CN113197227A - Bactericide for toothbrush sterilizing box - Google Patents

Bactericide for toothbrush sterilizing box Download PDF

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Publication number
CN113197227A
CN113197227A CN202110314492.1A CN202110314492A CN113197227A CN 113197227 A CN113197227 A CN 113197227A CN 202110314492 A CN202110314492 A CN 202110314492A CN 113197227 A CN113197227 A CN 113197227A
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Prior art keywords
toothbrush
parts
bactericide
thymol
grape seed
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CN202110314492.1A
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Chinese (zh)
Inventor
高海梅
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Shanghai Naiding Industry And Trade Co ltd
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Shanghai Naiding Industry And Trade Co ltd
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/08Oxygen or sulfur directly attached to an aromatic ring system
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pest Control & Pesticides (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

The invention belongs to the technical field of bactericides, and particularly relates to a bactericide for a toothbrush sterilizing box, which is characterized in that: the raw materials comprise thymol, grape seed powder and replenisher, and the replenisher is prepared from the following components in percentage by mass: 40-50 parts of thymol; 1-10 parts of grape seed powder; 40-60 parts of auxiliary materials. The auxiliary materials in the above components are any one or more of starch or gypsum powder. The bactericide for the toothbrush sterilizing box disclosed by the invention has good sterilizing capability while controlling the production cost, can act on the toothbrush and the toothbrush sterilizing box, effectively inhibits and kills harmful bacteria such as escherichia coli and staphylococcus aureus, and can avoid injuring a user.

