CN113082126A - Preparation method of dampness-removing itching-relieving lotion - Google Patents

Preparation method of dampness-removing itching-relieving lotion Download PDF

Info

Publication number
CN113082126A
CN113082126A CN202110468346.4A CN202110468346A CN113082126A CN 113082126 A CN113082126 A CN 113082126A CN 202110468346 A CN202110468346 A CN 202110468346A CN 113082126 A CN113082126 A CN 113082126A
Authority
CN
China
Prior art keywords
parts
liquid
weight
water
residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202110468346.4A
Other languages
Chinese (zh)
Inventor
高洪波
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sichuan Tongyuan Pharmaceutical Group Co ltd
Original Assignee
Sichuan Tongyuan Pharmaceutical Group Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sichuan Tongyuan Pharmaceutical Group Co ltd filed Critical Sichuan Tongyuan Pharmaceutical Group Co ltd
Priority to CN202110468346.4A priority Critical patent/CN113082126A/en
Publication of CN113082126A publication Critical patent/CN113082126A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234Cnidium (snowparsley)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/758Zanthoxylum, e.g. pricklyash
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/86Violaceae (Violet family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/37Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a preparation method of a dehumidifying and itching-relieving lotion, which comprises the following steps: (1) mixing fructus Cnidii, fructus Zanthoxyli and rhizoma Atractylodis to form composition A, adding 16 times of water, distilling to extract aromatic water, and separating residue and liquid to obtain medicinal residue and medicinal liquid A; (2) mixing Coptidis rhizoma, cortex Phellodendri, cortex Dictamni Radicis, radix Sophorae Flavescentis, rhizoma Polygoni Cuspidati, herba Violae, Kochiae fructus, herba Polygoni Avicularis and herba Artemisiae Scopariae to form composition B, decocting the residue and composition B in water for 2 times, mixing decoctions, and filtering to obtain liquid medicine B; (3) mixing the liquid medicine A and the liquid medicine B and then concentrating; filtering the concentrated medicinal liquid, adding aromatic water and Borneolum Syntheticum, stirring, adding citric acid to adjust pH, adding purified water to make the total volume of the liquid 1000 parts, mixing, filtering, packaging, and sterilizing. The dampness removing and itching relieving lotion prepared by the invention is yellow brown liquid, has borneol fragrance, and is used for the adjuvant treatment of acute and subacute eczema syndromes of damp-heat or damp-blocking type.

