CN1132624A - Medicatedbath lotion and its prepn - Google Patents
Medicatedbath lotion and its prepn Download PDFInfo
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- CN1132624A CN1132624A CN 95107554 CN95107554A CN1132624A CN 1132624 A CN1132624 A CN 1132624A CN 95107554 CN95107554 CN 95107554 CN 95107554 A CN95107554 A CN 95107554A CN 1132624 A CN1132624 A CN 1132624A
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- medicatedbath lotion
- medicatedbath
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Abstract
A medicinal bath lotion serving to clean, increase the excretory and absorptive functions of skin and raise the skin-penetrating function of medicine by at least 4 times is prepared by steaming or decocting Chinese-medicinal components, removing dregs and taking clear liquid, heating distilled water to 60-70 deg.C, stirring while adding surfactant until full dissolution, mixing with Chinese-medicinal clear liquid, and stirring. Excipient, pH regulator and skin penetrating agent are optional.
Description
The present invention relates to a kind of having a bath and use preparation, particularly a kind of Medicatedbath lotion and preparation method thereof.
Medicinal bath therapy is the important component part of external treatment of Chinese medicine.It utilizes the clear liquid of prescription Chinese medicine gained after decoction is removed slag to be used to soak bathing, reaches the purpose of preventing and treating diseases.There is the following points weak point in actual use in this aqueous clear liquid that does not contain other additive: the decontamination detergent power is poor, owing to can't remove the dirt that stops up hair follicle hole, sweat pore and adipose gland hole, thereby hindered drug absorption, made medicament be difficult to bring into play due effect; Hydration to skin is poor, and medicine is difficult to by the hair follicle approach with skin permeation; The transdermal insufficiency of function can not make the property of medicine go into its space between skin and muscles from pore well, stimulates the menstrual flow and passes through network to reach ideal effect.
The objective of the invention is to overcome weak point of the prior art and provide a kind of decontamination detergent power strong, strong to the hydration of skin, Medicatedbath lotion of transdermal better function and preparation method thereof.
The objective of the invention is to realize by following approach.
Medicatedbath lotion is made up of through the decoction gained clear liquid face that removes slag prescription Chinese medicine, also contains the surfactant that accounts for Medicatedbath lotion gross weight 15-45% in the said Medicatedbath lotion.
Surfactant not only can emulsifying be removed obstruction hair follicle hole, the dirt in sweat pore and adipose gland hole, and the passage that unobstructed human body skin absorbs the drug, and also it also can promote the penetrance of medicine to the epidermis lipid membrane.
Purpose of the present invention can also reach by following measure.
Also contain in the said Medicatedbath lotion and account for its gross weight 1-5% excipient.
Excipient has moisture-keeping functions, can be lastingly because of the remollescent horny layer of hydration, thus promote the skin absorbs property of medicine.And; when we use excipient and surfactant common combination together; not only kept the two original effect; but also produced another kind of effect; can promote effectively that medicine passes through the infiltration of hair follicle approach, the skin moisture-keeping factor (NMF) that protection is made up of its acid of ammonia and low molecular protein helps the absorption of human body to medicine.
The said surfactant person of one-tenth is made up of non-ionic surface active agent, perhaps is made up of zwitterionic surfactant.Perhaps combine and form by anion surfactant and zwitterionic surfactant.
Said surfactant is accounted for anion surfactant, the zwitterionic surfactant of 7-45% and the non-ionic surface active agent of the 9-70% composition of its 20-85% respectively by weight.
Said excipient or propylene glycol or glycerol.
Concrete selection for excipient is multiple, can be higher alcohol, also can be glycerol, can also be glycerol, preferably propylene glycol.
Contain the PH regulator that accounts for Medicatedbath lotion gross weight 0.2～3% of Medicatedbath lotion P value being adjusted to PH5-6 in the said Medicatedbath lotion.
Like this, make hydrophilic matrix pH value in the Medicatedbath lotion be with human body skin mutually and faintly acid, thereby, water is fully spread at subcuticle, horny layer is expandable into cellular through this hydration, experiment shows, when the cuticlar water tissue gathers when being increased to 50% from 5-15%, its permeability can increase 4-5 doubly.
