CN113116772A - Traditional Chinese medicine wet tissue with sterilizing and inflammation diminishing functions and preparation method thereof - Google Patents

Traditional Chinese medicine wet tissue with sterilizing and inflammation diminishing functions and preparation method thereof Download PDF

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CN113116772A
CN113116772A CN202110248084.0A CN202110248084A CN113116772A CN 113116772 A CN113116772 A CN 113116772A CN 202110248084 A CN202110248084 A CN 202110248084A CN 113116772 A CN113116772 A CN 113116772A
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张殿荣
胡轶平
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208Tissues; Wipes; Patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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    • A61Q19/00Preparations for care of the skin
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    • A61Q19/10Washing or bathing preparations
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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    • A61K2800/30Characterized by the absence of a particular group of ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/805Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95

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Abstract

The invention discloses a traditional Chinese medicine wet tissue with sterilization and inflammation diminishing functions and a preparation method thereof, belonging to the field of wet tissues and comprising a wet tissue carrier and a wet tissue soak solution, wherein the wet tissue carrier is spunlace nonwoven fabric, and the wet tissue soak solution is composed of the following raw materials: lanolin, biguanide hydrochloride, lysozyme, superoxide dismutase, glyceryl stearate, glycerol, bisabolol, benzalkonium chloride, a pH regulator, hydrogenated polyisobutene, caprylic/capric triglyceride, coco betaine, an enzyme compound solution, a traditional Chinese medicine extraction mixed solution and deionized water; the preparation method of the traditional Chinese medicine wet tissue comprises the following steps: preparing an enzyme complex solution, b: preparing a traditional Chinese medicine extract mixed solution, c: enzymolysis of the mixed solution of the traditional Chinese medicine extracts, d: decoloring the traditional Chinese medicine extracting solution, and e: preparing a wet tissue soaking solution, f: soaking; the traditional Chinese medicine wet tissue takes traditional Chinese medicine extract as a main effective component, and is prepared by combining a simple and excellent preparation method, so that the traditional Chinese medicine wet tissue which has the effects of sterilization, antibiosis and antiphlogosis, does not irritate skin and meets the market demand is obtained.

Description

Traditional Chinese medicine wet tissue with sterilizing and inflammation diminishing functions and preparation method thereof
Technical Field
The invention belongs to the field of wet tissues, and particularly relates to a traditional Chinese medicine wet tissue with sterilizing and inflammation diminishing functions and a preparation method thereof.
Background
The wet tissue is a disposable sanitary product prepared by folding, humidifying and packaging a wet-strength soft-fiber high-permeability base material. The wet tissue is taken as a daily skin cleaning article, is convenient to carry and take at any time when going out, becomes an indispensable daily article for people, and is a necessary article for people to go out. Wet wipes on the market can be roughly divided into two categories: one is that the skin care product is sterilized, but cannot sterilize other articles, contains skin care ingredients, and can only be used for moistening and maintaining the skin. The other type is a disinfection wet tissue which not only can be used for disinfecting, but also can be used for disinfecting other articles, and can be used for disinfecting or sterilizing skin scratches, scratches and the like.
At present, traditional Chinese medicine extracting solution is more and more widely applied to daily care products, but due to the limitation of a traditional Chinese medicine extracting mode, the traditional Chinese medicine extracting solution has a good using effect, but is not easy to form uniform liquid by other components due to the defects that the traditional Chinese medicine extracting solution has too many impurities and too thick color, and is easy to precipitate and stratify after being placed for a long time, and the like, so that the traditional Chinese medicine extracting solution is rarely applied to the field of traditional Chinese medicine wet tissues.
Disclosure of Invention
The invention aims to solve the defects that traditional Chinese medicine extracting solution is too much in impurity and too thick in color, precipitates and layers are easy to generate after long-time storage, and other components are not easy to form uniform liquid in the prior art, and provides a traditional Chinese medicine wet tissue with sterilization and inflammation diminishing effects and a preparation method thereof.