Description

Preparation method of dampness-removing itching-relieving lotion
Technical Field
The invention relates to the technical field of dehumidification and itching relieving, and particularly relates to a preparation method of a dehumidification and itching relieving lotion.
Background
Eczema is caused by various internal and external factors, and is a common allergic, non-infectious and allergic inflammatory skin disease of the epidermis and the superficial dermis of the skin. The eczema is mainly developed in four limbs, has the characteristics of symmetry, exudation, pruritus, polymorphism, recurrence and the like in clinical expression, and is refractory to skin pruritus during the onset of the eczema. The main symptoms of eczema include erythema, papules, blisters, etc., which may cause severe itching, local exudation and erosion after scratching, and infection with suppuration, which may cause recurrent attacks.
The records of traditional Chinese medical science and the clinical practice of traditional Chinese medicine prove that the plant extract with the functions of relieving itching and removing dampness has certain functions of relieving or treating eczema symptoms. Chinese plant resources are rich, the history of herbal medicines is long, the plant medicines for relieving itching and removing dampness comprise phellodendron, rhizoma atractylodis, radix sophorae flavescentis, plantain, fructus cnidii, scutellaria baicalensis and coptis chinensis, the plant medicines have the functions of clearing heat and promoting diuresis and cooling blood, and the volatile oil of the plant medicines comprises mint, chrysanthemum, folium artemisiae argyi, clove, agastache rugosus, lavender, honeysuckle and the like, and has the effects of cooling and relieving itching; therefore, a dehumidifying and itching-relieving lotion containing traditional Chinese medicine components is urgently needed.
In view of this, the present patent is applied.
Disclosure of Invention
The invention aims to provide a preparation method of a dehumidifying and itching-relieving lotion with pure traditional Chinese medicine components, the dehumidifying and itching-relieving lotion prepared by the method is a yellow-brown liquid with borneol fragrance, and is used for the adjuvant treatment of acute and subacute eczema syndromes of damp-heat or damp-block type.
In order to achieve the purpose, the invention adopts the following technical scheme:
a preparation method of a dehumidifying and itching-relieving lotion comprises the following steps:
(1) mixing 45 parts of fructus cnidii, 5 parts of pepper and 10 parts of rhizoma atractylodis according to the parts by weight to form a composition A, adding water which is 16 times of the total mass of the composition A, distilling to extract aromatic water, and performing residue-liquid separation after distillation to obtain medicine residue and medicine liquid A;
(2) mixing 10 parts by weight of coptis chinensis, 10 parts by weight of golden cypress, 15 parts by weight of cortex dictamni, 15 parts by weight of radix sophorae flavescentis, 20 parts by weight of polygonum cuspidatum, 20 parts by weight of philippine violet herb, 25 parts by weight of fructus kochiae, 15 parts by weight of polygonum aviculare and 15 parts by weight of oriental wormwood to form a composition B, adding water into the residue obtained after residue-liquid separation in the step (1) and the composition B, decocting for 2 times, 1 hour each time, 12 times of the amount of the residue added for the first time and 8 times of the amount;
(3) mixing the liquid medicine A obtained after the residue-liquid separation in the step (1) with the liquid medicine B obtained in the step (2), and concentrating the mixture until the relative density is 1.04-1.06; standing for 24h, filtering the concentrated liquid medicine, adding the aromatic water and borneol prepared in the step (1) into the filtered liquid medicine, fully stirring, adding citric acid to adjust the pH value to 5, adding purified water to make the total volume of the liquid be 1000 parts, uniformly mixing, standing for 24h, filtering, subpackaging and sterilizing.
Further, the distillation extraction of aromatic water in the step (1) is specifically operated as follows: firstly soaking the composition A0.5h, then introducing steam with the pipeline pressure of 0.2Mpa, carrying out steam distillation, starting cooling water, distilling and collecting 500 parts by total mass of aromatic water, and then stopping distillation.
Further, the extracted aromatic water is stored in a refrigeration house with the temperature of 2-8 ℃.
Further, in the step (2), the composition B and the decoction dregs in the step (1) are soaked for 0.5h before the first decoction.
Further, the concentration in the step (3) adopts a double-effect concentrator, the pressure in the first-effect concentrator is-0.04 to-0.06 MPa, the temperature is 85 +/-5 ℃, the pressure in the second-effect concentrator is-0.06 to-0.08 MPa, and the temperature is 65 +/-5 ℃.
Further, the borneol solution prepared in the step (3) is prepared by adding 4 parts by mass of borneol into 50 parts by mass of 95% ethanol.
Detailed Description
The preparation method of the dehumidifying and itching-relieving lotion provided by the embodiment comprises the following steps:
(1) 225kg of fructus cnidii, 25kg of pepper and 50kg of rhizoma atractylodis are mixed according to the weight part to form a composition A, namely a distilled composition, drinking water with the total mass 16 times of that of the composition A is added, the composition A is soaked for 0.5 hour, then steam with the pipeline pressure of 0.2Mpa is introduced for steam distillation, the steam pressure is less than or equal to 0.12Mpa, cooling water is started, and the distillation is stopped after the total volume of aromatic water collected by distillation is 2500L; storing the extracted aromatic water in a refrigeration house at the temperature of 2-8 ℃, and performing residue-liquid separation after distillation to obtain medicine residue and medicine liquid A; filtering the liquid medicine A by a sieve of 80 meshes, and then filtering the liquid medicine A by a sieve of 200 meshes for later use;
(2) mixing 50kg of coptis chinensis, 50kg of phellodendron, 75kg of cortex dictamni, 75kg of radix sophorae flavescentis, 100kg of polygonum cuspidatum, 100kg of Chinese violet, 125kg of fructus kochiae, 75kg of polygonum aviculare and 75kg of oriental wormwood according to parts by weight to form a composition B, namely a decoction composition, adding water into the residue obtained after residue-liquid separation in the step (1) and the composition B for decocting for 2 times, adding 12 times of water for soaking for 0.5h each time for 1h, then starting decoction, adding 8 times of water for the second time, combining the decoctions, filtering to obtain a liquid medicine B, filtering the liquid medicine B through a 80-mesh sieve, then filtering through a 200-mesh sieve, adding the liquid medicine A in;
(3) mixing the liquid medicine B obtained in the step (2) and the liquid medicine A obtained in the step (1), pumping the mixture into a double-effect concentrator to concentrate the mixture until the relative density is 1.04-1.06, the pressure in a first-effect concentrator is-0.04-0.06 MPa, the temperature is 85 +/-5 ℃, the pressure in a second-effect concentrator is-0.06-0.08 MPa, the temperature is 65 +/-5 ℃, and the extract yield after detection and concentration is 65.0-75.0%; standing for 24h, filtering the concentrated liquid medicine, adding 2500L of aromatic water and 50L of borneol in the step (1) into the filtered liquid medicine, fully stirring, adding 0.5kg of citric acid to adjust the pH value to 5, adding purified water to make the total volume of the liquid be 1000 parts, uniformly mixing, standing for 24h, filtering, subpackaging and sterilizing.
The borneol preparation liquid in the step (3) is prepared by adding 50L of 95% ethanol into 4kg of borneol in parts by mass.
The dehumidifying and itching-relieving lotion prepared in the embodiment is a yellow-brown liquid with borneol fragrance; clear heat, remove dampness, dispel wind and relieve itching. Can be used for the adjuvant treatment of acute and subacute eczema due to damp-heat or damp obstruction. The use method comprises the following steps: the external preparation is applied to the affected part 3-4 times a day; or diluting with water by 10 times and bathing.
The above description is only a preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any modification and replacement based on the technical solution and inventive concept provided by the present invention should be covered within the scope of the present invention.