Said PH regulator or undecylenic acid, or lactic acid, perhaps salicylic acid, or boric acid uses citric acid usually.
Also contain the transdermal agent that accounts for its gross weight 0.2-5% in the said Medicatedbath lotion.
This transdermal agent or nitroglycerin or dimethyl sulfoxide, but azone preferably.
The Medicatedbath lotion preparation method, dipping is removed slag with the steaming and decocting of prescription Chinese medicine, collect clear liquid, distilled water is added in the pot, be heated to 60-70 ℃, under agitation add the surfactant that accounts for Medicatedbath lotion gross weight 15-45%, fully after the dissolving, mix with the Chinese medicine clear liquid, and stir, obtain solution A and be Medicatedbath lotion.
The excipient that accounts for Medicatedbath lotion gross weight 3-5% is dropped into stirring at least 5 public clocks in the solution A.
Above-described preparation method preferably further is specially: with said excipient with account for the ethanol that the Medicatedbath lotion gross weight is respectively 1-5%, the transdermal agent of 0.5-5% device in addition mixes, dissolving, after stirring, add the PH regulator and the solution A that account for Medicatedbath lotion gross weight 1-3% and continue to stir 20 public clocks, leave standstill at least 5 hours after-filtration of ageing.
In sum, Medicatedbath lotion of the present invention and preparation method thereof has following advantage compared to existing technology: take out stains, improve skin and drain and absorption function; Hydration to skin is strong, the horny layer water content that fully expands is rolled up, thereby being the medicine penetrance increases more than 4-5 times, the combined effect of multiple auxiliary agent, effectively promoted the infiltration of medicine by the hair follicle approach, so transdermal better function, making the medicinal ingredient in the Medicatedbath lotion is thereby that abundant absorption of human body institute strengthened rapid, the direct characteristics of medicinal bath therapy effect greatly, and this Medicatedbath lotion preparation method of the present invention is simple and easy to do, equipment needed thereby is few, is convenient to the large-scale industrialization class and produces.
Below our knot can carry out more detailed description to the present invention by embodiment.
Embodiment 1
The percentage ratio that Medicatedbath lotion, its prescription and each component account for the Medicatedbath lotion gross weight is:
Anion surfactant 27% (wherein aliphatic alcohol polyethenoxy acid sulphuric acid diethanolamine salt 8%, sodium lauryl sulphate 1.5%, fatty alcohol-polyoxyethylene ether amber acid ester sulfonate 17.5%)
Zwitterionic surfactant (coconut monoethanolamide base CAB) 7%
Non-ionic surface active agent (Cortex cocois radicis fat alkanolamide) 3%
Transdermal agent (Laurel nitrogen single ketones) 1%
Excipient (propylene glycol) 3%
PH regulator (citric acid) 0.3%
Antiseptic (triumphant loose CG) 0.05%
Essence 0.20%
Solvent (ethanol) 1.5%
All the other are the Chinese medicine clear liquid.
Prescriptions of Chinese medicine in the present embodiment is:
Very light blue 3 of Folium Perillae 50 gram Radix Saposhnikoviaes 30 gram Herba Schizonepetae 30 grams
The Rhizoma Zingiberis Recens 25 gram Herba Pogostemoniss 30 gram Radixs Angelicae Dahuricae 20 grams
The Medicatedbath lotion preparation method in case the prescription Chinese medicine of flu is cleaned with cold water, adds water to above-mentioned usefulness above medical surfaces 3-5 centimetre, with after soaking, places vessel to decoct twice when kind was above in 20 minutes, the gained decoction is filtered through the sucking filtration machine draw clear liquid; Distilled water is added in the pot, be heated to 60-70 ℃ and under agitation add anion surfactant, zwitterionic surfactant, non-ionic surface active agent respectively, behind the mixing, add the Chinese medicine clear liquid, obtain solution A, with ethanol and excipient, antiseptic, transdermal agent in addition device mixes, after dissolving is even, mix with solution A, after stirring, add the PH regulator, the Medicatedbath lotion pH value is adjusted to PH5-6, can after cooling, add natural essence for increasing sense organ atmosphere.After all prescription raw materials all add, continue to stir 30 minutes, by homogenizer, obtain more even more stable product then, leave standstill, the ageing 6-10 hour canned finished product that is of last filtration.