Description

Bactericide for toothbrush sterilizing box
Technical Field
The invention belongs to the technical field of bactericides, and particularly relates to a bactericide for a toothbrush sterilizing box.
Background
The toothbrush is one of brushing tools commonly used for cleaning oral cavities, but normally, more than two million bacteria are adhered to a commonly used toothbrush head, which is more than fifty thousand bacteria adhered to a toilet cover on average, because the toothbrush is placed in a bathroom after being used, bacteria are easy to breed, and especially bacteria such as escherichia coli mutant streptococcus, staphylococcus aureus and the like which are common to the toothbrush head are harmful to human bodies.
The patent No. 2018209687785 discloses a toothbrush sterilization box, including base and the box body of setting on the base, be equipped with storing device in the box body, be provided with germicide in the storing device, this germicide can influence the toothbrush of placing in the toothbrush sterilization box, plays the effect of disinfecting. The sterilizing box mainly plays a sterilizing role and is a bactericide which is not specially used for the toothbrush in the existing market, so that the user can be poisoned by contacting with the bactericide when the bactericide is used at any time, or the sterilizing purpose is not clear so as not to kill main harmful bacteria. In addition, the bactericide is used for placing in a sterilizing box of the toothbrush, and the existing effective bactericide cannot be widely spread for practical use due to the overhigh cost.
Disclosure of Invention
The present invention has been made to overcome the above-mentioned disadvantages of the prior art, and an object of the present invention is to provide a disinfectant for a sterilizing case of a toothbrush.
The technical scheme adopted by the invention for solving the technical problems is as follows: a bactericide for a toothbrush sterilizing case, which is characterized in that: the raw materials comprise thymol, grape seed powder and replenisher, and the replenisher is prepared from the following components in percentage by mass: 20-50 parts of thymol; 1-10 parts of grape seed powder; 40-70 parts of auxiliary materials.
Preferably, the bactericide is prepared from the following components in percentage by mass: 45-50 parts of thymol; 1-5 parts of grape seed powder; 45-55 parts of auxiliary materials.
Preferably, the bactericide is prepared from the following components in percentage by mass: 45 parts of thymol; 5 parts of grape seed powder; 50 parts of auxiliary materials.
Preferably, the auxiliary materials in the components are any one or more of starch or gypsum powder.
Compared with the prior art, the invention has the following advantages and effects: the antibacterial toothbrush has good sterilization capability while controlling the cost, can act on the toothbrush and a toothbrush sterilization box, and effectively inhibits and kills harmful bacteria such as escherichia coli, staphylococcus aureus and the like.
Detailed Description
In order to make the aforementioned objects, features and advantages of the present invention more comprehensible, embodiments of the present invention are described in detail below.
1. Selection research of bactericide raw material for toothbrush sterilizing box
The disinfectant described in this embodiment is directed to the toothbrush which is in contact with the oral cavity, and therefore it is desirable that the contact be non-toxic. Is used for a toothbrush sterilizing box. Thymol, also known as thymol, is commonly used in the manufacture of perfumes, pharmaceuticals, indicators, and the like, and has a bacteriostatic effect. Procyanidine is nontoxic, non-carcinogenic and non-antigenic, has better antibacterial property, particularly staphylococcus aureus, is generally extracted from grape seeds, and is replaced by grape seed powder in the selection research, so that the raw material cost can be saved while the effect is ensured.
The bactericide is prepared from the following components in percentage by mass: 20-50 parts of thymol; 1-10 parts of grape seed powder; 40-70 parts of auxiliary materials. The auxiliary material can be any one or mixture of starch or gypsum powder, and plays a role of an excipient, so that the bactericide is convenient to form and press, and simultaneously plays a role of a filler under the condition of fixed dosage.
2. Optimization research of mass ratio of bactericide for toothbrush sterilizing box
Example 1.
The bactericide comprises the following raw materials in parts by weight: 40 parts of thymol; 10 parts of grape seed powder; 50 parts of auxiliary materials. In this example, starch was used as the adjuvant.
The preparation method of the bactericide for the toothbrush sterilizing box comprises the following steps: mixing thymol, grape seed powder and adjuvants, and making into tablet.
The fungicide obtained from the raw material composition of example 1 was tested by the following method.
The detection method comprises the following steps: reference is made to Disinfection Specification (2002 edition) 2.1.5.6.
And (3) testing a sample: a sterilizing toothbrush box.
Test vehicle: a toothbrush.
Treatment before testing: the sterilized toothbrush was placed at room temperature for 1 day after being sterilized, and then placed in the sterilized toothbrush case in which the sterilizer of example 1 was used.
The test results are given in table 1 below.
Figure DEST_PATH_IMAGE001
Example 2.
The bactericide comprises the following raw materials in parts by weight: 20 parts of thymol; 10 parts of grape seed powder; 70 parts of auxiliary materials. In this example, starch was used as the adjuvant.
The preparation method of the bactericide for the toothbrush sterilizing box comprises the following steps: mixing thymol, grape seed powder and adjuvants, and making into tablet.
The fungicide obtained from the raw material composition of example 2 was tested by the following method.
The detection method comprises the following steps: reference is made to Disinfection Specification (2002 edition) 2.1.5.6.
And (3) testing a sample: a sterilizing toothbrush box.
Test vehicle: a toothbrush.
Treatment before testing: the sterilized toothbrush was placed at room temperature for 1 day after being sterilized, and then placed in the sterilized toothbrush case in which the sterilizer of example 2 was used.
The test results are shown in table 2 below.
Figure DEST_PATH_IMAGE002
Example 3.
The bactericide comprises the following raw materials in parts by weight: 30 parts of thymol; 10 parts of grape seed powder; 60 parts of auxiliary materials. In this example, starch was used as the adjuvant.
The preparation method of the bactericide for the toothbrush sterilizing box comprises the following steps: mixing thymol, grape seed powder and adjuvants, and making into tablet.
The fungicide obtained from the raw material composition of example 3 was tested by the following method.
The detection method comprises the following steps: reference is made to Disinfection Specification (2002 edition) 2.1.5.6.
