CN113181302A - 一种用于治疗肾炎的中药 - Google Patents
一种用于治疗肾炎的中药 Download PDFInfo
- Publication number
- CN113181302A CN113181302A CN202110645118.XA CN202110645118A CN113181302A CN 113181302 A CN113181302 A CN 113181302A CN 202110645118 A CN202110645118 A CN 202110645118A CN 113181302 A CN113181302 A CN 113181302A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- traditional chinese
- radix
- treating nephritis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 55
- 201000008383 nephritis Diseases 0.000 title claims abstract description 34
- 241001116757 Pyrrosia lingua Species 0.000 claims abstract description 14
- 240000003146 Lobelia chinensis Species 0.000 claims abstract description 13
- 240000001547 Tadehagi triquetrum Species 0.000 claims abstract description 13
- 235000018958 Gardenia augusta Nutrition 0.000 claims abstract description 11
- 241000522190 Desmodium Species 0.000 claims abstract description 7
- 241000870682 Trigonostemon Species 0.000 claims abstract description 3
- 229930187845 trigonostemon Natural products 0.000 claims abstract description 3
- 239000002994 raw material Substances 0.000 claims description 27
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 22
- 244000111489 Gardenia augusta Species 0.000 claims description 13
- 239000007788 liquid Substances 0.000 claims description 9
- 238000002360 preparation method Methods 0.000 claims description 9
- 239000002775 capsule Substances 0.000 claims description 7
- 239000008187 granular material Substances 0.000 claims description 7
- 239000003826 tablet Substances 0.000 claims description 7
- 239000000706 filtrate Substances 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 238000012545 processing Methods 0.000 claims description 5
- 238000005303 weighing Methods 0.000 claims description 5
- 244000000626 Daucus carota Species 0.000 claims description 4
- 235000005770 birds nest Nutrition 0.000 claims description 4
- 235000005765 wild carrot Nutrition 0.000 claims description 4
- 235000016622 Filipendula ulmaria Nutrition 0.000 claims description 3
- 244000061544 Filipendula vulgaris Species 0.000 claims description 3
- 235000009009 Filipendula vulgaris Nutrition 0.000 claims description 3
- 241001609099 Filifolium Species 0.000 claims description 2
- 210000003608 fece Anatomy 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 10
- 210000003734 kidney Anatomy 0.000 abstract description 6
