CN112999277A - Composition for promoting fluid production, tonifying yang and delaying senescence and application thereof - Google Patents

Composition for promoting fluid production, tonifying yang and delaying senescence and application thereof Download PDF

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Publication number
CN112999277A
CN112999277A CN201911351961.6A CN201911351961A CN112999277A CN 112999277 A CN112999277 A CN 112999277A CN 201911351961 A CN201911351961 A CN 201911351961A CN 112999277 A CN112999277 A CN 112999277A
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grass
pounding
composition
tonifying yang
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李守黔
李守跃
周誉
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Guizhou Jinqianguo Biotechnology Co ltd
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Guizhou Jinqianguo Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/074Ganoderma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738Rosa (rose)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
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  • Insects & Arthropods (AREA)
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  • Biochemistry (AREA)
  • Animal Husbandry (AREA)
  • Polymers & Plastics (AREA)
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  • Food Science & Technology (AREA)
  • Medicines Containing Plant Substances (AREA)
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Abstract

The invention belongs to the technical field of medicines, and particularly relates to a composition for promoting the production of body fluid, tonifying yang, enhancing human immunity and delaying senescence and an application thereof, wherein the composition comprises the following substances: 5-100 parts of pounding grass, 5-100 parts of bitter honey, 5-100 parts of rosa roxburghii tratt, 1-30 parts of green lemon and 1-30 parts of lucid ganoderma, and the pounding grass can achieve the function of delaying senility by promoting the production of body fluid and tonifying yang, enhancing the immunity of a human body and improving the physical function.

