CN112998150A - Feed additive for improving overfeeding of piglets, feed and additive preparation method - Google Patents

Feed additive for improving overfeeding of piglets, feed and additive preparation method Download PDF

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CN112998150A
CN112998150A CN202110401698.8A CN202110401698A CN112998150A CN 112998150 A CN112998150 A CN 112998150A CN 202110401698 A CN202110401698 A CN 202110401698A CN 112998150 A CN112998150 A CN 112998150A
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overfeeding
feed
piglets
feed additive
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龚俊勇
吴广兵
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A23K10/37Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/105Aliphatic or alicyclic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/111Aromatic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/163Sugars; Polysaccharides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/189Enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K40/00Shaping or working-up of animal feeding-stuffs
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

Abstract

The invention provides a feed additive for improving the overfeeding of piglets, a feed and a preparation method of the additive, wherein the feed additive comprises the following components in percentage by weight: 5-10% of plant extract; 1-3% of compound acidifier; 3-8% of mannan oligosaccharide; 1-3% of complex enzyme preparation; the balance being carriers. The plant extract maintains the microecological balance of the flora in the digestive tract by bacteriostasis, antibiosis and selective inhibition on bacteria, so as to protect the health of the intestinal tract, can resist the erosion of gastric acid and cause the loss and exhaustion of pathogenic bacteria energy through the synergistic action of the plant extract and a compound acidifier, can fully reduce the pH value in an effective time, can prolong the action time, and achieves the effect of continuously reducing the pH value in the whole feeding process. Meanwhile, the compound enzyme preparation can improve the digestion and absorption of fat and protein nutrient substances and improve the nutritional overfeeding caused by fat and protein indigestion, thereby improving the overfeeding problem of piglets through interaction and cooperation.

Description

Feed additive for improving overfeeding of piglets, feed and additive preparation method
Technical Field
The invention relates to the field of feed additives, in particular to a feed additive for improving the overfeeding of piglets, a feed and a preparation method of the additive.
Background
At present, the most common and serious problem in the process of piglet cultivation is the overfeeding problem after weaning, wherein the overfeeding means that undigested feed particles exist in the piglet excrement and the excrement is represented as white urate with unformed excrement and external sign; the feces contain yellow macroscopic undigested feed particles and sometimes watery feces. Through analysis, factors causing the phenomenon of overfeeding of the piglets may be as follows: 1. the nutritional diseases are caused by the following obvious characteristics: the excrement forming degree is poor, the feed intake is reduced, the feed reward is low, the slaughter weight is reduced, and the possible reasons are caused by vitamin A deficiency, insufficient feed energy or indigestion after extra grease is added into daily ration; 2. infectious diseases, many of which cause intestinal damage, can cause dysbacteriosis in the intestinal tracts of piglets, thereby causing transient diarrhea or overfeeding. The long-time overfeeding can cause the growth performance and nutrient utilization rate of the piglets to be reduced, the feed conversion rate is reduced, the production benefit is seriously damaged, and great economic loss is caused to farmers.
The plant extract is derived from plants, has one or more biological functions, and can promote intestinal health, enhance immunity, and improve livestock and poultry growth performance when added into feed. The main effects are as follows: 1. regulating the digestive tract balance of animals; 2. promoting the digestion and absorption of animal organism to nutrient substance; 3. improving the immunity and disease resistance of animals. Therefore, based on the above effects, some scholars try to directly add plant extracts to the daily ration of the piglets and try to adjust the intestinal flora balance of the piglets by adding the plant extracts so as to improve the overfeeding phenomenon. However, through a large number of animal feeding experiments, the test results all show that: after the plant extract is added into the piglet diet, the phenomena of water excrement and feed excrement caused by overfeeding are not obviously reduced, namely the plant extract in the existing scheme can not well play the role of obviously improving the intestinal health of the piglets and reducing the overfeeding. By analysis, the possible reasons are: 1. although the plant extract has certain acid resistance and bile resistance, if the plant extract is not specially treated, the plant extract is easily corroded by gastric acid when passing through a special environment of piglet gastric juice, so that the activity of the plant extract is greatly reduced, and the plant extract cannot play a normal effect after entering intestinal tracts of piglets; 2. the plant extract can be a nutritional overfeeding material, and if the plant extract is simply added to improve the intestinal environment, the improvement effect can not be achieved, and the phenomena of water excrement and feed excrement can not be relieved.
