CN113081931A - Cutin repair essence - Google Patents
Cutin repair essence Download PDFInfo
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- CN113081931A CN113081931A CN202110320591.0A CN202110320591A CN113081931A CN 113081931 A CN113081931 A CN 113081931A CN 202110320591 A CN202110320591 A CN 202110320591A CN 113081931 A CN113081931 A CN 113081931A
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- parts
- extract
- essence
- dendrobium nobile
- salvia miltiorrhiza
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- 230000008439 repair process Effects 0.000 title claims abstract description 29
- 229920000832 Cutin Polymers 0.000 title claims abstract description 20
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims abstract description 36
- 240000004638 Dendrobium nobile Species 0.000 claims abstract description 27
- 241000219357 Cactaceae Species 0.000 claims abstract description 24
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 claims abstract description 23
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 19
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims abstract description 18
- 239000001140 aloe barbadensis leaf extract Substances 0.000 claims abstract description 18
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 claims abstract description 18
- 229940101267 panthenol Drugs 0.000 claims abstract description 18
- 235000020957 pantothenol Nutrition 0.000 claims abstract description 18
- 239000011619 pantothenol Substances 0.000 claims abstract description 18
- 229940032094 squalane Drugs 0.000 claims abstract description 18
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims abstract description 17
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims abstract description 17
- 239000008367 deionised water Substances 0.000 claims abstract description 17
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 17
- 229920002674 hyaluronan Polymers 0.000 claims abstract description 17
- 229960003160 hyaluronic acid Drugs 0.000 claims abstract description 17
- 239000002994 raw material Substances 0.000 claims abstract description 13
- 238000002360 preparation method Methods 0.000 claims abstract description 8
- 241000304195 Salvia miltiorrhiza Species 0.000 claims abstract 7
- 238000003756 stirring Methods 0.000 claims description 30
- 238000002156 mixing Methods 0.000 claims description 22
- 239000000203 mixture Substances 0.000 claims description 19
- 239000000243 solution Substances 0.000 claims description 18
- 239000011259 mixed solution Substances 0.000 claims description 17
- 238000000034 method Methods 0.000 claims description 15
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 12
- 241000196324 Embryophyta Species 0.000 claims description 9
- 241000246044 Sophora flavescens Species 0.000 claims description 8
- 235000002961 Aloe barbadensis Nutrition 0.000 claims description 6
- 235000011399 aloe vera Nutrition 0.000 claims description 6
- 238000001816 cooling Methods 0.000 claims description 6
- 238000004806 packaging method and process Methods 0.000 claims description 6
- 238000002791 soaking Methods 0.000 claims description 6
- 238000003860 storage Methods 0.000 claims description 6
- 238000005303 weighing Methods 0.000 claims description 6
- 210000004911 serous fluid Anatomy 0.000 claims description 2
- 102000011782 Keratins Human genes 0.000 claims 6
- 108010076876 Keratins Proteins 0.000 claims 6
- 244000144927 Aloe barbadensis Species 0.000 claims 1
- 229940096857 opUNTia ficus-indica extract Drugs 0.000 claims 1
- 230000003020 moisturizing effect Effects 0.000 abstract description 11
- 208000003251 Pruritus Diseases 0.000 abstract description 5
- 230000008901 benefit Effects 0.000 abstract description 4
- 230000003266 anti-allergic effect Effects 0.000 abstract description 3
- 230000035876 healing Effects 0.000 abstract description 3
- 230000003647 oxidation Effects 0.000 abstract description 3
- 238000007254 oxidation reaction Methods 0.000 abstract description 3
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 230000007803 itching Effects 0.000 abstract 1
- 238000004904 shortening Methods 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 21
- 244000132619 red sage Species 0.000 description 16
- 230000000694 effects Effects 0.000 description 9
- 238000010438 heat treatment Methods 0.000 description 8
- 241000283973 Oryctolagus cuniculus Species 0.000 description 7
- 239000006210 lotion Substances 0.000 description 7
- 244000186892 Aloe vera Species 0.000 description 5
- 210000002615 epidermis Anatomy 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 230000007794 irritation Effects 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 3