It is same as the prior art that present embodiment is not stated part.
Embodiment 2:
Prescription Chinese medicine is had a headache for control, and its prescription is as follows:
Folium Mori 4.5 gram Radix Saposhnikoviaes 4.5 gram Herba Menthaes 3 gram Rhizoma Gastrodiaes 3 grams
Blue or green Fructus Forsythiae 4.5 gram Flos Lonicerae 3 gram Gypsum Fibrosum 10 gram Fructus Zanthoxylis 2 grams
It is identical with embodiment 1 that present embodiment is not stated part.
Embodiment 3:
Prescription Chinese medicine is treatment rheumatic arthritis, and its prescription is as follows:
Herba speranskiae tuberculatae 50 gram Flos Carthamis 25 gram Radix Aconitis 20 gram Radix Aconiti Kusnezoffii 20 grams
Caulis Spatholobi 30 gram Ramulus Cinnamomi 20 gram Radix Clematidis 20 grams
It is identical with embodiment 1 that present embodiment is not stated part.
Embodiment 4
Prescription Chinese medicine is the treatment skin pruritus, and its prescription is as follows:
Herba Xanthii grass 50 gram Folium Artemisiae Argyis 50 gram Nidus Vespae 30 gram Cortex Dictamnis 30 grams
The Radix Sophorae Flavescentis 30 gram Fructus Kochiae 30 gram Fructus Toosendan skins 30 gram Fructus Zanthoxylis 20 grams
It is identical with embodiment 1 that Alumen 20 gram present embodiments are not stated part.
Property embodiment:
Prescription Chinese medicine is the fat-reducing prescription: it is identical with embodiment 1 that the Flos Genkwa 10 gram Folium Nelumbinis 15 gram Radix Stephaniae Tetrandrae 15 gram Radixs Astragali 30 gram Herba Leonuris 15 gram Radix Rhapontici 30 gram Semen Gleditsiae 10 gram Concha Haliotidis 15 gram Semen Cassiae 15 gram Exocarpium Benincasaes 30 gram Cortex Sclerotii Poriae 30 gram Cortex Acanthopanciss 20 gram Folium Citri tangerinae 10 gram present embodiments are not stated part.
Claims (12)
1. Medicatedbath lotion is removed slag the gained clear liquid and forms through decoction by prescription Chinese medicine, it is characterized in that, also contains the surfactant that accounts for Medicatedbath lotion gross weight 15-45% in the said Medicatedbath lotion.
2. according to the said Medicatedbath lotion of claim 1, it is characterized in that, also contain in the said Medicatedbath lotion and account for its gross weight 1-5% excipient.
3. according to the said Medicatedbath lotion of claim 1, it is characterized in that, said surfactant or be made up of non-ionic surface active agent perhaps is made up of zwitterionic surfactant, is perhaps combined by anion surfactant and zwitterionic surfactant and forms.
4. according to the said Medicatedbath lotion of claim 3, it is characterized in that said surfactant is accounted for anion surfactant, the zwitterionic surfactant of 7-45% and the non-ionic surface active agent of the 9-70% composition of its 20-85% respectively by weight.
5. according to the said Medicatedbath lotion of claim 2, it is characterized in that said excipient or propylene glycol or glycerol.
6. according to the said Medicatedbath lotion of claim 1, it is characterized in that, also contain the PH regulator that accounts for Medicatedbath lotion gross weight 0.2-3% of the Medicatedbath lotion pH value being adjusted to PH5-6 in the said Medicatedbath lotion.
7. according to the said Medicatedbath lotion of claim 6, it is characterized in that said PH regulator or undecylenic acid, or lactic acid, or salicylic acid, or boric acid use citric acid usually.
8. according to the said Medicatedbath lotion of claim 1, it is characterized in that, also contain the transdermal agent that accounts for its gross weight 0.2-5% in the said Medicatedbath lotion.
9. the said dipping of claim 8 is characterized in that, said transdermal agent or nitroglycerin, or dimethyl sulfoxide, preferably azone.
10. Medicatedbath lotion preparation method, dipping is removed slag with the prescription decocting for Chinese herbal medicine, draw clear liquid, it is characterized in that, distilled water is added in the pot, be heated to 60-70 ℃, under agitation add the surfactant that accounts for Medicatedbath lotion gross weight 15-45%, fully after the dissolving, mix with the Chinese medicine clear liquid, and stir, obtain solution A.