The traditional Chinese medicine wet tissue with the functions of sterilization and inflammation diminishing comprises a wet tissue carrier and a wet tissue soaking solution adsorbed on the wet tissue carrier, wherein the wet tissue carrier is a spunlace nonwoven fabric, and the wet tissue soaking solution is composed of the following raw materials in parts by weight: 15-20 parts of lanolin, 2-4 parts of biguanide hydrochloride, 30-40 parts of lysozyme, 40-50 parts of superoxide dismutase, 10-25 parts of glyceryl stearate, 5-8 parts of glycerol, 0.2-0.5 part of bisabolol, 0.2-0.5 part of benzalkonium chloride, 0.5-0.8 part of a pH regulator, 0.5-1 part of hydrogenated polyisobutene, 0.5-1 part of caprylic/capric triglyceride, 1-2 parts of coconut-based oil betaine, 20-28 parts of an enzyme complex solution, 25-35 parts of a traditional Chinese medicine extraction mixed solution and 300 parts of deionized water to 450 parts.
The enzyme compound liquid is prepared from the following raw materials in parts by weight: 5-15 parts of acid protease, 10-15 parts of lipase, 5-15 parts of peptidase, 25-35 parts of pectinase and 150 parts of water.
The traditional Chinese medicine extraction mixed liquor comprises the following components in parts by weight: 3-5 parts of honeysuckle extract, 4-8 parts of phellodendron extract, 2-4 parts of pseudo-ginseng extract, 4-6 parts of mint extract, 12-14 parts of dandelion extract, 3-5 parts of andrographis paniculata extract and 2-4 parts of purslane extract.
The enzyme activity of the lysozyme is 3000U/g, and the enzyme activity of the superoxide dismutase is 20000 IU/g.
The enzyme activity of the acid protease is 50000U/g, the enzyme activity of the lipase is 100000U/g, the enzyme activity of the peptidase is 100000U/g, and the enzyme activity of the pectinase is 100000U/g.
A preparation method of a traditional Chinese medicine wet tissue with sterilization and inflammation diminishing functions comprises the following steps:
step a: preparing an enzyme compound solution: adding 5-15 parts by weight of acid protease, 10-15 parts by weight of lipase, 5-15 parts by weight of peptidase, 25-35 parts by weight of pectinase and 200 parts by weight of water into a stirring barrel, and stirring at 55-70 ℃ for 0.5-1h to prepare an enzyme complex solution;
step b: preparing a mixed solution of the traditional Chinese medicine extracts: adding 3-5 parts by weight of honeysuckle extract, 4-8 parts by weight of phellodendron extract, 2-4 parts by weight of pseudo-ginseng extract, 4-6 parts by weight of mint extract, 12-14 parts by weight of dandelion extract, 3-5 parts by weight of common andrographis herb extract and 2-4 parts by weight of purslane extract into a stirring barrel, and stirring at 55-70 ℃ for 0.5-1h to prepare a traditional Chinese medicine extract mixed solution;
step c: enzymolysis of the mixed solution of the traditional Chinese medicine extracts: mixing the enzyme compound solution prepared in the step a and the mixed solution of the traditional Chinese medicine extract prepared in the step b, and stirring for 1-2h at 55-70 ℃;
step d: decoloring the traditional Chinese medicine extracting solution: and c, adding 20-30 parts by weight of activated carbon and 25-35 parts by weight of activated clay into the mixture obtained in the step c, stirring the mixture for 20-30min at the temperature of 55-70 ℃, and filtering the mixture by using a ceramic membrane to obtain filtrate.
Step e: preparing a wet tissue soaking solution: according to the weight parts, 15-20 parts of lanolin, 2-4 parts of biguanide hydrochloride, 30-40 parts of lysozyme, 40-50 parts of superoxide dismutase, 10-25 parts of glyceryl stearate, 5-8 parts of glycerol, 0.2-0.5 part of bisabolol, 0.2-0.5 part of benzalkonium chloride, 0.5-0.8 part of pH regulator, 0.5-1 part of hydrogenated polyisobutene, 0.5-1 part of caprylic/capric triglyceride, 1-2 parts of coconut-based oil betaine and 450 parts of 300-fold deionized water are added into the filtrate prepared in the step d, and the mixture is stirred for 1-2 hours at the temperature of 55-70 ℃;
step f: and e, soaking the spunlace nonwoven fabrics and the wet tissue soaking solution prepared in the step e in a soaking pool for 3-5 hours, wherein the liquid level of the wet tissue soaking solution is submerged on the surface of the nonwoven fabrics.
