膜及其制备方法 | |
| KR20110130820A (ko) | 천년초 선인장 발효조성물을 주성분으로 하는 한방 화장품 제조방법 | |
| CN110917109A (zh) | 一种抗衰老面膜 | |
| CN113499305A (zh) | 一种植物源补水保湿面膜及其制备方法 | |
| CN112773761B (zh) | 一种化妆品组合物、精华液及其制备方法 | |
| TWI701033B (zh) | 膠原纖維的集束能增強劑 | |
| CN105310972A (zh) | 一种抗皱护肤品 | |
| CN108324587A (zh) | 一种抗老除皱组合物 | |
| CN109077971B (zh) | 一种发酵豆乳的制备方法及其在化妆品中的应用 | |
| CN110448518A (zh) | 一种美白身体乳的制备方法 | |
| CN112972361B (zh) | 一种组合物及其制备方法和抗老化化妆品 | |
| CN113730289B (zh) | 一种具有多重修护功效的眼唇护理组合物及其应用 | |
| CN116077386A (zh) | 一种具有修护功效的乳液及其制备方法 | |
| CN108653146A (zh) | 一种营养护手霜的制作方法 | |
| CN109908036A (zh) | 一种去屑止痒的头皮精油及其制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210831 |