Disclosure of Invention
The invention aims to provide a feed additive for improving the overfeeding of piglets, a feed and a preparation method of the additive, so as to improve the overfeeding condition of the piglets and improve the breeding quality of the piglets.
The invention provides a feed additive for improving the overfeeding of piglets, which is characterized in that: the composite material comprises the following components in percentage by weight: 5-10% of plant extract; 1-3% of compound acidifier; 3-8% of mannan oligosaccharide; 1-3% of complex enzyme preparation; the balance being carriers.
Further, the plant extract is one or more compounds of yucca extract, plant essential oil, blue algae extract, carvacrol and thymol.
Further, the plant extract comprises, in weight percent: 50-60% of yucca extract; 10-20% of plant essential oil; 10% of blue algae extract; 10% of carvacrol; and 10% of thymol.
Further, the compound acidifier is one or more compounds of citric acid, lactic acid, fumaric acid, acetic acid and propionic acid.
Further, the compound acidifier comprises the following components in percentage by weight: 50-60% of citric acid; 10-20% of lactic acid; 10% of fumaric acid, 10% of caproic acid and 10% of propionic acid.
Further, the compound enzyme preparation comprises the following components in percentage by weight: 20% of acid protease, 20% of neutral protease, 30-40% of alkaline protease, 10-20% of lipase and 10% of glucose oxidase.
Further, the enzyme activity range of the acid protease in the compound enzyme preparation is more than or equal to 20,000U/g, and is less than or equal to 50,000U/g; the enzyme activity range of the neutral protease is more than or equal to 10,000U/g and less than or equal to 20,000U/g; the enzyme activity range of the alkaline protease is more than or equal to 20,000U/g and less than or equal to 50,000U/g; the lipase activity range is more than or equal to 10,000U/g and less than or equal to 20,000U/g; the enzyme activity range of the glucose oxidase is more than or equal to 1,000U/g, and is less than or equal to 2,000U/g.
Further, the paint comprises the following components in percentage by weight: 5-7% of plant extract; 2% of compound acidifier; 5% of mannan oligosaccharide; 2% of complex enzyme preparation; 82-84% of carrier.
The invention also provides a feed for improving the overfeeding of the piglets, which comprises the feed additive for improving the overfeeding of the piglets.
The invention also provides a preparation method of the feed additive for improving the overfeeding of the piglets, which comprises the following steps:
s1, compounding plant extracts according to the corresponding proportion;
s2, weighing the compound acidifier prepared according to the corresponding proportion, weighing the carrier and the plant extract in the S1 for compounding, compounding the compound acidifier, the carrier and the plant extract, and stirring for 10-20min for uniformly mixing to ensure that the plant extract is wrapped by the compound acidifier and the carrier as much as possible;
s3, weighing the complex enzyme preparation prepared according to the corresponding proportion, compounding the complex enzyme preparation and the carrier, stirring for 10-20min to mix uniformly, and mixing various complex enzyme preparations as uniformly as possible;
s4, weighing the mannooligosaccharides prepared according to the corresponding proportion, adding the mannooligosaccharides, the complex enzyme preparation and the carrier compounded in the S3 into the compound in the S2 for 3 times, stirring for 5-8min after the first two times of addition, and stirring for about 10-20min after the third time of addition so as to uniformly mix the additives as much as possible.
And S5, metering and packaging.
The invention has the technical effects that: the plant extract maintains the micro-ecological balance of the flora in the digestive tract by bacteriostasis and antibiosis and selective inhibition of bacteria, so as to protect the intestinal health of livestock and poultry, and simultaneously can interact with the compound acidifier to form a synergistic effect, thereby not only resisting the erosion of gastric acid, but also showing that the plant extract and the compound acidifier can jointly act on pathogenic bacteria. The plant extract can penetrate cell membranes and intervene in metabolism of pathogenic bacteria, once the plant extract penetrates the cell membranes, the plant extract can assist the composite acidifying agent to smoothly pass through, once the composite acidifying agent enters the pathogenic bacteria, osmotic pressure can be changed, loss and exhaustion of energy of the pathogenic bacteria are caused, the pH value can be sufficiently reduced within an effective time, the action can be prolonged, and the effect of continuously reducing the pH value in the whole feeding process is achieved. The compound enzyme preparation can improve the digestion and absorption of the fat protein nutrient substances and improve the nutritional overfeeding caused by fat protein indigestion, thereby improving the overfeeding of the piglets through interaction and cooperation.