The invention has the following advantages:
1. the invention adopts the mixture of various traditional Chinese medicine extracting solutions as the main effective components of the wet tissue soaking solution, and the wet tissue has good sterilizing, antibacterial and anti-inflammatory effects without adding any irritant component based on the antibacterial and anti-inflammatory effects of the traditional Chinese medicines, and simultaneously does not damage the skin;
2. the traditional Chinese medicine extracting solution is subjected to decoloring process treatment, so that the method is simple and convenient, most of colors in the traditional Chinese medicine extracting solution are removed, and the clean appearance of the prepared wet tissue is ensured;
3. the traditional Chinese medicine extracting solution is subjected to enzymolysis through the enzyme compound solution, so that the wet tissue leaching liquor obtained after the traditional Chinese medicine extracting solution is mixed with other components is uniform and stable.
4. The biguanide hydrochloride is added to ensure that the biguanide hydrochloride has good bactericidal effect;
5. biological enzymes such as lysozyme and the like are added, so that the wet tissue is beneficial to skin care;
6. the wet tissue soaking solution has good stability, uniform texture, no visible impurities, and functions of cleaning, caring skin, sterilizing, and diminishing inflammation.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The first embodiment is as follows:
the traditional Chinese medicine wet tissue with the functions of sterilization and inflammation diminishing comprises a wet tissue carrier and a wet tissue soaking solution adsorbed on the wet tissue carrier, wherein the wet tissue carrier is a spunlace nonwoven fabric, and the wet tissue soaking solution is composed of the following raw materials in parts by weight: 18 parts of lanolin, 3 parts of biguanide hydrochloride, 35 parts of lysozyme, 45 parts of superoxide dismutase, 18 parts of glyceryl stearate, 6.5 parts of glycerol, 0.35 part of bisabolol, 0.35 part of benzalkonium chloride, 0.65 part of pH regulator, 0.7 part of hydrogenated polyisobutene, 0.7 part of caprylic/capric triglyceride, 1.5 parts of coconut-based oil betaine, 24 parts of an enzyme complex solution, 30 parts of a traditional Chinese medicine extraction mixed solution and 380 parts of deionized water.
The enzyme compound liquid is prepared from the following raw materials in parts by weight: 10 parts of acid protease, 10 parts of lipase, 10 parts of peptidase, 30 parts of pectinase and 175 parts of water.
The traditional Chinese medicine extraction mixed liquor comprises the following components in parts by weight: 4 parts of honeysuckle extract, 6 parts of phellodendron extract, 3 parts of pseudo-ginseng extract, 5 parts of mint extract, 13 parts of dandelion extract, 4 parts of andrographis paniculata extract and 3 parts of purslane extract.
The enzyme activity of the lysozyme is 3000U/g, and the enzyme activity of the superoxide dismutase is 20000 IU/g.
The enzyme activity of the acid protease is 50000U/g, the enzyme activity of the lipase is 100000U/g, the enzyme activity of the peptidase is 100000U/g, and the enzyme activity of the pectinase is 100000U/g.
