CN113142367A - 一种鲨鱼软骨素乳钙压片糖果的制备方法 - Google Patents
一种鲨鱼软骨素乳钙压片糖果的制备方法 Download PDFInfo
- Publication number
- CN113142367A CN113142367A CN202110402953.0A CN202110402953A CN113142367A CN 113142367 A CN113142367 A CN 113142367A CN 202110402953 A CN202110402953 A CN 202110402953A CN 113142367 A CN113142367 A CN 113142367A
- Authority
- CN
- China
- Prior art keywords
- shark chondroitin
- milk calcium
- calcium
- chondroitin
- tabletting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title claims abstract description 51
- 239000011575 calcium Substances 0.000 title claims abstract description 51
- 229910052791 calcium Inorganic materials 0.000 title claims abstract description 51
- 235000013336 milk Nutrition 0.000 title claims abstract description 44
- 239000008267 milk Substances 0.000 title claims abstract description 44
- 210000004080 milk Anatomy 0.000 title claims abstract description 44
- 241000251730 Chondrichthyes Species 0.000 title claims abstract description 40
- 229920002567 Chondroitin Polymers 0.000 title claims abstract description 39
- DLGJWSVWTWEWBJ-HGGSSLSASA-N chondroitin Chemical compound CC(O)=N[C@@H]1[C@H](O)O[C@H](CO)[C@H](O)[C@@H]1OC1[C@H](O)[C@H](O)C=C(C(O)=O)O1 DLGJWSVWTWEWBJ-HGGSSLSASA-N 0.000 title claims abstract description 39
- 235000009508 confectionery Nutrition 0.000 title claims abstract description 17
- 238000002360 preparation method Methods 0.000 title claims abstract description 16
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 22
- 239000000203 mixture Substances 0.000 claims abstract description 18
- 238000002156 mixing Methods 0.000 claims abstract description 16
- 239000000049 pigment Substances 0.000 claims abstract description 13
- 238000003756 stirring Methods 0.000 claims abstract description 12
- 235000003599 food sweetener Nutrition 0.000 claims abstract description 9
- 239000003765 sweetening agent Substances 0.000 claims abstract description 9
- 239000003085 diluting agent Substances 0.000 claims abstract description 8
- 239000000853 adhesive Substances 0.000 claims abstract description 7
- 230000001070 adhesive effect Effects 0.000 claims abstract description 7
- 239000000314 lubricant Substances 0.000 claims abstract description 7
- 239000002994 raw material Substances 0.000 claims abstract description 7
- 239000007779 soft material Substances 0.000 claims abstract description 6
- 238000005507 spraying Methods 0.000 claims abstract description 6
- 238000005303 weighing Methods 0.000 claims abstract description 6
- 239000007884 disintegrant Substances 0.000 claims abstract description 4
- 239000008187 granular material Substances 0.000 claims description 19