Drawings
FIG. 1 is a diagram showing the statistics of the pH of a feed additive containing plant extracts in the gastric juice;
fig. 2 is a statistical graph of the effect of the addition of the feed additives of examples 10, 11, 12 on the post-gut fermented protein of piglets.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention provides a feed additive for improving the overfeeding of piglets, which comprises the following components in percentage by weight: 5-10% of plant extract; 1-3% of compound acidifier; 3-8% of mannan oligosaccharide; 1-3% of complex enzyme preparation; the balance being carriers.
Wherein the plant extract is one or more compounds selected from Yucca schidigera extract, plant essential oil, blue algae extract, carvacrol and thymol.
More specifically, the plant extract comprises the following components in percentage by weight: 50-60% of yucca extract; 10-20% of plant essential oil; 10% of blue algae extract; 10% of carvacrol; and 10% of thymol. The invention specifically lists the optimal mixture ratio combination of 3 plant extracts, such as examples 1-3.
Example 1:
the plant extract comprises the following components in percentage by weight: yucca extract 55%; 15% of plant essential oil; 10% of blue algae extract; 10% of carvacrol; and 10% of thymol.
Example 2:
the plant extract comprises the following components in percentage by weight: 50% of yucca extract; 20% of plant essential oil; 10% of blue algae extract; 10% of carvacrol; and 10% of thymol.
Example 3:
the plant extract comprises the following components in percentage by weight: 50% of yucca extract; 20% of plant essential oil; 10% of blue algae extract; 10% of carvacrol; and 10% of thymol.
The compound acidifier is one or more of citric acid, lactic acid, fumaric acid, acetic acid and propionic acid.
More specifically, the composite acidifier comprises the following components in percentage by weight: 50-60% of citric acid; 10-20% of lactic acid; 10% of fumaric acid, 10% of caproic acid and 10% of propionic acid. The invention details the optimal proportioning combination of 3 of the compound acidifier, such as examples 4-6.
Example 4:
according to weight percentage, the composite acidifier comprises the following components: 50% of citric acid, 20% of lactic acid, 10% of fumaric acid, 10% of hexanoic acid and 10% of propionic acid.
Example 5:
according to weight percentage, the composite acidifier comprises the following components: 55% of citric acid, 15% of lactic acid, 10% of fumaric acid, 10% of hexanoic acid and 10% of propionic acid.
Example 6:
according to weight percentage, the composite acidifier comprises the following components: 60% of citric acid, 10% of lactic acid, 10% of fumaric acid, 10% of hexanoic acid and 10% of propionic acid.
In the invention, the enzyme activity range of the acid protease in the compound enzyme preparation is more than or equal to 20,000U/g, and is less than or equal to 50,000U/g; the enzyme activity range of the neutral protease is more than or equal to 10,000U/g and less than or equal to 20,000U/g; the enzyme activity range of the alkaline protease is more than or equal to 20,000U/g and less than or equal to 50,000U/g; the lipase activity range is more than or equal to 10,000U/g and less than or equal to 20,000U/g; the enzyme activity range of the glucose oxidase is more than or equal to 1,000U/g, and is less than or equal to 2,000U/g.
Specifically, the complex enzyme preparation comprises the following components in percentage by weight: 20% of acid protease, 20% of neutral protease, 30-40% of alkaline protease, 10-20% of lipase and 10% of glucose oxidase. The invention details the optimal proportioning combination in 3 of the complex enzyme preparation, such as examples 7-9.
Example 7:
according to the weight percentage, the complex enzyme preparation comprises the following components: 20% of acid protease, 20% of neutral protease, 30% of alkaline protease, 20% of lipase and 10% of glucose oxidase.
Example 8:
according to the weight percentage, the complex enzyme preparation comprises the following components: 20% of acid protease, 20% of neutral protease, 35% of alkaline protease, 15% of lipase and 10% of glucose oxidase.
Example 9:
according to the weight percentage, the complex enzyme preparation comprises the following components: 20% of acid protease, 20% of neutral protease, 40% of alkaline protease, 10% of lipase and 10% of glucose oxidase.
The invention specifically lists the optimal mixture ratio combination of 3 feed additives for improving the overfeeding of piglets, as in examples 10-12.