And (3) testing a sample: a sterilizing toothbrush box.
Test vehicle: a toothbrush.
Treatment before testing: the sterilized toothbrush was placed at room temperature for 1 day after being sterilized, and then placed in the sterilized toothbrush case in which the sterilizer of example 3 was used.
The test results are given in table 3 below.
Figure DEST_PATH_IMAGE003
Example 4.
The bactericide comprises the following raw materials in parts by weight: 40 parts of thymol; 1 part of grape seed powder; and (5) 59 parts of auxiliary materials. In this example, starch was used as the adjuvant.
The preparation method of the bactericide for the toothbrush sterilizing box comprises the following steps: mixing thymol, grape seed powder and adjuvants, and making into tablet.
The fungicide obtained from the raw material composition of example 4 was tested by the following method.
The detection method comprises the following steps: reference is made to Disinfection Specification (2002 edition) 2.1.5.6.
And (3) testing a sample: a sterilizing toothbrush box.
Test vehicle: a toothbrush.
Treatment before testing: the sterilized toothbrush was placed at room temperature for 1 day after being sterilized, and then placed in the sterilized toothbrush case in which the sterilizer of example 4 was used.
The test results are given in table 4 below.
Figure DEST_PATH_IMAGE004
Example 5.
The bactericide comprises the following raw materials in parts by weight: 49 parts of thymol; 10 parts of grape seed powder; 41 parts of auxiliary materials. In this example, starch was used as the adjuvant.
The preparation method of the bactericide for the toothbrush sterilizing box comprises the following steps: mixing thymol, grape seed powder and adjuvants, and making into tablet.
The fungicide obtained from the raw material composition of example 5 was tested by the following method.
The detection method comprises the following steps: reference is made to Disinfection Specification (2002 edition) 2.1.5.6.
And (3) testing a sample: a sterilizing toothbrush box.
Test vehicle: a toothbrush.
Treatment before testing: the sterilized toothbrush was placed at room temperature for 1 day after being sterilized, and then placed in the sterilized toothbrush case in which the sterilizer of example 5 was used.
The test results are given in table 5 below.
Figure DEST_PATH_IMAGE005
Example 6.
The bactericide comprises the following raw materials in parts by weight: 43 parts of thymol; 3 parts of grape seed powder; 54 parts of auxiliary materials. In this example, starch was used as the adjuvant.
The preparation method of the bactericide for the toothbrush sterilizing box comprises the following steps: mixing thymol, grape seed powder and adjuvants, and making into tablet.
The fungicide obtained from the raw material composition of example 6 was tested by the following method.
The detection method comprises the following steps: reference is made to Disinfection Specification (2002 edition) 2.1.5.6.
And (3) testing a sample: a sterilizing toothbrush box.
Test vehicle: a toothbrush.
Treatment before testing: the sterilized toothbrush was placed at room temperature for 1 day after being sterilized, and then placed in the sterilized toothbrush case in which the sterilizer of example 6 was used.
The test results are shown in table 6 below.
Figure DEST_PATH_IMAGE006
Example 7.
The bactericide comprises the following raw materials in parts by weight: 50 parts of thymol; 1 part of grape seed powder; 49 parts of auxiliary materials. In this example, starch was used as the adjuvant.
The preparation method of the bactericide for the toothbrush sterilizing box comprises the following steps: mixing thymol, grape seed powder and adjuvants, and making into tablet.
The fungicide obtained from the raw material composition of example 7 was tested by the following method.
The detection method comprises the following steps: reference is made to Disinfection Specification (2002 edition) 2.1.5.6.
And (3) testing a sample: a sterilizing toothbrush box.
Test vehicle: a toothbrush.
Treatment before testing: the sterilized toothbrush was placed at room temperature for 1 day after being sterilized, and then placed in a sterilized toothbrush case in which the sterilizer of example 7 was used.
The test results are given in table 7 below.
Figure DEST_PATH_IMAGE007
Example 8.
The bactericide comprises the following raw materials in parts by weight: 45 parts of thymol; 5 parts of grape seed powder; 50 parts of auxiliary materials. In this example, starch was used as the adjuvant.
The preparation method of the bactericide for the toothbrush sterilizing box comprises the following steps: mixing thymol, grape seed powder and adjuvants, and making into tablet.
The fungicide obtained from the raw material composition of example 8 was tested by the following method.
The detection method comprises the following steps: reference is made to Disinfection Specification (2002 edition) 2.1.5.6.
And (3) testing a sample: a sterilizing toothbrush box.
Test vehicle: a toothbrush.
Treatment before testing: the sterilized toothbrush was placed at room temperature for 1 day after being sterilized, and then placed in the sterilized toothbrush case in which the sterilizer of example 8 was used.
The test results are given in table 8 below.
Figure DEST_PATH_IMAGE008
Example 9.
The bactericide comprises the following raw materials in parts by weight: 50 parts of thymol; 5 parts of grape seed powder; 45 parts of auxiliary materials. In this example, starch was used as the adjuvant.
The preparation method of the bactericide for the toothbrush sterilizing box comprises the following steps: mixing thymol, grape seed powder and adjuvants, and making into tablet.
The fungicide obtained from the raw material composition of example 9 was tested by the following method.
The detection method comprises the following steps: reference is made to Disinfection Specification (2002 edition) 2.1.5.6.
And (3) testing a sample: a sterilizing toothbrush box.
Test vehicle: a toothbrush.
Treatment before testing: the sterilized toothbrush was placed at room temperature for 1 day after being sterilized, and then placed in the sterilized toothbrush case in which the sterilizer of example 9 was used.
The test results are shown in table 9 below.
Figure DEST_PATH_IMAGE009
Based on the tests of the above examples, the bactericide is preferably prepared from the following components in percentage by mass: 45 parts of thymol; 5 parts of grape seed powder; 50 parts of auxiliary materials can save the cost of raw materials while ensuring the sterilization efficiency.
The bactericide for the toothbrush sterilizing box disclosed by the invention has good sterilizing capability while controlling the production cost, and can be used for effectively inhibiting and killing escherichia coli and staphylococcus aureus in a toothbrush and the toothbrush sterilizing box.
The above description of the present invention is intended to be illustrative. Various modifications, additions and substitutions for the specific embodiments described may be made by those skilled in the art without departing from the scope of the invention as defined in the accompanying claims.