- 208000002193 Pain Diseases 0.000 abstract description 5
- 208000037157 Azotemia Diseases 0.000 abstract description 3
- 208000009852 uremia Diseases 0.000 abstract description 3
- 238000013461 design Methods 0.000 abstract description 2
- 230000008439 repair process Effects 0.000 abstract description 2
- 240000001972 Gardenia jasminoides Species 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 18
- 230000001737 promoting effect Effects 0.000 description 12
- 206010030113 Oedema Diseases 0.000 description 9
- 230000008961 swelling Effects 0.000 description 9
- 208000024891 symptom Diseases 0.000 description 9
- 208000004880 Polyuria Diseases 0.000 description 7
- 230000035619 diuresis Effects 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- 206010018367 Glomerulonephritis chronic Diseases 0.000 description 5
- 208000006454 hepatitis Diseases 0.000 description 5
- 210000004185 liver Anatomy 0.000 description 5
- 208000019206 urinary tract infection Diseases 0.000 description 5
- 241000699670 Mus sp. Species 0.000 description 4
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 239000011248 coating agent Substances 0.000 description 4
- 238000000576 coating method Methods 0.000 description 4
- 238000001816 cooling Methods 0.000 description 4
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 4
- 239000005556 hormone Substances 0.000 description 4
- 229940088597 hormone Drugs 0.000 description 4
- 210000004072 lung Anatomy 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 235000019658 bitter taste Nutrition 0.000 description 3
- 230000000740 bleeding effect Effects 0.000 description 3
- 235000009508 confectionery Nutrition 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 231100000331 toxic Toxicity 0.000 description 3
- 230000002588 toxic effect Effects 0.000 description 3
- 210000003932 urinary bladder Anatomy 0.000 description 3
- 208000008035 Back Pain Diseases 0.000 description 2
- 206010008909 Chronic Hepatitis Diseases 0.000 description 2
- 206010023126 Jaundice Diseases 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 241000699666 Mus <mouse, genus> Species 0.000 description 2
- 230000005856 abnormality Effects 0.000 description 2
- 235000019606 astringent taste Nutrition 0.000 description 2
- 229940109239 creatinine Drugs 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 210000002216 heart Anatomy 0.000 description 2