Example 10:
the feed additive for improving the piglet overfeeding comprises the following components in percentage by weight: 5% of plant extract; 2% of compound acidifier; 5% of mannan oligosaccharide; 2% of complex enzyme preparation; and (4) carrier 84%.
Example 11:
the feed additive for improving the piglet overfeeding comprises the following components in percentage by weight: 6% of plant extract; 2% of compound acidifier; 5% of mannan oligosaccharide; 2% of complex enzyme preparation; and (3) carrier.
Example 12:
the feed additive for improving the piglet overfeeding comprises the following components in percentage by weight: 7% of plant extract; 2% of compound acidifier; 5% of mannan oligosaccharide; 2% of complex enzyme preparation; and 82% of carrier.
In the invention, the mannooligosaccharides are obtained by yeast fermentation, and the carrier is corn starch, wheat bran, rice bran or an inorganic compound feed carrier.
The invention also provides a method for preparing the feed additive for improving the overfeeding of the piglets, which comprises the following steps:
s1, compounding plant extracts according to the corresponding proportion;
s2, weighing the compound acidifier prepared according to the corresponding proportion, weighing the carrier and the plant extract in the S1 for compounding, compounding the compound acidifier, the carrier and the plant extract, and stirring for 10-20min for uniformly mixing to ensure that the plant extract is wrapped by the compound acidifier and the carrier as much as possible;
s3, weighing the complex enzyme preparation prepared according to the corresponding proportion, compounding the complex enzyme preparation and the carrier, stirring for 10-20min to mix uniformly, and mixing various complex enzyme preparations as uniformly as possible;
s4, weighing the mannooligosaccharides prepared according to the corresponding proportion, adding the mannooligosaccharides, the complex enzyme preparation and the carrier compounded in the S3 into the compound in the S2 for 3 times, stirring for 5-8min after the first two times of addition, and stirring for about 10-20min after the third time of addition so as to uniformly mix the additives as much as possible.
And S5, metering and packaging.
The invention further provides a feed for improving the overfeeding of the piglets, and the additive in the feed is the feed additive for improving the overfeeding of the piglets.
The composite material comprises the following components in percentage by weight: 0.02-0.05% of feed additive and 99.5-99.8% of base material, wherein the additive is the feed additive for improving the overfeeding of the piglets as claimed in any one of claims 1-8.
The efficacy of the feed additive of the invention is verified by various tests below.
And (3) experimental design:
150 weaned piglets of 21 days old and 150 grown healthy piglets with the weight (7.21+0.65) kg are selected in the test, and are randomly divided into 5 groups according to the principle of similar heredity and weight, each group is repeated for 3 times, each group is repeated for 10 times, and male and female halves are mixed and fed. The first group was the basal diet with antibiotic addition (i.e. positive control group), the second group was the basal diet without antibiotic addition (i.e. negative control group), and the third, fourth and fifth groups were negative control groups with 300g/T addition of each of examples 10, 11 and 12, as shown in Table 1 below.
TABLE 1 feeding test design
Treatment group Type of ration Type of addition Additive amount (g/T)
First group (positive control group) Basal diet + flavomycin ---
Second group (negative control group) Antibiotic-free group ---
Third group Antibiotic-free group Example 10 300
Fourth group Antibiotic-free group Example 11 300
Fifth group Antibiotic-free group Example 12 300
Test 1: verification test of the pH regulation and control of feed additive containing plant extract in gastric juice:
after 8:00 feeding in the morning of the 28 th day of the experiment, 2 healthy piglets were slaughtered for each treatment, the abdominal cavity was opened rapidly, the content in the gastric juice was collected under aseptic conditions, the pH dynamic change within 3h was measured once every 0.5h, and 7 times in total.
Test 2: verification test of the microbial count of the feed additive containing the plant extract in the caecum:
on day 28 of the trial, 2 piglets with near-average body weight and good health status were selected from each replicate and anesthetized with 4% sodium phenobarbital. After anaesthesia is completed, the jugular vein of the piglet is bled, the abdominal cavity is cut along the midline of the abdomen, the middle intestine of the cecum is taken, the two ends are subjected to double ligation, the cecum is wrapped by tinfoil paper and a preservative film, the mark is made, the cecum is placed in liquid nitrogen for quick freezing, and the cecum is transferred to the temperature of minus 80 ℃ for storage.