- 230000001954 sterilising effect Effects 0.000 claims description 16
- 238000001035 drying Methods 0.000 claims description 15
- 238000004659 sterilization and disinfection Methods 0.000 claims description 13
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 12
- 229920002472 Starch Polymers 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 10
- 239000008107 starch Substances 0.000 claims description 10
- 235000019698 starch Nutrition 0.000 claims description 10
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims description 8
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims description 8
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims description 8
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims description 8
- 239000000811 xylitol Substances 0.000 claims description 8
- 235000010447 xylitol Nutrition 0.000 claims description 8
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims description 8
- 229960002675 xylitol Drugs 0.000 claims description 8
- 238000004806 packaging method and process Methods 0.000 claims description 6
- 239000002245 particle Substances 0.000 claims description 6
- 239000000377 silicon dioxide Substances 0.000 claims description 6
- 235000012239 silicon dioxide Nutrition 0.000 claims description 6
- 239000011734 sodium Substances 0.000 claims description 6
- 229910052708 sodium Inorganic materials 0.000 claims description 6
- 238000011049 filling Methods 0.000 claims description 5
- 238000004898 kneading Methods 0.000 claims description 5
- 238000012856 packing Methods 0.000 claims description 5
- 239000000843 powder Substances 0.000 claims description 5
- 238000003825 pressing Methods 0.000 claims description 5
- 238000007873 sieving Methods 0.000 claims description 5
- 238000003892 spreading Methods 0.000 claims description 5
- 230000007480 spreading Effects 0.000 claims description 5
- 229910001220 stainless steel Inorganic materials 0.000 claims description 5
- 239000010935 stainless steel Substances 0.000 claims description 5
- 108010011485 Aspartame Proteins 0.000 claims description 4
- 235000016068 Berberis vulgaris Nutrition 0.000 claims description 4
- 241000335053 Beta vulgaris Species 0.000 claims description 4
- 229920002261 Corn starch Polymers 0.000 claims description 4
- 229920001353 Dextrin Polymers 0.000 claims description 4
- 239000004375 Dextrin Substances 0.000 claims description 4
- 108010010803 Gelatin Proteins 0.000 claims description 4
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 claims description 4
- 239000002202 Polyethylene glycol Substances 0.000 claims description 4