- 231100000283 hepatitis Toxicity 0.000 description 2
- 230000027939 micturition Effects 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 235000019633 pungent taste Nutrition 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 235000019640 taste Nutrition 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 206010003445 Ascites Diseases 0.000 description 1
- 241000887125 Chaptalia nutans Species 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 240000009087 Crescentia cujete Species 0.000 description 1
- 235000005983 Crescentia cujete Nutrition 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 241001558017 Gynura Species 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 235000009797 Lagenaria vulgaris Nutrition 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- 206010028372 Muscular weakness Diseases 0.000 description 1
- 206010030124 Oedema peripheral Diseases 0.000 description 1
- 208000005374 Poisoning Diseases 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 208000004078 Snake Bites Diseases 0.000 description 1
- 206010041660 Splenomegaly Diseases 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 241001312519 Trigonella Species 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000007059 acute toxicity Effects 0.000 description 1
- 231100000403 acute toxicity Toxicity 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 238000011888 autopsy Methods 0.000 description 1
- 208000019804 backache Diseases 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 208000019425 cirrhosis of liver Diseases 0.000 description 1
- 230000007012 clinical effect Effects 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 235000012631 food intake Nutrition 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 230000036473 myasthenia Effects 0.000 description 1
- 201000009240 nasopharyngitis Diseases 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 238000000554 physical therapy Methods 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 230000000552 rheumatic effect Effects 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 206010044008 tonsillitis Diseases 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 231100000041 toxicology testing Toxicity 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 231100000611 venom Toxicity 0.000 description 1
- 229940126673 western medicines Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/746—Morinda
