CN113304181A - 一种治疗风湿、类风湿、痛风的中药组合物 - Google Patents
一种治疗风湿、类风湿、痛风的中药组合物 Download PDFInfo
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Abstract
本发明公开了一种治疗风湿、类风湿关节炎和痛风的中药组合物，由红花、槲寄生、川穹、当归、过岗龙、两面针按一定重量配比制备而成。本发明的药物主治急性风湿性关节炎、一般风湿性关节炎、移动性风湿关节炎、类风湿性关节炎。本发明采用皮下注射，外敷，烤电相结合，效果更为显著。
Description
技术领域
本发明属于中药技术领域，尤其是涉及一种治疗风湿、类风湿、痛风的中药。
背景技术
风湿、类风湿沿海、草原、内地痛风发病率越来越高，并呈现年轻化状态，全国权威统计痛风患者一亿人，并呈严重上升趋势，是继三高之后的第四高。
风湿性关节炎属变态反应性疾病，是风湿热的主要表现之一，多以急性发热及关节疼痛起病，典型表现是轻度或中度发热，游走性多关节炎，受累关节多为膝，踝、肩、肘，腕等大关节，常见由一个关节转移至另一个关节，病变局部呈现红，肿、灼热、剧痛，部分病人也有几个关节同时发病，不典型的病人仅有关节疼痛而无其他炎症表现，急性炎症一般于2-4周消退，不留后遗症，但常反复发作。若风湿活动影响心脏，则可发生心肌炎，甚至遗留心脏瓣膜病变。
类风湿关节炎是一种以慢性进行性关节病变为主的自身免疫性疾病，对称性的多关节炎，以双手、腕、肘、膝、踝和足关节受累最常见。同时患者可伴有发热、贫血、皮下结节、血管炎、心包炎及淋巴结肿大等关节外表现，血清中可有多种自身抗体，未经正确治疗的类风湿关节炎可反复的发作，迁延多年，最终导致晚期手指、碗、肘、膝、踝等关节变形及功能丧失，手X线片见骨质疏松、关节面破坏及关节腔狭窄。
痛风患者关节部位出现严重的水肿，炎症，疼痛感将持续几天甚至数周。
发明内容
针对现有技术中存在的西医副作用大，而中医见效慢，治疗周期长的问题，本发明提供一种快速高效的中医皮下渗透药液。
一种治疗风湿、类风湿、痛风中药组合物，由以下重量份的原料药组成：红花 30-60份、槲寄生30-60份、川穹30-60份、当归30-60份。
其中，所述的中药组合物还含有过岗龙30-60份，两面针30-60份。
其中，所述的中药组合物具体为当归50g 川穹50g 过岗龙50g 两面针50g 槲寄生50g 红花59g。
一种由上述中药组合物制备的中药制剂，中药制剂包括口服液、外敷液、膏药和中药皮下渗透药液。
其中，所述的制剂形式为中药皮下渗透药液。
其中，所述的中药皮下渗透药液，制备方法含有以下步骤：
1）取当归、川穹、过岗龙、两面针、槲寄生五味加水煎煮两次，第一次2小时，第二次1.5小时，合并煎液滤过，滤液减压浓缩、放冷，经水提醇沉后活性炭处理，滤过，加3倍量水，充分搅拌，冷藏48小时，滤过、减压，药液备用；
2）红花加水煎煮两次，每次1小时，合并煎液，滤过、减压、放冷，经水提醇沉，活性炭处理放冷，静置过夜，重复一次后加3倍水充分搅拌，冷藏48小时，滤过减压，药液备用；
3）将步骤1）和2）的备用药液合并，加2倍体积水，充分搅拌，冷藏24小时滤过。
4）将步骤3）得到的滤液加表面活性剂，并加1000ml水搅匀，20%氢氧化钠调节PH值5.6至7.0滤过，灌封灭菌既得。
其中，所述的表面活性剂为山梨酸80或吐温80。
其中，所述的制剂采用皮下注射方法，即直接进行皮下注射。
皮下渗透是将现代科学给药技术与传统中医相结合，采用注射或电针疗法，将中医组方制备的皮下渗透药液导入病灶区，立竿见影。
槲寄生具有祛风湿，强筋骨，能缓解关节疼痛，麻木，屈伸不力，等症状为君药。
当归，补血活血，通经止痛，川芎具有活血化瘀，行气，祛风止痛，辅助君药增强疗伤止痛之效，为臣药。
穿山龙，既能祛风除湿，舒筋活络，又有活血止痛的作用，