Claims (6)

1. A preparation method of a dehumidifying and itching-relieving lotion is characterized by comprising the following steps:
(1) mixing 45 parts of fructus cnidii, 5 parts of pepper and 10 parts of rhizoma atractylodis according to the parts by weight to form a composition A, adding water which is 16 times of the total mass of the composition A, distilling to extract aromatic water, and performing residue-liquid separation after distillation to obtain medicine residue and medicine liquid A;
(2) mixing 10 parts by weight of coptis chinensis, 10 parts by weight of golden cypress, 15 parts by weight of cortex dictamni, 15 parts by weight of radix sophorae flavescentis, 20 parts by weight of polygonum cuspidatum, 20 parts by weight of philippine violet herb, 25 parts by weight of fructus kochiae, 15 parts by weight of polygonum aviculare and 15 parts by weight of oriental wormwood to form a composition B, adding water into the residue obtained after residue-liquid separation in the step (1) and the composition B, decocting for 2 times, 1 hour each time, 12 times of the amount of the residue added for the first time and 8 times of the amount;
(3) mixing the liquid medicine A obtained after the residue-liquid separation in the step (1) with the liquid medicine B obtained in the step (2), and concentrating the mixture until the relative density is 1.04-1.06; standing for 24h, filtering the concentrated liquid medicine, adding the aromatic water and borneol prepared in the step (1) into the filtered liquid medicine, fully stirring, adding citric acid to adjust the pH value to 5, adding purified water to make the total volume of the liquid be 1000 parts, uniformly mixing, standing for 24h, filtering, subpackaging and sterilizing.
2. The method for preparing a dehumidifying itching-relieving lotion according to claim 1, wherein: the operation of distilling and extracting the aromatic water in the step (1) is as follows: firstly soaking the composition A0.5h, then introducing steam with the pipeline pressure of 0.2Mpa, carrying out steam distillation, starting cooling water, distilling and collecting 500 parts by total mass of aromatic water, and then stopping distillation.
3. The method for preparing a dehumidifying itching-relieving lotion according to claim 1 or 2, characterized in that: the extracted aromatic water is stored in a refrigeration house with the temperature of 2-8 ℃.
4. The method for preparing a dehumidifying itching-relieving lotion according to claim 1, wherein: soaking the composition B and the decoction dregs in the step (1) for 0.5h before the first decoction in the step (2).
5. The method for preparing a dehumidifying itching-relieving lotion according to claim 1, wherein: and (3) concentrating by adopting a double-effect concentrator, wherein the pressure in the first-effect concentrator is-0.04 to-0.06 MPa, the temperature is 85 +/-5 ℃, the pressure in the second-effect concentrator is-0.06 to-0.08 MPa, and the temperature is 65 +/-5 ℃.
6. The method for preparing a dehumidifying itching-relieving lotion according to claim 1, wherein: the borneol preparation liquid in the step (3) is prepared by adding 4 parts by mass of borneol into 50 parts by mass of 95% ethanol.
CN202110468346.4A 2021-04-28 2021-04-28 Preparation method of dampness-removing itching-relieving lotion Pending CN113082126A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110468346.4A CN113082126A (en) 2021-04-28 2021-04-28 Preparation method of dampness-removing itching-relieving lotion

