CN113181307A - Radix puerariae and chicory tea substitute drink and preparation method thereof - Google Patents

Radix puerariae and chicory tea substitute drink and preparation method thereof Download PDF

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CN113181307A
CN113181307A CN202110541424.9A CN202110541424A CN113181307A CN 113181307 A CN113181307 A CN 113181307A CN 202110541424 A CN202110541424 A CN 202110541424A CN 113181307 A CN113181307 A CN 113181307A
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powder
chicory
radix puerariae
cyclocarya paliurus
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张贻杨
李英
李安平
王孝平
朱静静
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Shanxi Zhendong Wuhe Health Technology Co ltd
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8967Lilium, e.g. tiger lily or Easter lily
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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Abstract

The invention discloses a kudzuvine root and chicory tea substitute beverage which specifically comprises the following components in parts by weight: 4-6 parts of kudzu root, 1-5 parts of chicory, 1-3 parts of cyclocarya paliurus leaves, 1-3 parts of mulberry leaves, 1-2 parts of lily and 1-2 parts of coix seed; the radix puerariae and chicory tea substitute drink is prepared by crushing, sieving and uniformly mixing radix puerariae, chicory, cyclocarya paliurus leaves, folium mori, lily and semen coicis, and bagging. The radix puerariae and chicory tea substitute disclosed by the invention is prepared by optimally compounding radix puerariae, chicory, folium mori, cyclocarya paliurus leaves, lily and semen coicis according to a monarch, minister, assistant and guide theory, has excellent sensory quality, and can play roles in assisting in reducing uric acid and relieving pain.