- 244000299461 Theobroma cacao Species 0.000 claims description 4
- 239000000605 aspartame Substances 0.000 claims description 4
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims description 4
- 235000010357 aspartame Nutrition 0.000 claims description 4
- 229960003438 aspartame Drugs 0.000 claims description 4
- 150000001746 carotenes Chemical class 0.000 claims description 4
- 235000005473 carotenes Nutrition 0.000 claims description 4
- 239000008120 corn starch Substances 0.000 claims description 4
- 235000019425 dextrin Nutrition 0.000 claims description 4
- 229920000159 gelatin Polymers 0.000 claims description 4
- 239000008273 gelatin Substances 0.000 claims description 4
- 235000019322 gelatine Nutrition 0.000 claims description 4
- 235000011852 gelatine desserts Nutrition 0.000 claims description 4
- 235000019359 magnesium stearate Nutrition 0.000 claims description 4
- 229920001223 polyethylene glycol Polymers 0.000 claims description 4
- 229920001592 potato starch Polymers 0.000 claims description 4
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 claims description 4
- 239000003795 chemical substances by application Substances 0.000 claims description 3
- SEBIKDIMAPSUBY-ARYZWOCPSA-N Crocin Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O)OC(=O)C(C)=CC=CC(C)=C\C=C\C=C(/C)\C=C\C=C(C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)O1)O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O SEBIKDIMAPSUBY-ARYZWOCPSA-N 0.000 claims description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 2
- 229920002774 Maltodextrin Polymers 0.000 claims description 2
- 239000005913 Maltodextrin Substances 0.000 claims description 2
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 claims description 2
- 239000004376 Sucralose Substances 0.000 claims description 2
- 235000009470 Theobroma cacao Nutrition 0.000 claims description 2
- 239000009627 gardenia yellow Substances 0.000 claims description 2
- 229920003063 hydroxymethyl cellulose Polymers 0.000 claims description 2
- 229940031574 hydroxymethyl cellulose Drugs 0.000 claims description 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 2
- 229940035034 maltodextrin Drugs 0.000 claims description 2
- 229940013618 stevioside Drugs 0.000 claims description 2
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 claims description 2
- 235000019202 steviosides Nutrition 0.000 claims description 2
- 235000019408 sucralose Nutrition 0.000 claims description 2
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 claims description 2
- 239000011230 binding agent Substances 0.000 claims 1