- 230000003712 anti-aging effect Effects 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000002085 irritant Substances 0.000 description 2
- 231100000021 irritant Toxicity 0.000 description 2
- 230000037307 sensitive skin Effects 0.000 description 2
- 102000010637 Aquaporins Human genes 0.000 description 1
- 108010063290 Aquaporins Proteins 0.000 description 1
- 241001523681 Dendrobium Species 0.000 description 1
- 102100028314 Filaggrin Human genes 0.000 description 1
- 108700041153 Filaggrin Proteins Proteins 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 240000007164 Salvia officinalis Species 0.000 description 1
- 206010040844 Skin exfoliation Diseases 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 241000219784 Sophora Species 0.000 description 1
- 102000000591 Tight Junction Proteins Human genes 0.000 description 1
- 108010002321 Tight Junction Proteins Proteins 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 210000000270 basal cell Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 239000004568 cement Substances 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000035618 desquamation Effects 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000036074 healthy skin Effects 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 235000005412 red sage Nutrition 0.000 description 1
- 239000004576 sand Substances 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 230000037380 skin damage Effects 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 210000000434 stratum corneum Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Gerontology & Geriatric Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to the technical field of essence preparation, and discloses a cutin repairing essence which comprises the following raw materials in parts by weight: the dendrobium nobile lindl extract is 0.02-0.1 part of dendrobium nobile lindl extract, 0.1-0.2 part of salvia miltiorrhiza extract, 1-2 parts of squalane, 0.1-0.25 part of hyaluronic acid, 3-5 parts of butanediol, 0.5-1.5 parts of panthenol, 0.5-1.5 parts of cactus extract, 0.05-0.3 part of radix sophorae flavescentis extract, 5-15 parts of aloe vera leaf juice and 80-100 parts of deionized water. The repair essence disclosed by the invention has excellent oxidation resistance, repairability and high anti-allergy itching relieving performance, can be used for deeply moisturizing skin, is good in moisturizing effect, can also be used for shortening the healing period of the skin, is low in production cost, is convenient to popularize and use, and is high in economic benefit.
Description
Technical Field
The invention relates to the technical field of essence preparation, and particularly relates to cutin repairing essence.
Background
The skin is the largest organ that covers the surface of the human body, and the basic elements of healthy skin are smooth, full and elastic. The stratum corneum, which is the outermost part of the epidermis, is mainly composed of 10 to 20 flat dead cells without nuclei, and is directly in contact with the external environment, and is easily damaged by various factors such as oxidation, dryness, ultraviolet rays, and the like, and is sensitive and irritated by long-term skin damage.
The repairing essence in the market is various, but the repairing effect is not ideal, sensitive skin with damaged cuticle is easy to irritate, in addition, the existing repairing essence cannot play an effective moisturizing role on the skin, moisturizing ingredients usually only stay on the surface of the skin and cannot permeate into the deep layer of the skin to moisturize, and therefore the cutin repairing essence is provided.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides the cutin repair essence lotion which has the advantages of deep moisturizing of skin, good repair effect, safety and no stimulation, and solves the problems that the repair effect of the repair essence lotion in the prior art is not ideal, and sensitive skin with damaged cuticle is easily stimulated.
(II) technical scheme
In order to realize the purposes of quantitatively adding cement and sand and stone and automatically adding water, the invention provides the following technical scheme: the cutin repair essence comprises the following raw materials in parts by weight: the dendrobium nobile lindl extract is 0.02-0.1 part of dendrobium nobile lindl extract, 0.1-0.2 part of salvia miltiorrhiza extract, 1-2 parts of squalane, 0.1-0.25 part of hyaluronic acid, 3-5 parts of butanediol, 0.5-1.5 parts of panthenol, 0.5-1.5 parts of cactus extract, 0.05-0.3 part of radix sophorae flavescentis extract, 5-15 parts of aloe vera leaf juice and 80-100 parts of deionized water.