Description

Radix puerariae and chicory tea substitute drink and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicine tea, in particular to a kudzuvine root and chicory tea substitute drink and a preparation method thereof.
Background
Uric acid is a metabolite of endogenous purines and dietary purines, and 80% of humans are derived from endogenous purine metabolism and 20% are produced by purine-or nucleic acid-protein-rich food metabolism. Approximately 70% of uric acid produced by human bodies every day is excreted through the kidney, the uric acid level is increased once the uric acid is excessively generated and/or excreted and is reduced, and when the uric acid is continuously increased, the uric acid can be deposited in soft tissues, so that hyperuricemia and gout are induced, the renal function is influenced, and even the life is affected.
With the improvement of living standard of people, the dietary structure and the living style are changed, the phenomena of unreasonable diet and less exercise amount are gradually increased, purine metabolism disorder is caused, and the incidence of hyperuricemia is in a trend of obvious increase in recent years. Therefore, the health care product is necessary for maintaining the normal uric acid of the human body, can well maintain the blood pressure, improve the intelligence, resist oxidative stress and the like when the uric acid is normal, and is beneficial to the healthy development of the human body.
Therefore, providing a radix puerariae and chicory tea substitute drink and a preparation method thereof is a problem which needs to be solved urgently by the technical personnel in the field.
Disclosure of Invention
In view of the above, the invention provides the radix puerariae and chicory tea substitute drink and the preparation method thereof, and the radix puerariae, chicory, mulberry leaves, cyclocarya paliurus leaves, lily and coix seeds are optimally compounded according to the monarch, minister, assistant and guide theory, so that the tea substitute drink not only has excellent sensory quality, but also can play the roles of assisting in reducing uric acid and relieving pain.
In order to achieve the purpose, the invention adopts the following technical scheme:
the invention provides a kudzuvine root and chicory tea substitute beverage which specifically comprises the following components in parts by weight: 4-6 parts of kudzu root, 1-5 parts of chicory, 1-3 parts of cyclocarya paliurus leaves, 1-3 parts of mulberry leaves, 1-2 parts of lily and 1-2 parts of coix seed.
Preferably, the composition specifically comprises the following components in parts by weight: 5 parts of kudzuvine root, 3 parts of chicory, 3 parts of cyclocarya paliurus leaf, 3 parts of mulberry leaf, 1 part of lily and 1 part of coix seed.
Further preferably, the composition specifically comprises the following components in parts by weight: 3 parts of kudzu root, 5 parts of chicory, 3 parts of cyclocarya paliurus leaves, 3 parts of mulberry leaves, 2 parts of lily and 2 parts of coix seeds.
The beneficial effects of the preferred technical scheme are as follows: the kudzu root, the chicory, the cyclocarya paliurus leaves, the mulberry leaves, the lily and the coix seed used in the kudzu root and chicory tea substitute drink have the health-care medicinal functions. Radix Puerariae has effects in expelling pathogenic factors from muscles, relieving fever, promoting salivation, and quenching thirst; chicory can clear liver, promote bile flow, invigorate stomach, promote digestion, induce diuresis and reduce edema; the mulberry leaves can disperse wind and heat, clear away lung heat, moisten dryness, clear liver and improve vision; cyclocarya paliurus leaves have the effects of clearing heat, quenching thirst and detoxifying; lily for nourishing yin, moistening lung, clearing away heart-fire and tranquilizing; yi ren, invigorating spleen and excreting dampness, removing arthralgia and checking diarrhea. The kudzu root, the chicory, the cyclocarya paliurus leaves, the mulberry leaves, the lily and the coix seeds are mutually compatible, so that the effect of reducing uric acid can be achieved.
Wherein radix Puerariae contains flavonoids (including pueraria flavones, puerarin, daidzein, etc.), starch, etc.; it is sweet, pungent and cool in nature; has effects in expelling pathogenic factors from muscles, relieving fever, promoting eruption, promoting salivation, quenching thirst, invigorating yang, and relieving diarrhea; it can be used for treating fever, stiffness and pain of neck and back, measles without adequate eruption, fever thirst, yin deficiency with thirst, dysentery due to heat-purging, and diarrhea due to spleen deficiency.
Chicory mainly contains chemical components such as polysaccharides, terpenoids, flavonoids, phenolic acids and the like; it is slightly bitter, salty and cool; has effects in removing liver heat, promoting bile flow, invigorating stomach, resolving food stagnation, inducing diuresis, and relieving swelling; it can be used for treating jaundice due to damp-heat pathogen, stomach ache, anorexia, edema, and oliguria.
Cyclocarya paliurus leaf contains polysaccharide, flavone, saponin, coumarin, etc.; it is slightly bitter in taste and warm in nature; has effects of dispelling pathogenic wind, relieving inflammation and pain, killing parasite, and relieving itching.
The folium Mori contains rutin, quercetin, isoquercitrin, chlorogenic acid, volatile oil, etc.; it is bitter, sweet and cold in nature; has effects in dispelling pathogenic wind and heat, clearing lung-heat, moistening dryness, suppressing hyperactive liver, improving eyesight, cooling blood, and stopping bleeding; can be used for treating wind-heat type common cold, early stage epidemic febrile disease, cough due to lung heat, vertigo due to hyperactivity of liver-yang, conjunctival congestion, blurred vision, hemoptysis due to recklessly blood flow due to blood heat, and hematemesis.
Bulbus Lilii contains starch, protein, fat, calcium, phosphorus, ferrum and small amount of vitamins, alkaloids, etc.; it is sweet in taste and cold in nature; has effects in nourishing yin, moistening lung, clearing away heart-fire, and tranquilizing mind; can be used for treating dry cough due to yin deficiency, cough with hemoptysis, vexation, pavor, insomnia, dreaminess, absentmindedness, etc.
Coicis semen contains saccharide, fatty oil, amino acids (leucine, lysine, arginine, tyrosine, etc.), and also contains coixol and vitamin B1; it is sweet, bland and slightly cold in flavor; has effects in promoting diuresis, eliminating dampness, invigorating spleen, relieving diarrhea, eliminating dampness, relieving arthralgia, clearing away heat, and expelling pus; it can be used for treating dysuria, edema, tinea pedis, diarrhea due to spleen deficiency, and arthralgia due to wind-dampness.
The invention also provides a preparation method of the radix puerariae and chicory tea substitute beverage, which comprises the following steps:
(1) weighing the raw materials according to the kudzu root and chicory instead of the tea drink for later use;
(2) pulverizing radix Puerariae, herba Cichorii, cyclocarya paliurus leaf, folium Mori, Bulbus Lilii and Coicis semen respectively, and sieving to obtain radix Puerariae powder, herba Cichorii powder, cyclocarya paliurus leaf powder, folium Mori powder, Bulbus Lilii powder and Coicis semen powder;
(3) mixing the radix Puerariae powder, herba Cichorii powder, cyclocarya paliurus leaf powder, folium Mori powder, Bulbus Lilii powder and Coicis semen powder uniformly to obtain semi-finished medicinal powder, and packaging to obtain the radix Puerariae and herba Cichorii tea substitute beverage.
Preferably, the grain sizes of the kudzu root powder, the chicory powder, the cyclocarya paliurus leaf powder, the mulberry leaf powder, the lily powder and the coix seed powder are 20-40 meshes.
The beneficial effects of the preferred technical scheme are as follows: the tea bag prepared by crushing and screening the raw materials of kudzu root, chicory, cyclocarya paliurus leaf, mulberry leaf, lily and coix seed has the light fragrance of mulberry leaf and the bitter aftertaste of medicinal tea, so that people can relax when tasting tea after working compactly; moreover, the whole method is simple to operate and is beneficial to industrial popularization.
Further preferably, the method further comprises the step (4): extracting, concentrating and drying the semi-finished product powder, and then adding auxiliary materials or additives to prepare powder, granules, tablets or capsules.
