CN113015555B - 缓泻用片剂 - Google Patents

缓泻用片剂 Download PDF

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Publication number
CN113015555B
CN113015555B CN201980074733.0A CN201980074733A CN113015555B CN 113015555 B CN113015555 B CN 113015555B CN 201980074733 A CN201980074733 A CN 201980074733A CN 113015555 B CN113015555 B CN 113015555B
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CN
China
Prior art keywords
tablet
magnesium oxide
volume
disintegrant
particle diameter
Prior art date
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Active
Application number
CN201980074733.0A
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English (en)
Chinese (zh)
Other versions
CN113015555A (zh
Inventor
服部笃之
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Storas Holding Co
Original Assignee
Storas Holding Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Storas Holding Co filed Critical Storas Holding Co
Publication of CN113015555A publication Critical patent/CN113015555A/zh
Application granted granted Critical
Publication of CN113015555B publication Critical patent/CN113015555B/zh
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08—Oxides; Hydroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201980074733.0A 2018-11-16 2019-11-15 缓泻用片剂 Active CN113015555B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018215180 2018-11-16
JP2018-215180 2018-11-16
PCT/JP2019/044876 WO2020101016A1 (ja) 2018-11-16 2019-11-15 緩下用錠剤

Publications (2)

Publication Number Publication Date
CN113015555A CN113015555A (zh) 2021-06-22
CN113015555B true CN113015555B (zh) 2023-05-30

Family

ID=70731929

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980074733.0A Active CN113015555B (zh) 2018-11-16 2019-11-15 缓泻用片剂

Country Status (7)

Country Link
US (1) US12053549B2 (enExample)
EP (1) EP3881897A4 (enExample)
JP (3) JP7111389B2 (enExample)
KR (1) KR102682646B1 (enExample)
CN (1) CN113015555B (enExample)
TW (1) TWI724629B (enExample)
WO (1) WO2020101016A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4378467A4 (en) * 2021-07-30 2025-07-30 Setolas Holdings Inc PHARMACEUTICAL COMPOSITION CONTAINING MAGNESIUM OXIDE FOR THE TREATMENT OF CHRONIC FUNCTIONAL CONSTIPATION IN PEDIATRICS
JP7340572B2 (ja) * 2021-08-20 2023-09-07 セトラスホールディングス株式会社 酸化マグネシウム錠剤
CN115487160A (zh) * 2022-09-27 2022-12-20 威海百合生物技术股份有限公司 一种氧化镁片及其制备方法
CN120036483A (zh) * 2025-01-06 2025-05-27 仙乐健康科技股份有限公司 一种微胶囊、片剂及其制备方法和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006022060A (ja) * 2004-07-09 2006-01-26 Kyowa Chem Ind Co Ltd 制酸・緩下用水分散液およびそのための錠剤
CN102481315A (zh) * 2009-09-08 2012-05-30 协和化学工业株式会社 抗酸缓泻用片剂

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8710965D0 (en) * 1987-05-08 1987-06-10 Smith Kline French Lab Pharmaceutical compositions
JP4015485B2 (ja) 2001-08-27 2007-11-28 協和化学工業株式会社 制酸・緩下用錠剤
CN1262278C (zh) * 2001-08-27 2006-07-05 协和化学工业株式会社 抗酸·缓泻用片剂
US20090186081A1 (en) 2006-01-05 2009-07-23 Lifecycle Pharma A/S Disintegrating Loadable Tablets
BRPI0811303A2 (pt) 2007-05-08 2015-01-27 Hercules Inc Formulação de comprimido de desintegranção rápida robusta
MX2009012210A (es) 2007-05-11 2010-01-26 Aloebiotics Res Labs Inc Preparacion de aloe para el mejoramiento de la piel.
JP2010265208A (ja) 2009-05-14 2010-11-25 Kyowa Chem Ind Co Ltd 膵臓機能強化乃至活性化用複合酸化マグネシウム粒子
JP2014224080A (ja) * 2013-05-17 2014-12-04 協和化学工業株式会社 大腸の検査または手術のための処置剤

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006022060A (ja) * 2004-07-09 2006-01-26 Kyowa Chem Ind Co Ltd 制酸・緩下用水分散液およびそのための錠剤
CN102481315A (zh) * 2009-09-08 2012-05-30 协和化学工业株式会社 抗酸缓泻用片剂

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
谢秀琼.崩解剂筛选及优化.《中药新制剂开发与应用》.人民卫生出版社,2006, *

Also Published As

Publication number Publication date
JP7657275B2 (ja) 2025-04-04
WO2020101016A1 (ja) 2020-05-22
TWI724629B (zh) 2021-04-11
US12053549B2 (en) 2024-08-06
JP7360503B2 (ja) 2023-10-12
EP3881897A4 (en) 2022-08-10
JP7111389B2 (ja) 2022-08-02
KR102682646B1 (ko) 2024-07-09
EP3881897A1 (en) 2021-09-22
KR20210076066A (ko) 2021-06-23
JP2022105754A (ja) 2022-07-14
US20210401754A1 (en) 2021-12-30
JPWO2020101016A1 (ja) 2021-09-02
TW202031249A (zh) 2020-09-01
JP2023165999A (ja) 2023-11-17
CN113015555A (zh) 2021-06-22

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Applicant before: KYOWA CHEMICAL INDUSTRY Co.,Ltd.

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