A preparation method of a traditional Chinese medicine wet tissue with sterilization and inflammation diminishing functions comprises the following steps:
step a: preparing an enzyme compound solution: adding 10 parts by weight of acid protease, 10 parts by weight of lipase, 10 parts by weight of peptidase, 30 parts by weight of pectinase and 175 parts by weight of water into a stirring barrel, and stirring at 67 ℃ for 0.7h to prepare an enzyme compound solution;
step b: preparing a mixed solution of the traditional Chinese medicine extracts: adding 4 parts by weight of honeysuckle extract, 6 parts by weight of phellodendron extract, 3 parts by weight of pseudo-ginseng extract, 5 parts by weight of mint extract, 13 parts by weight of dandelion extract, 4 parts by weight of common andrographis herb extract and 3 parts by weight of purslane extract into a stirring barrel, and stirring at 38 ℃ for 0.7h to prepare a traditional Chinese medicine extract mixed solution;
step c: enzymolysis of the mixed solution of the traditional Chinese medicine extracts: mixing the enzyme compound solution prepared in the step a and the mixed solution of the traditional Chinese medicine extract prepared in the step b, and stirring for 1.5 hours at 68 ℃;
step d: decoloring the traditional Chinese medicine extracting solution: and c, adding 25 parts by weight of activated carbon and 30 parts by weight of activated clay into the mixture obtained in the step c, stirring the mixture for 25min at 38 ℃, and filtering the mixture by using a ceramic membrane to obtain filtrate.
Step e: preparing a wet tissue soaking solution: according to the weight parts, 18 parts of lanolin, 3 parts of biguanide hydrochloride, 35 parts of lysozyme, 45 parts of superoxide dismutase, 18 parts of glyceryl stearate, 6.5 parts of glycerol, 0.35 part of bisabolol, 0.35 part of benzalkonium chloride, 0.65 part of pH regulator, 0.7 part of hydrogenated polyisobutene, 0.7 part of caprylic/capric triglyceride, 1.5 parts of coconut-based oil betaine and 380 parts of deionized water are added into the filtrate prepared in the step d, and the mixture is stirred for 1.5 hours at 68 ℃;
step f: and e, soaking the spunlace nonwoven fabric and the wet tissue soaking solution prepared in the step e in a soaking pool for 4 hours, wherein the liquid level of the wet tissue soaking solution is over the surface of the nonwoven fabric.
Example two:
the traditional Chinese medicine wet tissue with the functions of sterilization and inflammation diminishing comprises a wet tissue carrier and a wet tissue soaking solution adsorbed on the wet tissue carrier, wherein the wet tissue carrier is a spunlace nonwoven fabric, and the wet tissue soaking solution is composed of the following raw materials in parts by weight: 16 parts of lanolin, 3.5 parts of biguanide hydrochloride, 32 parts of lysozyme, 48 parts of superoxide dismutase, 16 parts of glyceryl stearate, 7 parts of glycerol, 0.25 part of bisabolol, 0.43 part of benzalkonium chloride, 0.75 part of pH regulator, 0.6 part of hydrogenated polyisobutene, 0.7 part of caprylic/capric triglyceride, 1.3 parts of coco betaine, 26 parts of an enzyme complex solution, 32 parts of a traditional Chinese medicine extraction mixed solution and 420 parts of deionized water.
The enzyme compound liquid is prepared from the following raw materials in parts by weight: 8 parts of acid protease, 13 parts of lipase, 8 parts of peptidase, 29 parts of pectinase and 160 parts of water.
The traditional Chinese medicine extraction mixed liquor comprises the following components in parts by weight: 4.5 parts of honeysuckle extract, 5 parts of phellodendron extract, 2.5 parts of pseudo-ginseng extract, 4.5 parts of mint extract, 12 parts of dandelion extract, 3.3 parts of andrographis paniculata extract and 2.7 parts of purslane extract.
The enzyme activity of the lysozyme is 3000U/g, and the enzyme activity of the superoxide dismutase is 20000 IU/g.
The enzyme activity of the acid protease is 50000U/g, the enzyme activity of the lipase is 100000U/g, the enzyme activity of the peptidase is 100000U/g, and the enzyme activity of the pectinase is 100000U/g.