红花，具有活血通经，祛瘀止痛的作用共为佐药。
诸药合用，共奏活血散瘀，祛风除湿，消肿止痛之功效！
本发明有益效果
本发明采用纯天然中药，制备得到中药皮下渗透药液，改变传统中医的给药方式，根据病人病灶情况，将药物直接导入病灶处，通过经络皮下用药，快速分散走局部血尿酸及结晶，使患处血尿酸成为正常值，疼痛症状快速消失。
具体实施方式
以下实施例为本诊所就诊的病患实施例，在诊断过程中，由于个体病情差异，根据需要在原组方上进行适当的调整。
实施例1
姚XX，女，58岁，
2020.5.8就诊，病人自述，自五年前，前腿部疼痛，发沉，僵硬，腹部活动受限。检查腰3/4，4/5椎两侧有压痛。诊断为腰3/4，4/5椎间盘突出，压迫神经导致。采用皮下用药，腰椎推拿复位。配槲寄生 10g，两面针 10g，红花10g，当归40g，川穹40g，穿山龙40g，药液皮下注射，药渣外敷
2020.5.20 前腿部疼痛明显缓解，腹部可活动，腰3/4，4/5椎两侧压痛感消失，腿部不在僵硬。改组方两面针6g，当归10g，穿山龙6g，槲寄生6g，皮下用药皮配合药渣外敷，巩固疗效。
实施例2
岳XX，男，52岁，
2018.7.11就诊，病人自述使用海鲜稍许，有痛风发作。右脚不能行走，踝关节红肿。配两面针10g，槲寄生12g，当归14g，川穹10g，穿山龙10g，红花6g，并额外采用威灵仙10g，木瓜12g。共配五服，每日一剂，皮下注射和烤电治疗。
2018.7.20经过前期治疗，已能行走，红肿减轻，后续重要口服，药渣外敷，巩固治疗。
2018.7.25 患者已基本痊愈，注意劳逸结合，少吃海鲜。
实施例3
黄XX，女，37岁，
2019.6.1就诊，病人自述腰疼2年，右侧疼痛明显，受凉疼痛加重。
检查，腰椎右侧压痛明显，CT，腰椎4/5 5/5突出。诊断，腰椎间盘突出。治疗：皮下用药，腰椎整复，烤电。配槲寄生10g，两面针10g，红花6g，当归10g，当归6g，穿山龙10g。五服，药渣外敷。
2019.6.2 治疗一次，症状短暂消失。
2019.6.10 症状减轻。
2019.6.13 经治疗，疼痛有所缓解，活动自如，症状基本消失。
Claims (7)
1.一种治疗风湿、类风湿、痛风的中药组合物，其特征在于，由以下重量份的原料药组成：红花30-60份、槲寄生30-60份、川穹30-60份、当归30-60份。
2.根据权利要求1所述的中药组合物，其特征在于，所述的中药组合物还含有过岗龙30-60份，两面针30-60份。
3.根据权利要求2所述的中药组合物，其特征在于，所述的中药组合物具体为当归50g川穹50g 过岗龙50g 两面针50g 槲寄生50g 红花59g。
4.一种由权利要求1-3任一所述的中药组合物制备的中药制剂，其特征在于，中药制剂包括口服液、外敷液、膏药和中药皮下渗透药液。
5.根据权利要求4所述的中药制剂，其特征在于，所述的制剂形式为中药皮下渗透药液。
6.根据权利要求4或5任一所述的中药制剂，其特征在于，所述的中药皮下渗透药液，制备方法含有以下步骤：
1）取当归、川穹、过岗龙、两面针、槲寄生五味加水煎煮两次，第一次2小时，第二次1.5小时，合并煎液滤过，滤液减压浓缩、放冷，经水提醇沉后活性炭处理，滤过，加3倍量水，充分搅拌，冷藏48小时，滤过、减压，药液备用；
2）红花加水煎煮两次，每次1小时，合并煎液，滤过、减压、放冷，经水提醇沉，活性炭处理放冷，静置过夜，重复一次后加3倍水充分搅拌，冷藏48小时，滤过减压，药液备用；
3）将步骤1）和2）的备用药液合并，加2倍体积水，充分搅拌，冷藏24小时滤过；
4）将步骤3）得到的滤液加表面活性剂，并加1000ml水搅匀，20%氢氧化钠调节PH值5.6至7.0滤过，灌封灭菌既得。
7.根据权利要求6所述的中药制剂，其特征在于，所述的表面活性剂为山梨酸80或吐温80。
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