- 229960003943 hypromellose Drugs 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 8
- 206010003246 arthritis Diseases 0.000 abstract description 6
- 239000008280 blood Substances 0.000 abstract description 6
- 210000004369 blood Anatomy 0.000 abstract description 6
- 230000001502 supplementing effect Effects 0.000 abstract description 3
- 208000006820 Arthralgia Diseases 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract 2
- 239000000047 product Substances 0.000 description 10
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 description 7
- 229920001287 Chondroitin sulfate Polymers 0.000 description 7
- 229940059329 chondroitin sulfate Drugs 0.000 description 7
- 229940069978 calcium supplement Drugs 0.000 description 6
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 4
- 230000001276 controlling effect Effects 0.000 description 4
- 230000036541 health Effects 0.000 description 4
- 235000018102 proteins Nutrition 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 238000010521 absorption reaction Methods 0.000 description 3
- 108060003951 Immunoglobulin Proteins 0.000 description 2
- 102000010445 Lactoferrin Human genes 0.000 description 2
- 108010063045 Lactoferrin Proteins 0.000 description 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 2
- 235000005764 Theobroma cacao ssp. cacao Nutrition 0.000 description 2
- 235000005767 Theobroma cacao ssp. sphaerocarpum Nutrition 0.000 description 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 2
- 235000001046 cacaotero Nutrition 0.000 description 2
- 229910000019 calcium carbonate Inorganic materials 0.000 description 2
- FNAQSUUGMSOBHW-UHFFFAOYSA-H calcium citrate Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O FNAQSUUGMSOBHW-UHFFFAOYSA-H 0.000 description 2
- 239000001354 calcium citrate Substances 0.000 description 2
- 239000001506 calcium phosphate Substances 0.000 description 2
- 229910000389 calcium phosphate Inorganic materials 0.000 description 2
- 235000011010 calcium phosphates Nutrition 0.000 description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 description 2
- 210000000845 cartilage Anatomy 0.000 description 2
- 230000003848 cartilage regeneration Effects 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 239000003102 growth factor Substances 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 102000018358 immunoglobulin Human genes 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 description 2
- 235000021242 lactoferrin Nutrition 0.000 description 2
- 229940078795 lactoferrin Drugs 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 239000011574 phosphorus Substances 0.000 description 2