Test 3: the feed additive containing the plant additive can reduce the proportion of the post-intestinal fermentation protein by a verification test:
on day 28 of the trial, 2 piglets with near-average body weight and good health status were selected from each replicate and anesthetized with 4% sodium phenobarbital. After anaesthesia is completed, jugular vein bloodletting is carried out on the piglet, the abdominal cavity is cut along the midline of the abdomen, 500g of the content of the hindgut is taken, packaged and marked, the piglet is placed in a low-temperature refrigerator, and the protein content of the piglet is measured by using a Kjeldahl apparatus.
Test 4: the application of the feed additive containing the plant extract in improving the forage passing of the piglets is as follows:
measurement of growth Performance: accurately weighing and recording the weight of the feed and the weight of the residual feed in each repeated process, and calculating the average daily feed intake of each piglet; weighing on empty stomach 8:00 in the morning of day 0 and day 28 of the test, and calculating the average daily gain of each piglet; and finally, calculating the material-weight ratio according to the average daily feed intake and the average daily gain.
Stool index scoring: feces evaluation was performed by observing the feces formation status on days 7, 14, 21, and 28 of the test, respectively, and feces were collected from each multiplexing feces receiving plate, and fresh feces were scored by observing 5 points, 4 corners, and the middle, each observation point defining an area 20 cm bounded by each observation point. The small intestine feces are scored, the caecum feces are not scored, and the scoring standard adopts a 4-point system. 1, hard excrement can be picked up and rolled in hands; 2, the excrement is formed, but the inside of the excrement is in a wet state; 3, dividing into thin manure; 4, dividing into water samples.
Test results
(1) Referring to FIG. 1, FIG. 1 is a statistical graph showing the dynamic change of pH control in gastric juice of a feed supplement containing plant extracts, and it can be seen from FIG. 1 that the pH of the positive control group and the negative control group decreases rapidly within 1 hour, while it generally takes at least 2 hours for food to leave the stomach, whereas the test results of examples 10, 11 and 12 show that the pH decreases gradually within 3 hours, so as to prolong the action time and achieve the effect of continuously decreasing the pH after the whole feeding process.
(2) Table 2 shows the results of the effect of the feed additive of the invention on the number of cecal microorganisms.
Table 2 variation of the number of microorganisms in the cecum by addition of the feed additives of examples 10, 11 and 12
Figure BDA0003020604970000081
As can be seen from Table 2, compared with the second group, after the feed additives of examples 10, 11 and 12 are added, the number of harmful bacteria Escherichia coli is remarkably reduced, the number of beneficial bacteria Lactobacillus and Bifidobacterium is remarkably increased, and the effect is remarkable. This demonstrates that the feed additives of examples 10, 11 and 12 can reduce the number of harmful bacteria in the caecum and increase the number of beneficial bacteria.
(3) Referring to fig. 2, fig. 2 is a statistical chart showing the effect of the feed additives of examples 10, 11 and 12 on the post-intestinal fermented protein of piglets, and as can be seen from fig. 2, compared with the first group, the fermented protein in the post-intestinal is reduced to different degrees, namely, 28.1%, 36.0% and 40.6% respectively, after the feed additives of examples 10, 11 and 12 are added, and the effect is significant. This shows that the addition of the feed additive can effectively reduce the number of harmful microorganisms in the hindgut, and the utilization rate of the fermented protein by the harmful bacteria is reduced, thereby reducing the fermentation harmful substances. The most direct expression of the piglet intestinal health problem caused by the post-intestinal fermented protein is diarrhea, and the reduction of the post-intestinal protein means that the incidence rate of the diarrhea is reduced and the overfeeding phenomenon is improved, so that the health of the piglets is ensured.
(4) Table 3 shows the results of the change in growth performance of piglets after addition of the feed additive according to the invention.
TABLE 3 Effect of the addition of the feed additives of examples 10, 11 and 12 on the growth Performance of piglets
Figure BDA0003020604970000091
As can be seen from Table 3, compared with the first group and the second group, the daily feed intake and the daily weight gain are increased, the feed-weight ratio is reduced, the effect is obvious, the diarrhea rate is obviously reduced, and the overfeeding phenomenon is obviously improved after the feed additives of the examples 10, 11 and 12 are added, which shows that the overfeeding phenomenon of the piglets is effectively improved, the diarrhea rate is reduced, the production performance is improved in all aspects after the feed additives of the examples 10, 11 and 12 are added, and the specific results are shown in Table 4.