Claims (4)

1. A bactericide for a toothbrush sterilizing case, which is characterized in that: the raw materials comprise thymol, grape seed powder and replenisher, and the replenisher is prepared from the following components in percentage by mass:
20-50 parts of thymol;
1-10 parts of grape seed powder;
40-70 parts of auxiliary materials.
2. The bactericide for the toothbrush sterilizing box according to claim 1, which is prepared from the following components in percentage by mass:
45-50 parts of thymol;
1-5 parts of grape seed powder;
45-55 parts of auxiliary materials.
3. The bactericide for the toothbrush sterilizing box as claimed in claim 2, which is prepared from the following components in percentage by mass:
45 parts of thymol;
5 parts of grape seed powder;
50 parts of auxiliary materials.
4. A bactericide for a sterilizing case for toothbrushes according to any one of claims 1 to 3, which is characterized in that: the auxiliary material is any one or more of starch or gypsum powder.
CN202110314492.1A 2021-03-24 2021-03-24 Bactericide for toothbrush sterilizing box Pending CN113197227A (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB788178A (en) * 1955-03-17 1957-12-23 Petrie Tucker A toothbrush container
EP0818160A2 (en) * 1996-07-08 1998-01-14 Kruger, Pieter Josua Hendrik A toothbursh accessory or enclosure
US20070181448A1 (en) * 2006-02-09 2007-08-09 Colin Davis Container for sanitizing an article
US20110183003A1 (en) * 2010-01-27 2011-07-28 Larry Tabb Liquid oral care product geared to disinfect and sterilize a toothbrush head in a collapsible condiment like package
CN103228138A (en) * 2011-01-22 2013-07-31 株式会社Az Disinfection method, disinfection device, and disinfecting agent utilizing light
CN104491840A (en) * 2014-12-30 2015-04-08 中国人民解放军第四军医大学 Oral medicine composition for resisting radiation, preventing dental caries and diminishing inflammation and preparation thereof
CN109363982A (en) * 2018-10-15 2019-02-22 安徽万春日化有限公司 A method of it extracting grape pip-peanut shell-chrysanthemum and prepares toothpaste antimicrobial antiphlogistic antioxidant content

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB788178A (en) * 1955-03-17 1957-12-23 Petrie Tucker A toothbrush container
EP0818160A2 (en) * 1996-07-08 1998-01-14 Kruger, Pieter Josua Hendrik A toothbursh accessory or enclosure
US20070181448A1 (en) * 2006-02-09 2007-08-09 Colin Davis Container for sanitizing an article
US20110183003A1 (en) * 2010-01-27 2011-07-28 Larry Tabb Liquid oral care product geared to disinfect and sterilize a toothbrush head in a collapsible condiment like package
CN103228138A (en) * 2011-01-22 2013-07-31 株式会社Az Disinfection method, disinfection device, and disinfecting agent utilizing light
CN104491840A (en) * 2014-12-30 2015-04-08 中国人民解放军第四军医大学 Oral medicine composition for resisting radiation, preventing dental caries and diminishing inflammation and preparation thereof
CN109363982A (en) * 2018-10-15 2019-02-22 安徽万春日化有限公司 A method of it extracting grape pip-peanut shell-chrysanthemum and prepares toothpaste antimicrobial antiphlogistic antioxidant content

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Application publication date: 20210803