A preparation method of a traditional Chinese medicine wet tissue with sterilization and inflammation diminishing functions comprises the following steps:
step a: preparing an enzyme compound solution: adding 8 parts by weight of acid protease, 13 parts by weight of lipase, 8 parts by weight of peptidase, 29 parts by weight of pectinase and 160 parts by weight of water into a stirring barrel, and stirring at 60 ℃ for 0.8h to prepare an enzyme compound solution;
step b: preparing a mixed solution of the traditional Chinese medicine extracts: adding 4.5 parts by weight of honeysuckle extract, 5 parts by weight of phellodendron extract, 2.5 parts by weight of pseudo-ginseng extract, 4.5 parts by weight of mint extract, 12 parts by weight of dandelion extract, 3.3 parts by weight of common andrographis herb extract and 2.7 parts by weight of purslane extract into a stirring barrel, and stirring at 60 ℃ for 0.8h to prepare a traditional Chinese medicine extract mixed solution;
step c: enzymolysis of the mixed solution of the traditional Chinese medicine extracts: mixing the enzyme compound solution prepared in the step a and the mixed solution of the traditional Chinese medicine extract prepared in the step b, and stirring for 1.2h at the temperature of 60 ℃;
step d: decoloring the traditional Chinese medicine extracting solution: and c, adding 28 parts by weight of activated carbon and 27 parts by weight of activated clay into the mixture obtained in the step c, stirring the mixture at the temperature of 60 ℃ for 28min, and filtering the mixture by using a ceramic membrane to obtain filtrate.
Step e: preparing a wet tissue soaking solution: according to the weight parts, 16 parts of lanolin, 3.5 parts of biguanide hydrochloride, 32 parts of lysozyme, 48 parts of superoxide dismutase, 16 parts of glyceryl stearate, 7 parts of glycerol, 0.25 part of bisabolol, 0.43 part of benzalkonium chloride, 0.75 part of pH regulator, 0.6 part of hydrogenated polyisobutene, 0.7 part of caprylic/capric triglyceride, 1.3 parts of coconut-based oil betaine and 420 parts of deionized water are added into the filtrate prepared in the step d, and the mixture is stirred for 1.8 hours at the temperature of 60 ℃;
step f: and e, soaking the spunlace nonwoven fabric and the wet tissue soaking solution prepared in the step e in a soaking pool for 3 hours, wherein the liquid level of the wet tissue soaking solution is over the surface of the nonwoven fabric.
Example three:
the traditional Chinese medicine wet tissue with the functions of sterilization and inflammation diminishing comprises a wet tissue carrier and a wet tissue soaking solution adsorbed on the wet tissue carrier, wherein the wet tissue carrier is a spunlace nonwoven fabric, and the wet tissue soaking solution is composed of the following raw materials in parts by weight: 15 parts of lanolin, 2 parts of biguanide hydrochloride, 30 parts of lysozyme, 40 parts of superoxide dismutase, 10 parts of glyceryl stearate, 5 parts of glycerol, 0.2 part of bisabolol, 0.2 part of benzalkonium chloride, 0.5 part of a pH regulator, 0.5 part of hydrogenated polyisobutene, 0.5 part of caprylic/capric triglyceride, 1 part of coco betaine, 20 parts of an enzyme complex solution, 25 parts of a traditional Chinese medicine extraction mixed solution and 300 parts of deionized water.
The enzyme compound liquid is prepared from the following raw materials in parts by weight: 5 parts of acid protease, 10 parts of lipase, 5 parts of peptidase, 25 parts of pectinase and 150 parts of water.
The traditional Chinese medicine extraction mixed liquor comprises the following components in parts by weight: 3 parts of honeysuckle extract, 4 parts of phellodendron extract, 2 parts of pseudo-ginseng extract, 4 parts of mint extract, 12 parts of dandelion extract, 3 parts of andrographis paniculata extract and 2 parts of purslane extract.
The enzyme activity of the lysozyme is 3000U/g, and the enzyme activity of the superoxide dismutase is 20000 IU/g.
The enzyme activity of the acid protease is 50000U/g, the enzyme activity of the lipase is 100000U/g, the enzyme activity of the peptidase is 100000U/g, and the enzyme activity of the pectinase is 100000U/g.