According to the technical scheme, compared with the prior art, the invention discloses the kudzuvine root and chicory tea substitute beverage and the preparation method thereof, and the kudzuvine root and chicory tea substitute beverage has the following beneficial effects:
(1) the kudzu root, the chicory, the mulberry leaf, the cyclocarya paliurus leaf, the lily and the coix seed are optimally compounded, so that the tea has excellent sensory quality, such as better expression in color, taste and fragrance, and the enjoyment of tea tasting drinking is improved; but also can play the roles of assisting in reducing uric acid and relieving pain; meanwhile, the product has no incompatibility during use and can be used for daily drinking;
(2) the raw materials are prepared into tea bags, and the tea bags have the light fragrance of mulberry leaves and the bitter aftertaste of medicinal tea; when the tea is brewed, the beneficial components in the tea can be quickly and effectively dissolved out, so that the absorption and utilization of the medicinal components are greatly improved; meanwhile, the tea soup after brewing is clear and bright, so that the tea soup is easy to accept;
(3) the preparation method disclosed by the invention is simple to operate and easy to expand production; in addition, the preparation process can retain the effective components in the raw materials, and the obtained product has original taste and flavor.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.
FIG. 1 is a drawing showing the uric acid content of zebra fish treated by the radix puerariae and chicory substitutional tea drink provided by the embodiment of the invention;
in the figure, p <0.01, p <0.001 compared to the model control group;
FIG. 2 is a graph showing the uric acid reducing effect of the kudzu root and chicory substitute tea drink provided by the embodiment of the invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The embodiment 1 of the invention discloses a radix puerariae and chicory tea substitute beverage which specifically comprises the following components in parts by weight:
4-6 parts of kudzu root, 1-5 parts of chicory, 1-3 parts of cyclocarya paliurus leaves, 1-3 parts of mulberry leaves, 1-2 parts of lily and 1-2 parts of coix seed.
The embodiment 1 of the invention also discloses a preparation method of the kudzuvine root and chicory substitutional tea beverage, which comprises the following specific steps:
(1) pulverizing and sieving kudzu root, chicory, cyclocarya paliurus leaves, mulberry leaves, lily and coix seeds respectively, and collecting kudzu root powder, chicory powder, cyclocarya paliurus leaf powder, mulberry leaf powder, lily powder and coix seed powder of 30-50 meshes;
(2) mixing the above radix Puerariae powder, herba Cichorii powder, cyclocarya paliurus leaf powder, folium Mori powder, Bulbus Lilii powder and Coicis semen powder uniformly to obtain semi-finished medicinal powder, and packaging to obtain the radix Puerariae and herba Cichorii tea substitute beverage
Example 2
The embodiment 2 of the invention discloses a radix puerariae and chicory tea substitute beverage which specifically comprises the following components in parts by weight:
5 parts of kudzu root, 3 parts of chicory, 3 parts of cyclocarya paliurus leaves, 3 parts of mulberry leaves, 1 part of lily and 1 part of coix seeds.
The embodiment 2 of the invention also discloses a preparation method of the kudzuvine root and chicory substitutional tea beverage, which comprises the following specific steps:
(1) pulverizing and sieving kudzu root, chicory, cyclocarya paliurus leaves, mulberry leaves, lily and coix seeds respectively, and collecting kudzu root powder, chicory powder, cyclocarya paliurus leaf powder, mulberry leaf powder, lily powder and coix seed powder of 30-50 meshes;
(2) mixing the radix Puerariae powder, herba Cichorii powder, cyclocarya paliurus leaf powder, folium Mori powder, Bulbus Lilii powder and Coicis semen powder uniformly to obtain semi-finished medicinal powder, and packaging according to 3.0g per bag to obtain the radix Puerariae and herba Cichorii tea substitute beverage.
Example 3
The embodiment 3 of the invention discloses a radix puerariae and chicory tea substitute beverage which specifically comprises the following components in parts by weight:
3 parts of kudzu root, 5 parts of chicory, 3 parts of cyclocarya paliurus leaves, 3 parts of mulberry leaves, 2 parts of lily and 2 parts of coix seeds.
The embodiment 3 of the invention also discloses a preparation method of the kudzuvine root and chicory substitute tea beverage, which comprises the following specific steps:
(1) pulverizing and sieving kudzu root, chicory, cyclocarya paliurus leaves, mulberry leaves, lily and coix seeds respectively, and collecting 20-40 meshes kudzu root powder, chicory powder, cyclocarya paliurus leaf powder, mulberry leaf powder, lily powder and coix seed powder;
(2) mixing the radix Puerariae powder, herba Cichorii powder, cyclocarya paliurus leaf powder, folium Mori powder, Bulbus Lilii powder and Coicis semen powder uniformly to obtain semi-finished medicinal powder, and packaging according to 3.5g per bag to obtain the radix Puerariae and herba Cichorii tea substitute beverage.
Effect verification
1. Packet processing
240 tail 5dpf wild type AB strain zebra fish were randomly selected in a six-well plate, and 30 tail zebra fish were treated in each experimental group. The concentrations of 78.1, 156.3, 312.5, 625 and 1250 mug/mL of kudzu root chicory substitute tea drinks and the concentration of 136 mug/mL of allopurinol in a positive control group are respectively dissolved in water, and a model control group and a normal control group are simultaneously arranged, and the capacity of each hole is 3 mL. Except for the normal control group, all the other experimental groups are dissolved in water and then are given potassium oxonate and xanthine sodium salt to establish a zebra fish hyperuricemia model.
2. Statistical detection
1) Observing and counting the death number and the toxic reaction condition of the zebra fish of each experimental group, determining the MTC of the radix puerariae and chicory instead of the tea drink, and obtaining the results as shown in the following table 1;
table 1. radix puerariae and chicory tea substitute drink auxiliary uric acid concentration reduction groping experiment result (n ═ 30)
Figure BDA0003071941650000061
From the above results, it can be seen that under the present experimental conditions, the effect of kudzu root chicory tea substitute drinking in assisting in reducing uric acid was evaluated to be 1250 μ g/mL.
2) Taking three concentration groups of MTC and the following, a positive control group, a model control group and a normal control group, respectively homogenizing each group, taking supernatant, and detecting the content (S) of uric acid in the zebra fish body by using a high performance liquid chromatograph, wherein the obtained result is shown in figure 1.
Chromatographic conditions are as follows: wavelength of detector gamma is 288nm, chromatographic column: shimadzu C18(5 μm 4.6X 250 mm); mobile phase water (0.2% acetic acid): methanol (V: V) ═ 94: 6; the flow rate is 1.0 mL/min; column temperature: 30 ℃; sample introduction amount: 10 μ L.
And evaluating the effect of the radix puerariae and chicory on assisting in reducing uric acid by using the statistical analysis result of the uric acid content. The statistical treatment result is expressed by mean + -SE, and the calculation formula of the auxiliary uric acid reduction effect is as follows:
Figure BDA0003071941650000071
statistical analysis was performed using analysis of variance and Dunnett's T-test, and p <0.05 indicated significant differences, with the results shown in figure 2 and table 2.
TABLE 2 content of uric acid in zebrafish treated with Kudzuvine root chicory tea substitute (n ═ 2)
Figure BDA0003071941650000072
P <0.01, p <0.001, compared to model control group
The experimental results show that the radix puerariae and chicory tea substitute drink prepared by the embodiment of the invention has a remarkable effect of assisting in reducing uric acid.
The embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other. The device disclosed by the embodiment corresponds to the method disclosed by the embodiment, so that the description is simple, and the relevant points can be referred to the method part for description.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (6)