Preferably, the feed comprises the following raw materials in parts by weight: 0.05 part of dendrobium nobile extract, 0.12 part of salvia miltiorrhiza extract, 1.4 parts of squalane, 0.2 part of hyaluronic acid, 4 parts of butanediol, 1.2 parts of panthenol, 0.45 part of cactus extract, 0.1 part of sophora flavescens extract, 10 parts of aloe barbadensis leaf juice and 90 parts of deionized water.
Preferably, the feed comprises the following raw materials in parts by weight: 0.06 part of dendrobium nobile extract, 0.15 part of salvia miltiorrhiza extract, 1.5 parts of squalane, 0.2 part of hyaluronic acid, 4.5 parts of butanediol, 1.3 parts of panthenol, 0.4 part of cactus extract, 0.07 part of sophora flavescens extract, 12 parts of aloe barbadensis leaf juice and 95 parts of deionized water.
Further, the preparation method of the cutin repair essence comprises the following steps:
s1, preparing clean dendrobium nobile, salvia miltiorrhiza, cactus, radix sophorae flavescentis and aloe barbadensis leaves, respectively crushing, soaking and homogenizing the plants to obtain serous fluid, and respectively extracting dendrobium nobile extract, salvia miltiorrhiza extract, cactus extract, radix sophorae flavescentis extract and aloe barbadensis leaf juice;
s2, stirring and mixing the extracting solution in the step S1 according to the weight part to obtain an extracting solution mixture;
s3, weighing squalane, hyaluronic acid, butanediol, panthenol and deionized water according to a proportion, uniformly stirring to obtain a mixed solution, pouring the mixture of the extracting solutions in the S2 into the mixed solution, and continuously stirring until the mixture is uniformly mixed to obtain essence;
and S4, cooling the essence to room temperature, bottling, packaging and warehousing for storage.
Further, in step S1, the dendrobium nobile lindl extract, the salvia miltiorrhiza extract, the cactus extract and the sophora flavescens extract are extracted by an ultrasonic-assisted ethanol method.
Furthermore, when the plants in the step S1 are crushed, the plants need to be sieved by a sieve of 60-100 meshes.
Further, in step S2, the extracting solution is heated to 70-90 ℃ at a speed of 600-800 r/min when being mixed.
Further, in step S3, the temperature of the mixed solution is 60-75 ℃ while stirring, the stirring speed is 800-1000 r/min, after complete mixing, the temperature is raised to 80-90 ℃, then the mixture of the extracting solutions is slowly poured in, and the mixture is stirred at 900-1200 r/min until complete mixing.
(III) advantageous effects
Compared with the prior art, the invention provides the cutin repair essence which has the following beneficial effects:
1. the dendrobium nobile extract in the raw materials of the invention can promote the expression of aquaporin, filaggrin and tight junction protein, has good moisturizing capability, also has obvious anti-aging and anti-aging effects, moistens the skin, can enhance the differentiation and hydration activity of the epidermis, possibly enhances the function of the epidermis for resisting skin aging, nourishes the skin deeper, has the anti-allergy, itching-relieving and repairing effects on the skin by mutually matching the cactus extract, the radix sophorae flavescentis extract and panthenol, can promote the proliferation of skin basal cells, open skin pores, promote blood microcirculation, promote the metabolism of cells and help to repair damaged cells by adding squalane in addition to further increasing the anti-oxidation function of the essence, and compared with the existing repairing essence, obviously has better oxidation resistance, repairing property, high anti-allergy and itching-relieving property;
2. the essence disclosed by the invention is safe and non-irritant, can be used for a long time, is used for repairing the horny layer of the skin and deeply replenishing water to the skin, has a good repairing effect, can obviously shorten the healing period of a patient with symptoms of dryness, desquamation, red swelling, pruritus and the like of the skin, and has a good healing effect;
3. the essence disclosed by the invention is simple in raw material acquisition, simple and easy to operate in the processing process, low in production cost, convenient to popularize and use and high in economic benefit.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example one
The cutin repair essence comprises the following raw materials in parts by weight: is prepared from dendrobium stem extract 0.02 parts, red sage root extract 0.1 parts, squalane 1 parts, hyaluronic acid 0.1 parts, butanediol 3 parts, panthenol 0.5 parts, cactus extract 0.5 parts, flavescent sophora root extract 0.05 parts, aloe barbadensis leaf juice 5 parts, and deionized water 80 parts.