- 229910052698 phosphorus Inorganic materials 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 2
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 2
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 2
- 235000013337 tricalcium citrate Nutrition 0.000 description 2
- 239000011701 zinc Substances 0.000 description 2
- 229910052725 zinc Inorganic materials 0.000 description 2
- MSWZFWKMSRAUBD-UHFFFAOYSA-N 2-Amino-2-Deoxy-Hexose Chemical compound NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 description 1
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- AEMOLEFTQBMNLQ-AQKNRBDQSA-N D-glucopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-AQKNRBDQSA-N 0.000 description 1
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 description 1
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- 229920002683 Glycosaminoglycan Polymers 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 102000014171 Milk Proteins Human genes 0.000 description 1
- 108010011756 Milk Proteins Proteins 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- ZQBZAOZWBKABNC-UHFFFAOYSA-N [P].[Ca] Chemical compound [P].[Ca] ZQBZAOZWBKABNC-UHFFFAOYSA-N 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 230000010100 anticoagulation Effects 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 230000037182 bone density Effects 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 150000002016 disaccharides Chemical class 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000012041 food component Nutrition 0.000 description 1
- 210000004211 gastric acid Anatomy 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 229940097043 glucuronic acid Drugs 0.000 description 1
- 230000036449 good health Effects 0.000 description 1
- 230000005802 health problem Effects 0.000 description 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 210000000867 larynx Anatomy 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000021239 milk protein Nutrition 0.000 description 1
- 210000000537 nasal bone Anatomy 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 238000012858 packaging process Methods 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 235000011888 snacks Nutrition 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229960004793 sucrose Drugs 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/42—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/362—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/46—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing dairy products
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/48—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/26—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by irradiation without heating