1. The radix puerariae and chicory tea substitute beverage is characterized by comprising the following components in parts by weight: 4-6 parts of kudzu root, 1-5 parts of chicory, 1-3 parts of cyclocarya paliurus leaves, 1-3 parts of mulberry leaves, 1-2 parts of lily and 1-2 parts of coix seed.
2. The radix puerariae and chicory tea substitute beverage as claimed in claim 1 is characterized by comprising the following components in parts by weight: 5 parts of kudzuvine root, 3 parts of chicory, 3 parts of cyclocarya paliurus leaf, 3 parts of mulberry leaf, 1 part of lily and 1 part of coix seed.
3. The radix puerariae and chicory tea substitute beverage as claimed in claim 1 is characterized by comprising the following components in parts by weight: 3 parts of kudzu root, 5 parts of chicory, 3 parts of cyclocarya paliurus leaves, 3 parts of mulberry leaves, 2 parts of lily and 2 parts of coix seeds.
4. A preparation method of a radix puerariae and chicory tea substitute drink is characterized by comprising the following steps:
(1) weighing the raw materials of the kudzu root and chicory tea substitute beverage according to any one of claims 1 to 3 for later use;
(2) pulverizing radix Puerariae, herba Cichorii, cyclocarya paliurus leaf, folium Mori, Bulbus Lilii and Coicis semen respectively, and sieving to obtain radix Puerariae powder, herba Cichorii powder, cyclocarya paliurus leaf powder, folium Mori powder, Bulbus Lilii powder and Coicis semen powder;
(3) mixing the radix Puerariae powder, herba Cichorii powder, cyclocarya paliurus leaf powder, folium Mori powder, Bulbus Lilii powder and Coicis semen powder uniformly to obtain semi-finished medicinal powder, and packaging to obtain the radix Puerariae and herba Cichorii tea substitute beverage.
5. The preparation method of the radix puerariae and chicory tea substitute beverage as claimed in claim 4, wherein the particle sizes of the radix puerariae powder, the chicory powder, the cyclocarya paliurus leaf powder, the mulberry leaf powder, the lily powder and the coix seed powder are 20-50 meshes.
6. The preparation method of the kudzu root chicory tea substitute beverage according to claim 4 or 5, characterized by further comprising the step (4): extracting, concentrating and drying the semi-finished product powder, and then adding auxiliary materials or additives to prepare powder, granules, tablets or capsules.
CN202110541424.9A 2021-05-18 2021-05-18 Radix puerariae and chicory tea substitute drink and preparation method thereof Pending CN113181307A (en)