11. according to the said Medicatedbath lotion preparation method of claim 10, it is characterized in that, the excipient that accounts for Medicatedbath lotion gross weight 3-5% dropped into stir at least 5 public clocks in the solution A.
12. Medicatedbath lotion preparation method according to claim 11, it is characterized in that, with said excipient with account for the ethanol that the Medicatedbath lotion gross weight is respectively 1-5%, the transdermal agent of 0.5-5% device in addition mixes, dissolving after stirring, adds the PH regulator and the solution A that account for Medicatedbath lotion gross weight 1-3% and continues to stir 20 public clocks, leave standstill at least 5 hours after-filtration of ageing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 95107554 CN1132624A (en) | 1995-07-10 | 1995-07-10 | Medicatedbath lotion and its prepn |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 95107554 CN1132624A (en) | 1995-07-10 | 1995-07-10 | Medicatedbath lotion and its prepn |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1132624A true CN1132624A (en) | 1996-10-09 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 95107554 Pending CN1132624A (en) | 1995-07-10 | 1995-07-10 | Medicatedbath lotion and its prepn |
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| CN (1) | CN1132624A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103110868A (en) * | 2013-01-08 | 2013-05-22 | 于艳丽 | Skin care solution and preparation method thereof |
| CN103638490A (en) * | 2013-12-05 | 2014-03-19 | 青岛友铭辰生物技术有限公司 | Chinese medicinal lotion for treating dandruff and preparation method thereof |
| CN105168661A (en) * | 2015-10-12 | 2015-12-23 | 临沂草之美医药科技有限公司 | Traditional Chinese medicine liniment for treating skin itch and preparation method thereof |
| CN105381298A (en) * | 2015-12-10 | 2016-03-09 | 佛山市朗达信息科技有限公司 | Bath teabag with weight reducing efficacy |
| CN109106916A (en) * | 2018-10-31 | 2019-01-01 | 成都体育学院 | A kind of Chinese medicine composition and preparation method thereof for treating rheumatic arthritis |
| CN109248225A (en) * | 2017-07-13 | 2019-01-22 | 宁夏伊康回族医药研究所（有限公司） | Heumatism medicine xiaolingxian dissipates |
| CN115887544A (en) * | 2022-12-07 | 2023-04-04 | 内蒙古赫缘生物科技有限公司 | Water-soluble silicon traditional Chinese medicine bath |
-
1995
- 1995-07-10 CN CN 95107554 patent/CN1132624A/en active Pending
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103110868A (en) * | 2013-01-08 | 2013-05-22 | 于艳丽 | Skin care solution and preparation method thereof |
| CN103110868B (en) * | 2013-01-08 | 2014-06-25 | 于艳丽 | Skin care solution and preparation method thereof |
| CN103638490A (en) * | 2013-12-05 | 2014-03-19 | 青岛友铭辰生物技术有限公司 | Chinese medicinal lotion for treating dandruff and preparation method thereof |
| CN105168661A (en) * | 2015-10-12 | 2015-12-23 | 临沂草之美医药科技有限公司 | Traditional Chinese medicine liniment for treating skin itch and preparation method thereof |
| CN105381298A (en) * | 2015-12-10 | 2016-03-09 | 佛山市朗达信息科技有限公司 | Bath teabag with weight reducing efficacy |
| CN109248225A (en) * | 2017-07-13 | 2019-01-22 | 宁夏伊康回族医药研究所（有限公司） | Heumatism medicine xiaolingxian dissipates |
| CN109106916A (en) * | 2018-10-31 | 2019-01-01 | 成都体育学院 | A kind of Chinese medicine composition and preparation method thereof for treating rheumatic arthritis |
| CN109106916B (en) * | 2018-10-31 | 2021-06-11 | 成都体育学院 | A Chinese medicinal composition for treating rheumatic arthritis, and preparation method thereof |
| CN115887544A (en) * | 2022-12-07 | 2023-04-04 | 内蒙古赫缘生物科技有限公司 | Water-soluble silicon traditional Chinese medicine bath |
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