CN113166225A - 天然杀伤细胞组合物和治疗肿瘤的免疫疗法方法 - Google Patents

天然杀伤细胞组合物和治疗肿瘤的免疫疗法方法 Download PDF

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CN113166225A
CN113166225A CN201980067523.9A CN201980067523A CN113166225A CN 113166225 A CN113166225 A CN 113166225A CN 201980067523 A CN201980067523 A CN 201980067523A CN 113166225 A CN113166225 A CN 113166225A
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J.B.特拉格
A.J.沈
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Nkarta Inc
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Nkarta Inc
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CN201980067523.9A 2018-09-13 2019-09-11 天然杀伤细胞组合物和治疗肿瘤的免疫疗法方法 Pending CN113166225A (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201862730939P 2018-09-13 2018-09-13
US62/730,939 2018-09-13
US201962821360P 2019-03-20 2019-03-20
US62/821,360 2019-03-20
US201962841768P 2019-05-01 2019-05-01
US62/841,768 2019-05-01
US201962875893P 2019-07-18 2019-07-18
US62/875,893 2019-07-18
PCT/US2019/050679 WO2020056045A1 (en) 2018-09-13 2019-09-11 Natural killer cell compositions and immunotherapy methods for treating tumors

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CN113166225A true CN113166225A (zh) 2021-07-23

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CN201980067523.9A Pending CN113166225A (zh) 2018-09-13 2019-09-11 天然杀伤细胞组合物和治疗肿瘤的免疫疗法方法

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US (2) US20210338727A1 (https=)
EP (1) EP3850004B1 (https=)
JP (2) JP7520818B2 (https=)
CN (1) CN113166225A (https=)
AU (1) AU2019337603B2 (https=)
CA (1) CA3112195A1 (https=)
WO (1) WO2020056045A1 (https=)

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WO2024099265A1 (zh) * 2022-11-07 2024-05-16 上海先博生物科技有限公司 工程化嵌合抗原受体免疫细胞及其应用
CN118406654A (zh) * 2024-04-26 2024-07-30 中国海洋大学 经修饰的nk细胞及其构建方法和应用
CN118440901A (zh) * 2024-04-26 2024-08-06 康立泰生物医药(青岛)有限公司 转基因nk细胞及其构建方法和应用
WO2024254774A1 (zh) * 2023-06-14 2024-12-19 香港北恒生物科技有限公司 免疫细胞联合疗法

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DK3143134T3 (da) 2014-05-15 2021-01-04 Nat Univ Singapore Modificerede, naturlige dræberceller og anvendelser deraf
US11629340B2 (en) 2017-03-03 2023-04-18 Obsidian Therapeutics, Inc. DHFR tunable protein regulation
BR112019019917A2 (pt) 2017-03-27 2020-04-22 Nat Univ Singapore receptores quiméricos nkg2d truncados e seus usos em imunoterapia de células exterminadoras naturais
EP3749685A4 (en) 2018-02-09 2021-12-22 National University of Singapore ACTIVATOR CHEMERIC RECEPTORS AND THEIR USES IN NATURAL KILLING CELL IMMUNOTHERAPY
JP7334985B2 (ja) 2018-04-02 2023-08-29 ナショナル ユニヴァーシティー オブ シンガポール 免疫細胞で発現される膜結合抗サイトカイン非シグナル伝達バインダーによるヒトサイトカインの中和
EP3844186A4 (en) 2018-08-29 2022-08-17 National University of Singapore METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS
EP3773918A4 (en) 2019-03-05 2022-01-05 Nkarta, Inc. CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY
WO2021050789A1 (en) 2019-09-10 2021-03-18 Obsidian Therapeutics, Inc. Ca2-il15 fusion proteins for tunable regulation
CN111423517B (zh) * 2020-04-15 2023-05-12 赛德特生物制药有限公司 一种肿瘤细胞干性限制型car及其应用
AU2021286655A1 (en) 2020-06-12 2023-01-05 Nkarta, Inc. Genetically modified natural killer cells for CD70-directed cancer immunotherapy
WO2022215843A1 (ko) * 2021-04-06 2022-10-13 (주)에스엠티바이오 암 환자에 대하여 자연살해세포를 이용한 면역 항암 치료의 치료 반응성을 예측하는 방법
EP4337228A4 (en) * 2021-05-13 2025-07-30 Nkarta Inc DOSAGE REGIMEN FOR CANCER IMMUNOTHERAPY
US20240316102A1 (en) 2021-07-01 2024-09-26 Indapta Therapeutics, Inc. Engineered natural killer (nk) cells and related methods
JP2024540347A (ja) * 2021-11-09 2024-10-31 ウーゲン，インコーポレイテッド 記憶ｎｋ細胞と抗癌性二重特異性分子とによる組み合わせ癌療法
WO2023199961A1 (ja) * 2022-04-14 2023-10-19 第一三共株式会社 膜型サイトカイン及びｔｎｆ受容体スーパーファミリー分子の細胞内ドメインをコードするポリヌクレオチド
JP2025525439A (ja) 2022-06-30 2025-08-05 インダプタ セラピューティクス インコーポレイテッド 操作されたナチュラルキラー（ｎｋ）細胞と抗体療法との組み合わせおよび関連する方法
WO2024080726A1 (ko) * 2022-10-13 2024-04-18 (주) 테라베스트 자연살해세포 및 토포이소머라제 저해제를 유효성분으로 포함하는 암 예방 및 치료용 약학 조성물
JP2025538424A (ja) * 2022-11-16 2025-11-28 ンカルタ・インコーポレイテッド 併用療法の投与レジメン
WO2025006631A1 (en) * 2023-06-27 2025-01-02 Nkarta, Inc. Dosing regimens for treatment of cancer

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