Description

Composition for promoting fluid production, tonifying yang and delaying senescence and application thereof
Technical Field
The invention belongs to the technical field of medicines, and particularly relates to a composition for promoting the production of body fluid, tonifying yang, enhancing human immunity and delaying senescence and application thereof.
Background
Aging is a progressive process in which the functional activities of the organs of the body gradually decline with age and the storage capacity of the body decreases after the body develops and matures. It is mainly manifested as lassitude, weakness of waist and knees, amnesia, poor appetite, insomnia, short breath, asthenia, alopecia, tooth-shake, cold body and cold limbs.
At present, the aging mechanism is not consistent, and modern medical research considers that the aging mechanism can be related to factors such as in vivo oxidative free radical change, endocrine abnormality, brain injury, protein denaturation and heredity; the researchers of traditional Chinese medicine and pharmacy think that the main causes of human body aging include deficiency due to kidney deficiency, deficiency due to weakness of spleen and stomach, deficiency due to qi stagnation and blood stasis, and the like, and the main clinical manifestations of the human body aging include rapid viscera function, aging and degeneration of external orifices, and the functions of viscera tissues, limbs and bones are declined. In recent years, the research of traditional Chinese medicine on the theory of qi stagnation and blood stasis aging has been increasingly emphasized by Chinese medical researchers, which embodies the dissipation structure theory, namely: the human body is considered to be a dissipation structure, and is a system which keeps self stability in the process of continuously exchanging the material energy with the external environment, when the system is in a stasis state for a long time, effective material energy exchange cannot be carried out to supplement the 'material' required by daily activities of the human body, and then the continuous dissipation of the microscopic materials of the body is caused, and the accumulation of harmful materials causes aging. Modern traditional Chinese medicine research shows that with the increase of age, a human body has blood circulation and microcirculation disturbance, blood stasis is easy to form, qi and blood circulation is blocked, viscera cannot be nourished normally, and the gasification function is impaired; meanwhile, the metabolite is not discharged smoothly, accumulated in the body and poisoned to the body, thereby forming a vicious circle and accelerating aging.
Along with the gradual improvement of the life of people, the health care consciousness of people is gradually enhanced, and in addition, the aging of the society is intensified in recent years, and the market has increasingly vigorous demand for products in the aspects of delaying aging and the like. However, the currently common anti-aging products mainly comprise various precious and fine Chinese medicinal materials and preparations thereof, such as: ginseng royal jelly, ginseng buccal tablets, American ginseng buccal tablets, pole grass 5X and the like, but the preparation has single effect and high price, and the actual anti-aging effect is not obvious.
Based on the above, the inventor takes the traditional Chinese medicine theory as guidance, combines clinical research and medication experience for decades, repeatedly optimizes and adjusts the prescription, and finally obtains the composition from the aspects of promoting the production of body fluid and tonifying yang and enhancing the immunity of the human body.
Disclosure of Invention
The invention aims to solve the technical problem of providing a composition for promoting the production of body fluid, tonifying yang, enhancing the immunity of a human body and delaying senescence.
The invention also aims to solve the other technical problem of providing the application of the composition in the aspects of promoting the production of body fluid, tonifying yang, enhancing the immunity of a human body and delaying senescence.
The specific technical scheme of the invention is as follows:
the invention provides a composition for promoting the production of body fluid, tonifying yang, enhancing human immunity and delaying senescence, which is characterized by comprising the following substances in parts by weight: 5-100 parts of pounding grass, 5-100 parts of bitter honey, 5-100 parts of rosa roxburghii tratt, 1-30 parts of green lemon and 1-30 parts of lucid ganoderma.
Preferably, the composition is characterized by comprising the following materials in parts by weight: 10-80 parts of pounding grass, 10-80 parts of bitter honey, 10-80 parts of rosa roxburghii tratt, 2-20 parts of green lemon and 2-20 parts of lucid ganoderma. Preferably, the composition is characterized by comprising the following materials in parts by weight:
15-50 parts of pounding grass, 15-50 parts of bitter honey, 10-50 parts of rosa roxburghii tratt, 5-20 parts of green lemon and 5-20 parts of lucid ganoderma. The invention provides a preparation method of the composition, which is characterized in that the preparation method of the composition
The method comprises the following steps: taking pounding grass, fructus Rosae Normalis, fructus Citri Limoniae and Ganoderma, pulverizing or slicing, extracting with ethanol, percolating, collecting extractive solution or percolate, adding bitter Mel, mixing, and making into oral preparation; or fermenting or soaking the above medicinal materials or food materials to obtain oral preparation.
Preferably, the oral preparation is a wine, an oral liquid, a tincture and the like.
The invention provides the use of said composition, namely: the application in preparing medicaments, health-care foods and foods for promoting the production of body fluid, tonifying yang, enhancing the immunity of a human body and delaying senescence.
The invention has the beneficial effects that:
the composition is prepared by adopting common medicinal materials and food materials through scientific formula by taking the basic theory of traditional Chinese medicine as guidance, has obvious effect when being used for promoting the secretion of saliva or body fluid and tonifying yang, enhancing the immunity of a human body and delaying senescence, can be widely applied to various people, and meets the requirements of promoting the secretion of saliva or body fluid and tonifying yang, enhancing the immunity of the human body and delaying senescence of people.
The materials used by the composition provided by the invention are all derived from pure natural Chinese herbal medicines or conventional foods, and the composition has the characteristics of wide sources, low price, greenness, health, safety, no toxic or side effect and the like, and is suitable for large-scale popularization and use.
The specific implementation mode is as follows:
the present invention will be described in more detail with reference to examples. It is to be understood that the practice of the invention is not limited to the following examples, and that any variations and/or modifications may be made thereto without departing from the scope of the invention.
In the present invention, all parts and percentages are by weight unless otherwise specified. The methods in the following examples are conventional in the art unless otherwise specified; in the invention, the pounding grass, the roxburgh rose, the green lemon and the lucid ganoderma can be fresh products or dried products.
Example 1: taking 100g of pounding grass, 100g of bitter honey, 60g of rosa roxburghii tratt, 30g of green lemon and 15g of lucid ganoderma, adding 50-degree white spirit which is 5 times of the total weight of the formula, soaking for 30 days, filtering, and collecting liquid medicine to obtain the traditional Chinese medicine.
Example 2: taking back 5g of pounding grass, 10g of rosa roxburghii tratt, 3g of green lemon and 1g of lucid ganoderma, crushing into coarse powder, soaking with 50-degree white spirit, percolating and extracting at the flow rate of 1ml/min, collecting percolate with the weight 2 times that of the formula, adding 5g of bitter honey, and uniformly mixing to obtain the traditional Chinese medicine.
Example 3: taking 40g of pounding grass, 40g of bitter honey, 30g of rosa roxburghii tratt, 15g of green lemon and 10g of lucid ganoderma, adding 50-degree white spirit which is 4 times of the total weight of the formula, soaking for 30 days, filtering, and collecting liquid medicine to obtain the traditional Chinese medicine.
Example 4: taking 30g of pounding grass, 25g of rosa roxburghii tratt, 10g of green lemon and 5g of lucid ganoderma back, crushing into coarse powder, soaking with 50-degree white spirit, percolating and extracting at the flow rate of 3ml/min, collecting 3 times of percolate by weight of the formula, adding 20g of bitter honey, and uniformly mixing to obtain the traditional Chinese medicine.
Example 5: taking back 15g of pounding grass, 10g of rosa roxburghii tratt, 10g of green lemon and 5g of lucid ganoderma, adding water which is 6 times of the total weight of the medicinal materials, soaking for half an hour, extracting for 2 times, filtering for 2 hours each time, combining extracting solutions, adding 10g of bitter honey, and uniformly mixing to obtain the traditional Chinese medicine.
Example 6: taking back 15g of pounding grass, 20g of bitter honey, 15g of rosa roxburghii tratt, 1g of green lemon and 3g of lucid ganoderma, adding water which is 4 times of the total weight of the formula, fermenting in a shade for 30 days, filtering, and collecting fermentation liquor.
Example 7: taking 10kg of pounding grass, 6kg of bitter honey, 6kg of rosa roxburghii tratt, 9kg of green lemon and 3kg of lucid ganoderma, adding 50-degree white spirit which is 5 times of the total weight of the formula, soaking for 30 days, filtering, collecting liquid medicine, and subpackaging into 100 ml/bottle to obtain the traditional Chinese medicine.
Example 8: taking 100kg of pounding grass, 90kg of rosa roxburghii tratt, 30kg of green lemon and 25kg of lucid ganoderma, adding water which is 4 times of the total weight of the medicinal materials, soaking for half an hour, extracting for 2 times, filtering for 2 hours each time, combining extracting solutions, adding 3kg of bitter honey, mixing uniformly, and subpackaging into 100 ml/bottle to obtain the traditional Chinese medicine.
Example 9: taking back 5kg of pounding grass, 3kg of rosa roxburghii tratt, 6kg of green lemon and 6kg of lucid ganoderma, soaking the pounding grass, the rosa roxburghii tratt, the green lemon and the lucid ganoderma overnight in 50-degree white wine, percolating and extracting the mixture at the flow rate of 20ml/min, collecting 3 times of percolate according to the weight of the formula, adding 4kg of bitter honey, mixing the mixture evenly, and subpackaging the mixture into 100 ml/bottle to obtain the Chinese medicinal preparation.
Example 10: taking back 6kg of pounding grass, 6kg of bitter honey, 10kg of rosa roxburghii tratt, 2kg of green lemon and 2kg of lucid ganoderma, adding water which is 4 times of the total weight of the formula, fermenting in shade for 30 days, filtering, collecting fermentation liquor, and subpackaging into 100 ml/bottle to obtain the product.
Example 11: clinical effects of the composition of the present invention
The composition has the effects of promoting the production of body fluid, tonifying yang, enhancing the immunity of a human body and delaying senescence. The clinical study data and data are as follows: 245 cases are selected in total between 5 months in 2013 and 5 months in 2019, and the selection criteria are as follows: the patient showed: lassitude, amnesia, cold limbs, poor appetite, insomnia, weakness of waist and knees, alopecia, tooth shake, short breath, debilitation, etc. The treatment method comprises the following steps: the composition of the invention is taken three times a day, 3 weeks are a treatment course, three treatment courses are observed totally, and other anti-aging medicaments are stopped taking during the administration period. The treatment results are as follows:
(1) the clinical overall curative effect is as follows: 173 cases of significant effect account for 70.61%: 43 effective cases account for 17.55 percent; the number of the invalid 29 cases is 11.84 percent. The total effective rate is 216 cases, which accounts for 88.16%.
(2) The improvement effect on the clinical common aging symptoms is shown in the following table:
Figure BDA0002334738000000041
as shown in the table above, the composition can improve various common clinical symptoms caused by human aging to different degrees, and has obvious effects on improving the physical function of patients, delaying aging and the like.
In conclusion, clinical aging syndrome expedition observation and laboratory data analysis show that the composition disclosed by the invention has a remarkable effect on delaying aging by promoting the secretion of saliva or body fluid and tonifying yang and enhancing the immunity of a human body, and does not have adverse reactions or side effects.

