CN112999344A - E1e2 hcv疫苗及使用方法 - Google Patents

E1e2 hcv疫苗及使用方法 Download PDF

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Publication number
CN112999344A
CN112999344A CN202110252076.3A CN202110252076A CN112999344A CN 112999344 A CN112999344 A CN 112999344A CN 202110252076 A CN202110252076 A CN 202110252076A CN 112999344 A CN112999344 A CN 112999344A
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China
Prior art keywords
polypeptide
gly
leu
pro
val
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Pending
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CN202110252076.3A
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English (en)
Chinese (zh)
Inventor
M·霍顿
D·霍克曼
J·L·劳
M·洛根
L·D·泰瑞尔
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Alberta Board Of Directors, University of
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Alberta Board Of Directors, University of
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Publication of CN112999344A publication Critical patent/CN112999344A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN202110252076.3A 2013-05-15 2014-05-15 E1e2 hcv疫苗及使用方法 Pending CN112999344A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361823712P 2013-05-15 2013-05-15
US61/823,712 2013-05-15
US201361887229P 2013-10-04 2013-10-04
US61/887,229 2013-10-04
CN201480027001.3A CN105263517B (zh) 2013-05-15 2014-05-15 E1e2hcv疫苗及使用方法

Related Parent Applications (1)

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CN201480027001.3A Division CN105263517B (zh) 2013-05-15 2014-05-15 E1e2hcv疫苗及使用方法

Publications (1)

Publication Number Publication Date
CN112999344A true CN112999344A (zh) 2021-06-22

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CN202110252076.3A Pending CN112999344A (zh) 2013-05-15 2014-05-15 E1e2 hcv疫苗及使用方法

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Country Status (8)

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US (3) US20210145963A9 (enExample)
EP (2) EP3689375A1 (enExample)
JP (5) JP2016520077A (enExample)
CN (2) CN105263517B (enExample)
AU (3) AU2014385320B2 (enExample)
CA (1) CA2909586C (enExample)
CL (1) CL2015003333A1 (enExample)
WO (1) WO2015132619A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3359577A4 (en) * 2015-10-08 2019-04-17 The Governors of the University of Alberta HEPATITIS C-VIRUS E1 / E2 HETERODIMERS AND METHOD FOR THE PRODUCTION THEREOF
WO2018055535A2 (en) * 2016-09-21 2018-03-29 The Governors Of The University Of Alberta Hepatitis c virus immunogenic compositions and methods of use thereof
WO2018068132A1 (en) * 2016-10-11 2018-04-19 The Governors Of The University Of Alberta Hepatitis c virus immunogenic compositions comprising as an adjuvant a cyclic dinucleotide or an archaeosome and methods of use thereof
EP3765075A4 (en) 2018-03-16 2021-12-08 The Governors of the University of Alberta PEPTIDIC COMPOSITIONS OF THE HEPATITIS C VIRUS AND THEIR USE PROCEDURES

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WO2007041432A2 (en) * 2005-09-30 2007-04-12 Novartis Vaccines And Diagnostics, Inc. Cross-neutralization of hcv with recombinant proteins
US20090258033A1 (en) * 2001-06-29 2009-10-15 Chiron Corporation HCV E1E2 vaccine compositions

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US20090258033A1 (en) * 2001-06-29 2009-10-15 Chiron Corporation HCV E1E2 vaccine compositions
WO2007041432A2 (en) * 2005-09-30 2007-04-12 Novartis Vaccines And Diagnostics, Inc. Cross-neutralization of hcv with recombinant proteins

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Also Published As

Publication number Publication date
EP2996718B1 (en) 2020-01-15
CA2909586A1 (en) 2015-09-11
JP2016520077A (ja) 2016-07-11
JP2021059596A (ja) 2021-04-15
US20210145963A9 (en) 2021-05-20
JP2022172244A (ja) 2022-11-15
HK1216395A1 (en) 2016-11-11
CL2015003333A1 (es) 2016-09-30
AU2014385320A1 (en) 2015-11-12
JP2019142962A (ja) 2019-08-29
AU2014385320B2 (en) 2019-10-10
US20230098265A1 (en) 2023-03-30
US20160067332A1 (en) 2016-03-10
CN105263517B (zh) 2021-03-26
AU2020200216A1 (en) 2020-02-06
US20240316186A1 (en) 2024-09-26
AU2022200747A1 (en) 2022-02-24
WO2015132619A1 (en) 2015-09-11
EP3689375A1 (en) 2020-08-05
EP2996718A4 (en) 2017-06-21
JP2024156917A (ja) 2024-11-06
CA2909586C (en) 2021-08-31
CN105263517A (zh) 2016-01-20
EP2996718A1 (en) 2016-03-23

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Application publication date: 20210622