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
Abstract
本发明涉及一种鲨鱼软骨素乳钙压片糖果的制备方法，其特征在于，包括以下原材料：鲨鱼软骨素68‑72％、乳钙13‑17％、稀释剂2‑4％、粘合剂2‑4％、崩解剂2‑3％、润滑剂1‑2％、甜味剂0.6‑1％、天然色素0.6‑1％，所述制备方法包括以下步骤：(1)混合：按照比例称取鲨鱼软骨素和乳钙后搅拌混合，再向混合物中加入稀释剂、粘合剂和甜味剂；(2)制粒：向混合后的鲨鱼软骨素和乳钙混合物中边搅拌边喷洒95％乙醇溶液，当混合物料能手捏成团、轻压即散的潮湿程度，将软材经摇摆式制粒机制粒。本发明在压片糖果中加入鲨鱼软骨素与乳钙，产品中的鲨鱼软骨素具有缓解风湿、关节炎、关节痛的作用，乳钙易于人体吸收，调节血钙平衡，是良好的补充钙的来源。
Description
技术领域
本发明涉及鲨鱼软骨素加工技术领域，具体是指一种鲨鱼软骨素乳钙压片糖果的制备方法。
背景技术
鲨鱼软骨素是一种从鲨鱼软骨中提取制备的硫酸软骨素。硫酸软骨素是与蛋白质相结合成糖蛋白的形式存在的，是葡萄糖醛酸和氨基己糖交替连结而成的一种双糖聚合物，是普遍存在于动物的喉骨、鼻中骨和气管等软骨中的一种酸性黏多糖。硫酸软骨素具有多种生物活性，在促进软骨再生、增强机体免疫力、治疗风湿、关节炎等疾病上具有显著的疗效；在临床应用上硫酸软骨素可以使动脉和静脉壁上沉积的脂肪有效地去除或减少从而达到预防动脉粥样硬化的目的；硫酸软骨素还具有降血脂、抗凝血、抗肿瘤等作用。硫酸软骨素在医药和保健方面有着广泛的应用前景，还常用于食品、保健品、化妆品中，可调节皮肤的细胞代谢，保持皮肤的水分抗衰老，促进营养的吸收达到美容的效果等。
乳钙是直接从牛奶中提取出来的纯天然活性高乳蛋白钙，其成分包括柠檬酸钙、磷酸钙、离子钙，还含有锌、磷、蛋白质、免疫球蛋白、生长因子、乳铁蛋白等丰富的营养成分。乳钙在人体内不需要太多胃酸参与即可分离呈现离子状态，进而被人体直接吸收利用，迅速调节血钙平衡，增强体质。乳钙是公认的已知钙质中“生物利用率”极高的食品级钙补充剂，乳钙中还有适量的蛋白和合理的钙磷比例2︰1；同时，因为其生产工艺过程中没有任何化学成分和工艺，对胃肠道没有任何负担，因此乳钙是较适合婴幼儿、孕乳母、儿童、老年人补充钙的来源。
近年来快节奏快速度的现代生活方式与状态引起健康问题的事件越来越多，与此同时人们的健康意识也越来越强，倾向性选择具有良好保健功能的各种食用产品。压片糖果作为我国零食市场中老少皆宜的产品，其样式新颖、形式多变且口感丰富，具有非常强的可塑性，使其在中国消费市场中拥有广阔的发展空间和商业价值，深受各年龄段人群的喜爱。
发明内容
本发明的目的是提供一种鲨鱼软骨素乳钙压片糖果的制备方法，在压片糖果中加入鲨鱼软骨素与乳钙，产品中的鲨鱼软骨素具有缓解风湿、关节炎、关节痛的作用，乳钙易于人体吸收，调节血钙平衡，是良好的补充钙的来源。
为解决上述技术问题，本发明提供的技术方案为：
一种鲨鱼软骨素乳钙压片糖果的制备方法，其特征在于，包括以下原材料：鲨鱼软骨素68-72％、乳钙13-17％、稀释剂2-4％、粘合剂2-4％、崩解剂2-3％、润滑剂1-2％、甜味剂0.6-1％、天然色素0.6-1％，所述制备方法包括以下步骤：
(1)混合：按照比例称取鲨鱼软骨素和乳钙后搅拌混合，再向混合物中加入稀释剂、粘合剂和甜味剂；
(2)制粒：向混合后的鲨鱼软骨素和乳钙混合物中边搅拌边喷洒95％乙醇溶液，当混合物料能手捏成团、轻压即散的潮湿程度，将混合后的软材用手握成团，压过筛网，由筛孔落下的湿颗粒应无细粉和团块，将软材经摇摆式制粒机制粒；
(3)干燥：将湿颗粒均匀铺在不锈钢托盘上，置于60～65℃烘箱中干燥20～30min，干燥过程中每隔一段时间翻动一次颗粒；
(4)整粒：将干燥后的颗粒过14-18目筛除去大颗粒，然后加入崩解剂、润滑剂和天然色素混合均匀；
(5)压片：用75％乙醇擦拭压片冲头，调节压片机填充量至每片0.8-1.2g，控制压力使压片硬度在40-50N进行压片；
(6)包装：将压片好的片剂置于数片机中进行包装；
(7)杀菌：将包装后的产品进行杀菌。
进一步的，所述稀释剂为麦芽糊精、淀粉、糊精、可压性淀粉或硫酸钙中的一种。
进一步的，所述粘合剂为羟甲基纤维素钠、聚乙二醇、羟丙甲纤维素或明胶中的一种。
进一步的，所述崩解剂为玉米淀粉、马铃薯淀粉或羧甲基淀粉钠中的一种。
进一步的，所述润滑剂为二氧化硅或硬脂酸镁中的一种。
进一步的，所述甜味剂为木糖醇、甜菊糖、三氯蔗糖或阿斯巴甜中的一种。
进一步的，所述天然色素为胡萝卜素、可可色素、栀子黄或甜菜红中的一种。
进一步的，所述杀菌方式为辐照杀菌。
采用以上制备方法后，本发明具有如下优点：
鲨鱼软骨素具有促进软骨再生、治疗关节炎等功效，市面上硫酸软骨素产品大多忽视了补钙在缓解关节炎过程中人体补钙和增加骨密度的重要性，本发明中加入鲨鱼软骨素和乳钙使二者相互作用，发挥更好的保健效果；许多补钙产品用碳酸钙作为原料，而人体对碳酸钙的吸收率仅为40％，乳钙作为从牛乳中提取的天然补钙源，除含有檬酸钙、磷酸钙等，还含有锌、磷、蛋白质、免疫球蛋白、生长因子、乳铁蛋白等丰富的营养成分，不仅成分更加安全，而且人体对乳钙的吸收率高达80％；本发明中以木糖醇等代替蔗糖作为甜味剂，木糖醇无需胰岛素的消化，不会引起人体血糖的升高，也避免龋齿的产生；所用色素均为天然提取色素，成分更加健康安全；片剂包装后再进行辐照杀菌处理，与先杀菌再包装相比，能够有效防止包装过程中产生的二次污染；除补钙与缓解关节炎的功效，本发明还具有降血脂、抗凝血、抗肿瘤、增强机体免疫力等保健作用；产品加工成压片糖果，口感丰富，方便携带，适合于各个年龄段的人群食用。
具体实施方式
下面结合实施例对本发明做进一步的详细说明。
实施例一
一种鲨鱼软骨素乳钙压片糖果的制备方法，其特征在于，包括以下原材料：鲨鱼软骨素68％、乳钙17％、糊精2％、聚乙二醇4％、羧甲基淀粉钠5％、二氧化硅2％、木糖醇1％、胡萝卜素1％，所述制备方法包括以下步骤：