A preparation method of a traditional Chinese medicine wet tissue with sterilization and inflammation diminishing functions comprises the following steps:
step a: preparing an enzyme compound solution: adding 5 parts by weight of acid protease, 10 parts by weight of lipase, 5 parts by weight of peptidase, 25 parts by weight of pectinase and 150 parts by weight of water into a stirring barrel, and stirring at 55 ℃ for 0.5h to prepare an enzyme compound solution;
step b: preparing a mixed solution of the traditional Chinese medicine extracts: adding 3 parts by weight of honeysuckle extract, 4 parts by weight of phellodendron extract, 2 parts by weight of pseudo-ginseng extract, 4 parts by weight of mint extract, 12 parts by weight of dandelion extract, 3 parts by weight of common andrographis herb extract and 2 parts by weight of purslane extract into a stirring barrel, and stirring at 55 ℃ for 0.5h to prepare a traditional Chinese medicine extract mixed solution;
step c: enzymolysis of the mixed solution of the traditional Chinese medicine extracts: mixing the enzyme compound solution prepared in the step a and the mixed solution of the traditional Chinese medicine extract prepared in the step b, and stirring for 1h at the temperature of 55 ℃;
step d: decoloring the traditional Chinese medicine extracting solution: and c, adding 20 parts by weight of activated carbon and 25 parts by weight of activated clay into the mixture obtained in the step c, stirring the mixture for 20min at the temperature of 55 ℃, and filtering the mixture by using a ceramic membrane to obtain filtrate.
Step e: preparing a wet tissue soaking solution: according to the weight parts, 15 parts of lanolin, 2 parts of biguanide hydrochloride, 30 parts of lysozyme, 40 parts of superoxide dismutase, 10 parts of glyceryl stearate, 5 parts of glycerol, 0.2 part of bisabolol, 0.2 part of benzalkonium chloride, 0.5 part of pH regulator, 0.5-1 part of hydrogenated polyisobutene, 0.5-1 part of caprylic/capric triglyceride, 1 part of coconut-based oil betaine and 300 parts of deionized water are added into the filtrate prepared in the step d, and the mixture is stirred for 1 hour at the temperature of 55 ℃;
step f: and e, soaking the spunlace nonwoven fabric and the wet tissue soaking solution prepared in the step e in a soaking pool for 3 hours, wherein the liquid level of the wet tissue soaking solution is over the surface of the nonwoven fabric.
Example four:
the traditional Chinese medicine wet tissue with the functions of sterilization and inflammation diminishing comprises a wet tissue carrier and a wet tissue soaking solution adsorbed on the wet tissue carrier, wherein the wet tissue carrier is a spunlace nonwoven fabric, and the wet tissue soaking solution is composed of the following raw materials in parts by weight: 20 parts of lanolin, 4 parts of biguanide hydrochloride, 40 parts of lysozyme, 50 parts of superoxide dismutase, 25 parts of glyceryl stearate, 8 parts of glycerol, 0.5 part of bisabolol, 0.5 part of benzalkonium chloride, 0.8 part of a pH regulator, 1 part of hydrogenated polyisobutene, 1 part of caprylic/capric triglyceride, 2 parts of coconut oil betaine, 28 parts of an enzyme complex solution, 35 parts of a traditional Chinese medicine extraction mixed solution and 450 parts of deionized water.
The enzyme compound liquid is prepared from the following raw materials in parts by weight: 15 parts of acid protease, 15 parts of lipase, 15 parts of peptidase, 35 parts of pectinase and 200 parts of water.
The traditional Chinese medicine extraction mixed liquor comprises the following components in parts by weight: 5 parts of honeysuckle extract, 8 parts of phellodendron extract, 4 parts of pseudo-ginseng extract, 6 parts of mint extract, 14 parts of dandelion extract, 5 parts of andrographis paniculata extract and 4 parts of purslane extract.
The enzyme activity of the lysozyme is 3000U/g, and the enzyme activity of the superoxide dismutase is 20000 IU/g.
The enzyme activity of the acid protease is 50000U/g, the enzyme activity of the lipase is 100000U/g, the enzyme activity of the peptidase is 100000U/g, and the enzyme activity of the pectinase is 100000U/g.