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CN113876896A (en) * 2021-09-08 2022-01-04 福建中医药大学 Three-rice-drink traditional Chinese medicine formula composition for reducing uric acid and relieving gout and preparation process thereof
CN114848745A (en) * 2022-03-28 2022-08-05 山西振东五和医养堂股份有限公司 Chicory and gardenia beverage and preparation method thereof
CN114931613A (en) * 2022-04-01 2022-08-23 山西振东五和医养堂股份有限公司 Tea substitute beverage with blood pressure lowering effect and preparation method and application thereof
CN115137068A (en) * 2022-07-02 2022-10-04 陈娟 Composition for reducing uric acid and application thereof
CN116159113A (en) * 2022-12-31 2023-05-26 中瑞康安中医药科技发展有限公司 Composition for regulating uric acid to treat gout and preparation method thereof

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113876896A (en) * 2021-09-08 2022-01-04 福建中医药大学 Three-rice-drink traditional Chinese medicine formula composition for reducing uric acid and relieving gout and preparation process thereof
CN113876896B (en) * 2021-09-08 2022-10-14 福建中医药大学 Three-rice-drink traditional Chinese medicine formula composition for reducing uric acid and relieving gout and preparation process thereof
CN114848745A (en) * 2022-03-28 2022-08-05 山西振东五和医养堂股份有限公司 Chicory and gardenia beverage and preparation method thereof
CN114931613A (en) * 2022-04-01 2022-08-23 山西振东五和医养堂股份有限公司 Tea substitute beverage with blood pressure lowering effect and preparation method and application thereof
CN115137068A (en) * 2022-07-02 2022-10-04 陈娟 Composition for reducing uric acid and application thereof
CN116159113A (en) * 2022-12-31 2023-05-26 中瑞康安中医药科技发展有限公司 Composition for regulating uric acid to treat gout and preparation method thereof

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