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种用于治疗肾炎的中药，本中药配方设计合理，使用安全可靠，通过半边莲、白背根、无根藤、金丝草、金钱草、三角藤、石韦、葫芦茶、栀子、鸟不宿的合理配伍，能明显提高肾炎的疗效，治疗时间短，病人痛苦少，治疗效果好，可有效防止尿毒症的发生，病情能够及时得到控制，并缩短肾修复期。
Description
技术领域
本发明涉及中药技术领域，具体是指一种用于治疗肾炎的中药。
背景技术
肾脏的生理功能主要是排泄代谢产物及调节水、电解质和酸碱平衡，维持机体内环境稳定。肾炎是以肾组织结构发生炎性改变为基本特征，引起不同程度肾功能减退的一组肾脏疾病，可由多种病因引起。肾炎的主要临床症状有：乏力、腰部疼痛、纳差、肉眼血尿、水肿、高血压、肾功能异常、尿量减少、充血性心力衰竭等，给患者带来了很多不便，增加了患者的心理负担。
目前，治疗肾炎的药物存在以下问题：1、治疗作用不明显，易反复，疗效差；2、患者长期进行透析、服用激素类药物及消炎药物，造成体内失调，治疗时间长，极有可能引起尿毒症甚至死亡，反复治疗不愈会给患者带来严重的身体痛苦和经济负担；3、现有的社会上自制的治疗肾炎的药物，疗效不一，安全性、可靠性也较差。
发明内容
本发明要解决的技术问题是克服上述技术的缺陷，提供一种用于治疗肾炎的中药。
为解决上述技术问题，本发明提供的技术方案为一种用于治疗肾炎的中药，包括以下组分：半边莲、白背根、无根藤、金丝草、金钱草、三角藤、石韦、葫芦茶、栀子、鸟不宿。
进一步地，其由以下重量份的组分组成：半边莲5-10份、白背根5-10份、无根藤5-10份、金丝草5-10份、金钱草5-10份、三角藤5-10份、石韦3-12份、葫芦茶5-10份、栀子3-12份、鸟不宿5-10份。
进一步地，其由以下重量份的组分组成：半边莲5份、白背根5份、无根藤5份、金丝草5份、金钱草5份、三角藤5份、石韦3份、葫芦茶5份、栀子3份、鸟不宿5份。
进一步地，其由以下重量份的组分组成：半边莲7份、白背根7份、无根藤7份、金丝草8份、金钱草8份、三角藤7份、石韦9份、葫芦茶7份、栀子9份、鸟不宿8份。
进一步地，其由以下重量份的组分组成：半边莲10份、白背根10份、无根藤10份、金丝草10份、金钱草10份、三角藤10份、石韦12份、葫芦茶10份、栀子12份、鸟不宿10份。
进一步地，所述中药的制备方法包括如下步骤：称取处方量的原料组分，加水煎煮，第一次用水量为原料组分总重的5-10倍，煎煮3-5小时；第二次用水量为原料组分总重的3-8倍，煎煮2-3小时；第三次用水量为原料组分总重的2-5倍，煎煮1-2小时；合并煎煮液并过滤，将滤液浓缩，可进一步加工为口服液、颗粒剂、片剂或胶囊剂。
进一步地，所述中药是口服制剂。
进一步地，所述的口服制剂是口服液、颗粒剂、片剂或胶囊剂。
本发明中所用原料的来源如下：
半边莲：味辛，性平；归心、小肠、肺经；清热解毒，利尿消肿；可用于治疗毒蛇咬伤、肝硬化腹水、肾炎小肿、扁桃体炎。
白背根：味微苦、涩，性平；归肝、脾经；柔肝活血，健脾化湿，收敛固脱；可用于治疗慢性肝炎、脾脏肿大、肠炎腹泻、脱肛、子宫下垂。
无根藤：味甘、微苦，性凉；入肝、肾经；清热利湿，凉血止血；可用于治疗肾炎水肿、尿路结石、肝炎、多发性痛肿。
金丝草：味苦、性寒、无毒；清热解毒；凉血止血；利湿；可用于治疗尿路感染、肾炎水肿。
金钱草：味甘、咸，性微寒；归肝、胆、肾、膀胱经；利湿退黄，利尿通淋，解毒消肿；可用于治疗肾炎水肿、尿路感染、黄疸肝炎。
三角藤：味苦、性寒；清热利水；可用于治疗肾炎水肿、尿路感染结石。
石韦：味甘、苦，性微寒；归肺、膀胱经；有利尿通淋，清肺止咳，凉血止血的功效；可用于治疗肾炎水肿、尿路感染、尿路结石。
葫芦茶：性凉，味苦、涩；归肺经、膀胱经、肝经；清热解毒、利水除湿、消食杀虫；可用于治疗各种热痛、心烦口渴、尿路感染、肾炎水肿。
栀子：味苦、性寒；归心、肺、三焦经；泻火除烦，清热利湿，凉血解毒；可用于治疗黄疸型肝炎、感冒清热、肾炎水肿。
鸟不宿：味辛、涩；祛风除湿、行气止疼、利水；可用于治疗风湿性腰腿疼、急慢性肝炎、肾炎水肿。
本发明与现有技术相比的优点在于：本中药配方设计合理，使用安全可靠，通过半边莲、白背根、无根藤、金丝草、金钱草、三角藤、石韦、葫芦茶、栀子、鸟不宿的合理配伍，能明显提高肾炎的疗效，治疗时间短，病人痛苦少，治疗效果好，可有效防止尿毒症的发生，病情能够及时得到控制，并缩短肾修复期。
具体实施方式
下面结合实施例对本发明一种用于治疗肾炎的中药做进一步的详细说明。
实施例1
按如下重量份称取各原料组分：半边莲5份、白背根5份、无根藤5份、金丝草5份、金钱草5份、三角藤5份、石韦3份、葫芦茶5份、栀子3份、鸟不宿5份，加水煎煮，第一次用水量为原料组分总重的5倍，煎煮3小时；第二次用水量为原料组分总重的3倍，煎煮2小时；第三次用水量为原料组分总重的2倍，煎煮1小时；合并煎煮液并过滤，将滤液浓缩，可进一步加工为口服液、颗粒剂、片剂或胶囊剂。
实施例2
按如下重量份称取各原料组分：半边莲7份、白背根7份、无根藤7份、金丝草8份、金钱草8份、三角藤7份、石韦9份、葫芦茶7份、栀子9份、鸟不宿8份，加水煎煮，第一次用水量为原料组分总重的8倍，煎煮4小时；第二次用水量为原料组分总重的5倍，煎煮3小时；第三次用水量为原料组分总重的3倍，煎煮1小时；合并煎煮液并过滤，将滤液浓缩，可进一步加工为口服液、颗粒剂、片剂或胶囊剂。
实施例3