TABLE 4 Effect of the addition of the feed additives of examples 10, 11 and 12 on the faecal status of piglets
Figure BDA0003020604970000092
As can be seen from Table 4, compared with the first and second groups, the scores of the pig excrements are reduced to different degrees after the addition of the feed additives of examples 10, 11 and 12, namely, the excrements are more formable and have higher hardness, which shows that the feed additive can improve the microbial flora in the pig intestinal tract, promote the proliferation of beneficial bacteria and reduce harmful bacteria, so that the protein in the feeding ration is fully and effectively decomposed, the undigested protein ration is reduced, the fermentation of the hindgut is improved, the overfeeding is improved, and the diarrhea degree of the excrements is reduced.
The invention is additionally provided with a test 5: nutrient utilization rate of feed additive containing plant extract
1. In the experiment, 2 pigs from each group were selected and placed in a metabolism cage for free drinking and feeding. The whole test period is divided into a pre-feeding period and a positive feeding period for 6 days. Pre-feeding period 3d, pre-feeding 3 days after weaning with 0.5% TiO2Feeding; and 3d of a pilot period, starting to collect feces, continuously collecting for 3 days, wherein the feces are collected at 10:00 am and 8 pm: 00 collecting feces, then removing feathers and scurf from the collected feces, and spraying 5mL of 10% hydrochloric acid solution per 100g of the collected feces. And putting the feces samples collected for 3 days into a 65 ℃ oven to be dried to constant weight by taking repetition as a unit, dampening the feces samples for 24 hours at room temperature, crushing the feces samples and sieving the feces samples with a 40-mesh sieve to prepare air-dried samples, and storing the air-dried samples in a refrigerator at the temperature of-20 ℃ to be tested, crude protein, crude fat and energy.
2. Measurement index and method
Determining dry substances in the feed and the excrement by referring to a method of GB/T6435-; the content of the crude protein is measured by using a FOSSKjeltec2300 full-automatic Kjeltec instrument; the crude fat content is measured by an SZC-C type fat measuring instrument of Shanghai fiber inspection; energy was measured using an IKAC2000 calorimeter.
3. The test results are shown in table 5.
TABLE 5 Effect of the addition of the feed additives of examples 10, 11 and 12 on the nutrient utilization
Figure BDA0003020604970000101
As can be seen from Table 5, in the present invention, the addition of the feed additives of examples 10, 11 and 12 significantly improved the utilization of dry matter and crude fat, and increased the utilization of crude protein, total energy and apparent metabolic energy, as compared with the first and second groups. Therefore, the feed additives of examples 10, 11 and 12 can improve intestinal flora, increase the number of beneficial bacteria, reduce the proliferation of harmful bacteria, improve the overfeeding phenomenon of piglets, reduce the diarrhea rate, and improve the absorption of nutrient substances, thereby improving the feed utilization rate and the breeding benefit.
In conclusion, the feed additive does not contain antibiotics, can improve the phenomenon of overfeeding of the piglets, and has the effects of bacteriostasis, antibiosis and growth promotion. Specifically, the plant extract maintains the microecological balance of the flora in the digestive tract by bacteriostasis and antibiosis and selective inhibition of bacteria, so that the intestinal health of livestock and poultry is protected, and the plant extract can interact with a compound acidifier to form a synergistic effect, so that the gastric acid erosion can be resisted, and the plant extract and the compound acidifier can jointly act on pathogenic bacteria. The plant extract can penetrate cell membranes and intervene in metabolism of pathogenic bacteria, once the plant extract penetrates the cell membranes, the plant extract can assist the composite acidifying agent to smoothly pass through, once the composite acidifying agent enters the pathogenic bacteria, osmotic pressure can be changed, loss and exhaustion of energy of the pathogenic bacteria are caused, the pH value can be sufficiently reduced within an effective time, the action can be prolonged, and the effect of continuously reducing the pH value in the whole feeding process is achieved.