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110468346.4A CN113082126A (en) 2021-04-28 2021-04-28 Preparation method of dampness-removing itching-relieving lotion

Publications (1)

Publication Number Publication Date
CN113082126A true CN113082126A (en) 2021-07-09

Family

ID=76680713

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110468346.4A Pending CN113082126A (en) 2021-04-28 2021-04-28 Preparation method of dampness-removing itching-relieving lotion

Country Status (1)

Country Link
CN (1) CN113082126A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114099623A (en) * 2021-10-14 2022-03-01 辽宁中医药大学 Dehumidifying and itching-relieving ointment and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1634259A (en) * 2004-10-28 2005-07-06 重庆希尔安药业有限公司 Lotion containing capillary artemisia and wild chrysanthemum flower and its preparing method
CN1768812A (en) * 2005-10-24 2006-05-10 高欲林 Medicinal composition for removing dampness to relieve itching and its preparation method and uses
CN101862400A (en) * 2010-04-09 2010-10-20 成都天宇联盟医药科技有限责任公司 Dehumidifying itching-relieving gels and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1634259A (en) * 2004-10-28 2005-07-06 重庆希尔安药业有限公司 Lotion containing capillary artemisia and wild chrysanthemum flower and its preparing method
CN1768812A (en) * 2005-10-24 2006-05-10 高欲林 Medicinal composition for removing dampness to relieve itching and its preparation method and uses
CN101862400A (en) * 2010-04-09 2010-10-20 成都天宇联盟医药科技有限责任公司 Dehumidifying itching-relieving gels and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114099623A (en) * 2021-10-14 2022-03-01 辽宁中医药大学 Dehumidifying and itching-relieving ointment and preparation method thereof

Similar Documents

Publication Publication Date Title
CN104306908A (en) Health-care composition for preventing respiratory system diseases caused by haze, and preparation method thereof
CN102302553A (en) Extraction method of key components of Chinese magnoliavine fruit medicament
CN101954002A (en) Traditional Chinese instant herbal medicine for loosing weight
CN101519408A (en) Method for producing glabridin from glycyrrhiza residue
CN113082126A (en) Preparation method of dampness-removing itching-relieving lotion
CN105311069A (en) Traditional Chinese medicine composition for reducing blood lipid and protecting livers
CN1857610A (en) Health article containing lindera leaf extract and its preparing method
CN101401843B (en) Extracting method for active principle of traditional Chinese medicine red sage root
CN101361911A (en) External skin composition with wrinkle-dispelling function and production method thereof
CN102048910A (en) Honeysuckle oral liquid
CN104922442A (en) Traditional Chinese medicine for treating fever
CN104771702A (en) Preparation method of traditional Chinese medicine composition for treating fatty liver and fat hepatitis
CN102178710A (en) Method for preparing fissistigma total flavonoids and fissistigma total alkali
CN102151240A (en) Traditional Chinese medicine bath cream and preparation method thereof
CN102343021A (en) New process method for preparing Guifudihuang capsule
CN112043763A (en) Herbal quick-acting dermatitis eczema cream
CN100417410C (en) Medicine for treating gastrointestinal summer damp cold and preparing method thereof
CN105148240A (en) Medicinal preparation used for treating chronic cardiac failure
CN101156892A (en) A preparation method of active component composition of antineoplastic improving phylactic power
CN105434264A (en) Motherwort-herb toothpaste
CN101658627A (en) Granules for tranquillization
CN1238944A (en) Process for preparing powdered bath lotion from liquid one of natural plant
CN108524663A (en) A kind of composition for alleviating pain and detumescence and preparation method thereof and preparation
CN114796316B (en) Traditional Chinese medicine composition for preventing alopecia and promoting hair growth, preparation method and application
CN105561178A (en) Method for preparing easing oral liquid

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20210709

RJ01 Rejection of invention patent application after publication