按如下重量份称取各原料组分：半边莲10份、白背根10份、无根藤10份、金丝草10份、金钱草10份、三角藤10份、石韦12份、葫芦茶10份、栀子12份、鸟不宿10份，加水煎煮，第一次用水量为原料组分总重的10倍，煎煮5小时；第二次用水量为原料组分总重的8倍，煎煮3小时；第三次用水量为原料组分总重的5倍，煎煮2小时；合并煎煮液并过滤，将滤液浓缩，可进一步加工为口服液、颗粒剂、片剂或胶囊剂。
实施例4本发明药物的毒性试验
本试验主要观察动物经口给予本发明的药物产生的急性毒性反应。
本试验的受试动物为小鼠，在试验前，将小鼠置于试验环境中适用一周，在试验期间提供正常的饲料及饮用水，实验室温度：18-22℃，相对湿度：30-50％。
试验过程：将本发明药物煎泡所得液体1日内分3次经口灌服小鼠，每次约5ml，每次间隔4小时，总剂量为15ml，观察小鼠14日内的中毒表现、体重、摄食量及死亡情况。
结果：小鼠经口灌服后表现正常，14日内未见死亡发生，观察期结束后，处死小鼠并进行剖检，各主要脏器未见明显异常。
结论：小鼠每日口服15ml药物煎泡液体，经14日后无死亡发生，同时主要脏器未见明显异常，故该药物属于无毒级。
实施例5本发明药物的临床试验病例
1、肾炎诊断标准
1)患者有头痛、头昏、四肢无力、腰酸背痛、尿蛋白升高等症状；
2)所有病例均为临床确诊为肾炎的患者。
2、疗效判断标准
治愈：上述症状消失，患者感觉腿脚有力，腰部不酸痛；
有效：上述症状减轻，患者偶有不适；
无效：上述症状无明显改善或加重。
3、对比试验分组
为表明本发明药物在治疗肾炎的临床效果，选取200例采用本发明药物治疗肾炎作为试验组，选取200例采用西药的激素类药物作为对照组。
试验组：200例，其中男110例，女90例，年龄阶段为20-60岁，使用本发明药物进行治疗，按上述方法加水煎服，一天一帖，一天分三次服用，十天为一疗程。
对照组：200例，其中男105例，女95例，年龄阶段为20-60岁，使用西药激素类药物进行治疗，用药方法参照药物使用说明书。
从上表可以看出，本发明药物对于肾炎的治疗效果优于西药激素类药物的治疗，且治疗一年内随访，治愈病例中复发率仅为3.5％。
实施例6典型病例
1)郑某，36岁，经医院诊断为综合性肾炎，患者经三年多治疗，治疗过程中仅能暂时性消肿，隔多天后复发，经他人介绍前来治疗，患者前来就医时脸、身、脚部肿胀变形，经本发明药物治疗一个疗程后，肿胀消退，为巩固疗效，患者继续服用本发明药物两个疗程，两年后随访，未见复发。
2)叶某，45岁，福建省田墘君龙头村人，患者患有综合性慢性肾炎6年，遍寻中、西医不能根治，时常复发，给患者身体与精神带来伤害，经他人介绍前来就诊，患者前来就医时，脸部肿胀呈圆形，肚皮隆肿，腿部浮肿严重，患者遵医嘱连续服用本发明药物四个疗程后症状消失，两年后随访，未见复发。
3)郑女士，汕尾市人，患者自十几岁患者慢性肾炎，经医院治疗后暂时性消肿，但复发后症状表现更为严重，常见症状为全身性水肿，经检测蛋白及肌酐数值居高不下，经他人介绍前来就医，遵医嘱服用本发明药物五个疗程，肿胀消失，恢复正常，两年后随访，未见复发。
4)陈女士，汕尾市盐町村人，患者患有慢性肾炎十年左右，经多方寻医找药，始终无法治愈，病情反复发作，经检测蛋白及肌酐数值居高不下，经他人介绍前来寻药，遵医嘱连续服用本发明药物五个疗程，身体恢复健康，至今已有五年，未见复发。
以上对本发明及其实施方式进行了描述，这种描述没有限制性。总而言之如果本领域的普通技术人员受其启示，在不脱离本发明创造宗旨的情况下，不经创造性的设计出与该技术方案相似的结构方式及实施例，均应属于本发明的保护范围。
Claims (8)
1.一种用于治疗肾炎的中药，其特征在于，包括以下组分：半边莲、白背根、无根藤、金丝草、金钱草、三角藤、石韦、葫芦茶、栀子、鸟不宿。
2.根据权利要求1所述的一种用于治疗肾炎的中药，其特征在于，其由以下重量份的组分组成：半边莲5-10份、白背根5-10份、无根藤5-10份、金丝草5-10份、金钱草5-10份、三角藤5-10份、石韦3-12份、葫芦茶5-10份、栀子3-12份、鸟不宿5-10份。
3.根据权利要求1所述的一种用于治疗肾炎的中药，其特征在于，其由以下重量份的组分组成：半边莲5份、白背根5份、无根藤5份、金丝草5份、金钱草5份、三角藤5份、石韦3份、葫芦茶5份、栀子3份、鸟不宿5份。
4.根据权利要求1所述的一种用于治疗肾炎的中药，其特征在于，其由以下重量份的组分组成：半边莲7份、白背根7份、无根藤7份、金丝草8份、金钱草8份、三角藤7份、石韦9份、葫芦茶7份、栀子9份、鸟不宿8份。
5.根据权利要求1所述的一种用于治疗肾炎的中药，其特征在于，其由以下重量份的组分组成：半边莲10份、白背根10份、无根藤10份、金丝草10份、金钱草10份、三角藤10份、石韦12份、葫芦茶10份、栀子12份、鸟不宿10份。
6.根据权利要求1所述的一种用于治疗肾炎的中药，其特征在于，所述中药的制备方法包括如下步骤：称取处方量的原料组分，加水煎煮，第一次用水量为原料组分总重的5-10倍，煎煮3-5小时；第二次用水量为原料组分总重的3-8倍，煎煮2-3小时；第三次用水量为原料组分总重的2-5倍，煎煮1-2小时；合并煎煮液并过滤，将滤液浓缩，可进一步加工为口服液、颗粒剂、片剂或胶囊剂。
7.根据权利要求1所述的一种用于治疗肾炎的中药，其特征在于：所述中药是口服制剂。