The mannan oligosaccharide can be used as a prebiotic and has obvious probiotic effect, anaerobic bacteria such as bifidobacteria and lactic acid bacteria in intestinal tracts can utilize the mannan oligosaccharide for anabolism, aerobic pathogenic bacteria cannot utilize the mannan oligosaccharide, so that the proliferation of beneficial bacteria is facilitated, and the number of harmful bacteria is reduced. Meanwhile, various proteases contained in the compound enzyme preparation can further decompose the fermented protein in the hindgut, improve the hydrolysis rate of the fermented protein, reduce the harmful microorganisms from fermenting by using the fermented protein as a substrate, generate a large amount of harmful substances, improve the intestinal health, improve the nutritional overfeeding of the piglets and reduce the diarrhea.
It should be noted that, in this document, terms such as "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (10)

1. A feed additive for improving the overfeeding of piglets is characterized in that: the composite material comprises the following components in percentage by weight: 5-10% of plant extract; 1-3% of compound acidifier; 3-8% of mannan oligosaccharide; 1-3% of complex enzyme preparation; the balance being carriers.
2. The feed additive of claim 1, wherein: the plant extract is one or more of yucca extract, plant essential oil, blue algae extract, carvacrol and thymol.
3. The feed additive of claim 2, wherein: the plant extract comprises the following components in percentage by weight: 50-60% of yucca extract; 10-20% of plant essential oil; 10% of blue algae extract; 10% of carvacrol; and 10% of thymol.
4. The feed additive for improving the overfeeding of the piglets as claimed in claim 1, which is characterized in that: the compound acidifier is one or more compounds of citric acid, lactic acid, fumaric acid, acetic acid and propionic acid.
5. The feed additive according to any one of claims 1 to 4, wherein: the compound acidifier comprises the following components in percentage by weight: 50-60% of citric acid; 10-20% of lactic acid; 10% of fumaric acid, 10% of caproic acid and 10% of propionic acid.
6. The feed additive of claim 1, wherein: the compound enzyme preparation comprises the following components in percentage by weight: 20% of acid protease, 20% of neutral protease, 30-40% of alkaline protease, 10-20% of lipase and 10% of glucose oxidase.
7. The feed additive of claim 6, wherein: the enzyme activity range of the acid protease in the compound enzyme preparation is more than or equal to 20,000U/g, and is less than or equal to 50,000U/g; the enzyme activity range of the neutral protease is more than or equal to 10,000U/g and less than or equal to 20,000U/g; the enzyme activity range of the alkaline protease is more than or equal to 20,000U/g and less than or equal to 50,000U/g; the lipase activity range is more than or equal to 10,000U/g and less than or equal to 20,000U/g; the enzyme activity range of the glucose oxidase is more than or equal to 1,000U/g, and is less than or equal to 2,000U/g.
8. The feed additive of claim 1, wherein: the composite material comprises the following components in percentage by weight: 5-7% of plant extract; 2% of compound acidifier; 5% of mannan oligosaccharide; 2% of complex enzyme preparation; 82-84% of carrier.
9. The feed for improving the overfeeding of the piglets is characterized in that: the feed additive for improving the overfeeding of the piglets as claimed in any one of claims 1 to 8 is contained in the feed.
10. A preparation method of a feed additive for improving the overfeeding of piglets is characterized by comprising the following steps: the method comprises the following steps:
s1, compounding plant extracts according to the corresponding proportion in any one of claims 1-3 and 8;
s2, weighing the compound acidifier according to the proportion in any one of claims 1, 4-5 and 8, compounding with the carrier and the plant extract, and stirring for 10-20min to mix uniformly so that the plant extract is wrapped by the compound acidifier and the carrier;
s3, weighing the complex enzyme preparation with the proportion in any one of claims 1 and 6-8, compounding with the carrier, and stirring for 10-20min to mix uniformly;
s4, weighing the mannooligosaccharides with the proportion in the claim 1 or 8, and adding the mannooligosaccharides, the complex enzyme preparation and the carrier which are compounded in the S3 into the compound in the S2 for 3 times;
and S5, metering and packaging.
CN202110401698.8A 2021-04-14 2021-04-14 Feed additive for improving overfeeding of piglets, feed and additive preparation method Withdrawn CN112998150A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114304413A (en) * 2021-12-28 2022-04-12 福建傲农生物科技集团股份有限公司 Composite containing acidifying agent and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114304413A (en) * 2021-12-28 2022-04-12 福建傲农生物科技集团股份有限公司 Composite containing acidifying agent and preparation method thereof

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Application publication date: 20210622