The preparation method of the cutin repair essence comprises the following steps:
s1, preparing clean dendrobium nobile, salvia miltiorrhiza, cactus, radix sophorae flavescentis and aloe barbadensis leaf, crushing, soaking and homogenizing the plants respectively to obtain pulp, and extracting dendrobium nobile extract, salvia miltiorrhiza extract, cactus extract, radix sophorae flavescentis extract and aloe barbadensis leaf juice respectively by adopting an ultrasonic-assisted ethanol method;
s2, stirring and mixing the extracting solution in the step S1 into an extracting solution mixture according to the parts by weight, and heating to 70 ℃ at a speed of 700r/min during mixing;
s3, weighing squalane, hyaluronic acid, butanediol, panthenol and deionized water according to a proportion, uniformly stirring to obtain a mixed solution, stirring the mixed solution at the temperature of 70 ℃ at the stirring speed of 900r/min, heating to 80 ℃ after complete mixing, slowly pouring the mixed solution into the extract mixture in S2, and stirring at the speed of 1000r/min until complete mixing to obtain essence lotion;
and S4, cooling the essence to room temperature, bottling, packaging and warehousing for storage.
Example two
The cutin repair essence comprises the following raw materials in parts by weight: 0.05 part of dendrobium nobile extract, 0.12 part of salvia miltiorrhiza extract, 1.4 parts of squalane, 0.2 part of hyaluronic acid, 4 parts of butanediol, 1.2 parts of panthenol, 0.45 part of cactus extract, 0.1 part of sophora flavescens extract, 10 parts of aloe barbadensis leaf juice and 90 parts of deionized water.
The preparation method of the cutin repair essence comprises the following steps:
s1, preparing clean dendrobium nobile, salvia miltiorrhiza, cactus, radix sophorae flavescentis and aloe barbadensis leaf, crushing, soaking and homogenizing the plants respectively to obtain pulp, and extracting dendrobium nobile extract, salvia miltiorrhiza extract, cactus extract, radix sophorae flavescentis extract and aloe barbadensis leaf juice respectively by adopting an ultrasonic-assisted ethanol method;
s2, stirring and mixing the extracting solution in the step S1 into an extracting solution mixture according to the parts by weight, and heating to 75 ℃ at a speed of 700r/min during mixing;
s3, weighing squalane, hyaluronic acid, butanediol, panthenol and deionized water according to a proportion, uniformly stirring to obtain a mixed solution, stirring the mixed solution at the temperature of 65 ℃ at the stirring speed of 800r/min, heating to 85 ℃ after complete mixing, slowly pouring the mixed solution into the extract mixture in S2, and stirring at the speed of 900r/min until complete mixing to obtain essence lotion;
and S4, cooling the essence to room temperature, bottling, packaging and warehousing for storage.
EXAMPLE III
The cutin repair essence comprises the following raw materials in parts by weight: 0.06 part of dendrobium nobile extract, 0.15 part of salvia miltiorrhiza extract, 1.5 parts of squalane, 0.2 part of hyaluronic acid, 4.5 parts of butanediol, 1.3 parts of panthenol, 0.4 part of cactus extract, 0.07 part of sophora flavescens extract, 12 parts of aloe barbadensis leaf juice and 95 parts of deionized water.