(1)混合：按照比例称取68％鲨鱼软骨素和17％乳钙后搅拌混合，再向混合物中加入2％糊精、4％聚乙二醇和1％木糖醇；
(2)制粒：向混合后的鲨鱼软骨素和乳钙混合物中边搅拌边喷洒95％乙醇溶液，当混合物料能手捏成团、轻压即散的潮湿程度，将混合后的软材用手握成团，压过筛网，由筛孔落下的湿颗粒应无细粉和团块，将软材经摇摆式制粒机制粒；
(3)干燥：将湿颗粒均匀铺在不锈钢托盘上，置于60℃烘箱中干燥30min，干燥过程中每隔一段时间翻动一次颗粒；
(4)整粒：将干燥后的颗粒过14目筛除去大颗粒，然后加入5％羧甲基淀粉钠、2％二氧化硅和1％胡萝卜素混合均匀；
(5)压片：用75％乙醇擦拭压片冲头，调节压片机填充量至每片0.8g，控制压力使压片硬度在40N进行压片；
(6)包装：将压片好的片剂置于数片机中进行包装；
(7)杀菌：将包装后的产品进行辐照杀菌。
实施例二
一种鲨鱼软骨素乳钙压片糖果的制备方法，其特征在于，包括以下原材料：鲨鱼软骨素72％、乳钙17％、可压性淀粉2％、羟甲基纤维素钠4％、玉米淀粉3％、硬脂酸镁1％、木糖醇0.6％、甜菜红0.4％，所述制备方法包括以下步骤：
(1)混合：按照比例称取72％鲨鱼软骨素和17％乳钙后搅拌混合，再向混合物中加入2％可压性淀粉、4％羟甲基纤维素钠和0.6％木糖醇；
(2)制粒：向混合后的鲨鱼软骨素和乳钙混合物中边搅拌边喷洒95％乙醇溶液，当混合物料能手捏成团、轻压即散的潮湿程度，将混合后的软材用手握成团，压过筛网，由筛孔落下的湿颗粒应无细粉和团块，将软材经摇摆式制粒机制粒；
(3)干燥：将湿颗粒均匀铺在不锈钢托盘上，置于65℃烘箱中干燥20min，干燥过程中每隔一段时间翻动一次颗粒；
(4)整粒：将干燥后的颗粒过18目筛除去大颗粒，然后加入3％玉米淀粉、1％硬脂酸镁和0.4％甜菜红混合均匀；
(5)压片：用75％乙醇擦拭压片冲头，调节压片机填充量至每片1.2g，控制压力使压片硬度在50N进行压片；
(6)包装：将压片好的片剂置于数片机中进行包装；
(7)杀菌：将包装后的产品进行辐照杀菌。
实施例三
一种鲨鱼软骨素乳钙压片糖果的制备方法，其特征在于，包括以下原材料：鲨鱼软骨素72％、乳钙17％、硫酸钙4％、明胶3％、马铃薯淀粉2％、二氧化硅1％、阿斯巴甜0.5％、可可色素0.5％，所述制备方法包括以下步骤：
(1)混合：按照比例称取72％鲨鱼软骨素和17％乳钙后搅拌混合，再向混合物中加入4％硫酸钙、3％明胶和0.5％阿斯巴甜；
(2)制粒：向混合后的鲨鱼软骨素和乳钙混合物中边搅拌边喷洒95％乙醇溶液，当混合物料能手捏成团、轻压即散的潮湿程度，将混合后的软材用手握成团，压过筛网，由筛孔落下的湿颗粒应无细粉和团块，将软材经摇摆式制粒机制粒；
(3)干燥：将湿颗粒均匀铺在不锈钢托盘上，置于65℃烘箱中干燥20min，干燥过程中每隔一段时间翻动一次颗粒；
(4)整粒：将干燥后的颗粒过18目筛除去大颗粒，然后加入2％马铃薯淀粉、1％二氧化硅和0.5％可可色素混合均匀；
(5)压片：用75％乙醇擦拭压片冲头，调节压片机填充量至每片1g，控制压力使压片硬度在40N进行压片；
(6)包装：将压片好的片剂置于数片机中进行包装；
(7)杀菌：将包装后的产品进行辐照杀菌。
以上所述，仅为本发明较佳的具体实施方式，但本发明的保护范围并不局限于此，任何熟悉本技术领域的技术人员在本发明揭露的技术范围内，根据本发明的技术方案及其发明构思加以等同替换或改变，都应涵盖在本发明的保护范围之内。
Claims (8)
1.一种鲨鱼软骨素乳钙压片糖果的制备方法，其特征在于，包括以下原材料：鲨鱼软骨素68-72％、乳钙13-17％、稀释剂2-4％、粘合剂2-4％、崩解剂2-3％、润滑剂1-2％、甜味剂0.6-1％、天然色素0.6-1％，所述制备方法包括以下步骤：
(1)混合：按照比例称取鲨鱼软骨素和乳钙后搅拌混合，再向混合物中加入稀释剂、粘合剂和甜味剂；
(2)制粒：向混合后的鲨鱼软骨素和乳钙混合物中边搅拌边喷洒95％乙醇溶液，当混合物料能手捏成团、轻压即散的潮湿程度，将混合后的软材用手握成团，压过筛网，由筛孔落下的湿颗粒应无细粉和团块，将软材经摇摆式制粒机制粒；
(3)干燥：将湿颗粒均匀铺在不锈钢托盘上，置于60～65℃烘箱中干燥20～30min，干燥过程中每隔一段时间翻动一次颗粒；
(4)整粒：将干燥后的颗粒过14-18目筛除去大颗粒，然后加入崩解剂、润滑剂和天然色素混合均匀；
(5)压片：用75％乙醇擦拭压片冲头，调节压片机填充量至每片0.8-1.2g，控制压力使压片硬度在40-50N进行压片；
(6)包装：将压片好的片剂置于数片机中进行包装；
(7)杀菌：将包装后的产品进行杀菌。
2.根据权利要求1所述的种鲨鱼软骨素乳钙压片糖果的制备方法，其特征在于，所述稀释剂为麦芽糊精、淀粉、糊精、可压性淀粉或硫酸钙中的一种。
3.根据权利要求1所述的种鲨鱼软骨素乳钙压片糖果的制备方法，其特征在于，所述粘合剂为羟甲基纤维素钠、聚乙二醇、羟丙甲纤维素或明胶中的一种。
4.根据权利要求1所述的种鲨鱼软骨素乳钙压片糖果的制备方法，其特征在于，所述崩解剂为玉米淀粉、马铃薯淀粉或羧甲基淀粉钠中的一种。
5.根据权利要求1所述的种鲨鱼软骨素乳钙压片糖果的制备方法，其特征在于，所述润滑剂为二氧化硅或硬脂酸镁中的一种。
6.根据权利要求1所述的种鲨鱼软骨素乳钙压片糖果的制备方法，其特征在于，所述甜味剂为木糖醇、甜菊糖、三氯蔗糖或阿斯巴甜中的一种。
7.根据权利要求1所述的种鲨鱼软骨素乳钙压片糖果的制备方法，其特征在于，所述天然色素为胡萝卜素、可可色素、栀子黄或甜菜红中的一种。
8.根据权利要求1所述的种鲨鱼软骨素乳钙压片糖果的制备方法，其特征在于，所述杀菌方式为辐照杀菌。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110402953.0A CN113142367A (zh) | 2021-04-15 | 2021-04-15 | 一种鲨鱼软骨素乳钙压片糖果的制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110402953.0A CN113142367A (zh) | 2021-04-15 | 2021-04-15 | 一种鲨鱼软骨素乳钙压片糖果的制备方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113142367A true CN113142367A (zh) | 2021-07-23 |