8.根据权利要求7所述的一种用于治疗肾炎的中药，其特征在于：所述的口服制剂是口服液、颗粒剂、片剂或胶囊剂。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110645118.XA CN113181302A (zh) | 2021-06-10 | 2021-06-10 | 一种用于治疗肾炎的中药 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110645118.XA CN113181302A (zh) | 2021-06-10 | 2021-06-10 | 一种用于治疗肾炎的中药 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113181302A true CN113181302A (zh) | 2021-07-30 |
Family
ID=76976688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110645118.XA Pending CN113181302A (zh) | 2021-06-10 | 2021-06-10 | 一种用于治疗肾炎的中药 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113181302A (zh) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102106980A (zh) * | 2011-02-25 | 2011-06-29 | 郭迁秋 | 一种治疗尿毒症的药物及制备方法 |
| CN102846986A (zh) * | 2011-06-28 | 2013-01-02 | 潘立芝 | 治疗急性肾盂肾炎的中药制剂 |
| CN112022983A (zh) * | 2020-10-14 | 2020-12-04 | 索绍桢 | 一种治疗肾炎的中药 |
-
2021
- 2021-06-10 CN CN202110645118.XA patent/CN113181302A/zh active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102106980A (zh) * | 2011-02-25 | 2011-06-29 | 郭迁秋 | 一种治疗尿毒症的药物及制备方法 |
| CN102846986A (zh) * | 2011-06-28 | 2013-01-02 | 潘立芝 | 治疗急性肾盂肾炎的中药制剂 |
| CN112022983A (zh) * | 2020-10-14 | 2020-12-04 | 索绍桢 | 一种治疗肾炎的中药 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101703684B (zh) | 一种治疗过敏性紫癜的药物及其制备方法 | |
| CN102847021B (zh) | 一种治疗溃疡性结肠炎的灌肠剂及其制备方法 | |
| CN104547961B (zh) | 一种治疗胆结石的中药组合物 | |
| CN109125559B (zh) | 一种治疗儿童紫癜性肾炎气阴两虚证的中药 | |
| CN106039109A (zh) | 防治寒湿阻络型的类风湿性关节炎的中药药酒 | |
| CN109078156A (zh) | 一种治疗泌尿系统结石用中药及其制备方法 | |
| CN104225346A (zh) | 治疗尿血的中药制剂及制法 | |
| CN100431578C (zh) | 一种治疗前列腺增生的中药制剂 | |
| CN107875233A (zh) | 一种治疗慢性肾小球肾炎的中药组合物及其制备方法 | |
| CN113181302A (zh) | 一种用于治疗肾炎的中药 | |
| CN106138785A (zh) | 一种治疗神经衰弱的中药组合物及其制备方法 | |
| CN108619427B (zh) | 一种预防治疗痛风性关节炎的祛痛降酸药茶 | |
| CN112220846A (zh) | 一种治疗小儿久咳的中药组合物及其应用 | |
| CN104491344A (zh) | 一种中药制剂在制备治疗眼目暴赤肿痛药物中的用途 | |
| CN104225344A (zh) | 治疗慢性肾盂肾炎的中药制剂及制法 | |
| CN107854601A (zh) | 一种治疗顽固性咳、痰、喘的中药组合物及其制备方法 | |
| CN107875284A (zh) | 一种治疗特应性皮炎的中药组合物及其制备方法 | |
| CN102813785B (zh) | 一种治疗头痛型急性肾小球肾炎的中药制备方法 | |
| CN109223951B (zh) | 一种治疗儿童紫癜性肾炎阴虚火旺证的中药 | |
| CN106913669A (zh) | 一种治疗胰腺炎的中药组合物及其应用 | |
| CN105561274A (zh) | 一种用于食管癌的中药制剂及其制备方法 | |
| CN106266970B (zh) | 一种治疗生产引发子宫内膜炎的中药组合物 | |
| CN111214633A (zh) | 一种治疗传染性乙型肝炎的配方 | |
| CN105267498B (zh) | 一种治疗风湿性心脏病的中药组合物 | |
| CN104491206A (zh) | 治疗胆管结石的中药剂及制法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210730 |
|
| RJ01 | Rejection of invention patent application after publication |