Claims (6)

1. The composition for promoting the production of body fluid, tonifying yang, enhancing human immunity and delaying senescence is characterized by comprising the following substances in parts by weight: 5-100 parts of pounding grass, 5-100 parts of bitter honey, 5-100 parts of rosa roxburghii tratt, 1-30 parts of green lemon and 1-30 parts of lucid ganoderma.
2. The composition according to claim 1, characterized in that it consists of, in parts by weight: 10-80 parts of pounding grass, 10-80 parts of bitter honey, 10-80 parts of rosa roxburghii tratt, 2-20 parts of green lemon and 2-20 parts of lucid ganoderma.
3. The composition according to claim 1, characterized in that it consists of, in parts by weight: 15-50 parts of pounding grass, 15-50 parts of bitter honey, 10-50 parts of rosa roxburghii tratt, 5-20 parts of green lemon and 5-20 parts of lucid ganoderma.
4. A composition according to claims 1 to 3, characterized in that it is prepared by a process comprising: taking pounding grass, fructus Rosae Normalis, fructus Citri Limoniae and Ganoderma, pulverizing or slicing, extracting with ethanol, percolating, collecting extractive solution or percolate, adding bitter Mel, mixing, and making into oral preparation; or fermenting or soaking the above medicinal materials or food materials to obtain oral preparation.
5. The composition of claim 4, wherein the oral formulation is a wine, an oral liquid, or a tincture.
6. The composition according to claims 1-5, for use in the preparation of medicaments, health foods and foods for promoting the production of body fluid, tonifying yang, enhancing immunity and delaying aging.
CN201911351961.6A 2019-12-20 2019-12-25 Composition for promoting fluid production, tonifying yang and delaying senescence and application thereof Pending CN112999277A (en)

Applications Claiming Priority (2)

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CN201911322498 2019-12-20

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102461886A (en) * 2010-11-08 2012-05-23 张娣 Health food for senility delaying, and processing method thereof
CN108949476A (en) * 2018-09-28 2018-12-07 贵州兴贵源酒业有限公司 A kind of thorn pear wine and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102461886A (en) * 2010-11-08 2012-05-23 张娣 Health food for senility delaying, and processing method thereof
CN108949476A (en) * 2018-09-28 2018-12-07 贵州兴贵源酒业有限公司 A kind of thorn pear wine and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
吴敏: "四大解腻排毒饮品大推荐", 《肉类工业》 *

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Application publication date: 20210622