Family
ID=76890477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110402953.0A Pending CN113142367A (zh) | 2021-04-15 | 2021-04-15 | 一种鲨鱼软骨素乳钙压片糖果的制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113142367A (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114304351A (zh) * | 2021-12-31 | 2022-04-12 | 馨辰生物(广东)有限公司 | 一种牛乳钙片压片糖果 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105432911A (zh) * | 2015-12-02 | 2016-03-30 | 青岛浩大海洋保健食品有限公司 | 一种鲨鱼翅骨粉压片糖果及其制备工艺 |
| CN107307160A (zh) * | 2017-06-29 | 2017-11-03 | 安徽康博特保健食品有限公司 | 一种鲨鱼软骨素乳钙压片糖果的制备方法 |
| CN107865179A (zh) * | 2017-12-27 | 2018-04-03 | 安徽亨博士保健食品有限公司 | 一种乳酸菌乳钙压片糖果及其制备方法 |
| CN111467480A (zh) * | 2020-04-26 | 2020-07-31 | 山东朱氏药业集团有限公司 | 一种氨基葡萄糖硫酸软骨素加钙片及制备方法 |
-
2021
- 2021-04-15 CN CN202110402953.0A patent/CN113142367A/zh active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105432911A (zh) * | 2015-12-02 | 2016-03-30 | 青岛浩大海洋保健食品有限公司 | 一种鲨鱼翅骨粉压片糖果及其制备工艺 |
| CN107307160A (zh) * | 2017-06-29 | 2017-11-03 | 安徽康博特保健食品有限公司 | 一种鲨鱼软骨素乳钙压片糖果的制备方法 |
| CN107865179A (zh) * | 2017-12-27 | 2018-04-03 | 安徽亨博士保健食品有限公司 | 一种乳酸菌乳钙压片糖果及其制备方法 |
| CN111467480A (zh) * | 2020-04-26 | 2020-07-31 | 山东朱氏药业集团有限公司 | 一种氨基葡萄糖硫酸软骨素加钙片及制备方法 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114304351A (zh) * | 2021-12-31 | 2022-04-12 | 馨辰生物(广东)有限公司 | 一种牛乳钙片压片糖果 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106420643B (zh) | 一种含维生素c钠的咀嚼片及其制备方法 | |
| CN103814996B (zh) | 一种红薯渣饼干及其生产方法 | |
| CN106666024B (zh) | 一种富含维生素d2的天然菌粉压片糖果及其制备方法 | |
| CN105166759A (zh) | 一种高膳食纤维椰子粉及其用途 | |
| CN103349046B (zh) | 一种龙舌面包的制作方法 | |
| CN103262983A (zh) | 一种熟化薏仁粉及其加工工艺 | |
| CN103404574A (zh) | 一种葡萄饼干及其制备方法 | |
| CN110604259A (zh) | 一种益生菌桑叶苦荞挂面及其制备方法 | |
| CN104171909A (zh) | 一种菌菇挂面及其制备方法 | |
| CN101564160B (zh) | 防治高血脂高血糖的食品及其制备方法 | |
| CN104431686A (zh) | 一种富硒阿胶菊粉咀嚼片及其制备方法 | |
| CN104161100A (zh) | 一种木薯柠檬饼干及其制作方法 | |
| CN107373274A (zh) | 维生素c泡腾片及其制备方法 | |
| CN113142367A (zh) | 一种鲨鱼软骨素乳钙压片糖果的制备方法 | |
| CN104351646A (zh) | 一种高粱营养保健面条及其生产方法 | |
| CN105580953A (zh) | 一种桑枣压片糖果生产方法 | |
| CN104434937B (zh) | 一种d‑核糖维生素c泡腾片及其制备方法 | |
| CN105410690A (zh) | 一种薏仁紫薯果粥粉及其制作方法 | |
| CN104840949A (zh) | 含鹿骨髓的补骨壮骨保健品 | |
| CN109090319A (zh) | 乳矿物盐压片糖果 | |
| CN1102026C (zh) | 一种鱼杜仲饲料的生产方法 | |
| CN103416579B (zh) | 一种口香糖及其制备方法 | |
| CN1135349A (zh) | 速补钙冲剂 | |
| CN105769659A (zh) | 食用胶原膜及其制备方法 | |
| CN108850064A (zh) | 一种甜玉米磨牙棒及其制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210723 |
|
| RJ01 | Rejection of invention patent application after publication |