A preparation method of a traditional Chinese medicine wet tissue with sterilization and inflammation diminishing functions comprises the following steps:
step a: preparing an enzyme compound solution: adding 15 parts by weight of acid protease, 15 parts by weight of lipase, 15 parts by weight of peptidase, 35 parts by weight of pectinase and 200 parts by weight of water into a stirring barrel, and stirring for 1h at 70 ℃ to prepare an enzyme compound solution;
step b: preparing a mixed solution of the traditional Chinese medicine extracts: adding 5 parts by weight of honeysuckle extract, 8 parts by weight of phellodendron extract, 4 parts by weight of pseudo-ginseng extract, 6 parts by weight of mint extract, 14 parts by weight of dandelion extract, 5 parts by weight of common andrographis herb extract and 4 parts by weight of purslane extract into a stirring barrel, and stirring for 1h at 70 ℃ to prepare a traditional Chinese medicine extract mixed solution;
step c: enzymolysis of the mixed solution of the traditional Chinese medicine extracts: mixing the enzyme compound solution prepared in the step a and the mixed solution of the traditional Chinese medicine extract prepared in the step b, and stirring for 2 hours at 70 ℃;
step d: decoloring the traditional Chinese medicine extracting solution: and c, adding 30 parts by weight of activated carbon and 35 parts by weight of activated clay into the mixture obtained in the step c, stirring the mixture at 70 ℃ for 30min, and filtering the mixture by using a ceramic membrane to obtain filtrate.
Step e: preparing a wet tissue soaking solution: according to the weight parts, 20 parts of lanolin, 4 parts of biguanide hydrochloride, 40 parts of lysozyme, 50 parts of superoxide dismutase, 25 parts of glyceryl stearate, 8 parts of glycerol, 0.5 part of bisabolol, 0.5 part of benzalkonium chloride, 0.8 part of pH regulator, 1 part of hydrogenated polyisobutene, 1 part of caprylic/capric triglyceride, 2 parts of coconut oil betaine and 450 parts of deionized water are added into the filtrate prepared in the step d, and the mixture is stirred for 2 hours at 70 ℃;
step f: and e, soaking the spunlace nonwoven fabric and the wet tissue soaking solution prepared in the step e in a soaking pool for 5 hours, wherein the liquid level of the wet tissue soaking solution is over the surface of the nonwoven fabric.
Control sample:
the specifications on the purchase market are marked with the wet tissue with the antibacterial and anti-inflammatory effects.
The use effect of the wet tissue prepared based on the above example is as follows:
Figure BDA0002964900800000111
Figure BDA0002964900800000121
based on the using effects, the antibacterial and anti-inflammatory traditional Chinese medicine wet tissue provided by the invention is far higher in antibacterial and sterilizing effects than those of wet tissues in the prior art, and the traditional Chinese medicine wet tissue is good in moisture retention and free of stimulation to skin.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (6)

1. The traditional Chinese medicine wet tissue with the functions of sterilization and inflammation diminishing is characterized by comprising a wet tissue carrier and a wet tissue soaking solution adsorbed on the wet tissue carrier, wherein the wet tissue carrier is a spunlace nonwoven fabric, and the wet tissue soaking solution is composed of the following raw materials in parts by weight: 15-20 parts of lanolin, 2-4 parts of biguanide hydrochloride, 30-40 parts of lysozyme, 40-50 parts of superoxide dismutase, 10-25 parts of glyceryl stearate, 5-8 parts of glycerol, 0.2-0.5 part of bisabolol, 0.2-0.5 part of benzalkonium chloride, 0.5-0.8 part of a pH regulator, 0.5-1 part of hydrogenated polyisobutene, 0.5-1 part of caprylic/capric triglyceride, 1-2 parts of coconut-based oil betaine, 20-28 parts of an enzyme complex solution, 25-35 parts of a traditional Chinese medicine extraction mixed solution and 300 parts of deionized water to 450 parts.