The preparation method of the cutin repair essence comprises the following steps:
s1, preparing clean dendrobium nobile, salvia miltiorrhiza, cactus, radix sophorae flavescentis and aloe barbadensis leaf, crushing, soaking and homogenizing the plants respectively to obtain pulp, and extracting dendrobium nobile extract, salvia miltiorrhiza extract, cactus extract, radix sophorae flavescentis extract and aloe barbadensis leaf juice respectively by adopting an ultrasonic-assisted ethanol method;
s2, stirring and mixing the extracting solution in the step S1 into an extracting solution mixture according to the parts by weight, and heating to 85 ℃ at the speed of 700r/min during mixing;
s3, weighing squalane, hyaluronic acid, butanediol, panthenol and deionized water according to a proportion, uniformly stirring to obtain a mixed solution, stirring the mixed solution at the temperature of 70 ℃ at the stirring speed of 1000r/min, heating to 85 ℃ after complete mixing, slowly pouring the mixed solution into the extract mixture in S2, and stirring at the speed of 1100r/min until complete mixing to obtain essence liquid;
and S4, cooling the essence to room temperature, bottling, packaging and warehousing for storage.
Example four
The cutin repair essence comprises the following raw materials in parts by weight: is prepared from herba Dendrobii extract 0.1 parts, Saviae Miltiorrhizae radix extract 0.2 parts, squalane 2 parts, hyaluronic acid 0.25 parts, butanediol 5 parts, panthenol 1.5 parts, radix et caulis Opuntiae Dillenii extract 1.5 parts, radix Sophorae Flavescentis extract 0.3 parts, Aloe Barbadensis leaf juice 15 parts, and deionized water 100 parts.
The preparation method of the cutin repair essence comprises the following steps:
s1, preparing clean dendrobium nobile, salvia miltiorrhiza, cactus, radix sophorae flavescentis and aloe barbadensis leaf, crushing, soaking and homogenizing the plants respectively to obtain pulp, and extracting dendrobium nobile extract, salvia miltiorrhiza extract, cactus extract, radix sophorae flavescentis extract and aloe barbadensis leaf juice respectively by adopting an ultrasonic-assisted ethanol method;
s2, stirring and mixing the extracting solution in the step S1 into an extracting solution mixture according to the parts by weight, and heating to 90 ℃ at a speed of 800r/min during mixing;
s3, weighing squalane, hyaluronic acid, butanediol, panthenol and deionized water according to a proportion, uniformly stirring to obtain a mixed solution, stirring the mixed solution at 75 ℃ at a stirring speed of 1000r/min, heating to 90 ℃ after complete mixing, slowly pouring the mixture of the extracting solutions in S2, and stirring at 1200r/min until complete mixing to obtain essence lotion;
and S4, cooling the essence to room temperature, bottling, packaging and warehousing for storage.
Taking the essence lotions prepared in the four groups of examples to carry out allergy and irritation tests, taking four rabbits for the test, shaving the same positions on the back two sides of the rabbits for hair shaving treatment, ensuring that the epidermis is not damaged in the hair shaving process, measuring the moisture of the skin on the two sides of each rabbit before the test, marking the initial moisture percentage of the skin on the two sides as A1 and A2, respectively smearing the essence lotions in the four groups of examples on one side of the four rabbits, marking the skin on the other side of the four rabbits as a blank control, marking the skin according to the skin irritation reaction marking standard in the cosmetic hygiene Specification, finishing the irritation reaction after 4 hours, and testing the moisture percentage of the skin on the two sides of each rabbit as B1 and B2 after the completion, and obtaining the following table:
in the above table, the concept of no irritation is that the rabbit epidermis is red and swollen with irritation.
As can be clearly seen from the above table, the essence prepared by the invention is safe and non-irritant, and has good moisturizing and moisturizing effects on skin, wherein the moisture content is increased most in the second embodiment, which proves that the essence prepared by the invention can improve the moisturizing and moisturizing effects on skin, and the essence prepared by the formula and the method in the second embodiment has the best moisturizing effect.
In the dermatology department of hospitals, 15 patients with dry, desquamating and red, swollen and pruritus symptoms are selected, after consent is obtained, the affected parts of the patients are divided into two areas with similar sizes and are respectively marked as C1 and C2, the essence prepared in the second embodiment and the existing repair medicine with better effect are respectively smeared in C1 and C2, the two areas are respectively smeared on the affected parts once in the morning and at night, the repair time of the C1 and C2 areas of the skin of each patient is recorded, and the results are as follows:
compared with the repair medicines in the prior art, the repair essence disclosed by the invention has the advantages that the obvious drug effect is better, the cure period of a patient is shortened, the patient with serious symptoms can be treated timely, and the essence disclosed by the invention still has an obvious repair effect.
It is to be noted that the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (8)
1. The cutin repair essence is characterized by comprising the following raw materials in parts by weight: the dendrobium nobile lindl extract is 0.02-0.1 part of dendrobium nobile lindl extract, 0.1-0.2 part of salvia miltiorrhiza extract, 1-2 parts of squalane, 0.1-0.25 part of hyaluronic acid, 3-5 parts of butanediol, 0.5-1.5 parts of panthenol, 0.5-1.5 parts of cactus extract, 0.05-0.3 part of radix sophorae flavescentis extract, 5-15 parts of aloe vera leaf juice and 80-100 parts of deionized water.
2. The cutin repair essence according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 0.05 part of dendrobium nobile extract, 0.12 part of salvia miltiorrhiza extract, 1.4 parts of squalane, 0.2 part of hyaluronic acid, 4 parts of butanediol, 1.2 parts of panthenol, 0.45 part of cactus extract, 0.1 part of sophora flavescens extract, 10 parts of aloe barbadensis leaf juice and 90 parts of deionized water.
3. The cutin repair essence according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 0.06 part of dendrobium nobile extract, 0.15 part of salvia miltiorrhiza extract, 1.5 parts of squalane, 0.2 part of hyaluronic acid, 4.5 parts of butanediol, 1.3 parts of panthenol, 0.4 part of cactus extract, 0.07 part of sophora flavescens extract, 12 parts of aloe barbadensis leaf juice and 95 parts of deionized water.
4. The keratin repair essence according to claim 1, wherein the preparation method of the keratin repair essence comprises:
s1, preparing clean dendrobium nobile, salvia miltiorrhiza, cactus, radix sophorae flavescentis and aloe barbadensis leaves, respectively crushing, soaking and homogenizing the plants to obtain serous fluid, and respectively extracting dendrobium nobile extract, salvia miltiorrhiza extract, cactus extract, radix sophorae flavescentis extract and aloe barbadensis leaf juice;
s2, stirring and mixing the extracting solution in the step S1 according to the weight part to obtain an extracting solution mixture;
s3, weighing squalane, hyaluronic acid, butanediol, panthenol and deionized water according to a proportion, uniformly stirring to obtain a mixed solution, pouring the mixture of the extracting solutions in the S2 into the mixed solution, and continuously stirring until the mixture is uniformly mixed to obtain essence;
and S4, cooling the essence to room temperature, bottling, packaging and warehousing for storage.
5. The essence for repairing keratin according to claim 4, wherein in step S1, the Dendrobium nobile extract, the Salvia miltiorrhiza extract, the Opuntia ficus-indica extract, the Sophora flavescens extract and the Aloe barbadensis leaf juice are extracted by an ultrasonic-assisted ethanol method.
6. The essence for repairing keratin according to claim 4, wherein the plant in step S1 is ground with a 60-100 mesh sieve.
7. The essence for repairing keratin according to claim 4, wherein in step S2, the extract is heated to 70-90 ℃ at a speed of 600-800 r/min.
8. The essence for repairing keratin according to claim 4, wherein in step S3, the temperature of the mixed solution is 60-75 ℃ while stirring, the stirring speed is 800-1000 r/min, after complete mixing, the temperature is raised to 80-90 ℃, then the extract mixture is slowly poured into the mixture, and the mixture is stirred at 900-1200 r/min until complete mixing.
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