2. The traditional Chinese medicine wet tissue with sterilization and inflammation diminishing functions as claimed in claim 1, wherein the enzyme compound liquid is composed of the following raw materials in parts by weight: 5-15 parts of acid protease, 10-15 parts of lipase, 5-15 parts of peptidase, 25-35 parts of pectinase and 150 parts of water.
3. The traditional Chinese medicine wet tissue with sterilization and inflammation diminishing functions as claimed in claim 1, wherein the traditional Chinese medicine extraction mixed solution comprises the following components in parts by weight: 3-5 parts of honeysuckle extract, 4-8 parts of phellodendron extract, 2-4 parts of pseudo-ginseng extract, 4-6 parts of mint extract, 12-14 parts of dandelion extract, 3-5 parts of andrographis paniculata extract and 2-4 parts of purslane extract.
4. The bactericidal and anti-inflammatory traditional Chinese medicine wet tissue as claimed in claim 1, wherein the enzyme activity of lysozyme is 3000U/g, and the enzyme activity of superoxide dismutase is 20000 IU/g.
5. The bactericidal and anti-inflammatory traditional Chinese medicine wet tissue as claimed in claim 2, wherein the enzyme activity of the acid protease is 50000U/g, the enzyme activity of the lipase is 100000U/g, the enzyme activity of the peptidase is 100000U/g, and the enzyme activity of the pectinase is 100000U/g.
6. A method for preparing the sterilizing and inflammation diminishing traditional Chinese medicine wet tissue as claimed in any one of claims 1 to 5,
step a: preparing an enzyme compound solution: adding 5-15 parts by weight of acid protease, 10-15 parts by weight of lipase, 5-15 parts by weight of peptidase, 25-35 parts by weight of pectinase and 200 parts by weight of water into a stirring barrel, and stirring at 55-70 ℃ for 0.5-1h to prepare an enzyme complex solution;
step b: preparing a mixed solution of the traditional Chinese medicine extracts: adding 3-5 parts by weight of honeysuckle extract, 4-8 parts by weight of phellodendron extract, 2-4 parts by weight of pseudo-ginseng extract, 4-6 parts by weight of mint extract, 12-14 parts by weight of dandelion extract, 3-5 parts by weight of common andrographis herb extract and 2-4 parts by weight of purslane extract into a stirring barrel, and stirring at 55-70 ℃ for 0.5-1h to prepare a traditional Chinese medicine extract mixed solution;
step c: enzymolysis of the mixed solution of the traditional Chinese medicine extracts: mixing the enzyme compound solution prepared in the step a and the mixed solution of the traditional Chinese medicine extract prepared in the step b, and stirring for 1-2h at 55-70 ℃;
step d: decoloring the traditional Chinese medicine extracting solution: adding 20-30 parts by weight of activated carbon and 25-35 parts by weight of activated clay into the step c, stirring the mixture at the temperature of 55-70 ℃ for 20-30min, and filtering the mixture by using a ceramic membrane to prepare filtrate;
step e: preparing a wet tissue soaking solution: according to the weight parts, 15-20 parts of lanolin, 2-4 parts of biguanide hydrochloride, 30-40 parts of lysozyme, 40-50 parts of superoxide dismutase, 10-25 parts of glyceryl stearate, 5-8 parts of glycerol, 0.2-0.5 part of bisabolol, 0.2-0.5 part of benzalkonium chloride, 0.5-0.8 part of pH regulator, 0.5-1 part of hydrogenated polyisobutene, 0.5-1 part of caprylic/capric triglyceride, 1-2 parts of coconut-based oil betaine and 450 parts of 300-fold deionized water are added into the filtrate prepared in the step d, and the mixture is stirred for 1-2 hours at the temperature of 55-70 ℃;
step f: and e, soaking the spunlace nonwoven fabrics and the wet tissue soaking solution prepared in the step e in a soaking pool for 3-5 hours, wherein the liquid level of the wet tissue soaking solution is submerged on the surface of the nonwoven fabrics.
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Application publication date: 20210716